NIH Grant Search by PI — Funded Principal Investigator Finder

Search NIH grants by PI name or research area. Look up funded principal investigators, see their NIH RePORTER awards, institutions, and project details.

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Enter a research topic, disease, or technology to find principal investigators with NIH funding in that area. To look up a specific PI by name, use the PI Funding Status check.

Search Results

Found 266 principal investigators from 200 displayed projects for "P50" (2021–2026)

Note: 1,308 projects matched but only the first 200 were analyzed. Try narrowing your search with a more specific term or selecting "Project title only".

Opportunity Digest

Heuristic scoring to help trainees and job seekers prioritize which labs to inspect first.

17

High-opportunity leads

151

Likely hiring signals

29

Training-friendly awards

48

Average opportunity score

Prioritize records with strong opportunity signals, then validate fit using abstracts, institution pages, and lab websites.

Filter for opportunity type

Jeffrey L. Weiner

WAKE FOREST UNIVERSITY HEALTH SCIENCES, WINSTON-SALEM, NC

High-opportunity lead · 88/100
Likely hiring
Large award
Very recent
Active award
$1,526,194
FY 2026

Project Title

Wake Forest Translational Alcohol Research Center (WF-TARC)

Grant Number:

5P50AA026117-09

Activity Code:

P50

Mechanism:

Research Centers

Agency:

NIH

Start Date:

12/10/2017

End Date:

11/30/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

WAKE FOREST TRANSLATIONAL ALCOHOL RESEARCH CENTER (WF-TARC) OVERALL SUMMARY The central goal of the Wake Forest Translational Alcohol Research Center (WF-TARC) is to employ integrated, translational animal and human subjects research to study behavioral correlates and neurobiological substrates ass...

Research Terms

<Acceleration><Adolescent><Adolescent Youth><Alcohol Chemical Class><Alcohol Drinking><Alcohol consumption><Alcohols><Animal Model><Animal Models and Related Studies><Animals><Award><Behavior><Behavioral><Biometrics><Biometry><Biostatistics><Brain><Brain Nervous System><Collaborations><Communication><Community Education><Community Health Education><Development><Diagnosis><Disease><Disorder><Education><Education and Outreach><Educational aspects><Encephalon><Ensure><EtOH drinking><EtOH use><Experimental Designs><Faculty><Funding><Generalized Growth><Goals><Grant><Groups at risk><Growth><Health Care Systems><Human><Human Subject Research><Individual><Infrastructure><Institution><Instruction and Outreach><Investigators><Knowledge><Leadership><Learning><Measures><Methods><Modern Man><Molecular><Neural Development><Neurobiology><People at risk><Persons at risk><Pilot Projects><Play><Population><Populations at Risk><Postdoc><Postdoctoral Fellow><Pre-Clinical Model><Preclinical Models><Productivity><R-Series Research Projects><R01 Mechanism><R01 Program><Research><Research Associate><Research Design><Research Grants><Research Methodology><Research Methods><Research Personnel><Research Project Grants><Research Projects><Research Resources><Research Support><Researchers><Resources><Risk><Rodent><Rodentia><Rodents Mammals><Role><Science><Sleep disturbances><Students><Study Type><Substance Use Disorder><System><Talents><Tissue Growth><Training and Outreach><Translational Research><Translational Science><Translations><Treatment outcome><Tutoring and Outreach><Work><aberrant sleep><addiction><addictive disorder><alcohol abuse therapy><alcohol abuse treatment><alcohol ingestion><alcohol intake><alcohol product use><alcohol related research><alcohol research><alcohol treatment><alcohol use><alcohol use disorder><alcoholic beverage consumption><alcoholic drink intake><behavior study><behavioral study><classroom environment><college atmosphere><collegial atmosphere><collegiate atmosphere><computer based prediction><developmental><differentiation factors><disrupted sleep><disturbed sleep><drinking behavior><education atmosphere><educational atmosphere><educational environment><effective therapy><effective treatment><ethanol consumption><ethanol drinking><ethanol ingestion><ethanol intake><ethanol product use><ethanol research><ethanol use><ethanol use disorder><evidence base><human model><impaired sleep><improved><innovate><innovation><innovative><intellectual atmosphere><irregular sleep><juvenile><juvenile human><learning atmosphere><learning environment><medical college><medical schools><model of animal><model of human><morphogenic factors><morphogens><multidisciplinary><neural><neural correlate><neurobiological><neurodevelopment><new approaches><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><next generation><non-human primate><nonhuman primate><novel><novel approaches><novel strategies><novel strategy><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><ontogeny><pilot study><post-doc><post-doctoral><post-doctoral trainee><predictive modeling><programs><recruit><research and methods><research associates><resilience><resilient><school atmosphere><school climate><school of medicine><sleep disruption><sleep dysregulation><sleep/wake disruption><sleep/wake disturbance><social role><study design><substance use and disorder><success><training atmosphere><training opportunity><translation><translation research><translational investigation><translational therapeutics><translational therapy><university atmosphere>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Carol A. Casey

UNIVERSITY OF NEBRASKA MEDICAL CENTER, OMAHA, NE

High-opportunity lead · 74/100
Likely hiring
Large award
Active award
Team-scale grant
$1,588,725
FY 2026

Project Title

Alcohol Center Of Research -- Nebraska (ACORN)

Grant Number:

5P50AA030407-04

Activity Code:

P50

Mechanism:

Research Centers

Agency:

NIH

Start Date:

2/28/2023

End Date:

1/31/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

The goal of the Alcohol Center of Research-Nebraska (ACORN) is to expand existing strengths and expertise in Nebraska to develop a novel niche in alcohol research, by creating a Center focused on the Alcohol Exposome. Alcohol research has been a major area of emphasis in Nebraska (at the Omaha VA Me...

Research Terms

<Address><Age><Aging><Alcohol Chemical Class><Alcohol Drinking><Alcohol consumption><Alcoholic><Alcoholic Fatty Liver><Alcoholic Liver Diseases><Alcohols><Aldehydes><Animals><Area><Bacterial Pneumonia><Basic Research><Basic Science><Biology><Boozer><Brain><Brain Nervous System><Cannabis Smoking><Categories><Causality><Cell Communication and Signaling><Cell Signaling><Cell model><Cellular injury><Cellular model><Cigarette><Collaborations><Dedications><Dependent drinker><Development><Disease><Disease Progression><Disorder><Dysfunction><Encephalon><Environment><Environmental Exposure><Environmental Factor><Environmental Risk Factor><EtOH drinking><EtOH use><Etiology><Event><Exposure to><Faculty><Foundations><Functional disorder><Funding><Funding Opportunities><Future><Goals><Grant><HBV infection><Health><Heart Injuries><Hepatic><Hepatitis B Infection><Human><Immune><Immunes><Immunity><Incidence><Individual><Infection><Injury to Liver><Innate Immunity><Institution><Interdisciplinary Research><Interdisciplinary Study><Intracellular Communication and Signaling><Investigation><Investigators><Knowledge><Liver><Lung><Lung Respiratory System><Marijuana Smoking><Medical center><Modern Man><Molecular><Multidisciplinary Collaboration><Multidisciplinary Research><NIAAA><National Institute on Alcohol Abuse and Alcoholism><Native Immunity><Natural Immunity><Nature><Nebraska><Non-Specific Immunity><Nonspecific Immunity><Nutritional><Nutritional status><Obesity><Occupational><Organ><Physiology><Physiopathology><Pilot Projects><Predisposition><Protein Trafficking><R-Series Research Projects><R01 Mechanism><R01 Program><Research><Research Grants><Research Personnel><Research Project Grants><Research Projects><Research Resources><Researchers><Resources><Role><Scientist><Services><Shapes><Signal Transduction><Signal Transduction Systems><Signaling><Structure><Susceptibility><Talents><Tissue Model><Tobacco><Toxin><Trace metal><Training><Translating><Translational Research><Translational Science><United States><United States Department of Veterans Affairs><United States Veterans Administration><Universities><Veterans Administration><Veterans Affairs><Work><Zinc decreased><Zinc deficiency><Zinc low><Zn deficiency><Zn levels low><Zn++ low><adduct><adiposity><ages><alcohol effect><alcohol induced hepatic injury><alcohol induced liver disorder><alcohol induced liver injury><alcohol ingestion><alcohol intake><alcohol misuse><alcohol product use><alcohol related liver disease><alcohol related research><alcohol research><alcohol use><alcohol-associated liver disease><alcohol-induced hepatic dysfunction><alcohol-induced liver disease><alcohol-induced liver dysfunction><alcohol-mediated liver dysfunction><alcohol-mediated liver injury><alcohol-related liver disease><alcoholic beverage consumption><alcoholic drink intake><alcoholic liver injury><animal tissue><bacteria pneumonia><biological signal transduction><cardiac injury><causation><cell damage><cell injury><cellular damage><cigarette smoking><cigarette use><clinical translation><clinically translatable><co-morbid><co-morbidity><college><collegiate><comorbidity><conference><convention><corpulence><damage to cells><developmental><disease causation><environmental risk><ethanol consumption><ethanol drinking><ethanol effect><ethanol induced hepatic injury><ethanol induced liver disorder><ethanol induced liver injury><ethanol ingestion><ethanol intake><ethanol liver disease><ethanol misuse><ethanol product use><ethanol research><ethanol use><ethanol-induced hepatic dysfunction><ethanol-induced liver disease><ethanol-induced liver dysfunction><ethanol-mediated liver dysfunction><ethanol-mediated liver injury><exposome><exposure to environmental agents><exposure to environmental factors><exposure to environmental stimuli><exposure to environmental substances><hepatic body system><hepatic damage><hepatic injury><hepatic organ system><hepatitis B viral infection><hepatitis B virus infection><human tissue><infected with HBV><infected with hepatitis B><infected with hepatitis B virus><infection with HBV><infection with hepatitis B virus><injury to cells><injury to tissue><insight><life-style factor><lifestyle factors><liver damage><liver injury><low Zinc level><member><metal metabolism><multidisciplinary><multiorgan damage><novel><nutritious><pathogen><pathophysiology><pilot study><problem drinker><protein transport><recruit><social role><summit><symposia><symposium><tissue injury><training opportunity><translation research><translational investigation><unhealthy alcohol use>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jennifer L. Guerriero

BRIGHAM AND WOMEN'S HOSPITAL, BOSTON, MA

High-opportunity lead · 74/100
Likely hiring
Above-average budget
Very recent
Active award
$772,208
FY 2026

Project Title

Macrophage-directed strategies for BRCA-associated breast cancer

Grant Number:

1R01CA307291-01

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/10/2026

End Date:

3/31/2031

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY Poly (ADP-ribose) polymerase inhibitors (PARPi’s) are a promising treatment for BRCA-associated breast cancer, exerting synthetic lethal effects in homologous recombination (HR) repair-deficient tumor cells, yet clinical results are not durable. Our team has demonstrated that PARPi-m...

Research Terms

<Address><Agonist><Antibodies><Antitumor Response><B7-H1><BRCA 1/2><BRCA deficient><BRCA1/2><Biology><Biopsy><Biopsy Sample><Biopsy Specimen><Bp50><Breast Cancer><Breast Cancer Model><Breast Neoplasms><Breast Tumors><Breast tumor model><CD115><CD115 Gene><CD274><CD40><CD8 Cell><CD8 T cells><CD8 lymphocyte><CD8+ T cell><CD8+ T-Lymphocyte><CD8-Positive Lymphocytes><CD8-Positive T-Lymphocytes><CDW40><CSF1R><CSF1R gene><CSFMR><Cancers><Cell Communication and Signaling><Cell Function><Cell Physiology><Cell Process><Cell Signaling><Cell Survival><Cell Viability><Cell-Mediated Lympholytic Cells><Cellular Function><Cellular Physiology><Cellular Process><Clinical><Clinical Data><Clinical Trials><Colony Stimulating Factor 1 Receptor Gene><Complex><Cyclicity><Cytolytic T-Cell><Cytotoxic T Cell><Cytotoxic T-Lymphocytes><DNA Damage><DNA Damage Repair><DNA Injury><DNA Repair><DNA Repair Inhibition><Data><Dendritic Cells><Disease><Disorder><Early-Stage Clinical Trials><Enrollment><GEM model><GEMM model><Gene Transcription><Genetic Transcription><Genetically Engineered Mouse><Goals><Human><Immune infiltrates><Immune response><Immunochemical Immunologic><Immunocompetent><Immunofluorescence><Immunofluorescence Immunologic><Immunologic><Immunologic Subtyping><Immunological><Immunologically><Immunologics><Immunomodulation><Immunophenotyping><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><Infiltration><Intracellular Communication and Signaling><Lead><Lipids><MGC9013><Macrophage><Macrophage Activation><Malignant Breast Neoplasm><Malignant Neoplasms><Malignant Tumor><Mammary Cancer><Mammary Neoplasms><Mediating><Medical><Metabolic><Mice><Mice Mammals><Modeling><Modern Man><Murine><Mus><Myeloid Cells><Mφ><Nature><PALB2><PALB2 gene><PARP Inhibitor><PARP inhibition><PARP-1 inhibitor><PARPi><PD 1><PD-1><PD-1 antibody><PD-L1><PD1><PD1 antibody><PDL-1><Pathway interactions><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Pb element><Periodicity><Phase 1 Clinical Trials><Phase I Clinical Trials><Phenotype><Pilot Projects><Poly(ADP-ribose) Polymerase Inhibitor><Poly(ADP-ribose) polymerase 1 inhibitor><Polymerase><Population><Pre-Clinical Model><Preclinical Models><Preclinical data><Programmed Cell Death 1 Ligand 1><Programmed Death Ligand 1><RNA Expression><Resistance><Rhythmicity><Sampling><Signal Transduction><Signal Transduction Systems><Signaling><Stimulator of Interferon Genes><Subcellular Process><T cell response><T-Cell Activation><T-Cells><T-Lymphocyte><T8 Cells><T8 Lymphocytes><TNBC><TNFRSF5><TNFRSF5 gene><Testing><Therapeutic><Training><Transcription><Tumor Cell><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><Tumor-Derived><Tumor-associated macrophages><Unscheduled DNA Synthesis><Veiled Cells><Work><aPD-1><aPD1><activate T cells><advanced breast cancer><advanced stage breast cancer><anti programmed cell death 1><anti-PD-1><anti-PD-1 Ab><anti-PD-1 antibodies><anti-PD-1 monoclonal antibodies><anti-PD1><anti-PD1 Ab><anti-PD1 antibodies><anti-PD1 monoclonal antibodies><anti-programmed cell death protein 1><anti-programmed cell death protein 1 antibodies><anti-programmed death-1 antibody><anti-tumor response><antiPD-1><biological signal transduction><brca gene><c-FMS><c-fms Genes><c-fms Proto-Oncogenes><cGAMP STING><cGAMP-STING><cGAMP/STING><cGAS/STING><cancer microenvironment><clinical relevance><clinically relevant><cyclic GMP-AMP synthase/STING><determine efficacy><early clinical trial><early phase clinical trial><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><efficacy study><enroll><evaluate efficacy><examine efficacy><genetically engineered mouse model><genetically engineered murine model><heavy metal Pb><heavy metal lead><homologous recombination deficiency><homologous recombination repair deficiency><host response><immune cell infiltrate><immune competent><immune microenvironment><immune modulation><immune regulation><immune suppression><immune suppressive activity><immune suppressive function><immune suppressive macrophages><immune system response><immunologic reactivity control><immunomodulatory><immunoregulation><immunoregulatory><immunoresponse><immunosuppressive activity><immunosuppressive function><immunosuppressive macrophages><immunosuppressive microenvironment><immunosuppressive response><immunosuppressive tumor microenvironment><improved outcome><in vivo><inhibitor><inhibitor drug><inhibitor therapeutic><inhibitor therapy><killer T cell><malignancy><malignant breast tumor><mammary cancer model><mammary tumor><mammary tumor model><mouse model><murine model><neoplasm/cancer><neoplastic cell><p50><participant enrollment><partner and localizer of BRCA2><pathway><patient enrollment><patient oriented outcomes><phase I protocol><pilot study><pre-clinical><preclinical><preclinical findings><preclinical information><programmed cell death 1><programmed cell death ligand 1><programmed cell death protein 1><programmed cell death protein ligand 1><programmed death 1><protein death-ligand 1><recruit><resistance mechanism><resistant><resistant mechanism><response><scRNA sequencing><scRNA-seq><single cell RNA-seq><single cell RNAseq><single cell expression profiling><single cell transcriptomic profiling><single-cell RNA sequencing><sle2><spatial relationship><synergism><synthetic lethal interaction><synthetic lethality><systemic lupus erythematosus susceptibility 2><thymus derived lymphocyte><triple-negative breast cancer><triple-negative invasive breast carcinoma><tumor><tumor growth><tumor immune microenvironment><tumor microenvironment><tumor-immune system interactions><αPD-1><αPD1>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Filipa Lynce

BRIGHAM AND WOMEN'S HOSPITAL, BOSTON, MA

High-opportunity lead · 74/100
Likely hiring
Above-average budget
Very recent
Active award
$772,208
FY 2026

Project Title

Macrophage-directed strategies for BRCA-associated breast cancer

Grant Number:

1R01CA307291-01

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/10/2026

End Date:

3/31/2031

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY Poly (ADP-ribose) polymerase inhibitors (PARPi’s) are a promising treatment for BRCA-associated breast cancer, exerting synthetic lethal effects in homologous recombination (HR) repair-deficient tumor cells, yet clinical results are not durable. Our team has demonstrated that PARPi-m...

Research Terms

<Address><Agonist><Antibodies><Antitumor Response><B7-H1><BRCA 1/2><BRCA deficient><BRCA1/2><Biology><Biopsy><Biopsy Sample><Biopsy Specimen><Bp50><Breast Cancer><Breast Cancer Model><Breast Neoplasms><Breast Tumors><Breast tumor model><CD115><CD115 Gene><CD274><CD40><CD8 Cell><CD8 T cells><CD8 lymphocyte><CD8+ T cell><CD8+ T-Lymphocyte><CD8-Positive Lymphocytes><CD8-Positive T-Lymphocytes><CDW40><CSF1R><CSF1R gene><CSFMR><Cancers><Cell Communication and Signaling><Cell Function><Cell Physiology><Cell Process><Cell Signaling><Cell Survival><Cell Viability><Cell-Mediated Lympholytic Cells><Cellular Function><Cellular Physiology><Cellular Process><Clinical><Clinical Data><Clinical Trials><Colony Stimulating Factor 1 Receptor Gene><Complex><Cyclicity><Cytolytic T-Cell><Cytotoxic T Cell><Cytotoxic T-Lymphocytes><DNA Damage><DNA Damage Repair><DNA Injury><DNA Repair><DNA Repair Inhibition><Data><Dendritic Cells><Disease><Disorder><Early-Stage Clinical Trials><Enrollment><GEM model><GEMM model><Gene Transcription><Genetic Transcription><Genetically Engineered Mouse><Goals><Human><Immune infiltrates><Immune response><Immunochemical Immunologic><Immunocompetent><Immunofluorescence><Immunofluorescence Immunologic><Immunologic><Immunologic Subtyping><Immunological><Immunologically><Immunologics><Immunomodulation><Immunophenotyping><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><Infiltration><Intracellular Communication and Signaling><Lead><Lipids><MGC9013><Macrophage><Macrophage Activation><Malignant Breast Neoplasm><Malignant Neoplasms><Malignant Tumor><Mammary Cancer><Mammary Neoplasms><Mediating><Medical><Metabolic><Mice><Mice Mammals><Modeling><Modern Man><Murine><Mus><Myeloid Cells><Mφ><Nature><PALB2><PALB2 gene><PARP Inhibitor><PARP inhibition><PARP-1 inhibitor><PARPi><PD 1><PD-1><PD-1 antibody><PD-L1><PD1><PD1 antibody><PDL-1><Pathway interactions><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Pb element><Periodicity><Phase 1 Clinical Trials><Phase I Clinical Trials><Phenotype><Pilot Projects><Poly(ADP-ribose) Polymerase Inhibitor><Poly(ADP-ribose) polymerase 1 inhibitor><Polymerase><Population><Pre-Clinical Model><Preclinical Models><Preclinical data><Programmed Cell Death 1 Ligand 1><Programmed Death Ligand 1><RNA Expression><Resistance><Rhythmicity><Sampling><Signal Transduction><Signal Transduction Systems><Signaling><Stimulator of Interferon Genes><Subcellular Process><T cell response><T-Cell Activation><T-Cells><T-Lymphocyte><T8 Cells><T8 Lymphocytes><TNBC><TNFRSF5><TNFRSF5 gene><Testing><Therapeutic><Training><Transcription><Tumor Cell><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><Tumor-Derived><Tumor-associated macrophages><Unscheduled DNA Synthesis><Veiled Cells><Work><aPD-1><aPD1><activate T cells><advanced breast cancer><advanced stage breast cancer><anti programmed cell death 1><anti-PD-1><anti-PD-1 Ab><anti-PD-1 antibodies><anti-PD-1 monoclonal antibodies><anti-PD1><anti-PD1 Ab><anti-PD1 antibodies><anti-PD1 monoclonal antibodies><anti-programmed cell death protein 1><anti-programmed cell death protein 1 antibodies><anti-programmed death-1 antibody><anti-tumor response><antiPD-1><biological signal transduction><brca gene><c-FMS><c-fms Genes><c-fms Proto-Oncogenes><cGAMP STING><cGAMP-STING><cGAMP/STING><cGAS/STING><cancer microenvironment><clinical relevance><clinically relevant><cyclic GMP-AMP synthase/STING><determine efficacy><early clinical trial><early phase clinical trial><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><efficacy study><enroll><evaluate efficacy><examine efficacy><genetically engineered mouse model><genetically engineered murine model><heavy metal Pb><heavy metal lead><homologous recombination deficiency><homologous recombination repair deficiency><host response><immune cell infiltrate><immune competent><immune microenvironment><immune modulation><immune regulation><immune suppression><immune suppressive activity><immune suppressive function><immune suppressive macrophages><immune system response><immunologic reactivity control><immunomodulatory><immunoregulation><immunoregulatory><immunoresponse><immunosuppressive activity><immunosuppressive function><immunosuppressive macrophages><immunosuppressive microenvironment><immunosuppressive response><immunosuppressive tumor microenvironment><improved outcome><in vivo><inhibitor><inhibitor drug><inhibitor therapeutic><inhibitor therapy><killer T cell><malignancy><malignant breast tumor><mammary cancer model><mammary tumor><mammary tumor model><mouse model><murine model><neoplasm/cancer><neoplastic cell><p50><participant enrollment><partner and localizer of BRCA2><pathway><patient enrollment><patient oriented outcomes><phase I protocol><pilot study><pre-clinical><preclinical><preclinical findings><preclinical information><programmed cell death 1><programmed cell death ligand 1><programmed cell death protein 1><programmed cell death protein ligand 1><programmed death 1><protein death-ligand 1><recruit><resistance mechanism><resistant><resistant mechanism><response><scRNA sequencing><scRNA-seq><single cell RNA-seq><single cell RNAseq><single cell expression profiling><single cell transcriptomic profiling><single-cell RNA sequencing><sle2><spatial relationship><synergism><synthetic lethal interaction><synthetic lethality><systemic lupus erythematosus susceptibility 2><thymus derived lymphocyte><triple-negative breast cancer><triple-negative invasive breast carcinoma><tumor><tumor growth><tumor immune microenvironment><tumor microenvironment><tumor-immune system interactions><αPD-1><αPD1>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Geoffrey I. Shapiro

BRIGHAM AND WOMEN'S HOSPITAL, BOSTON, MA

High-opportunity lead · 74/100
Likely hiring
Above-average budget
Very recent
Active award
$772,208
FY 2026

Project Title

Macrophage-directed strategies for BRCA-associated breast cancer

Grant Number:

1R01CA307291-01

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/10/2026

End Date:

3/31/2031

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY Poly (ADP-ribose) polymerase inhibitors (PARPi’s) are a promising treatment for BRCA-associated breast cancer, exerting synthetic lethal effects in homologous recombination (HR) repair-deficient tumor cells, yet clinical results are not durable. Our team has demonstrated that PARPi-m...

Research Terms

<Address><Agonist><Antibodies><Antitumor Response><B7-H1><BRCA 1/2><BRCA deficient><BRCA1/2><Biology><Biopsy><Biopsy Sample><Biopsy Specimen><Bp50><Breast Cancer><Breast Cancer Model><Breast Neoplasms><Breast Tumors><Breast tumor model><CD115><CD115 Gene><CD274><CD40><CD8 Cell><CD8 T cells><CD8 lymphocyte><CD8+ T cell><CD8+ T-Lymphocyte><CD8-Positive Lymphocytes><CD8-Positive T-Lymphocytes><CDW40><CSF1R><CSF1R gene><CSFMR><Cancers><Cell Communication and Signaling><Cell Function><Cell Physiology><Cell Process><Cell Signaling><Cell Survival><Cell Viability><Cell-Mediated Lympholytic Cells><Cellular Function><Cellular Physiology><Cellular Process><Clinical><Clinical Data><Clinical Trials><Colony Stimulating Factor 1 Receptor Gene><Complex><Cyclicity><Cytolytic T-Cell><Cytotoxic T Cell><Cytotoxic T-Lymphocytes><DNA Damage><DNA Damage Repair><DNA Injury><DNA Repair><DNA Repair Inhibition><Data><Dendritic Cells><Disease><Disorder><Early-Stage Clinical Trials><Enrollment><GEM model><GEMM model><Gene Transcription><Genetic Transcription><Genetically Engineered Mouse><Goals><Human><Immune infiltrates><Immune response><Immunochemical Immunologic><Immunocompetent><Immunofluorescence><Immunofluorescence Immunologic><Immunologic><Immunologic Subtyping><Immunological><Immunologically><Immunologics><Immunomodulation><Immunophenotyping><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><Infiltration><Intracellular Communication and Signaling><Lead><Lipids><MGC9013><Macrophage><Macrophage Activation><Malignant Breast Neoplasm><Malignant Neoplasms><Malignant Tumor><Mammary Cancer><Mammary Neoplasms><Mediating><Medical><Metabolic><Mice><Mice Mammals><Modeling><Modern Man><Murine><Mus><Myeloid Cells><Mφ><Nature><PALB2><PALB2 gene><PARP Inhibitor><PARP inhibition><PARP-1 inhibitor><PARPi><PD 1><PD-1><PD-1 antibody><PD-L1><PD1><PD1 antibody><PDL-1><Pathway interactions><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Pb element><Periodicity><Phase 1 Clinical Trials><Phase I Clinical Trials><Phenotype><Pilot Projects><Poly(ADP-ribose) Polymerase Inhibitor><Poly(ADP-ribose) polymerase 1 inhibitor><Polymerase><Population><Pre-Clinical Model><Preclinical Models><Preclinical data><Programmed Cell Death 1 Ligand 1><Programmed Death Ligand 1><RNA Expression><Resistance><Rhythmicity><Sampling><Signal Transduction><Signal Transduction Systems><Signaling><Stimulator of Interferon Genes><Subcellular Process><T cell response><T-Cell Activation><T-Cells><T-Lymphocyte><T8 Cells><T8 Lymphocytes><TNBC><TNFRSF5><TNFRSF5 gene><Testing><Therapeutic><Training><Transcription><Tumor Cell><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><Tumor-Derived><Tumor-associated macrophages><Unscheduled DNA Synthesis><Veiled Cells><Work><aPD-1><aPD1><activate T cells><advanced breast cancer><advanced stage breast cancer><anti programmed cell death 1><anti-PD-1><anti-PD-1 Ab><anti-PD-1 antibodies><anti-PD-1 monoclonal antibodies><anti-PD1><anti-PD1 Ab><anti-PD1 antibodies><anti-PD1 monoclonal antibodies><anti-programmed cell death protein 1><anti-programmed cell death protein 1 antibodies><anti-programmed death-1 antibody><anti-tumor response><antiPD-1><biological signal transduction><brca gene><c-FMS><c-fms Genes><c-fms Proto-Oncogenes><cGAMP STING><cGAMP-STING><cGAMP/STING><cGAS/STING><cancer microenvironment><clinical relevance><clinically relevant><cyclic GMP-AMP synthase/STING><determine efficacy><early clinical trial><early phase clinical trial><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><efficacy study><enroll><evaluate efficacy><examine efficacy><genetically engineered mouse model><genetically engineered murine model><heavy metal Pb><heavy metal lead><homologous recombination deficiency><homologous recombination repair deficiency><host response><immune cell infiltrate><immune competent><immune microenvironment><immune modulation><immune regulation><immune suppression><immune suppressive activity><immune suppressive function><immune suppressive macrophages><immune system response><immunologic reactivity control><immunomodulatory><immunoregulation><immunoregulatory><immunoresponse><immunosuppressive activity><immunosuppressive function><immunosuppressive macrophages><immunosuppressive microenvironment><immunosuppressive response><immunosuppressive tumor microenvironment><improved outcome><in vivo><inhibitor><inhibitor drug><inhibitor therapeutic><inhibitor therapy><killer T cell><malignancy><malignant breast tumor><mammary cancer model><mammary tumor><mammary tumor model><mouse model><murine model><neoplasm/cancer><neoplastic cell><p50><participant enrollment><partner and localizer of BRCA2><pathway><patient enrollment><patient oriented outcomes><phase I protocol><pilot study><pre-clinical><preclinical><preclinical findings><preclinical information><programmed cell death 1><programmed cell death ligand 1><programmed cell death protein 1><programmed cell death protein ligand 1><programmed death 1><protein death-ligand 1><recruit><resistance mechanism><resistant><resistant mechanism><response><scRNA sequencing><scRNA-seq><single cell RNA-seq><single cell RNAseq><single cell expression profiling><single cell transcriptomic profiling><single-cell RNA sequencing><sle2><spatial relationship><synergism><synthetic lethal interaction><synthetic lethality><systemic lupus erythematosus susceptibility 2><thymus derived lymphocyte><triple-negative breast cancer><triple-negative invasive breast carcinoma><tumor><tumor growth><tumor immune microenvironment><tumor microenvironment><tumor-immune system interactions><αPD-1><αPD1>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

JULI FEIGON

UNIVERSITY OF CALIFORNIA LOS ANGELES, LOS ANGELES, CA

High-opportunity lead · 74/100
Likely hiring
Above-average budget
Very recent
Active award
$695,218
FY 2026

Project Title

Structural biology of telomerase and telomeres

Grant Number:

5R35GM131901-08

Activity Code:

R35

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2019

End Date:

3/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary/Abstract Telomeres, the physical ends of linear chromosomes, are composed of short repeating sequences (TTGGGG in the G-strand for Tetrahymena thermophila and TTAGGG in human) of double-strand DNA with a single-strand 3′ overhang of the G-strand and, in humans, six proteins collectiv...

Research Terms

<Affect><Aging><Aplastic Anemia><Binding><Biochemistry><Biological Chemistry><Biology><Bp50><CD40><CDW40><Chromosomes><Coats plus disease><Coats plus syndrome><Cole syndrome><Cole-Rauschkolb-Toomey syndrome><Complex><Cryo-electron Microscopy><Cryoelectron Microscopy><DNA><DNA Molecular Biology><DNA Primase><DNA mutation><DNA polymerase alpha-primase><DNA polymerase α-primase><Deoxyribonucleic Acid><Disease><Disorder><Double-Stranded DNA><Drug Targeting><Dyskeratosis Congenita><Dysmyelopoietic Syndromes><EC 2.7.7.49><Electron Cryomicroscopy><Engman syndrome><Genetic Change><Genetic defect><Genetic mutation><Goals><Health><Human><In Situ><Lung Tissue Fibrosis><MGC9013><Modern Man><Molecular Biology><Molecular Interaction><Mutation><Myelodysplastic Disease><Myelodysplastic Syndromes><NMR Spectrometer><NMR Spectroscopy><Oncogenesis><Organism><Polymerase><Primase><Proteins><Pulmonary Fibrosis><RNA Transcriptase><RNA-Dependent DNA Polymerase><RNA-Directed DNA Polymerase><Refractory Anemia with an Excess of Blasts><Refractory anaemia with excess blasts><Regulation><Research><Reverse Transcriptase><Revertase><Smoldering Leukemia><Structure><TNFRSF5><TNFRSF5 gene><Telomerase><Tetrahymena><Tetrahymena thermophila><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><Visualization><X-Linked Dyskeratosis Congenita><Zinsser syndrome><Zinsser-Engman-Cole syndrome><congenital dyskeratosis><cryo-EM><cryoEM><cryogenic electron microscopy><ds-DNA><dsDNA><fibrosis in the lung><genome mutation><living system><lung fibrosis><myelodysplasia><nuclear magnetic resonance spectroscopy><p50><particle><progenitor cell division><progenitor cell renewal><progenitor division><progenitor renewal><protein complex><recruit><stem and progenitor cell division><stem and progenitor cell renewal><stem cell division><stem cell renewal><structural biology><telomere><tumorigenesis>
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Hirofumi Morishita

ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NEW YORK, NY

High-opportunity lead · 74/100
Likely hiring
Above-average budget
Very recent
Active award
$665,667
FY 2026

Project Title

Maturation of frontal cortico-thalamic circuitry in control of social behavior

Grant Number:

5R01MH118297-08

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

7/18/2019

End Date:

3/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Impaired social processing is one of key hallmarks of many neurodevelopmental and psychiatric disorders including autism spectrum disorders (ASDs). As the social deficits tend to emerge during early childhood and adolescence, characterization of developmental trajectories is vastly important for und...

Research Terms

<12-20 years old><21+ years old><ASD><Address><Adolescence><Adolescent><Adolescent Youth><Adult><Adult Human><Affect><Alternative Therapies><Alternative intervention><Animals><Autism><Autistic Disorder><Behavior><Behavioral><Benzodiazepine Compounds><Benzodiazepines><Bp50><Brain region><CD40><CDW40><Cell Communication and Signaling><Cell Signaling><Data><Development><Disease><Disorder><Drug Therapy><Early Infantile Autism><Electrophysiology><Electrophysiology (science)><Female><Fiber><Funding><Genes><Genetic><Genetic Risk><Genetic predisposing factor><Housing><Image><Impairment><Infantile Autism><Intervention><Intracellular Communication and Signaling><Kanner's Syndrome><Link><MGC9013><Measures><Medial><Mental disorders><Mental health disorders><Mice><Mice Mammals><Murine><Mus><Nerve Cells><Nerve Unit><Neural Cell><Neurocyte><Neurodevelopmental Disorder><Neurological Development Disorder><Neurons><Neurophysiology / Electrophysiology><Paraventricular Nucleus of Thalamus><Paraventricular Thalamic Nucleus><Partner in relationship><Pathway interactions><Pharmacological Treatment><Pharmacotherapy><Photometry><Prefrontal Cortex><Prevention><Psychiatric Disease><Psychiatric Disorder><Signal Transduction><Signal Transduction Systems><Signaling><Social Behavior><Social Controls><Social Interaction><Social Responsibility><Social isolation><Structure of paraventricular nucleus of thalamus><TNFRSF5><TNFRSF5 gene><Techniques><Testing><Thalamic structure><Thalamus><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><adolescence (12-20)><adulthood><autism spectral disorder><autism spectrum disorder><autistic spectrum disorder><biological signal transduction><developmental><disease risk><disorder risk><drug intervention><drug treatment><early adolescence><early childhood><electrophysiological><experience><genetic risk factor><global gene expression><global transcription profile><imaging><in vivo><inherited factor><juvenile><juvenile human><later in life><later life><male><mate><mental illness><neurodevelopmental disease><neuronal><optogenetics><p50><patch clamp><pathway><pharmaceutical intervention><pharmacologic><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><prevent><preventing><psychiatric illness><psychological disorder><reward circuitry><social><social defects><social deficits><social disorders><social dysfunction><sociobehavior><sociobehavioral><thalamic><therapeutic target><transcriptome><♀><♂>
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Coleman Drake

UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PITTSBURGH, PA

High-opportunity lead · 74/100
Likely hiring
Above-average budget
Very recent
Active award
$649,620
FY 2026

Project Title

Medicare Advantage and cancer care for older adults

Grant Number:

1R01CA306909-01

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/1/2026

End Date:

4/30/2031

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY/ABSTRACT Over 40% of adults in the United States will develop cancer in their lifetime, with 58% of new cancer cases occurring in individuals ages 65 and over. While this age group is nearly universally insured through Medicare, they may face insurance-related barriers to care due to...

Research Terms

<21+ years old><65 and older><65 or older><65 years of age and older><65 years of age or more><65 years of age or older><65+ years><65+ years old><> 65 years><Access to Care><Accreditation><Address><Adult><Adult Human><Affect><Aged 65 and Over><American College of Surgeons><Area><Breast><Cancer Burden><Cancer Center><Cancer Hospital><Cancer Treatment><Cancers><Caring><Characteristics><Clinical Oncology><Clinical Trials><Colon or Rectum><Colorectal><Complex><Data><Data Sources><Diagnosis><Enrollment><Exclusion><Face><Fee-for-Service Plans><Fees for Service><Geography><Goals><Guidelines><Health><Health Care><Health Insurance><Health Insurance for Aged and Disabled, Title 18><Health Insurance for Disabled Title 18><Health Services><Health Services Accessibility><Health Services Evaluation><Health Services Research><Health system><High-Risk Cancer><Hospitals><Improve Access><Individual><Insurance><Insurance Carriers><Insurers><Investigators><Link><Literature><Lung><Lung Respiratory System><Malignant Neoplasm Therapy><Malignant Neoplasm Treatment><Malignant Neoplasms><Malignant Tumor><Medical Care Research><Medicare><Medicare claim><Methods><Modality><NCI Organization><National Cancer Burden><National Cancer Institute><Oncology><Oncology Cancer><Operative Procedures><Operative Surgical Procedures><Out-of-Pocket Expense><Outcome><P50 Mechanism><P50 Program><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Pattern><Population><Privatization><Prostate><Prostate Gland><Prostatic Gland><Provider><Publications><QOC><Quality of Care><Quasi-experiment><Quasi-experimental analysis><Quasi-experimental approach><Quasi-experimental design><Quasi-experimental methods><Quasi-experimental research><Quasi-experimental study><Quasi-experimental technique><Radiation><Research><Research Personnel><Researchers><SEER Program><SEER-Surveillance, Epidemiology, and End Results><SYS-TX><Scientific Publication><Specialist><Specialized Center><Specialty><Surgical><Surgical Interventions><Surgical Procedure><Surveillance, Epidemiology and End Results><Surveillance, Epidemiology, and End Results Program><Systemic Therapy><Texas><Time><Title 18><Uncovered Medical Expenses><Uncovered Uninsured Medical Expense><Uninsured Medical Expense><United States><Work><above age 65><access to health services><access to services><access to treatment><accessibility to health services><accredited><adulthood><after age 65><age 65 and greater><age 65 and older><age 65 or older><age > 65><age group><age of 65 years onward><aged 65 and greater><aged 65+><aged ≥65><anti-cancer therapy><availability of services><barrier to care><barrier to health care><barrier to treatment><beneficiary><cancer care><cancer diagnosis><cancer registry><cancer therapy><cancer type><cancer-directed therapy><care access><care providers><colorectum><conference><convention><data registry><econometrics><enroll><faces><facial><health economics><health insurance for disabled><health insurance plan><health service access><health services availability><human old age (65+)><insurance plan><malignancy><medical expenses not covered by insurance><medical specialties><mortality><multi-modality><multimodality><neoplasm registry><neoplasm/cancer><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><obstacle to care><obstacle to health care><older adult><older adulthood><out-of-pocket costs><out-of-pocket health care costs><over 65 years><patient oriented outcomes><patient population><patient subclass><patient subcluster><patient subgroups><patient subpopulations><patient subsets><patient subtypes><payment><population based><provider networks><rapid growth><service availability><services research><summit><surgery><symposia><symposium><total medical expenditure><treatment access><treatment and outcome><trend><≥65 years>
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Lindsay Marie Sabik

UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PITTSBURGH, PA

High-opportunity lead · 74/100
Likely hiring
Above-average budget
Very recent
Active award
$649,620
FY 2026

Project Title

Medicare Advantage and cancer care for older adults

Grant Number:

1R01CA306909-01

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/1/2026

End Date:

4/30/2031

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY/ABSTRACT Over 40% of adults in the United States will develop cancer in their lifetime, with 58% of new cancer cases occurring in individuals ages 65 and over. While this age group is nearly universally insured through Medicare, they may face insurance-related barriers to care due to...

Research Terms

<21+ years old><65 and older><65 or older><65 years of age and older><65 years of age or more><65 years of age or older><65+ years><65+ years old><> 65 years><Access to Care><Accreditation><Address><Adult><Adult Human><Affect><Aged 65 and Over><American College of Surgeons><Area><Breast><Cancer Burden><Cancer Center><Cancer Hospital><Cancer Treatment><Cancers><Caring><Characteristics><Clinical Oncology><Clinical Trials><Colon or Rectum><Colorectal><Complex><Data><Data Sources><Diagnosis><Enrollment><Exclusion><Face><Fee-for-Service Plans><Fees for Service><Geography><Goals><Guidelines><Health><Health Care><Health Insurance><Health Insurance for Aged and Disabled, Title 18><Health Insurance for Disabled Title 18><Health Services><Health Services Accessibility><Health Services Evaluation><Health Services Research><Health system><High-Risk Cancer><Hospitals><Improve Access><Individual><Insurance><Insurance Carriers><Insurers><Investigators><Link><Literature><Lung><Lung Respiratory System><Malignant Neoplasm Therapy><Malignant Neoplasm Treatment><Malignant Neoplasms><Malignant Tumor><Medical Care Research><Medicare><Medicare claim><Methods><Modality><NCI Organization><National Cancer Burden><National Cancer Institute><Oncology><Oncology Cancer><Operative Procedures><Operative Surgical Procedures><Out-of-Pocket Expense><Outcome><P50 Mechanism><P50 Program><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Pattern><Population><Privatization><Prostate><Prostate Gland><Prostatic Gland><Provider><Publications><QOC><Quality of Care><Quasi-experiment><Quasi-experimental analysis><Quasi-experimental approach><Quasi-experimental design><Quasi-experimental methods><Quasi-experimental research><Quasi-experimental study><Quasi-experimental technique><Radiation><Research><Research Personnel><Researchers><SEER Program><SEER-Surveillance, Epidemiology, and End Results><SYS-TX><Scientific Publication><Specialist><Specialized Center><Specialty><Surgical><Surgical Interventions><Surgical Procedure><Surveillance, Epidemiology and End Results><Surveillance, Epidemiology, and End Results Program><Systemic Therapy><Texas><Time><Title 18><Uncovered Medical Expenses><Uncovered Uninsured Medical Expense><Uninsured Medical Expense><United States><Work><above age 65><access to health services><access to services><access to treatment><accessibility to health services><accredited><adulthood><after age 65><age 65 and greater><age 65 and older><age 65 or older><age > 65><age group><age of 65 years onward><aged 65 and greater><aged 65+><aged ≥65><anti-cancer therapy><availability of services><barrier to care><barrier to health care><barrier to treatment><beneficiary><cancer care><cancer diagnosis><cancer registry><cancer therapy><cancer type><cancer-directed therapy><care access><care providers><colorectum><conference><convention><data registry><econometrics><enroll><faces><facial><health economics><health insurance for disabled><health insurance plan><health service access><health services availability><human old age (65+)><insurance plan><malignancy><medical expenses not covered by insurance><medical specialties><mortality><multi-modality><multimodality><neoplasm registry><neoplasm/cancer><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><obstacle to care><obstacle to health care><older adult><older adulthood><out-of-pocket costs><out-of-pocket health care costs><over 65 years><patient oriented outcomes><patient population><patient subclass><patient subcluster><patient subgroups><patient subpopulations><patient subsets><patient subtypes><payment><population based><provider networks><rapid growth><service availability><services research><summit><surgery><symposia><symposium><total medical expenditure><treatment access><treatment and outcome><trend><≥65 years>
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Benjamin Elison Gewurz

BRIGHAM AND WOMEN'S HOSPITAL, BOSTON, MA

High-opportunity lead · 74/100
Likely hiring
Above-average budget
Very recent
Active award
$606,138
FY 2026

Project Title

Epstein-Barr virus LMP1 mediated oncogenicity

Grant Number:

5R01CA228700-07

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/19/2019

End Date:

3/31/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Abstract Epstein-Barr virus (EBV) is highly associated with multiple types of lymphomas, which occur at elevated frequencies in people living with HIV. These include Hodgkin, Burkitt, post- transplant, plasmablastic, primary central nervous system and diffuse large B-cell lymphomas, which cause a l...

Research Terms

<21+ years old><AIDS><AIDS Virus><AIDS lymphoma><AIDS-Associated Lymphoma><AIDS-Related Lymphoma><Acquired Immune Deficiency><Acquired Immune Deficiency Syndrome><Acquired Immune Deficiency Syndrome Virus><Acquired Immunodeficiency Syndrome><Acquired Immunodeficiency Syndrome Virus><Adult><Adult Human><Advanced HIV><Anti-HIV Positivity><Antigen Presentation><Apoptosis><Apoptosis Pathway><B Cell Proliferation><B blood cells><B cell><B cell immortalization><B cells><B lymphocyte immortalization><B-Cell Development><B-Cells><B-Lymphocytes><B-cell><B7-H1><Bp50><Burkitt Herpesvirus><Burkitt Lymphoma Virus><C-terminal><CD274><CD4 Cells><CD4 Positive T Lymphocytes><CD4 T cells><CD4 helper T cell><CD4 lymphocyte><CD4+ T-Lymphocyte><CD4-Positive Lymphocytes><CD40><CDW40><CNS Nervous System><Cancer Cause><Cancer Etiology><Cancer Genes><Cancer-Promoting Gene><Cancerous><Cancers><Cell Body><Cell Communication and Signaling><Cell Compartmentation><Cell Compartmentations><Cell Differentiation><Cell Differentiation process><Cell Signaling><Cell model><Cells><Cellular Expansion><Cellular Growth><Cellular model><Central Nervous System><Clinical><DLBCL><Data><Dependence><Diffuse Immunoblastic Lymphosarcoma><Diffuse Large B-Cell Lymphoma><EB virus><EBV><EBV LMP-1 protein><EBV LMP1 protein><EBV associated lymphoma><EBV induced lymphoma><EBV latency><EBV lymphoma><EBV malignancies><EBV(+) lymphoma><EBV(+) malignancy><EBV+ lymphoma><EBV+ve lymphoma><EBV-Related Malignancy><EBV-associated cancers><EBV-associated malignancy><EBV-positive cancer><EBV-positive lymphomas><EBV-positive malignancy><EBV-positive malignant tumor><EBV-related cancer><EBV-related lymphoma><Epstein Barr Virus><Epstein Barr Virus Associated Lymphoma><Epstein Barr Virus Lymphoma><Epstein Barr Virus Malignancy><Epstein Barr Virus associated cancers><Epstein Barr Virus driven lymphoma><Epstein Barr Virus positive cancer><Epstein Barr induced lymphoma><Epstein-Barr Virus associated malignancy><Epstein-Barr Virus latency><Epstein-Barr Virus-Related Lymphoma><Epstein-Barr Virus-Related Malignancy><Epstein-Barr Virus-Related Malignant Neoplasm><Epstein-Barr virus LMP-1 protein><Epstein-Barr virus latent membrane protein 1><Foundations><Frequencies><Gene Expression><Germinal Center><Germinoblastic Sarcoma><Germinoblastoma><HAART><HHV-4><HHV4><HIV><HIV Associated Lymphoma><HIV Lymphoma><HIV Positive><HIV Positivity><HIV Seroconversion><HIV Seropositivity><HIV antibody positive><HIV individuals><HIV infected individuals><HIV infected persons><HIV people><HIV positive individuals><HIV positive people><HIV+><HIV-Related Lymphoma><HTLV-III Seroconversion><HTLV-III Seropositivity><Highly Active Antiretroviral Therapy><Hodgkin Disease><Hodgkin Disorder><Hodgkin lymphoma><Hodgkin's><Hodgkin's Lymphoma><Hodgkin's disease><Hodgkins lymphoma><Human><Human Herpesvirus 4><Human Immunodeficiency Viruses><Immune system><Immunoblastic Lymphoma><Immunoblastic Sarcoma><Immunoblastoma><Infection><Infectious Mononucleosis Virus><Intracellular Communication and Signaling><LAV-HTLV-III><Large-Cell Immunoblastic Lymphoma><Learning><Lymphadenopathy-Associated Virus><Lymphatic cell><Lymphocyte><Lymphocytic><Lymphoid><Lymphoma><Lymphomagenesis><MGC9013><Malignant Lymphogranuloma><Malignant Lymphoma><Malignant Neoplasms><Malignant Tumor><Mediating><Membrane Protein Gene><Membrane Proteins><Membrane-Associated Proteins><Memory B Cell><Memory B-Lymphocyte><Mice><Mice Mammals><Modeling><Modern Man><Murine><Mus><NT mimic 1><Neuraxis><Oncogenes><Oncogenic><Organoids><PD-L1><PDL-1><PLWH><PWH><Pathogenicity><Pathway interactions><Plasmablastic Lymphoma><Population><Programmed Cell Death><Programmed Cell Death 1 Ligand 1><Programmed Death Ligand 1><Proteomics><Receptor Protein><Recombinants><Reticulolymphosarcoma><Risk><Role><Series><Severe HIV Disease><Signal Transduction><Signal Transduction Systems><Signaling><Structure><Structure of germinal center of lymph node><Surface Proteins><T-Cells><T-Lymphocyte><T4 Cells><T4 Lymphocytes><TNFRSF5><TNFRSF5 gene><Tail><Testing><Tonsil><Transforming Genes><Tumor Cell><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><Viral reservoir><Virus reservoir><Virus-HIV><adulthood><biological signal transduction><burden of disease><burden of illness><cell growth><cell transformation><cellular differentiation><check point blockade><checkpoint blockade><co-infection><coinfection><cytokine><disease burden><highly active antiretroviral treatment><humanized mice><humanized mouse><immune check point blockade><immune checkpoint blockade><individuals infected with HIV><individuals with HIV><individuals with human immunodeficiency virus><infected B cell><infected B lymphocyte><large cell Diffuse non-Hodgkin's lymphoma><latent membrane protein 1, Human herpesvirus 4><lymph cell><malignancy><mimic 1><mouse model><murine model><mutant><neoplasm/cancer><neoplastic cell><neurotensin mimic 1><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><p50><pathway><people infected with HIV><people infected with human immunodeficiency virus><people living with HIV><people with HIV><people with human immunodeficiency virus><peripheral blood><post-transplant><post-transplantation><posttransplant><posttransplantation><programmed cell death ligand 1><programmed cell death protein ligand 1><programs><protein death-ligand 1><public health relevance><receptor><response><social role><thymus derived lymphocyte><tonsillar><transformed cells>
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Devon A. Lawson

UNIVERSITY OF CALIFORNIA-IRVINE, IRVINE, CA

High-opportunity lead · 74/100
Likely hiring
Above-average budget
Very recent
Active award
$554,732
FY 2026

Project Title

Immune microenvironment in brain metastais

Grant Number:

2R01CA237376-06A1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/8/2026

End Date:

4/30/2031

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary/Abstract Brain metastasis is a lethal disease and major clinical unmet need for breast cancer patients. There is growing interest in immunotherapies to treat central nervous system (CNS) cancers, but greater understanding of the unique immune microenvironment of the brain is needed t...

