NIH RFA · NIDA · R01
RFA-DA-26-055: Accelerating the Pace of Substance Use Research Using Existing Data (R01 Clinical Trial Not Allowed)
Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards
The purpose of this Notice of Opportunity Announcement (NOFO) is to invite applications proposing the innovative analysis of existing social science, behavioral, administrative, and neuroimaging data to study the etiology and epidemiology of drug using behaviors (defined as alcohol, tobacco, prescription and other drug) and related disorders, prevention of drug use and HIV, and health service utilization. This FOA encourages the analyses of public use and other extant community-based or clinical datasets to their full potential in order to increase our knowledge of etiology, trajectories of drug using behaviors and their consequences including morbidity and mortality, risk and resilience in…
- NOFO number
- RFA-DA-26-055
- Type
- RFA
- Activity code
- R01
- Primary institute
- NIDA · National Institute on Drug Abuse
- Clinical trials
- Not Allowed
- Posted
- Dec 5, 2024
- Opens
- Jun 17, 2025
- Expires
- Dec 4, 2027
RFA-DA-26-055 due dates
3 application due dates remain before the NOFO expires. Dates marked * are NIH standard due dates. Check the related notices below for changes NIH made after posting.
| Application Due Date(s) | Renewal / Resubmission / Revision (as allowed) | AIDS - New/Renewal/Resubmission/Revision, as allowed | Scientific Merit Review | Advisory Council Review | Earliest Start Date |
|---|---|---|---|---|---|
| July 17, 2025 | July 17, 2025 | July 17, 2025 | October 2025 | January 2026 | April 2026 |
| December 03, 2025 | December 03, 2025 | December 03, 2025 | March 2026 | May 2026 | July 2026 |
| July 17, 2026 | July 17, 2026 | Not Applicable | October 2026 | January 2027 | April 2027 |
| December 03, 2026 | December 03, 2026 | Not Applicable | March 2027 | May 2027 | July 2027 |
| July 15, 2027 | July 15, 2027 | Not Applicable | October 2027 | January 2028 | April 2028 |
| December 03, 2027 | December 03, 2027 | Not Applicable | March 2028 | May 2028 | July 2028 |
Projects funded under RFA-DA-26-055
NIH RePORTER lists 10 projects funded under RFA-DA-26-055 in FY2022–FY2026, with $6.8M in award dollars. Counts include each project's later non-competing years, which keep the original NOFO number.
Projects funded
10
Distinct projects, FY2022–FY2026
New awards
9
Type 1 (new project) award records
NIH funding
$6.8M
Award dollars under RFA-DA-26-055, FY2022–FY2026
Funding by fiscal year
| Fiscal year | Award records | New awards | Funding |
|---|---|---|---|
| FY2022 | 0 | 0 | $0 |
| FY2023 | 0 | 0 | $0 |
| FY2024 | 0 | 0 | $0 |
| FY2025 | 0 | 0 | $0 |
| FY2026 | 10 | 9 | $6.8M |
Institutions with the most funding
- Boston Medical Center$1.7M · 2 projects
- University of California, San Francisco$1.1M · 1 project
- McLean Hospital$982K · 1 project
- Emory University$748K · 1 project
- Boston University Medical Campus$733K · 1 project
- University of Kentucky$549K · 1 project
- Rutgers Biomedical and Health Sciences$515K · 1 project
- Boston College$373K · 1 project
Funding institutes
- NIDA$6.8M · 10
Activity codes funded
- R0110 records
Most recent new awards
- Neurobiological Correlates of Susceptibility, Resilience, and Recovery to Substance Abuse in Participants with Childhood Maltreatment (opens NIH RePORTER)
McLean Hospital · 1R01DA065290-01A1 · NIDA · Notice Sep 3, 2026
$982KR01
- Opioid Use Disorder County Area Prevalence Through Use of Recapture Estimates (OUD CAPTURE) (opens NIH RePORTER)
University of Kentucky · 1R01DA064086-01A1 · NIDA · Notice Aug 31, 2026
$549KR01
- Pre-Release Medicaid Effects on Youth Experiences Related to Substances (PRiME YEaRS) (opens NIH RePORTER)
Boston Medical Center · 1R01DA067138-01 · NIDA · Notice Aug 26, 2026
$870KR01
- Fostering new lessons from collaborations to study stimulants, HIV, and brain aging in existing cohorts with key data (opens NIH RePORTER)
University of California, San Francisco · 1R01DA066684-01 · NIDA · Notice Jul 17, 2026
$1.1MR01
- Post-overdose treatment gaps and prevention opportunities in a national population of high-risk youth (opens NIH RePORTER)
Rutgers Biomedical and Health Sciences · 1R01DA066723-01 · NIDA · Notice Jun 30, 2026
$515KR01
- Evaluating the effects of recreational cannabis policies on prenatal cannabis use and maternal and child health outcomes for real-world impact (opens NIH RePORTER)
Boston College · 1R01DA066717-01 · NIDA · Notice Jun 10, 2026
$373KR01
What its predecessor RFA-DA-22-037 funded
RFA-DA-26-055 reissues RFA-DA-22-037. Its funding history is the best guide to who wins under this program: 40 projects and $74.8M in FY2022–FY2026.
