NIH Guide + NIH RePORTER
Open NIH NOFOs: Due Dates, Institutes & Funded Projects
Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards
NIH has 380 open notices of funding opportunity. The NIH Guide spreads each one across its own page, participation and due-date notices, and NOSIs. Each page here puts them together, and adds how many projects NIH actually funded under that NOFO.
Open now
349
Accepting applications
Opening soon
31
Posted, open date ahead
Due in 30 days
117
Next due date by Nov 15, 2026
With funding history
305
Funded projects under it or its predecessor
Due in the next 30 days
- PAS-27-028NIDA · R03Science Track Award for Research Transition (START) Program (R03, Clinical Trial Optional)Due Oct 16, 2026 · in 0 days
- PAR-27-074NIAMS · R03Limited Competition: Small Grant Program for Mentored Research Career Development Award Recipients (R03) (Clinical Trials Not Allowed)Due Oct 16, 2026 · in 0 days
- PAR-27-015NIDCR · UG3, UH3Community-Based Participatory Research to Advance Data and Practice Transformation (ADAPT) for Optimizing Oral Health for All (UG3/UH3 Clinical Trial Optional)Due Oct 16, 2026 · in 0 days
- PAR-25-370NHGRI · R03Ethical, Legal and Social Implications (ELSI) Small Research Grant (R03 Clinical Trial Optional)Due Oct 16, 2026 · in 0 days
- PAR-25-091NIDDK · R03Limited Competition: Small Grant Program for NIDDK K01/K08/K23/K25 Recipients (R03 Clinical Trial Optional)Due Oct 16, 2026 · in 0 days
- PAR-25-358NEI · R34NEI Clinical Research Study Planning Grant Program (R34 Clinical Trial Not Allowed)Due Oct 16, 2026 · in 0 days
- PAR-24-329NIDA · R34Development and Testing of Novel Interventions to Improve HIV Prevention, Treatment, and Program Implementation for People Who Use Substances (R34 Clinical Trial Required)Due Oct 16, 2026 · in 0 days
- PAR-25-068NIDDK · R21Pilot Studies of Biological, Behavioral and Social Mechanisms Contributing to HIV Pathogenesis Within the Mission of NIDDK (R21 Clinical Trial Not Allowed)Due Oct 16, 2026 · in 0 days
- PAR-25-357NEI · R21NEI Research Grant for Vision-Related Secondary Data Analysis (R21 Clinical Trial Not Allowed)Due Oct 16, 2026 · in 0 days
- PAR-25-284NIMH · R34Innovative Pilot Mental Health Services Research Not Involving Clinical Trials (R34 Clinical Trial Not Allowed)Due Oct 16, 2026 · in 0 days
107 more in the full list below, sorted by next due date.
Newly posted
- PAR-28-090NIAID · P30Centers for AIDS Research (CFAR) and Developmental Centers for AIDS Research (D-CFAR) (P30 Clinical Trial Not Allowed)Posted Oct 16, 2026
- RFA-LM-28-001NLM · T15NLM Institutional Grants for Research Training in Biomedical Informatics, Data Science, and AI (T15 Independent Clinical Trial Not Allowed)Posted Oct 16, 2026
- PAR-28-091NCCIH · R33Assessing the Feasibility of Incorporating Mechanisms in Multi-site Clinical Trials of Mind and Body Interventions on Whole Person Health Restoration (R33 Clinical Trial Required)Posted Oct 15, 2026
- RFA-AA-28-001NIAAA · P50Specialized Alcohol Research Centers (P50 Clinical trial Optional)Posted Oct 15, 2026
- RFA-CA-28-004NCI · U24Limited Competition: Biospecimen Banks to support NCI National Clinical Trials Network Biospecimen Banks (NCTN Biobanks) and the NCI Early-Phase and Experimental Clinical Trials Biospecimen Bank (EET Biobank) (U24 Clinical Trial Not Allowed)Posted Oct 15, 2026
- RFA-DK-27-122NIDDK · U01Single Source for the Continuation of the Physiology of the Weight Reduced State (POWERS) Study (U01- Clinical Trials Required)Posted Oct 15, 2026
- PA-27-061OD · P01NIH Research Program Projects (Parent P01 Clinical Trial Optional)Posted Oct 14, 2026
- PAR-27-003NIGMS · RM1Collaborative Program Grant for Interdisciplinary Teams (RM1 Clinical Trial Optional)Posted Oct 14, 2026
All NIH NOFOs
Search by NOFO number, title words, institute, or activity code. Filters stay in the address bar, so a filtered list can be bookmarked or shared.