Research Terms

<2aR phosphoprotein I><2ar peptide><Agonist><Animals><Antigen Presentation><Assay><Autoregulation><Binding><Bioassay><Biological Assay><Blood monocyte><Body Tissues><Bone Marrow><Bone Marrow Reticuloendothelial System><Bp50><Brain><Brain Diseases><Brain Disorders><Brain Metastasis><Brain Neoplasia><Brain Neoplasms><Brain Nervous System><Brain Tumors><Breast Cancer><Breast Cancer Patient><Breast Tumor Patient><CD40><CD8 Cell><CD8 T cells><CD8 lymphocyte><CD8+ T cell><CD8+ T-Lymphocyte><CD8-Positive Lymphocytes><CD8-Positive T-Lymphocytes><CDW40><CNS Cancer><CNS Nervous System><Cell Body><Cell Communication><Cell Communication and Signaling><Cell Function><Cell Interaction><Cell Physiology><Cell Process><Cell Signaling><Cell-to-Cell Interaction><Cells><Cellular Function><Cellular Physiology><Cellular Process><Cellular biology><Central Nervous System><Central Nervous System Cancer><Chemotaxis><Chickens><Clinical><Development><Disease><Disease Progression><Disorder><Encephalon><Encephalon Diseases><Eta-1 protein><Eta-1-Op protein><Funding><Gallus domesticus><Gallus gallus><Gallus gallus domesticus><Genetic><Home><Homeostasis><Homing><Hortega cell><Human><Immune><Immune mediated therapy><Immune response><Immunes><Immunologically Directed Therapy><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><Immunotherapy><In Vitro><Infiltration><Inflammatory><Inflammatory Response><Intracellular Communication and Signaling><Intracranial CNS Disorders><Intracranial Central Nervous System Disorders><Knock-out><Knockout><Knowledge><Ligands><MGC9013><Macrophage><Malignant Breast Neoplasm><Malignant CNS Neoplasms><Malignant Cell><Malignant Tumor of the CNS><Malignant Tumor of the Central Nervous System><Malignant neoplasm of central nervous system><Marrow monocyte><Mediating><Mediator><Metastasis><Metastasize><Metastatic Lesion><Metastatic Mass><Metastatic Neoplasm><Metastatic Neoplasm to the Brain><Metastatic Tumor><Metastatic Tumor to the Brain><Metastatic malignant neoplasm to brain><Mice><Mice Mammals><Microglia><Modern Man><Molecular><Molecular Interaction><Murine><Mus><Mφ><Nature><Neoplasm Metastasis><Neuraxis><Patients><Phagocytes><Phagocytic Cell><Phase><Physiological Homeostasis><Play><Population><Prognosis><Purine Receptors><Purinergic Receptors><Purinoceptor><Regulation><Regulatory T-Lymphocyte><Reporting><Role><Secondary Neoplasm><Secondary Tumor><Signal Transduction><Signal Transduction Systems><Signaling><Site><Source><Subcellular Process><System><T cell response><T-Cell Activation><T-Cells><T-Lymphocyte><T8 Cells><T8 Lymphocytes><TNFRSF5><TNFRSF5 gene><Testing><Tissues><Treg><Tumor Immunity><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><Tumor Promotion><Tumor-associated macrophages><Upregulation><Work><activate T cells><adaptive immunity><amebocyte><anti-tumor immune response><anti-tumor immunity><antigen-specific T cells><antitumor immunity><biological signal transduction><bone sialoprotein 1><bone sialoprotein I><brain cell><brain micrometastasis><cancer cell><cancer immunity><cancer metastasis><cancer of the central nervous system><cancer progression><candidate identification><cell biology><conditional knock-out><conditional knockout><developmental><disease control><disorder control><early T-lympocyte activation-1 protein><effective therapy><effective treatment><experiment><experimental research><experimental study><experiments><gitter cell><homes><host response><humanized mice><humanized mouse><immune microenvironment><immune suppression><immune suppressive activity><immune suppressive function><immune system response><immune therapeutic approach><immune therapeutic interventions><immune therapeutic regimens><immune therapeutic strategy><immune therapy><immune-based therapies><immune-based treatments><immuno therapy><immunoresponse><immunosuppressive activity><immunosuppressive function><immunosuppressive microenvironment><immunosuppressive response><immunosuppressive tumor microenvironment><in vivo><individuals with breast cancer><interest><malignant breast tumor><mesoglia><microglial cell><microgliocyte><migration><monocyte><mouse model><murine model><neoplasm progression><neoplastic progression><osteopontin><p50><patients with breast cancer><perivascular glial cell><person with breast cancer><pharmacologic><regulatory T-cells><response><scRNA sequencing><scRNA-seq><secreted phosphoprotein 1><sialoprotein 1><single cell RNA-seq><single cell RNAseq><single cell expression profiling><single cell transcriptomic profiling><single-cell RNA sequencing><social role><therapeutic target><thymus derived lymphocyte><treatment strategy><tumor><tumor cell metastasis><tumor immune microenvironment><tumor progression><tumor-immune system interactions><tumors in the brain>
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Anthony Johnson

MEDICAL COLLEGE OF WISCONSIN, MILWAUKEE, WI

High-opportunity lead · 74/100
Likely hiring
Above-average budget
Very recent
Active award
$546,057
FY 2026

Project Title

Gastroschisis Outcomes of Delivery (GOOD) Study

Grant Number:

5R01HD104607-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/13/2021

End Date:

3/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Gastroschisis is the most common congenital abdominal wall defect in which the intestines herniate outside the fetus into the amniotic fluid. It is diagnosed by prenatal ultrasound after 14 weeks gestation. Approximately 1 out of every 4000 births is affected by gastroschisis, and the incidence is i...

Research Terms

<3rd trimester><Abdomen><Abdominal Delivery><Affect><American><Amniotic Fluid><Antenatal Diagnosis><Aqua Amnii><Birth><Blood><Blood Reticuloendothelial System><Blood Transfusion><C section><Caffeine><Caring><Case Management><Catheters><Caustics><Cesarean><Cesarean section><Chronologic Fetal Maturity><Clinical Data><Clinical Trials><Cognitive><Consensus><Data><Data Bases><Databases><Defect><Development><Diagnosis><Enrollment><Ensure><Enteral><Enteric><Event><Evidence based practice guidelines><Expectancy><Exposure to><Fetal Age><Fetal Body Weight><Fetal Death><Fetal Growth><Fetal Therapies><Fetal Weight><Fetus><Foundations><Futility><Future><Gastroschisis><Gestation><Gestational Age><Goals><High-Risk Pregnancy><Iatrogenesis><Incidence><Individual><Induced Labor><Infant><Infant Mortality><Infant Mortality Total><Infection><Infrastructure><Injury><Institution><Intestinal><Intestinal Atresia><Intestines><Intrauterine Diagnosis><Intravenous Feeding><Intravenous Hyperalimentation><Last Trimester><Length of Stay><Liquor Amnii><Live Birth><Meta-Analysis><Monitor><Morbidity><Mothers><Motor><Necrotizing Enterocolitis><Neonatal><Neonatal Intensive Care Units><Neonatal Mortality><Newborn Intensive Care Units><Number of Days in Hospital><Oligohydramnios><Outcome><P50 Mechanism><P50 Program><Parenteral Feedings><Parenteral Nutrition><Participant><Parturition><Patients><Pattern><Pregnancy><Pregnancy Complications><Pregnant Women><Premature Birth><Prematurely delivering><Prenatal Diagnosis><Preterm Birth><Prolonged Pregnancy><Provider><Publishing><QOL><Quality of life><Randomization trial><Randomized><Recommendation><Registries><Reporting><Research><Research Design><Research Resources><Resources><Retrospective Studies><Risk><Sepsis><Specialized Center><Study Type><Testing><Third Pregnancy Trimester><Third Trimester><Time><United States><Vascular blood supply><Venous><Weight><Woman><abdominal wall><adverse consequence><adverse outcome><airway morbidity><antenatal><antepartum><antepartum diagnosis><arm><biobank><biorepository><birth complications><blood supply><bowel><cohort><comparative effectiveness study><comparative effectiveness trial><complications during pregnancy><constriction><data base><death among infants><death among neonates><death among newborns><death in first year of life><death in infancy><death in infants><death in neonates><death in newborn><death risk><delivery complications><developmental><enroll><evidence based guidelines><evidence based recommendations><expectant mother><expectant women><expecting mother><expecting women><feeding><fetal><fetal surgery><fetus death><fetus surgery><fetus therapy><gastrointestinal><hospital days><hospital length of stay><hospital stay><hyperalimentation><hyperalimentation therapy><iatrogenic><iatrogenically><iatrogenicity><improved outcome><in utero therapy><indexing><individuals who are pregnant><infant death><infant demise><infant morbidity><infantile death><injuries><injury to the intestines><intestinal injury><intra-uterine diagnosis><intra-uterine growth><intrauterine growth><labor induction><mortality among neonates><mortality among newborns><mortality in infants><mortality in neonates><mortality in newborns><mortality risk><neonatal ICU><neonatal death><neonatal demise><neonatal outcome><newborn death><newborn mortality><optimal therapies><optimal treatments><patient subclass><patient subcluster><patient subgroups><patient subpopulations><patient subsets><patient subtypes><people who are pregnant><pregnancy-related complications><pregnant females><pregnant mothers><pregnant people><pregnant populations><premature><premature childbirth><premature delivery><prematurity><prenatal therapy><preterm delivery><primary outcome><prospective><public health research><randomisation><randomization><randomized trial><randomly assigned><respiratory><respiratory morbidity><retrospective research study><retrospective survey><risk mitigation><secondary outcome><stillbirth><stillborn><study design><those who are pregnant><trend><trial design><ultrasound><vascular supply><weights><women who are pregnant>
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Aniko Szabo

MEDICAL COLLEGE OF WISCONSIN, MILWAUKEE, WI

High-opportunity lead · 74/100
Likely hiring
Above-average budget
Very recent
Active award
$546,057
FY 2026

Project Title

Gastroschisis Outcomes of Delivery (GOOD) Study

Grant Number:

5R01HD104607-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/13/2021

End Date:

3/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Gastroschisis is the most common congenital abdominal wall defect in which the intestines herniate outside the fetus into the amniotic fluid. It is diagnosed by prenatal ultrasound after 14 weeks gestation. Approximately 1 out of every 4000 births is affected by gastroschisis, and the incidence is i...

Research Terms

<3rd trimester><Abdomen><Abdominal Delivery><Affect><American><Amniotic Fluid><Antenatal Diagnosis><Aqua Amnii><Birth><Blood><Blood Reticuloendothelial System><Blood Transfusion><C section><Caffeine><Caring><Case Management><Catheters><Caustics><Cesarean><Cesarean section><Chronologic Fetal Maturity><Clinical Data><Clinical Trials><Cognitive><Consensus><Data><Data Bases><Databases><Defect><Development><Diagnosis><Enrollment><Ensure><Enteral><Enteric><Event><Evidence based practice guidelines><Expectancy><Exposure to><Fetal Age><Fetal Body Weight><Fetal Death><Fetal Growth><Fetal Therapies><Fetal Weight><Fetus><Foundations><Futility><Future><Gastroschisis><Gestation><Gestational Age><Goals><High-Risk Pregnancy><Iatrogenesis><Incidence><Individual><Induced Labor><Infant><Infant Mortality><Infant Mortality Total><Infection><Infrastructure><Injury><Institution><Intestinal><Intestinal Atresia><Intestines><Intrauterine Diagnosis><Intravenous Feeding><Intravenous Hyperalimentation><Last Trimester><Length of Stay><Liquor Amnii><Live Birth><Meta-Analysis><Monitor><Morbidity><Mothers><Motor><Necrotizing Enterocolitis><Neonatal><Neonatal Intensive Care Units><Neonatal Mortality><Newborn Intensive Care Units><Number of Days in Hospital><Oligohydramnios><Outcome><P50 Mechanism><P50 Program><Parenteral Feedings><Parenteral Nutrition><Participant><Parturition><Patients><Pattern><Pregnancy><Pregnancy Complications><Pregnant Women><Premature Birth><Prematurely delivering><Prenatal Diagnosis><Preterm Birth><Prolonged Pregnancy><Provider><Publishing><QOL><Quality of life><Randomization trial><Randomized><Recommendation><Registries><Reporting><Research><Research Design><Research Resources><Resources><Retrospective Studies><Risk><Sepsis><Specialized Center><Study Type><Testing><Third Pregnancy Trimester><Third Trimester><Time><United States><Vascular blood supply><Venous><Weight><Woman><abdominal wall><adverse consequence><adverse outcome><airway morbidity><antenatal><antepartum><antepartum diagnosis><arm><biobank><biorepository><birth complications><blood supply><bowel><cohort><comparative effectiveness study><comparative effectiveness trial><complications during pregnancy><constriction><data base><death among infants><death among neonates><death among newborns><death in first year of life><death in infancy><death in infants><death in neonates><death in newborn><death risk><delivery complications><developmental><enroll><evidence based guidelines><evidence based recommendations><expectant mother><expectant women><expecting mother><expecting women><feeding><fetal><fetal surgery><fetus death><fetus surgery><fetus therapy><gastrointestinal><hospital days><hospital length of stay><hospital stay><hyperalimentation><hyperalimentation therapy><iatrogenic><iatrogenically><iatrogenicity><improved outcome><in utero therapy><indexing><individuals who are pregnant><infant death><infant demise><infant morbidity><infantile death><injuries><injury to the intestines><intestinal injury><intra-uterine diagnosis><intra-uterine growth><intrauterine growth><labor induction><mortality among neonates><mortality among newborns><mortality in infants><mortality in neonates><mortality in newborns><mortality risk><neonatal ICU><neonatal death><neonatal demise><neonatal outcome><newborn death><newborn mortality><optimal therapies><optimal treatments><patient subclass><patient subcluster><patient subgroups><patient subpopulations><patient subsets><patient subtypes><people who are pregnant><pregnancy-related complications><pregnant females><pregnant mothers><pregnant people><pregnant populations><premature><premature childbirth><premature delivery><prematurity><prenatal therapy><preterm delivery><primary outcome><prospective><public health research><randomisation><randomization><randomized trial><randomly assigned><respiratory><respiratory morbidity><retrospective research study><retrospective survey><risk mitigation><secondary outcome><stillbirth><stillborn><study design><those who are pregnant><trend><trial design><ultrasound><vascular supply><weights><women who are pregnant>
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BARBARA B WARNER

MEDICAL COLLEGE OF WISCONSIN, MILWAUKEE, WI

High-opportunity lead · 74/100
Likely hiring
Above-average budget
Very recent
Active award
$546,057
FY 2026

Project Title

Gastroschisis Outcomes of Delivery (GOOD) Study

Grant Number:

5R01HD104607-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/13/2021

End Date:

3/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Gastroschisis is the most common congenital abdominal wall defect in which the intestines herniate outside the fetus into the amniotic fluid. It is diagnosed by prenatal ultrasound after 14 weeks gestation. Approximately 1 out of every 4000 births is affected by gastroschisis, and the incidence is i...

Research Terms

<3rd trimester><Abdomen><Abdominal Delivery><Affect><American><Amniotic Fluid><Antenatal Diagnosis><Aqua Amnii><Birth><Blood><Blood Reticuloendothelial System><Blood Transfusion><C section><Caffeine><Caring><Case Management><Catheters><Caustics><Cesarean><Cesarean section><Chronologic Fetal Maturity><Clinical Data><Clinical Trials><Cognitive><Consensus><Data><Data Bases><Databases><Defect><Development><Diagnosis><Enrollment><Ensure><Enteral><Enteric><Event><Evidence based practice guidelines><Expectancy><Exposure to><Fetal Age><Fetal Body Weight><Fetal Death><Fetal Growth><Fetal Therapies><Fetal Weight><Fetus><Foundations><Futility><Future><Gastroschisis><Gestation><Gestational Age><Goals><High-Risk Pregnancy><Iatrogenesis><Incidence><Individual><Induced Labor><Infant><Infant Mortality><Infant Mortality Total><Infection><Infrastructure><Injury><Institution><Intestinal><Intestinal Atresia><Intestines><Intrauterine Diagnosis><Intravenous Feeding><Intravenous Hyperalimentation><Last Trimester><Length of Stay><Liquor Amnii><Live Birth><Meta-Analysis><Monitor><Morbidity><Mothers><Motor><Necrotizing Enterocolitis><Neonatal><Neonatal Intensive Care Units><Neonatal Mortality><Newborn Intensive Care Units><Number of Days in Hospital><Oligohydramnios><Outcome><P50 Mechanism><P50 Program><Parenteral Feedings><Parenteral Nutrition><Participant><Parturition><Patients><Pattern><Pregnancy><Pregnancy Complications><Pregnant Women><Premature Birth><Prematurely delivering><Prenatal Diagnosis><Preterm Birth><Prolonged Pregnancy><Provider><Publishing><QOL><Quality of life><Randomization trial><Randomized><Recommendation><Registries><Reporting><Research><Research Design><Research Resources><Resources><Retrospective Studies><Risk><Sepsis><Specialized Center><Study Type><Testing><Third Pregnancy Trimester><Third Trimester><Time><United States><Vascular blood supply><Venous><Weight><Woman><abdominal wall><adverse consequence><adverse outcome><airway morbidity><antenatal><antepartum><antepartum diagnosis><arm><biobank><biorepository><birth complications><blood supply><bowel><cohort><comparative effectiveness study><comparative effectiveness trial><complications during pregnancy><constriction><data base><death among infants><death among neonates><death among newborns><death in first year of life><death in infancy><death in infants><death in neonates><death in newborn><death risk><delivery complications><developmental><enroll><evidence based guidelines><evidence based recommendations><expectant mother><expectant women><expecting mother><expecting women><feeding><fetal><fetal surgery><fetus death><fetus surgery><fetus therapy><gastrointestinal><hospital days><hospital length of stay><hospital stay><hyperalimentation><hyperalimentation therapy><iatrogenic><iatrogenically><iatrogenicity><improved outcome><in utero therapy><indexing><individuals who are pregnant><infant death><infant demise><infant morbidity><infantile death><injuries><injury to the intestines><intestinal injury><intra-uterine diagnosis><intra-uterine growth><intrauterine growth><labor induction><mortality among neonates><mortality among newborns><mortality in infants><mortality in neonates><mortality in newborns><mortality risk><neonatal ICU><neonatal death><neonatal demise><neonatal outcome><newborn death><newborn mortality><optimal therapies><optimal treatments><patient subclass><patient subcluster><patient subgroups><patient subpopulations><patient subsets><patient subtypes><people who are pregnant><pregnancy-related complications><pregnant females><pregnant mothers><pregnant people><pregnant populations><premature><premature childbirth><premature delivery><prematurity><prenatal therapy><preterm delivery><primary outcome><prospective><public health research><randomisation><randomization><randomized trial><randomly assigned><respiratory><respiratory morbidity><retrospective research study><retrospective survey><risk mitigation><secondary outcome><stillbirth><stillborn><study design><those who are pregnant><trend><trial design><ultrasound><vascular supply><weights><women who are pregnant>
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Amy J Wagner

MEDICAL COLLEGE OF WISCONSIN, MILWAUKEE, WI

High-opportunity lead · 74/100
Likely hiring
Above-average budget
Very recent
Active award
$546,057
FY 2026

Project Title

Gastroschisis Outcomes of Delivery (GOOD) Study

Grant Number:

5R01HD104607-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/13/2021

End Date:

3/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Gastroschisis is the most common congenital abdominal wall defect in which the intestines herniate outside the fetus into the amniotic fluid. It is diagnosed by prenatal ultrasound after 14 weeks gestation. Approximately 1 out of every 4000 births is affected by gastroschisis, and the incidence is i...

Research Terms

<3rd trimester><Abdomen><Abdominal Delivery><Affect><American><Amniotic Fluid><Antenatal Diagnosis><Aqua Amnii><Birth><Blood><Blood Reticuloendothelial System><Blood Transfusion><C section><Caffeine><Caring><Case Management><Catheters><Caustics><Cesarean><Cesarean section><Chronologic Fetal Maturity><Clinical Data><Clinical Trials><Cognitive><Consensus><Data><Data Bases><Databases><Defect><Development><Diagnosis><Enrollment><Ensure><Enteral><Enteric><Event><Evidence based practice guidelines><Expectancy><Exposure to><Fetal Age><Fetal Body Weight><Fetal Death><Fetal Growth><Fetal Therapies><Fetal Weight><Fetus><Foundations><Futility><Future><Gastroschisis><Gestation><Gestational Age><Goals><High-Risk Pregnancy><Iatrogenesis><Incidence><Individual><Induced Labor><Infant><Infant Mortality><Infant Mortality Total><Infection><Infrastructure><Injury><Institution><Intestinal><Intestinal Atresia><Intestines><Intrauterine Diagnosis><Intravenous Feeding><Intravenous Hyperalimentation><Last Trimester><Length of Stay><Liquor Amnii><Live Birth><Meta-Analysis><Monitor><Morbidity><Mothers><Motor><Necrotizing Enterocolitis><Neonatal><Neonatal Intensive Care Units><Neonatal Mortality><Newborn Intensive Care Units><Number of Days in Hospital><Oligohydramnios><Outcome><P50 Mechanism><P50 Program><Parenteral Feedings><Parenteral Nutrition><Participant><Parturition><Patients><Pattern><Pregnancy><Pregnancy Complications><Pregnant Women><Premature Birth><Prematurely delivering><Prenatal Diagnosis><Preterm Birth><Prolonged Pregnancy><Provider><Publishing><QOL><Quality of life><Randomization trial><Randomized><Recommendation><Registries><Reporting><Research><Research Design><Research Resources><Resources><Retrospective Studies><Risk><Sepsis><Specialized Center><Study Type><Testing><Third Pregnancy Trimester><Third Trimester><Time><United States><Vascular blood supply><Venous><Weight><Woman><abdominal wall><adverse consequence><adverse outcome><airway morbidity><antenatal><antepartum><antepartum diagnosis><arm><biobank><biorepository><birth complications><blood supply><bowel><cohort><comparative effectiveness study><comparative effectiveness trial><complications during pregnancy><constriction><data base><death among infants><death among neonates><death among newborns><death in first year of life><death in infancy><death in infants><death in neonates><death in newborn><death risk><delivery complications><developmental><enroll><evidence based guidelines><evidence based recommendations><expectant mother><expectant women><expecting mother><expecting women><feeding><fetal><fetal surgery><fetus death><fetus surgery><fetus therapy><gastrointestinal><hospital days><hospital length of stay><hospital stay><hyperalimentation><hyperalimentation therapy><iatrogenic><iatrogenically><iatrogenicity><improved outcome><in utero therapy><indexing><individuals who are pregnant><infant death><infant demise><infant morbidity><infantile death><injuries><injury to the intestines><intestinal injury><intra-uterine diagnosis><intra-uterine growth><intrauterine growth><labor induction><mortality among neonates><mortality among newborns><mortality in infants><mortality in neonates><mortality in newborns><mortality risk><neonatal ICU><neonatal death><neonatal demise><neonatal outcome><newborn death><newborn mortality><optimal therapies><optimal treatments><patient subclass><patient subcluster><patient subgroups><patient subpopulations><patient subsets><patient subtypes><people who are pregnant><pregnancy-related complications><pregnant females><pregnant mothers><pregnant people><pregnant populations><premature><premature childbirth><premature delivery><prematurity><prenatal therapy><preterm delivery><primary outcome><prospective><public health research><randomisation><randomization><randomized trial><randomly assigned><respiratory><respiratory morbidity><retrospective research study><retrospective survey><risk mitigation><secondary outcome><stillbirth><stillborn><study design><those who are pregnant><trend><trial design><ultrasound><vascular supply><weights><women who are pregnant>
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Alice Oliffson Kamphorst

ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NEW YORK, NY

High-opportunity lead · 74/100
Likely hiring
Above-average budget
Very recent
Active award
$532,970
FY 2026

Project Title

CD4 helper programs that regulate intratumoral immunity

Grant Number:

5R01CA300217-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

4/1/2025

End Date:

3/31/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

SUMMARY Immunotherapies have changed the landscape of cancer treatment, but remain mostly focused on CD8 T cells. In liver cancer patients, we found that in addition to expansion of PD-1+ effector- like CD8 T cells, expansion of CD4 T cells with similarities to follicular helper cells (Tfh) was asso...

Research Terms

<Ab response><Address><Advanced Cancer><Advanced Malignant Neoplasm><Affect><Allergy><Antibodies><Antibody Formation><Antibody Production><Antigen-Presenting Cells><Antitumor Response><Apoptosis><Apoptosis Pathway><Area><Autoimmune Status><Autoimmunity><B blood cells><B cell><B cell differentiation><B cells><B lymphocyte differentiation><B-Cells><B-Lymphocytes><B-cell><BLR1><BLR1 gene><Basal Transcription Factor><Basal transcription factor genes><Biological><Blood Plasma Cell><Body Tissues><Bp50><CD154><CD28><CD28 gene><CD4 Cells><CD4 Positive T Lymphocytes><CD4 T cells><CD4 helper T cell><CD4 lymphocyte><CD4+ T-Lymphocyte><CD4-Positive Lymphocytes><CD40><CD40L><CD40LG><CD8><CD8 Cell><CD8 T cells><CD8 lymphocyte><CD8+ T cell><CD8+ T-Lymphocyte><CD8-Positive Lymphocytes><CD8-Positive T-Lymphocytes><CD8B><CD8B1><CD8B1 gene><CDW40><CXCR-5><CXCR5><Cancer Treatment><Cancers><Cell Body><Cell Communication><Cell Communication and Signaling><Cell Interaction><Cell Signaling><Cell-to-Cell Interaction><Cells><Cholesterol><Chronic><Chronic Disease><Chronic Illness><Class II Genes><Clinical Trials><Data><Dendritic Cells><Frequencies><Gene Transcription><General Transcription Factor Gene><General Transcription Factors><Genetic Transcription><HLA Class II Genes><Helper Cells><Helper T-Cells><Helper T-Lymphocytes><Helper-Inducer T-Cells><Helper-Inducer T-Lymphocyte><Hepatic Cancer><Hepatocarcinoma><Hepatocarcinoma model><Hepatocellular Carcinoma><Hepatocellular cancer><Hepatoma><Hydroxylases><Immune><Immune mediated therapy><Immune response><Immunes><Immunity><Immunologically Directed Therapy><Immunology><Immunotherapy><Inducer Cells><Inducer T-Lymphocytes><Induction Therapy><Infection><Intracellular Communication and Signaling><Investigation><LYT3><Label><Licensing><Liver Cells Carcinoma><Long-term infection><MDR15><MGC9013><MHC Class II><MHC Class II Genes><Malignant Neoplasm Therapy><Malignant Neoplasm Treatment><Malignant Neoplasms><Malignant Tumor><Malignant neoplasm of liver><Maps><Mediating><Medicine><Mixed Function Oxidases><Mixed Function Oxygenases><Molecular><Monooxygenases><NEOADJ><Nature><Neoadjuvant><Neoadjuvant Therapy><Neoadjuvant Treatment><OXYB protein><PD 1><PD-1><PD-1 antibody><PD1><PD1 antibody><Pathway interactions><Patients><Phenotype><Plasma Cells><Plasmacytes><Position><Positioning Attribute><Primary carcinoma of the liver cells><Production><Programmed Cell Death><RNA Expression><Role><Science><Signal Transduction><Signal Transduction Systems><Signaling><T cell factor 1><T cell response><T cell transcription factor 1><T-Cells><T-Lymphocyte><T4 Cells><T4 Lymphocytes><T44><T8 Cells><T8 Lymphocytes><TCF-1 protein><TNFRSF5><TNFRSF5 gene><TNFSF5><TNFSF5 gene><TRAP Gene><Technology><Tissues><Transcription><Transcription Factor Proto-Oncogene><Transcription factor genes><Tumor Cell><Tumor Immunity><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><Vaccination><Veiled Cells><aPD-1><aPD1><accessory cell><anti programmed cell death 1><anti-PD-1><anti-PD-1 Ab><anti-PD-1 antibodies><anti-PD-1 monoclonal antibodies><anti-PD1><anti-PD1 Ab><anti-PD1 antibodies><anti-PD1 monoclonal antibodies><anti-cancer immunotherapy><anti-cancer therapy><anti-programmed cell death protein 1><anti-programmed cell death protein 1 antibodies><anti-programmed death-1 antibody><anti-tumor immune response><anti-tumor immunity><anti-tumor response><antiPD-1><antibody biosynthesis><anticancer immunotherapy><antitumor immunity><biologic><biological signal transduction><cancer immunity><cancer immunotherapy><cancer microenvironment><cancer progression><cancer therapy><cancer type><cancer-directed therapy><chronic disorder><chronic infection><chronic inflammatory disease><cytokine><exhaust><hepatocellular carcinoma cancer model><hepatocellular carcinoma model><host response><immune system response><immune therapeutic approach><immune therapeutic interventions><immune therapeutic regimens><immune therapeutic strategy><immune therapy><immune-based cancer therapies><immune-based therapies><immune-based treatments><immuno therapy><immunogenic><immunoglobulin biosynthesis><immunoresponse><immunotherapy for cancer><immunotherapy of cancer><improved><in vivo><induction therapies><liver cancer><liver cancer model><liver cancer patient><liver carcinoma><liver malignancy><lymph organ><lymphatic organ><lymphoid organ><malignancy><malignant liver tumor><mouse model><murine model><neo-antigen><neo-epitopes><neoantigens><neoepitopes><neoplasm progression><neoplasm/cancer><neoplastic cell><neoplastic progression><new approaches><novel><novel approaches><novel strategies><novel strategy><overexpress><overexpression><oxysterol binding protein><oxysterol receptor><p50><pathway><persistent infection><plasmocyte><progenitor><progenitor cell differentiation><progenitor differentiation><programmed cell death 1><programmed cell death protein 1><programmed death 1><programs><recruit><response><sle2><social role><stem and progenitor differentiation><stem cell differentiation><systemic lupus erythematosus susceptibility 2><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment><thymus derived lymphocyte><transcription factor><tumor><tumor growth><tumor microenvironment><tumor progression><αPD-1><αPD1>
View Full Project Details on NIH Reporter
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Mehul D. Patel

DUKE UNIVERSITY, DURHAM, NC

High-opportunity lead · 74/100
Likely hiring
Above-average budget
Very recent
Active award
$506,223
FY 2026

Project Title

Regionalization of Acute Stroke Care for Rural Populations: A Systems Modeling Approach

Grant Number:

7R01MD018031-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

7/7/2023

End Date:

1/31/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary/Abstract Stroke is a leading cause of death and serious long-term disability and particularly devastating to rural communities. In the United States, rural areas have an estimated 30% greater stroke mortality compared to urban areas. Limited access to time-sensitive acute stroke ther...

Research Terms

<Accident and Emergency department><Acute><Address><Adverse effects><Apoplexy><Behavioral><Biologic Models><Biological><Biological Models><Brain Vascular Accident><Bypass><Cardiac infarction><Caring><Cause of Death><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Characteristics><Clinical><Communities><Complex><Computer Simulation><Computer based Simulation><County><Data Sources><Diagnostic Findings><Disparities><Disparity><Emergencies><Emergency Department><Emergency Situation><Emergency medical service><Emergency room><Ensure><Equilibrium><Evaluation><Future><Geographic Area><Geographic Locations><Geographic Region><Geographical Location><Geography><Guidelines><Health Care Costs><Health Care Systems><Health Costs><Hospitals><Improve Access><Individual><Influentials><Infrastructure><Integrated Health Care Systems><Intervention><Ischemic Stroke><Location><Long-term disability><Medical emergency><Mission><Model System><Modeling><Morbidity><Myocardial Infarct><Myocardial Infarction><NCMHD><NIMHD><National Center on Minority Health and Health Disparities><National Institute of Minority Health and Health Disparities><National Institute on Minority Health and Health Disparities><North Carolina><P50 Mechanism><P50 Program><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Performance><Population><Population Characteristics><Protocol><Protocols documentation><Provider><Publishing><Research><Research Resources><Resources><Route><Rural><Rural Community><Rural Population><Rural group><Rural people><Science><Sepsis><Signs and Symptoms><Source><Specialized Center><Stroke><Symptoms><System><Testing><Time><Translations><Trauma><Triage><Underserved Population><United States><access disparities><accessibility disparities><acute care><acute cerebrovascular accident><acute stroke><after stroke><balance><balance function><biologic><brain attack><cardiac infarct><care coordination><care resource use><care resource utilization><care resources><care services><care systems><cerebral vascular accident><cerebrovascular accident><comparative><compare effectiveness><computational simulation><computerized simulation><coordinating care><coronary attack><coronary infarct><coronary infarction><data collected in real world><design><designing><disparities in access><disparities in morbidity><disparities in mortality><disparity in health><emergency service><flexibility><flexible><functional outcomes><geographic site><health care resource use><health care resource utilization><health care resources><health disparity><heart attack><heart infarct><heart infarction><improved><in silico><incidence of stroke><inequality in access><inequity in access><inequity in accessibility><innovate><innovation><innovative><integrated health system><integrated system of care><model-based simulation><models and simulation><morbidity disparities><mortality><mortality disparity><novel><patient oriented outcomes><post stroke><poststroke><prospective><prototype><real world data><real world evidence><response><rural area><rural counties><rural disparities><rural health care><rural individual><rural locality><rural location><rural place><rural region><rural setting><rural under served><rural underserved><screening><screenings><simulation><standard care><standard treatment><stroke incidence><stroke outcome><stroke patient><stroke therapy><stroke treatment><stroked><strokes><translation><treating stroke><under served group><under served individual><under served people><under served population><under served rural area><underserved group><underserved individual><underserved people><underserved rural area><urban area><urban location><urban region>
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SCOTT A SMALL

COLUMBIA UNIVERSITY HEALTH SCIENCES, NEW YORK, NY

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$4,750,237
FY 2025

Project Title

Alzheimer's Disease Research Center

Grant Number:

2P30AG066462-06

Activity Code:

P30

Mechanism:

Research Centers

Agency:

NIH

Start Date:

6/15/2020

End Date:

4/30/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

OVERALL PROJECT SUMMARY In this application to renew Columbia University’s Alzheimer’s Disease Research Center (ADRC), we propose to continue our Center’s tradition that has existed at Columbia since 1989, originally as a P50 that then transitioned to a P30 in 2020. Building off our prior accomplis...

Research Terms

<AD dementia><AD pathology><AD related dementia><ADRD><Advisory Committees><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease pathology><Alzheimer's disease related dementia><Alzheimer's pathology><Alzheimers Dementia><Amentia><Articulation><Awareness><Biological><Biological Markers><Clinical><Clinical Trials><Clinical Trials Design><Collaborations><Congresses><Data><Data Management and Analysis Core><Data Management and Statistical Analysis Core><Data Management and Statistical Core><Dementia><Diagnosis><Discipline><Disease><Disorder><Disparities><Disparity><Early Diagnosis><Education Module><Educational Module><Endosomes><Environment><Ethnic Origin><Ethnicity><Fostering><Funding Opportunities><Genetic><Goals><Home><Immune response><Infrastructure><Institution><International><Intervention><Investigators><Lead><Learning Module><Link><Mission><Nerve Degeneration><Neuron Degeneration><Observation research><Observation study><Observational Study><Observational research><Pathogenicity><Pathology><Pathway interactions><Patient Recruitments><Patients><Pb element><Prevention><Primary Senile Degenerative Dementia><Proliferating><Race><Races><Receptosomes><Research><Research Infrastructure><Research Personnel><Research Resources><Research Support><Researchers><Resources><Sight><Task Forces><Tauopathies><Teaching Module><Therapeutic><Toxic effect><Toxicities><Training><Underrepresented Groups><Underrepresented Populations><Universities><Vision><advisory team><amyloid pathology><bio-markers><biologic><biologic marker><biomarker><career><clinical trial recruitment><disease prevention><disorder prevention><drug discovery><early detection><education research><heavy metal Pb><heavy metal lead><homes><host response><immune system response><immunoneurology><immunoresponse><insight><neural degeneration><neurodegeneration><neurodegenerative><neuroimmunology><neurological degeneration><neuronal degeneration><neuropathologic><neuropathologic tau><neuropathological><neuropathological tau><neuropathology><novel><outreach><participant recruitment><pathway><patient outreach><precision medicine><precision-based medicine><primary degenerative dementia><racial><racial background><racial origin><recruit><senile dementia of the Alzheimer type><social><socio-economic><socio-economically><socioeconomically><socioeconomics><tau associated neurodegeneration><tau associated neurodegenerative process><tau driven neurodegeneration><tau induced degeneration><tau induced neurodegeneration><tau mediated neurodegeneration><tau neurodegenerative disease><tau neuropathology><tau pathology><tau pathophysiology><tau proteinopathy><tau related neurodegeneration><tau-induced pathology><tauopathic neurodegenerative disorder><tauopathy><therapeutic target><trafficking><under representation of groups><under represented groups><under represented people><under represented populations><underrepresentation of groups><underrepresented people><visual function>
View Full Project Details on NIH Reporter
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David A. Brent

UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PITTSBURGH, PA

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$3,233,681
FY 2025

Project Title

The Center for Enhancing Treatment and Utilization for Depression and Emergent Suicidality (ETUDES) in Pediatric Primary Care

Grant Number:

5P50MH115838-08

Activity Code:

P50

Mechanism:

Research Centers

Agency:

NIH

Start Date:

7/17/2018

End Date:

7/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

This is a resubmission application for a Practice-based Suicide Prevention Center (PAR-20-286), and a competitive renewal of our current Alacrity P50, ETUDES, which continues to focus on the development of tools to augment the capacity of pediatric primary care (PPC) to detect, triage, and manage su...

Research Terms

<Active Follow-up><Address><Adolescent><Adolescent Youth><Anhedonia><Assess implementation><Care Givers><Caregivers><Caring><Cause of Death><Childhood><Collaborations><Consultations><Cost Analyses><Cost Analysis><Data><Depression screen><Development><Discipline><Disparities><Disparity><Effectiveness><Electronic Health Record><Ensure><Event><Exposure to><Family><Feedback><Feeling suicidal><Funding><Health Care><Health Care Systems><Health system><Heterogeneity><Implementation assessment><Individual><Intake><Intervention><Investigators><Leadership><Machine Learning><Mediator><Mental Depression><Mental Health><Mental Health Services><Mental Hygiene><Mental Hygiene Services><Mentorship><Method Acceptability><Methods><Outcome><Participant><Pathway interactions><Patients><Philadelphia><Physicians><Play><Predictive Analytics><Prevention><Prevention Research><Primary Care><Protocol><Protocols documentation><Provider><Psychological Health><QOC><Quality of Care><Randomized><Randomized, Controlled Trials><Records><Research><Research Personnel><Research Resources><Researchers><Resources><Risk Assessment><Risk Factors><Role><Safety><Sampling><Sampling Studies><Scientist><Sleep><Suicidal thoughts><Suicide><Suicide attempt><Suicide precaution><Suicide prevention><Testing><Time><Training><Triage><Victimization><Visit><Work><Youth><Youth 10-21><acceptability and feasibility><active followup><adolescent depression><adolescent suicide><adolescent suicides><adolescents with depression><annual screening><assess cost><assess effectiveness><barriers to implementation><care as usual><career><child depression><childhood depression><childhood onset depression><cohort><computer science><consultation><cost><cost assessment><cost evaluation><cyber bullying><cyberbullying><depressed adolescents><depression><depression in adolescence><depression screening><determine effectiveness><develop therapy><developmental><digital intervention><disparity in health><effectiveness assessment><effectiveness evaluation><electronic aggression><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><evaluate cost><evaluate effectiveness><evaluate implementation><evaluation of implementation><examine cost><examine effectiveness><facilitators to implementation><fatal attempt><fatal suicide><feasibility testing><follow up><follow-up><followed up><followup><health disparity><health economics><health equity promotion><high risk><implementation barriers><implementation challenges><implementation evaluation><implementation facilitators><implementation outcomes><implementation science><improved><intent to die><intervention design><intervention development><juvenile><juvenile human><machine based learning><machine learned algorithm><machine learning algorithm><machine learning based algorithm><machine learning prediction algorithm><mental health care><mobile sensing><multidisciplinary><non fatal attempt><nonfatal attempt><novel><pathway><pediatric><pediatric depression><pilot test><poor sleep><prevent suicidality><prevent suicide><promote health equity><protective factors><psychiatric co-morbidity><psychiatric comorbidity><randomisation><randomization><randomized control trial><randomly assigned><recruit><reduce suicidality><reduce suicide><reducing suicidality><reducing suicide><routine screening><screening><screenings><social media><social role><socio-economic><socio-economically><socioeconomically><socioeconomics><suicidal><suicidal adolescent><suicidal adolescents><suicidal attempt><suicidal behavior><suicidal ideation><suicidal risk><suicidal thinking><suicidal youth><suicidal youths><suicidality><suicidality prevention><suicide behavior><suicide ideation><suicide intervention><suicide rate><suicide risk><suicides><therapy design><therapy development><thoughts about suicide><tool><tool development><training opportunity><treatment as usual><treatment design><treatment development><treatment effect><usability><usual care><web site><website><youth age><youth depression>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

BERNADETTE Marie BODEN-ALBALA

UNIVERSITY OF CALIFORNIA LOS ANGELES, LOS ANGELES, CA

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$3,143,123
FY 2025

Project Title

UCLA-UCI Center for Eliminating Cardio-Metabolic Disparities in Multi-Ethnic Populations (UC END-DISPARITIES)

Grant Number:

5P50MD017366-05

Activity Code:

P50

Mechanism:

Research Centers

Agency:

NIH

Start Date:

9/24/2021

End Date:

6/30/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Project Summary/Abstract P50 UC END-DISPARITIES UC END-DISPARITIES will address the inequitable multilevel factors that promote cardiometabolic disease, including hypertension, diabetes, and complications such as atherosclerotic vascular disease and chronic kidney disease. These conditions are highl...

Research Terms

<ASCVD><Acceleration><Affect><Aging><American Indian community><Asian><Atherosclerosis><Atherosclerotic Cardiovascular Disease><Award><Behavioral><Biometrics><Biometry><Biostatistics><Black><Black race><California><Cardiometabolic Disease><Cardiometabolic Disorder><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Chronic><Chronic Disease><Chronic Illness><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Clinical Research><Clinical Sciences><Clinical Study><Cognitive Discrimination><Collaborations><Communication><Communities><County><Data Set><Decrease health disparities><Development><Diabetes Mellitus><Disadvantaged><Discrimination><Disparities><Disparity><Economics><Equity><Ethnic Group><Ethnic People><Ethnic Population><Ethnic individual><Ethnicity People><Ethnicity Population><Evaluation><Family><Funding><Future><Goals><Health><Health Policy><Health disparity mitigation><Health disparity reduction><Health equity research><Health system><Heart Vascular><Hypertension><Individual><Individuals from minority><Individuals of minority><Inequity><Infrastructure><Institution><Intervention><Investigators><Latino><Link><Los Angeles><Low income><Lower health disparities><Measurement><Measures><Mentors><Mentorship><Methodology><Minority><Minority Groups><Minority Health Research><Minority People><Minority Population><Minority individual><Minority research><Minority-Serving Institution><Mitigate health disparities><Morbidity><Morbidity - disease rate><NCMHD><NIGMS><NIH><NIMHD><National Center on Minority Health and Health Disparities><National Institute of General Medical Sciences><National Institute of Minority Health and Health Disparities><National Institute on Minority Health and Health Disparities><National Institutes of Health><Oranges><Outcome><Outcomes Research><Pacific Island individual><Pacific Island population><Pacific Islander><Participant><PhenX Toolkit><Phenotypes and eXposures Toolkit><Phenx><Pilot Projects><Population><Postdoc><Postdoctoral Fellow><Public Health><R-Series Research Projects><R01 Mechanism><R01 Program><Reduce health disparities><Research><Research Associate><Research Grants><Research Infrastructure><Research Institute><Research Methodology><Research Methods><Research Personnel><Research Project Grants><Research Projects><Research Resources><Research in health equity><Researchers><Resource Sharing><Resources><Risk><Risk Factors><Stress><Training><Training Programs><Translational Research><Translational Science><United States National Institutes of Health><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Work><allostatic load><atheromatosis><atherosclerotic disease><atherosclerotic vascular disease><cardiometabolic><cardiometabolic risk><cardiometabolism><care outcomes><career><catalyst><chronic disorder><chronic kidney disease><circulatory system><community academic collaboration><community academic partnership><community academic research partnership><community engaged participatory research><community engaged research><community engagement><community partnered research><community university partnership><community-engaged study><community-partnered study><data harmonization><data sharing><design><designing><developmental><diabetes><disease disparity><disease prevention><disorder prevention><disparity in health><economic><engagement with communities><ethnic subgroup><ethnicity group><flexibility><flexible><harmonized data><health IT><health care outcomes><health care policy><health disparity><health equity><health equity-focused research><health information technology><high blood pressure><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><implementation science><improved><inflammation marker><inflammatory marker><innovate><innovation><innovative><intervention design><marginalized group><marginalized individual><marginalized people><marginalized population><meeting><meetings><minority communities><minority institution><mortality><multi-ethnic><multiethnic><patient population><pilot study><post-doc><post-doctoral><post-doctoral trainee><premature><prematurity><prevent><preventing><programs><research and methods><research associates><research in minorities><research on health equity><research on minorities><research related to health equity><research related to minorities><research to attain health equity><research with minorities><social><social genomics><social health determinants><socio-genomics><sociogenomics><structural determinants><structural factors><synergism><therapy design><tool><translation research><translational investigation><treatment design><vulnerable community>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

ARLEEN F. BROWN

UNIVERSITY OF CALIFORNIA LOS ANGELES, LOS ANGELES, CA

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$3,143,123
FY 2025

Project Title

UCLA-UCI Center for Eliminating Cardio-Metabolic Disparities in Multi-Ethnic Populations (UC END-DISPARITIES)

Grant Number:

5P50MD017366-05

Activity Code:

P50

Mechanism:

Research Centers

Agency:

NIH

Start Date:

9/24/2021

End Date:

6/30/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Project Summary/Abstract P50 UC END-DISPARITIES UC END-DISPARITIES will address the inequitable multilevel factors that promote cardiometabolic disease, including hypertension, diabetes, and complications such as atherosclerotic vascular disease and chronic kidney disease. These conditions are highl...