Projects funded
40
Distinct projects, FY2022–FY2026
New awards
35
Type 1 (new project) award records
NIH funding
$74.8M
Award dollars under RFA-DA-22-037, FY2022–FY2026
Funding by fiscal year
| Fiscal year | Award records | New awards | Funding |
|---|---|---|---|
| FY2022 | 6 | 6 | $3.3M |
| FY2023 | 17 | 10 | $10.2M |
| FY2024 | 30 | 10 | $18.1M |
| FY2025 | 33 | 8 | $21.1M |
| FY2026 | 35 | 1 | $22.1M |
Institutions with the most funding
- New York University School of Medicine$5.0M · 2 projects
- Rutgers Biomedical and Health Sciences$4.7M · 2 projects
- Columbia University Health Sciences$3.8M · 3 projects
- Boston Medical Center$3.4M · 1 project
- University of Michigan at Ann Arbor$3.3M · 2 projects
- McLean Hospital$3.0M · 1 project
- Massachusetts General Hospital$2.8M · 1 project
- Pennsylvania State University, the$2.7M · 1 project
Funding institutes
- NIDA$74.8M · 121
Activity codes funded
- R01121 records
Most recent new awards
- Using data fusion to inform personalized protocols to optimally treat opioid use disorder (opens NIH RePORTER)
Columbia University Health Sciences · 1R01DA063973-01 · NIDA · Notice May 18, 2026
$778KR01
- The Impact of Cannabis Use Disorder and its Treatment on Opioid-related Health Consequences: A Longitudinal Study of VA Patients (opens NIH RePORTER)
Columbia University Health Sciences · 1R01DA064130-01 · NIDA · Notice Sep 12, 2025
$745KR01
- Optimizing methadone treatment strategies for opioid use disorder in the era of fentanyl (opens NIH RePORTER)
Brown University · 1R01DA062186-01A1 · NIDA · Notice Aug 22, 2025
$915KR01
- Examining the Effects of ADHD Medications on Substance-Related Morbidity and Mortality Among Young People (opens NIH RePORTER)
Trustees of Indiana University · 1R01DA062181-01A1 · NIDA · Notice Aug 15, 2025
$780KR01
- Longitudinal pathways between adolescent social media use and substance use: Informing evidence-based guidance (opens NIH RePORTER)
University of California, San Francisco · 1R01DA064134-01 · NIDA · Notice Jul 17, 2025
$703KR01
- Vulnerability to Substance Use: Transitions and Trajectories in ABCD Youth with Validation Using Longitudinal Twin Family Samples (opens NIH RePORTER)
Virginia Commonwealth University · 1R01DA063061-01 · NIDA · Notice Jun 30, 2025
$721KR01
FY2026 closed on September 30, 2026, but NIH keeps posting that year's awards to RePORTER for several weeks. FY2026 figures reflect records available on October 16, 2026 and may rise slightly at the next refresh.
Participating institutes
2 NIH institutes and offices take applications under RFA-DA-26-055. Contact the program officer at the institute that fits your research before applying.
- NIDA · National Institute on Drug Abuse
- none
Related notices
Jan 28, 2026 · NOT-OD-26-029
NIH Removing AIDS Application Due Dates from NOFOs.
Mar 31, 2025 · NOT-OD-24-084
This funding opportunity was updated to align with agency priorities. Carefully reread the full funding opportunity and make any needed adjustments to your application prior to submission.April 4, 2024 - Overview of Grant Application and Review Changes for Due Dates on or after January 25,…
Aug 31, 2022 · NOT-OD-22-198
Implementation Changes for Genomic Data Sharing Plans Included with Applications Due on or after January 25, 2023. See Notice NOT-OD-22-198.
Aug 5, 2022 · NOT-OD-22-189
Implementation Details for the NIH Data Management and Sharing Policy.
Notices of Special Interest (NOSIs)
NIH has attached 1 NOSI to RFA-DA-26-055; none are active now. A NOSI flags a topic an institute wants to fund through this NOFO.
Award terms
- Application types allowed
- NewRenewalResubmissionRevision The OER Glossary and the How to Apply Application Guide provide details on these application types. Only those application types listed here are allowed for this NOFO.
- Award budget
- Application budgets are not limited but need to reflect the actual needs of the proposed project.
- Project period
- The scope of the proposed project should determine the project period. The maximum project period is 5 years NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO.
- Funds available and number of awards
- NIDA intends to commit 2 million in FY 2026 to award 2-4 applications, with an additional 2 million for 2-4 applications focused on HIV research, in response to this and the companion R21 RFA RFA-DA-26-056.
Summarized from the NOFO text; the full NOFO governs eligibility, budget, and review.
Related NOFOs
- Reissue of RFA-DA-22-037.
- Companion NOFOs: RFA-DA-26-056.
Other open NOFOs for R01
- PAR-25-379Intervention Research to Improve Native American Health (R01 Clinical Trial Optional)NIDA · next due Oct 21, 2026
- RFA-DA-26-034Chemical Countermeasures Research Program (CCRP) Initiative: Basic Research on The Deleterious Effects of Acute Exposure to Ultra-Potent Synthetic (UPS) Opioids (R01 Clinical Trial Not Allowed)NIDA · next due Nov 18, 2026
- RFA-DA-27-004BRAIN Initiative: Theories, Models and Methods for Analysis of Complex Data from the Brain (R01 Clinical Trial Not Allowed)NIDA · next due Oct 6, 2027
- RFA-DA-25-024High Priority HIV and Substance Use Research (R01 Clinical Trial Optional)NIDA
- PAR-25-371Ethical, Legal and Social Implications (ELSI) Research (R01 Clinical Trial Optional)NHGRI · next due Oct 20, 2026
- PAR-27-081Discovery of in vivo Chemical Probes for the Nervous System (R01 Clinical Trial Not Allowed)NIA · next due Feb 5, 2027
About this page
GotGrant gathers the NOFO, its participation and change notices, and its NOSIs from the NIH Guide for Grants and Contracts, and counts funded projects from NIH RePORTER by the opportunity number each award was made under. Data refreshed October 16, 2026; the NIH Guide is the authoritative source. See our data methodology.