380 NOFOs open or opening soon
| NOFO | Next due | Codes | Funded projects | Expires |
|---|---|---|---|---|
| PAS-27-028 Science Track Award for Research Transition (START) Program (R03, Clinical Trial Optional) PAS · NIDA + 1 more · R03 | Oct 16, 2026 | R03 | 2* | Mar 17, 2029 |
| PAR-27-074 Limited Competition: Small Grant Program for Mentored Research Career Development Award Recipients (R03) (Clinical Trials Not Allowed) PAR · NIAMS + 1 more · R03 | Oct 16, 2026 | R03 | 2* | Jul 17, 2029 |
| PAR-27-015 Community-Based Participatory Research to Advance Data and Practice Transformation (ADAPT) for Optimizing Oral Health for All (UG3/UH3 Clinical Trial Optional) PAR · NIDCR + 5 more · UG3, UH3 | Oct 16, 2026 | UG3, UH3 | — | Nov 17, 2028 |
| PAR-25-370 Ethical, Legal and Social Implications (ELSI) Small Research Grant (R03 Clinical Trial Optional) PAR · NHGRI + 13 more · R03 | Oct 16, 2026 | R03 | 1* | Nov 17, 2026 |
| PAR-25-091 Limited Competition: Small Grant Program for NIDDK K01/K08/K23/K25 Recipients (R03 Clinical Trial Optional) PAR · NIDDK + 1 more · R03 | Oct 16, 2026 | R03 | 36 | Jan 8, 2028 |
| PAR-25-358 NEI Clinical Research Study Planning Grant Program (R34 Clinical Trial Not Allowed) PAR · NEI + 1 more · R34 | Oct 16, 2026 | R34 | 4 | Jan 8, 2028 |
| PAR-24-329 Development and Testing of Novel Interventions to Improve HIV Prevention, Treatment, and Program Implementation for People Who Use Substances (R34 Clinical Trial Required) PAR · NIDA + 1 more · R34 | Oct 16, 2026 | R34 | 6 | Mar 17, 2027 |
| PAR-25-068 Pilot Studies of Biological, Behavioral and Social Mechanisms Contributing to HIV Pathogenesis Within the Mission of NIDDK (R21 Clinical Trial Not Allowed) PAR · NIDDK + 1 more · R21 | Oct 16, 2026 | R21 | 1 | Nov 17, 2027 |
| PAR-25-357 NEI Research Grant for Vision-Related Secondary Data Analysis (R21 Clinical Trial Not Allowed) PAR · NEI + 1 more · R21 | Oct 16, 2026 | R21 | 4 | Oct 17, 2027 |
| PAR-25-284 Innovative Pilot Mental Health Services Research Not Involving Clinical Trials (R34 Clinical Trial Not Allowed) PAR · NIMH + 1 more · R34 | Oct 16, 2026 | R34 | 1 | Jan 8, 2028 |
| PA-25-302 NIH Small Research Grant Program (Parent R03 Clinical Trial Not Allowed) PA · NIH + 14 more · R03 | Oct 16, 2026 | R03 | 130 | Jan 8, 2028 |
| PA-25-304 NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Not Allowed) PA · NIH + 22 more · R21 | Oct 16, 2026 | R21 | 1,216 | Jan 8, 2028 |
| PA-25-306 NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Required) PA · NIH + 17 more · R21 | Oct 16, 2026 | R21 | 57 | Jan 8, 2028 |
| PAR-25-032 NHLBI Clinical Trial Pilot Studies (R34 Clinical Trial Optional) PAR · NHLBI + 1 more · R34 | Oct 16, 2026 | R34 | 20 | Jan 8, 2027 |
| PAR-25-346 Exploratory/Developmental Bioengineering Research Grants (EBRG) (R21 Clinical Trial Not Allowed) PAR · NCI + 1 more · R21 | Oct 16, 2026 | R21 | 18 | Jan 8, 2028 |
| PAR-25-321 Exploratory/Developmental Bioengineering Research Grants (EBRG) (R21 Clinical Trial Optional) PAR · NCI + 1 more · R21 | Oct 16, 2026 | R21 | 3 | Jan 8, 2028 |
| PAR-25-100 Pilot Health Services and Economic Research on the Treatment of Drug, Alcohol, and Tobacco Use Disorders (R34 Clinical Trial Optional) PAR · NIDA + 1 more · R34 | Oct 16, 2026 | R34 | 4 | May 8, 2027 |