Research Terms

<ASCVD><Acceleration><Affect><Aging><American Indian community><Asian><Atherosclerosis><Atherosclerotic Cardiovascular Disease><Award><Behavioral><Biometrics><Biometry><Biostatistics><Black><Black race><California><Cardiometabolic Disease><Cardiometabolic Disorder><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Chronic><Chronic Disease><Chronic Illness><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Clinical Research><Clinical Sciences><Clinical Study><Cognitive Discrimination><Collaborations><Communication><Communities><County><Data Set><Decrease health disparities><Development><Diabetes Mellitus><Disadvantaged><Discrimination><Disparities><Disparity><Economics><Equity><Ethnic Group><Ethnic People><Ethnic Population><Ethnic individual><Ethnicity People><Ethnicity Population><Evaluation><Family><Funding><Future><Goals><Health><Health Policy><Health disparity mitigation><Health disparity reduction><Health equity research><Health system><Heart Vascular><Hypertension><Individual><Individuals from minority><Individuals of minority><Inequity><Infrastructure><Institution><Intervention><Investigators><Latino><Link><Los Angeles><Low income><Lower health disparities><Measurement><Measures><Mentors><Mentorship><Methodology><Minority><Minority Groups><Minority Health Research><Minority People><Minority Population><Minority individual><Minority research><Minority-Serving Institution><Mitigate health disparities><Morbidity><Morbidity - disease rate><NCMHD><NIGMS><NIH><NIMHD><National Center on Minority Health and Health Disparities><National Institute of General Medical Sciences><National Institute of Minority Health and Health Disparities><National Institute on Minority Health and Health Disparities><National Institutes of Health><Oranges><Outcome><Outcomes Research><Pacific Island individual><Pacific Island population><Pacific Islander><Participant><PhenX Toolkit><Phenotypes and eXposures Toolkit><Phenx><Pilot Projects><Population><Postdoc><Postdoctoral Fellow><Public Health><R-Series Research Projects><R01 Mechanism><R01 Program><Reduce health disparities><Research><Research Associate><Research Grants><Research Infrastructure><Research Institute><Research Methodology><Research Methods><Research Personnel><Research Project Grants><Research Projects><Research Resources><Research in health equity><Researchers><Resource Sharing><Resources><Risk><Risk Factors><Stress><Training><Training Programs><Translational Research><Translational Science><United States National Institutes of Health><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Work><allostatic load><atheromatosis><atherosclerotic disease><atherosclerotic vascular disease><cardiometabolic><cardiometabolic risk><cardiometabolism><care outcomes><career><catalyst><chronic disorder><chronic kidney disease><circulatory system><community academic collaboration><community academic partnership><community academic research partnership><community engaged participatory research><community engaged research><community engagement><community partnered research><community university partnership><community-engaged study><community-partnered study><data harmonization><data sharing><design><designing><developmental><diabetes><disease disparity><disease prevention><disorder prevention><disparity in health><economic><engagement with communities><ethnic subgroup><ethnicity group><flexibility><flexible><harmonized data><health IT><health care outcomes><health care policy><health disparity><health equity><health equity-focused research><health information technology><high blood pressure><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><implementation science><improved><inflammation marker><inflammatory marker><innovate><innovation><innovative><intervention design><marginalized group><marginalized individual><marginalized people><marginalized population><meeting><meetings><minority communities><minority institution><mortality><multi-ethnic><multiethnic><patient population><pilot study><post-doc><post-doctoral><post-doctoral trainee><premature><prematurity><prevent><preventing><programs><research and methods><research associates><research in minorities><research on health equity><research on minorities><research related to health equity><research related to minorities><research to attain health equity><research with minorities><social><social genomics><social health determinants><socio-genomics><sociogenomics><structural determinants><structural factors><synergism><therapy design><tool><translation research><translational investigation><treatment design><vulnerable community>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Keith C Norris

UNIVERSITY OF CALIFORNIA LOS ANGELES, LOS ANGELES, CA

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$3,143,123
FY 2025

Project Title

UCLA-UCI Center for Eliminating Cardio-Metabolic Disparities in Multi-Ethnic Populations (UC END-DISPARITIES)

Grant Number:

5P50MD017366-05

Activity Code:

P50

Mechanism:

Research Centers

Agency:

NIH

Start Date:

9/24/2021

End Date:

6/30/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Project Summary/Abstract P50 UC END-DISPARITIES UC END-DISPARITIES will address the inequitable multilevel factors that promote cardiometabolic disease, including hypertension, diabetes, and complications such as atherosclerotic vascular disease and chronic kidney disease. These conditions are highl...

Research Terms

<ASCVD><Acceleration><Affect><Aging><American Indian community><Asian><Atherosclerosis><Atherosclerotic Cardiovascular Disease><Award><Behavioral><Biometrics><Biometry><Biostatistics><Black><Black race><California><Cardiometabolic Disease><Cardiometabolic Disorder><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Chronic><Chronic Disease><Chronic Illness><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Clinical Research><Clinical Sciences><Clinical Study><Cognitive Discrimination><Collaborations><Communication><Communities><County><Data Set><Decrease health disparities><Development><Diabetes Mellitus><Disadvantaged><Discrimination><Disparities><Disparity><Economics><Equity><Ethnic Group><Ethnic People><Ethnic Population><Ethnic individual><Ethnicity People><Ethnicity Population><Evaluation><Family><Funding><Future><Goals><Health><Health Policy><Health disparity mitigation><Health disparity reduction><Health equity research><Health system><Heart Vascular><Hypertension><Individual><Individuals from minority><Individuals of minority><Inequity><Infrastructure><Institution><Intervention><Investigators><Latino><Link><Los Angeles><Low income><Lower health disparities><Measurement><Measures><Mentors><Mentorship><Methodology><Minority><Minority Groups><Minority Health Research><Minority People><Minority Population><Minority individual><Minority research><Minority-Serving Institution><Mitigate health disparities><Morbidity><Morbidity - disease rate><NCMHD><NIGMS><NIH><NIMHD><National Center on Minority Health and Health Disparities><National Institute of General Medical Sciences><National Institute of Minority Health and Health Disparities><National Institute on Minority Health and Health Disparities><National Institutes of Health><Oranges><Outcome><Outcomes Research><Pacific Island individual><Pacific Island population><Pacific Islander><Participant><PhenX Toolkit><Phenotypes and eXposures Toolkit><Phenx><Pilot Projects><Population><Postdoc><Postdoctoral Fellow><Public Health><R-Series Research Projects><R01 Mechanism><R01 Program><Reduce health disparities><Research><Research Associate><Research Grants><Research Infrastructure><Research Institute><Research Methodology><Research Methods><Research Personnel><Research Project Grants><Research Projects><Research Resources><Research in health equity><Researchers><Resource Sharing><Resources><Risk><Risk Factors><Stress><Training><Training Programs><Translational Research><Translational Science><United States National Institutes of Health><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Work><allostatic load><atheromatosis><atherosclerotic disease><atherosclerotic vascular disease><cardiometabolic><cardiometabolic risk><cardiometabolism><care outcomes><career><catalyst><chronic disorder><chronic kidney disease><circulatory system><community academic collaboration><community academic partnership><community academic research partnership><community engaged participatory research><community engaged research><community engagement><community partnered research><community university partnership><community-engaged study><community-partnered study><data harmonization><data sharing><design><designing><developmental><diabetes><disease disparity><disease prevention><disorder prevention><disparity in health><economic><engagement with communities><ethnic subgroup><ethnicity group><flexibility><flexible><harmonized data><health IT><health care outcomes><health care policy><health disparity><health equity><health equity-focused research><health information technology><high blood pressure><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><implementation science><improved><inflammation marker><inflammatory marker><innovate><innovation><innovative><intervention design><marginalized group><marginalized individual><marginalized people><marginalized population><meeting><meetings><minority communities><minority institution><mortality><multi-ethnic><multiethnic><patient population><pilot study><post-doc><post-doctoral><post-doctoral trainee><premature><prematurity><prevent><preventing><programs><research and methods><research associates><research in minorities><research on health equity><research on minorities><research related to health equity><research related to minorities><research to attain health equity><research with minorities><social><social genomics><social health determinants><socio-genomics><sociogenomics><structural determinants><structural factors><synergism><therapy design><tool><translation research><translational investigation><treatment design><vulnerable community>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Suresh S. Ramalingam

EMORY UNIVERSITY, ATLANTA, GA

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$3,106,678
FY 2025

Project Title

Winship Cancer Institute Cancer Center Support Grant

Grant Number:

5P30CA138292-16

Activity Code:

P30

Mechanism:

Research Centers

Agency:

NIH

Start Date:

4/7/2009

End Date:

3/31/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY/ABSTRACT OVERALL The mission of Winship Cancer Institute of Emory University (Winship) is to discover cures for cancer and inspire hope. Winship is the only NCI-designated comprehensive cancer center in Georgia, the eighth most populous state in the United States, with the second hig...

Research Terms

<AIDS Virus><Acceleration><Acquired Immune Deficiency Syndrome Virus><Acquired Immunodeficiency Syndrome Virus><Address><Area><Award><Basic Research><Basic Science><Black Populations><Black group><Black individual><Black people><Blacks><CCSG><Cancer Burden><Cancer Center Support Grant><Cancer health equity><Cancers><Catchment Area><Clinical><Clinical Sciences><Clinical Trials><Communication><Community Outreach><Comprehensive Cancer Center><Country><Diagnosis><Disease><Disorder><ET-CTN><Early Therapeutic-Clinical Trials Network><Education><Education and Outreach><Education and Training><Educational aspects><Fostering><Funding><Generalized Growth><Growth><HIV><HPV Vaccination><Health><Health Policy><Health Promotion><Hispanic Populations><Hispanic group><Hispanic individual><Hispanic people><Hispanics><Human Immunodeficiency Viruses><Human Papilloma Virus Vaccination><Human Papillomavirus Vaccination><Individual><Infrastructure><Institution><Instruction and Outreach><Intervention><Investigators><Investments><LAV-HTLV-III><Leadership><Legislation><Lymphadenopathy-Associated Virus><Malignant Neoplasms><Malignant Tumor><Malignant Tumor of the Lung><Malignant neoplasm of lung><Manuscripts><Mentorship><Mission><Multiple Myeloma><National Cancer Burden><P50 Mechanism><P50 Program><Patients><Peer Review><Phase><Plasma-Cell Myeloma><Population Sciences><Publishing><Pulmonary Cancer><Pulmonary malignant Neoplasm><QOL><Quality of life><Reporting><Research><Research Personnel><Research Resources><Researchers><Resource Sharing><Resources><Risk><Rural><Salutogenesis><Schools><Science><Screening for cancer><Societies><Specialized Center><Statutes and Laws><Strategic Planning><Time><Tissue Growth><Training><Training and Education><Training and Outreach><Translational Research><Translational Science><Translations><Tutoring and Outreach><Underrepresented Groups><Underrepresented Populations><Underserved Population><United States><Universities><Virus-HIV><anti-cancer research><cancer care><cancer disparity><cancer health disparity><cancer immunology><cancer research><cancer-related health disparity><clinical care><community based organizations><community engagement><community organizations><community partners><community partnership><community-based partners><disparity in cancer><diversity, equity, and inclusiveness><early cancer detection><engagement with communities><equity, diversity, and inclusion><experience><first in man><first-in-human><health care policy><health literacy><improved><innovate><innovation><innovative><leukemia/lymphoma><lung cancer><lymphoma/leukemia><malignancy><member><myeloma><myelomatosis><neoplasm immunology><neoplasm/cancer><new anti-cancer agent><new anticancer agent><new anticancer drug><new antineoplastic><new cancer drug><novel anti-cancer agent><novel anti-cancer drug><novel anticancer agent><novel anticancer drug><novel antineoplastic><novel cancer drug><ontogeny><phase 1 trial><phase I trial><programs><promoting health><screening cancer patients><tobacco control><translation><translation research><translational investigation><treatment trial><tumor immunology><under representation of groups><under represented groups><under represented people><under represented populations><under served group><under served individual><under served people><under served population><underrepresentation of groups><underrepresented people><underserved group><underserved individual><underserved people>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

A DAVID REDISH

UNIVERSITY OF MINNESOTA, MINNEAPOLIS, MN

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$3,095,644
FY 2025

Project Title

Dysfunctional State Representations in Psychosis: From Neurophysiology to Neuroplasticity-based Treatment

Grant Number:

2P50MH119569-06

Activity Code:

P50

Mechanism:

Research Centers

Agency:

NIH

Start Date:

4/1/2020

End Date:

4/30/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

OVERALL - PROJECT SUMMARY The purpose of our P50 Conte Center is to develop, test, and apply computational models of disrupted state representation processes to behavioral and neural measures relevant to psychosis spectrum illness across mouse, macaque, and human experiments. Our premise is that, in...

Research Terms

<Ablation><Address><Affect><Animal Experiments><Animals><Ants><Behavior><Behavioral><Biological Markers><Brain><Brain Nervous System><CNS plasticity><Clinical Sciences><Cognition><Cognitive><Computational Science><Computer Models><Computerized Models><Computing Methodologies><Corpus Striatum><Corpus striatum structure><Decision Making><Dimensions><Dopamine><EEG><Educational process of instructing><Electroencephalogram><Electroencephalography><Encephalon><Ensure><Environment><Feedback><Funding><Goals><Heterogeneity><Human><Hydroxytyramine><Impairment><Individual><Knowledge><Learning><Macaca><Macaque><Maintenance><Maps><Measures><Methods><Mice><Mice Mammals><Modeling><Modern Man><Motivation><Murine><Mus><Neurocognition><Neurocognitive><Neuronal Plasticity><Pathogenicity Factors><Patients><Pattern><Precision therapeutics><Process><Psychoses><Research><Rewards><Role><Science><Striate Body><Striatum><Structure><Symptoms><System><Task Performances><Teaching><Testing><Theoretic Models><Theoretical model><Time><Translations><Update><Virulence Factors><animal experiment><antagonism><antagonist><bio-markers><biologic marker><biomarker><biotypes><central nervous system plasticity><cognitive control><computational methodology><computational methods><computational modeling><computational models><computational neuroscience><computer based method><computer based models><computer methods><computerized modeling><computing method><early psychosis><experiment><experimental animal><experimental animals><experimental research><experimental study><experiments><fMRI/EEG><functional magnetic resonance imaging/electroencephalography><functional outcomes><improved><innovate><innovation><innovative><insight><inter-individual variability><inter-individual variation><neural><neural plasticity><neurophysiological><neurophysiology><neuroplastic><neuroplasticity><operation><operations><pharmacologic><precision therapies><precision treatment><response><reward processing><sensory system><social role><striatal><success><symptom cluster><translation>
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Sophia Vinogradov

UNIVERSITY OF MINNESOTA, MINNEAPOLIS, MN

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$3,095,644
FY 2025

Project Title

Dysfunctional State Representations in Psychosis: From Neurophysiology to Neuroplasticity-based Treatment

Grant Number:

2P50MH119569-06

Activity Code:

P50

Mechanism:

Research Centers

Agency:

NIH

Start Date:

4/1/2020

End Date:

4/30/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

OVERALL - PROJECT SUMMARY The purpose of our P50 Conte Center is to develop, test, and apply computational models of disrupted state representation processes to behavioral and neural measures relevant to psychosis spectrum illness across mouse, macaque, and human experiments. Our premise is that, in...

Research Terms

<Ablation><Address><Affect><Animal Experiments><Animals><Ants><Behavior><Behavioral><Biological Markers><Brain><Brain Nervous System><CNS plasticity><Clinical Sciences><Cognition><Cognitive><Computational Science><Computer Models><Computerized Models><Computing Methodologies><Corpus Striatum><Corpus striatum structure><Decision Making><Dimensions><Dopamine><EEG><Educational process of instructing><Electroencephalogram><Electroencephalography><Encephalon><Ensure><Environment><Feedback><Funding><Goals><Heterogeneity><Human><Hydroxytyramine><Impairment><Individual><Knowledge><Learning><Macaca><Macaque><Maintenance><Maps><Measures><Methods><Mice><Mice Mammals><Modeling><Modern Man><Motivation><Murine><Mus><Neurocognition><Neurocognitive><Neuronal Plasticity><Pathogenicity Factors><Patients><Pattern><Precision therapeutics><Process><Psychoses><Research><Rewards><Role><Science><Striate Body><Striatum><Structure><Symptoms><System><Task Performances><Teaching><Testing><Theoretic Models><Theoretical model><Time><Translations><Update><Virulence Factors><animal experiment><antagonism><antagonist><bio-markers><biologic marker><biomarker><biotypes><central nervous system plasticity><cognitive control><computational methodology><computational methods><computational modeling><computational models><computational neuroscience><computer based method><computer based models><computer methods><computerized modeling><computing method><early psychosis><experiment><experimental animal><experimental animals><experimental research><experimental study><experiments><fMRI/EEG><functional magnetic resonance imaging/electroencephalography><functional outcomes><improved><innovate><innovation><innovative><insight><inter-individual variability><inter-individual variation><neural><neural plasticity><neurophysiological><neurophysiology><neuroplastic><neuroplasticity><operation><operations><pharmacologic><precision therapies><precision treatment><response><reward processing><sensory system><social role><striatal><success><symptom cluster><translation>
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Mary Allison Barlow

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$2,828,475
FY 2025

Project Title

Center for Innovative Research, Capacity Building and Leadership Development to End Substance Use Harms (CIRCLE)

Grant Number:

5P50DA058619-03

Activity Code:

P50

Mechanism:

Research Centers

Agency:

NIH

Start Date:

9/1/2023

End Date:

6/30/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Center for Innovative Research, Capacity Building and Leadership Development to End Substance Use Harms (CIRCLE) Drug and alcohol use related health problems and overdose deaths disproportionately impact quality and longevity of life for many American Indian and Alaska Native (AI/AN) communities. Th...

Research Terms

<Address><Alaska Indian><Alaska Native><Alaskan American><Alaskan Indian><Alaskan Native><Alaskan Native American><Alcohol Drinking><Alcohol consumption><American Indian><American Indian community><Area><Cessation of life><Collaborations><Communities><Death><Development><Drug usage><Education><Educational aspects><EtOH drinking><EtOH use><Fostering><Goals><Health><Intervention><Investigators><Leadership><Length of Life><Life><Longevity><Measures><Methodology><Methods><Outcome><Pilot Projects><Policies><Policy Maker><Prevention><Public Health><R-Series Research Projects><R01 Mechanism><R01 Program><Recovery><Research><Research Grants><Research Personnel><Research Project Grants><Research Projects><Research Resources><Research Support><Researchers><Resources><Risk Factors><Science><Services><Source><Structure><System><Training><Training Activity><Translating><Tribal Participatory Research><Tribally Based Participatory Research><Tribally-driven participatory research><Tribes><alcohol ingestion><alcohol intake><alcohol product use><alcohol use><alcoholic beverage consumption><alcoholic drink intake><community based participatory research><community led research><community participatory research><community partnered participatory research><developmental><drug abuse prevention><drug addiction prevention><drug use><drug use prevention><ethanol consumption><ethanol drinking><ethanol ingestion><ethanol intake><ethanol product use><ethanol use><innovate><innovation><innovative><intervention effect><leadership development><multidisciplinary><novel><outreach><overdose death><overdose fatalities><participatory action research><pilot study><prevent drug abuse><prevent drug addiction><prevent drug use><programs><protective factors><substance use><substance using><training module><tribally engaged research><tribally led research><tribally-driven research><uptake><urban American Indian><urban Indian><urban Native American>
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Melissa L. Walls

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$2,828,475
FY 2025

Project Title

Center for Innovative Research, Capacity Building and Leadership Development to End Substance Use Harms (CIRCLE)

Grant Number:

5P50DA058619-03

Activity Code:

P50

Mechanism:

Research Centers

Agency:

NIH

Start Date:

9/1/2023

End Date:

6/30/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Center for Innovative Research, Capacity Building and Leadership Development to End Substance Use Harms (CIRCLE) Drug and alcohol use related health problems and overdose deaths disproportionately impact quality and longevity of life for many American Indian and Alaska Native (AI/AN) communities. Th...

Research Terms

<Address><Alaska Indian><Alaska Native><Alaskan American><Alaskan Indian><Alaskan Native><Alaskan Native American><Alcohol Drinking><Alcohol consumption><American Indian><American Indian community><Area><Cessation of life><Collaborations><Communities><Death><Development><Drug usage><Education><Educational aspects><EtOH drinking><EtOH use><Fostering><Goals><Health><Intervention><Investigators><Leadership><Length of Life><Life><Longevity><Measures><Methodology><Methods><Outcome><Pilot Projects><Policies><Policy Maker><Prevention><Public Health><R-Series Research Projects><R01 Mechanism><R01 Program><Recovery><Research><Research Grants><Research Personnel><Research Project Grants><Research Projects><Research Resources><Research Support><Researchers><Resources><Risk Factors><Science><Services><Source><Structure><System><Training><Training Activity><Translating><Tribal Participatory Research><Tribally Based Participatory Research><Tribally-driven participatory research><Tribes><alcohol ingestion><alcohol intake><alcohol product use><alcohol use><alcoholic beverage consumption><alcoholic drink intake><community based participatory research><community led research><community participatory research><community partnered participatory research><developmental><drug abuse prevention><drug addiction prevention><drug use><drug use prevention><ethanol consumption><ethanol drinking><ethanol ingestion><ethanol intake><ethanol product use><ethanol use><innovate><innovation><innovative><intervention effect><leadership development><multidisciplinary><novel><outreach><overdose death><overdose fatalities><participatory action research><pilot study><prevent drug abuse><prevent drug addiction><prevent drug use><programs><protective factors><substance use><substance using><training module><tribally engaged research><tribally led research><tribally-driven research><uptake><urban American Indian><urban Indian><urban Native American>
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KENT E. HUTCHISON

UNIVERSITY OF COLORADO DENVER, Aurora, CO

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$2,803,466
FY 2025

Project Title

Rocky Mountain Cannabis Research Center

Grant Number:

5P50DA056408-03

Activity Code:

P50

Mechanism:

Research Centers

Agency:

NIH

Start Date:

9/1/2023

End Date:

6/30/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY/ABSTRACT ROCKY MOUNTAIN CANNABIS RESEARCH CENTER (RM-CRC) The United States has recently experienced enormous changes in the legal status and public acceptance of cannabis. Recreational and medical cannabis products that contain varying amounts of tetrahydrocannabinol (THC) and canna...

Research Terms

<12-20 years old><21+ years old><9-ene-Tetrahydrocannabinol><Acute><Adolescence><Adult><Adult Human><Affect><Assay><Behavior><Behavioral><Bioassay><Biological><Biological Assay><Biological Markers><Blood><Blood Reticuloendothelial System><Blood Sample><Blood specimen><COBRE><Cannabidiol><Cannabinoids><Cannabis><Center of Biomedical Research Excellence><Centers of Research Excellence><Communities><D.C. Washington><D9-tetrahydrocannabinol><DC Washington><Data><Data Collection><Data Set><Delta-9-Tetrahydrocannabinol><District of Columbia><Dose><Endocannabinoids><Endogenous Cannabinoids><Epidiolex><Foundations><Funding><Future><Goals><Health><Hemp><Industry><Knowledge><Laboratories><Legal><Legal Status><Lipids><Machine Learning><Measures><Mediating><Medical Marijuana><Medicinal Marijuana><Modeling><Moods><NIH><National Institutes of Health><Neurocognition><Neurocognitive><North America><Outcome><Participant><Pharmaceutical Agent><Pharmaceuticals><Pharmacies><Pharmacologic Substance><Pharmacological Substance><Pharmacology><Pharmacy facility><Pilot Projects><Placebos><Public Health><R-Series Research Projects><R01 Mechanism><R01 Program><Randomized><Recreation><Research><Research Grants><Research Project Grants><Research Projects><Research Resources><Resources><Risk><Sampling><Scientist><Self Administered><Self Administration><Sham Treatment><Structure><System><Terpene Compound><Terpenes><Terpenoids><Tetrahydrocannabinol><Time><United States><United States National Institutes of Health><adolescence (12-20)><adulthood><age group><behavior measurement><behavior outcome><behavioral measure><behavioral measurement><behavioral outcome><bio-markers><biologic><biologic marker><biomarker><data analysis core><data analysis research core><data analytics core><data analytics research core><data cleaning><data cleansing><data harmonization><data sharing><delta(1)-THC><delta(1)-Tetrahydrocannabinol><delta(9)-THC><delta(9)-Tetrahydrocannabinol><depository><design><designing><eCB system><early adulthood><emerging adult><endocannabinoid system><endogenous cannabinoid system><experience><harmonized data><innovate><innovation><innovative><life span><lifespan><lipid mediator><machine based learning><medical cannabis><medicinal cannabis><mid life><mid-life><middle age><middle aged><midlife><novel><older adult><older adulthood><pharmaceutical><pilot study><randomisation><randomization><randomly assigned><repository><response><sham therapy><success><therapeutic cannabis><therapeutic marijuana><user-friendly><web based interface><Δ(1)-THC><Δ(1)-tetrahydrocannabinol><Δ(9)-THC><Δ(9)-tetrahydrocannabinol><Δ-9-tetrahydrocannabinol><Δ9-tetrahydrocannabinol>
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Bruce Jay Gantz

UNIVERSITY OF IOWA, IOWA CITY, IA

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$2,754,802
FY 2025

Project Title

Iowa Cochlear Implant Clinical Research Center VIII

Grant Number:

5P50DC000242-38

Activity Code:

P50

Mechanism:

Research Centers

Agency:

NIH

Start Date:

9/15/1985

End Date:

4/30/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Program Director/Principal Investigator (Last, First, Middle): Gantz, Bruce J. PROJECT SUMMARY - OVERVIEW Cochlear implants (CI) have become the standard of care for managing profound sensorineural hearing loss. These devices provide significant improvement in word understanding in quiet but have li...

Research Terms

<Accent><Acoustic Nerve><Acoustics><Age><Attention><Auditory><Auditory system><Bilateral><Binaural><Bionomics><Brain><Brain Nervous System><Cell Communication and Signaling><Cell Signaling><Characteristics><Clinical Research><Clinical Study><Cochlear Implants><Cochlear Nerve><Cochlear Prosthesis><Cochlear Root of Acoustic Nerve><Cochlear Root of Eighth Cranial Nerve><Cognition><Cognitive><Communication><Communication challenge><Communication difficulty><Compensation><Cranial Nerve Eight><Cranial Nerve VIII><Cues><Data><Devices><Ear><Ecology><Eighth Cranial Nerve><Electrodes><Encephalon><Environment><Frequencies><Funding><Genetic Diversity><Genetic Variation><Grant><Grouping><Hearing><Hearing Aids><Hearing Loss><Human><Hypoacuses><Hypoacusis><Immediate Memory><Individual><Intracellular Communication and Signaling><Investigation><Iowa><Life><Managed Care><Medical><Medical Rehabilitation><Modality><Modern Man><Noise><Outcome><Patients><Perception><Performance><Peripheral><Persons><Population><Predictive Factor><Principal Investigator><Process><QOL><Quality of life><R-Series Research Projects><R01 Mechanism><R01 Program><Registries><Rehabilitation><Rehabilitation therapy><Research><Research Grants><Research Project Grants><Research Projects><Residual><Residual state><Robotics><Sensorineural Deafness><Sensorineural Hearing Loss><Sensory Hearing Loss><Short-Term Memory><Side><Signal Transduction><Signal Transduction Systems><Signaling><Social Interaction><Socialization><Speech><Speech Perception><Steroid Compound><Steroids><Structure><Transcend><Uncertainty><VIIIth Cranial Nerve><Vestibulocochlear Nerve><Work><ages><assistive hearing device><assistive listening device><auditory nerve><biological signal transduction><cognitive capacity><cognitive function><cognitive process><cognitive system><cohort><computer based prediction><deafness><demographics><doubt><dysfunctional hearing><executive control><executive function><face mask><flexibility><flexible><groupings><hearing amplification><hearing assistance><hearing assistive device><hearing challenged><hearing defect><hearing deficient><hearing deficit><hearing device><hearing difficulty><hearing dysfunction><hearing impairment><hearing in noise><implantation><improved><information processing><insight><language processing><lexical processing><outcome prediction><patient registry><predictive modeling><preservation><programs><psychosocial well-being><psychosocial wellbeing><psychosocial wellness><rehab therapy><rehabilitative><rehabilitative therapy><sensorineural hearing impairment><speech in background noise><speech in noise><speech in speech recognition><speech recognition in noise><standard of care><success><working memory>
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Mark P McGovern

STANFORD UNIVERSITY, STANFORD, CA

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$2,734,809
FY 2025

Project Title

Center for Dissemination and Implementation At Stanford (C-DIAS)

Grant Number:

5P50DA054072-04

Activity Code:

P50

Mechanism:

Research Centers

Agency:

NIH

Start Date:

8/1/2022

End Date:

5/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

C-DIAS OVERALL: PROJECT SUMMARY/ABSTRACT This is a revised proposal for a NIDA P50 Center of Excellence: The Center for Dissemination and Implementation At Stanford (C-DIAS). Our overarching goal is simple to say, yet paradigm shifting if achieved: Equitable access to evidence-based addiction treatm...

Research Terms

<Acceleration><Address><Adoption><Area><Assess implementation><Communities><Consultations><County><Creativeness><Dedications><Disparity population><Dissemination and Implementation><Economic Models><Education and Training><Epidemic><Equity><Evidence based treatment><Fellowship><Fostering><Funding><Geography><Goals><Health Care Systems><Health Policy><Health Services><Health Services Evaluation><Health Services Research><Health system><Implementation assessment><Individual><Intervention><Lead><Leadership><Link><Measures><Medical Care Research><Medicine><Mentorship><Methods><Modeling><NIDA><NIMH><National Institute of Drug Abuse><National Institute of Mental Health><National Institute on Drug Abuse><Outcome><Overdose reduction><Patients><Pb element><Phase><Policy Maker><Preparation><Privatization><Public Health><R-Series Research Projects><R01 Mechanism><R01 Program><Reaction><Research><Research Grants><Research Institute><Research Project Grants><Research Projects><Research Resources><Resources><Services><Standardization><Strategic Planning><Substance Use Disorder><System><Techniques><Training and Education><Translating><Translations><Variant><Variation><addiction><addictive disorder><consultation><contingency management><cost><creativity><data harmonization><design><designing><digital access><digital accessibility><digital equality><digital equity><digital inclusion><digital therapeutics><digital therapy><digital treatment><disadvantaged group><disadvantaged individual><disadvantaged people><disadvantaged population><disadvantaged subgroup><disparities across groups><disparity across subgroups><disparity among groups><disparity among subgroups><disparity between groups><disparity between subgroups><disparity in care><disparity in health care><dissemination science><evaluate implementation><evaluation of implementation><evidence base><group disparity><group inequality><group inequity><harmonized data><health care disparity><health care inequality><health care inequity><health care policy><health economics><heavy metal Pb><heavy metal lead><human capital><implementation efforts><implementation evaluation><implementation research><implementation science><implementation strategy><improved><inequalities among populations><inequalities between populations><inequalities in populations><inequality across populations><inequality among groups><inequality between groups><inequality in groups><inequities among populations><inequities between populations><inequities in populations><inequity across groups><inequity across populations><inequity between groups><inequity in groups><internet resource><member><multidisciplinary><on-line compendium><on-line resource><online compendium><online resource><opiate use disorder><opioid use disorder><overdose death><overdose fatalities><pharmacologic><population inequality><population inequity><preparations><primary care clinic><psychosocial><psychostimulant use><reduce overdose><reduction in overdose><scale up><service delivery><services research><standardize measure><stimulant use><strategies for implementation><subgroup disparity><substance use and disorder><success><synergism><tool><translation><treatment program><treatment services><unequal group><unequal population><use of stimulants><web resource><web-based resource>
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Sharon G Kujawa

MASSACHUSETTS EYE AND EAR INFIRMARY, BOSTON, MA

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$2,684,343
FY 2025

Project Title

Cochlear Synaptopathy: Prevalence, Diagnosis and Functional Consequences

Grant Number:

5P50DC015857-09

Activity Code:

P50

Mechanism:

Research Centers

Agency:

NIH

Start Date:

8/2/2017

End Date:

7/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Overall Project Summary Insights from animal studies of noise-induced and age-related hearing loss suggest that the most vulnerable elements in the inner ear are the synaptic connections between hair cells and sensory neurons. This primary cochlear neural degeneration (CND) does not elevate thresho...

Research Terms

<Acceleration><Acoustic Nerve><Acoustics><Afferent Neurons><Aging><Aminoglycosides><Animal Model><Animal Models and Related Studies><Animals><Assay><Audiogram><Audiology><Audiometric Test><Audiometry><Auditory><Autopsy><Behavioral><Behavioral Assay><Bilateral><Bioassay><Biological Assay><Biological Markers><Brain><Brain Nervous System><CDDP><Causality><Cell Body><Cells><Cellular injury><Cis-diammine-dichloroplatinum><Cis-diamminedichloridoplatinum><Cis-diamminedichloro Platinum (II)><Cis-dichloroammine Platinum (II)><Cis-platinous Diamine Dichloride><Cis-platinum II><Cis-platinum II Diamine Dichloride><Cisplatin><Cisplatina><Cisplatinum><Clinical><Clinical Trials><Clinical Trials Design><Cochlea><Cochlear Organ><Corti Cell><Cranial Nerve Eight><Cranial Nerve VIII><Cysplatyna><Data Bases><Databases><Denervation><Diagnosis><Diagnostic><Diagnostic tests><Dichlorodiammineplatinum><Disease><Disinhibition><Disorder><Drug Exposure><Drugs><Ear><Eighth Cranial Nerve><Electrophysiology><Electrophysiology (science)><Elements><Encephalon><Environment><Etiology><Exposure to><Frequencies><Generations><Hair Cells><Hearing><Hearing Disorders><Hearing Loss><Hearing Tests><Hearing problem><History><Human><Hyperactivity><Hyperacusia><Hyperacusis><Hypoacuses><Hypoacusis><Individual><Infirmity><Injury><Inner Hair Cells><Inner ear hair cells><Internal Ear><Laboratories><Labyrinth><Life Style><Lifestyle><Loudness Perception><Loudness Perception Disturbances><Loudness Recruitment><Maps><Measurement><Measures><Mediation><Medication><Meniere's Disease><Meniere's Disorder><Meniere's Syndrome><Mice><Mice Mammals><Modern Man><Murine><Mus><Ménière's disease><Negotiating><Negotiation><Nerve><Nerve Cells><Nerve Degeneration><Nerve Fibers><Nerve Unit><Neural Cell><Neurocyte><Neuron Degeneration><Neurons><Neurophysiology - biologic function><Neurophysiology / Electrophysiology><Neurosciences><Noise><Noise-Induced Hearing Loss><Outer Hair Cells><P50 Mechanism><P50 Program><Pathway interactions><Patients><Pattern><Perceptual Disorders><Performance><Peripheral><Persons><Peyrone's Chloride><Peyrone's Salt><Pharmaceutical Preparations><Physiologic><Physiological><Platinum Diamminodichloride><Population><Presbyacusis><Presbycusis><Prevalence><Probabilistic Models><Probability Models><Psychophysics><Public Health><Recording of previous events><Records><Research><Ringing-Buzzing-Tinnitus><Risk Factors><Role><Sensorineural Deafness><Sensorineural Hearing Loss><Sensory><Sensory Hearing Loss><Sensory Neurons><Specialized Center><Speech><Speech Discrimination><Statistical Models><Study Subject><Synapses><Synaptic><Testing><Tinnitus><VIIIth Cranial Nerve><Vestibulocochlear Nerve><Work><age associated hearing loss><age induced hearing loss><age related decline in hearing><age related hearing deficits><age related hearing impairment><age related hearing loss><aging associated hearing loss><aging induced hearing loss><aging related decline in hearing><aging related hearing deficits><aging related hearing impairment><aging related hearing loss><auditory disease><auditory disorder><auditory dysfunction><auditory nerve><auditory problem><auditory tests><behavior study><behavioral study><bio-markers><biologic marker><biomarker><causation><cell damage><cell injury><cellular damage><cis dichlorodiammineplatinum><cis platinum compound><cis-Diaminedichloroplatinum><cis-Diamminedichloroplatinum><cis-Diamminedichloroplatinum(II)><cis-Dichlorodiammineplatinum(II)><cis-Platinum><clinical applicability><clinical application><cochlear synaptopathy><collaborative approach><damage to cells><data base><decreased loudness tolerance><design><designing><diagnostic ability><diagnostic approach><diagnostic biomarker><diagnostic capability><diagnostic marker><diagnostic power><diagnostic strategy><diagnostic utility><diagnostic value><disease causation><drug induced hearing impairment><drug induced hearing loss><drug/agent><dysfunctional hearing><ear hair cell><electrophysiological><handicapping><handicapping condition><hearing assessment><hearing challenged><hearing defect><hearing deficient><hearing deficit><hearing difficulty><hearing disease><hearing dysfunction><hearing impairment><hearing in noise><histories><human subject><injuries><injury to cells><inner ear><insight><loudness intolerance><model of animal><natural aging><necropsy><nerve damage><neural><neural degeneration><neural function><neurodegeneration><neurodegenerative><neurological degeneration><neuronal><neuronal degeneration><noise exposure><noise related hearing loss><noise sensitivity><noise-induced hearing impairment><normal aging><normative aging><ototoxic><ototoxicity><pathway><perception disorder><postmortem><psychophysical><public health relevance><regeneration based therapy><regeneration therapy><regenerative therapeutics><regenerative therapy><sensorineural hearing impairment><social role><sound><speech in background noise><speech in noise><speech in speech recognition><speech recognition><speech recognition in noise><statistical linear mixed models><statistical linear models><statistics><synapse>
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NIR J BARZILAI

ALBERT EINSTEIN COLLEGE OF MEDICINE, BRONX, NY

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$2,640,750
FY 2025

Project Title

Genetic variant-based drug discovery targeting conserved pathways of aging

Grant Number:

5U19AG056278-09

Activity Code:

U19

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2017

End Date:

8/31/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

ABSTRACT (OVERALL) Aging is the greatest risk factor for most common chronic human diseases and a logical target for developing interventions to prevent, mitigate or reverse multiple age-related morbidities. Over the past two decades, genetic and pharmacologic interventions targeting conserved pathw...

Research Terms

<100+ years old><AD pathology><Adult-Onset Diabetes Mellitus><Affect><Aging><Alzheimer's disease pathology><Alzheimer's pathology><Assay><Bioassay><Biological Assay><Bp50><CD40><CDW40><CRISPR><CRISPR/Cas system><Cancers><Candidate Disease Gene><Candidate Gene><Cardiovascular Diseases><Cell Aging><Cell Body><Cell Senescence><Cell model><Cells><Cellular Aging><Cellular Senescence><Cellular model><Centenarian><Chronic><Chronic Disease><Chronic Illness><Clinical><Clustered Regularly Interspaced Short Palindromic Repeats><Code><Coding System><Communities><DNA Damage><DNA Injury><DNA Resequencing><DNA Therapy><Data><Data Integration and Computation Core><Data Set><Development><Diabetes Mellitus><Disease><Disorder><Drug Kinetics><Drug Screening><Drug Targeting><Drug Therapy><Drugs><FDA approved><FKHR-Like 1><FKHRL1><FOXO3><FOXO3A><FOXO3A gene><FVB Mouse><Family Medical History><Family Medical History Epidemiology><Family history of><Flies><Forkhead Box O3A><Forkhead in Rhabdomyosarcoma-Like 1><Foundations><Freezing><Functional RNA><Funding><Gene Transfer Clinical><Gene variant><Generalized Growth><Genes><Genetic><Genetic Intervention><Genetic Screening><Genome><Genomics><Goals><Growth><Health><High Throughput Assay><Human><Human Engineering><Human Genetics><Hybrids><IGF1R><IGF1R gene><Immunoglobulin Enhancer-Binding Protein><In Vitro><Increase lifespan><Individual><Insulin-Like Growth Factor 1 Receptor Gene><Intermediary Metabolism><Intervention><Intervention Studies><Investigators><JV15-2><Ketosis-Resistant Diabetes Mellitus><Lead><Leadership><Length of Life><Link><Longevity><Longevity Pathway><MADH3><MADH3 gene><MGC9013><Malignant Neoplasms><Malignant Tumor><Maturity-Onset Diabetes Mellitus><Medication><Medicine><Metabolic Processes><Metabolism><Mice><Mice Mammals><Modeling><Modern Man><Morbidity><Morbidity - disease rate><Mothers Against Decapentaplegic, Drosophila, Homolog of, 3><Murine><Mus><NF-kB><NF-kappa B><NF-kappaB><NFKB><NIDDM><Natural Products><Nematoda><Nematodes><Nerve Degeneration><Neuron Degeneration><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noncoding RNA><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nontranslated RNA><Nuclear Factor kappa B><Nuclear Transcription Factor NF-kB><Organism-Level Process><Organismal Process><Outcome><PBMC><Pathway interactions><Pb element><Peripheral Blood Mononuclear Cell><Pharmaceutical Preparations><Pharmacokinetics><Pharmacological Treatment><Pharmacotherapy><Phenotype><Physiologic Processes><Physiological Processes><Process><R-Series Research Projects><R01 Mechanism><R01 Program><RNA Seq><RNA sequencing><RNAseq><Regimen><Replicative Senescence><Research><Research Grants><Research Personnel><Research Project Grants><Research Projects><Research Resources><Researchers><Resequencing><Resources><Risk Factors><Role><Route><SMA- and MAD-Related Protein 3><SMAD3><Slow-Onset Diabetes Mellitus><Specificity><Stable Diabetes Mellitus><T2 DM><T2D><T2DM><TNFRSF5><TNFRSF5 gene><Testing><Therapeutic><Tissue Growth><Transcription Factor NF-kB><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Untranslated RNA><Validation><Variant><Variation><Work><accelerated aging><accelerated biological age><accelerated biological aging><adult onset diabetes><age acceleration><age associated><age associated disease><age associated disorder><age associated impairment><age correlated><age dependent><age dependent disease><age dependent disorder><age dependent impairment><age linked><age related><age related human disease><age related pathways><age specific><age-related disease><age-related disorder><age-related impairment><aged><aged mice><aged mouse><aging associated><aging associated mechanism><aging mechanism><aging pathway><aging related><aging related mechanism><aging related pathways><allelic variant><appropriate dose><biological mechanism of age><biological pathways of age><boost longevity><build resilience><build resiliency><cardiovascular disorder><centenarian human (100+)><chronic disorder><cohort><college><collegiate><data integration><data integration core><data portal><data sharing><data sharing portal><depository><develop resilience><develop resiliency><develop therapy><developmental><diabetes><drug development><drug discovery><drug intervention><drug treatment><drug/agent><elderly mice><elongating the lifespan><enhance healthspan><enhance longevity><enhance resilience><enhance resiliency><exceptional human longevity><exceptional longevity in humans><exome><extend healthspan><extend life span><extend lifespan><extend longevity><extending healthy lifespan><extreme human longevity><extreme longevity in humans><facilitate resilience><fly><foster longevity><gene repair therapy><gene therapy><gene-based therapy><genetic analysis><genetic association><genetic information><genetic resource><genetic therapy><genetic variant><genomic therapy><genomic variant><healthspan><healthspan extension><healthy aging><healthy human aging><healthy life span><heavy metal Pb><heavy metal lead><high throughput screening><human derived pluripotent stem cell><human disease><human pluripotent stem cell><iPS><iPSC><iPSCs><improve healthspan><improve lifespan><improve longevity><improve resilience><improve resiliency><improved><in vivo><increase healthspan><increase resilience><increase resiliency><induced pluripotent cell><induced pluripotent stem cell><inducible pluripotent cell><inducible pluripotent stem cell><interdisciplinary approach><intervention development><intervention research><interventional research><interventional study><interventions research><kappa B Enhancer Binding Protein><ketosis resistant diabetes><late in life><late life><lifespan extension><low-frequency mutation><malignancy><maturity onset diabetes><mechanism regulating aging><mechanisms involved in aging><model organism><mouse genetics><mouse model><multidisciplinary approach><multimorbidity><multiple chronic conditions><murine model><naturally occurring product><neoplasm/cancer><neural degeneration><neurodegeneration><neurodegenerative><neurological degeneration><neuronal degeneration><new approaches><new drug target><new drug treatments><new druggable target><new drugs><new pharmacological therapeutic><new pharmacotherapy target><new therapeutic target><new therapeutics><new therapy><new therapy target><next generation therapeutics><noncoding><novel><novel approaches><novel drug target><novel drug treatments><novel druggable target><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel pharmacotherapy target><novel strategies><novel strategy><novel therapeutic target><novel therapeutics><novel therapy><novel therapy target><nuclear factor kappa beta><old mice><ontogeny><optimal drug dosage><optimal drug dose><p50><p65><pathway><pathway involved in aging><pharmaceutical intervention><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><polygenic predictors><polygenic scores><prevent><preventing><progenitor biology><progenitor cell biology><programs><prolong healthspan><prolong lifespan><prolong longevity><promote healthspan><promote lifespan><promote longevity><promote resilience><promote resiliency><rare allele><rare mutation><rare variant><replicative aging><repository><resilience development><response><roundworm><screening><screenings><small molecule><social role><stem><stem and progenitor biology><stem cell biology><stressor><success><support longevity><therapeutic target><therapy development><transcriptome sequencing><transcriptomic sequencing><transcriptomics><treatment development><type 2 DM><type II DM><type two diabetes><validations>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Paul D. Robbins

ALBERT EINSTEIN COLLEGE OF MEDICINE, BRONX, NY

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$2,640,750
FY 2025

Project Title

Genetic variant-based drug discovery targeting conserved pathways of aging

Grant Number:

5U19AG056278-09

Activity Code:

U19

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2017

End Date:

8/31/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

ABSTRACT (OVERALL) Aging is the greatest risk factor for most common chronic human diseases and a logical target for developing interventions to prevent, mitigate or reverse multiple age-related morbidities. Over the past two decades, genetic and pharmacologic interventions targeting conserved pathw...

