NIH P01 Grants — Program Project Grant

Recent P01 awards from NIH RePORTER

Examples of funded P01 projects across the last two fiscal years. The matching-award count comes from the full result set; funding totals, averages, rankings, and examples use the first 500 records returned by NIH RePORTER. Figures reflect a snapshot last refreshed on June 9, 2026.

Example P01 projects from the sample

• Pathways Regulating Lung Transplant Tolerance

  5P01AI116501-12
  Daniel Kreisel · WASHINGTON UNIVERSITY, MO · $1,474,042 · awarded Jun 3, 2026 · NIH

  PROJECT SUMMARY / ABSTRACT Lung transplantation, the only available therapy for many patients who suffer from end-stage pulmonary failure, continues to be plagued by disappointing long-term survival rates. Our research suggests that the premature demise of many transplanted lungs is in large part due to the use of immunosuppression that is not tailored…

• Neutrophil heterogeneity in immune regulation

  1P01AI194958-01
  Hongbo Luo · BRIGHAM AND WOMEN'S HOSPITAL, MA · $2,472,443 · awarded Jun 3, 2026 · NIH

  Project Summary Neutrophils play a critical role in innate immunity and host defense against invading microorganisms, but also contribute pathogenically to a number of non-infectious conditions including asthma, multiple sclerosis, rheumatoid arthritis, gastritis, inflammatory bowel disease, cancer, and ischemia-induced tissue damage. Disentangling the…

• SORL1 and its involvement in Alzheimer's disease pathogenesis and pathophysiology

  5P01AG090268-02
  SCOTT SMALL · COLUMBIA UNIVERSITY HEALTH SCIENCES, NY · $3,187,703 · awarded Jun 3, 2026 · NIH

  OVERALL PROJECT SUMMARY/ABSTRACT SORL1 is emerging as only the 4th gene that is considered causal in Alzheimer’s disease. New insight shows how SORL1 functions by interacting with the retromer trafficking complex, how disrupting this interaction can mediate the disease’s cardinal pathologies, and how SORL1-retromer disruptions have been commonly linked to…

• Frontotemporal Dementia: Genes, Images, and Emotions

  3P01AG019724-24S2
  MARIA LUISA GORNO TEMPINI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA · $27,000 · awarded Jun 2, 2026 · NIH

  PROJECT SUMMARY—Frontotemporal Dementia (FTD): Genes, Images, and Emotions Frontotemporal dementia (FTD) research is entering a new era of therapeutic discovery, spurred in part by contributions from this program project grant (PPG), entitled “Frontotemporal Dementia: Genes, Images, and Emotions,” which has a 20-year history of productivity and…

• Cellular cross-talk in autoimmune disease

  2P01AI148102-06
  Michael Brenner · BRIGHAM AND WOMEN'S HOSPITAL, MA · $2,412,120 · awarded Jun 1, 2026 · NIH

  The overall goal of this P01 is to determine how cells differentiate into states unique to human patients and animal models with autoimmune diseases, how these cells interact with other cells in their environment and how they contribute to disease pathogenesis. Project 1 will focus on the regulation and function of regulatory T cells (Tregs) through the…

• Tissue Regulation of T Cell Function

  2P01AI102851-11A1
  Deborah Fowell · CORNELL UNIVERSITY, NY · $2,676,294 · awarded Jun 1, 2026 · NIH

  PROJECT SUMMARY / ABSTRACT Successful immunity relies on the rapid orchestration of diverse immune cell types that work in a dynamic and cooperative manner to drive location-dependent effector function. Immune cells do not work in isolation, and cooperation between immune cell types requires the sensing of local position-dependent cues that enable immune…

• Frontotemporal Dementia: Genes, Images, and Emotions

  3P01AG019724-24S1
  MARIA LUISA GORNO TEMPINI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA · $13,716 · awarded Jun 1, 2026 · NIH

  PROJECT SUMMARY—Frontotemporal Dementia (FTD): Genes, Images, and Emotions Frontotemporal dementia (FTD) research is entering a new era of therapeutic discovery, spurred in part by contributions from this program project grant (PPG), entitled “Frontotemporal Dementia: Genes, Images, and Emotions,” which has a 20-year history of productivity and…

• Immune Function and the Progression to Type 1 Diabetes

  5P01AI042288-28
  Todd Brusko · UNIVERSITY OF FLORIDA, FL · $1,622,982 · awarded May 28, 2026 · NIH

  Type 1 diabetes (T1D) is a disorder that arises following the autoimmune destruction of insulin producing pancreatic β-cells. Previous studies, including nearly 120 peer reviewed-articles supported by this P01 over the current grant cycle, have demonstrated that individuals with or at increased-risk for T1D display a series of innate and adaptive…

• Immunoengineering Durable Control of HIV Replication

  5P01AI191610-02
  James Riley · UNIVERSITY OF PENNSYLVANIA, PA · $3,729,469 · awarded May 28, 2026 · NIH

  Despite anti-retroviral therapies (ART), HIV-1 continues to cause a considerable medical and economic burden, and there continues to be a pressing need for an HIV-1 cure. The goal of this Program is to generate a chimeric antigen receptor (CAR) approach that can control viral replication below the limit of detection and eliminate the viral reservoir. We…

• Microbiology of Treatment Shortening in Tuberculosis"

  1P01AI181935-01A1
  Dirk Schnappinger · WEILL MEDICAL COLL OF CORNELL UNIV, NY · $3,589,323 · awarded May 27, 2026 · NIH

  PROJECT SUMMARY/ABSTRACT - OVERALL Efforts to establish control of the tuberculosis (TB) pandemic face historically unprecedented challenges. In the wake of COVID-19-induced disruptions in TB healthcare-related services, TB has re-emerged as the leading cause of deaths due to an infectious disease with 2 consecutive years of the first increases in TB…

• Investigating cell-intrinsic and extrinsic interactions in prostate cancer at the single cell level

  5P01CA265768-05
  MICHAEL SHEN · COLUMBIA UNIVERSITY HEALTH SCIENCES, NY · $2,097,704 · awarded May 27, 2026 · NIH

  Project Summary/Abstract Prostate cancer progression to metastatic castration-resistant disease continues to represent a major health issue. Recent advances in single-cell approaches have revealed extensive heterogeneity and complexity of cell states and cell types that drive tumor progression, and additional studies have demonstrated the central role of…

• MARVEL: A Multidisciplinary Assessment of Risks from Vaping during Early Life

  5P01CA269048-04
  Erin Sutfin · WAKE FOREST UNIVERSITY HEALTH SCIENCES, NC · $1,893,034 · awarded May 27, 2026 · NIH

  ABSTRACT – OVERALL The proposed program project, A Multidisciplinary Assessment of Risks of Vaping in Early Life (Project MARVEL), takes an integrated approach to assessing vaping behavior and the emergence of dependence; elucidating the impact of vaping on adolescent health; and generating empirically-tested messages to reduce adolescent vaping. In 2020,…

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Searchers often land on P01 while deciding between adjacent NIH activity codes. Compare scope, NIH staff involvement, budget scale, and applicant stage before choosing a funding opportunity.