| PAR-25-266 Innovative Screening Approaches and Therapies for Screenable Disorders in Newborns (R21 - Clinical Trial Optional) PAR · NICHD + 1 more · R21 | Oct 16, 2026 | R21 | 1 | Nov 17, 2027 |
| PAR-25-159 Prevention and Intervention Approaches for Fetal Alcohol Spectrum Disorders (R34 Clinical Trial Optional) PAR · NIAAA + 1 more · R34 | Oct 16, 2026 | R34 | 1 | Jan 8, 2027 |
| PAR-25-272 New Approaches for Measuring Brain Changes Across Longer Timespans (R21 Clinical Trial Optional) PAR · NIA + 2 more · R21 | Oct 16, 2026 | R21 | 3 | May 8, 2027 |
| PAR-25-288 Navigator Emergency Department Diversion Models for Non-Urgent Mental Health Concerns (R34 Clinical Trial Required) PAR · NIMH + 1 more · R34 | Oct 16, 2026 | R34 | — | Jan 8, 2028 |
| PAR-25-282 Mood and Psychosis Symptoms during the Menopause Transition (R21 Clinical Trial Optional) PAR · NIMH + 1 more · R21 | Oct 16, 2026 | R21 | — | Jan 8, 2028 |
| PAR-25-291 Utilizing Invasive Recording and Stimulating Opportunities in Humans to Advance Neural Circuitry Understanding of Mental Health Disorders (R21 Clinical Trial Optional) PAR · NIMH + 1 more · R21 | Oct 16, 2026 | R21 | 2* | Jan 8, 2028 |
| PAR-25-286 Neuromodulation/Neurostimulation Device Development for Mental Health Applications (R21 Clinical Trial Not Allowed) PAR · NIMH + 1 more · R21 | Oct 16, 2026 | R21 | 1 | Jan 8, 2028 |
| PA-25-125 NICHD Small Research Grant Program (R03 Clinical Trial Required) PA · NICHD + 1 more · R03 | Oct 16, 2026 | R03 | 8* | Jan 8, 2028 |
| PAR-25-070 Mechanisms that Impact Cancer Risk with Use of Incretin Mimetics (R21 Clinical Trial Not Allowed) PAR · NCI + 1 more · R21 | Oct 16, 2026 | R21 | 2 | Jan 8, 2027 |
| PAR-25-105 NIDCR Small Grant Program for New Investigators (R03 Clinical Trial Not Allowed) PAR · NIDCR + 1 more · R03 | Oct 16, 2026 | R03 | 24 | Jan 8, 2028 |
| PAR-25-113 Advancement and Innovation in Measurement of Language Development and Predictors (R21 Clinical Trial Not Allowed) PAR · NICHD + 1 more · R21 | Oct 16, 2026 | R21 | — | Sep 8, 2027 |
| PAR-25-124 NCMRR Early Career Research Award (R03 Clinical Trial Optional) PAR · NICHD + 1 more · R03 | Oct 16, 2026 | R03 | 10 | Jan 8, 2028 |
| PAR-25-244 Basic Research in Cancer Health Disparities (R21 Clinical Trial Not Allowed) PAR · NCI + 1 more · R21 | Oct 16, 2026 | R21 | 3 | Nov 17, 2027 |
| PAR-25-256 Developing novel theory and methods for understanding the genetic architecture of complex human traits (R21 Clinical Trial Not Allowed) PAR · NHGRI + 1 more · R21 | Oct 16, 2026 | R21 | 1* | Jan 8, 2027 |
| PAR-25-273 Development of Animal Models and Related Biological Materials for Research (R21 Clinical Trial Not Allowed) PAR · ORIP + 1 more · R21 | Oct 16, 2026 | R21 | 11 | Jan 8, 2028 |
| PA-25-253 Exploratory Grants in Cancer Control (R21 Clinical Trial Optional) PA · NCI + 1 more · R21 | Oct 16, 2026 | R21 | 12 | Sep 8, 2028 |
| PAR-25-077 CCRP Initiative: NIH Countermeasures Against Chemical Threats (CounterACT) Basic Research on Chemical Threats that Affect the Nervous System (R01 Clinical Trial Not Allowed) PAR · NINDS + 1 more · R01 | Oct 16, 2026 | R01 | 4 | Oct 17, 2026 |