Research Terms

<100+ years old><AD pathology><Adult-Onset Diabetes Mellitus><Affect><Aging><Alzheimer's disease pathology><Alzheimer's pathology><Assay><Bioassay><Biological Assay><Bp50><CD40><CDW40><CRISPR><CRISPR/Cas system><Cancers><Candidate Disease Gene><Candidate Gene><Cardiovascular Diseases><Cell Aging><Cell Body><Cell Senescence><Cell model><Cells><Cellular Aging><Cellular Senescence><Cellular model><Centenarian><Chronic><Chronic Disease><Chronic Illness><Clinical><Clustered Regularly Interspaced Short Palindromic Repeats><Code><Coding System><Communities><DNA Damage><DNA Injury><DNA Resequencing><DNA Therapy><Data><Data Integration and Computation Core><Data Set><Development><Diabetes Mellitus><Disease><Disorder><Drug Kinetics><Drug Screening><Drug Targeting><Drug Therapy><Drugs><FDA approved><FKHR-Like 1><FKHRL1><FOXO3><FOXO3A><FOXO3A gene><FVB Mouse><Family Medical History><Family Medical History Epidemiology><Family history of><Flies><Forkhead Box O3A><Forkhead in Rhabdomyosarcoma-Like 1><Foundations><Freezing><Functional RNA><Funding><Gene Transfer Clinical><Gene variant><Generalized Growth><Genes><Genetic><Genetic Intervention><Genetic Screening><Genome><Genomics><Goals><Growth><Health><High Throughput Assay><Human><Human Engineering><Human Genetics><Hybrids><IGF1R><IGF1R gene><Immunoglobulin Enhancer-Binding Protein><In Vitro><Increase lifespan><Individual><Insulin-Like Growth Factor 1 Receptor Gene><Intermediary Metabolism><Intervention><Intervention Studies><Investigators><JV15-2><Ketosis-Resistant Diabetes Mellitus><Lead><Leadership><Length of Life><Link><Longevity><Longevity Pathway><MADH3><MADH3 gene><MGC9013><Malignant Neoplasms><Malignant Tumor><Maturity-Onset Diabetes Mellitus><Medication><Medicine><Metabolic Processes><Metabolism><Mice><Mice Mammals><Modeling><Modern Man><Morbidity><Morbidity - disease rate><Mothers Against Decapentaplegic, Drosophila, Homolog of, 3><Murine><Mus><NF-kB><NF-kappa B><NF-kappaB><NFKB><NIDDM><Natural Products><Nematoda><Nematodes><Nerve Degeneration><Neuron Degeneration><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noncoding RNA><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nontranslated RNA><Nuclear Factor kappa B><Nuclear Transcription Factor NF-kB><Organism-Level Process><Organismal Process><Outcome><PBMC><Pathway interactions><Pb element><Peripheral Blood Mononuclear Cell><Pharmaceutical Preparations><Pharmacokinetics><Pharmacological Treatment><Pharmacotherapy><Phenotype><Physiologic Processes><Physiological Processes><Process><R-Series Research Projects><R01 Mechanism><R01 Program><RNA Seq><RNA sequencing><RNAseq><Regimen><Replicative Senescence><Research><Research Grants><Research Personnel><Research Project Grants><Research Projects><Research Resources><Researchers><Resequencing><Resources><Risk Factors><Role><Route><SMA- and MAD-Related Protein 3><SMAD3><Slow-Onset Diabetes Mellitus><Specificity><Stable Diabetes Mellitus><T2 DM><T2D><T2DM><TNFRSF5><TNFRSF5 gene><Testing><Therapeutic><Tissue Growth><Transcription Factor NF-kB><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Untranslated RNA><Validation><Variant><Variation><Work><accelerated aging><accelerated biological age><accelerated biological aging><adult onset diabetes><age acceleration><age associated><age associated disease><age associated disorder><age associated impairment><age correlated><age dependent><age dependent disease><age dependent disorder><age dependent impairment><age linked><age related><age related human disease><age related pathways><age specific><age-related disease><age-related disorder><age-related impairment><aged><aged mice><aged mouse><aging associated><aging associated mechanism><aging mechanism><aging pathway><aging related><aging related mechanism><aging related pathways><allelic variant><appropriate dose><biological mechanism of age><biological pathways of age><boost longevity><build resilience><build resiliency><cardiovascular disorder><centenarian human (100+)><chronic disorder><cohort><college><collegiate><data integration><data integration core><data portal><data sharing><data sharing portal><depository><develop resilience><develop resiliency><develop therapy><developmental><diabetes><drug development><drug discovery><drug intervention><drug treatment><drug/agent><elderly mice><elongating the lifespan><enhance healthspan><enhance longevity><enhance resilience><enhance resiliency><exceptional human longevity><exceptional longevity in humans><exome><extend healthspan><extend life span><extend lifespan><extend longevity><extending healthy lifespan><extreme human longevity><extreme longevity in humans><facilitate resilience><fly><foster longevity><gene repair therapy><gene therapy><gene-based therapy><genetic analysis><genetic association><genetic information><genetic resource><genetic therapy><genetic variant><genomic therapy><genomic variant><healthspan><healthspan extension><healthy aging><healthy human aging><healthy life span><heavy metal Pb><heavy metal lead><high throughput screening><human derived pluripotent stem cell><human disease><human pluripotent stem cell><iPS><iPSC><iPSCs><improve healthspan><improve lifespan><improve longevity><improve resilience><improve resiliency><improved><in vivo><increase healthspan><increase resilience><increase resiliency><induced pluripotent cell><induced pluripotent stem cell><inducible pluripotent cell><inducible pluripotent stem cell><interdisciplinary approach><intervention development><intervention research><interventional research><interventional study><interventions research><kappa B Enhancer Binding Protein><ketosis resistant diabetes><late in life><late life><lifespan extension><low-frequency mutation><malignancy><maturity onset diabetes><mechanism regulating aging><mechanisms involved in aging><model organism><mouse genetics><mouse model><multidisciplinary approach><multimorbidity><multiple chronic conditions><murine model><naturally occurring product><neoplasm/cancer><neural degeneration><neurodegeneration><neurodegenerative><neurological degeneration><neuronal degeneration><new approaches><new drug target><new drug treatments><new druggable target><new drugs><new pharmacological therapeutic><new pharmacotherapy target><new therapeutic target><new therapeutics><new therapy><new therapy target><next generation therapeutics><noncoding><novel><novel approaches><novel drug target><novel drug treatments><novel druggable target><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel pharmacotherapy target><novel strategies><novel strategy><novel therapeutic target><novel therapeutics><novel therapy><novel therapy target><nuclear factor kappa beta><old mice><ontogeny><optimal drug dosage><optimal drug dose><p50><p65><pathway><pathway involved in aging><pharmaceutical intervention><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><polygenic predictors><polygenic scores><prevent><preventing><progenitor biology><progenitor cell biology><programs><prolong healthspan><prolong lifespan><prolong longevity><promote healthspan><promote lifespan><promote longevity><promote resilience><promote resiliency><rare allele><rare mutation><rare variant><replicative aging><repository><resilience development><response><roundworm><screening><screenings><small molecule><social role><stem><stem and progenitor biology><stem cell biology><stressor><success><support longevity><therapeutic target><therapy development><transcriptome sequencing><transcriptomic sequencing><transcriptomics><treatment development><type 2 DM><type II DM><type two diabetes><validations>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

JAN VIJG

ALBERT EINSTEIN COLLEGE OF MEDICINE, BRONX, NY

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$2,640,750
FY 2025

Project Title

Genetic variant-based drug discovery targeting conserved pathways of aging

Grant Number:

5U19AG056278-09

Activity Code:

U19

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2017

End Date:

8/31/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

ABSTRACT (OVERALL) Aging is the greatest risk factor for most common chronic human diseases and a logical target for developing interventions to prevent, mitigate or reverse multiple age-related morbidities. Over the past two decades, genetic and pharmacologic interventions targeting conserved pathw...

Research Terms

<100+ years old><AD pathology><Adult-Onset Diabetes Mellitus><Affect><Aging><Alzheimer's disease pathology><Alzheimer's pathology><Assay><Bioassay><Biological Assay><Bp50><CD40><CDW40><CRISPR><CRISPR/Cas system><Cancers><Candidate Disease Gene><Candidate Gene><Cardiovascular Diseases><Cell Aging><Cell Body><Cell Senescence><Cell model><Cells><Cellular Aging><Cellular Senescence><Cellular model><Centenarian><Chronic><Chronic Disease><Chronic Illness><Clinical><Clustered Regularly Interspaced Short Palindromic Repeats><Code><Coding System><Communities><DNA Damage><DNA Injury><DNA Resequencing><DNA Therapy><Data><Data Integration and Computation Core><Data Set><Development><Diabetes Mellitus><Disease><Disorder><Drug Kinetics><Drug Screening><Drug Targeting><Drug Therapy><Drugs><FDA approved><FKHR-Like 1><FKHRL1><FOXO3><FOXO3A><FOXO3A gene><FVB Mouse><Family Medical History><Family Medical History Epidemiology><Family history of><Flies><Forkhead Box O3A><Forkhead in Rhabdomyosarcoma-Like 1><Foundations><Freezing><Functional RNA><Funding><Gene Transfer Clinical><Gene variant><Generalized Growth><Genes><Genetic><Genetic Intervention><Genetic Screening><Genome><Genomics><Goals><Growth><Health><High Throughput Assay><Human><Human Engineering><Human Genetics><Hybrids><IGF1R><IGF1R gene><Immunoglobulin Enhancer-Binding Protein><In Vitro><Increase lifespan><Individual><Insulin-Like Growth Factor 1 Receptor Gene><Intermediary Metabolism><Intervention><Intervention Studies><Investigators><JV15-2><Ketosis-Resistant Diabetes Mellitus><Lead><Leadership><Length of Life><Link><Longevity><Longevity Pathway><MADH3><MADH3 gene><MGC9013><Malignant Neoplasms><Malignant Tumor><Maturity-Onset Diabetes Mellitus><Medication><Medicine><Metabolic Processes><Metabolism><Mice><Mice Mammals><Modeling><Modern Man><Morbidity><Morbidity - disease rate><Mothers Against Decapentaplegic, Drosophila, Homolog of, 3><Murine><Mus><NF-kB><NF-kappa B><NF-kappaB><NFKB><NIDDM><Natural Products><Nematoda><Nematodes><Nerve Degeneration><Neuron Degeneration><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noncoding RNA><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Nontranslated RNA><Nuclear Factor kappa B><Nuclear Transcription Factor NF-kB><Organism-Level Process><Organismal Process><Outcome><PBMC><Pathway interactions><Pb element><Peripheral Blood Mononuclear Cell><Pharmaceutical Preparations><Pharmacokinetics><Pharmacological Treatment><Pharmacotherapy><Phenotype><Physiologic Processes><Physiological Processes><Process><R-Series Research Projects><R01 Mechanism><R01 Program><RNA Seq><RNA sequencing><RNAseq><Regimen><Replicative Senescence><Research><Research Grants><Research Personnel><Research Project Grants><Research Projects><Research Resources><Researchers><Resequencing><Resources><Risk Factors><Role><Route><SMA- and MAD-Related Protein 3><SMAD3><Slow-Onset Diabetes Mellitus><Specificity><Stable Diabetes Mellitus><T2 DM><T2D><T2DM><TNFRSF5><TNFRSF5 gene><Testing><Therapeutic><Tissue Growth><Transcription Factor NF-kB><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><Untranslated RNA><Validation><Variant><Variation><Work><accelerated aging><accelerated biological age><accelerated biological aging><adult onset diabetes><age acceleration><age associated><age associated disease><age associated disorder><age associated impairment><age correlated><age dependent><age dependent disease><age dependent disorder><age dependent impairment><age linked><age related><age related human disease><age related pathways><age specific><age-related disease><age-related disorder><age-related impairment><aged><aged mice><aged mouse><aging associated><aging associated mechanism><aging mechanism><aging pathway><aging related><aging related mechanism><aging related pathways><allelic variant><appropriate dose><biological mechanism of age><biological pathways of age><boost longevity><build resilience><build resiliency><cardiovascular disorder><centenarian human (100+)><chronic disorder><cohort><college><collegiate><data integration><data integration core><data portal><data sharing><data sharing portal><depository><develop resilience><develop resiliency><develop therapy><developmental><diabetes><drug development><drug discovery><drug intervention><drug treatment><drug/agent><elderly mice><elongating the lifespan><enhance healthspan><enhance longevity><enhance resilience><enhance resiliency><exceptional human longevity><exceptional longevity in humans><exome><extend healthspan><extend life span><extend lifespan><extend longevity><extending healthy lifespan><extreme human longevity><extreme longevity in humans><facilitate resilience><fly><foster longevity><gene repair therapy><gene therapy><gene-based therapy><genetic analysis><genetic association><genetic information><genetic resource><genetic therapy><genetic variant><genomic therapy><genomic variant><healthspan><healthspan extension><healthy aging><healthy human aging><healthy life span><heavy metal Pb><heavy metal lead><high throughput screening><human derived pluripotent stem cell><human disease><human pluripotent stem cell><iPS><iPSC><iPSCs><improve healthspan><improve lifespan><improve longevity><improve resilience><improve resiliency><improved><in vivo><increase healthspan><increase resilience><increase resiliency><induced pluripotent cell><induced pluripotent stem cell><inducible pluripotent cell><inducible pluripotent stem cell><interdisciplinary approach><intervention development><intervention research><interventional research><interventional study><interventions research><kappa B Enhancer Binding Protein><ketosis resistant diabetes><late in life><late life><lifespan extension><low-frequency mutation><malignancy><maturity onset diabetes><mechanism regulating aging><mechanisms involved in aging><model organism><mouse genetics><mouse model><multidisciplinary approach><multimorbidity><multiple chronic conditions><murine model><naturally occurring product><neoplasm/cancer><neural degeneration><neurodegeneration><neurodegenerative><neurological degeneration><neuronal degeneration><new approaches><new drug target><new drug treatments><new druggable target><new drugs><new pharmacological therapeutic><new pharmacotherapy target><new therapeutic target><new therapeutics><new therapy><new therapy target><next generation therapeutics><noncoding><novel><novel approaches><novel drug target><novel drug treatments><novel druggable target><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel pharmacotherapy target><novel strategies><novel strategy><novel therapeutic target><novel therapeutics><novel therapy><novel therapy target><nuclear factor kappa beta><old mice><ontogeny><optimal drug dosage><optimal drug dose><p50><p65><pathway><pathway involved in aging><pharmaceutical intervention><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><polygenic predictors><polygenic scores><prevent><preventing><progenitor biology><progenitor cell biology><programs><prolong healthspan><prolong lifespan><prolong longevity><promote healthspan><promote lifespan><promote longevity><promote resilience><promote resiliency><rare allele><rare mutation><rare variant><replicative aging><repository><resilience development><response><roundworm><screening><screenings><small molecule><social role><stem><stem and progenitor biology><stem cell biology><stressor><success><support longevity><therapeutic target><therapy development><transcriptome sequencing><transcriptomic sequencing><transcriptomics><treatment development><type 2 DM><type II DM><type two diabetes><validations>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Joann B. Sweasy

UNIVERSITY OF NEBRASKA MEDICAL CENTER, OMAHA, NE

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$2,593,786
FY 2025

Project Title

Buffett Cancer Center Support Grant

Grant Number:

5P30CA036727-39

Activity Code:

P30

Mechanism:

Research Centers

Agency:

NIH

Start Date:

9/5/1997

End Date:

8/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY The Fred & Pamela Buffett Cancer Center (Buffett Cancer Center or BCC), an NCI-designated Cancer Center since 1984, is committed to basic, translational, clinical and population science research, comprehensive educational programs, and outreach to underserved communities in our catch...

Research Terms

<Address><Award><Basic Research><Basic Science><Biological Markers><CCSG><Cancer Biology><Cancer Burden><Cancer Center><Cancer Center Support Grant><Cancer Control><Cancer Control Science><Cancers><Catchment Area><Clinical><Clinical Cancer Center><Clinical Research><Clinical Sciences><Clinical Study><Clinical Trials><Communities><Community Outreach><Development><Direct Costs><Early Diagnosis><Education><Education and Training><Educational aspects><Environment><Faculty Education><Faculty Training><Fostering><Funding><GI cancers><GI malignancies><GI tract cancers><Gastrointestinal Cancer><Gastrointestinal Tract Cancer><Health Care><Health Care Facility><Health Facilities><Intervention><Leadership><Malignant Gastrointestinal Neoplasm><Malignant Neoplasms><Malignant Tumor><Malignant neoplasm of gastrointestinal tract><Medical center><Medicinal Chemistry><Medicine><Mission><Modeling><NCI-Designated Cancer Center><Names><National Cancer Burden><Nebraska><Organoids><Patients><Pharmaceutic Chemistry><Pharmaceutical Chemistry><Physicians><Population Sciences><Position><Positioning Attribute><Prevention><Prognosis><Reporting><Research><Research Infrastructure><Research Peer Review><Research Resources><Research Support><Resource Sharing><Resources><Risk><Role><Scientific Advances and Accomplishments><Synthesis Chemistry><Synthetic Chemistry><Teacher Education><Teacher Educator><Teacher Preparation><Teacher Professional Development><Teacher Training><Tissue Arrays><Tissue Chip><Tissue Microarray><Training and Education><Translational Research><Translational Science><Universities><anti-cancer research><bio-markers><biologic marker><biomarker><cancer care><cancer disparity><cancer education><cancer health disparity><cancer initiation><cancer progression><cancer research><cancer-related health disparity><care facilities><clinical care><community engagement><community partners><community-based partners><computational chemistry><developmental><disparity in cancer><disparity in health><early detection><engagement with communities><faculty development><faculty professional development><gastrointestinal malignancies><health disparity><innovate><innovation><innovative><instructor training><interdisciplinary collaboration><malignancy><member><metabolism measurement><metabolomics><metabonomics><multidisciplinary><name><named><naming><neoplasm progression><neoplasm/cancer><neoplastic progression><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><outreach><patient centered><patient oriented><pre-clinical imaging><preclinical imaging><programs><recruit><research facility><scientific accomplishments><scientific advances><social role><teacher development><transdisciplinary collaboration><translation research><translational cancer research><translational investigation><tumor progression><under served community><underserved community>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Lisa Blake Haddad

POPULATION COUNCIL, NEW YORK, NY

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$2,281,160
FY 2025

Project Title

Contraception development research center to advance a novel intravaginal ring as a non-hormonal multipurpose prevention technology

Grant Number:

5P50HD106793-05

Activity Code:

P50

Mechanism:

Research Centers

Agency:

NIH

Start Date:

9/22/2021

End Date:

8/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

OVERALL – ABSTRACT The overarching goal of the Population Council’s (PC) P50 proposal is to develop an innovative non-hormonal multipurpose prevention technology (MPT) intravaginal ring (IVR) with the potential to improve the lives of millions of women globally by combatting the overlapping burdens ...

Research Terms

<AIDS Virus><AIDS prevention><Acquired Immune Deficiency Syndrome Virus><Acquired Immunodeficiency Syndrome Virus><Adherence><Advanced Development><Advisory Committees><Anti-Bacterial Agents><Bacterial Vaginitis><Bacterial Vaginosis><Basic Research><Basic Science><Behavioral Sciences><Biomedical Research><Business-Friendly Atmosphere><Cannot achieve a pregnancy><Characteristics><Child Health><Chlamydia><Clinical Trials><Contraception><Contraceptive Agents><Contraceptive methods><Contraceptives><Copper><Cross Sectional Analysis><Cross-Over Studies><Cross-Sectional Analyses><Cross-Sectional Studies><Cross-Sectional Survey><Crossover Studies><Cu element><Data><Development><Development Plans><Development and Research><Difficulty conceiving><Dimensions><Disease Frequency Surveys><Dose><Drug Delivery><Drug Delivery Systems><Drug Kinetics><Drug Precursors><Endocrine Gland Secretion><Ensure><Evaluation><Failure><Fellowship><Female Health><Fertility Control><Formulation><Fostering><Funding><Gestation><Goals><Gonococcal Infection><Gonorrhea><Good Manufacturing Process><Good manufacturing practice><Grant><HHV-2><HHV2><HIV><HIV Prevention><HIV-1><HIV-I><HIV/AIDS prevention><HIV1><HSV-2><HSV2><Health><Herpes Simplex Virus 2><Herpes Simplex Virus Type 2><Herpesvirus 2 (alpha), Human><Herpesvirus progenitalis><Hormones><Human><Human (alpha) herpes virus 2><Human Herpesvirus 2><Human Immunodeficiency Virus Type 1><Human Immunodeficiency Viruses><Human herpes simplex virus type 2><Human immunodeficiency virus 1><In Vitro><Industry><Infertility><Inhibition of Fertilization><Institution><Investigational Drugs><Investigational New Drugs><Investigators><Investments><LAV-HTLV-III><Lactic acid><Lead><Lymphadenopathy-Associated Virus><M mulatta><M. mulatta><Macaca mulatta><Macaca rhesus><Marketing><Maternal Mortality><Maternal and Child Health><Mechanics><Medical><Menses><Menstruation><Methods><Miyagawanella><Modern Man><Multipurpose prevention technology><NICHD><National Institute of Child Health and Human Development><Nonspecific Vaginitis><Ovine><Ovis><Pathway interactions><Pb element><Performance><Persons><Pharmaceutical Agent><Pharmaceuticals><Pharmacokinetics><Pharmacologic Actions><Pharmacologic Substance><Pharmacological Substance><Pilot Projects><Polymers><Population><Pregnancy><Premature Birth><Prematurely delivering><Preterm Birth><Prevention><Prevention Research><Pro-Drugs><Prodrugs><Production><Property><R & D><R&D><R-Series Research Projects><R01 Mechanism><R01 Program><Regulatory Affairs><Reproductive Health><Research><Research Grants><Research Personnel><Research Project Grants><Research Projects><Researchers><Rhesus Macaque><Rhesus Monkey><Risk><Safety><Science><Sexually Transmitted Diseases><Sexually Transmitted Disorder><Sexually Transmitted Infection><Sheep><Side><Social Sciences><Sperm><Spermatozoa><Task Forces><Technology><Temperature><Testing><Therapeutic Hormone><Toxic effect><Toxicities><Unplanned pregnancy><Vagina><Vaginal Ring><Venereal Diseases><Venereal Disorders><Venereal Infections><Viral><Virus-HIV><Woman><Women's Health><Work><Zinc><Zinc Acetate><Zn element><advisory team><anti-bacterial><anti-microbial><antimicrobial><bedsonia><business-friendly environment><candidate selection><career><chronic pelvic floor pain><chronic pelvic pain><chronic pelvic pain syndrome><collaborative atmosphere><collaborative environment><combat><community engagement><contraceptive efficacy><design><designing><developmental><engagement with communities><experience><experiment><experimental research><experimental study><experiments><fertility cessation><fertility loss><health goals><heavy metal Pb><heavy metal lead><herpes simplex ii><human alphaherpesvirus 2><improved><in vivo><infertile><innovate><innovation><innovative><interactive atmosphere><interactive environment><interdisciplinary atmosphere><interdisciplinary environment><interest><intravaginal ring><manufacture><maternal death><mechanic><mechanical><menstrual period><monthly period><monthly periods><multipurpose prevention><non-specific vaginitis><novel><pathway><peer-group atmosphere><peer-group environment><pelvic myofascial pain><pharmaceutical><pilot study><polymer><polymeric><pre-clinical study><preclinical study><premature childbirth><premature delivery><preterm delivery><prevent><preventing><product development><prototype><public health priorities><research and development><safety study><sensor><sexually acquired infection><sperm cell><success><synergism><tech development><technology development><timeline><unintended pregnancy><zoosperm>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

MIGUEL HERNAN

MCLEAN HOSPITAL, BELMONT, MA

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,969,525
FY 2025

Project Title

Laboratory for Early Psychosis Research (LEAP)

Grant Number:

5P50MH115846-07

Activity Code:

P50

Mechanism:

Research Centers

Agency:

NIH

Start Date:

5/15/2019

End Date:

6/30/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

1. Abstract We propose to continue our existing NIMH P50 ALACRITY Center (Laboratory for Early Psychosis or LEAP Center). Although coordinated specialty care (CSC) is standard of care for patients with first episode psychosis (FEP), there remain gaps in our knowledge base regarding selection and dep...

Research Terms

<Address><Adverse effects><Advocate><Antipsychotic Agents><Antipsychotic Drugs><Antipsychotics><Benchmarking><Best Practice Analysis><Binding><Caring><Clinic><Clinical Data><Clinical Research><Clinical Study><Clinical Trials><Cognitive remediation><Collaborations><Comparative Effectiveness Research><Complement><Complement Proteins><Coordinated Specialty Care><Country><Data><Data Collection><Data Science><Data Set><Data Sources><Dedications><Development><Discipline><Disease><Disorder><Drug Therapy><Economics><Effectiveness><Electronic Health Record><Epidemiology><Equity><Evolution><Face><Faculty><Family><Funding><Future><Goals><Health Care Systems><Health Policy><Health system><Heterogeneity><Infrastructure><Injectable><Inpatients><International><Intervention><Laboratories><Learning><Machine Learning><Major Tranquilizers><Major Tranquilizing Agents><Massachusetts><Mental Health><Mental Hygiene><Methods><Modernization><Molecular Interaction><NIMH><National Institute of Mental Health><Neuroleptic Agents><Neuroleptic Drugs><Neuroleptics><North America><Operations Research><Patient Care><Patient Care Delivery><Patients><Pharmacological Treatment><Pharmacotherapy><Pilot Projects><Policies><Policy Maker><Provider><Psychiatry><Psychological Health><Psychotic Disorders><Publishing><Randomized, Controlled Trials><Registries><Research><Research Design><Research Methodology><Research Methods><Role><Schizophrenia><Schizophrenic Disorders><Science><Scientist><Site><Source><Standardization><Strategic Planning><Study Type><Sum><System><Techniques><Testing><Training><Work><analytical method><benchmark><care for patients><care of patients><care services><care systems><caring for patients><clinical care><clinical predictors><complementation><data diversity><data driven platform><data harmonization><data platform><data registry><data standardization><data standards><dementia praecox><design><designing><developmental><digital><diverse data><drug intervention><drug treatment><early psychosis><economic><electronic health care record><electronic health data><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><epidemiologic><epidemiological><faces><facial><first episode psychosis><harmonized data><health care policy><improved><innovate><innovation><innovative><interdisciplinary collaboration><knowledge base><machine based learning><multiple data types><outreach><participant engagement><patient engagement><peer><pharmaceutical intervention><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><pilot study><psychotic illness><randomized control trial><randomized, clinical trials><research and methods><schizophrenic><social role><standard of care><statistics><study design><transdisciplinary collaboration><treatment effect><trial design>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

JOHN HSU

MCLEAN HOSPITAL, BELMONT, MA

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,969,525
FY 2025

Project Title

Laboratory for Early Psychosis Research (LEAP)

Grant Number:

5P50MH115846-07

Activity Code:

P50

Mechanism:

Research Centers

Agency:

NIH

Start Date:

5/15/2019

End Date:

6/30/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

1. Abstract We propose to continue our existing NIMH P50 ALACRITY Center (Laboratory for Early Psychosis or LEAP Center). Although coordinated specialty care (CSC) is standard of care for patients with first episode psychosis (FEP), there remain gaps in our knowledge base regarding selection and dep...

Research Terms

<Address><Adverse effects><Advocate><Antipsychotic Agents><Antipsychotic Drugs><Antipsychotics><Benchmarking><Best Practice Analysis><Binding><Caring><Clinic><Clinical Data><Clinical Research><Clinical Study><Clinical Trials><Cognitive remediation><Collaborations><Comparative Effectiveness Research><Complement><Complement Proteins><Coordinated Specialty Care><Country><Data><Data Collection><Data Science><Data Set><Data Sources><Dedications><Development><Discipline><Disease><Disorder><Drug Therapy><Economics><Effectiveness><Electronic Health Record><Epidemiology><Equity><Evolution><Face><Faculty><Family><Funding><Future><Goals><Health Care Systems><Health Policy><Health system><Heterogeneity><Infrastructure><Injectable><Inpatients><International><Intervention><Laboratories><Learning><Machine Learning><Major Tranquilizers><Major Tranquilizing Agents><Massachusetts><Mental Health><Mental Hygiene><Methods><Modernization><Molecular Interaction><NIMH><National Institute of Mental Health><Neuroleptic Agents><Neuroleptic Drugs><Neuroleptics><North America><Operations Research><Patient Care><Patient Care Delivery><Patients><Pharmacological Treatment><Pharmacotherapy><Pilot Projects><Policies><Policy Maker><Provider><Psychiatry><Psychological Health><Psychotic Disorders><Publishing><Randomized, Controlled Trials><Registries><Research><Research Design><Research Methodology><Research Methods><Role><Schizophrenia><Schizophrenic Disorders><Science><Scientist><Site><Source><Standardization><Strategic Planning><Study Type><Sum><System><Techniques><Testing><Training><Work><analytical method><benchmark><care for patients><care of patients><care services><care systems><caring for patients><clinical care><clinical predictors><complementation><data diversity><data driven platform><data harmonization><data platform><data registry><data standardization><data standards><dementia praecox><design><designing><developmental><digital><diverse data><drug intervention><drug treatment><early psychosis><economic><electronic health care record><electronic health data><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><epidemiologic><epidemiological><faces><facial><first episode psychosis><harmonized data><health care policy><improved><innovate><innovation><innovative><interdisciplinary collaboration><knowledge base><machine based learning><multiple data types><outreach><participant engagement><patient engagement><peer><pharmaceutical intervention><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><pilot study><psychotic illness><randomized control trial><randomized, clinical trials><research and methods><schizophrenic><social role><standard of care><statistics><study design><transdisciplinary collaboration><treatment effect><trial design>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Dost Ongur

MCLEAN HOSPITAL, BELMONT, MA

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,969,525
FY 2025

Project Title

Laboratory for Early Psychosis Research (LEAP)

Grant Number:

5P50MH115846-07

Activity Code:

P50

Mechanism:

Research Centers

Agency:

NIH

Start Date:

5/15/2019

End Date:

6/30/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

1. Abstract We propose to continue our existing NIMH P50 ALACRITY Center (Laboratory for Early Psychosis or LEAP Center). Although coordinated specialty care (CSC) is standard of care for patients with first episode psychosis (FEP), there remain gaps in our knowledge base regarding selection and dep...

Research Terms

<Address><Adverse effects><Advocate><Antipsychotic Agents><Antipsychotic Drugs><Antipsychotics><Benchmarking><Best Practice Analysis><Binding><Caring><Clinic><Clinical Data><Clinical Research><Clinical Study><Clinical Trials><Cognitive remediation><Collaborations><Comparative Effectiveness Research><Complement><Complement Proteins><Coordinated Specialty Care><Country><Data><Data Collection><Data Science><Data Set><Data Sources><Dedications><Development><Discipline><Disease><Disorder><Drug Therapy><Economics><Effectiveness><Electronic Health Record><Epidemiology><Equity><Evolution><Face><Faculty><Family><Funding><Future><Goals><Health Care Systems><Health Policy><Health system><Heterogeneity><Infrastructure><Injectable><Inpatients><International><Intervention><Laboratories><Learning><Machine Learning><Major Tranquilizers><Major Tranquilizing Agents><Massachusetts><Mental Health><Mental Hygiene><Methods><Modernization><Molecular Interaction><NIMH><National Institute of Mental Health><Neuroleptic Agents><Neuroleptic Drugs><Neuroleptics><North America><Operations Research><Patient Care><Patient Care Delivery><Patients><Pharmacological Treatment><Pharmacotherapy><Pilot Projects><Policies><Policy Maker><Provider><Psychiatry><Psychological Health><Psychotic Disorders><Publishing><Randomized, Controlled Trials><Registries><Research><Research Design><Research Methodology><Research Methods><Role><Schizophrenia><Schizophrenic Disorders><Science><Scientist><Site><Source><Standardization><Strategic Planning><Study Type><Sum><System><Techniques><Testing><Training><Work><analytical method><benchmark><care for patients><care of patients><care services><care systems><caring for patients><clinical care><clinical predictors><complementation><data diversity><data driven platform><data harmonization><data platform><data registry><data standardization><data standards><dementia praecox><design><designing><developmental><digital><diverse data><drug intervention><drug treatment><early psychosis><economic><electronic health care record><electronic health data><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><epidemiologic><epidemiological><faces><facial><first episode psychosis><harmonized data><health care policy><improved><innovate><innovation><innovative><interdisciplinary collaboration><knowledge base><machine based learning><multiple data types><outreach><participant engagement><patient engagement><peer><pharmaceutical intervention><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><pilot study><psychotic illness><randomized control trial><randomized, clinical trials><research and methods><schizophrenic><social role><standard of care><statistics><study design><transdisciplinary collaboration><treatment effect><trial design>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Sarki A. Abdulkadir

NORTHWESTERN UNIVERSITY, CHICAGO, IL

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,881,134
FY 2025

Project Title

SPORE in Prostate Cancer

Grant Number:

5P50CA180995-10

Activity Code:

P50

Mechanism:

Research Centers

Agency:

NIH

Start Date:

8/18/2015

End Date:

7/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

OVERALL: ABSTRACT This application is a request for renewal funding of the SPORE in Prostate Cancer P50 CA180995 at the Robert H. Lurie Comprehensive Cancer Center of Northwestern University in collaboration with the University of Chicago Comprehensive Cancer Center and NorthShore University HealthS...

Research Terms

<1-Phosphatidylinositol 3-Kinase><Advocacy><Advocate><Aggressive course><American male><American man><American men><Antibody Therapy><Antitumor Response><Basic Research><Basic Science><Bioinformatics><Biology><Biometrics><Biometry><Biopsy Sample><Biopsy Specimen><Biostatistics><Blood Sample><Blood specimen><Body Tissues><Cancer Cause><Cancer Etiology><Cancer Patient><Catchment Area><Cell Communication and Signaling><Cell Signaling><Chicago><Class I Genes><Clinical><Clinical Sciences><Clinical Trials><Collaborations><Combined Modality Therapy><Comprehensive Cancer Center><Core Facility><DNA Damage><DNA Injury><Dedications><Development><Diagnosis><Disease><Disorder><Early-Stage Clinical Trials><FDA approved><Family member><Focus Groups><Friends><Funding><Gene Transcription><Genetic Transcription><Health><Health system><Human><IND Filing><IND application><IND package><IND submission><Immune mediated therapy><Immune system><Immunologically Directed Therapy><Immunotherapy><Infrastructure><Innovative Therapy><Institution><Intracellular Communication and Signaling><Investigational New Drug Application><Investigators><Leadership><MHC Class I><MHC Class I Genes><MMAC1><MMAC1 protein><Malignant neoplasm of prostate><Malignant prostatic tumor><Measurable><Measures><Mediating><Metastatic Prostate Cancer><Modern Man><Multimodal Therapy><Multimodal Treatment><Mutated in Multiple Advanced Cancers 1><Myelogenous><Myeloid><NCI Organization><National Cancer Institute><Oncogenic><PARP Inhibitor><PARP-1 inhibitor><PARPi><PD 1><PD-1><PD1><PHTS gene><PHTS protein><PI-3 Kinase><PI3-Kinase><PI3CG><PI3KGamma><PI3k><PIK3><PIK3CG><PIK3CG gene><PSA Assay><PTEN><PTEN gene><PTEN protein><PTEN1><Pathologist><Pathway interactions><Patient Care><Patient Care Delivery><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Pharmaceutical Agent><Pharmaceuticals><Pharmacologic Substance><Pharmacological Substance><Phase 1 Clinical Trials><Phase I Clinical Trials><Phosphatase and Tensin Homolog><Phosphatase and Tensin Homolog Deleted on Chromosome 10><Phosphatidylinositol 3-Kinase><Phosphatidylinositol-3-OH Kinase><Phosphoinositide 3-Hydroxykinase><Phosphorylation><Poly(ADP-ribose) Polymerase Inhibitor><Poly(ADP-ribose) polymerase 1 inhibitor><Pre IND FDA meeting><Pre-Clinical Model><Pre-IND mtg><Preclinical Models><Prostate CA><Prostate Cancer><Prostate Carcinoma Metastatic><Prostate Specific Antigen Assay><Prostate malignancy><Prostate specific antigen measurement><Protein Phosphorylation><PtdIns 3-Kinase><QOL><Qualifying><Quality of life><R-Series Research Projects><R01 Mechanism><R01 Program><RNA Expression><Regulation><Research><Research Grants><Research Personnel><Research Project Grants><Research Projects><Researchers><Resistance><Role of Tob in T-cell activation><STING agonists><Scientist><Signal Transduction><Signal Transduction Systems><Signaling><Source><T cell infiltration><T-Cell Activation Pathway><Talents><Testing><Therapeutic><Tissues><Transcription><Translating><Translational Research><Translational Science><Translations><Treatment Efficacy><Type I Phosphatidylinositol Kinase><Type III Phosphoinositide 3-Kinase><U.S. Males><US Men><US male><Universities><Visceral><Work><androgen independent prostate cancer><androgen indifferent prostate cancer><androgen insensitive prostate cancer><androgen resistance in prostate cancer><androgen resistant prostate cancer><anti-cancer research><anti-tumor response><antibody based therapies><antibody treatment><antibody-based therapeutics><antibody-based treatment><biological signal transduction><bone><c myc><c-myc Genes><cancer genetics><cancer microenvironment><cancer research><care for patients><care of patients><career><caring for patients><castration resistant CaP><castration resistant PCa><castration resistant prostate cancer><check point blockade><checkpoint blockade><cmyc><cohort><combination therapy><combined modality treatment><combined treatment><design><designing><determine efficacy><developmental><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><evaluate efficacy><examine efficacy><experience><experiment><experimental research><experimental study><experiments><hormone refractory prostate cancer><humanized monoclonal antibodies><immune check point blockade><immune checkpoint blockade><immune microenvironment><immune therapeutic approach><immune therapeutic interventions><immune therapeutic regimens><immune therapeutic strategy><immune therapy><immune-based therapies><immune-based treatments><immuno therapy><immunosuppressive microenvironment><immunosuppressive tumor microenvironment><improved><improved outcome><inhibitor><innovate><innovation><innovative><intervention efficacy><investigator-initiated trial><males in America><males in the U.S.><males in the US><males in the USA><males in the United States><member><men><men in America><men in the U.S.><men in the US><men in the USA><men in the United States><mortality><mouse model><multi-modal therapy><multi-modal treatment><murine model><mutated in multiple advanced cancers 1 protein><new approaches><new drug treatments><new drugs><new pharmacological therapeutic><new technology><new therapeutics><new therapy><next generation therapeutics><novel><novel approaches><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel strategies><novel strategy><novel technologies><novel therapeutics><novel therapy><pathway><patient oriented outcomes><patient population><pharmaceutical><phase I protocol><phosphatase and tensin homologue on chromosome ten><pre-IND consultation><pre-IND discussion><pre-IND meeting><pre-Investigational New Drug meeting><pre-clinical study><preclinical study><programmed cell death 1><programmed cell death protein 1><programmed death 1><programs><prostate cancer model><prostate cancer resistant to androgen><prostate tumor model><recruit><rejuvenating intervention><rejuvenation approach><rejuvenation strategies><rejuvenation therapy><rejuvenation treatment><resistant><safety study><sle2><success><systemic lupus erythematosus susceptibility 2><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment><therapeutic efficacy><therapeutic rejuvenation><therapy efficacy><translation><translation research><translational investigation><tumor><tumor immune microenvironment><tumor microenvironment><tumor-immune system interactions><v-myc Avian Myelocytomatosis Viral Oncogene Cellular Homolog>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

MAHA H HUSSAIN

NORTHWESTERN UNIVERSITY, CHICAGO, IL

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,881,134
FY 2025

Project Title

SPORE in Prostate Cancer

Grant Number:

5P50CA180995-10

Activity Code:

P50

Mechanism:

Research Centers

Agency:

NIH

Start Date:

8/18/2015

End Date:

7/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

OVERALL: ABSTRACT This application is a request for renewal funding of the SPORE in Prostate Cancer P50 CA180995 at the Robert H. Lurie Comprehensive Cancer Center of Northwestern University in collaboration with the University of Chicago Comprehensive Cancer Center and NorthShore University HealthS...

Research Terms

<1-Phosphatidylinositol 3-Kinase><Advocacy><Advocate><Aggressive course><American male><American man><American men><Antibody Therapy><Antitumor Response><Basic Research><Basic Science><Bioinformatics><Biology><Biometrics><Biometry><Biopsy Sample><Biopsy Specimen><Biostatistics><Blood Sample><Blood specimen><Body Tissues><Cancer Cause><Cancer Etiology><Cancer Patient><Catchment Area><Cell Communication and Signaling><Cell Signaling><Chicago><Class I Genes><Clinical><Clinical Sciences><Clinical Trials><Collaborations><Combined Modality Therapy><Comprehensive Cancer Center><Core Facility><DNA Damage><DNA Injury><Dedications><Development><Diagnosis><Disease><Disorder><Early-Stage Clinical Trials><FDA approved><Family member><Focus Groups><Friends><Funding><Gene Transcription><Genetic Transcription><Health><Health system><Human><IND Filing><IND application><IND package><IND submission><Immune mediated therapy><Immune system><Immunologically Directed Therapy><Immunotherapy><Infrastructure><Innovative Therapy><Institution><Intracellular Communication and Signaling><Investigational New Drug Application><Investigators><Leadership><MHC Class I><MHC Class I Genes><MMAC1><MMAC1 protein><Malignant neoplasm of prostate><Malignant prostatic tumor><Measurable><Measures><Mediating><Metastatic Prostate Cancer><Modern Man><Multimodal Therapy><Multimodal Treatment><Mutated in Multiple Advanced Cancers 1><Myelogenous><Myeloid><NCI Organization><National Cancer Institute><Oncogenic><PARP Inhibitor><PARP-1 inhibitor><PARPi><PD 1><PD-1><PD1><PHTS gene><PHTS protein><PI-3 Kinase><PI3-Kinase><PI3CG><PI3KGamma><PI3k><PIK3><PIK3CG><PIK3CG gene><PSA Assay><PTEN><PTEN gene><PTEN protein><PTEN1><Pathologist><Pathway interactions><Patient Care><Patient Care Delivery><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Pharmaceutical Agent><Pharmaceuticals><Pharmacologic Substance><Pharmacological Substance><Phase 1 Clinical Trials><Phase I Clinical Trials><Phosphatase and Tensin Homolog><Phosphatase and Tensin Homolog Deleted on Chromosome 10><Phosphatidylinositol 3-Kinase><Phosphatidylinositol-3-OH Kinase><Phosphoinositide 3-Hydroxykinase><Phosphorylation><Poly(ADP-ribose) Polymerase Inhibitor><Poly(ADP-ribose) polymerase 1 inhibitor><Pre IND FDA meeting><Pre-Clinical Model><Pre-IND mtg><Preclinical Models><Prostate CA><Prostate Cancer><Prostate Carcinoma Metastatic><Prostate Specific Antigen Assay><Prostate malignancy><Prostate specific antigen measurement><Protein Phosphorylation><PtdIns 3-Kinase><QOL><Qualifying><Quality of life><R-Series Research Projects><R01 Mechanism><R01 Program><RNA Expression><Regulation><Research><Research Grants><Research Personnel><Research Project Grants><Research Projects><Researchers><Resistance><Role of Tob in T-cell activation><STING agonists><Scientist><Signal Transduction><Signal Transduction Systems><Signaling><Source><T cell infiltration><T-Cell Activation Pathway><Talents><Testing><Therapeutic><Tissues><Transcription><Translating><Translational Research><Translational Science><Translations><Treatment Efficacy><Type I Phosphatidylinositol Kinase><Type III Phosphoinositide 3-Kinase><U.S. Males><US Men><US male><Universities><Visceral><Work><androgen independent prostate cancer><androgen indifferent prostate cancer><androgen insensitive prostate cancer><androgen resistance in prostate cancer><androgen resistant prostate cancer><anti-cancer research><anti-tumor response><antibody based therapies><antibody treatment><antibody-based therapeutics><antibody-based treatment><biological signal transduction><bone><c myc><c-myc Genes><cancer genetics><cancer microenvironment><cancer research><care for patients><care of patients><career><caring for patients><castration resistant CaP><castration resistant PCa><castration resistant prostate cancer><check point blockade><checkpoint blockade><cmyc><cohort><combination therapy><combined modality treatment><combined treatment><design><designing><determine efficacy><developmental><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><evaluate efficacy><examine efficacy><experience><experiment><experimental research><experimental study><experiments><hormone refractory prostate cancer><humanized monoclonal antibodies><immune check point blockade><immune checkpoint blockade><immune microenvironment><immune therapeutic approach><immune therapeutic interventions><immune therapeutic regimens><immune therapeutic strategy><immune therapy><immune-based therapies><immune-based treatments><immuno therapy><immunosuppressive microenvironment><immunosuppressive tumor microenvironment><improved><improved outcome><inhibitor><innovate><innovation><innovative><intervention efficacy><investigator-initiated trial><males in America><males in the U.S.><males in the US><males in the USA><males in the United States><member><men><men in America><men in the U.S.><men in the US><men in the USA><men in the United States><mortality><mouse model><multi-modal therapy><multi-modal treatment><murine model><mutated in multiple advanced cancers 1 protein><new approaches><new drug treatments><new drugs><new pharmacological therapeutic><new technology><new therapeutics><new therapy><next generation therapeutics><novel><novel approaches><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel strategies><novel strategy><novel technologies><novel therapeutics><novel therapy><pathway><patient oriented outcomes><patient population><pharmaceutical><phase I protocol><phosphatase and tensin homologue on chromosome ten><pre-IND consultation><pre-IND discussion><pre-IND meeting><pre-Investigational New Drug meeting><pre-clinical study><preclinical study><programmed cell death 1><programmed cell death protein 1><programmed death 1><programs><prostate cancer model><prostate cancer resistant to androgen><prostate tumor model><recruit><rejuvenating intervention><rejuvenation approach><rejuvenation strategies><rejuvenation therapy><rejuvenation treatment><resistant><safety study><sle2><success><systemic lupus erythematosus susceptibility 2><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment><therapeutic efficacy><therapeutic rejuvenation><therapy efficacy><translation><translation research><translational investigation><tumor><tumor immune microenvironment><tumor microenvironment><tumor-immune system interactions><v-myc Avian Myelocytomatosis Viral Oncogene Cellular Homolog>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

SUBHASH C. PANDEY

UNIVERSITY OF ILLINOIS AT CHICAGO, Chicago, IL

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,659,417
FY 2025

Project Title

Center for Alcohol Research in Epigenetics

Grant Number:

2P50AA022538-11

Activity Code:

P50

Mechanism:

Research Centers

Agency:

NIH

Start Date:

6/3/2025

End Date:

5/31/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Project Summary: Alcohol use disorder (AUD) can be characterized by a pattern of compulsive alcohol drinking and development of several withdrawal symptoms that promote relapse and maintenance of addiction. Long-term alcohol use causes molecular, structural, and functional changes in key brain regio...

