NIH Guide + NIH RePORTER

Open NIH NOFOs: Due Dates, Institutes & Funded Projects

Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards

NIH has 380 open notices of funding opportunity. The NIH Guide spreads each one across its own page, participation and due-date notices, and NOSIs. Each page here puts them together, and adds how many projects NIH actually funded under that NOFO.

Open now

349

Accepting applications

Opening soon

31

Posted, open date ahead

Due in 30 days

117

Next due date by Nov 15, 2026

With funding history

305

Funded projects under it or its predecessor

Due in the next 30 days

107 more in the full list below, sorted by next due date.

All NIH NOFOs

Search by NOFO number, title words, institute, or activity code. Filters stay in the address bar, so a filtered list can be bookmarked or shared.

380 NOFOs open or opening soon

NIH notices of funding opportunity with due dates and funded projects
NOFONext due
PAS-27-028
Science Track Award for Research Transition (START) Program (R03, Clinical Trial Optional)
PAS · NIDA + 1 more · R03
Oct 16, 2026
PAR-27-074
Limited Competition: Small Grant Program for Mentored Research Career Development Award Recipients (R03) (Clinical Trials Not Allowed)
PAR · NIAMS + 1 more · R03
Oct 16, 2026
PAR-27-015
Community-Based Participatory Research to Advance Data and Practice Transformation (ADAPT) for Optimizing Oral Health for All (UG3/UH3 Clinical Trial Optional)
PAR · NIDCR + 5 more · UG3, UH3
Oct 16, 2026
PAR-25-370
Ethical, Legal and Social Implications (ELSI) Small Research Grant (R03 Clinical Trial Optional)
PAR · NHGRI + 13 more · R03
Oct 16, 2026
PAR-25-091
Limited Competition: Small Grant Program for NIDDK K01/K08/K23/K25 Recipients (R03 Clinical Trial Optional)
PAR · NIDDK + 1 more · R03
Oct 16, 2026
PAR-25-358
NEI Clinical Research Study Planning Grant Program (R34 Clinical Trial Not Allowed)
PAR · NEI + 1 more · R34
Oct 16, 2026
PAR-24-329
Development and Testing of Novel Interventions to Improve HIV Prevention, Treatment, and Program Implementation for People Who Use Substances (R34 Clinical Trial Required)
PAR · NIDA + 1 more · R34
Oct 16, 2026
PAR-25-068
Pilot Studies of Biological, Behavioral and Social Mechanisms Contributing to HIV Pathogenesis Within the Mission of NIDDK (R21 Clinical Trial Not Allowed)
PAR · NIDDK + 1 more · R21
Oct 16, 2026
PAR-25-357
NEI Research Grant for Vision-Related Secondary Data Analysis (R21 Clinical Trial Not Allowed)
PAR · NEI + 1 more · R21
Oct 16, 2026
PAR-25-284
Innovative Pilot Mental Health Services Research Not Involving Clinical Trials (R34 Clinical Trial Not Allowed)
PAR · NIMH + 1 more · R34
Oct 16, 2026
PA-25-302
NIH Small Research Grant Program (Parent R03 Clinical Trial Not Allowed)
PA · NIH + 14 more · R03
Oct 16, 2026
PA-25-304
NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Not Allowed)
PA · NIH + 22 more · R21
Oct 16, 2026
PA-25-306
NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Required)
PA · NIH + 17 more · R21
Oct 16, 2026
PAR-25-032
NHLBI Clinical Trial Pilot Studies (R34 Clinical Trial Optional)
PAR · NHLBI + 1 more · R34
Oct 16, 2026
PAR-25-346
Exploratory/Developmental Bioengineering Research Grants (EBRG) (R21 Clinical Trial Not Allowed)
PAR · NCI + 1 more · R21
Oct 16, 2026
PAR-25-321
Exploratory/Developmental Bioengineering Research Grants (EBRG) (R21 Clinical Trial Optional)
PAR · NCI + 1 more · R21
Oct 16, 2026
PAR-25-100
Pilot Health Services and Economic Research on the Treatment of Drug, Alcohol, and Tobacco Use Disorders (R34 Clinical Trial Optional)
PAR · NIDA + 1 more · R34
Oct 16, 2026
PAR-25-266
Innovative Screening Approaches and Therapies for Screenable Disorders in Newborns (R21 - Clinical Trial Optional)
PAR · NICHD + 1 more · R21
Oct 16, 2026
PAR-25-159
Prevention and Intervention Approaches for Fetal Alcohol Spectrum Disorders (R34 Clinical Trial Optional)
PAR · NIAAA + 1 more · R34
Oct 16, 2026
PAR-25-272
New Approaches for Measuring Brain Changes Across Longer Timespans (R21 Clinical Trial Optional)
PAR · NIA + 2 more · R21
Oct 16, 2026
PAR-25-288
Navigator Emergency Department Diversion Models for Non-Urgent Mental Health Concerns (R34 Clinical Trial Required)
PAR · NIMH + 1 more · R34
Oct 16, 2026
PAR-25-282
Mood and Psychosis Symptoms during the Menopause Transition (R21 Clinical Trial Optional)
PAR · NIMH + 1 more · R21
Oct 16, 2026
PAR-25-291
Utilizing Invasive Recording and Stimulating Opportunities in Humans to Advance Neural Circuitry Understanding of Mental Health Disorders (R21 Clinical Trial Optional)
