NIH U54 Grants — Specialized Center — Cooperative Agreement

Recent U54 awards from NIH RePORTER

Examples of funded U54 projects across the last two fiscal years. The matching-award count comes from the full result set; funding totals, averages, rankings, and examples use the first 500 records returned by NIH RePORTER. Figures reflect a snapshot last refreshed on September 5, 2026.

Example U54 projects from the sample

• The Center for Innovation in Point-of-Care Technologies for HIV/AIDS and Emerging Infectious Diseases at Northwestern University (C-THAN)

  7U54EB027049-09
  Chad Achenbach · NORTHWESTERN UNIVERSITY, IL · $1,638,656 · awarded Aug 28, 2026 · NIH

  SUMMARY - OVERALL The Center for Innovation in Point-of-Care Technologies for HIV/AIDS and Emerging Infectious Diseases at Northwestern (C-THAN) proposes to remain a member in the Point-of-Care Technologies Research Network (POCTRN) as a Technology Research and Development Center (TRDC). C-THAN will catalyze innovation in diagnostic technologies through a…

• Center for Innovative NeuroTech Advancement - CINTA (19819 Neurologic Solutions, Inc. Yr2)

  3U54EB033650-05SD
  STEVEN SCHACHTER · MASSACHUSETTS GENERAL HOSPITAL, MA · $716,090 · awarded Aug 27, 2026 · NIH

  Project Abstract EpiScalp is a software application that is designed to apply advanced analytics to EEG data in order to assist neurologists in diagnosing epilepsy. EpiScalp is a novel EEG algorithm that uses 10-30 minutes of scalp EEG to provide an epilepsy risk score ranging from 0-100 in just seconds. Importantly, EpiScalp does not rely on IEDs or other…

• Stem Cell and Transplantation Biology

  5U54DK106829-12
  DEREK STIREWALT · FRED HUTCHINSON CANCER CENTER, WA · $877,378 · awarded Aug 27, 2026 · NIH

  The theme of this CCEH is focused on stem cell and transplantation biology. The aims are designed to overcome obstacles that prevent new investigators from joining this field. Specifically, the cores will provide investigators access to: Large numbers of human stem/progenitor cells; Scalable viral production services for AAV, gamma-, lenti- and foamy…

• Center for Iron & Heme Disorders at the University of Utah

  5U54DK110858-11
  Anna E Beaudin · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH, UT · $696,973 · awarded Aug 26, 2026 · NIH

  Project Summary: The proposed University of Utah Cooperative Centers of Excellence in Hematology (CCEH) brings together 38 investigators whose research activities are focused on various aspects of iron and heme metabolism and non- malignant hematology. Iron plays an essential role in many biological processes including heme synthesis, oxygen transport,…

• Hematopoietic stem and progenitor cell regulation for enhanced clinical efficacy

  5U54DK106846-11
  Reuben Kapur · INDIANA UNIVERSITY INDIANAPOLIS, IN · $700,000 · awarded Aug 26, 2026 · NIH

  OVERALL CENTER PROJECT SUMMARY The proposed Indiana University School of Medicine (IUSM) Cooperative Center of Excellence in Hematology (CCEH) brings together 25 investigators whose research activities are focused on various aspects of nonmalignant hematology and whose work is highly dependent on one or more of the three biomedical research cores proposed…

• Yale Cooperative Center of Excellence in Hematology

  5U54DK106857-11
  Diane Krause · YALE UNIVERSITY, CT · $699,999 · awarded Aug 26, 2026 · NIH

  Abstract The purpose of the Yale Cooperative Center of Excellence in Hematology (YCCEH) is to facilitate and enhance research by investigators engaged in nonmalignant hematology-related research. Our unique focus is the application of emerging technologies to the study of normal and perturbed hematopoiesis. This includes understanding stem cell biology,…

• Artificial Intelligence, Modeling, and Informatics for Nutrition Guidance and Systems (AIMINGS) Center