Research Terms

<ATAC sequencing><ATAC-seq><ATACseq><Acceleration><Alcohol Chemical Class><Alcohol Drinking><Alcohol consumption><Alcohol dependence><Alcohol withdrawal syndrome><Alcohols><Ammon Horn><Amygdala><Amygdaloid Body><Amygdaloid Nucleus><Amygdaloid structure><Animal Model><Animal Models and Related Studies><Anxiety><Anxiety Disorders><Area><Assay for Transposase-Accessible Chromatin using sequencing><Autopsy><Behavioral><Body Tissues><Brain><Brain Nervous System><Brain region><CRISPR><CRISPR approach><CRISPR based approach><CRISPR method><CRISPR methodology><CRISPR technique><CRISPR technology><CRISPR tools><CRISPR-CAS-9><CRISPR-based method><CRISPR-based technique><CRISPR-based technology><CRISPR-based tool><CRISPR/CAS approach><CRISPR/Cas method><CRISPR/Cas system><CRISPR/Cas technology><CRISPR/Cas9><CRISPR/Cas9 technology><Cas nuclease technology><Cell Body><Cell Communication and Signaling><Cell Nucleus><Cell Signaling><Cells><Cholesterol><Chromatin><Chromatin Structure><Chronic><Clustered Regularly Interspaced Short Palindromic Repeats><Clustered Regularly Interspaced Short Palindromic Repeats approach><Clustered Regularly Interspaced Short Palindromic Repeats method><Clustered Regularly Interspaced Short Palindromic Repeats methodology><Clustered Regularly Interspaced Short Palindromic Repeats technique><Clustered Regularly Interspaced Short Palindromic Repeats technology><Cognition><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Common Rat Strains><Community Outreach><Cornu Ammonis><DNA Methylation><DNA Methyltransferase><DNA Modification Methylases><DNA Modification Methyltransferases><DNA mutation><DNA-Methyltransferases><Data><Data Analyses><Data Analysis><Development><Disturbance in cognition><Dnmt><Dorsal><Drug Therapy><Dysfunction><Electrophysiology><Electrophysiology (science)><Encephalon><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><EtOH drinking><EtOH use><Female><Functional disorder><Funding><Gene Action Regulation><Gene Expression><Gene Expression Regulation><Gene Regulation><Gene Regulation Process><Gene Transcription><General Population><General Public><Genes><Genetic Change><Genetic Transcription><Genetic defect><Genetic mutation><Genetic study><Genomics><HDAC><HDAC Proteins><HPA axis><Heterogeneity><High School Student><Hippocampus><Histone Acetylase><Histone Acetylation><Histone Deacetylase><Human><Hyperalgesia><Hyperalgesic Sensations><Impaired cognition><Intracellular Communication and Signaling><Investigation><Investigators><Knowledge><L-Lysine><Light><Link><Lysine><MD students><Maintenance><Major Depressive Disorder><Medial><Medical Students><Mental Depression><Methylation><Modeling><Modern Man><Modification Methylases><Molecular><Mutation><Nerve Cells><Nerve Transmitter Substances><Nerve Unit><Neural Cell><Neurocyte><Neuroimmune><Neurons><Neuropeptides><Neurophysiology / Electrophysiology><Neurosciences><Neurotransmitters><Nucleus><Pain><Painful><Panic><Panic Disorder><Pathogenesis><Pathway interactions><Pattern><Pharmacological Treatment><Pharmacotherapy><Phenotype><Photoradiation><Physiopathology><Population><Postdoc><Postdoctoral Fellow><Prefrontal Cortex><Progress Reports><Protein Family><Proteins><Public Health><R-Series Research Projects><R01 Mechanism><R01 Program><RNA Expression><RNA Seq><RNA sequencing><RNAseq><Rat><Rats Mammals><Rattus><Reader><Regulation><Relapse><Research><Research Associate><Research Grants><Research Personnel><Research Project Grants><Research Projects><Research Resources><Researchers><Resources><Rewards><Rodent Model><Scientist><Secondary School Student><Secondary Student><Signal Transduction><Signal Transduction Systems><Signaling><Signaling Molecule><Single-Nucleus Sequencing><Site-Specific DNA-methyltransferase><Specificity><Synapses><Synaptic><Tissues><Transcription><Translational Research><Translational Science><Validation><Ventral Tegmental Area><Visit><Vulnerable Populations><Withdrawal><Withdrawal Symptom><addiction><addictive disorder><alcohol abuse therapy><alcohol abuse treatment><alcohol addiction><alcohol dependency><alcohol dependent><alcohol exposed><alcohol exposure><alcohol ingestion><alcohol intake><alcohol product use><alcohol related research><alcohol research><alcohol treatment><alcohol use><alcohol use disorder><alcohol use prevention><alcohol withdrawal><alcoholic beverage consumption><alcoholic drink intake><amygdaloid nuclear complex><assay for transposase accessible chromatin followed by sequencing><assay for transposase accessible chromatin seq><assay for transposase accessible chromatin sequencing><assay for transposase-accessible chromatin with sequencing><behavior phenotype><behavioral phenotyping><biological signal transduction><brain circuitry><career><cell type><clinical depression><co-morbid><co-morbidity><cognitive dysfunction><cognitive loss><comorbidity><data interpretation><depression><deter alcohol use><developmental><drug discovery><drug intervention><drug treatment><druggable target><electrophysiological><entire genome><environment enrichment><environment enrichment for laboratory animals><environmental enrichment><environmental enrichment for laboratory animals><epigenetic drug><epigenetic modifying drugs><epigenetic regulation><epigenetically><epigenome><epigenomics><ethanol consumption><ethanol drinking><ethanol exposed><ethanol exposure><ethanol ingestion><ethanol intake><ethanol product use><ethanol research><ethanol use><ethanol use disorder><ethanol withdrawal><exposed to alcohol><exposed to ethanol><exposure to alcohol><exposure to ethanol><full genome><gene network><genome mutation><global gene expression><global transcription profile><high schoolers><higher education><hippocampal><histone H3 methyltransferase><histone acetyltransferase><histone methylase><histone methyltransferase><histone modification><human subject><hyperalgia><hypothalamic-pituitary-adrenal (HPA) axis><hypothalamic-pituitary-adrenal axis><hypothalmus-pituitary-adrenal axis><improved><inhibitor><insight><interdisciplinary approach><major depression><major depression disorder><male><medical school students><model of animal><multidisciplinary approach><necropsy><neuronal><neurotrophic factor><neurotrophin><neutrophin><new drug target><new druggable target><new pharmacotherapy target><new therapeutic target><new therapy target><next generation><novel><novel drug target><novel druggable target><novel pharmacotherapy target><novel therapeutic target><novel therapy target><outreach program><panic anxiety syndrome><pathophysiology><pathway><pharmaceutical intervention><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><post-doc><post-doctoral><post-doctoral trainee><postmortem><pre-clinical research><preclinical research><prevent alcohol use><recruit><research associates><response><sNuc-Seq><sex><shRNA><short hairpin RNA><single nucleus RNA-sequencing><single nucleus seq><single-nucleus RNA-seq><small hairpin RNA><small molecule><snRNA sequencing><snRNA-seq><spatial RNA sequencing><spatial gene expression analysis><spatial gene expression profiling><spatial resolved transcriptome sequencing><spatial transcriptome analysis><spatial transcriptome profiling><spatial transcriptome sequencing><spatial transcriptomics><spatially resolved transcriptomics><spatio transcriptomics><synapse><training opportunity><transcriptome><transcriptome sequencing><transcriptomic sequencing><transcriptomics><translation research><translational investigation><undergrad><undergraduate><undergraduate student><validations><ventral tegmentum><vulnerable group><vulnerable individual><vulnerable people><whole genome><withdrawal from alcohol><♀><♂>
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Kyle Edwin Orwig

MAGEE-WOMEN'S RES INST AND FOUNDATION, Pittsburgh, PA

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,644,034
FY 2025

Project Title

Genetics of Male Infertility: Accelerating the pace of discovery

Grant Number:

5P50HD096723-07

Activity Code:

P50

Mechanism:

Research Centers

Agency:

NIH

Start Date:

9/1/2019

End Date:

6/30/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Abstract: Overall Azoospermia impacts 1% of men globally, which translates to 645,000 men between the ages of 20 and 50 in the United States. It is estimated that genetic causes explain 50% of infertility. Improved knowledge about the genetic basis of infertility and associated overall health comorb...

Research Terms

<0-11 years old><2 year college><Academy><Acceleration><Address><Adoption><Affect><Age><American male><American man><American men><Benefits and Risks><Biological><Cancers><Cannot achieve a pregnancy><Cardiovascular Diseases><Cell Body><Cells><Child><Child Youth><Children (0-21)><Chimera><Chimera organism><Clinic><Clinical Treatment><Clinical genetics><Co-culture><Cocultivation><Coculture><Coculture Techniques><Collaborations><Communication><Communities><Complex thinking><Counseling><Couples><Critical Thinking><DNA Therapy><Data><Data Analytics><Data Set><Development><Diagnosis><Diagnostic><Differentiation in cell culture><Difficulty conceiving><Disease><Disorder><ES cell differentiation><ESC differentiation><Education><Education Module><Education and Outreach><Educational Module><Educational aspects><Emotional well being><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Evaluative Thinking><Family><Feels well><Female><Funding><Gametes><Gametogenesis><Gene Transfer Clinical><Gene variant><Generations><Genes><Genetic><Genetic Diversity><Genetic Intervention><Genetic Variation><Genetics-Mutagenesis><Genomic Testing><Germ Cells><Germ Lines><Germ-Line Cells><Health><High School Student><Human><In Vitro><In vitro cell differentiation><Individual><Infertility><Insertional Mutagenesis><Instruction and Outreach><International><Jobs><Knowledge><Laboratory Research><Lead><Learning Module><Life Expectancy><Link><Male Infertility><Malignant Neoplasms><Malignant Tumor><Medical><Medical Genetics><Meiosis><Mentors><Metabolic syndrome><Methods><Mice><Mice Mammals><Mission><Modeling><Modern Man><Murine><Mus><Mutagenesis><Mutagenesis Molecular Biology><Normal mental condition><Normal mental state><Normal psyche><Occupations><P50 Mechanism><P50 Program><Pathogenicity><Patients><Pb element><Phenotype><Primordial Germ Cell><Professional Positions><Program Description><Psychological Well Being><Reproduction><Reproductive Biology><Reproductive Cells><Reproductive Health><Reproductive Medicine><Research><Risk><Running><Science><Secondary School Student><Secondary Student><Sense of well-being><Sex Cell><Site><Specialized Center><Sperm stem cell><Structure of primordial sex cell><Students><Sum><Teaching Module><Technology><Teen><Teenagers><Testicles><Testis><Time><Training and Outreach><Translating><Translations><Transmission><Tutoring and Outreach><U.S. Males><US Men><US male><United States><Validation><Variant><Variation><Well in self><Youth><Youth 10-21><ages><allelic variant><assisted reproduction><biologic><candidate identification><cardiovascular disorder><career><chimeras><clinical development><clinical diagnostics><clinical intervention><clinical therapy><co-morbid><co-morbidity><college student><community college><comorbidity><cost><customized therapy><customized treatment><cytokine><data exchange><data transfer><data transmission><developmental><diagnostic development><diagnostic screening><differentiation in culture><differentiation in embryonic stem cells><differentiation in vitro><disease model><disorder model><embryonic precursor differentiation><embryonic stem cell differentiation><emotional wellbeing><emotional wellness><engineered progenitor cells><engineered stem cells><entire genome><epigenetically><exome sequencing><exome-seq><experience><experiment><experimental research><experimental study><experiments><fertility cessation><fertility loss><fetal><full genome><gene corrected><gene correction><gene repair therapy><gene therapy><gene-based therapy><gene-based treatment><gene-directed therapy><gene-targeted therapy><gene-targeted treatment><genetic linkage><genetic therapy><genetic variant><genome based testing><genome editing><genome sequencing><genome testing><genomic DNA testing><genomic based testing><genomic clinical testing><genomic correction><genomic editing><genomic profiling testing><genomic screening test><genomic therapy><genomic variant><heavy metal Pb><heavy metal lead><high school><high schoolers><idiopathic infertility><improved><in vitro cellular differentiation><individualized medicine><individualized patient treatment><individualized therapeutic strategy><individualized therapy><individualized treatment><induced pluripotent stem cells derived from patients><induced pluripotent stem cells from patients><infertile><infertile males><infertile men><infertility in men><initial cell><junior college><junior high><junior high school><kids><lab experience><lab training><laboratory experience><laboratory training><male><male factor infertility><males in America><males in the U.S.><males in the US><males in the USA><males in the United States><malignancy><medical diagnostic><meiotic><men><men facing infertility><men in America><men in the U.S.><men in the US><men in the USA><men in the United States><men with infertility><mental well-being><mental wellbeing><mental wellness><middle school><mouse model><murine model><neoplasm/cancer><patient derived human iPS><patient derived human iPSC><patient derived human induced pluripotent stem cell><patient derived iPS><patient derived iPSC><patient derived induced pluripotent cells><patient derived induced pluripotent stem cells><patient specific therapies><patient specific treatment><patient-derived pluripotent stem cells><personalization of treatment><personalized medicine><personalized therapy><personalized treatment><programs><psychological wellbeing><psychological wellness><reproductive><safety and feasibility><safety testing><screening><screenings><self wellness><sense of wellbeing><sertoli cell><sexual cell><sperm progenitor><spermatogonia cell><spermatogonia progenitor><spermatogonia stem cells><spermatogonial cell><spermatogonial progenitor><spermatogonial stem cells><tailored medical treatment><tailored therapy><tailored treatment><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment><teen years><teenage><testis sustentacular cell><translation><transmission process><trial regimen><trial treatment><two year college><under served community><underserved community><unexplained infertility><unique treatment><university student><validations><whole genome><youngster><youth age><♀><♂>
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JENNIE G NOLL

UNIVERSITY OF ROCHESTER, ROCHESTER, NY

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,619,405
FY 2025

Project Title

Translational Research that Adapts New Science FORMaltreatment prevention (TRANSFORM)

Grant Number:

5P50HD096698-08

Activity Code:

P50

Mechanism:

Research Centers

Agency:

NIH

Start Date:

9/13/2018

End Date:

8/31/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

OVERALL CORE Every year, millions of children in the United States suffer child abuse and neglect (USDHHS, 2022). Our CAPSTONE Center for Multidisciplinary Research in Child Abuse and Neglect (P50) Project renewal goals are to advance a national resource center for conducting innovative research, di...

Research Terms

<0-11 years old><Address><Causality><Child><Child Abuse and Neglect><Child Welfare><Child Youth><Childhood maltreatment><Children (0-21)><Communities><Development><Etiology><Evidence based program><Experimental Designs><Family><Focus Groups><Fostering><Foundations><Geography><Goals><History><Interdisciplinary Research><Interdisciplinary Study><International><Intervention><Intervention Studies><Investigators><Life Cycle><Life Cycle Stages><Measurement><Mental Health><Mental Hygiene><Methodology><Methods><Modeling><Multidisciplinary Collaboration><Multidisciplinary Research><NICHD><National Institute of Child Health and Human Development><Outcome><Pilot Projects><Policies><Policy Maker><Prevention><Psychological Health><Psychopathology><R-Series Research Projects><R01 Mechanism><R01 Program><Randomized, Controlled Trials><Recording of previous events><Research><Research Design><Research Grants><Research Methodology><Research Methods><Research Personnel><Research Project Grants><Research Projects><Research Resources><Researchers><Resources><Science><Scientist><Socialization><Solid><Stress><Study Type><Symptoms><System><Testing><Translational Research><Translational Science><United States><Universities><Work><Youth><Youth 10-21><abnormal psychology><adolescent welfare><analytical method><causation><child maltreatment><child well being><child wellbeing><clinical practice><community based participatory research><community engagement><community led research><community participatory research><community partnered participatory research><community partners><community-based partners><coping><developmental><disease causation><engagement with communities><evidence base><histories><improved><innovate><innovation><innovative><intergenerational><intervention research><interventional research><interventional study><interventions research><investigator training><kids><life course><longitudinal database><maltreatment><mistreatment><next generation><outreach><participatory action research><pilot study><prevent><preventing><programs><randomized control trial><research and methods><study design><translation research><translational investigation><youngster><youth age>
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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Sheree Lynn Toth

UNIVERSITY OF ROCHESTER, ROCHESTER, NY

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,619,405
FY 2025

Project Title

Translational Research that Adapts New Science FORMaltreatment prevention (TRANSFORM)

Grant Number:

5P50HD096698-08

Activity Code:

P50

Mechanism:

Research Centers

Agency:

NIH

Start Date:

9/13/2018

End Date:

8/31/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

OVERALL CORE Every year, millions of children in the United States suffer child abuse and neglect (USDHHS, 2022). Our CAPSTONE Center for Multidisciplinary Research in Child Abuse and Neglect (P50) Project renewal goals are to advance a national resource center for conducting innovative research, di...

Research Terms

<0-11 years old><Address><Causality><Child><Child Abuse and Neglect><Child Welfare><Child Youth><Childhood maltreatment><Children (0-21)><Communities><Development><Etiology><Evidence based program><Experimental Designs><Family><Focus Groups><Fostering><Foundations><Geography><Goals><History><Interdisciplinary Research><Interdisciplinary Study><International><Intervention><Intervention Studies><Investigators><Life Cycle><Life Cycle Stages><Measurement><Mental Health><Mental Hygiene><Methodology><Methods><Modeling><Multidisciplinary Collaboration><Multidisciplinary Research><NICHD><National Institute of Child Health and Human Development><Outcome><Pilot Projects><Policies><Policy Maker><Prevention><Psychological Health><Psychopathology><R-Series Research Projects><R01 Mechanism><R01 Program><Randomized, Controlled Trials><Recording of previous events><Research><Research Design><Research Grants><Research Methodology><Research Methods><Research Personnel><Research Project Grants><Research Projects><Research Resources><Researchers><Resources><Science><Scientist><Socialization><Solid><Stress><Study Type><Symptoms><System><Testing><Translational Research><Translational Science><United States><Universities><Work><Youth><Youth 10-21><abnormal psychology><adolescent welfare><analytical method><causation><child maltreatment><child well being><child wellbeing><clinical practice><community based participatory research><community engagement><community led research><community participatory research><community partnered participatory research><community partners><community-based partners><coping><developmental><disease causation><engagement with communities><evidence base><histories><improved><innovate><innovation><innovative><intergenerational><intervention research><interventional research><interventional study><interventions research><investigator training><kids><life course><longitudinal database><maltreatment><mistreatment><next generation><outreach><participatory action research><pilot study><prevent><preventing><programs><randomized control trial><research and methods><study design><translation research><translational investigation><youngster><youth age>
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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Paula Elaine Cohen

CORNELL UNIVERSITY, ITHACA, NY

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,614,188
FY 2025

Project Title

Spermatogenic gene regulation and infertility

Grant Number:

5P50HD104454-05

Activity Code:

P50

Mechanism:

Research Centers

Agency:

NIH

Start Date:

5/1/2021

End Date:

3/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

The Cornell Center for Reproductive Genomics (CRG) was founded in 2007 with the goal of leveraging state-of- the-art genomics technologies for understanding the biology of the mammalian germ cell. More specifically, our goal has been to understand the genetic, epigenetic, and epitranscriptomic basis...

Research Terms

<0-11 years old><3' Untranslated Regions><3'UTR><ATAC sequencing><ATAC-seq><ATACseq><Address><Affect><Alternate Splicing><Alternative RNA Splicing><Alternative Splicing><Aneuploid><Aneuploidy><Assay for Transposase-Accessible Chromatin using sequencing><Assisted Reproduction Technology><Assisted Reproductive Technology><Benchmarking><Best Practice Analysis><Biology><Bromodomain><Cannot achieve a pregnancy><Cell Body><Cells><Child><Child Youth><Children (0-21)><Chromatin><Chromatin Remodeling Complex><Chromatin Remodeling Factor><Clinical><Collaborations><Communities><Complex><Couples><Defect><Deposit><Deposition><Development><Difficulty conceiving><Ensure><Environment><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Event><Expression Signature><Faculty><Fecundability><Fecundity><Fertility><Fertilization><Foundations><Functional RNA><Gametes><Gene Action Regulation><Gene Expression><Gene Expression Profile><Gene Expression Regulation><Gene Regulation><Gene Regulation Process><Gene Transcription><Generations><Genes><Genetic><Genetic Transcription><Genome><Genomics><Germ Cells><Germ-Line Cells><Goals><Grant><Haploid><Haploidy><Head><High Throughput Assay><Histones><Human><Infertility><Institution><Life Cycle><Life Cycle Stages><Male Infertility><Meiosis><Mentorship><Messenger RNA><Methylation><Mice><Mice Mammals><Modern Man><Modification><Morphology><Murine><Mus><NGS Method><NGS system><New York><Non-Polyadenylated RNA><Noncoding RNA><Nontranslated RNA><Nuclear><P50 Mechanism><P50 Program><Participant><Pathogenicity><Patients><Pattern><Pennsylvania><Pilot Projects><Play><Polyadenylation><Population><Post-Transcriptional Control><Post-Transcriptional Regulation><Process><Production><Property><Protamines><Proteins><RNA><RNA Expression><RNA Gene Products><RNA Polyadenylation><RNA Seq><RNA metabolism><RNA sequencing><RNAseq><Regulation><Regulatory Pathway><Reproduction><Reproductive Biology><Reproductive Cells><Research><Research Resources><Resources><Ribonucleic Acid><Role><Rural><Schools><Scientist><Sex Cell><Site><Source><Specialized Center><Sperm><Sperm Count><Sperm Count Procedure><Sperm Motility><Sperm Numbers><Sperm stem cell><Spermatocytes><Spermatogenesis><Spermatogenic Cell><Spermatozoa><Spermiocytes><Spermiogenesis><Technology><Testicles><Testing><Testis><Time><Transcription><Transcriptional Control><Transcriptional Regulation><Translations><United States><Universities><Untranslated RNA><Variant><Variation><assay for transposase accessible chromatin followed by sequencing><assay for transposase accessible chromatin seq><assay for transposase accessible chromatin sequencing><assay for transposase-accessible chromatin with sequencing><assistive reproductive technology><benchmark><career><chromatin modifier><clinical significance><clinically significant><combinatorial><conference><convention><developmental><epigenetically><epigenomics><epitranscriptomics><fertility cessation><fertility loss><fertilizations><gene expression pattern><gene expression signature><genome profiling><genomic profiling><global gene expression><global transcription profile><high throughput screening><improved><indexing><infertile><infertile males><infertile men><infertility in men><initial cell><innovate><innovation><innovative><insight><interest><kids><life course><mRNA><mRNA Stability><mRNA Translation><male><male factor infertility><male fertility><male germ cells><meeting><meetings><meiotic><men><men facing infertility><men with infertility><mouse model><murine model><next gen sequencing><next generation sequencing><nextgen sequencing><noncoding><pilot study><post-transcriptional gene regulation><posttranscriptional><recruit><reproductive><role model><school district><sexual cell><social role><sperm cell><sperm function><sperm mobility><sperm morphology><sperm progenitor><sperm quality><spermatogonia cell><spermatogonia progenitor><spermatogonia stem cells><spermatogonial cell><spermatogonial progenitor><spermatogonial stem cells><summit><symposia><symposium><transcriptional profile><transcriptional signature><transcriptome><transcriptome sequencing><transcriptomic sequencing><transcriptomics><translation><translation strategy><translational approach><translational strategy><under served community><underserved community><youngster><zoosperm><♂>
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MICHAEL F MILES

VIRGINIA COMMONWEALTH UNIVERSITY, RICHMOND, VA

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,602,300
FY 2025

Project Title

Cross-species investigation of gene networks for ethanol-related behaviors

Grant Number:

2P50AA022537-11

Activity Code:

P50

Mechanism:

Research Centers

Agency:

NIH

Start Date:

8/5/2014

End Date:

5/31/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Project Summary – Overall Alcohol use disorders (AUDs) represent a major public health burden. Genetic risk factors contribute significantly to the susceptibility to develop AUDs and are likely to be a result of many variants that each contribute modestly to risk. Genetic studies in animal models a...

Research Terms

<Absolute ethanol><Acute><Address><Affect><Alcohol Chemical Class><Alcohol Drinking><Alcohol abuse><Alcohol consumption><Alcohols><Animal Model><Animal Models and Related Studies><Animals><Area><Behavior><Behavioral><Behavioral Model><Biological><Biological Function><Biological Process><Biology><Brain><Brain Nervous System><C elegans><C. elegans><C.elegans><Caenorhabditis elegans><Candidate Disease Gene><Candidate Gene><Causality><Cause of Death><Cessation of life><Communities><Data><Data Analyses><Data Analysis><Death><Development><Disease><Disorder><Dissection><Drosophila><Drosophila genus><ETOH><Effectiveness><Encephalon><Equation><EtOH abuse><EtOH drinking><EtOH use><Ethanol><Ethyl Alcohol><Etiology><Flies><Funding><GWA study><GWAS><Gene variant><Generalized Growth><Genes><Genetic><Genetic Risk><Genetic Screening><Genetic Vectors><Genetic predisposing factor><Genetic study><Genomic approach><Genomics><Grain Alcohol><Grant><Growth><Heavy Drinking><History><Human><Human Genetics><Human Genome><Individual><Intervention><Invertebrata><Invertebrates><Investigation><Investigators><Lead><Leadership><Left><Link><Methylcarbinol><Mice><Mice Mammals><Modeling><Modern Man><Molecular><Murine><Mus><NIAAA><National Institute on Alcohol Abuse and Alcoholism><Neural Pathways><Nucleotides><Organizational Goals><Organizational Objectives><Pb element><Phenotype><Pilot Projects><Population><Position><Positioning Attribute><Predisposition><Prevention><Public Health><R-Series Research Projects><R01 Mechanism><R01 Program><Recording of previous events><Research Grants><Research Personnel><Research Project Grants><Research Projects><Research Resources><Researchers><Resolution><Resources><Risk><Risk-associated variant><Sampling Studies><Statistical Methods><Structure><Sum><Susceptibility><Testing><Therapeutic><Therapeutic Agents><Tissue Growth><Translating><United States><Validation><Variant><Variation><Viral Vector><Work><alcohol behavior><alcohol co-abuse><alcohol induced behavior><alcohol ingestion><alcohol intake><alcohol problem><alcohol product use><alcohol related behavior><alcohol related research><alcohol research><alcohol response><alcohol risk><alcohol sensitivity><alcohol use><alcohol use disorder><alcoholic beverage consumption><alcoholic drink intake><allelic variant><analysis pipeline><base><bases><behavior response><behavioral response><biologic><candidate validation><causation><data interpretation><data sharing><design><designing><developmental><discover genes><disease causation><drink heavily><ethanol abuse><ethanol behavior><ethanol consumption><ethanol drinking><ethanol induced behavior><ethanol ingestion><ethanol intake><ethanol product use><ethanol related behavior><ethanol research><ethanol response><ethanol sensitivity><ethanol use><ethanol use disorder><excessive alcohol consumption><excessive alcohol ingestion><excessive alcohol intake><excessive drinking><excessive ethanol ingestion><exome sequencing><exome-seq><extreme drinking><fly><fruit fly><gene discovery><gene network><genetic approach><genetic risk factor><genetic strategy><genetic variant><genome scale><genome wide association><genome wide association scan><genome wide association study><genome-wide><genomewide><genomewide association scan><genomewide association study><genomic effort><genomic strategy><genomic variant><hazardous alcohol use><heavy alcohol use><heavy metal Pb><heavy metal lead><histories><human whole genome><improved><inherited factor><innovate><innovation><innovative><interest><model of animal><model organism><multiomics><multiple omics><new diagnostics><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation diagnostics><next generation therapeutics><novel><novel diagnostics><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><ontogeny><overexpress><overexpression><panomics><pilot study><problem alcohol use><problem drinking><problematic alcohol consumption><problematic alcohol use><programs><resolutions><response to alcohol><response to ethanol><risk allele><risk gene><risk genotype><risk loci><risk locus><risk variant><sensitivity to alcohol><sensitivity to ethanol><statistic methods><substance misuse><tool><trait><transfection vector><translational study><validations><whole genome association analysis><whole genome association study>
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Elizabeth A Stewart

MAYO CLINIC ROCHESTER, ROCHESTER, MN

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,516,960
FY 2025

Project Title

COllaboration for EQuity in Uterine Leiomyomas

Grant Number:

5P50HD115283-02

Activity Code:

P50

Mechanism:

Research Centers

Agency:

NIH

Start Date:

6/19/2024

End Date:

4/30/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY - OVERALL COEQUaL, the COllaboration for EQuity in Uterine Leiomyomas, builds on longstanding collaborations among women with uterine fibroids (UF) and multidisciplinary researchers at Mayo Clinic, Fibroid Foundation, University of Mississippi Medical Center and University of Florida...

Research Terms

<Adoption><Advocacy><Affect><African American><African American Females><African American Women><African American group><African American individual><African American people><African American population><African Americans><Afro American><Afroamerican><Agreement><Anemia><Antihormone Agents><Articulation><Awareness><Behavioral Sciences><Black><Black race><Bleeding><Caring><Clinic><Clinical><Collaborations><Communication><Conceptions><Data><Decision Making><Decrease disparity><Disease><Disorder><Disparities><Disparity><Dysfunction><Early Intervention><Education><Education and Outreach><Educational aspects><Electronic Health Record><Equity><Ethics><FSH-Releasing Hormone><Fibroid><Fibroid Neoplasm><Fibroid Tumor><Fibroid Uterus><Fibromyoma><Florida><Foundations><Functional disorder><Goals><Gonadoliberin><Gonadorelinum><Gonadotropin Hormone Releasing Hormone><Gonadotropin-Releasing Hormone><Health Care Providers><Health Care Systems><Health Disparities Research><Health Personnel><Health disparities related research><Hemorrhage><Hormone Antagonists><Hysterectomy><Individual><Instruction and Outreach><Insurance><Insurance Carriers><Insurers><International><Internships><Intervention><Investigators><LH-FSH Releasing Hormone><LH-Releasing Hormone><LHFSH Releasing Hormone><Leiomyomatous Neoplasm><Leiomyomatous Tumor><Logistics><Lower disparity><Luliberin><Luteinizing Hormone-Releasing Factor><Medicaid><Medical center><Medicine><Mentors><Mississippi><Modality><Modeling><Modernization><Myometrial><NCMHD><NIMHD><National Center on Minority Health and Health Disparities><National Institute of Minority Health and Health Disparities><National Institute on Minority Health and Health Disparities><Neoplasms><Newsletter><Operative Procedures><Operative Surgical Procedures><Oral><Outcome><Ovary><P50 Mechanism><P50 Program><Pain><Painful><Patient advocacy><Patients><Physiopathology><Pilot Projects><Policies><Precision care><Process><Provider><Public Health><Pulsti><Recombinant Gonadorelin><Research><Research Personnel><Researchers><Science><Source><Specialized Center><Students><Surgical><Surgical Interventions><Surgical Procedure><Symptoms><Technology><Therapeutic><Therapeutic GRH><Training><Training and Outreach><Tutoring and Outreach><Universities><Uterine Body Fibroid><Uterine Body Leiomyoma><Uterine Corpus Fibroid><Uterine Corpus Leiomyoma><Uterine Fibroids><Uterine Fibroma><Uterine Leiomyoma><Uterus><Uterus Fibroma><Woman><Work><advocacy organizations><age group><barrier to care><barrier to health care><barrier to treatment><behavioral and social science><blood loss><cardiometabolic><cardiometabolism><clinical care><college><collegiate><community partnership><corpus uteri fibroid><corpus uteri leiomyoma><design><designing><disparities affecting females><disparities affecting women><disparities among females><disparities among women><disparities facing women><disparities impacting women><disparities in females><disparities in women><disparity elimination><disparity in health><disparity reduction><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><eliminate disparities><eliminating disparities><empowerment><ethical><evidence base><experience><female disparities><follicle stimulating hormone-releasing factor><gonadotropin releasing factor><health care personnel><health care worker><health disparities science><health disparity><health equity><health provider><health workforce><hormone inhibitor><improved><improved outcome><individualized care><individualized patient care><innovate><innovation><innovative><intern><medical personnel><mitigate disparity><mortality><multidisciplinary><neoplasia><neoplastic growth><next generation><obstacle to care><obstacle to health care><pathophysiology><personalized care><personalized patient care><pilot study><podcast><pressure><programs><psychologic><psychological><racial diversity><racially diverse><reduce disparity><reduction in disparity><reproductive><risk prediction algorithm><risk prediction model><social science research><success><surgery><synergism><tool><treatment provider><uterine artery embolization><uterus leiomyoma><womb><women's disparities>
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Carlos Fernando Valenzuela

UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR, ALBUQUERQUE, NM

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,453,116
FY 2025

Project Title

C0-Overall: Fetal Ethanol-induced behavior deficits: Mechanisms, diagnosis and Intervention

Grant Number:

5P50AA022534-12

Activity Code:

P50

Mechanism:

Research Centers

Agency:

NIH

Start Date:

8/5/2014

End Date:

6/30/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

NMARC is a NIAAA-designated Specialized Alcohol Research P50 Center comprised of teams of preclinical and clinical scientists with a history of collaborative research interactions, whose expertise and contributions have synergized the center’s research environment and is facilitating progress toward...

Research Terms

<0-11 years old><ARHGEF5><ARHGEF5 gene><Acceleration><Achievement><Achievement Attainment><Acquired brain injury><Address><Advisory Committees><Affect><Alcohol Chemical Class><Alcohols><Area><Award><Behavioral><Biochemical><Biological Markers><Brain Injuries><Child><Child Youth><Children (0-21)><Cities><Clinical><Clinical Investigator><Clinical Research><Clinical Study><Collaborations><Communication><Community Outreach><Development><Diagnosis><Drug Therapy><Education><Educational aspects><Ensure><Environment><FASD><Faculty><Fetal Alcohol Exposure><Fetal Alcohol Spectrum Disorder><Fetal ETOH Exposure><Fetal Ethanol Exposure><Fetal alcohol effects><Fetus><Foundations><GEF5><Goals><Grant><Health Sciences><History><In Utero Alcohol Exposure><In Utero ETOH Exposure><In Utero Ethanol Exposure><Individual><International><Intervention><Investigation><Investigators><Knowledge><Leadership><Life><Mentors><Methods><NIAAA><National Institute on Alcohol Abuse and Alcoholism><New Mexico><P60><Patients><Pharmacological Treatment><Pharmacotherapy><Phase><Philosophy><Physiologic><Physiological><Pilot Projects><Prenatal Alcohol Exposure><Prenatal ETOH Exposure><Prenatal Ethanol Exposure><Procedures><Production><Recording of previous events><Research><Research Activity><Research Personnel><Research Resources><Research Support><Researchers><Resources><Risk><Scientist><Series><TIM1><Task Forces><Training><Training Programs><Universities><Work><advisory team><alcohol behavior><alcohol consumption during pregnancy><alcohol during pregnancy><alcohol induced behavior><alcohol intake during pregnancy><alcohol related behavior><alcohol related research><alcohol research><alcohol-exposed pregnancy><bio-markers><biobehavior><biobehavioral><biologic marker><biomarker><brain damage><brain-injured><clinical investigation><conference><convention><data management><determine efficacy><developmental><diagnostic biomarker><diagnostic marker><drinking alcohol during pregnancy><drug intervention><drug treatment><effective intervention><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><ethanol behavior><ethanol consumption during pregnancy><ethanol induced behavior><ethanol related behavior><ethanol research><evaluate efficacy><examine efficacy><exposed to alcohol prenatally><faculty mentor><fetal><gestation ETOH exposure><gestation alcohol exposure><gestation ethanol exposure><gestational ethanol exposure><graduate student><histories><human subject><kids><lab experience><lab training><laboratory experience><laboratory training><meeting><meetings><neurobehavioral><neurobiological mechanism><novel><offspring><pharmaceutical intervention><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><pilot study><pre-clinical><pre-doc><pre-doctoral><preclinical><pregnancy ETOH exposure><pregnancy alcohol exposure><pregnancy ethanol exposure><prenatal><prenatal alcohol consumption><prenatal alcohol effect><prenatal alcohol use><prenatal drinking><prenatal intervention><prenatally alcohol exposed><prenatally exposed to alcohol><prognostic><programs><recruit><summit><symposia><symposium><synergism><tool><translational investigator><translational researcher><translational scientist><unborn><undergrad><undergraduate><undergraduate student><web page><webpage><youngster>
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Abraham A. Palmer

UNIVERSITY OF CALIFORNIA, SAN DIEGO, LA JOLLA, CA

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,387,925
FY 2025

Project Title

Center for Genetics, Genomics, and Epigenetics of Substance Use Disorders in Outbred Rats

Grant Number:

5P30DA060810-02

Activity Code:

P30

Mechanism:

Research Centers

Agency:

NIH

Start Date:

9/1/2024

End Date:

5/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Project Summary (Overall) The goal of this P30 application is to support the community of scientists who use outbred heterogeneous stock (HS) rats to understand the genetic basis of individual differences in vulnerability to substance use disorders (SUDs). Although this is a new grant, one of its m...

Research Terms

<0-4 weeks old><Address><Alcohol Chemical Class><Alcohols><Alleles><Allelomorphs><Attention><Behavior><Behavioral><Breeding><California><Cell Body><Cells><Cessation of life><Chromosomes><Common Rat Strains><Communities><Complex><Criminal Justice><DNA Recombination><Data><Data Bases><Databases><Death><Diacetylmorphine><Diamorphine><Dihydrohydroxycodeinone><Education><Educational aspects><Electrophysiology><Electrophysiology (science)><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Europe><FAIR data><FAIR guiding principles><FAIR principles><Findable, Accessible, Interoperable and Re-usable><Findable, Accessible, Interoperable, and Reusable><Funding><GWA study><GWAS><Gene Expression><Generations><Genes><Genetic><Genetic Predisposition><Genetic Predisposition to Disease><Genetic Recombination><Genetic Susceptibility><Genetic Technics><Genetic Techniques><Genetic propensity><Genetic study><Genomics><Genotype><Goals><Grant><Health Care Costs><Health Costs><Heroin><Human><Impulsivity><Inbred Strains Rats><Individual Differences><Inherited Predisposition><Inherited Susceptibility><Investigators><Learning><Machine Learning><Maps><Measures><Mental disorders><Mental health disorders><Methodology><Mice><Mice Mammals><Modern Man><Murine><Mus><NIDA><NIDDK><National Institute of Diabetes and Digestive and Kidney Diseases><National Institute of Drug Abuse><National Institute on Drug Abuse><Neurophysiology / Electrophysiology><Newborn Infant><Newborns><Nicotine><Oxycodeinon><Oxycodone><Oxycodone SR><Oxycontin><Pathway interactions><Phenotype><Pilot Projects><Population><Productivity><Psychiatric Disease><Psychiatric Disorder><QTL><Quantitative Genetics><Quantitative Trait Loci><Rat><Rats Mammals><Rattus><Recombination><Research Personnel><Researchers><Roxicodone><Scientist><Services><Slice><Substance Use Disorder><Techniques><Time><Universities><addiction><addictive disorder><cocaine self-administration><comparator group><comparison group><cost><data base><data management><data sharing><design><designing><distributed data><effective therapy><effective treatment><electrophysiological><epigenetically><epigenomics><genetic approach><genetic etiology><genetic mechanism of disease><genetic strategy><genetic vulnerability><genetically predisposed><genome wide association><genome wide association scan><genome wide association study><genomewide association scan><genomewide association study><global gene expression><global transcription profile><high school><innovate><innovation><innovative><machine based learning><mental illness><multidisciplinary><newborn child><newborn children><novel><pathway><pilot study><premature><prematurity><psychiatric illness><psychological disorder><rat genome><self-administer cocaine><substance use and disorder><therapeutic target><trait><transcriptome><transcriptomics><undergrad><undergraduate><undergraduate student><virtual><web site><website><whole genome association analysis><whole genome association study>
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STEVEN A. KAUTZ

MEDICAL UNIVERSITY OF SOUTH CAROLINA, CHARLESTON, SC

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,330,433
FY 2025

Project Title

Center for Advancing Precision Neural Circuit-Based Rehabilitation (Neuro-PRECISE)

Grant Number:

1P50HD118628-01

Activity Code:

P50

Mechanism:

Research Centers

Agency:

NIH

Start Date:

9/15/2025

End Date:

8/31/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

COMMUNITY ENGAGEMENT & OUTREACH CORE – PROJECT SUMMARY / ABSTRACT The goal of the Community Engagement & Outreach (CEO) Core is to maximize stakeholder engagement for the Neuro-PRECISE Center, including researchers, clinicians, students, the public, and, importantly, consumers of rehabilitation serv...

Research Terms

<Academy><Address><Advisory Committees><Advocate><Archives><Award><Brain><Brain Nervous System><CNS Injury><CNS plasticity><COBRE><Catalogs><Center of Biomedical Research Excellence><Centers of Research Excellence><Clinical><Clinical Research><Clinical Study><Cognitive><Collaborations><Communication><Communities><Community Outreach><Compensation><Complex><Data><Development><Development and Research><Disabled Persons><Disabled Population><Disease><Disorder><Educational workshop><Encephalon><Ensure><Equipment Design><Foundations><Functional MRI><Functional Magnetic Resonance Imaging><Funding><Goals><Handicapped><Image><Individual><Institution><Instrumental Learning><International><Intervention><Investigators><Joints><Lead><Leadership><Lived experience><Lived experiences><Medical><Medical Rehabilitation><Medical center><Medicine><Methodology><Methods><NICHD><NIGMS><NIH><National Institute of Child Health and Human Development><National Institute of General Medical Sciences><National Institutes of Health><Nervous System><Neuro rehabilitation><Neurologic Body System><Neurologic Organ System><Neuronal Plasticity><Neurorehabilitation><Operant Conditioning><Pb element><Peer Review><People with Disabilities><Persons><Persons with Disabilities><Physiologic><Physiological><Pilot Projects><Process><R & D><R&D><R-Series Research Projects><R01 Mechanism><R01 Program><Rehabilitation><Rehabilitation therapy><Reporting><Research><Research Activity><Research Grants><Research Infrastructure><Research Personnel><Research Project Grants><Research Projects><Research Resources><Researchers><Resource Sharing><Resources><Science><Scientist><Services><Sight><South Carolina><Spinal><Students><Sum><Task Forces><Technology><Therapeutic><Training><United States National Institutes of Health><Universities><Vision><Voice><Work><Workshop><advisory team><care partner><caregiving partner><catalog><central nervous system injury><central nervous system plasticity><community engagement><community partners><community-based partners><conference><convention><design><designing><developmental><disability><disabled individual><disabled people><engagement with communities><experience><fMRI><functional restoration><heavy metal Pb><heavy metal lead><imaging><imaging biomarker><imaging marker><imaging-based biological marker><imaging-based biomarker><imaging-based marker><improved><individuals with disabilities><injured CNS><innovate><innovation><innovative><instrumental conditioning><neural><neural circuit><neural circuitry><neural control><neural plasticity><neural regulation><neurocircuitry><neurological rehab><neurological rehabilitation><neuromodulation><neuromodulatory><neuroplastic><neuroplasticity><neuroregulation><neurorehab><neurorehabilitative><next generation><non-invasive brain stimulation><outreach><outreach program><pilot study><programs><psychosocial><rehab research><rehab therapy><rehabilitation research><rehabilitation service><rehabilitative><rehabilitative therapy><research and development><research facility><restoration><restore function><restore functionality><restore lost function><success><summit><symposia><symposium><synaptic circuit><synaptic circuitry><tech development><technology development><theories><therapeutic outcome><therapy outcome><tool><visual function><web site><webinar><website>
View Full Project Details on NIH Reporter
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Jane E Roberts

UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA, COLUMBIA, SC

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,314,024
FY 2025

Project Title

Translation of the FMR1 Premutation Phenotypes Across the Lifespan

Grant Number:

1P50HD118708-01

Activity Code:

P50

Mechanism:

Research Centers

Agency:

NIH

Start Date:

9/10/2025

End Date:

8/31/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Carriers of the FMR1 premutation allele (FXpm) are at risk to develop Fragile X-associated Tremor/Ataxia Syndrome (FXTAS) and Fragile X-associated Neuropsychiatric Disorders (FXAND). Despite significant impacts including functional limitations, reduced quality of life, poor health, and even reduced ...

Research Terms

<5 year old><5 years of age><Address><Affect><Age><Age Years><Alleles><Allelomorphs><Animals><Biological><CGG repeat><Cognitive Manifestations><Cognitive Symptoms><Collaborations><Communication><Data><Development><Escalante syndrome><FMR-1 Protein><FMR1 Premutation><FMR1 Protein><FMR1 gene><FMRP><FMRP protein><FRAXA><FXTAS><Family><Female><Fragile X><Fragile X Mental Retardation 1 Gene><Fragile X Mental Retardation Protein><Fragile X Syndrome><Fragile X premutation-associated tremor ataxia syndrome><Genetic><Genetic Diversity><Genetic Variation><Goals><Health><Hearing><Hearing Loss><Human><Hypoacuses><Hypoacusis><Individual><Intervention><Investigation><Investigators><Knowledge><Language><Length><Life Expectancy><Martin-Bell Syndrome><Martin-Bell-Renpenning syndrome><Messenger RNA><Modern Man><Molecular><Molecular Genetics><NIH><National Institutes of Health><Neurobehavioral Manifestations><Neurobehavioral Signs and Symptoms><Pathway interactions><Phenotype><Predicting Risk><QOL><Quality of life><Renpenning syndrome 2><Research><Research Personnel><Researchers><Risk><Risk Factors><Sampling><Scientist><Strategic Planning><Symptoms><Translating><Translations><Tremor/Ataxia Syndrome><United States National Institutes of Health><Variant><Variation><Woman><Work><X-linked mental deficiency-megalotestes syndrome><X-linked mental retardation with fragile X syndrome><X-linked mental retardation-fragile site 1 syndrome><age 5 years><ages><auditory processing><autism-fragile X (AFRAX) syndrome><biologic><clinical phenotype><clinical risk><developmental><dysfunctional hearing><five year old><five years of age><forecasting risk><fra(X) syndrome><fra(X)(28) syndrome><fra(X)(q27) syndrome><fra(X)(q27-28) syndrome><fragile X FMR1 protein><fragile X associated tremor ataxia syndrome><fragile X mental retardation 1><fragile X mental retardation-1 protein><fragile X-associated tremor/ataxia syndrome><fragile X-mental retardation syndrome><fragile Xq syndrome><fragile site mental retardation 1><genetic analysis><hearing challenged><hearing defect><hearing deficient><hearing deficit><hearing difficulty><hearing dysfunction><hearing impairment><life span><lifespan><mRNA><macro-orchidism-marker X (MOMX) syndrome><macro-orchidism-marker X syndrome><mar(X) syndrome><marker X syndrome><mental retardation-macroorchidism syndrome><motor symptom><neurobehavioral symptom><neuropsychiatric disease><neuropsychiatric disorder><novel><pathway><predict risk><predict risks><predicted risk><predicted risks><predicting risks><predictive risk><predicts risk><psychiatric symptom><recruit><risk prediction><risk predictions><sex><social communication><social relationships><synergism><translation><translation strategy><translational approach><translational strategy><♀>
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Anthony W Ferrante

COLUMBIA UNIVERSITY HEALTH SCIENCES, NEW YORK, NY

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,221,081
FY 2025

Project Title

New York Obesity Research Center

Grant Number:

5P30DK026687-45

Activity Code:

P30

Mechanism:

Research Centers

Agency:

NIH

Start Date:

12/1/1996

End Date:

3/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

The New York Obesity Nutrition Research Center (NYNORC) has as its primary aim to convene and support - by its Core Services, Pilot & Feasibility and Enrichment programs - funded investigators at Columbia University and the Albert Einstein College of Medicine studying obesity. The themes for this Ce...

Research Terms

<0-4 weeks old><Achievement><Achievement Attainment><Advisory Committees><Ally><Animals><Approaches to prevention><Area><Award><Back><Basic Research><Basic Science><Behavior><Behavioral><Bile Acids><Biology><Biomedical Research><Body Composition><Causality><Cell Therapy><Center Core Grants><Clinical><Clinical Evaluation><Clinical Investigator><Clinical Testing><Collaborations><Communities><Core Facility><Creativeness><DNA Molecular Biology><Defense Mechanisms><Development><Diabetes Mellitus><Direct Costs><Disease><Disorder><Dorsum><Dysfunction><Eating><Elements><Environment><Etiology><Fatty Liver><Food Intake><Food Intake Regulation><Fostering><Foundations><Functional disorder><Funding><Funding Agency><Funding Source><Genes><Goals><Grant><History><Human><Individual><Institution><Interdisciplinary Research><Interdisciplinary Study><Investigation><Investigators><Laboratories><Liver Steatosis><Manuscripts><Mediation><Medical center><Medicine><Mentors><Metabolic><Modern Man><Molecular Biology><Molecular Genetics><Monitor><Multidisciplinary Collaboration><Multidisciplinary Research><NIDDK><NIH><National Institute of Diabetes and Digestive and Kidney Diseases><National Institutes of Health><Negotiating><Negotiation><Nerve Cells><Nerve Unit><Neural Cell><Neurobiology><Neurocyte><Neurons><Neurosciences><New York><Newborn Infant><Newborns><Nutrient><Nutrition><Nutrition Research><Nutritional><Nutritional Study><Obesity><P30 Award><P30 Grant><P30 Mechanism><P30 Program><P50 Mechanism><P50 Program><Pathogenesis><Pathology><Patients><Peer Review><Pharmaceutical Agent><Pharmaceuticals><Pharmacologic Substance><Pharmacological Substance><Phenotype><Physiologic><Physiological><Physiology><Physiopathology><Pilot Projects><Preventative strategy><Prevention><Prevention approach><Prevention strategy><Preventive strategy><Productivity><Progenitor Cells><Publishing><R-Series Research Projects><R01 Mechanism><R01 Program><Recording of previous events><Regulation><Research><Research Grants><Research Personnel><Research Project Grants><Research Projects><Research Resources><Researchers><Resources><Risk-associated variant><Role><Science><Scientist><Series><Services><Specialized Center><Task Forces><Techniques><Training><Translational Research><Translational Research Enterprise><Translational Science><United States National Institutes of Health><Universities><Weight><Weight Gain><Weight Increase><adiposity><advisory team><application in practice><base><bases><body weight gain><body weight increase><causation><cell based intervention><cell mediated intervention><cell mediated therapies><cell-based therapeutic><cell-based therapy><cellular therapeutic><cellular therapy><child adiposity><child obesity><childhood adiposity><childhood obesity><clinical care><clinical test><co-morbid><co-morbidity><college><collegiate><comorbidity><corpulence><creativity><design><designing><developmental><diabetes><disease causation><dosage><hepatic steatosis><hepatosteatosis><histories><innovate><innovation><innovative><insight><instrument><interdisciplinary collaboration><interest><investigator training><knowledge base><member><neurobiological><neuronal><newborn child><newborn children><next generation><novel><nutritious><obese children><obesity development><obesity during childhood><obesity in children><obesity intervention><obesity therapy><obesity treatment><pathophysiology><pediatric obesity><pharmaceutical><pilot study><practical application><preference><programs><psychological defense mechanism><research clinical testing><risk allele><risk gene><risk genotype><risk loci><risk locus><risk variant><skills><social role><stem cells><sugar><tool><transdisciplinary collaboration><translation research><translation research enterprise><translational investigation><translational research program><treatment strategy><weights><wt gain>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

DYMPNA GALLAGHER

COLUMBIA UNIVERSITY HEALTH SCIENCES, NEW YORK, NY

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,221,081
FY 2025

Project Title

New York Obesity Research Center

Grant Number:

5P30DK026687-45

Activity Code:

P30

Mechanism:

Research Centers

Agency:

NIH

Start Date:

12/1/1996

End Date:

3/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

The New York Obesity Nutrition Research Center (NYNORC) has as its primary aim to convene and support - by its Core Services, Pilot & Feasibility and Enrichment programs - funded investigators at Columbia University and the Albert Einstein College of Medicine studying obesity. The themes for this Ce...

