NIH PAR · NCI · P30

PAR-25-444: Cancer Center Support Grants (CCSGs) for NCI-designated Cancer Centers (P30 Clinical Trial Optional)

Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards

Open for applicationsNext due date: Jan 25, 2027Expires Sep 26, 2028

This Notice of Funding Opportunity (NOFO) invites applications for P30 Cancer Center Support Grants (CCSGs) to support NCI-Designated Cancer Centers. CCSGs support three types of Cancer Centers: 1) Comprehensive Cancer Centers, which demonstrate reasonable depth and breadth of research activities in each of three major areas: basic laboratory; clinical; and prevention, control and population-based research, and which have substantial transdisciplinary research that bridges these scientific areas; and 2) Clinical Cancer Centers, which are primarily focused on basic laboratory; clinical; and prevention, cancer control, and population-based research; or some combination of these areas, and 3)…

Full NOFO in the NIH Guide Apply on Grants.gov

NOFO number
PAR-25-444
Type
PAR
Activity code
P30
Primary institute
NCI · National Cancer Institute
Clinical trials
Optional
Posted
Nov 26, 2025
Opens
Dec 1, 2025
Expires
Sep 26, 2028

PAR-25-444 due dates

6 application due dates remain before the NOFO expires. Dates marked * are NIH standard due dates. Check the related notices below for changes NIH made after posting.

Application due dates and review cycles for PAR-25-444
NewRenewal / Resubmission / Revision (as allowed)AIDS - New/Renewal/Resubmission/Revision, as allowedScientific Merit ReviewAdvisory Council ReviewEarliest Start Date
January 25, 2026 *January 25, 2026 *Not ApplicableJuly 2026October 2026December 2026
May 25, 2026 *May 25, 2026 *Not ApplicableNovember 2026January 2027April 2027
September 25, 2026 *September 25, 2026 *Not ApplicableMarch 2027May 2027July 2027
January 25, 2027 *January 25, 2027 *Not ApplicableJuly 2027October 2027December 2027
May 25, 2027 *May 25, 2027 *Not ApplicableNovember 2027January 2028April 2028
September 25, 2027 *September 25, 2027 *Not ApplicableMarch 2028May 2028July 2028
January 25, 2028 *January 25, 2028 *Not ApplicableJuly 2028October 2028December 2028
May 25, 2028 *May 25, 2028 *Not ApplicableNovember 2028January 2029April 2029
September 25, 2028 *September 25, 2028 *Not ApplicableMarch 2029May 2029July 2029

What its predecessor PAR-21-321 funded

PAR-25-444 reissues PAR-21-321. Until awards appear under the new number, its funding history is the best guide to who wins under this program: 49 projects and $491.4M in FY2022–FY2026.

Projects funded

49

Distinct projects, FY2022–FY2026

New awards

3

Type 1 (new project) award records

NIH funding

$491.4M

Award dollars under PAR-21-321, FY2022–FY2026

Funding by fiscal year

Award records, new awards, and funding by fiscal year under PAR-21-321
Fiscal yearAward recordsNew awardsFunding
FY202200$0
FY2023171$42.0M
FY2024320$86.3M
FY2025491$151.1M
FY2026491$212.0M

Institutions with the most funding

  1. University of California, San Francisco$32.9M · 1 project
  2. University of Michigan at Ann Arbor$29.2M · 1 project
  3. Fred Hutchinson Cancer Center$23.0M · 1 project
  4. University of Wisconsin-Madison$21.9M · 1 project
  5. Albert Einstein College of Medicine$16.0M · 1 project
  6. Beckman Research Institute/City of Hope$15.9M · 1 project
  7. Yale University$14.5M · 1 project
  8. University of Chicago$13.6M · 1 project

Funding institutes

  • NCI$491.4M · 147

Activity codes funded

Most recent new awards

FY2026 closed on September 30, 2026, but NIH keeps posting that year's awards to RePORTER for several weeks. FY2026 figures reflect records available on October 16, 2026 and may rise slightly at the next refresh.

Participating institutes

2 NIH institutes and offices take applications under PAR-25-444. Contact the program officer at the institute that fits your research before applying.

  • NCI · National Cancer Institute
  • none

Related notices

NIH lists no related notices for PAR-25-444 yet.

Award terms

Application types allowed
New Renewal Resubmission Revision The OER Glossary and the How to Apply - Application Guide provides details on these application types. Only those application types listed here are allowed for this NOFO.
Award budget
New Type 1) applications: Budget should not exceed 1.2 million Basic Cancer Center), 1.4 million Clinical Cancer Center), 1.5 million Comprehensive Cancer Center) in direct costs per year for the project period.Renewal Type 2) applications: Application budgets are not limited but need to reflect the actual needs of the proposed project.
Project period
5 years NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO.
Funds available and number of awards
The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications.

Summarized from the NOFO text; the full NOFO governs eligibility, budget, and review.

Related NOFOs

  • Reissue of PAR-21-321.

Other open NOFOs for P30

Browse all open NIH NOFOs

About this page

GotGrant gathers the NOFO, its participation and change notices, and its NOSIs from the NIH Guide for Grants and Contracts, and counts funded projects from NIH RePORTER by the opportunity number each award was made under. Data refreshed October 16, 2026; the NIH Guide is the authoritative source. See our data methodology.

Find who wins under this NOFO

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