NIH P50 Grants — Specialized Center Grant

Recent P50 awards from NIH RePORTER

Examples of funded P50 projects across the last two fiscal years. The matching-award count comes from the full result set; funding totals, averages, rankings, and examples use the first 500 records returned by NIH RePORTER. Figures reflect a snapshot last refreshed on September 5, 2026.

Example P50 projects from the sample

• Vanderbilt-Ingram Cancer Center SPORE in Gastrointestinal Cancer

  5P50CA236733-07
  Robert Coffey · VANDERBILT UNIVERSITY MEDICAL CENTER, TN · $2,317,951 · awarded Aug 28, 2026 · NIH

  PROJECT SUMMARY/ABSTRACT: Overall This application is an A1 submission of the Vanderbilt-Ingram Cancer Center Gastrointestinal SPORE, which will focus on colorectal cancer, the second leading cause of cancer-related deaths in the United States. Our potential for success is high based on 1) productivity during the previous cycle of the GI SPORE, 2)…

• Molecularly Targeted Radiosensitization of Locally Advanced Cancers

  5P50CA269022-04
  THEODORE LAWRENCE · UNIVERSITY OF MICHIGAN AT ANN ARBOR, MI · $1,985,638 · awarded Aug 26, 2026 · NIH

  PROJECT SUMMARY (OVERALL) Cancer cannot be cured unless the primary tumor is cured. For patients with locally advanced or unresectable disease for whom initial surgery is not an option, radiation therapy (RT) combined with a systemic agent has become the standard treatment. This is because systemic therapy alone can rarely cure gross disease, but can…

• Route 66 Endometrial Cancer SPORE

  5P50CA265793-04
  David Mutch · WASHINGTON UNIVERSITY, MO · $1,700,196 · awarded Aug 26, 2026 · NIH

  The Route 66 Endometrial Cancer SPORE brings together interactive research teams from three institutions to create a dynamic translational research program aimed at developing and testing new strategies to prevent and treat endometrial cancer. This SPORE includes three research projects; an administrative core; a biostatistics and bioinformatics core; a…

• Genetics of Male Infertility: Accelerating the pace of discovery

  6P50HD096723-08
  Kyle Orwig · UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA · $1,625,266 · awarded Aug 26, 2026 · NIH

  Abstract: Overall Azoospermia impacts 1% of men globally, which translates to 645,000 men between the ages of 20 and 50 in the United States. It is estimated that genetic causes explain 50% of infertility. Improved knowledge about the genetic basis of infertility and associated overall health comorbidities will aid in the counseling of infertile couples;…

• Neuroendocrine Tumor Specialized Programs of Research Excellence (SPORE) in Human Cancer

  5P50CA302572-02
  DAWN QUELLE · UNIVERSITY OF IOWA, IA · $2,146,411 · awarded Aug 25, 2026 · NIH

  Overall – Summary Neuroendocrine tumors (NETs) and neuroendocrine carcinomas (NECs) are orphan cancers whose incidence and prevalence are increasing in the US. NETs are slow-growing, yet relentlessly progressive and are notoriously resistant to chemotherapy. The University of Iowa is one of only a handful of institutions where patients with NETs and NECs…

• University of Texas Southwestern Medical Center SPORE in Kidney Cancer

  5P50CA196516-10
  James Brugarolas · UT SOUTHWESTERN MEDICAL CENTER, TX · $2,337,000 · awarded Aug 24, 2026 · NIH

  Overall Summary Particularly prevalent in Texas, renal cell carcinoma (RCC) is lethal when metastatic. To address this unmet medical need, the UTSW Kidney Cancer SPORE has developed a comprehensive therapeutic program in proven (targeted therapies and immunotherapy) and innovative (metabolism-directed) areas. Arguably, the most important driver of RCC is…

• UCLA IDDRC

  3P50HD103557-05S2
  HARLEY KORNBLUM · UNIVERSITY OF CALIFORNIA LOS ANGELES, CA · $1,093,170 · awarded Aug 24, 2026 · NIH

  Abstract from the original application: For over 55 years, our mission has been to provide an optimal environment for conducting multidisciplinary research into the mechanisms underlying intellectual and developmental disabilities (IDDs), to translate these findings into effective treatments for IDDs, and disseminate these findings to the scientific…

• Optimization of Antibiotics in Mothers and their Breastfed Infants Using Pharmacomicrobiomic and Metabolomic Analyses

  3P50HD106463-05S1
  ADRIANA TREMOULET · UNIVERSITY OF CALIFORNIA, SAN DIEGO, CA · $1,190,453 · awarded Aug 24, 2026 · NIH

  PROJECT SUMMARY Our UC San Diego MPRINT CET, “Optimization of Antibiotics in Mothers and Their Breastfed Infants Using Pharmacomicrobiomic and Metabolomic Analyses”, has brought together a team of highly experienced and proven collaborative investigators with leadership roles in maternal and pediatric clinical pharmacology and associated fundamental…

• SPORE for Translational Approaches to Brain Cancer

  5P50CA221747-09
  MACIEJ LESNIAK · NORTHWESTERN UNIVERSITY, IL · $2,114,370 · awarded Aug 21, 2026 · NIH

  OVERALL: SUMMARY The overall objective of the Northwestern Brain Tumor SPORE is to improve outcomes for brain tumor patients. Of the various primary intracerebral neoplasms, glioblastoma (GBM) is the most common. GBM patients that receive standard-of-care treatment have a median survival of 20 months, and 5-year survival is extremely rare. Progress in…

• Neural-immune Mechanisms and Synaptic Connectivity in Psychiatric Illness

  5P50MH112491-10
  Beth Stevens · BOSTON CHILDREN'S HOSPITAL, MA · $3,152,705 · awarded Aug 20, 2026 · NIH

  The pathophysiology of schizophrenia has been unknown, resulting in a lack of innovative therapeutics with novel mechanisms of action. The Conte Center for Neuroimmune Studies was created to build on our discovery that the biology underlying the most significant schizophrenia common genetic risk variants involves neuroimmune mechanisms of synaptic pruning.…

• Mental Health in Autistic Adults: An RDoC Approach

  5P50MH130957-05
  Carla Mazefsky · UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA · $2,256,422 · awarded Aug 19, 2026 · NIH

  The University of Pittsburgh Autism Center of Excellence (ACE) directly addresses the Interagency Autism Coordinating Committee’s call for research on adult mental health to improve safety and quality of life, and to reduce premature mortality. We do so by generating the measures and mechanistic targets needed to improve mental health and reduce suicide…

• Emory University Lung Cancer SPORE

  1P50CA302567-01A1
  Suresh Ramalingam · EMORY UNIVERSITY, GA · $2,194,434 · awarded Aug 18, 2026 · NIH

  OVERALL SUMMARY/ABSTRACT Lung cancer is the leading cause of cancer-related deaths, with more than 1.8 million deaths/year globally. It is often diagnosed at an advanced stage and is associated with poor outcomes for most patients. This revised application for the Emory Lung Cancer SPORE award includes an outstanding multi-disciplinary team of clinical…

Compare nearby NIH grant mechanisms

Searchers often land on P50 while deciding between adjacent NIH activity codes. Compare scope, NIH staff involvement, budget scale, and applicant stage before choosing a funding opportunity.

Open NIH NOFOs for P50

NIH accepts P50 applications only through a notice of funding opportunity (NOFO). These 3 are open or opening soon; each page lists due dates, participating institutes, related notices, and the projects NIH funded under it.