Research Terms

<0-4 weeks old><Achievement><Achievement Attainment><Advisory Committees><Ally><Animals><Approaches to prevention><Area><Award><Back><Basic Research><Basic Science><Behavior><Behavioral><Bile Acids><Biology><Biomedical Research><Body Composition><Causality><Cell Therapy><Center Core Grants><Clinical><Clinical Evaluation><Clinical Investigator><Clinical Testing><Collaborations><Communities><Core Facility><Creativeness><DNA Molecular Biology><Defense Mechanisms><Development><Diabetes Mellitus><Direct Costs><Disease><Disorder><Dorsum><Dysfunction><Eating><Elements><Environment><Etiology><Fatty Liver><Food Intake><Food Intake Regulation><Fostering><Foundations><Functional disorder><Funding><Funding Agency><Funding Source><Genes><Goals><Grant><History><Human><Individual><Institution><Interdisciplinary Research><Interdisciplinary Study><Investigation><Investigators><Laboratories><Liver Steatosis><Manuscripts><Mediation><Medical center><Medicine><Mentors><Metabolic><Modern Man><Molecular Biology><Molecular Genetics><Monitor><Multidisciplinary Collaboration><Multidisciplinary Research><NIDDK><NIH><National Institute of Diabetes and Digestive and Kidney Diseases><National Institutes of Health><Negotiating><Negotiation><Nerve Cells><Nerve Unit><Neural Cell><Neurobiology><Neurocyte><Neurons><Neurosciences><New York><Newborn Infant><Newborns><Nutrient><Nutrition><Nutrition Research><Nutritional><Nutritional Study><Obesity><P30 Award><P30 Grant><P30 Mechanism><P30 Program><P50 Mechanism><P50 Program><Pathogenesis><Pathology><Patients><Peer Review><Pharmaceutical Agent><Pharmaceuticals><Pharmacologic Substance><Pharmacological Substance><Phenotype><Physiologic><Physiological><Physiology><Physiopathology><Pilot Projects><Preventative strategy><Prevention><Prevention approach><Prevention strategy><Preventive strategy><Productivity><Progenitor Cells><Publishing><R-Series Research Projects><R01 Mechanism><R01 Program><Recording of previous events><Regulation><Research><Research Grants><Research Personnel><Research Project Grants><Research Projects><Research Resources><Researchers><Resources><Risk-associated variant><Role><Science><Scientist><Series><Services><Specialized Center><Task Forces><Techniques><Training><Translational Research><Translational Research Enterprise><Translational Science><United States National Institutes of Health><Universities><Weight><Weight Gain><Weight Increase><adiposity><advisory team><application in practice><base><bases><body weight gain><body weight increase><causation><cell based intervention><cell mediated intervention><cell mediated therapies><cell-based therapeutic><cell-based therapy><cellular therapeutic><cellular therapy><child adiposity><child obesity><childhood adiposity><childhood obesity><clinical care><clinical test><co-morbid><co-morbidity><college><collegiate><comorbidity><corpulence><creativity><design><designing><developmental><diabetes><disease causation><dosage><hepatic steatosis><hepatosteatosis><histories><innovate><innovation><innovative><insight><instrument><interdisciplinary collaboration><interest><investigator training><knowledge base><member><neurobiological><neuronal><newborn child><newborn children><next generation><novel><nutritious><obese children><obesity development><obesity during childhood><obesity in children><obesity intervention><obesity therapy><obesity treatment><pathophysiology><pediatric obesity><pharmaceutical><pilot study><practical application><preference><programs><psychological defense mechanism><research clinical testing><risk allele><risk gene><risk genotype><risk loci><risk locus><risk variant><skills><social role><stem cells><sugar><tool><transdisciplinary collaboration><translation research><translation research enterprise><translational investigation><translational research program><treatment strategy><weights><wt gain>
View Full Project Details on NIH Reporter
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S. Ali Fatemi

HUGO W. MOSER RES INST KENNEDY KRIEGER, BALTIMORE, MD

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,184,001
FY 2025

Project Title

Intellectual and Developmental Disabilities Research Centers

Grant Number:

3P50HD103538-05S1

Activity Code:

P50

Mechanism:

Research Centers

Agency:

NIH

Start Date:

4/1/2025

End Date:

5/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY/ABSTRACT This P50 award will continue to support the Intellectual and Developmental Disabilities Research Center (IDDRC), which has been central to the scientific enterprise at the Kennedy Krieger Institute (KKI) and Johns Hopkins University (JHU) for over 30 years—supporting investi...

Research Terms

<ASD><Addison disease-cerebral sclerosis syndrome><Addison disease-spastic paraplegia syndrome><Addison-Schilder syndrome><Address><Adrenoleukodystrophy><Advocacy><Attention><Autism><Autistic Disorder><Award><Basic Research><Basic Science><Brain><Brain Nervous System><Bronze Schilder disease><COVID crisis><COVID epidemic><COVID pandemic><COVID-19 crisis><COVID-19 epidemic><COVID-19 era><COVID-19 global health crisis><COVID-19 global pandemic><COVID-19 health crisis><COVID-19 pandemic><COVID-19 period><COVID-19 public health crisis><COVID-19 years><Causality><Center for Translational Science Activities><Child Development Disorders><Childhood><Circadian Dysregulation><Clinic><Collaborations><Communities><Complex><Data Analyses><Data Analysis><Data Collection><Dedications><Detection><Development><Developmental Disabilities><Disability research><Disability study><EXTMR><Early Infantile Autism><Early identification><Education><Educational aspects><Encephalon><Ensure><Etiology><Extramural><Extramural Activities><Face><Fanconi-Prader syndrome><Funding><Genomics><Goals><Human><IDDRC><IDDRP><Individual><Infantile Autism><Infrastructure><Institution><Intellectual and Developmental Disabilities Research Centers><Intellectual disability><Intellectual functioning disability><Intellectual limitation><Interdisciplinary Research><Interdisciplinary Study><Intervention><Investigation><Investigators><Kanner's Syndrome><Knowledge><Leadership><Link><MRDD Research Center><MRDDRC><Machine Learning><Maryland><Measures><Mental Retardation and Developmental Disabilities Research Centers><Mentorship><MicroRNAs><Modern Man><Molecular><Multidisciplinary Collaboration><Multidisciplinary Research><NICHD><National Institute of Child Health and Human Development><Natural History><Neurodevelopmental Disability><Outcome Measure><Patient Recruitments><Patients><Policies><Prevalence><Prevention><Public Health><Public Health Schools><Public Policy><Questionnaires><R-Series Research Projects><R01 Mechanism><R01 Program><Research><Research Design><Research Grants><Research Personnel><Research Priority><Research Project Grants><Research Projects><Research on disabilities><Researchers><Resource Sharing><Risk Factors><Role><SARS-CoV-2 epidemic><SARS-CoV-2 global health crisis><SARS-CoV-2 global pandemic><SARS-CoV-2 pandemic><SARS-coronavirus-2 epidemic><SARS-coronavirus-2 pandemic><Schilder-Addison Complex><Schools><Scientific Inquiry><Screening procedure><Services><Severe Acute Respiratory Syndrome CoV 2 epidemic><Severe Acute Respiratory Syndrome CoV 2 pandemic><Severe acute respiratory syndrome coronavirus 2 epidemic><Severe acute respiratory syndrome coronavirus 2 pandemic><Shapes><Siemerling-Creutzfeldt disease><Siemerling-Creutzfeldt syndrome><Site><Sleep><Sleep Disorders><Structure><Study Type><Study on disabilities><Time><Training><Translational Research><Translational Science><Translations><Universities><X-Linked Adrenoleukodystrophy><actigraph><actigraphy><adrenocortical atrophy-cerebral sclerosis syndrome><adrenoleukomyeloneuropathy><analytical method><autism attributes><autism indicator><autism spectral disorder><autism spectrum disorder><autism spectrum disorder features><autism spectrum disorder indicator><autism spectrum disorder symptoms><autism symptomology><autism symptoms><autism-like symptoms><autism-related attributes><autistic children><autistic features><autistic spectrum disorder><autistic symptoms><autistic traits><autistic-like symptoms><behavior phenotype><behavioral phenotyping><biomarker identification><career><causation><children on the autism spectrum><children with ASD><children with autism><children with autism spectrum disorder><circadian abnormality><circadian disruption><circadian disturbance><circadian dysfunction><circadian impairment><clinical care><clinical practice><clinical translation><clinically translatable><co-morbid><co-morbidity><comorbidity><coronavirus disease 2019 crisis><coronavirus disease 2019 epidemic><coronavirus disease 2019 global health crisis><coronavirus disease 2019 global pandemic><coronavirus disease 2019 health crisis><coronavirus disease 2019 pandemic><coronavirus disease 2019 public health crisis><coronavirus disease crisis><coronavirus disease epidemic><coronavirus disease pandemic><coronavirus disease-19 global pandemic><coronavirus disease-19 pandemic><data interpretation><developmental><developmental disease><developmental disorder><disease causation><early screening><executive control><executive function><experience><faces><facial><identification of biomarkers><identification of new biomarkers><improved><improved outcome><intellectual and developmental disability><inter-institutional><knowledge translation><limited intellectual functioning><machine based learning><marker identification><measurable outcome><melanodermic leukodystrophy><miRNA><multidisciplinary><neural imaging><neuro-imaging><neurobehavioral><neuroimaging><neurological imaging><novel><outcome measurement><participant recruitment><pediatric><potential biological marker><potential biomarker><programs><screening tools><severe acute respiratory syndrome coronavirus 2 global health crisis><severe acute respiratory syndrome coronavirus 2 global pandemic><sleep behavior><sleep diseases><sleep dysfunction><sleep habit><sleep illness><sleep problem><sleep/wake behavior><social role><study design><translation><translation research><translational investigation><translational research center><translational sciences center>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Bradley L Schlaggar

HUGO W. MOSER RES INST KENNEDY KRIEGER, BALTIMORE, MD

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,184,001
FY 2025

Project Title

Intellectual and Developmental Disabilities Research Centers

Grant Number:

3P50HD103538-05S1

Activity Code:

P50

Mechanism:

Research Centers

Agency:

NIH

Start Date:

4/1/2025

End Date:

5/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY/ABSTRACT This P50 award will continue to support the Intellectual and Developmental Disabilities Research Center (IDDRC), which has been central to the scientific enterprise at the Kennedy Krieger Institute (KKI) and Johns Hopkins University (JHU) for over 30 years—supporting investi...

Research Terms

<ASD><Addison disease-cerebral sclerosis syndrome><Addison disease-spastic paraplegia syndrome><Addison-Schilder syndrome><Address><Adrenoleukodystrophy><Advocacy><Attention><Autism><Autistic Disorder><Award><Basic Research><Basic Science><Brain><Brain Nervous System><Bronze Schilder disease><COVID crisis><COVID epidemic><COVID pandemic><COVID-19 crisis><COVID-19 epidemic><COVID-19 era><COVID-19 global health crisis><COVID-19 global pandemic><COVID-19 health crisis><COVID-19 pandemic><COVID-19 period><COVID-19 public health crisis><COVID-19 years><Causality><Center for Translational Science Activities><Child Development Disorders><Childhood><Circadian Dysregulation><Clinic><Collaborations><Communities><Complex><Data Analyses><Data Analysis><Data Collection><Dedications><Detection><Development><Developmental Disabilities><Disability research><Disability study><EXTMR><Early Infantile Autism><Early identification><Education><Educational aspects><Encephalon><Ensure><Etiology><Extramural><Extramural Activities><Face><Fanconi-Prader syndrome><Funding><Genomics><Goals><Human><IDDRC><IDDRP><Individual><Infantile Autism><Infrastructure><Institution><Intellectual and Developmental Disabilities Research Centers><Intellectual disability><Intellectual functioning disability><Intellectual limitation><Interdisciplinary Research><Interdisciplinary Study><Intervention><Investigation><Investigators><Kanner's Syndrome><Knowledge><Leadership><Link><MRDD Research Center><MRDDRC><Machine Learning><Maryland><Measures><Mental Retardation and Developmental Disabilities Research Centers><Mentorship><MicroRNAs><Modern Man><Molecular><Multidisciplinary Collaboration><Multidisciplinary Research><NICHD><National Institute of Child Health and Human Development><Natural History><Neurodevelopmental Disability><Outcome Measure><Patient Recruitments><Patients><Policies><Prevalence><Prevention><Public Health><Public Health Schools><Public Policy><Questionnaires><R-Series Research Projects><R01 Mechanism><R01 Program><Research><Research Design><Research Grants><Research Personnel><Research Priority><Research Project Grants><Research Projects><Research on disabilities><Researchers><Resource Sharing><Risk Factors><Role><SARS-CoV-2 epidemic><SARS-CoV-2 global health crisis><SARS-CoV-2 global pandemic><SARS-CoV-2 pandemic><SARS-coronavirus-2 epidemic><SARS-coronavirus-2 pandemic><Schilder-Addison Complex><Schools><Scientific Inquiry><Screening procedure><Services><Severe Acute Respiratory Syndrome CoV 2 epidemic><Severe Acute Respiratory Syndrome CoV 2 pandemic><Severe acute respiratory syndrome coronavirus 2 epidemic><Severe acute respiratory syndrome coronavirus 2 pandemic><Shapes><Siemerling-Creutzfeldt disease><Siemerling-Creutzfeldt syndrome><Site><Sleep><Sleep Disorders><Structure><Study Type><Study on disabilities><Time><Training><Translational Research><Translational Science><Translations><Universities><X-Linked Adrenoleukodystrophy><actigraph><actigraphy><adrenocortical atrophy-cerebral sclerosis syndrome><adrenoleukomyeloneuropathy><analytical method><autism attributes><autism indicator><autism spectral disorder><autism spectrum disorder><autism spectrum disorder features><autism spectrum disorder indicator><autism spectrum disorder symptoms><autism symptomology><autism symptoms><autism-like symptoms><autism-related attributes><autistic children><autistic features><autistic spectrum disorder><autistic symptoms><autistic traits><autistic-like symptoms><behavior phenotype><behavioral phenotyping><biomarker identification><career><causation><children on the autism spectrum><children with ASD><children with autism><children with autism spectrum disorder><circadian abnormality><circadian disruption><circadian disturbance><circadian dysfunction><circadian impairment><clinical care><clinical practice><clinical translation><clinically translatable><co-morbid><co-morbidity><comorbidity><coronavirus disease 2019 crisis><coronavirus disease 2019 epidemic><coronavirus disease 2019 global health crisis><coronavirus disease 2019 global pandemic><coronavirus disease 2019 health crisis><coronavirus disease 2019 pandemic><coronavirus disease 2019 public health crisis><coronavirus disease crisis><coronavirus disease epidemic><coronavirus disease pandemic><coronavirus disease-19 global pandemic><coronavirus disease-19 pandemic><data interpretation><developmental><developmental disease><developmental disorder><disease causation><early screening><executive control><executive function><experience><faces><facial><identification of biomarkers><identification of new biomarkers><improved><improved outcome><intellectual and developmental disability><inter-institutional><knowledge translation><limited intellectual functioning><machine based learning><marker identification><measurable outcome><melanodermic leukodystrophy><miRNA><multidisciplinary><neural imaging><neuro-imaging><neurobehavioral><neuroimaging><neurological imaging><novel><outcome measurement><participant recruitment><pediatric><potential biological marker><potential biomarker><programs><screening tools><severe acute respiratory syndrome coronavirus 2 global health crisis><severe acute respiratory syndrome coronavirus 2 global pandemic><sleep behavior><sleep diseases><sleep dysfunction><sleep habit><sleep illness><sleep problem><sleep/wake behavior><social role><study design><translation><translation research><translational investigation><translational research center><translational sciences center>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

JOSEPH D DOUGHERTY

WASHINGTON UNIVERSITY, SAINT LOUIS, MO

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,164,521
FY 2025

Project Title

WASHINGTON UNIVERSITY INTELLECTUAL AND DEVELOPMENTAL DISABILITIES RESEARCH CENTER

Grant Number:

3P50HD103525-05S2

Activity Code:

P50

Mechanism:

Research Centers

Agency:

NIH

Start Date:

6/1/2025

End Date:

5/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Overall Project Abstract For the third cycle of the Intellectual and Developmental Disabilities Research Center at Washington University, we propose a next phase in a comprehensive approach to understanding, ameliorating, and/or preventing neurodevelopmental disability through translational scientif...

Research Terms

<0-11 years old><ASD><Active Follow-up><Affect><Animal Model><Animal Models and Related Studies><Autism><Autistic Disorder><Behavior><Behavioral><Biocompatible Materials><Bioinformatics><Biologic Models><Biological Markers><Biological Models><Biomaterials><Brain><Brain Nervous System><Brain imaging><Caliber><Calibration><Causality><Cell Body><Cell Line><Cell model><CellLine><Cells><Cellular model><Child><Child Development Disorders><Child Youth><Children (0-21)><Clinical><Clinical Trials><Collection><Communities><Core Facility><Data><Data Set><Dedications><Derivation><Derivation procedure><Development><Developmental Disabilities><Disability research><Disability study><Disease><Disorder><Disparate><Down Syndrome><Dysfunction><EXTMR><Early Infantile Autism><Electronic Health Record><Encephalon><Enrollment><Equipment and supply inventories><Etiology><Extramural><Extramural Activities><Faculty><Familial disease><Family><Functional disorder><Funding><Gene Copy Number><Gene Dosage><Gene variant><Generations><Genes><Genetic><Genomics><Goals><Human><IDDRC><IDDRP><Image><Individual><Infant><Infantile Autism><Institution><Intellectual and Developmental Disabilities Research Centers><Intellectual disability><Intellectual functioning disability><Intellectual limitation><Interruption><Intervention><Inventory><Investigation><Investigators><Kanner's Syndrome><Knowledge><Langdon Down syndrome><Longitudinal Studies><MRDD Research Center><MRDDRC><Mental Retardation and Developmental Disabilities Research Centers><Methods><Model System><Modern Man><Molecular><Mongolism><Mothers><NIH><National Institutes of Health><Natural History><Neurodevelopmental Disability><Neurosciences><P50 Mechanism><P50 Program><Pathogenesis><Pathway interactions><Patients><Phase><Phenotype><Physiopathology><Population><Preventative intervention><Prevention><Productivity><QOL><Qualifying><Quality of life><R-Series Research Projects><R01 Mechanism><R01 Program><Registries><Research><Research Grants><Research Infrastructure><Research Personnel><Research Project Grants><Research Projects><Research Resources><Research on disabilities><Researchers><Resources><Risk><Rodent Model><Science><Scientist><Site><Specialized Center><Specific qualifier value><Specified><Standardization><Strains Cell Lines><Structure><Study on disabilities><Synapses><Synaptic><Syndrome><Therapeutic><Translating><Translational Research><Translational Science><Translations><Trisomy 21><United States National Institutes of Health><Universities><Variant><Variation><Washington><active followup><allelic variant><autism spectral disorder><autism spectrum disorder><autistic spectrum disorder><behavior phenotype><behavioral phenotyping><bio-markers><biologic marker><biological material><biomarker><brain visualization><causation><chromosome 21 trisomy><chromosome 21 trisomy syndrome><clinical translation><clinically translatable><cognitive neuroscience><cohort><congenital acromicria syndrome><cultured cell line><developmental><discover genes><disease causation><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><enroll><familial disorder><follow up><follow-up><followed up><followup><functional genomics><gene discovery><genetic variant><genomic variant><imaging><imaging study><intellectual and developmental disability><intervention for prevention><kids><limited intellectual functioning><long-term study><longitudinal outcome studies><low-frequency mutation><medical college><medical schools><model of animal><morbus Down><multiomics><multiple omics><neural><neural imaging><neuro-imaging><neuroimaging><neurological imaging><new drug target><new drug treatments><new druggable target><new drugs><new pharmacological therapeutic><new pharmacotherapy target><new therapeutic target><new therapeutics><new therapy><new therapy target><next generation therapeutics><novel><novel drug target><novel drug treatments><novel druggable target><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel pharmacotherapy target><novel therapeutic target><novel therapeutics><novel therapy><novel therapy target><panomics><pathophysiology><pathway><patient population><premature><prematurity><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><programs><prospective><pseudohypertrophic progressive muscular dystrophy><psychosocial><rare allele><rare mutation><rare variant><school of medicine><success><synapse><synergism><translation><translation research><translational investigation><trisomy 21 syndrome><work group><working group><youngster>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Christina Gurnett

WASHINGTON UNIVERSITY, SAINT LOUIS, MO

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,164,521
FY 2025

Project Title

WASHINGTON UNIVERSITY INTELLECTUAL AND DEVELOPMENTAL DISABILITIES RESEARCH CENTER

Grant Number:

3P50HD103525-05S2

Activity Code:

P50

Mechanism:

Research Centers

Agency:

NIH

Start Date:

6/1/2025

End Date:

5/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Overall Project Abstract For the third cycle of the Intellectual and Developmental Disabilities Research Center at Washington University, we propose a next phase in a comprehensive approach to understanding, ameliorating, and/or preventing neurodevelopmental disability through translational scientif...

Research Terms

<0-11 years old><ASD><Active Follow-up><Affect><Animal Model><Animal Models and Related Studies><Autism><Autistic Disorder><Behavior><Behavioral><Biocompatible Materials><Bioinformatics><Biologic Models><Biological Markers><Biological Models><Biomaterials><Brain><Brain Nervous System><Brain imaging><Caliber><Calibration><Causality><Cell Body><Cell Line><Cell model><CellLine><Cells><Cellular model><Child><Child Development Disorders><Child Youth><Children (0-21)><Clinical><Clinical Trials><Collection><Communities><Core Facility><Data><Data Set><Dedications><Derivation><Derivation procedure><Development><Developmental Disabilities><Disability research><Disability study><Disease><Disorder><Disparate><Down Syndrome><Dysfunction><EXTMR><Early Infantile Autism><Electronic Health Record><Encephalon><Enrollment><Equipment and supply inventories><Etiology><Extramural><Extramural Activities><Faculty><Familial disease><Family><Functional disorder><Funding><Gene Copy Number><Gene Dosage><Gene variant><Generations><Genes><Genetic><Genomics><Goals><Human><IDDRC><IDDRP><Image><Individual><Infant><Infantile Autism><Institution><Intellectual and Developmental Disabilities Research Centers><Intellectual disability><Intellectual functioning disability><Intellectual limitation><Interruption><Intervention><Inventory><Investigation><Investigators><Kanner's Syndrome><Knowledge><Langdon Down syndrome><Longitudinal Studies><MRDD Research Center><MRDDRC><Mental Retardation and Developmental Disabilities Research Centers><Methods><Model System><Modern Man><Molecular><Mongolism><Mothers><NIH><National Institutes of Health><Natural History><Neurodevelopmental Disability><Neurosciences><P50 Mechanism><P50 Program><Pathogenesis><Pathway interactions><Patients><Phase><Phenotype><Physiopathology><Population><Preventative intervention><Prevention><Productivity><QOL><Qualifying><Quality of life><R-Series Research Projects><R01 Mechanism><R01 Program><Registries><Research><Research Grants><Research Infrastructure><Research Personnel><Research Project Grants><Research Projects><Research Resources><Research on disabilities><Researchers><Resources><Risk><Rodent Model><Science><Scientist><Site><Specialized Center><Specific qualifier value><Specified><Standardization><Strains Cell Lines><Structure><Study on disabilities><Synapses><Synaptic><Syndrome><Therapeutic><Translating><Translational Research><Translational Science><Translations><Trisomy 21><United States National Institutes of Health><Universities><Variant><Variation><Washington><active followup><allelic variant><autism spectral disorder><autism spectrum disorder><autistic spectrum disorder><behavior phenotype><behavioral phenotyping><bio-markers><biologic marker><biological material><biomarker><brain visualization><causation><chromosome 21 trisomy><chromosome 21 trisomy syndrome><clinical translation><clinically translatable><cognitive neuroscience><cohort><congenital acromicria syndrome><cultured cell line><developmental><discover genes><disease causation><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><enroll><familial disorder><follow up><follow-up><followed up><followup><functional genomics><gene discovery><genetic variant><genomic variant><imaging><imaging study><intellectual and developmental disability><intervention for prevention><kids><limited intellectual functioning><long-term study><longitudinal outcome studies><low-frequency mutation><medical college><medical schools><model of animal><morbus Down><multiomics><multiple omics><neural><neural imaging><neuro-imaging><neuroimaging><neurological imaging><new drug target><new drug treatments><new druggable target><new drugs><new pharmacological therapeutic><new pharmacotherapy target><new therapeutic target><new therapeutics><new therapy><new therapy target><next generation therapeutics><novel><novel drug target><novel drug treatments><novel druggable target><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel pharmacotherapy target><novel therapeutic target><novel therapeutics><novel therapy><novel therapy target><panomics><pathophysiology><pathway><patient population><premature><prematurity><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><programs><prospective><pseudohypertrophic progressive muscular dystrophy><psychosocial><rare allele><rare mutation><rare variant><school of medicine><success><synapse><synergism><translation><translation research><translational investigation><trisomy 21 syndrome><work group><working group><youngster>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

James O Hill

UNIVERSITY OF ALABAMA AT BIRMINGHAM, BIRMINGHAM, AL

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,113,750
FY 2025

Project Title

UAB Nutrition Obesity Research Center (NORC)

Grant Number:

5P30DK056336-24

Activity Code:

P30

Mechanism:

Research Centers

Agency:

NIH

Start Date:

6/1/2000

End Date:

5/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

UAB NORC PROGRAM SUMMARY/ABSTRACT We request funding to continue and expand on the outstanding success achieved by UAB's Nutrition Obesity Research Center (NORC) in its first four funding cycles and particularly during the past 4+ years. Inaugurated with NIH funding in 2000, our NORC fosters multidi...

Research Terms

<Address><Alabama><Animal Model><Animal Models and Related Studies><Applied Research><Applied Science><Area><Award><Basic Research><Basic Science><Behavioral Sciences><Body Weight decreased><Chronic Disease><Chronic Illness><Clinic><Clinical Research><Clinical Study><Collaborations><Communities><Country><Data Analyses><Data Analysis><Deep South><Dietary Intervention><Disabled Persons><Disabled Population><Education><Educational aspects><Educational workshop><Ensure><Environment><Exercise><Faculty><Fostering><Funding><Funding Opportunities><Future><Generalized Growth><Grant><Growth><Handicapped><High School Student><Infrastructure><Institution><Intermediary Metabolism><Investigators><Knowledge><Laboratories><Leadership><Maintenance><Metabolic><Metabolic Processes><Metabolism><NIH><Names><National Institutes of Health><Nutrition><Nutrition Interventions><Nutrition Research><Nutritional Interventions><Nutritional Science><Nutritional Study><Obesity><Paper><Participant><Peer Review><People with Disabilities><Personalized medical approach><Persons with Disabilities><Population><Productivity><Publishing><R-Series Research Projects><R01 Mechanism><R01 Program><Research><Research Design><Research Grants><Research Personnel><Research Project Grants><Research Projects><Researchers><Role><Scientist><Secondary School Student><Secondary Student><Series><Services><Study Type><Tissue Growth><Training><Training Programs><Translating><Translational Research><Translational Science><United States National Institutes of Health><Weight Loss><Weight Reduction><Work><Workshop><adiposity><base><bases><body weight loss><chronic disorder><clinical center><complex data><conference><convention><corpulence><data interpretation><diet intervention><disabled individual><disabled people><high schoolers><individualized approach><individuals with disabilities><interdisciplinary collaboration><life style intervention><lifestyle intervention><member><mindfulness><model of animal><multidisciplinary><name><named><naming><next generation><nutrition science><ontogeny><personalized approach><precision approach><precision nutrition><programs><prospective><recruit><social role><study design><success><summit><symposia><symposium><tailored approach><transdisciplinary collaboration><translation research><translational investigation><webinar><wt-loss>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Stephen T Higgins

UNIVERSITY OF VERMONT & ST AGRIC COLLEGE, BURLINGTON, VT

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,113,044
FY 2025

Project Title

Vermont Center on Behavior and Health

Grant Number:

5P30GM149331-03

Activity Code:

P30

Mechanism:

Research Centers

Agency:

NIH

Start Date:

8/1/2023

End Date:

7/31/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY Overall Plan The overarching goal of this application for a Phase 3 Center of Biomedical Research Excellence (COBRE) award is to firmly establish the Vermont Center on Behavior and Health (VCBH) at the University of Vermont (UVM) as a sustainable center of research excellence. This m...

Research Terms

<Advisory Committees><Applications Grants><Area><Award><Behavior><COBRE><Center of Biomedical Research Excellence><Centers of Research Excellence><Cessation of life><Chronic Disease><Chronic Illness><Clinical><Clinical Research><Clinical Study><Collaborations><Complex><Data><Death><Drug Therapy><Education><Educational aspects><Environment><Faculty><Fostering><Foundations><Funding><Funding Opportunities><Generalized Growth><Goals><Grant><Grant Proposals><Growth><HRSA><Health><Health Promotion><Health Resources and Services Administration><Individual><Industry><Institution><Interdisciplinary Research><Interdisciplinary Study><International><Intervention><Investigators><Journals><Knowledge><Learning><Life Style><Lifestyle><Magazine><Medical><Mentors><Multidisciplinary Collaboration><Multidisciplinary Research><NIH><National Institutes of Health><Nebraska><Neurobiology><Obesity><Pattern><Peer Review><Periodicals><Personal Behavior><Personal Conduct><Pharmacological Treatment><Pharmacotherapy><Phase><Pilot Projects><Policies><Position><Positioning Attribute><Preventive Medicine><Publications><Regimen><Research><Research Personnel><Researchers><Risk><Risk Behaviors><Risky Behavior><Role><Rural><Salutogenesis><Schedule><Science><Scientific Advances and Accomplishments><Scientific Publication><Scientist><Series><Structure><Substance abuse problem><System><Task Forces><Tissue Growth><Tobacco><Training><United States Health Resources and Services Administration><United States National Institutes of Health><Universities><Vermont><Vulnerable Populations><abuse of substances><addiction><addictive disorder><adiposity><advisory team><at risk behavior><behavior change><behavioral economics><behavioral health><brain research><career><chronic disorder><clinical care><college><collegiate><conference><contingency management><convention><corpulence><cost effective><disease risk><disorder risk><drug intervention><drug treatment><early-career faculty><evidence base><full professor><improved><innovate><innovation><innovative><lack of physical activity><lectures><member><multidisciplinary><neurobiological><next generation><ontogeny><periodic><periodical><pharmaceutical intervention><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><physical inactivity><pilot study><premature><prematurity><preventative medicine><programs><promoting health><scientific accomplishments><scientific advances><senior faculty><social role><sound><substance abuse><substance misuse><success><summit><symposia><symposium><vulnerable group><vulnerable individual><vulnerable people><work group><working group>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

SOPHIE MOLHOLM

ALBERT EINSTEIN COLLEGE OF MEDICINE, BRONX, NY

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,000,000
FY 2025

Project Title

SUPPORT FOR THE ROSE F KENNEDY IDDRC P50

Grant Number:

5P50HD105352-05

Activity Code:

P50

Mechanism:

Research Centers

Agency:

NIH

Start Date:

7/23/2021

End Date:

5/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY/ABSTRACT (OVERALL) The overarching purpose of the Rose F. Kennedy Intellectual and Developmental Disabilities Research Center (RFK IDDRC) is to improve the lives of children with intellectual and developmental disabilities (IDDs). Fifty- plus years of distinguished progress in basic,...

Research Terms

<0-11 years old><22q11 Chromosomal Microdeletion Syndrome><22q11 Deletion Syndrome><22q11.2 deletion syndrome><22q11.2DS><22q11DS><ASD><Advocate><Affect><Animal Behavior><Animals><Autism><Autistic Disorder><Autosomal dominant Opitz G/BBB syndrome><Basic Research><Basic Science><Beuren syndrome><Biological><Biology><Bourneville Disease><Bourneville Phakomatosis><Bourneville syndrome><Bourneville-Brissaud disease><Bourneville-Pringle syndrome><Cayler cardiofacial syndrome><Cerebroatrophic Hyperammonemia><Charge><Child><Child Youth><Children (0-21)><Children's Hospital><Chromosome 22q11.2 deletion syndrome><Clinic><Clinical><Clinical Research><Clinical Study><Collaborations><Communities><Community Outreach><Coupled><DNA mutation><Dedications><Di George syndrome><DiGeorge Syndrome><DiGeorge anomaly><DiGeorge sequence><Diagnosis><Disability research><Disability study><Disease><Disorder><Disorder of neurometabolic regulation><Disorder of neurometabolism regulation><Early Diagnosis><Early Infantile Autism><Educational workshop><Elfin Facies Syndrome><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Epiloia><Evaluation><Faculty><Faculty Recruitment><Family><Fanconi Schlesinger syndrome><Fanconi-Schlesinger syndrome><Fortification><Fostering><Funding><Ganglia><Gene Transcription><Genes><Genetic Change><Genetic Transcription><Genetic defect><Genetic mutation><Genomics><Goals><Grant><Head><Hospitals><Human><Human Resources><IDDRC><IDDRP><Image><Infant><Infantile Autism><Infantile spasms><Institution><Intellectual and Developmental Disabilities Research Centers><Intellectual disability><Intellectual functioning disability><Intellectual limitation><Intermediary Metabolism><Investigators><Kanner's Syndrome><L-Lysine><Laboratory Research><Leadership><Lightning Attacks><Link><Lysine><MRDD Research Center><MRDDRC><Manpower><Medical><Medical center><Medicine><Mental Retardation and Developmental Disabilities Research Centers><Metabolic Processes><Metabolism><Mission><Modern Man><Monitor><Multiple Neurofibromas><Mutation><NICHD><National Institute of Child Health and Human Development><Neonatal Screening><Nerve Cells><Nerve Unit><Neural Cell><Neural Ganglion><Neurocyte><Neurodevelopmental Disorder><Neurofibromatoses><Neurofibromatosis><Neurofibromatosis Syndrome><Neurological Development Disorder><Neurons><Newborn Infant Screening><Newsletter><On-Line Systems><Online Systems><Outcome><Participant><Pathogenesis><Pathway interactions><Patient Care><Patient Care Delivery><Patients><Pediatric Hospitals><Phenotype><Postdoc><Postdoctoral Fellow><Pringle disease><Quality Control><R-Series Research Projects><R01 Mechanism><R01 Program><RNA Expression><Recruitment Activity><Rehabilitation Centers><Research><Research Associate><Research Grants><Research Personnel><Research Project Grants><Research Projects><Research on disabilities><Researchers><Rett Disorder><Rett Syndrome><Role><Science><Scientist><Sedlackova syndrome><Services><Shprintzen syndrome><Solid><Structure><Students><Study on disabilities><Talents><Technology><Time><Training><Training Programs><Transcription><Translating><Translational Research><Translational Science><Tuberous Sclerosis><Universities><Visualization><West Syndrome><Williams Barratt syndrome><Williams Contiguous Gene Syndrome><Williams Syndrome><Williams-Barratt syndrome><Williams-Beuren Syndrome><Workshop><X-linked infantile spasms><active recruitment><adenoma sebaceum><animal tissue><arm><autism spectral disorder><autism spectrum disorder><autistic spectrum disorder><biologic><brain cell><care for patients><care of patients><caring for patients><cell engineering><cell imaging><cellular engineering><cellular imaging><cerebral sclerosis><clinical care><clinical phenotype><clinical training><clinical translation><clinically translatable><college><collegiate><conference><conotruncal anomaly face syndrome><convention><cost effectiveness><design><designing><developmental disease><developmental disorder><early detection><eclampsia nutans><elfin-facies hypercalcemia syndrome><epigenetically><epiploia><facilities for imaging><familial third and fourth pharyngeal pouch syndrome><flexion spasm><forging><genome mutation><greeting spasms><hereditary multiple system hamartomatosis><human tissue><hypercalcemia-peculiar facies-supravalvular aortic stenosis syndrome><hypercalcemia/Williams-Beuren syndrome><idiopathic hypercalcemia-supravalvular aortic stenosis syndrome><imaging><imaging center><imaging facilities><imaging-related facilities><improved><infantile salaam><infantile spasms with mental retardation><infantile spasms-hypsarrhythmia-mental retardation syndrome><innovate><innovation><innovative><insight><intellectual and developmental disability><jackknife spasm><kids><limited intellectual functioning><member><mental retardation-typical facies-aortic stenosis syndrome><multi-modality><multidisciplinary><multimodality><neurinomatosis centralis><neurodevelopmental disease><neurogenomics><neuromatosis universalis><neurometabolic disease><neurometabolic disorder><neurometabolism disease><neurometabolism disorder><neuronal><neurospongioblastosis diffusa><newborn screening><next generation><novel><online computer><operation><operations><outreach><outreach program><pathway><personnel><phacomatosis><pharyngeal pouch syndrome><post-doc><post-doctoral><post-doctoral trainee><precision medicine><precision-based medicine><prevent><preventing><programs><recruit teachers><rehabilitative center><research associates><research study><sclerosis tuberosa><screening program><social role><spongioblastosis circumscripta><summit><symposia><symposium><teacher recruitment><third and fourth pharyngeal pouch syndrome><thymic and parathyroid agenesis syndrome><tool><translation research><translational investigation><tuberose sclerosis><tuberous sclerosis complex><velo-cardio-facial syndrome><velocardiofacial syndrome><velofacial hypoplasia><web based><youngster>
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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Steven Upshaw Walkley

ALBERT EINSTEIN COLLEGE OF MEDICINE, BRONX, NY

Good lead · 68/100
Likely hiring
Large award
Active award
Team-scale grant
$1,000,000
FY 2025

Project Title

SUPPORT FOR THE ROSE F KENNEDY IDDRC P50

Grant Number:

5P50HD105352-05

Activity Code:

P50

Mechanism:

Research Centers

Agency:

NIH

Start Date:

7/23/2021

End Date:

5/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY/ABSTRACT (OVERALL) The overarching purpose of the Rose F. Kennedy Intellectual and Developmental Disabilities Research Center (RFK IDDRC) is to improve the lives of children with intellectual and developmental disabilities (IDDs). Fifty- plus years of distinguished progress in basic,...

Research Terms

<0-11 years old><22q11 Chromosomal Microdeletion Syndrome><22q11 Deletion Syndrome><22q11.2 deletion syndrome><22q11.2DS><22q11DS><ASD><Advocate><Affect><Animal Behavior><Animals><Autism><Autistic Disorder><Autosomal dominant Opitz G/BBB syndrome><Basic Research><Basic Science><Beuren syndrome><Biological><Biology><Bourneville Disease><Bourneville Phakomatosis><Bourneville syndrome><Bourneville-Brissaud disease><Bourneville-Pringle syndrome><Cayler cardiofacial syndrome><Cerebroatrophic Hyperammonemia><Charge><Child><Child Youth><Children (0-21)><Children's Hospital><Chromosome 22q11.2 deletion syndrome><Clinic><Clinical><Clinical Research><Clinical Study><Collaborations><Communities><Community Outreach><Coupled><DNA mutation><Dedications><Di George syndrome><DiGeorge Syndrome><DiGeorge anomaly><DiGeorge sequence><Diagnosis><Disability research><Disability study><Disease><Disorder><Disorder of neurometabolic regulation><Disorder of neurometabolism regulation><Early Diagnosis><Early Infantile Autism><Educational workshop><Elfin Facies Syndrome><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Epiloia><Evaluation><Faculty><Faculty Recruitment><Family><Fanconi Schlesinger syndrome><Fanconi-Schlesinger syndrome><Fortification><Fostering><Funding><Ganglia><Gene Transcription><Genes><Genetic Change><Genetic Transcription><Genetic defect><Genetic mutation><Genomics><Goals><Grant><Head><Hospitals><Human><Human Resources><IDDRC><IDDRP><Image><Infant><Infantile Autism><Infantile spasms><Institution><Intellectual and Developmental Disabilities Research Centers><Intellectual disability><Intellectual functioning disability><Intellectual limitation><Intermediary Metabolism><Investigators><Kanner's Syndrome><L-Lysine><Laboratory Research><Leadership><Lightning Attacks><Link><Lysine><MRDD Research Center><MRDDRC><Manpower><Medical><Medical center><Medicine><Mental Retardation and Developmental Disabilities Research Centers><Metabolic Processes><Metabolism><Mission><Modern Man><Monitor><Multiple Neurofibromas><Mutation><NICHD><National Institute of Child Health and Human Development><Neonatal Screening><Nerve Cells><Nerve Unit><Neural Cell><Neural Ganglion><Neurocyte><Neurodevelopmental Disorder><Neurofibromatoses><Neurofibromatosis><Neurofibromatosis Syndrome><Neurological Development Disorder><Neurons><Newborn Infant Screening><Newsletter><On-Line Systems><Online Systems><Outcome><Participant><Pathogenesis><Pathway interactions><Patient Care><Patient Care Delivery><Patients><Pediatric Hospitals><Phenotype><Postdoc><Postdoctoral Fellow><Pringle disease><Quality Control><R-Series Research Projects><R01 Mechanism><R01 Program><RNA Expression><Recruitment Activity><Rehabilitation Centers><Research><Research Associate><Research Grants><Research Personnel><Research Project Grants><Research Projects><Research on disabilities><Researchers><Rett Disorder><Rett Syndrome><Role><Science><Scientist><Sedlackova syndrome><Services><Shprintzen syndrome><Solid><Structure><Students><Study on disabilities><Talents><Technology><Time><Training><Training Programs><Transcription><Translating><Translational Research><Translational Science><Tuberous Sclerosis><Universities><Visualization><West Syndrome><Williams Barratt syndrome><Williams Contiguous Gene Syndrome><Williams Syndrome><Williams-Barratt syndrome><Williams-Beuren Syndrome><Workshop><X-linked infantile spasms><active recruitment><adenoma sebaceum><animal tissue><arm><autism spectral disorder><autism spectrum disorder><autistic spectrum disorder><biologic><brain cell><care for patients><care of patients><caring for patients><cell engineering><cell imaging><cellular engineering><cellular imaging><cerebral sclerosis><clinical care><clinical phenotype><clinical training><clinical translation><clinically translatable><college><collegiate><conference><conotruncal anomaly face syndrome><convention><cost effectiveness><design><designing><developmental disease><developmental disorder><early detection><eclampsia nutans><elfin-facies hypercalcemia syndrome><epigenetically><epiploia><facilities for imaging><familial third and fourth pharyngeal pouch syndrome><flexion spasm><forging><genome mutation><greeting spasms><hereditary multiple system hamartomatosis><human tissue><hypercalcemia-peculiar facies-supravalvular aortic stenosis syndrome><hypercalcemia/Williams-Beuren syndrome><idiopathic hypercalcemia-supravalvular aortic stenosis syndrome><imaging><imaging center><imaging facilities><imaging-related facilities><improved><infantile salaam><infantile spasms with mental retardation><infantile spasms-hypsarrhythmia-mental retardation syndrome><innovate><innovation><innovative><insight><intellectual and developmental disability><jackknife spasm><kids><limited intellectual functioning><member><mental retardation-typical facies-aortic stenosis syndrome><multi-modality><multidisciplinary><multimodality><neurinomatosis centralis><neurodevelopmental disease><neurogenomics><neuromatosis universalis><neurometabolic disease><neurometabolic disorder><neurometabolism disease><neurometabolism disorder><neuronal><neurospongioblastosis diffusa><newborn screening><next generation><novel><online computer><operation><operations><outreach><outreach program><pathway><personnel><phacomatosis><pharyngeal pouch syndrome><post-doc><post-doctoral><post-doctoral trainee><precision medicine><precision-based medicine><prevent><preventing><programs><recruit teachers><rehabilitative center><research associates><research study><sclerosis tuberosa><screening program><social role><spongioblastosis circumscripta><summit><symposia><symposium><teacher recruitment><third and fourth pharyngeal pouch syndrome><thymic and parathyroid agenesis syndrome><tool><translation research><translational investigation><tuberose sclerosis><tuberous sclerosis complex><velo-cardio-facial syndrome><velocardiofacial syndrome><velofacial hypoplasia><web based><youngster>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

RAIF SALIM GEHA

BOSTON CHILDREN'S HOSPITAL, BOSTON, MA

Good lead · 66/100
Likely hiring
Above-average budget
Recent
Active award
$781,407
FY 2026

Project Title

Mechanisms of enhanced food allergy by S. aureus skin colonization in Atopic Dermatitis

Grant Number:

5R01AI175556-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/22/2023

End Date:

2/29/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

Abstract The skin of AD patients is often colonized by S. aureus strains that produce superantigens (SAg), primarily staphylococcal enterotoxin B (SEB). There is a positive association between S. aureus skin colonization and food allergy in AD. The mechanism of this association is unknown. We have ...