  5U54TR004279-05
  Bruce Lee · GRADUATE SCHOOL OF PUBLIC HEALTH AND HEALTH POLICY, NY · $1,126,235 · awarded Aug 26, 2026 · NIH

  Abstract – Overall AIMINGS Center The vision of this proposed Artificial Intelligence, Modeling, and Informatics, for Nutrition Guidance and Systems (AIMINGS) Center is to implement computational and data science approaches and tools to advance nutrition for precision health in a way that accounts for the complex systems involved. Many existing data sets…

• Center for Innovative NeuroTech Advancement - CINTA

  3U54EB033650-05SC
  STEVEN SCHACHTER · MASSACHUSETTS GENERAL HOSPITAL, MA · $183,673 · awarded Aug 26, 2026 · NIH

  Project Summary / Abstract Early-stage projects often lack access to structured mentorship, administrative infrastructure, and milestone-driven oversight necessary to efficiently translate promising innovations toward clinical and commercial impact. The Sprinter Program aims to address these gaps by providing expert mentorship, centralized administrative…

• Atlanta Center for Microsystems Engineered Point-of-Care Technologies (ACME POCT)

  5U54EB027690-09
  Wilbur Lam · EMORY UNIVERSITY, GA · $1,561,849 · awarded Aug 25, 2026 · NIH

  Since the advent of point-of-care diagnostics (POCD) several decades ago, one class of novel medical technologies that has shown promise for POCD applications is microsystems diagnostics--microchip-enabled tests ranging from microelectromechanical systems (MEMs)-based sensors, microfluidics, to smartphone-based systems. Notable for their small size, low…

• Center for Innovative NeuroTech Advancement - CINTA (20409 CoolSpine, LLC. Yr2)

  3U54EB033650-05SB
  STEVEN SCHACHTER · MASSACHUSETTS GENERAL HOSPITAL, MA · $1,481,027 · awarded Aug 25, 2026 · NIH

  BPMT 20409 Intrathecal Cooling Catheter to Provide Neuroprotection to Avoid Paraplegia Resulting from Open and Endovascular Thoracic Aneurysm Repair Project Abstract Abstract: This proposal is responsive to NIH’s sponsorship of the 2023 International Symposium Eliminating Paralysis after Aortic Surgery and seeks to translate CoolSpine’s novel Intrathecal…

• The RCMI Program in Health Disparities Research at Meharry Medical College

  5U54MD007586-40
  Samuel Adunyah · MEHARRY MEDICAL COLLEGE, TN · $2,488,885 · awarded Aug 24, 2026 · NIH

  ABSTRACT The RCMI Program in Health Disparities Research at Meharry Medical College (RHDR@MMC) proposes to address health disparities at multiples scales of research: from micro to macro environments. With strengthened institutional collaboration and support, this renewal application seeks to expand the long-term RCMI support of enabling high quality basic,…

• The Center for Innovation and Translation of Point of Care Technologies for Expanded Cancer Care Access (CITEC)

  3U54EB034652-04S2
  Rebecca Richards-Kortum · RICE UNIVERSITY, TX · $13,791 · awarded Aug 24, 2026 · NIH

  Cancer is the first or second leading cause of premature death in 134 of 183 countries, and it is estimated that global incidence of cancer will increase by 50% from 2018 to 2040. The number of cases is projected to double in countries with low Human Development Index; these countries have the least resources and infrastructure to adequately care for cancer…

Compare nearby NIH grant mechanisms

Searchers often land on U54 while deciding between adjacent NIH activity codes. Compare scope, NIH staff involvement, budget scale, and applicant stage before choosing a funding opportunity.

Open NIH NOFOs for U54

NIH accepts U54 applications only through a notice of funding opportunity (NOFO). These 3 are open or opening soon; each page lists due dates, participating institutes, related notices, and the projects NIH funded under it.