NIH PAR · NIDA · R01

PAR-25-379: Intervention Research to Improve Native American Health (R01 Clinical Trial Optional)

Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards

Open for applicationsNext due date: Oct 21, 2026Expires Jan 8, 2027

The purpose of this funding opportunity announcement (FOA) is to support research on interventions to improve health in Native American (NA) populations. This includes 1) etiologic research, where there is a significant gap in knowledge, that will directly inform intervention development or adaptations, 2) research that develops, adapts, or tests the efficacy or effectiveness of health promotion and disease prevention interventions, 3) research that tests culturally informed treatment or recovery interventions and 4) where a sufficient body of knowledge on intervention efficacy exists, research on dissemination and implementation that develops and tests strategies to overcome barriers to…

Full NOFO in the NIH Guide

NOFO number
PAR-25-379
Type
PAR
Activity code
R01
Primary institute
NIDA · National Institute on Drug Abuse
Clinical trials
Optional
Posted
Jan 21, 2025
Opens
Sep 21, 2025
Expires
Jan 8, 2027

PAR-25-379 due dates

1 application due date remains before the NOFO expires. Dates marked * are NIH standard due dates. Check the related notices below for changes NIH made after posting.

Application due dates and review cycles for PAR-25-379
Application Due Date(s)Renewal / Resubmission / Revision (as allowed)AIDS - New/Renewal/Resubmission/Revision, as allowedScientific Merit ReviewAdvisory Council ReviewEarliest Start Date
October 21, 2025October 21, 2025January 07, 2026 *March 2026May 2026July 2026
October 21, 2026October 21, 2026Not ApplicableMarch 2027May 2027July 2027

Projects funded under PAR-25-379

NIH RePORTER lists 5 projects funded under PAR-25-379 in FY2022–FY2026, with $5.9M in award dollars. Counts include each project's later non-competing years, which keep the original NOFO number.

Projects funded

5

Distinct projects, FY2022–FY2026

New awards

5

Type 1 (new project) award records

NIH funding

$5.9M

Award dollars under PAR-25-379, FY2022–FY2026

Funding by fiscal year

Award records, new awards, and funding by fiscal year under PAR-25-379
Fiscal yearAward recordsNew awardsFunding
FY202200$0
FY202300$0
FY202400$0
FY202500$0
FY202655$5.9M

Institutions with the most funding

  1. Oregon Health & Science University$3.1M · 1 project
  2. University of Hawaii at Manoa$1.4M · 2 projects
  3. University of Oklahoma Hlth Sciences Ctr$716K · 1 project
  4. Medical College of Wisconsin$706K · 1 project

Funding institutes

  • NIMHD$5.2M · 4
  • NIEHS$706K · 1

Activity codes funded

Most recent new awards

What its predecessor PAR-23-298 funded

PAR-25-379 reissues PAR-23-298. Its funding history is the best guide to who wins under this program: 6 projects and $12.6M in FY2022–FY2026.

Projects funded

6

Distinct projects, FY2022–FY2026

New awards

5

Type 1 (new project) award records

NIH funding

$12.6M

Award dollars under PAR-23-298, FY2022–FY2026

Funding by fiscal year

Award records, new awards, and funding by fiscal year under PAR-23-298
Fiscal yearAward recordsNew awardsFunding
FY202200$0
FY202300$0
FY202400$0
FY202554$9.3M
FY202631$3.3M

Institutions with the most funding

  1. Johns Hopkins University$6.4M · 3 projects
  2. Montana State University - Bozeman$3.5M · 1 project
  3. University of Alaska Fairbanks$1.4M · 1 project
  4. Henry Ford Health + Michigan State University Health Sciences$1.4M · 1 project

Funding institutes

  • NIMHD$6.6M · 2
  • NINR$3.2M · 3
  • NHLBI$1.4M · 1
  • NICHD$1.4M · 2

Activity codes funded

Most recent new awards

FY2026 closed on September 30, 2026, but NIH keeps posting that year's awards to RePORTER for several weeks. FY2026 figures reflect records available on October 16, 2026 and may rise slightly at the next refresh.

Participating institutes

21 NIH institutes and offices take applications under PAR-25-379. Contact the program officer at the institute that fits your research before applying.

  • NIDA · National Institute on Drug Abuse
  • NHLBI · National Heart, Lung, and Blood Institute
  • NIA · National Institute on Aging
  • NIAAA · National Institute on Alcohol Abuse and Alcoholism
  • NIAID · National Institute of Allergy and Infectious Diseases
  • NIBIB · National Institute of Biomedical Imaging and Bioengineering
  • NICHD · Eunice Kennedy Shriver National Institute of Child Health and Human Development
  • NIDCD · National Institute on Deafness and Other Communication Disorders
  • NIDCR · National Institute of Dental and Craniofacial Research
  • NIDDK · National Institute of Diabetes and Digestive and Kidney Diseases
  • NIEHS · National Institute of Environmental Health Sciences
  • NIMH · National Institute of Mental Health
  • NINR · National Institute of Nursing Research
  • NIMHD · National Institute on Minority Health and Health Disparities
  • NIAMS · National Institute of Arthritis and Musculoskeletal and Skin Diseases
  • NLM · National Library of Medicine
  • NCI · National Cancer Institute
  • ODP
  • OBSSR
  • ORWH
  • THRO

Related notices

  1. Jun 12, 2025 · NOT-AR-25-017

    Notice of NIAMS Participation in PAR-25-379, Intervention Research to Improve Native American Health R01 Clinical Trial Optional). See Notice NOT-AR-25-017.April 4, 2024 - Overview of Grant Application and Review Changes for Due Dates on or after January 25, 2025. See Notice…

  2. Aug 31, 2022 · NOT-OD-22-198

    Implementation Changes for Genomic Data Sharing Plans Included with Applications Due on or after January 25, 2023. See Notice NOT-OD-22-198.

  3. Aug 5, 2022 · NOT-OD-22-189

    Implementation Details for the NIH Data Management and Sharing Policy.

Award terms

Application types allowed
NewRenewalResubmissionRevision The OER Glossary and the How to Apply Application Guide provide details on these application types. Only those application types listed here are allowed for this NOFO.
Award budget
Application budgets are not limited but need to reflect the actual needs of the proposed project. Applicants requesting 500,000 or more in direct costs in any year excluding consortium F & A) should see instructions in Section IV below.
Project period
The scope of the proposed project should determine the project period. The total project period may not exceed 5 years. NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO.
Funds available and number of awards
The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications.

Summarized from the NOFO text; the full NOFO governs eligibility, budget, and review.

Related NOFOs

  • Reissue of PAR-23-298.
  • Companion NOFOs: PAR-25-378.

Other open NOFOs for R01

Browse all open NIH NOFOs

About this page

GotGrant gathers the NOFO, its participation and change notices, and its NOSIs from the NIH Guide for Grants and Contracts, and counts funded projects from NIH RePORTER by the opportunity number each award was made under. Data refreshed October 16, 2026; the NIH Guide is the authoritative source. See our data methodology.

Find who wins under this NOFO

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