Research Terms

<Address><Affinity><Allergic><Allergic Reaction><Allergic to food><Allergy to food><Anaphylactic Reaction><Anaphylactic Shock><Anaphylaxis><Antibodies><Antigens><Apoptosis-Related Cysteine Protease Gene Caspase 8><Apoptotic Cysteine Protease Gene><Apoptotic Protease MCH-5 Gene><Atopic Dermatitis><Atopic Eczema><Atopic Neurodermatitis><Attenuated><B cell growth factor><B-Cell Differentiation Factor-1><B-Cell Growth Factor-1><B-Cell Growth Factor-I><B-Cell Proliferating Factor><B-Cell Stimulating Factor><B-Cell Stimulating Factor-1><B-Cell Stimulation Factor-1><B-Cell Stimulatory Factor-1><BCDF-1><BCGF><BCGF-1><BCSF 1><BSF-1><BSF1><Bacteria><Basophilic Granulocyte><Basophils><Binding><Binetrakin><Blood Basophil><Blood Serum><Bp50><CAP4><CAP4 protease><CASP8><CASP8 Protein><CASP8 gene><CD40><CDW40><Caspase><Caspase Gene><Caspase-8 Gene><Caspase-8/Flice><Cell Body><Cell Communication and Signaling><Cell Signaling><Cell-Death Protease><Cells><Clinical Treatment Moab><Cysteine Endopeptidases><Cysteine Protease><Cysteine Proteinases><Data><Dendritic Cells><Disease><Disorder><Disseminated Neurodermatitis><EC 2.7.1.117><Eosinophil-Mast Cell Growth-Factor><Epithelial Cells><Epithelium><Erythrocyte Burst-Promoting Factor><Event><Exposure to><FADD-Homologous ICE/CED3-Like Protease Gene><FADD-Like ICE><FADD-Like ICE Gene><FADD-homologous ICE/CED3-Like Protease><FLICE><FLICE protein><Food><Food Allergy><Food Hypersensitivity><Gut Epithelial Permeability><Gut Hyperpermeability><Gut permeability><Hematopoietic Cytokine><ICE-Like Apoptotic Protease 5 Gene><ICE-like protease><IL-3><IL-3 Gene><IL-4><IL3><IL3 Gene><IL3 Protein><IL4 Protein><IgE><Immunoglobulin E><In Vitro><Inflammation><Interleukin-4><Interleukin-4 Precursor><Intestinal Absorption><Intestinal Epithelial Permeability><Intestinal Hyperpermeability><Intestinal permeability><Intracellular Communication and Signaling><Lymphocyte Stimulatory Factor 1><MACH protein><MACH-Alpha-1/2/3 Protein Gene><MACH-Beta-1/2/3/4 Protein Gene><MCGF-2><MCH5><MCH5 Isoform Alpha Gene><MGC9013><MORT1-Associated CED-3 Homolog Gene><MORT1-Associated CED3 Homolog Gene><MYLK2><Marrow Mast Cell><Mast Cell Growth Factor-2><Mast-Cell Colony-Stimulating Factor><Mch5 protease><Mediating><Mediator><Mice><Mice Mammals><Molecular Interaction><Monoclonal Antibodies><Murine><Mus><Myosin Kinase><Myosin LCK><Myosin Light Chain Kinase><Myosin Light Chain Kinase, Smooth Muscle and Non-Muscle Isozymes><Myosin Light Polypeptide Kinase><Myosin Regulatory Light-Chain Kinase><Myosin light chain kinase 2, skeletal/cardiac muscle><Occluding Junctions><Oral><Ovalbumin><P-CSF><P-Cell Stimulating Factor><Pathway interactions><Patients><Predisposition><Proteins><Receptor Protein><Role><S aureus><S. aureus><SEB superantigen><Scheme><Serum><Signal Transduction><Signal Transduction Systems><Signaling><Skin><Skin colonization><Staph aureus><Staphylococcal Enterotoxin B><Staphylococcus aureus><Stromal Cells><Superantigens><Susceptibility><T-Cell Growth Factor 2><T-Cells><T-Lymphocyte><TNFRSF5><TNFRSF5 gene><Technical Expertise><Testing><Tight Junctions><Tissue Basophils><Toxin><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><Veiled Cells><Zonula Occludens><absorption><allergic dermatitis><allergic eczema><anaphylactic response to food><anaphylaxis caused by food><anaphylaxis due to food><anaphylaxis to food><antigen challenge><attenuate><attenuates><biological signal transduction><caspase-8><cystein protease><cystein proteinase><cysteine endopeptidase><draining lymph node><food allergy anaphylaxis><food anaphylactic reaction><food anaphylaxis><food antigen><food associated anaphylaxis><food induced anaphylaxis><food mediated anaphylaxis><food related anaphylaxis><food triggered anaphylaxis><gastrointestinal absorption><immunogen><in vivo><inhibitor><intestinal barrier><intestinal epithelium><intestinal mucosal barrier><keratinocyte><mAbs><mast cell><mastocyte><monoclonal Abs><mouse model><murine model><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><p50><passive sensitization><pathway><receptor><recruit><regional lymph node><response><small molecule><smooth muscle myosin light chain kinase><social role><staph enterotoxin B><staphylococcus enterotoxin B><super antigen SEB><synergism><technical skills><thymus derived lymphocyte>
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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

SHARON K HUNTER

UNIVERSITY OF COLORADO DENVER, Aurora, CO

Good lead · 66/100
Likely hiring
Above-average budget
Recent
Active award
$677,467
FY 2026

Project Title

Clinical Trial of Maternal Choline Supplements to Mitigate Effects of Prenatal Cannabis Exposure on Early Brain Development.

Grant Number:

5R01DA058641-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/1/2024

End Date:

2/28/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Cannabis use during pregnancy is increasing with its legalization in many states and the belief by many that it is a safe and effective treatment for pregnancy-related nausea. This proposal investigates to what extent prenatal maternal supplementation with phosphatidylcholine (PChol)...

Research Terms

<0-11 years old><0-4 weeks old><12-20 years old><3rd trimester><9-ene-Tetrahydrocannabinol><Abate><Address><Adolescence><Adverse Late Effects><Adverse effects><Ammon Horn><Amniotic Fluid><Anxiety><Aqua Amnii><Attention><Auditory><Auditory Evoked Potentials><Auditory Evoked Response><Behavior><Behavioral><Belief><Birth><Blood Plasma><Blood Serum><Brain><Brain Nervous System><Breast Milk><Breastmilk><CB1><CB1 Receptor><CB1R><CNR1 gene><Cannabidiol><Cannabinoid Receptor CB1><Cannabinoids><Cannabis><Cell Communication and Signaling><Cell Signaling><Cerebrum><Child><Child Behavior><Child Development><Child Youth><Childhood><Children (0-21)><Choline><Choline Glycerophospholipids><Choline Phosphoglycerides><Cigarette><Clinical><Clinical Trials><Cognition><Cognitive><Conceptions><Connector Neuron><Controlled Clinical Trials><Corn Oil><Cornu Ammonis><Counseling><D9-tetrahydrocannabinol><Data><Delta-9-Tetrahydrocannabinol><Developing fetus><Development><Diet><EEG><Effectiveness><Electroencephalogram><Electroencephalography><Electrophysiology><Electrophysiology (science)><Encephalon><Ethics><Exposure to><Fetal Development><Fetus><Food><Gestation><Hair><Hippocampus><Human Milk><Human Mother's Milk><Infant><Infant and Child Development><Informal Social Control><Intake><Intercalary Neuron><Intercalated Neurons><Interneurons><Internuncial Cell><Internuncial Neuron><Intracellular Communication and Signaling><Knowledge><Laboratories><Last Trimester><Late Effects><Lecithin><Legal><Liquor Amnii><Maize Oil><Mammary Gland Milk><Marijuana><Maternal cannabis use><Measures><Meat><Medical><Mental Depression><Mental disorders><Mental health disorders><Morning Sickness><Mother's Milk><Mothers><Natural Remedy><Nausea><Nausea and Vomiting in pregnancy><Nerve Impulse Transmission><Nerve Transmission><Neural Transmission><Neuronal Transmission><Neurophysiology / Electrophysiology><Newborn Infant><Newborns><Nicotinic Acetylcholine Receptors><Nicotinic Receptors><Observational research><Outcome><Parents><Parturition><Patient Self-Report><Perinatal Care><Phosphatidylcholines><Placebos><Planned Pregnancy><Plasma><Plasma Serum><Pregnancy><Pregnant Women><Provider><Psyche structure><Psychiatric Disease><Psychiatric Disorder><Public Health><Questionnaires><Randomized><Randomized, Controlled Trials><Regulation><Reporting><Reticuloendothelial System, Serum, Plasma><Risk><Safety><Scalp><Scalp structure><Self Regulation><Self-Report><Serum><Sham Treatment><Signal Transduction><Signal Transduction Systems><Signaling><Social Behavior><Source><Soy Beans><Soybeans><Standardization><Stimulus><Stress><Supplementation><Synaptic Transmission><THC co-use><THC exposure><THC use><Temperament><Testing><Tetrahydrocannabinol><Tetrahydrocannabinol co-use><Tetrahydrocannabinol use><Third Pregnancy Trimester><Third Trimester><Toddler><Urine><Woman><Women's study><Work><adolescence (12-20)><axon signaling><axon-glial signaling><axonal signaling><before conception><biological signal transduction><cannabinoid receptor 1><cannabinoid receptor type 1><cannabinoid type 1><cannabis cessation><cannabis in utero><cannabis use><cannabis use during pregnancy><cannabis use in pregnancy><cerebral><choline supplementation><cholinergic><critical period><delta(1)-THC><delta(1)-Tetrahydrocannabinol><delta(9)-THC><delta(9)-Tetrahydrocannabinol><depression><developmental><dietary><diets><double-blind placebo control trial><double-blind placebo controlled trial><double-masked controlled trial><effective therapy><effective treatment><egg><electrophysiological><ethical><expectant mother><expectant women><expecting mother><expecting women><exposed in utero><female study><fetal><fetal cannabis exposure><fetal exposure><fetal marijuana exposure><gestational marijuana exposure><glia signaling><glial signaling><hippocampal><improved><in utero exposure><individuals who are pregnant><inhibitory neuron><innervation><innovate><innovation><innovative><intra-uterine environmental exposure><intrauterine environmental exposure><investigate observational><investigate prospective><kids><later in life><later life><marihuana><marijuana use><marijuana use during pregnancy><marijuana use in pregnancy><maternal marijuana use><maternal milk><mental><mental illness><nausea and vomiting during pregnancy><neonate><nerve signaling><nerve supply><neural signaling><neuronal signaling><neurotransmission><newborn child><newborn children><novel><observational investigation><offspring><paired stimuli><parent><pediatric><people who are pregnant><pill><placebo group><post-natal period><postnatal><postnatal period><preconception><pregnant females><pregnant mothers><pregnant people><pregnant populations><prenatal><prenatal cannabis exposure><prenatal cannabis use><prenatal exposure><prenatal intervention><prenatal marijuana exposure><prenatal marijuana use><prenatally exposed><prenatally exposed to cannabis><prenatally exposed to marijuana><prenatally marijuana exposed><prevent><preventing><prior to conception><prospective investigation><prospective research><protective effect><psychiatric illness><psychological disorder><randomisation><randomization><randomized control trial><randomly assigned><response><sensory gating><sham group><sham therapy><sociobehavior><sociobehavioral><study among females><study among women><study in females><study in women><study observational><study on females><study on women><study prospective><study within women><substance use><substance using><supplementation with choline><survey observational><survey prospective><tetrahydrocannabinol exposure><those who are pregnant><translational model><treatment group><unborn><women who are pregnant><youngster><Δ(1)-THC><Δ(1)-tetrahydrocannabinol><Δ(9)-THC><Δ(9)-tetrahydrocannabinol><Δ-9-tetrahydrocannabinol><Δ9-tetrahydrocannabinol>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Maria Camille Hoffman

UNIVERSITY OF COLORADO DENVER, Aurora, CO

Good lead · 66/100
Likely hiring
Above-average budget
Recent
Active award
$677,467
FY 2026

Project Title

Clinical Trial of Maternal Choline Supplements to Mitigate Effects of Prenatal Cannabis Exposure on Early Brain Development.

Grant Number:

5R01DA058641-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/1/2024

End Date:

2/28/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Cannabis use during pregnancy is increasing with its legalization in many states and the belief by many that it is a safe and effective treatment for pregnancy-related nausea. This proposal investigates to what extent prenatal maternal supplementation with phosphatidylcholine (PChol)...

Research Terms

<0-11 years old><0-4 weeks old><12-20 years old><3rd trimester><9-ene-Tetrahydrocannabinol><Abate><Address><Adolescence><Adverse Late Effects><Adverse effects><Ammon Horn><Amniotic Fluid><Anxiety><Aqua Amnii><Attention><Auditory><Auditory Evoked Potentials><Auditory Evoked Response><Behavior><Behavioral><Belief><Birth><Blood Plasma><Blood Serum><Brain><Brain Nervous System><Breast Milk><Breastmilk><CB1><CB1 Receptor><CB1R><CNR1 gene><Cannabidiol><Cannabinoid Receptor CB1><Cannabinoids><Cannabis><Cell Communication and Signaling><Cell Signaling><Cerebrum><Child><Child Behavior><Child Development><Child Youth><Childhood><Children (0-21)><Choline><Choline Glycerophospholipids><Choline Phosphoglycerides><Cigarette><Clinical><Clinical Trials><Cognition><Cognitive><Conceptions><Connector Neuron><Controlled Clinical Trials><Corn Oil><Cornu Ammonis><Counseling><D9-tetrahydrocannabinol><Data><Delta-9-Tetrahydrocannabinol><Developing fetus><Development><Diet><EEG><Effectiveness><Electroencephalogram><Electroencephalography><Electrophysiology><Electrophysiology (science)><Encephalon><Ethics><Exposure to><Fetal Development><Fetus><Food><Gestation><Hair><Hippocampus><Human Milk><Human Mother's Milk><Infant><Infant and Child Development><Informal Social Control><Intake><Intercalary Neuron><Intercalated Neurons><Interneurons><Internuncial Cell><Internuncial Neuron><Intracellular Communication and Signaling><Knowledge><Laboratories><Last Trimester><Late Effects><Lecithin><Legal><Liquor Amnii><Maize Oil><Mammary Gland Milk><Marijuana><Maternal cannabis use><Measures><Meat><Medical><Mental Depression><Mental disorders><Mental health disorders><Morning Sickness><Mother's Milk><Mothers><Natural Remedy><Nausea><Nausea and Vomiting in pregnancy><Nerve Impulse Transmission><Nerve Transmission><Neural Transmission><Neuronal Transmission><Neurophysiology / Electrophysiology><Newborn Infant><Newborns><Nicotinic Acetylcholine Receptors><Nicotinic Receptors><Observational research><Outcome><Parents><Parturition><Patient Self-Report><Perinatal Care><Phosphatidylcholines><Placebos><Planned Pregnancy><Plasma><Plasma Serum><Pregnancy><Pregnant Women><Provider><Psyche structure><Psychiatric Disease><Psychiatric Disorder><Public Health><Questionnaires><Randomized><Randomized, Controlled Trials><Regulation><Reporting><Reticuloendothelial System, Serum, Plasma><Risk><Safety><Scalp><Scalp structure><Self Regulation><Self-Report><Serum><Sham Treatment><Signal Transduction><Signal Transduction Systems><Signaling><Social Behavior><Source><Soy Beans><Soybeans><Standardization><Stimulus><Stress><Supplementation><Synaptic Transmission><THC co-use><THC exposure><THC use><Temperament><Testing><Tetrahydrocannabinol><Tetrahydrocannabinol co-use><Tetrahydrocannabinol use><Third Pregnancy Trimester><Third Trimester><Toddler><Urine><Woman><Women's study><Work><adolescence (12-20)><axon signaling><axon-glial signaling><axonal signaling><before conception><biological signal transduction><cannabinoid receptor 1><cannabinoid receptor type 1><cannabinoid type 1><cannabis cessation><cannabis in utero><cannabis use><cannabis use during pregnancy><cannabis use in pregnancy><cerebral><choline supplementation><cholinergic><critical period><delta(1)-THC><delta(1)-Tetrahydrocannabinol><delta(9)-THC><delta(9)-Tetrahydrocannabinol><depression><developmental><dietary><diets><double-blind placebo control trial><double-blind placebo controlled trial><double-masked controlled trial><effective therapy><effective treatment><egg><electrophysiological><ethical><expectant mother><expectant women><expecting mother><expecting women><exposed in utero><female study><fetal><fetal cannabis exposure><fetal exposure><fetal marijuana exposure><gestational marijuana exposure><glia signaling><glial signaling><hippocampal><improved><in utero exposure><individuals who are pregnant><inhibitory neuron><innervation><innovate><innovation><innovative><intra-uterine environmental exposure><intrauterine environmental exposure><investigate observational><investigate prospective><kids><later in life><later life><marihuana><marijuana use><marijuana use during pregnancy><marijuana use in pregnancy><maternal marijuana use><maternal milk><mental><mental illness><nausea and vomiting during pregnancy><neonate><nerve signaling><nerve supply><neural signaling><neuronal signaling><neurotransmission><newborn child><newborn children><novel><observational investigation><offspring><paired stimuli><parent><pediatric><people who are pregnant><pill><placebo group><post-natal period><postnatal><postnatal period><preconception><pregnant females><pregnant mothers><pregnant people><pregnant populations><prenatal><prenatal cannabis exposure><prenatal cannabis use><prenatal exposure><prenatal intervention><prenatal marijuana exposure><prenatal marijuana use><prenatally exposed><prenatally exposed to cannabis><prenatally exposed to marijuana><prenatally marijuana exposed><prevent><preventing><prior to conception><prospective investigation><prospective research><protective effect><psychiatric illness><psychological disorder><randomisation><randomization><randomized control trial><randomly assigned><response><sensory gating><sham group><sham therapy><sociobehavior><sociobehavioral><study among females><study among women><study in females><study in women><study observational><study on females><study on women><study prospective><study within women><substance use><substance using><supplementation with choline><survey observational><survey prospective><tetrahydrocannabinol exposure><those who are pregnant><translational model><treatment group><unborn><women who are pregnant><youngster><Δ(1)-THC><Δ(1)-tetrahydrocannabinol><Δ(9)-THC><Δ(9)-tetrahydrocannabinol><Δ-9-tetrahydrocannabinol><Δ9-tetrahydrocannabinol>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Allan Doctor

DUKE UNIVERSITY, DURHAM, NC

Good lead · 66/100
Likely hiring
Above-average budget
Recent
Active award
$649,565
FY 2026

Project Title

Red blood cell ATP export and transfusion in sepsis

Grant Number:

5R01HL161071-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/5/2023

End Date:

12/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT O2 uptake in the lung and O2 delivery peripherally depend on the efficient matching of blood flow to regional O2 availability in the lung and O2 consumption in tissues. To achieve this matching, red blood cell (RBC) hemoglobin allostery regulates not only trans-erythrocytic O2 flux but also...

Research Terms

<0-11 years old><1H-Purin-6-amine><21+ years old><ARDS><Acute Lung Injury><Acute Pulmonary Injury><Acute Respiratory Distress><Acute Respiratory Distress Syndrome><Adenine><Adhesions><Adhesives><Adult><Adult ARDS><Adult Human><Adult RDS><Adult Respiratory Distress Syndrome><Anemia><Attenuated><Autoregulation><Blood><Blood Reticuloendothelial System><Blood Sample><Blood Transfusion><Blood Vessels><Blood erythrocyte><Blood flow><Blood leukocyte><Blood specimen><Body Tissues><CLP model><CLP mouse model><Caliber><Cardiac Output><Cecal ligation perforation><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><Cellular injury><Child><Child Youth><Children (0-21)><Clinical><Consumption><Coupling><Critical Illness><Critically Ill><Cryopreserved Cell><Da Nang Lung><Depressed mood><Dysfunction><Endothelial Cells><Endothelium><Ensure><Erythrocyte Transfusion><Erythrocytes><Erythrocytic><Exposure to><Functional disorder><Genetic><Grippe><Hemoglobin><Homeostasis><Human><Hypoxemia><Hypoxia><Hypoxic><Immune response><Impairment><In Vitro><Incubated><Infection><Inflammation><Influenza><Inosine><Intervention><Intracellular Communication and Signaling><Investigation><Leukocytes><Leukocytes Reticuloendothelial System><Lung><Lung Respiratory System><Marrow erythrocyte><Marrow leukocyte><Mediating><Mediator><Metabolic><Methods><Mice><Mice Mammals><Modeling><Modern Man><Morbidity><Murine><Mus><O element><O2 element><Oral><Organ><Outcome><Oxygen><Oxygen Deficiency><Patients><Peripheral><Persons><Phase><Phenotype><Phosphates><Physiological Homeostasis><Physiopathology><Pyruvate><Pyruvate Kinase><Red Blood Cell Transfusion><Red Blood Cells><Red Cell><Research Specimen><Respiration Disorders><Respiratory Disorder><Respiratory physiology><Risk><Risk Factors><Role><Sampling><Scheme><Sepsis><Shock Lung><Signal Transduction><Signal Transduction Systems><Signaling><Site><Specimen><Stiff lung><Testing><Therapeutic><Tissues><Transfusion><Translations><Vitamin B4><White Blood Cells><White Cell><adulthood><attenuate><attenuates><biobank><biological signal transduction><biorepository><blood corpuscles><breathing disorder><candidate identification><cecal ligation and perforation><cecal ligation and puncture><cecal ligation puncture><cecum ligation and puncture><cecum ligation puncture><cell damage><cell injury><cell type><cellular damage><children with sepsis><clinical investigation><clinical relevance><clinical translation><clinically relevant><clinically translatable><damage to cells><depressed><design><designing><empowerment><experiment><experimental research><experimental study><experiments><genetic approach><genetic strategy><heart output><host response><hypoxemic><immune system response><immunoresponse><improved><in vivo><individuals with sepsis><injury to cells><inorganic phosphate><insight><kids><lead candidate><mortality><mouse model><murine model><novel><pathophysiology><patients with sepsis><pediatric sepsis><pediatric septic><people with sepsis><pharmacologic><phosphoenol transphosphorylase><phosphoenolpyruvate kinase><preservation><prospective><pulmonary><respiratory><respiratory dysfunction><respiratory function><response><sadness><sepsis groups><sepsis in children><sepsis patients><sepsis population><sepsis subjects><septic><septic children><septic group><septic individuals><septic patients><septic people><septic population><septic subject><severe sepsis><severely septic><social role><subjects with sepsis><tissue oxygen saturation><tissue oxygenation><translation><uptake><vascular><wet lung><white blood cell><white blood corpuscle><youngster>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

TIMOTHY J MCMAHON

DUKE UNIVERSITY, DURHAM, NC

Good lead · 66/100
Likely hiring
Above-average budget
Recent
Active award
$649,565
FY 2026

Project Title

Red blood cell ATP export and transfusion in sepsis

Grant Number:

5R01HL161071-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/5/2023

End Date:

12/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT O2 uptake in the lung and O2 delivery peripherally depend on the efficient matching of blood flow to regional O2 availability in the lung and O2 consumption in tissues. To achieve this matching, red blood cell (RBC) hemoglobin allostery regulates not only trans-erythrocytic O2 flux but also...

Research Terms

<0-11 years old><1H-Purin-6-amine><21+ years old><ARDS><Acute Lung Injury><Acute Pulmonary Injury><Acute Respiratory Distress><Acute Respiratory Distress Syndrome><Adenine><Adhesions><Adhesives><Adult><Adult ARDS><Adult Human><Adult RDS><Adult Respiratory Distress Syndrome><Anemia><Attenuated><Autoregulation><Blood><Blood Reticuloendothelial System><Blood Sample><Blood Transfusion><Blood Vessels><Blood erythrocyte><Blood flow><Blood leukocyte><Blood specimen><Body Tissues><CLP model><CLP mouse model><Caliber><Cardiac Output><Cecal ligation perforation><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><Cellular injury><Child><Child Youth><Children (0-21)><Clinical><Consumption><Coupling><Critical Illness><Critically Ill><Cryopreserved Cell><Da Nang Lung><Depressed mood><Dysfunction><Endothelial Cells><Endothelium><Ensure><Erythrocyte Transfusion><Erythrocytes><Erythrocytic><Exposure to><Functional disorder><Genetic><Grippe><Hemoglobin><Homeostasis><Human><Hypoxemia><Hypoxia><Hypoxic><Immune response><Impairment><In Vitro><Incubated><Infection><Inflammation><Influenza><Inosine><Intervention><Intracellular Communication and Signaling><Investigation><Leukocytes><Leukocytes Reticuloendothelial System><Lung><Lung Respiratory System><Marrow erythrocyte><Marrow leukocyte><Mediating><Mediator><Metabolic><Methods><Mice><Mice Mammals><Modeling><Modern Man><Morbidity><Murine><Mus><O element><O2 element><Oral><Organ><Outcome><Oxygen><Oxygen Deficiency><Patients><Peripheral><Persons><Phase><Phenotype><Phosphates><Physiological Homeostasis><Physiopathology><Pyruvate><Pyruvate Kinase><Red Blood Cell Transfusion><Red Blood Cells><Red Cell><Research Specimen><Respiration Disorders><Respiratory Disorder><Respiratory physiology><Risk><Risk Factors><Role><Sampling><Scheme><Sepsis><Shock Lung><Signal Transduction><Signal Transduction Systems><Signaling><Site><Specimen><Stiff lung><Testing><Therapeutic><Tissues><Transfusion><Translations><Vitamin B4><White Blood Cells><White Cell><adulthood><attenuate><attenuates><biobank><biological signal transduction><biorepository><blood corpuscles><breathing disorder><candidate identification><cecal ligation and perforation><cecal ligation and puncture><cecal ligation puncture><cecum ligation and puncture><cecum ligation puncture><cell damage><cell injury><cell type><cellular damage><children with sepsis><clinical investigation><clinical relevance><clinical translation><clinically relevant><clinically translatable><damage to cells><depressed><design><designing><empowerment><experiment><experimental research><experimental study><experiments><genetic approach><genetic strategy><heart output><host response><hypoxemic><immune system response><immunoresponse><improved><in vivo><individuals with sepsis><injury to cells><inorganic phosphate><insight><kids><lead candidate><mortality><mouse model><murine model><novel><pathophysiology><patients with sepsis><pediatric sepsis><pediatric septic><people with sepsis><pharmacologic><phosphoenol transphosphorylase><phosphoenolpyruvate kinase><preservation><prospective><pulmonary><respiratory><respiratory dysfunction><respiratory function><response><sadness><sepsis groups><sepsis in children><sepsis patients><sepsis population><sepsis subjects><septic><septic children><septic group><septic individuals><septic patients><septic people><septic population><septic subject><severe sepsis><severely septic><social role><subjects with sepsis><tissue oxygen saturation><tissue oxygenation><translation><uptake><vascular><wet lung><white blood cell><white blood corpuscle><youngster>
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MARK J SHLOMCHIK

UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PITTSBURGH, PA

Good lead · 66/100
Likely hiring
Above-average budget
Recent
Active award
$549,892
FY 2026

Project Title

Signaling and Selection in Germinal Center B cells

Grant Number:

2R01AI105018-11

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/15/2014

End Date:

1/31/2031

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

The germinal center (GC) response generates long-lived, high affinity humoral immunity. GC B cells (GCBC) undergo affinity-based positive selection and can differentiate into either memory B cells (MBC) or long-lived plasma cells (LLPC). To enact positive selection and differentiation, a subset of G...

Research Terms

<Ab-mediated immunity><Ab-mediated protection><Acute><Address><Affect><Affinity><Anatomic Sites><Anatomic structures><Anatomy><Antibodies><Antibody immunity><Antibody protection><Antibody-mediated protection><Assay><Autoimmune Status><Autoimmunity><B blood cells><B cell><B cell differentiation><B cell lymphoma 6><B cell receptor><B cells><B lymphocyte differentiation><B-Cell Antigen Receptor><B-Cell CLL/Lymphoma-6 Gene><B-Cell Development><B-Cells><B-Lymphocytes><B-cell><BCL5><BCL6><BCL6 gene><BLIMP1><Basal Transcription Factor><Basal transcription factor genes><Bioassay><Biological Assay><Biology><Biomass><Blood Plasma Cell><Bp50><CD40><CDW40><CRISPR editing screen><CRISPR screen><CRISPR-based screen><CRISPR/Cas9 screen><Cell Body><Cell Communication and Signaling><Cell Compartmentation><Cell Compartmentations><Cell Count><Cell Differentiation><Cell Differentiation process><Cell Function><Cell Number><Cell Physiology><Cell Process><Cell Signaling><Cells><Cellular Function><Cellular Physiology><Cellular Process><Cellular biology><Cys-His2 Zinc Finger Transcription Factor Gene><DNA mutation><Development><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Event><Future><Gene Expression><Gene Modified><General Transcription Factor Gene><General Transcription Factors><Genetic Change><Genetic defect><Genetic mutation><Genomics><Germinal Center><Goals><Humoral Immunities><IL-21 receptor><IL21><IL21R><IRF4><IRF4 gene><Immune><Immune response><Immune system><Immunes><Immunity><In Vitro><Infection><Innate Immunity><Interferon Regulatory Factor 4><Intracellular Communication and Signaling><Knowledge><LAZ-3 Gene><LAZ3><LSIRF Protein><Lead><Link><Lymphomagenesis><MGC9013><Maps><Mediating><Memory><Memory B Cell><Memory B-Lymphocyte><Metabolic><Methods><Mice><Mice Mammals><Microanatomy><Microscopic Anatomy><Modeling><Molecular><Multiple Myeloma Oncogene 1><Murine><Mus><Mutation><Native Immunity><Natural Immunity><Nature><Non-Specific Immunity><Nonspecific Immunity><Output><PRDI-BF1><PRDM1><PRDM1 gene><Pathway interactions><Pattern><Pb element><Plasma Cells><Plasmacytes><Play><Principal Investigator><Process><Proteins><Reaction><Reagent><Receptor Protein><Receptor Signaling><Reporter><Role><Signal Induction><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><Source><Stimulus><Structure of germinal center of lymph node><Subcellular Process><Surface><T-Cells><T-Lymphocyte><TNFRSF5><TNFRSF5 gene><Testing><Time><Transcription Factor Proto-Oncogene><Transcription Repressor><Transcription factor genes><Transcriptional Repressor><Transitional Cell><Tumor Immunity><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><Vaccination><Vaccines><Variant><Variation><Work><ZNF51><ZNF51 Gene><Zinc Finger Protein 51 Gene><anti-tumor immunity><antibody-based immunity><antibody-mediated immunity><antitumor immunity><biological signal transduction><c myc><c-myc Genes><cancer immunity><cartilage link protein><cell biology><cell type><cellular differentiation><clustered regularly interspaced short palindromic repeats screen><cmyc><developmental><epigenetically><epigenome><experiment><experimental research><experimental study><experiments><fascinate><gene modification><gene regulatory network><genetic repressor><genetically modified><genome mutation><global gene expression><global transcription profile><glucose transport><heavy metal Pb><heavy metal lead><host response><immune system response><immunoresponse><in vivo><interleukin-21><interleukin-21 receptor><link protein><metabolic profile><mutant><new approaches><novel><novel approaches><novel strategies><novel strategy><p50><pathogen><pathway><plasmocyte><programs><receptor><response><social role><thymus derived lymphocyte><transcription factor><transcriptome><transcriptomics><v-myc Avian Myelocytomatosis Viral Oncogene Cellular Homolog>
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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Ali Azhdarinia

UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON, HOUSTON, TX

Good lead · 66/100
Likely hiring
Solid budget
Very recent
Active award
$482,257
FY 2026

Project Title

Receptor-Targeted Fluorescence-Guided Surgery in Pancreatic Neuroendocrine Tumors

Grant Number:

5R01CA263512-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

7/1/2022

End Date:

2/28/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY The goal of this proposal is to clinically translate a fluorescently labeled contrast agent that improves surgical outcomes in patients with pancreatic neuroendocrine tumors (pNETs). Surgery is the main treatment option for these patients and can be curative if tumors are completely ...

Research Terms

<Abscission><Address><Back><Binding><Blood Serum><Body Tissues><Cancer Center><Cancer Treatment><Canine Species><Canis familiaris><Caring><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><Charge><Chelating Agents><Chelators><Clinic><Clinical><Clinical Research><Clinical Study><Clinical Trials><Coloring Agents><Common Rat Strains><Comparative Study><Complexons><Consensus><Contracting Opportunities><Contracts><Contrast Agent><Contrast Drugs><Contrast Media><Data><Detection><Development><Documentation><Dogs><Dogs Mammals><Dorsum><Dose><Drug Compounding><Drug Design><Drug Preparation><Dyes><Early-Stage Clinical Trials><Effectiveness><Excision><Exocrine pancreatic insufficiency><Extirpation><Feedback><Fluorescence><Fluorescence Agents><Fluorescent Agents><Fluorescent Dyes><Freeze Drying><Freeze Dryings><Generations><Goals><Guidelines><Head and Neck Cancer><Head and Neck Carcinoma><Histopathology><Human><IND Filing><IND application><IND package><IND submission><Image><Image-Guided Surgery><Imaging technology><Impairment><Incidence><Injections><Intracellular Communication and Signaling><Intraoperative Complications><Investigational Drugs><Investigational New Drug Application><Investigational New Drugs><Island Cell Tumor><Islet Cell Neoplasm><Islet Cell Tumor><Label><Lyophilization><Malignant Head and Neck Neoplasm><Malignant Neoplasm Therapy><Malignant Neoplasm Treatment><Malignant Ovarian Neoplasm><Malignant Ovarian Tumor><Malignant Tumor of the Ovary><Malignant neoplasm of ovary><Manufacturer><Mediating><Medical Oncologist><Metastasis><Metastasis to Lymph Nodes><Metastasize><Metastatic Lesion><Metastatic Mass><Metastatic Neoplasm><Metastatic Neoplasm to Lymph Nodes><Metastatic Tumor><Metastatic Tumor to Lymph Nodes><Mice><Mice Mammals><Modeling><Modern Man><Molecular Interaction><Molecular Target><Multifocal Lesion><Murine><Mus><Neoplasm Metastasis><Normal Tissue><Normal tissue morphology><Operating Rooms><Operative Procedures><Operative Surgical Procedures><Organ><Ovary Cancer><P50 Mechanism><P50 Program><PDX model><PanNets><Pancreas Excision><Pancreatectomy><Pancreatic Endocrine Neoplasm><Pancreatic Endocrine Tumor><Pancreatic Insufficiency><Pancreatic Neuroendocrine Tumor><Patient derived xenograft><Patient imaging><Patients><Penetration><Peptide Synthesis><Performance><Peroperative Complications><Pharmacology><Pharmacology and Toxicology><Phase><Phase 1 Clinical Trials><Phase I Clinical Trials><Play><Postoperative><Postoperative Period><Pre-Clinical Model><Preclinical Models><Preparation><Procedures><Production><Property><Public Health><QOL><Quality of life><Radiopaque Media><Rat><Rats Mammals><Rattus><Receptor Protein><Recurrent Neoplasm><Recurrent tumor><Removal><Research><Role><SRIH Receptors><SYS-TX><Safety><Secondary Neoplasm><Secondary Tumor><Serum><Serum Proteins><Signal Transduction><Signal Transduction Systems><Signaling><Small Intestines><Solid><Somatostatin Receptor><Somatotropin Release Inhibiting Hormone Receptors><Specialized Center><Specific qualifier value><Specified><Staining method><Stains><Surgeon><Surgical><Surgical Interventions><Surgical Oncology><Surgical Procedure><Surgical Removal><Surgical margins><Synthesis Chemistry><Synthetic Chemistry><Systemic Therapy><Tactile><Testing><Tissues><Toxicology><Translating><Visualization><Work><Xenograft Model><analog><anti-cancer therapy><biological signal transduction><cancer metastasis><cancer therapy><cancer-directed therapy><canine><contrast imaging><cyanine><death risk><design><designing><detection sensitivity><determine efficacy><developmental><domestic dog><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><evaluate efficacy><examine efficacy><first in man><first-in-human><fluorescence-guided surgery><fluorescent dye/probe><fluorophore><good laboratory practice><head/neck cancer><image-based method><imaging><imaging agent><imaging approach><imaging based approach><imaging in patients><imaging method><imaging modality><imaging on patients><improved><in vivo><innovate><innovation><innovative><intra-operative complication><intra-operative imaging><intraoperative imaging><lymph node metastasis><malignant head and neck tumor><manufacture><manufacturing process><minimally invasive><model development><model developments><mortality risk><multi-modality><multimodality><neoplasm recurrence><novel><nuclear imaging><oncologic surgery><ovarian cancer><pancreas surgery><pancreatic NET><pancreatic islet neoplasm><pancreatic surgery><patient derived xenograft model><patient population><phase 1 trial><phase I protocol><phase I trial><pre-clinical><pre-clinical safety><pre-clinical toxicity><preclinical><preclinical safety><preclinical toxicity><preparations><primary end point><primary endpoint><radiolabel><radiolabels><radiotracer><receptor><receptor binding><receptor bound><resection><safety study><scale up><secondary end point><secondary endpoint><small bowel><social role><somatostatin analog><standard of care><surgery><surgery outcome><surgical imaging><surgical outcome><targeted agent><targeted imaging><theranostics><tool><translational opportunities><translational potential><tumor><tumor cell metastasis><tumor specificity><tumor xenograft><uptake><xenograft transplant model><xenotransplant model>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Naruhiko Ikoma

UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON, HOUSTON, TX

Good lead · 66/100
Likely hiring
Solid budget
Very recent
Active award
$482,257
FY 2026

Project Title

Receptor-Targeted Fluorescence-Guided Surgery in Pancreatic Neuroendocrine Tumors

Grant Number:

5R01CA263512-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

7/1/2022

End Date:

2/28/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY The goal of this proposal is to clinically translate a fluorescently labeled contrast agent that improves surgical outcomes in patients with pancreatic neuroendocrine tumors (pNETs). Surgery is the main treatment option for these patients and can be curative if tumors are completely ...

Research Terms

<Abscission><Address><Back><Binding><Blood Serum><Body Tissues><Cancer Center><Cancer Treatment><Canine Species><Canis familiaris><Caring><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><Charge><Chelating Agents><Chelators><Clinic><Clinical><Clinical Research><Clinical Study><Clinical Trials><Coloring Agents><Common Rat Strains><Comparative Study><Complexons><Consensus><Contracting Opportunities><Contracts><Contrast Agent><Contrast Drugs><Contrast Media><Data><Detection><Development><Documentation><Dogs><Dogs Mammals><Dorsum><Dose><Drug Compounding><Drug Design><Drug Preparation><Dyes><Early-Stage Clinical Trials><Effectiveness><Excision><Exocrine pancreatic insufficiency><Extirpation><Feedback><Fluorescence><Fluorescence Agents><Fluorescent Agents><Fluorescent Dyes><Freeze Drying><Freeze Dryings><Generations><Goals><Guidelines><Head and Neck Cancer><Head and Neck Carcinoma><Histopathology><Human><IND Filing><IND application><IND package><IND submission><Image><Image-Guided Surgery><Imaging technology><Impairment><Incidence><Injections><Intracellular Communication and Signaling><Intraoperative Complications><Investigational Drugs><Investigational New Drug Application><Investigational New Drugs><Island Cell Tumor><Islet Cell Neoplasm><Islet Cell Tumor><Label><Lyophilization><Malignant Head and Neck Neoplasm><Malignant Neoplasm Therapy><Malignant Neoplasm Treatment><Malignant Ovarian Neoplasm><Malignant Ovarian Tumor><Malignant Tumor of the Ovary><Malignant neoplasm of ovary><Manufacturer><Mediating><Medical Oncologist><Metastasis><Metastasis to Lymph Nodes><Metastasize><Metastatic Lesion><Metastatic Mass><Metastatic Neoplasm><Metastatic Neoplasm to Lymph Nodes><Metastatic Tumor><Metastatic Tumor to Lymph Nodes><Mice><Mice Mammals><Modeling><Modern Man><Molecular Interaction><Molecular Target><Multifocal Lesion><Murine><Mus><Neoplasm Metastasis><Normal Tissue><Normal tissue morphology><Operating Rooms><Operative Procedures><Operative Surgical Procedures><Organ><Ovary Cancer><P50 Mechanism><P50 Program><PDX model><PanNets><Pancreas Excision><Pancreatectomy><Pancreatic Endocrine Neoplasm><Pancreatic Endocrine Tumor><Pancreatic Insufficiency><Pancreatic Neuroendocrine Tumor><Patient derived xenograft><Patient imaging><Patients><Penetration><Peptide Synthesis><Performance><Peroperative Complications><Pharmacology><Pharmacology and Toxicology><Phase><Phase 1 Clinical Trials><Phase I Clinical Trials><Play><Postoperative><Postoperative Period><Pre-Clinical Model><Preclinical Models><Preparation><Procedures><Production><Property><Public Health><QOL><Quality of life><Radiopaque Media><Rat><Rats Mammals><Rattus><Receptor Protein><Recurrent Neoplasm><Recurrent tumor><Removal><Research><Role><SRIH Receptors><SYS-TX><Safety><Secondary Neoplasm><Secondary Tumor><Serum><Serum Proteins><Signal Transduction><Signal Transduction Systems><Signaling><Small Intestines><Solid><Somatostatin Receptor><Somatotropin Release Inhibiting Hormone Receptors><Specialized Center><Specific qualifier value><Specified><Staining method><Stains><Surgeon><Surgical><Surgical Interventions><Surgical Oncology><Surgical Procedure><Surgical Removal><Surgical margins><Synthesis Chemistry><Synthetic Chemistry><Systemic Therapy><Tactile><Testing><Tissues><Toxicology><Translating><Visualization><Work><Xenograft Model><analog><anti-cancer therapy><biological signal transduction><cancer metastasis><cancer therapy><cancer-directed therapy><canine><contrast imaging><cyanine><death risk><design><designing><detection sensitivity><determine efficacy><developmental><domestic dog><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><evaluate efficacy><examine efficacy><first in man><first-in-human><fluorescence-guided surgery><fluorescent dye/probe><fluorophore><good laboratory practice><head/neck cancer><image-based method><imaging><imaging agent><imaging approach><imaging based approach><imaging in patients><imaging method><imaging modality><imaging on patients><improved><in vivo><innovate><innovation><innovative><intra-operative complication><intra-operative imaging><intraoperative imaging><lymph node metastasis><malignant head and neck tumor><manufacture><manufacturing process><minimally invasive><model development><model developments><mortality risk><multi-modality><multimodality><neoplasm recurrence><novel><nuclear imaging><oncologic surgery><ovarian cancer><pancreas surgery><pancreatic NET><pancreatic islet neoplasm><pancreatic surgery><patient derived xenograft model><patient population><phase 1 trial><phase I protocol><phase I trial><pre-clinical><pre-clinical safety><pre-clinical toxicity><preclinical><preclinical safety><preclinical toxicity><preparations><primary end point><primary endpoint><radiolabel><radiolabels><radiotracer><receptor><receptor binding><receptor bound><resection><safety study><scale up><secondary end point><secondary endpoint><small bowel><social role><somatostatin analog><standard of care><surgery><surgery outcome><surgical imaging><surgical outcome><targeted agent><targeted imaging><theranostics><tool><translational opportunities><translational potential><tumor><tumor cell metastasis><tumor specificity><tumor xenograft><uptake><xenograft transplant model><xenotransplant model>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Amer Aziz Beg

H. LEE MOFFITT CANCER CTR & RES INST, TAMPA, FL

Good lead · 66/100
Likely hiring
Solid budget
Very recent
Active award
$460,204
FY 2026

Project Title

Defining impact of in situ activation of CD40 and type 1 interferon signaling on theTME and systemic T cell immunity in murine models and cancer patients

Grant Number:

5R01CA283730-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/1/2024

End Date:

4/30/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY Recent advances in cancer immunotherapies have revolutionized lung cancer treatment paradigms. However, many patients derive little or no benefit from FDA approved immune checkpoint inhibitors (ICI). A host of clinical studies have shown that pre-existing tumor-reactive T cells are c...

Research Terms

<Agonist><Antitumor Response><Biopsy><Blood><Blood Reticuloendothelial System><Bp50><CD154 Antigens><CD40><CD40 Ligand><CD40-L><CD8 Cell><CD8 T cells><CD8 lymphocyte><CD8+ T cell><CD8+ T-Lymphocyte><CD8-Positive Lymphocytes><CD8-Positive T-Lymphocytes><CDW40><CRAd><Cancer Patient><Cancer Treatment><Cancers><Cell Body><Cell Communication and Signaling><Cell Signaling><Cell surface><Cells><Checkpoint inhibitor><Clinical><Clinical Research><Clinical Study><Clinical Trials><Cross-Priming><Cytolysis><Dendritic Cells><Dendritic cell activation><Development><Dose><Engineering><FDA approved><Gene Transcription><Generalized Growth><Generations><Genetic Transcription><Goals><Growth><HIGM1><Human><IFN><IFNAR><IFNAR1><IFNAR1 gene><IMD3><Immune><Immune checkpoint inhibitor><Immune mediated therapy><Immunes><Immunity><Immunologically Directed Therapy><Immunostimulatory drug><Immunotherapy><In Situ><Inflammatory><Injections><Innate Immunity><Interferons><Intracellular Communication and Signaling><KO mice><Knock-out Mice><Knockout Mice><Laboratory Study><Lead><Lung Neoplasms><Lung Tumor><Lysis><MGC9013><Malignant Cell><Malignant Melanoma><Malignant Neoplasm Therapy><Malignant Neoplasm Treatment><Malignant Neoplasms><Malignant Tumor><Malignant Tumor of the Lung><Malignant neoplasm of lung><Melanoma><Melanoma Tumor><Membrane><Memory><Mice><Mice Mammals><Modality><Modeling><Modern Man><Murine><Mus><NSCLC><NSCLC - Non-Small Cell Lung Cancer><Native Immunity><Natural Immunity><Non-Small Cell Lung Cancer><Non-Small-Cell Lung Carcinoma><Non-Specific Immunity><Nonspecific Immunity><Normal Cell><Null Mouse><Oncolytic viruses><Pathway interactions><Patients><Pb element><Phase><Pulmonary Cancer><Pulmonary Neoplasms><Pulmonary malignant Neoplasm><RNA Expression><Refractory><Research Resources><Resources><Signal Transduction><Signal Transduction Systems><Signaling><Solid><Solid Neoplasm><Solid Tumor><Stem Cell like><T cell receptor repertoire sequencing><T cell receptor sequencing><T cell response><T-B Cell Activating Molecule><T-Cell Activation><T-Cell gp39 Antigen><T-Cells><T-Lymphocyte><T8 Cells><T8 Lymphocytes><TCR repertoire sequencing><TCR sequencing><TCR-seq><TCRseq><TNF-Related Activation Protein><TNFRSF5><TNFRSF5 gene><Teff cell><Testing><Therapeutic><Tissue Growth><Toxic effect><Toxicities><Transcription><Tumor Cell><Tumor Immunity><Tumor Necrosis Factor Ligand Superfamily Member 5><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><Tumor growth in melanoma><Upregulation><Validation><Veiled Cells><Viral Activity><Viral Function><Viral Physiology><activate T cells><anti-cancer immunotherapy><anti-cancer therapy><anti-tumor immunity><anti-tumor response><anticancer immunotherapy><antitumor immunity><biological signal transduction><cancer cell><cancer immunity><cancer immunotherapy><cancer microenvironment><cancer therapy><cancer type><cancer-directed therapy><cell type><clinical development><conditionally replicating adenovirus><conditionally replicative adenovirus><developmental><draining lymph node><effector T cell><falls><first in man><first-in-human><gain of function><heavy metal Pb><heavy metal lead><immune activator><immune check point inhibitor><immune stimulatory agent><immune stimulatory drug><immune stimulatory therapeutic><immune therapeutic approach><immune therapeutic interventions><immune therapeutic regimens><immune therapeutic strategy><immune therapy><immune-based cancer therapies><immune-based therapies><immune-based treatments><immuno therapy><immunostimulatory agents><immunostimulatory biologics><immunotherapy for cancer><immunotherapy of cancer><improved><insight><loss of function><lung cancer><malignancy><membrane structure><migration><mouse model><murine model><neo-antigen><neo-epitopes><neoantigens><neoepitopes><neoplasm/cancer><neoplastic cell><novel><oncolytic adenovirus><ontogeny><p50><participant enrollment><pathway><patient enrollment><pre-clinical study><preclinical study><progenitor capacity><progenitor cell like><progenitor-like><programs><regional lymph node><response><stem cell characteristics><stem-like><stemness><synergism><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment><thymus derived lymphocyte><trafficking><tumor><tumor growth><tumor microenvironment><validations>
View Full Project Details on NIH Reporter
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Wendy M Kohrt

UNIVERSITY OF COLORADO DENVER, Aurora, CO

Good lead · 62/100
Large award
Very recent
Active award
Team-scale grant
$1,500,000
FY 2026

Project Title

Bioenergetic and Cardiometabolic Consequences of the Loss of Gonadal Function

Grant Number:

5U54AG062319-13

Activity Code:

U54

Mechanism:

Research Centers

Agency:

NIH

Start Date:

9/20/2012

End Date:

2/28/2029

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

The Colorado Specialized Center of Research Excellence (SCORE) on Sex Differences and Women’s Health is focused on Bioenergetic and Cardiometabolic Consequences of the Loss of Gonadal Function. The overarching scientific goal of the SCORE is to address gaps in knowledge of the impact of gonadal agin...

