UU Series — Cooperative Agreements

NIH UM1 Grants — Multi-Component Cooperative Agreement

Large multi-component research with NIH involvement

Funding

Multi-million per year

Duration

5 years

Eligibility

Multi-component team programs

Activity code

UM1

What is the NIH UM1 grant?

UM1 awards fund large multi-component research programs that combine multiple research projects and cores under a single cooperative agreement umbrella.

Recent UM1 awards (last 24 months)

Live data from NIH RePORTER

428

Awards

$1,495,709,166

Total funding (sample)

$3,494,648

Average award

Sample reflects up to the most recent 500 NIH RePORTER awards with this activity code in the past 24 months. Total project count is the full RePORTER count.

Most recently awarded UM1 grants

ATOPIC DERMATITIS RESEARCH NETWORK LEADERSHIP CENTER

Donald Leung · NATIONAL JEWISH HEALTH, CO · NIH

$4,361,109

FY 2026

Project: 5UM1AI151958-07

Development of a Longitudinal Observational Research Registry for the Study of Medicinal Cannabis Use and Health

RYAN VANDREY · JOHNS HOPKINS UNIVERSITY, MD · NIH

$2,001,470

FY 2026

Project: 5UM1DA059000-04

CTSA UM1 Program at University of California San Diego Altman Clinical and Translational Research Institute

David Smith · UNIVERSITY OF CALIFORNIA, SAN DIEGO, CA · NIH

$10,295,345

FY 2026

Project: 5UM1TR005449-02

Pediatric Brain Tumor Consortium A multi-institutional consortium devoted to novel phase I and II clinical evaluations of experimental treatment approaches for pediatric CNS tumors

Arzu Onar-Thomas · ST. JUDE CHILDREN'S RESEARCH HOSPITAL, TN · NIH

$1,423,203

FY 2026

Project: 3UM1CA081457-25S2

Targeting T cell Subsets in Autoimmune Disease

John Stone · MASSACHUSETTS GENERAL HOSPITAL, MA · NIH

$333,918

FY 2026

Project: 5UM1AI144295-08

AIDS Clinical Trial Group Laboratory Center

Grace Aldrovandi · UNIVERSITY OF CALIFORNIA LOS ANGELES, CA · NIH

$799,305

FY 2026

Project: 3UM1AI106701-13S1

CTSA UM1 Program at University of Utah

RACHEL HESS · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH, UT · NIH

$5,598,722

FY 2026

Project: 5UM1TR004409-04

Scripps Clinical and Translational Science Hub

Eric Topol · SCRIPPS RESEARCH INSTITUTE, THE, CA · NIH

$6,074,495

FY 2026

Project: 5UM1TR004407-04

Top NIH institutes funding UM1

By total funding in the last 24 months

  1. 1.NIH428 · $1,495,709,166

Top funded institutions

Most UM1 awards in the last 24 months

  1. 1.JOHNS HOPKINS UNIVERSITY43 awards
  2. 2.UNIVERSITY OF CALIFORNIA LOS ANGELES26 awards
  3. 3.FRED HUTCHINSON CANCER CENTER22 awards
  4. 4.UNIV OF NORTH CAROLINA CHAPEL HILL18 awards
  5. 5.ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI13 awards
  6. 6.EMORY UNIVERSITY13 awards

Who applies for UM1

Established multi-institution teams responding to specific UM1 FOAs.

When to choose UM1

When the FOA specifies UM1 — common for clinical trials networks and large consortia.

When NOT to choose UM1

When P01/P50 structure suits your program better.

Search tips for UM1

  • UM1 awards identify NIH consortia and clinical trial networks.

Search NIH grants by activity code

Open NIH grant search

Find UM1-funded PIs

Open PI Finder

UM1 funding trends

Open trend search

Related NIH grant types

UU01

Research Project — Cooperative Agreement

Investigator-led research with NIH staff substantial involvement

UU54

Specialized Center — Cooperative Agreement

Multi-component centers with NIH program involvement