| PAR-25-143 Dissemination and Implementation Research in Health (R21 Clinical Trial Optional) PAR · NCI + 19 more · R21 | Oct 16, 2026 | R21 | 10 | Jan 8, 2028 |
| PAR-25-233 Dissemination and Implementation Research in Health (R03 Clinical Trial Not Allowed) PAR · NCI + 13 more · R03 | Oct 16, 2026 | R03 | 3* | Jan 8, 2028 |
| PAR-25-122 Pilot Projects Investigating Understudied Proteins Associated with Rare Diseases (R03 Clinical Trial Not Allowed) PAR · NCATS + 5 more · R03 | Oct 16, 2026 | R03 | 25 | Nov 17, 2027 |
| PA-25-093 Limited Competition: CCRP Initiative: Promoting a Basic Understanding of Chemical Threats to Skin (R34 Clinical Trial Not Allowed) PA · NIAMS + 1 more · R34 | Oct 16, 2026 | R34 | 2 | Jan 8, 2028 |
| PAR-25-044 Mechanisms that Impact Cancer Risk after Bariatric Surgery (R21 Clinical Trial Not Allowed) PAR · NCI + 1 more · R21 | Oct 16, 2026 | R21 | — | Jan 8, 2028 |
| RFA-RM-27-012 PRIMED-AI: Data-to-Model Academic-Industrial Partnerships (D2M-AIP) for Precision Medicine with AI: Integrating Imaging with Multimodal Data (UG3/UH3 Clinical Trial Optional) RFA · RMOD + 2 more · UG3, UH3 | Oct 19, 2026 | UG3, UH3 | — | Oct 20, 2026 |
| RFA-RM-27-013 Model-to-Clinic (M2C) for Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) (UG3/UH3, Clinical Trial Optional) RFA · RMOD + 2 more · UG3, UH3 | Oct 19, 2026 | UG3, UH3 | — | Oct 20, 2026 |
| RFA-CA-27-019 Early-Stage Development of Informatics Technologies for Cancer Research and Management (U01 Clinical Trial Optional) RFA · NCI + 1 more · U01 | Oct 19, 2026 | U01 | 6* | Oct 20, 2027 |
| RFA-CA-27-020 Advanced Development of Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional) RFA · NCI + 1 more · U24 | Oct 19, 2026 | U24 | 6* | Oct 20, 2026 |
| RFA-CA-27-021 Sustained Support for Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional) RFA · NCI + 1 more · U24 | Oct 19, 2026 | U24 | 1* | Oct 20, 2026 |
| RFA-DE-27-001 Community Engagement Evaluation and Data Coordination (CEED) Hub to Advance Data and Practice Transformation for Optimizing Oral Health for All (U01, Clinical Trial Not Allowed) RFA · NIDCR + 4 more · U01 | Oct 19, 2026 | U01 | — | Oct 20, 2026 |
| PAR-25-343 NIDCD Cooperative Agreement for Clinical Trials in Communication Disorders (U01 - Clinical Trial Required) PAR · NIDCD + 1 more · U01 | Oct 19, 2026 | U01 | 2 | Oct 19, 2027 |
| PAR-25-155 Limited Competition: Small Grant Program for the NCATS Clinical and Translational Science Award (CTSA) Program (R03 Clinical Trial Optional) PAR · NCATS + 1 more · R03 | Oct 19, 2026 | R03 | 5 | Oct 20, 2026 |
| PAR-25-296 Limited Competition: Clinical and Translational Science Award (CTSA) Program: Collaborative and Innovative Acceleration Award (UG3/UH3 Clinical Trial Optional) PAR · NCATS + 10 more · UG3, UH3 | Oct 19, 2026 | UG3, UH3 | 3 | Oct 20, 2027 |
| PAR-25-158 Prevention and Intervention Approaches for Fetal Alcohol Spectrum Disorders (R61/R33 Clinical Trial Optional) PAR · NIAAA + 1 more · R61, R33 | Oct 19, 2026 | R61, R33 | 3 | Nov 18, 2026 |
| PAR-25-226 Seamless Early-Stage Clinical Drug Development (Phase 1 to 2a) for Novel therapeutic Agents for the Spectrum of Alzheimer's Disease (AD) and AD-related Dementias (ADRD) (UG3/UH3 Clinical Trial Required) PAR · NIA + 1 more · UG3, UH3 | Oct 19, 2026 | UG3, UH3 | 6 | Nov 20, 2026 |