PAR · NIMH + 1 more · R21
Oct 16, 2026
PAR-25-286
Neuromodulation/Neurostimulation Device Development for Mental Health Applications (R21 Clinical Trial Not Allowed)
PAR · NIMH + 1 more · R21
Oct 16, 2026
PA-25-125
NICHD Small Research Grant Program (R03 Clinical Trial Required)
PA · NICHD + 1 more · R03
Oct 16, 2026
PAR-25-070
Mechanisms that Impact Cancer Risk with Use of Incretin Mimetics (R21 Clinical Trial Not Allowed)
PAR · NCI + 1 more · R21
Oct 16, 2026
PAR-25-105
NIDCR Small Grant Program for New Investigators (R03 Clinical Trial Not Allowed)
PAR · NIDCR + 1 more · R03
Oct 16, 2026
PAR-25-113
Advancement and Innovation in Measurement of Language Development and Predictors (R21 Clinical Trial Not Allowed)
PAR · NICHD + 1 more · R21
Oct 16, 2026
PAR-25-124
NCMRR Early Career Research Award (R03 Clinical Trial Optional)
PAR · NICHD + 1 more · R03
Oct 16, 2026
PAR-25-244
Basic Research in Cancer Health Disparities (R21 Clinical Trial Not Allowed)
PAR · NCI + 1 more · R21
Oct 16, 2026
PAR-25-256
Developing novel theory and methods for understanding the genetic architecture of complex human traits (R21 Clinical Trial Not Allowed)
PAR · NHGRI + 1 more · R21
Oct 16, 2026
PAR-25-273
Development of Animal Models and Related Biological Materials for Research (R21 Clinical Trial Not Allowed)
PAR · ORIP + 1 more · R21
Oct 16, 2026
PA-25-253
Exploratory Grants in Cancer Control (R21 Clinical Trial Optional)
PA · NCI + 1 more · R21
Oct 16, 2026
PAR-25-077
CCRP Initiative: NIH Countermeasures Against Chemical Threats (CounterACT) Basic Research on Chemical Threats that Affect the Nervous System (R01 Clinical Trial Not Allowed)
PAR · NINDS + 1 more · R01
Oct 16, 2026
PAR-25-143
Dissemination and Implementation Research in Health (R21 Clinical Trial Optional)
PAR · NCI + 19 more · R21
Oct 16, 2026
PAR-25-233
Dissemination and Implementation Research in Health (R03 Clinical Trial Not Allowed)
PAR · NCI + 13 more · R03
Oct 16, 2026
PAR-25-122
Pilot Projects Investigating Understudied Proteins Associated with Rare Diseases (R03 Clinical Trial Not Allowed)
PAR · NCATS + 5 more · R03
Oct 16, 2026
PA-25-093
Limited Competition: CCRP Initiative: Promoting a Basic Understanding of Chemical Threats to Skin (R34 Clinical Trial Not Allowed)
PA · NIAMS + 1 more · R34
Oct 16, 2026
PAR-25-044
Mechanisms that Impact Cancer Risk after Bariatric Surgery (R21 Clinical Trial Not Allowed)
PAR · NCI + 1 more · R21
Oct 16, 2026
RFA-RM-27-012
PRIMED-AI: Data-to-Model Academic-Industrial Partnerships (D2M-AIP) for Precision Medicine with AI: Integrating Imaging with Multimodal Data (UG3/UH3 Clinical Trial Optional)
RFA · RMOD + 2 more · UG3, UH3
Oct 19, 2026
RFA-RM-27-013
Model-to-Clinic (M2C) for Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) (UG3/UH3, Clinical Trial Optional)
RFA · RMOD + 2 more · UG3, UH3
Oct 19, 2026
RFA-CA-27-019
Early-Stage Development of Informatics Technologies for Cancer Research and Management (U01 Clinical Trial Optional)
RFA · NCI + 1 more · U01
Oct 19, 2026
RFA-CA-27-020
Advanced Development of Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional)
RFA · NCI + 1 more · U24
Oct 19, 2026
RFA-CA-27-021
Sustained Support for Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional)
RFA · NCI + 1 more · U24
Oct 19, 2026
RFA-DE-27-001
Community Engagement Evaluation and Data Coordination (CEED) Hub to Advance Data and Practice Transformation for Optimizing Oral Health for All (U01, Clinical Trial Not Allowed)
RFA · NIDCR + 4 more · U01
Oct 19, 2026
PAR-25-343
NIDCD Cooperative Agreement for Clinical Trials in Communication Disorders (U01 - Clinical Trial Required)
PAR · NIDCD + 1 more · U01
Oct 19, 2026
PAR-25-155
Limited Competition: Small Grant Program for the NCATS Clinical and Translational Science Award (CTSA) Program (R03 Clinical Trial Optional)
PAR · NCATS + 1 more · R03
Oct 19, 2026
PAR-25-296
Limited Competition: Clinical and Translational Science Award (CTSA) Program: Collaborative and Innovative Acceleration Award (UG3/UH3 Clinical Trial Optional)
PAR · NCATS + 10 more · UG3, UH3
Oct 19, 2026
PAR-25-158
Prevention and Intervention Approaches for Fetal Alcohol Spectrum Disorders (R61/R33 Clinical Trial Optional)
PAR · NIAAA + 1 more · R61, R33
Oct 19, 2026
PAR-25-226
Seamless Early-Stage Clinical Drug Development (Phase 1 to 2a) for Novel therapeutic Agents for the Spectrum of Alzheimer's Disease (AD) and AD-related Dementias (ADRD) (UG3/UH3 Clinical Trial Required)
PAR · NIA + 1 more · UG3, UH3
Oct 19, 2026

