NIH PAR · NLM · R01
PAR-26-040: Advancing Bioinformatics, Translational Bioinformatics and Computational Biology Research (R01 Clinical Trial Optional)
Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards
The National Library of Medicine (NLM) seeks applications for research projects that drive groundbreaking innovation and advanced development in the fields of bioinformatics, translational bioinformatics, and computational biology. The primary goal of this initiative is to support the creation and implementation of cutting-edge methods, tools, and approaches that can transform the landscape of biomedical data science. This NOFO aims to address the growing need to leverage transformative technologies — such as artificial intelligence (AI), machine learning, and large-scale computational platforms — to extract actionable knowledge from vast, diverse, and complex biological datasets. By…
- NOFO number
- PAR-26-040
- Type
- PAR
- Activity code
- R01
- Primary institute
- NLM · National Library of Medicine
- Clinical trials
- Optional
- Posted
- Feb 11, 2026
- Opens
- Apr 6, 2026
- Expires
- Mar 6, 2029
PAR-26-040 due dates
7 application due dates remain before the NOFO expires. Dates marked * are NIH standard due dates. Check the related notices below for changes NIH made after posting.
| New | Renewal / Resubmission / Revision (as allowed) | AIDS - New/Renewal/Resubmission/Revision, as allowed | Scientific Merit Review | Advisory Council Review | Earliest Start Date |
|---|---|---|---|---|---|
| June 05, 2026 * | July 05, 2026 * | Not Applicable | November 2026 | January 2027 | April 2027 |
| October 05, 2026 * | November 05, 2026 * | Not Applicable | March 2027 | May 2027 | July 2027 |
| February 05, 2027 * | March 05, 2027 * | Not Applicable | July 2027 | October 2027 | December 2027 |
| June 05, 2027 * | July 05, 2027 * | Not Applicable | November 2027 | January 2028 | April 2028 |
| October 05, 2027 * | November 05, 2027 * | Not Applicable | March 2028 | May 2028 | July 2028 |
| February 05, 2028 * | March 05, 2028 * | Not Applicable | July 2028 | October 2028 | December 2028 |
| June 05, 2028 * | July 05, 2028 * | Not Applicable | November 2028 | January 2029 | April 2029 |
| October 05, 2028 * | November 05, 2028 * | Not Applicable | March 2029 | May 2029 | July 2029 |
| February 05, 2029 * | March 05, 2029 * | Not Applicable | July 2029 | October 2029 | December 2029 |
Funded projects
NIH RePORTER lists no awards under PAR-26-040 in FY2022–FY2026, and it is a new NOFO rather than a reissue. Awards usually appear a few months after the first review cycle.
Participating institutes
2 NIH institutes and offices take applications under PAR-26-040. Contact the program officer at the institute that fits your research before applying.
- NLM · National Library of Medicine
- none
Related notices
NIH lists no related notices for PAR-26-040 yet.
Award terms
- Application types allowed
- New Renewal Resubmission Revision The OER Glossary and the How to Apply Application Guide provide details on these application types. Only those application types listed here are allowed for this NOFO.
- Award budget
- Application budgets are limited to 250,000 per year in direct costs and need to reflect the actual needs of the proposed project.
- Project period
- The scope of the proposed project should determine the project period. The maximum project period is 4 years. NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO.
- Funds available and number of awards
- The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications.
Summarized from the NOFO text; the full NOFO governs eligibility, budget, and review.
Other open NOFOs for R01
- PAR-25-131Computational Approaches to Curation at Scale for Biomedical Research Assets (R01 Clinical Trial Not Allowed)NLM · next due Jan 15, 2027
- PAR-26-042Research Grants in Clinical Informatics (R01 Clinical Trial Optional)NLM · next due Feb 5, 2027
- PAR-25-235Personal Health Informatics for Delivering Actionable Insights to Individuals (R01 Clinical Trial Optional)NLM
- PAR-25-379Intervention Research to Improve Native American Health (R01 Clinical Trial Optional)NIDA · next due Oct 21, 2026
- PAR-25-322Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Clinical Trial Not Allowed)OD · next due Jan 26, 2027
- PA-25-301NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed)NIH · next due Feb 5, 2027
About this page
GotGrant gathers the NOFO, its participation and change notices, and its NOSIs from the NIH Guide for Grants and Contracts, and counts funded projects from NIH RePORTER by the opportunity number each award was made under. Data refreshed October 16, 2026; the NIH Guide is the authoritative source. See our data methodology.