NIH PAR · NLM · R01

PAR-25-131: Computational Approaches to Curation at Scale for Biomedical Research Assets (R01 Clinical Trial Not Allowed)

Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards

Open for applicationsNext due date: Jan 15, 2027Expires Apr 16, 2027

NLM wishes to accelerate access to, and availability of, secure, complete datasets and computational models that can serve as the basis for transformative biomedical discoveries. Innovative at-scale computational approaches that increase the speed and scope of curation processes are needed for data mining and knowledge discovery from growing quantities of biomedical data being produced from ongoing data science advances.

Full NOFO in the NIH Guide Apply on Grants.gov

NOFO number
PAR-25-131
Type
PAR
Activity code
R01
Primary institute
NLM · National Library of Medicine
Clinical trials
Not Allowed
Posted
Oct 29, 2024
Opens
Dec 27, 2024
Expires
Apr 16, 2027

PAR-25-131 due dates

1 application due date remains before the NOFO expires. Dates marked * are NIH standard due dates. Check the related notices below for changes NIH made after posting.

Application due dates and review cycles for PAR-25-131
Application Due Date(s)Renewal / Resubmission / Revision (as allowed)AIDS - New/Renewal/Resubmission/Revision, as allowedScientific Merit ReviewAdvisory Council ReviewEarliest Start Date
January 28, 2025February 24, 2025April 25, 2025July 2025October 2025December 2025
May 15, 2025June 13, 2025August 15, 2025November 2025January 2026April 2026
September 15, 2025October 15, 2025December 15, 2025March 2026May 2026July 2026
January 15, 2026February 13, 2026April 15, 2026July 2026October 2026December 2026
May 15, 2026June 15, 2026Not ApplicableNovember 2026January 2027April 2027
September 15, 2026October 15, 2026Not ApplicableMarch 2027May 2027July 2027
January 15, 2027February 17, 2027Not ApplicableJuly 2027October 2027December 2027

Projects funded under PAR-25-131

NIH RePORTER lists 2 projects funded under PAR-25-131 in FY2022–FY2026, with $360K in award dollars. Counts include each project's later non-competing years, which keep the original NOFO number.

Projects funded

2

Distinct projects, FY2022–FY2026

New awards

1

Type 1 (new project) award records

NIH funding

$360K

Award dollars under PAR-25-131, FY2022–FY2026

Funding by fiscal year

Award records, new awards, and funding by fiscal year under PAR-25-131
Fiscal yearAward recordsNew awardsFunding
FY202200$0
FY202300$0
FY202400$0
FY202500$0
FY202621$360K

Institutions with the most funding

  1. University of Chicago$360K · 1 project

Funding institutes

  • NLM$360K · 2

Activity codes funded

What its predecessor PAR-20-304 funded

PAR-25-131 reissues PAR-20-304. Its funding history is the best guide to who wins under this program: 9 projects and $10.1M in FY2022–FY2026.

Projects funded

9

Distinct projects, FY2022–FY2026

New awards

8

Type 1 (new project) award records

NIH funding

$10.1M

Award dollars under PAR-20-304, FY2022–FY2026

Funding by fiscal year

Award records, new awards, and funding by fiscal year under PAR-20-304
Fiscal yearAward recordsNew awardsFunding
FY202232$1.1M
FY202363$2.0M
FY202482$2.5M
FY202581$3.5M
FY202630$1.0M

Institutions with the most funding

  1. University of Chicago$1.4M · 1 project
  2. Emory University$1.4M · 1 project
  3. Stanford University$1.3M · 1 project
  4. University of Virginia$1.3M · 1 project

Funding institutes

  • NLM$10.1M · 28

Activity codes funded

FY2026 closed on September 30, 2026, but NIH keeps posting that year's awards to RePORTER for several weeks. FY2026 figures reflect records available on October 16, 2026 and may rise slightly at the next refresh.

Participating institutes

2 NIH institutes and offices take applications under PAR-25-131. Contact the program officer at the institute that fits your research before applying.

  • NLM · National Library of Medicine
  • none

Related notices

  1. May 14, 2025 · NOT-LM-25-001

    Notice of Change to Advisory Council Review for PAR-25-131.

  2. Mar 31, 2025 · NOT-OD-24-084

    This funding opportunity was updated to align with agency priorities. Carefully reread the full funding opportunity and make any needed adjustments to your application prior to submission.April 4, 2024 - Overview of Grant Application and Review Changes for Due Dates on or after January 25,…

  3. Aug 31, 2022 · NOT-OD-22-198

    Implementation Changes for Genomic Data Sharing Plans Included with Applications Due on or after January 25, 2023. See Notice NOT-OD-22-198.

  4. Aug 5, 2022 · NOT-OD-22-189

    Implementation Details for the NIH Data Management and Sharing Policy. See Notice NOT-OD-22-189.

Award terms

Application types allowed
NewRenewalResubmission The OER Glossary and the How to Apply Application Guide provide details on these application types. Only those application types listed here are allowed for this NOFO.
Award budget
Application budgets are limited to 250,000 direct costs per year excluding consortium F&A costs) and need to reflect the actual needs of the proposed project.
Project period
The scope of the proposed project should determine the project period. The maximum project period is 4 years. NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO.
Funds available and number of awards
The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications.

Summarized from the NOFO text; the full NOFO governs eligibility, budget, and review.

Related NOFOs

  • Reissue of PAR-20-304.

Other open NOFOs for R01

Browse all open NIH NOFOs

About this page

GotGrant gathers the NOFO, its participation and change notices, and its NOSIs from the NIH Guide for Grants and Contracts, and counts funded projects from NIH RePORTER by the opportunity number each award was made under. Data refreshed October 16, 2026; the NIH Guide is the authoritative source. See our data methodology.

Find who wins under this NOFO