* Funded projects under the NOFO it reissues; the new number has no awards yet.

NIH NOFO questions

What is an NIH NOFO?

A Notice of Funding Opportunity (NOFO, formerly FOA) is the announcement NIH publishes in the NIH Guide for Grants and Contracts to invite applications. It sets the activity code, participating institutes, eligibility, budget, due dates, and review criteria. Every NIH grant application is submitted under a NOFO number such as PA-25-301.

What is the difference between a PA, PAR, and RFA?

A PA (Program Announcement) is an ongoing invitation, usually with standard due dates; parent announcements such as the parent R01 are PAs. A PAR is a program announcement with special receipt, referral, or review, often with its own due dates and a dedicated review panel. An RFA (Request for Applications) is a one-time solicitation with set-aside funds and usually a single due date.

Why does one NOFO have so many notices?

After posting, NIH changes a NOFO through separate notices in the NIH Guide: another institute joining (a participation notice), due-date changes, early expiration, or policy updates. Notices of Special Interest (NOSIs) are attached separately to signal topics an institute wants to fund through it. Each GotGrant NOFO page lists the related notices and active NOSIs together.

How are funded projects counted?

Funded projects come from NIH RePORTER, which records the NOFO number every award was made under. GotGrant counts distinct projects and award dollars for FY2022–FY2026. A new NOFO that reissues an older one shows the older NOFO's funding until awards appear under the new number.

How current is this list?

The NOFO list, notices, and funding counts were refreshed from the NIH Guide and NIH RePORTER on October 16, 2026. Open or expired status and next due dates are recalculated daily. NOFOs posted after the refresh appear at the next one, so always confirm details in the NIH Guide before applying.

New to NIH funding? Start with the NIH funding guide or how to find NIH funding opportunities.