* Funded projects under the NOFO it reissues; the new number has no awards yet.
By lead institute
- NCI · National Cancer Institute51
- NIH36
- NIMH · National Institute of Mental Health32
- NIGMS · National Institute of General Medical Sciences23
- NIDA · National Institute on Drug Abuse22
- NINDS · National Institute of Neurological Disorders and Stroke22
- NHLBI · National Heart, Lung, and Blood Institute19
- OD · NIH Office of the Director18
- NIA · National Institute on Aging14
- NICHD · Eunice Kennedy Shriver National Institute of Child Health and Human Development14
- NHGRI · National Human Genome Research Institute13
- NIDDK · National Institute of Diabetes and Digestive and Kidney Diseases13
- NCCIH · National Center for Complementary and Integrative Health12
- NIDCD · National Institute on Deafness and Other Communication Disorders12
- NCATS · National Center for Advancing Translational Sciences11
- NIAID · National Institute of Allergy and Infectious Diseases11
- NIDCR · National Institute of Dental and Craniofacial Research11
- NIAMS · National Institute of Arthritis and Musculoskeletal and Skin Diseases7
- RMOD7
- NIMHD · National Institute on Minority Health and Health Disparities5
NIH NOFO questions
What is an NIH NOFO?
A Notice of Funding Opportunity (NOFO, formerly FOA) is the announcement NIH publishes in the NIH Guide for Grants and Contracts to invite applications. It sets the activity code, participating institutes, eligibility, budget, due dates, and review criteria. Every NIH grant application is submitted under a NOFO number such as PA-25-301.
What is the difference between a PA, PAR, and RFA?
A PA (Program Announcement) is an ongoing invitation, usually with standard due dates; parent announcements such as the parent R01 are PAs. A PAR is a program announcement with special receipt, referral, or review, often with its own due dates and a dedicated review panel. An RFA (Request for Applications) is a one-time solicitation with set-aside funds and usually a single due date.
Why does one NOFO have so many notices?
After posting, NIH changes a NOFO through separate notices in the NIH Guide: another institute joining (a participation notice), due-date changes, early expiration, or policy updates. Notices of Special Interest (NOSIs) are attached separately to signal topics an institute wants to fund through it. Each GotGrant NOFO page lists the related notices and active NOSIs together.
How are funded projects counted?
Funded projects come from NIH RePORTER, which records the NOFO number every award was made under. GotGrant counts distinct projects and award dollars for FY2022–FY2026. A new NOFO that reissues an older one shows the older NOFO's funding until awards appear under the new number.
How current is this list?
The NOFO list, notices, and funding counts were refreshed from the NIH Guide and NIH RePORTER on October 16, 2026. Open or expired status and next due dates are recalculated daily. NOFOs posted after the refresh appear at the next one, so always confirm details in the NIH Guide before applying.
New to NIH funding? Start with the NIH funding guide or how to find NIH funding opportunities.