Research Terms

<Abdomen><Acceleration><Address><Advisory Committees><Aging><Aquadiol><Area><Autoregulation><Award><Benchmarking><Best Practice Analysis><Bioenergetics><Biological><Biometrics><Biometry><Biostatistics><COBRE><Career Mobility><Center of Biomedical Research Excellence><Centers of Research Excellence><Chronic Disease><Chronic Illness><Clinical><Clinical Sciences><Colorado><Communities><Curriculum><Diabetes Mellitus><Differences between sexes><Differs between sexes><Dimenformon><Diogyn><Diogynets><Disease><Disorder><Dysfunction><Education><Educational Activities><Educational Curriculum><Educational aspects><Elderly><Estrace><Estradiol><Estradiol-17 beta><Estradiol-17beta><Estraldine><Estrogen decline><Estrogens><Evaluation Research><Exercise><Faculty><Failure><Family><Fats><Fatty acid glycerol esters><Female><Female Health><Functional disorder><Goals><Gonadal Steroid Hormones><Grant><Health><History><Homeostasis><Institution><Interdisciplinary Research><Interdisciplinary Study><Intermediary Metabolism><Investigators><Knowledge><Kynurenine><L-Tryptophan><Leadership><Levotryptophan><Mediating><Medical><Menopause><Mentors><Metabolic><Metabolic Processes><Metabolism><Midlife women><Modeling><Multidisciplinary Collaboration><Multidisciplinary Research><Nutrition><Obesity><Osteoporosis><Ovarian><Ovocyclin><Ovocylin><P50 Mechanism><P50 Program><Pathway interactions><Physiological Homeostasis><Physiopathology><Pilot Projects><Position><Positioning Attribute><Postdoc><Postdoctoral Fellow><Process><Productivity><Program Development><Progynon><R-Series Research Projects><R01 Mechanism><R01 Program><Recording of previous events><Regulation><Research><Research Associate><Research Grants><Research Personnel><Research Project Grants><Research Projects><Research Resources><Researchers><Resources><Risk><Salaries><Scientist><Sex Differences><Sex Hormones><Sex Steroid Hormones><Sexual differences><Specialized Center><Task Forces><Testosterone><Therapeutic Estradiol><Therapeutic Estrogen><Therapeutic Testosterone><Time><Training><Training Activity><Training Programs><Trans-Testosterone><Translational Research><Translational Science><Tryptophan><Universities><Visit><Wages><Withdrawal><Woman><Women's Health><abdominal adiposity><abdominal fat><adiposity><advanced age><advisory team><aging process><benchmark><biologic><biological sex as a modifier><cardiac disease risk><cardiac disorder risk><cardiometabolic><cardiometabolism><career><career advancement><career development><career transition><chronic disorder><clinical translation><clinically translatable><conference><convention><corpulence><data management><decline in estrogen><declines in circulating testosterone><declining testosterone><decrease estrogen><decrease in estrogen><decreased levels of testosterone><decreases in testosterone><decreasing testosterone><deficiency in testosterone><diabetes><diminished testosterone><dimished estrogen><estrogen depletion><estrogen level decrease><estrogen loss><evaluation investigation><expectation><experience><female at midlife><female reproductive health><geriatric><gonad function><gonadal function><gonadal steroids><heart disease risk><heart disorder risk><histories><improved><innovate><innovation><innovative><interest><investigate evaluation><investigator training><later in life><later life><lesson plans><low circulating testosterone><low levels of testosterone><lower testosterone><male><meeting><meetings><men><mid life><mid-life><mid-life female><middle age><middle aged><middle-aged female><middle-aged women><midlife><multidisciplinary><next generation><novel><pathophysiology><pathway><pilot study><post-doc><post-doctoral><post-doctoral trainee><pre-clinical><preclinical><prevent><preventing><programs><reduced estrogen><reduced testosterone><reduction in testosterone><reproductive health among females><reproductive health among women><reproductive health in females><reproductive health in women><research associates><senior citizen><sex as a biological factor><sex as a biological measure><sex as a biological risk factor><sex as a biological variable><sex as a biological variance><sex as a biologically significant variable><sex as a fundamental variable><sex based differences><sex steroid><sex-dependent differences><sex-related differences><sex-specific differences><study evaluation><summit><survey evaluation><symposia><symposium><synergism><testosterone decline><testosterone deficiency><testosterone insufficiency><testosterone loss><training module><translation research><translational investigation><translational pipeline><translational spectrum><women at midlife><women in midlife><women's reproductive health><♀><♂>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Sylvia E Rosas

BOSTON MEDICAL CENTER, BOSTON, MA

Good lead · 62/100
Likely hiring
Above-average budget
Active award
Team-scale grant
$799,998
FY 2025

Project Title

Boston Chronic Kidney Disease Research Biopsy Center

Grant Number:

5U01DK133092-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2022

End Date:

6/30/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Chronic kidney disease (CKD) affects 37 million Americans, costs tens of billions of dollars annually, and can lead to kidney failure, cardiovascular disease (CVD), and early mortality. CKD is not a single entity but rather a heterogeneous condition with a wide spectrum of underlying...

Research Terms

<21+ years old><Academic Medical Centers><Active Follow-up><Adult><Adult Human><Affect><Agreement><Amendment><American><Animal Model><Animal Models and Related Studies><Awareness><Biopsy><Biopsy Sample><Biopsy Specimen><Body Tissues><Boston><Brittle Diabetes Mellitus><Budgets><Cardiovascular Diseases><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Clinic><Clinical><Collection><Communities><Consent Documents><Consent Forms><Development><Diabetes Mellitus><Diabetic Kidney Disease><Diabetic Nephropathy><Disparity population><Dysfunction><ESKD><ESRD><Education><Educational aspects><Employment><End stage renal failure><End-Stage Kidney Disease><End-Stage Renal Disease><Endocrinologist><Endocrinology><Enrollment><Ensure><Ethics><Exclusion Criteria><Functional disorder><Geography><Glomerular Filtration Rate><Hospitals><Human><Hypertension><IDDM><Individual><Informed Consent Documents><Informed Consent Forms><Infrastructure><Insulin-Dependent Diabetes Mellitus><Interdisciplinary Research><Interdisciplinary Study><Investigation><Investigators><Israel><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Kidney><Kidney Diseases><Kidney Failure><Kidney Insufficiency><Kidney Urinary System><Knowledge><Laboratories><Leadership><Literature><Long-term cohort study><Longitudinal cohort study><Medical center><Metabolism and Endocrinology><Modern Man><Molecular><Multidisciplinary Collaboration><Multidisciplinary Research><Nephrology><Nephropathy><P50 Mechanism><P50 Program><Participant><Pathologic><Pathology><Patients><Phase><PhenX Toolkit><Phenotypes and eXposures Toolkit><Phenx><Physiopathology><Population><Population Heterogeneity><Primary Care Physician><Proteome><Protocol><Protocols documentation><Public Health><Radial><Radius><Renal Cell><Renal Disease><Renal Failure><Renal Insufficiency><Renal function><Research><Research Personnel><Researchers><Risk><Role><Safety><Science><Site><Socioeconomically disadvantaged><Spatial Distribution><Specialized Center><Sudden-Onset Diabetes Mellitus><T1 DM><T1 diabetes><T1D><T1DM><Techniques><Tissue Sample><Tissue atlas><Tissues><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><University Medical Centers><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Vulnerable Populations><Woman><active followup><adjudication><adjudicative process and procedure><adulthood><cardiovascular disorder><chronic kidney disease><clinical research site><clinical site><community advisory board><community advisory committee><community advisory panel><cost><developmental><diabetes><disadvantaged group><disadvantaged individual><disadvantaged people><disadvantaged population><disadvantaged subgroup><disparities across groups><disparity across subgroups><disparity among groups><disparity among subgroups><disparity between groups><disparity between subgroups><diverse populations><eligible participant><enroll><ethical><ethnic minority><experience><follow up><follow-up><followed up><followup><global gene expression><global transcription profile><group disparity><group inequality><group inequity><heterogeneous population><high blood pressure><high risk><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><improved><inclusion criteria><inequalities among populations><inequalities between populations><inequalities in populations><inequality across populations><inequality among groups><inequality between groups><inequality in groups><inequities among populations><inequities between populations><inequities in populations><inequity across groups><inequity across populations><inequity between groups><inequity in groups><insight><insulin dependent diabetes><insulin dependent type 1><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><kidney biopsy><kidney cell><kidney disorder><kidney function><literacy><member><metabolome><metabonome><model of animal><molecular pathology><mortality><new approaches><novel><novel approaches><novel strategies><novel strategy><participant engagement><participant enrollment><pathophysiology><patient engagement><patient enrollment><patient population><population diversity><population inequality><population inequity><precision medicine><precision-based medicine><primary care clinic><protocol development><racial minority><recruit><renal><renal biopsy><renal disorder><retention rate><retention strategy><safety net><social health determinants><social role><socio-economic disadvantage><socio-economically disadvantaged><socio-economically underprivileged><socioeconomic disadvantage><socioeconomically underprivileged><subgroup disparity><tertiary care><transcriptome><type I diabetes><type one diabetes><unequal group><unequal population><vulnerable group><vulnerable individual><vulnerable people>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Sushrut S. Waikar

BOSTON MEDICAL CENTER, BOSTON, MA

Good lead · 62/100
Likely hiring
Above-average budget
Active award
Team-scale grant
$799,998
FY 2025

Project Title

Boston Chronic Kidney Disease Research Biopsy Center

Grant Number:

5U01DK133092-04

Activity Code:

U01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2022

End Date:

6/30/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Chronic kidney disease (CKD) affects 37 million Americans, costs tens of billions of dollars annually, and can lead to kidney failure, cardiovascular disease (CVD), and early mortality. CKD is not a single entity but rather a heterogeneous condition with a wide spectrum of underlying...

Research Terms

<21+ years old><Academic Medical Centers><Active Follow-up><Adult><Adult Human><Affect><Agreement><Amendment><American><Animal Model><Animal Models and Related Studies><Awareness><Biopsy><Biopsy Sample><Biopsy Specimen><Body Tissues><Boston><Brittle Diabetes Mellitus><Budgets><Cardiovascular Diseases><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Clinic><Clinical><Collection><Communities><Consent Documents><Consent Forms><Development><Diabetes Mellitus><Diabetic Kidney Disease><Diabetic Nephropathy><Disparity population><Dysfunction><ESKD><ESRD><Education><Educational aspects><Employment><End stage renal failure><End-Stage Kidney Disease><End-Stage Renal Disease><Endocrinologist><Endocrinology><Enrollment><Ensure><Ethics><Exclusion Criteria><Functional disorder><Geography><Glomerular Filtration Rate><Hospitals><Human><Hypertension><IDDM><Individual><Informed Consent Documents><Informed Consent Forms><Infrastructure><Insulin-Dependent Diabetes Mellitus><Interdisciplinary Research><Interdisciplinary Study><Investigation><Investigators><Israel><Juvenile-Onset Diabetes Mellitus><Ketosis-Prone Diabetes Mellitus><Kidney><Kidney Diseases><Kidney Failure><Kidney Insufficiency><Kidney Urinary System><Knowledge><Laboratories><Leadership><Literature><Long-term cohort study><Longitudinal cohort study><Medical center><Metabolism and Endocrinology><Modern Man><Molecular><Multidisciplinary Collaboration><Multidisciplinary Research><Nephrology><Nephropathy><P50 Mechanism><P50 Program><Participant><Pathologic><Pathology><Patients><Phase><PhenX Toolkit><Phenotypes and eXposures Toolkit><Phenx><Physiopathology><Population><Population Heterogeneity><Primary Care Physician><Proteome><Protocol><Protocols documentation><Public Health><Radial><Radius><Renal Cell><Renal Disease><Renal Failure><Renal Insufficiency><Renal function><Research><Research Personnel><Researchers><Risk><Role><Safety><Science><Site><Socioeconomically disadvantaged><Spatial Distribution><Specialized Center><Sudden-Onset Diabetes Mellitus><T1 DM><T1 diabetes><T1D><T1DM><Techniques><Tissue Sample><Tissue atlas><Tissues><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><University Medical Centers><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Vulnerable Populations><Woman><active followup><adjudication><adjudicative process and procedure><adulthood><cardiovascular disorder><chronic kidney disease><clinical research site><clinical site><community advisory board><community advisory committee><community advisory panel><cost><developmental><diabetes><disadvantaged group><disadvantaged individual><disadvantaged people><disadvantaged population><disadvantaged subgroup><disparities across groups><disparity across subgroups><disparity among groups><disparity among subgroups><disparity between groups><disparity between subgroups><diverse populations><eligible participant><enroll><ethical><ethnic minority><experience><follow up><follow-up><followed up><followup><global gene expression><global transcription profile><group disparity><group inequality><group inequity><heterogeneous population><high blood pressure><high risk><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><improved><inclusion criteria><inequalities among populations><inequalities between populations><inequalities in populations><inequality across populations><inequality among groups><inequality between groups><inequality in groups><inequities among populations><inequities between populations><inequities in populations><inequity across groups><inequity across populations><inequity between groups><inequity in groups><insight><insulin dependent diabetes><insulin dependent type 1><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><kidney biopsy><kidney cell><kidney disorder><kidney function><literacy><member><metabolome><metabonome><model of animal><molecular pathology><mortality><new approaches><novel><novel approaches><novel strategies><novel strategy><participant engagement><participant enrollment><pathophysiology><patient engagement><patient enrollment><patient population><population diversity><population inequality><population inequity><precision medicine><precision-based medicine><primary care clinic><protocol development><racial minority><recruit><renal><renal biopsy><renal disorder><retention rate><retention strategy><safety net><social health determinants><social role><socio-economic disadvantage><socio-economically disadvantaged><socio-economically underprivileged><socioeconomic disadvantage><socioeconomically underprivileged><subgroup disparity><tertiary care><transcriptome><type I diabetes><type one diabetes><unequal group><unequal population><vulnerable group><vulnerable individual><vulnerable people>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Fernanda Laezza

BAYLOR COLLEGE OF MEDICINE, HOUSTON, TX

Good lead · 62/100
Likely hiring
Above-average budget
Active award
Team-scale grant
$717,392
FY 2025

Project Title

Gulf Coast Center for Precision Environmental Health

Grant Number:

5P30ES030285-07

Activity Code:

P30

Mechanism:

Research Centers

Agency:

NIH

Start Date:

5/15/2019

End Date:

5/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

The Texas Medical Center (TMC), encompassing the top research-intensive institutions in the Gulf Coast Region, has emerged as an Environmental Health Sciences (EHS) research powerhouse, driven by the establishment in 2019 of the Gulf Coast Center for Precision Environmental Health (GC-CPEH). The Str...

Research Terms

<Acceleration><Affect><Area><Career Mobility><Collaborations><Communication><Communities><Core Facility><Data Science><Disasters><Discipline><Disease><Disorder><Environment><Environmental Health><Environmental Health Science><Environmental Science><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Event><Faculty><Fostering><Funding><Genetic><Genome><Goals><Grant><Health><Health Promotion><Health Sciences><Home><Human><Individual><Institution><Intervention><Investigators><Knowledge><Link><Medical center><Medicine><Modern Man><NIEHS><National Institute of Environmental Health Sciences><Pilot Projects><Program Development><Publications><Research><Research Personnel><Research Resources><Research Support><Researchers><Resources><Salutogenesis><Scientific Publication><Services><Sight><Strategic vision><Superfund><Technology><Texas><Training><Translational Research><Translational Science><Translations><Universities><Veterans><Vision><Work><base><bases><career advancement><career development><career transition><catalyst><college><collegiate><community empowerment><community engagement><disease risk><disorder risk><engagement with communities><epigenetically><epigenome><experience><extreme weather><gulf coast><health science research><homes><improved><inter-institutional><member><next generation><pilot study><prevent><preventing><programs><promoting health><response><translation><translation research><translational investigation><visual function>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Cheryl L. Walker

BAYLOR COLLEGE OF MEDICINE, HOUSTON, TX

Good lead · 62/100
Likely hiring
Above-average budget
Active award
Team-scale grant
$717,392
FY 2025

Project Title

Gulf Coast Center for Precision Environmental Health

Grant Number:

5P30ES030285-07

Activity Code:

P30

Mechanism:

Research Centers

Agency:

NIH

Start Date:

5/15/2019

End Date:

5/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

The Texas Medical Center (TMC), encompassing the top research-intensive institutions in the Gulf Coast Region, has emerged as an Environmental Health Sciences (EHS) research powerhouse, driven by the establishment in 2019 of the Gulf Coast Center for Precision Environmental Health (GC-CPEH). The Str...

Research Terms

<Acceleration><Affect><Area><Career Mobility><Collaborations><Communication><Communities><Core Facility><Data Science><Disasters><Discipline><Disease><Disorder><Environment><Environmental Health><Environmental Health Science><Environmental Science><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Event><Faculty><Fostering><Funding><Genetic><Genome><Goals><Grant><Health><Health Promotion><Health Sciences><Home><Human><Individual><Institution><Intervention><Investigators><Knowledge><Link><Medical center><Medicine><Modern Man><NIEHS><National Institute of Environmental Health Sciences><Pilot Projects><Program Development><Publications><Research><Research Personnel><Research Resources><Research Support><Researchers><Resources><Salutogenesis><Scientific Publication><Services><Sight><Strategic vision><Superfund><Technology><Texas><Training><Translational Research><Translational Science><Translations><Universities><Veterans><Vision><Work><base><bases><career advancement><career development><career transition><catalyst><college><collegiate><community empowerment><community engagement><disease risk><disorder risk><engagement with communities><epigenetically><epigenome><experience><extreme weather><gulf coast><health science research><homes><improved><inter-institutional><member><next generation><pilot study><prevent><preventing><programs><promoting health><response><translation><translation research><translational investigation><visual function>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

KRISTI D. GRAVES

GEORGETOWN UNIVERSITY, WASHINGTON, DC

Good lead · 62/100
Likely hiring
Above-average budget
Active award
Team-scale grant
$701,998
FY 2025

Project Title

Development of Investigators Supporting Community Outreach and Value of Engagement in health disparities Research (DISCOVER)

Grant Number:

5P50MD019487-02

Activity Code:

P50

Mechanism:

Research Centers

Agency:

NIH

Start Date:

8/10/2024

End Date:

2/28/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT Our proposed P50 Center of Excellence in Investigator Development and Community Engagement – Development of Investigators Supporting Community Outreach and Value of Engagement in health disparities Research, DISCOVER, will establish the organizational infrastructure to deve...

Research Terms

<Academic Medical Centers><Address><Aging><Apoplexy><Area><Award><Awareness><Black><Black race><Brain Vascular Accident><Cancer Burden><Cancers><Capital><Career Development Awards><Career Development Awards and Programs><Career Development Programs K-Series><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Clinical><Clinical Investigator><Clinical and Translational Science Awards><Communication><Communities><Community Outreach><Competence><Comprehensive Cancer Center><Country><Curriculum><D.C. Washington><DC Washington><Decrease health disparities><Dedications><Development><Development and Research><District of Columbia><Educational Curriculum><Elements><Evaluation><Fostering><Funding><Gestation><Goals><Grant><Health><Health Disparities Research><Health disparities related research><Health disparity mitigation><Health disparity reduction><Hispanic><Infant Health><Information Dissemination><Infrastructure><Institution><Investigators><K-Awards><K-Series Research Career Programs><K12><K12 Award><K12 Mechanism><K12 Program><Knowledge><Latino><Leadership><Life Expectancy><Lower health disparities><Malignant Neoplasms><Malignant Tumor><Maternal Health><Mentored Clinical Scientist Development Program><Mentors><Mitigate health disparities><Modeling><Morbidity><Morbidity - disease rate><National Cancer Burden><Outcome><Outcomes Research><Position><Positioning Attribute><Postdoc><Postdoctoral Fellow><Pregnancy><R & D><R&D><Reduce health disparities><Research><Research Associate><Research Career Program><Research Methodology><Research Methods><Research Personnel><Research Resources><Research Training><Researchers><Resources><Stroke><TL1><TNF Ligand-Related Molecule 1><TNF15><TNFSF15><TNFSF15 gene><Training><Tumor Necrosis Factor Ligand Superfamily Member 15><University Medical Centers><VEGI><Vascular Endothelial Growth Inhibitor><Washington><Workforce Development><brain attack><cancer disparity><cancer health disparity><cancer-related health disparity><career><catalyst><cerebral vascular accident><cerebrovascular accident><cohort><community academic collaboration><community academic partnership><community academic research partnership><community advisory board><community advisory committee><community advisory panel><community engagement><community partners><community university partnership><community-based partners><developmental><disparity in cancer><disparity in health><dissemination of results><early-career faculty><engagement with communities><health disparities science><health disparity><improved><improved outcome><innovate><innovation><innovative><lesson plans><malignancy><member><mortality><neoplasm/cancer><new approaches><next generation><novel approaches><novel strategies><novel strategy><peer><peer coaching><peer instruction><peer led team learning><peer mentoring><peer teaching><population health><post-doc><post-doctoral><post-doctoral trainee><post-doctoral training><pre-doc><pre-doctoral><programs><research and development><research and methods><research associates><skills><social health determinants><stroked><strokes><structural determinants><structural factors>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Caleb McKinney

GEORGETOWN UNIVERSITY, WASHINGTON, DC

Good lead · 62/100
Likely hiring
Above-average budget
Active award
Team-scale grant
$701,998
FY 2025

Project Title

Development of Investigators Supporting Community Outreach and Value of Engagement in health disparities Research (DISCOVER)

Grant Number:

5P50MD019487-02

Activity Code:

P50

Mechanism:

Research Centers

Agency:

NIH

Start Date:

8/10/2024

End Date:

2/28/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT Our proposed P50 Center of Excellence in Investigator Development and Community Engagement – Development of Investigators Supporting Community Outreach and Value of Engagement in health disparities Research, DISCOVER, will establish the organizational infrastructure to deve...

Research Terms

<Academic Medical Centers><Address><Aging><Apoplexy><Area><Award><Awareness><Black><Black race><Brain Vascular Accident><Cancer Burden><Cancers><Capital><Career Development Awards><Career Development Awards and Programs><Career Development Programs K-Series><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Clinical><Clinical Investigator><Clinical and Translational Science Awards><Communication><Communities><Community Outreach><Competence><Comprehensive Cancer Center><Country><Curriculum><D.C. Washington><DC Washington><Decrease health disparities><Dedications><Development><Development and Research><District of Columbia><Educational Curriculum><Elements><Evaluation><Fostering><Funding><Gestation><Goals><Grant><Health><Health Disparities Research><Health disparities related research><Health disparity mitigation><Health disparity reduction><Hispanic><Infant Health><Information Dissemination><Infrastructure><Institution><Investigators><K-Awards><K-Series Research Career Programs><K12><K12 Award><K12 Mechanism><K12 Program><Knowledge><Latino><Leadership><Life Expectancy><Lower health disparities><Malignant Neoplasms><Malignant Tumor><Maternal Health><Mentored Clinical Scientist Development Program><Mentors><Mitigate health disparities><Modeling><Morbidity><Morbidity - disease rate><National Cancer Burden><Outcome><Outcomes Research><Position><Positioning Attribute><Postdoc><Postdoctoral Fellow><Pregnancy><R & D><R&D><Reduce health disparities><Research><Research Associate><Research Career Program><Research Methodology><Research Methods><Research Personnel><Research Resources><Research Training><Researchers><Resources><Stroke><TL1><TNF Ligand-Related Molecule 1><TNF15><TNFSF15><TNFSF15 gene><Training><Tumor Necrosis Factor Ligand Superfamily Member 15><University Medical Centers><VEGI><Vascular Endothelial Growth Inhibitor><Washington><Workforce Development><brain attack><cancer disparity><cancer health disparity><cancer-related health disparity><career><catalyst><cerebral vascular accident><cerebrovascular accident><cohort><community academic collaboration><community academic partnership><community academic research partnership><community advisory board><community advisory committee><community advisory panel><community engagement><community partners><community university partnership><community-based partners><developmental><disparity in cancer><disparity in health><dissemination of results><early-career faculty><engagement with communities><health disparities science><health disparity><improved><improved outcome><innovate><innovation><innovative><lesson plans><malignancy><member><mortality><neoplasm/cancer><new approaches><next generation><novel approaches><novel strategies><novel strategy><peer><peer coaching><peer instruction><peer led team learning><peer mentoring><peer teaching><population health><post-doc><post-doctoral><post-doctoral trainee><post-doctoral training><pre-doc><pre-doctoral><programs><research and development><research and methods><research associates><skills><social health determinants><stroked><strokes><structural determinants><structural factors>
View Full Project Details on NIH Reporter
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Michelle Roett

GEORGETOWN UNIVERSITY, WASHINGTON, DC

Good lead · 62/100
Likely hiring
Above-average budget
Active award
Team-scale grant
$701,998
FY 2025

Project Title

Development of Investigators Supporting Community Outreach and Value of Engagement in health disparities Research (DISCOVER)

Grant Number:

5P50MD019487-02

Activity Code:

P50

Mechanism:

Research Centers

Agency:

NIH

Start Date:

8/10/2024

End Date:

2/28/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT Our proposed P50 Center of Excellence in Investigator Development and Community Engagement – Development of Investigators Supporting Community Outreach and Value of Engagement in health disparities Research, DISCOVER, will establish the organizational infrastructure to deve...

Research Terms

<Academic Medical Centers><Address><Aging><Apoplexy><Area><Award><Awareness><Black><Black race><Brain Vascular Accident><Cancer Burden><Cancers><Capital><Career Development Awards><Career Development Awards and Programs><Career Development Programs K-Series><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Clinical><Clinical Investigator><Clinical and Translational Science Awards><Communication><Communities><Community Outreach><Competence><Comprehensive Cancer Center><Country><Curriculum><D.C. Washington><DC Washington><Decrease health disparities><Dedications><Development><Development and Research><District of Columbia><Educational Curriculum><Elements><Evaluation><Fostering><Funding><Gestation><Goals><Grant><Health><Health Disparities Research><Health disparities related research><Health disparity mitigation><Health disparity reduction><Hispanic><Infant Health><Information Dissemination><Infrastructure><Institution><Investigators><K-Awards><K-Series Research Career Programs><K12><K12 Award><K12 Mechanism><K12 Program><Knowledge><Latino><Leadership><Life Expectancy><Lower health disparities><Malignant Neoplasms><Malignant Tumor><Maternal Health><Mentored Clinical Scientist Development Program><Mentors><Mitigate health disparities><Modeling><Morbidity><Morbidity - disease rate><National Cancer Burden><Outcome><Outcomes Research><Position><Positioning Attribute><Postdoc><Postdoctoral Fellow><Pregnancy><R & D><R&D><Reduce health disparities><Research><Research Associate><Research Career Program><Research Methodology><Research Methods><Research Personnel><Research Resources><Research Training><Researchers><Resources><Stroke><TL1><TNF Ligand-Related Molecule 1><TNF15><TNFSF15><TNFSF15 gene><Training><Tumor Necrosis Factor Ligand Superfamily Member 15><University Medical Centers><VEGI><Vascular Endothelial Growth Inhibitor><Washington><Workforce Development><brain attack><cancer disparity><cancer health disparity><cancer-related health disparity><career><catalyst><cerebral vascular accident><cerebrovascular accident><cohort><community academic collaboration><community academic partnership><community academic research partnership><community advisory board><community advisory committee><community advisory panel><community engagement><community partners><community university partnership><community-based partners><developmental><disparity in cancer><disparity in health><dissemination of results><early-career faculty><engagement with communities><health disparities science><health disparity><improved><improved outcome><innovate><innovation><innovative><lesson plans><malignancy><member><mortality><neoplasm/cancer><new approaches><next generation><novel approaches><novel strategies><novel strategy><peer><peer coaching><peer instruction><peer led team learning><peer mentoring><peer teaching><population health><post-doc><post-doctoral><post-doctoral trainee><post-doctoral training><pre-doc><pre-doctoral><programs><research and development><research and methods><research associates><skills><social health determinants><stroked><strokes><structural determinants><structural factors>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Mandy L Ford

EMORY UNIVERSITY, ATLANTA, GA

Good lead · 60/100
Likely hiring
Large award
Active award
$2,481,496
FY 2025

Project Title

CD11b: A Novel Alternate Receptor for CD154 during Alloimmunity

Grant Number:

2R01AI152516-06

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/17/2020

End Date:

6/30/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Summary Blockade of CD154 during transplantation is a highly effective means of inhibiting alloreactive T cell responses and inducing long-term survival of allografts, but clinical translation of this pathway has been circuitous and fraught with challenges. However, CD40 blockers have shown consiste...

Research Terms

<Allografting><Anti-CD40><Antigens><Automobile Driving><Binding><Blood Platelets><Blood monocyte><Bp50><CD11b><CD154><CD28><CD28 gene><CD40><CD40L><CD40LG><CD8 Cell><CD8 T cells><CD8 lymphocyte><CD8+ T cell><CD8+ T-Lymphocyte><CD8-Positive Lymphocytes><CD8-Positive T-Lymphocytes><CDW40><CR3A><Cell Body><Cell Communication and Signaling><Cell Isolation><Cell Segregation><Cell Separation><Cell Separation Technology><Cell Signaling><Cells><Clinical><Clinical Treatment Moab><Clinical Trials><Co-Stimulator><Costimulator><Data><Epidermal Thymocyte Activating Factor><FDA approved><Failure><Funding><Grant><Hemostatic Agents><Hemostatics><Human><IL-2><IL2 Protein><ITGAM><ITGAM gene><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><Immunotherapeutic agent><In Vitro><Inferior><Infiltration><Inflammation><Interleukin 2><Interleukin 2 Precursor><Interleukin II><Interleukin-2><Interleukine 2><Interleukine 2 Precursor><Interleukine II><Intracellular Communication and Signaling><Kidney Grafting><Kidney Transplantation><Kidney Transplants><Ligands><Lymphocyte Mitogenic Factor><MAC1A><MGC9013><MO1A><Macrophage><Marrow monocyte><Marrow platelet><Meta-Analysis><Methods><Mice><Mice Mammals><Mitogenic Factor><Modern Man><Molecular><Molecular Interaction><Monoclonal Antibodies><Murine><Mus><Mφ><Pathway interactions><Patients><Platelets><Play><Population><Preclinical data><Proliferating><Publishing><Reagent><Receptor Protein><Renal Grafting><Renal Transplantation><Renal Transplants><Reporting><Residual><Residual state><Resistance><Role><Side><Signal Transduction><Signal Transduction Systems><Signaling><T cell growth factor><T cell response><T-Cell Growth Factor><T-Cell Stimulating Factor><T-Cell Subsets><T-Cells><T-Lymphocyte><T-Lymphocyte Subsets><T44><T8 Cells><T8 Lymphocytes><TNFRSF5><TNFRSF5 gene><TNFSF5><TNFSF5 gene><TRAP Gene><Tacrolimus><Testing><Therapeutic><Thrombocytes><Thromboembolism><Thymocyte Stimulating Factor><Transplant Recipients><Transplant immunology><Transplantation><Transplantation Immunology><Transplantation Tolerance><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><alloimmunity><biological signal transduction><cell sorting><clinical relevance><clinical translation><clinically relevant><clinically translatable><crosslink><driving><early clinical trial><early phase clinical trial><experience><experiment><experimental research><experimental study><experiments><human data><immune drugs><immune suppression><immune suppressive activity><immune suppressive function><immune-based therapeutics><immunogen><immunologic therapeutics><immunosuppressive activity><immunosuppressive function><immunosuppressive response><immunotherapeutics><immunotherapy agent><improved><innovate><innovation><innovative><isoimmunity><kidney tx><mAbs><monoclonal Abs><monocyte><mouse model><murine model><nano particle><nano-sized particle><nanoparticle><nanoparticle therapy><nanosized particle><nanotherapeutic><novel><p50><pathway><pre-clinical study><preclinical findings><preclinical information><preclinical study><primary end point><primary endpoint><rational design><receptor><recruit><resistant><scRNA sequencing><scRNA-seq><single cell RNA-seq><single cell RNAseq><single cell analysis><single cell expression profiling><single cell transcriptomic profiling><single-cell RNA sequencing><social role><synergism><therapeutic nanoparticles><therapeutic target><thymus derived lymphocyte><transplant><transplant model><transplant patient>
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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Suvarna Alladi

EMORY UNIVERSITY, ATLANTA, GA

Good lead · 60/100
Likely hiring
Large award
Active award
$2,442,538
FY 2025

Project Title

P-CARRS-BRAIN: Multi-domain (genetic, socio-behavioral, vascular) risk factors and prediction of Alzheimer’s Disease continuum in South Asians in India

Grant Number:

5R01AG089759-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2024

End Date:

8/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY/ABSTRACT While it is widely acknowledged that Alzheimer’s disease and related dementias (AD/ADRD) have an extended preclinical phase, there are sparse data on the cognitive and pathobiological changes in middle-ages, a critical window for preventative intervention in people likely to...

Research Terms

<21+ years old><AD dementia><AD pathology><AD related dementia><ADRD><AI Augmented><AI assisted><AI driven><AI enhanced><AI integrated><AI powered><Active Follow-up><Address><Adult><Adult Human><Age><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's biomarker><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease biological marker><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease pathology><Alzheimer's disease related dementia><Alzheimer's pathology><Alzheimers Dementia><Alzheimer’s biological marker><Alzheimer’s disease biomarker><Amentia><Apoplexy><Arteriosclerotic Dementia><Artificial Intelligence enhanced><Asian group><Asian individual><Asian people><Asian population><Asians><Assessment instrument><Assessment tool><Astroprotein><Augmented by AI><Augmented by the AI><Augmented with AI><Augmented with the AI><Behavioral><Biological><Biological Markers><Blood Plasma><Blood Vessels><Brain><Brain Nervous System><Brain Vascular Accident><Causality><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Classification><Clinical><Cognition><Cognitive><Collection><Complex><Data><Data Management and Analysis Core><Data Management and Statistical Analysis Core><Data Management and Statistical Core><Dementia><Detection><Diabetes Mellitus><Diagnosis><Digital biomarker><Disease><Disorder><Dyslipidemias><Early Diagnosis><Encephalon><Enrollment><Epidemic><Epidemiology><Etiology><European><Exhibits><Female><Funding><GFA-Protein><GFAP><GWA study><GWAS><Genetic><Genetic Risk><Genomics><Genotype><Glial Fibrillary Acid Protein><Glial Fibrillary Acidic Protein><Glial Intermediate Filament Protein><Goals><Hypertension><Image><India><Individual><Infrastructure><Knowledge><Language><Lead><Life><Life Cycle><Life Cycle Stages><Life Style><Lifestyle><Linguistic><Linguistics><Link><Longitudinal Studies><MR Imaging><MR Tomography><MRI><MRIs><Machine Learning><Magnetic Resonance Imaging><Measurement><Measures><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Metabolic><Myocardium><NHLBI><NMR Imaging><NMR Tomography><National Heart, Lung, and Blood Institute><Natural History><Neuropsychologies><Neuropsychology><Nuclear Magnetic Resonance Imaging><Organ><Outcome><Participant><Pathway interactions><Pattern><Pb element><Persons><Phase><Phenotype><Plasma><Plasma Serum><Population><Predicting Risk><Predisposition><Preventative intervention><Prevention><Primary Senile Degenerative Dementia><Protocol><Protocols documentation><Research><Reticuloendothelial System, Serum, Plasma><Retina><Risk><Risk Factors><Sampling><Sleep><Social Behavior><South Asian><Span 20><Spectroscopy><Spectrum Analyses><Spectrum Analysis><Standardization><Statistical Methods><Stress><Stroke><Susceptibility><System><Systematics><Therapeutic><Vascular Cognitive Impairment><Vascular Dementia><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Zeugmatography><accelerated aging><accelerated biological age><accelerated biological aging><active followup><adulthood><age acceleration><aged><aged group><aged groups><aged individual><aged individuals><aged people><aged person><aged persons><aged population><aged populations><ages><aging population><artificial intelligence assisted><artificial intelligence augmented><artificial intelligence driven><artificial intelligence integrated><artificial intelligence powered><bio-markers><biobank><biologic><biologic marker><biomarker><biorepository><brain MR imaging><brain MRI><brain attack><brain magnetic resonance imaging><cardiac muscle><cardiometabolic><cardiometabolism><causation><cerebral MR imaging><cerebral MRI><cerebral magnetic resonance imaging><cerebral vascular accident><cerebrovascular accident><cerebrovascular contribution to cognitive impairment><cerebrovascular contributions to cognitive dysfunction><cerebrovascular contributions to dementia><cognitive change><cohort><computer based prediction><dementia risk><diabetes><digital><digital cognitive assessment><digital cognitive test><digital marker><disease causation><early detection><early onset><enhanced with AI><enhanced with Artificial Intelligence><enroll><entire genome><epidemiologic><epidemiological><experience><family structure><follow up><follow-up><followed up><followup><forecasting risk><full genome><gene locus><genetic locus><genome sequencing><genome wide association><genome wide association scan><genome wide association study><genomewide association scan><genomewide association study><genomic location><genomic locus><heart muscle><heavy metal Pb><heavy metal lead><high blood pressure><high dimensional data><high risk><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><imaging><intervention for prevention><late in life><late life><learning network><life course><literate><long-term study><longitudinal design><longitudinal experimental design><longitudinal outcome studies><longitudinal research design><longitudinal study design><machine based learning><machine learning based prediction model><machine learning based predictive model><machine learning prediction><machine learning prediction model><malleable risk><mid life><mid-life><middle age><middle aged><midlife><mild cognitive disorder><mild cognitive impairment><modifiable risk><multi-modal data><multi-modal datasets><multi-modality><multidimensional data><multidimensional datasets><multimodal data><multimodal datasets><multimodality><neural imaging><neuro-imaging><neuroimaging><neuroimaging biomarker><neuroimaging marker><neurological imaging><neuropsychologic><new marker><novel><novel biomarker><novel marker><pathway><phenotypic data><pollutant><population aging><population based><pre-clinical><preclinical><predict risk><predict risks><predicted risk><predicted risks><predicting risks><predictive modeling><predictive risk><predictive tools><predicts risk><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><primary degenerative dementia><retinal imaging><risk factor for dementia><risk for dementia><risk prediction><risk predictions><senile dementia of the Alzheimer type><social culture><social structural><social structure><socio-cultural><socio-demographics><socio-structural><sociobehavior><sociobehavioral><sociocultural><sociodemographics><sociostructural><statistic methods><stroked><strokes><vascular><vascular and cognitive impairment><vascular cognition impairment><vascular cognitive decline><vascular cognitive disease><vascular cognitive disorder><vascular cognitive dysfunction><vascular contributions in dementia><vascular contributions to cognitive decline><vascular contributions to cognitive impairment><vascular contributions to dementia><vascular disease and impaired cognition><vascular dysfunction resulting in cognitive decline><vascular related cognitive decline><vascular related cognitive impairment><vascular related dementia><whole genome><whole genome association analysis><whole genome association study><younger age><♀>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

ALLAN I LEVEY

EMORY UNIVERSITY, ATLANTA, GA

Good lead · 60/100
Likely hiring
Large award
Active award
$2,442,538
FY 2025

Project Title

P-CARRS-BRAIN: Multi-domain (genetic, socio-behavioral, vascular) risk factors and prediction of Alzheimer’s Disease continuum in South Asians in India

Grant Number:

5R01AG089759-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2024

End Date:

8/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY/ABSTRACT While it is widely acknowledged that Alzheimer’s disease and related dementias (AD/ADRD) have an extended preclinical phase, there are sparse data on the cognitive and pathobiological changes in middle-ages, a critical window for preventative intervention in people likely to...

Research Terms

<21+ years old><AD dementia><AD pathology><AD related dementia><ADRD><AI Augmented><AI assisted><AI driven><AI enhanced><AI integrated><AI powered><Active Follow-up><Address><Adult><Adult Human><Age><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's biomarker><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease biological marker><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease pathology><Alzheimer's disease related dementia><Alzheimer's pathology><Alzheimers Dementia><Alzheimer’s biological marker><Alzheimer’s disease biomarker><Amentia><Apoplexy><Arteriosclerotic Dementia><Artificial Intelligence enhanced><Asian group><Asian individual><Asian people><Asian population><Asians><Assessment instrument><Assessment tool><Astroprotein><Augmented by AI><Augmented by the AI><Augmented with AI><Augmented with the AI><Behavioral><Biological><Biological Markers><Blood Plasma><Blood Vessels><Brain><Brain Nervous System><Brain Vascular Accident><Causality><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Classification><Clinical><Cognition><Cognitive><Collection><Complex><Data><Data Management and Analysis Core><Data Management and Statistical Analysis Core><Data Management and Statistical Core><Dementia><Detection><Diabetes Mellitus><Diagnosis><Digital biomarker><Disease><Disorder><Dyslipidemias><Early Diagnosis><Encephalon><Enrollment><Epidemic><Epidemiology><Etiology><European><Exhibits><Female><Funding><GFA-Protein><GFAP><GWA study><GWAS><Genetic><Genetic Risk><Genomics><Genotype><Glial Fibrillary Acid Protein><Glial Fibrillary Acidic Protein><Glial Intermediate Filament Protein><Goals><Hypertension><Image><India><Individual><Infrastructure><Knowledge><Language><Lead><Life><Life Cycle><Life Cycle Stages><Life Style><Lifestyle><Linguistic><Linguistics><Link><Longitudinal Studies><MR Imaging><MR Tomography><MRI><MRIs><Machine Learning><Magnetic Resonance Imaging><Measurement><Measures><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Metabolic><Myocardium><NHLBI><NMR Imaging><NMR Tomography><National Heart, Lung, and Blood Institute><Natural History><Neuropsychologies><Neuropsychology><Nuclear Magnetic Resonance Imaging><Organ><Outcome><Participant><Pathway interactions><Pattern><Pb element><Persons><Phase><Phenotype><Plasma><Plasma Serum><Population><Predicting Risk><Predisposition><Preventative intervention><Prevention><Primary Senile Degenerative Dementia><Protocol><Protocols documentation><Research><Reticuloendothelial System, Serum, Plasma><Retina><Risk><Risk Factors><Sampling><Sleep><Social Behavior><South Asian><Span 20><Spectroscopy><Spectrum Analyses><Spectrum Analysis><Standardization><Statistical Methods><Stress><Stroke><Susceptibility><System><Systematics><Therapeutic><Vascular Cognitive Impairment><Vascular Dementia><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Zeugmatography><accelerated aging><accelerated biological age><accelerated biological aging><active followup><adulthood><age acceleration><aged><aged group><aged groups><aged individual><aged individuals><aged people><aged person><aged persons><aged population><aged populations><ages><aging population><artificial intelligence assisted><artificial intelligence augmented><artificial intelligence driven><artificial intelligence integrated><artificial intelligence powered><bio-markers><biobank><biologic><biologic marker><biomarker><biorepository><brain MR imaging><brain MRI><brain attack><brain magnetic resonance imaging><cardiac muscle><cardiometabolic><cardiometabolism><causation><cerebral MR imaging><cerebral MRI><cerebral magnetic resonance imaging><cerebral vascular accident><cerebrovascular accident><cerebrovascular contribution to cognitive impairment><cerebrovascular contributions to cognitive dysfunction><cerebrovascular contributions to dementia><cognitive change><cohort><computer based prediction><dementia risk><diabetes><digital><digital cognitive assessment><digital cognitive test><digital marker><disease causation><early detection><early onset><enhanced with AI><enhanced with Artificial Intelligence><enroll><entire genome><epidemiologic><epidemiological><experience><family structure><follow up><follow-up><followed up><followup><forecasting risk><full genome><gene locus><genetic locus><genome sequencing><genome wide association><genome wide association scan><genome wide association study><genomewide association scan><genomewide association study><genomic location><genomic locus><heart muscle><heavy metal Pb><heavy metal lead><high blood pressure><high dimensional data><high risk><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><imaging><intervention for prevention><late in life><late life><learning network><life course><literate><long-term study><longitudinal design><longitudinal experimental design><longitudinal outcome studies><longitudinal research design><longitudinal study design><machine based learning><machine learning based prediction model><machine learning based predictive model><machine learning prediction><machine learning prediction model><malleable risk><mid life><mid-life><middle age><middle aged><midlife><mild cognitive disorder><mild cognitive impairment><modifiable risk><multi-modal data><multi-modal datasets><multi-modality><multidimensional data><multidimensional datasets><multimodal data><multimodal datasets><multimodality><neural imaging><neuro-imaging><neuroimaging><neuroimaging biomarker><neuroimaging marker><neurological imaging><neuropsychologic><new marker><novel><novel biomarker><novel marker><pathway><phenotypic data><pollutant><population aging><population based><pre-clinical><preclinical><predict risk><predict risks><predicted risk><predicted risks><predicting risks><predictive modeling><predictive risk><predictive tools><predicts risk><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><primary degenerative dementia><retinal imaging><risk factor for dementia><risk for dementia><risk prediction><risk predictions><senile dementia of the Alzheimer type><social culture><social structural><social structure><socio-cultural><socio-demographics><socio-structural><sociobehavior><sociobehavioral><sociocultural><sociodemographics><sociostructural><statistic methods><stroked><strokes><vascular><vascular and cognitive impairment><vascular cognition impairment><vascular cognitive decline><vascular cognitive disease><vascular cognitive disorder><vascular cognitive dysfunction><vascular contributions in dementia><vascular contributions to cognitive decline><vascular contributions to cognitive impairment><vascular contributions to dementia><vascular disease and impaired cognition><vascular dysfunction resulting in cognitive decline><vascular related cognitive decline><vascular related cognitive impairment><vascular related dementia><whole genome><whole genome association analysis><whole genome association study><younger age><♀>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Viswanathan Mohan

EMORY UNIVERSITY, ATLANTA, GA

Good lead · 60/100
Likely hiring
Large award
Active award
$2,442,538
FY 2025

Project Title

P-CARRS-BRAIN: Multi-domain (genetic, socio-behavioral, vascular) risk factors and prediction of Alzheimer’s Disease continuum in South Asians in India

Grant Number:

5R01AG089759-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2024

End Date:

8/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY/ABSTRACT While it is widely acknowledged that Alzheimer’s disease and related dementias (AD/ADRD) have an extended preclinical phase, there are sparse data on the cognitive and pathobiological changes in middle-ages, a critical window for preventative intervention in people likely to...

Research Terms

<21+ years old><AD dementia><AD pathology><AD related dementia><ADRD><AI Augmented><AI assisted><AI driven><AI enhanced><AI integrated><AI powered><Active Follow-up><Address><Adult><Adult Human><Age><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's biomarker><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease biological marker><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease pathology><Alzheimer's disease related dementia><Alzheimer's pathology><Alzheimers Dementia><Alzheimer’s biological marker><Alzheimer’s disease biomarker><Amentia><Apoplexy><Arteriosclerotic Dementia><Artificial Intelligence enhanced><Asian group><Asian individual><Asian people><Asian population><Asians><Assessment instrument><Assessment tool><Astroprotein><Augmented by AI><Augmented by the AI><Augmented with AI><Augmented with the AI><Behavioral><Biological><Biological Markers><Blood Plasma><Blood Vessels><Brain><Brain Nervous System><Brain Vascular Accident><Causality><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Classification><Clinical><Cognition><Cognitive><Collection><Complex><Data><Data Management and Analysis Core><Data Management and Statistical Analysis Core><Data Management and Statistical Core><Dementia><Detection><Diabetes Mellitus><Diagnosis><Digital biomarker><Disease><Disorder><Dyslipidemias><Early Diagnosis><Encephalon><Enrollment><Epidemic><Epidemiology><Etiology><European><Exhibits><Female><Funding><GFA-Protein><GFAP><GWA study><GWAS><Genetic><Genetic Risk><Genomics><Genotype><Glial Fibrillary Acid Protein><Glial Fibrillary Acidic Protein><Glial Intermediate Filament Protein><Goals><Hypertension><Image><India><Individual><Infrastructure><Knowledge><Language><Lead><Life><Life Cycle><Life Cycle Stages><Life Style><Lifestyle><Linguistic><Linguistics><Link><Longitudinal Studies><MR Imaging><MR Tomography><MRI><MRIs><Machine Learning><Magnetic Resonance Imaging><Measurement><Measures><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Metabolic><Myocardium><NHLBI><NMR Imaging><NMR Tomography><National Heart, Lung, and Blood Institute><Natural History><Neuropsychologies><Neuropsychology><Nuclear Magnetic Resonance Imaging><Organ><Outcome><Participant><Pathway interactions><Pattern><Pb element><Persons><Phase><Phenotype><Plasma><Plasma Serum><Population><Predicting Risk><Predisposition><Preventative intervention><Prevention><Primary Senile Degenerative Dementia><Protocol><Protocols documentation><Research><Reticuloendothelial System, Serum, Plasma><Retina><Risk><Risk Factors><Sampling><Sleep><Social Behavior><South Asian><Span 20><Spectroscopy><Spectrum Analyses><Spectrum Analysis><Standardization><Statistical Methods><Stress><Stroke><Susceptibility><System><Systematics><Therapeutic><Vascular Cognitive Impairment><Vascular Dementia><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Zeugmatography><accelerated aging><accelerated biological age><accelerated biological aging><active followup><adulthood><age acceleration><aged><aged group><aged groups><aged individual><aged individuals><aged people><aged person><aged persons><aged population><aged populations><ages><aging population><artificial intelligence assisted><artificial intelligence augmented><artificial intelligence driven><artificial intelligence integrated><artificial intelligence powered><bio-markers><biobank><biologic><biologic marker><biomarker><biorepository><brain MR imaging><brain MRI><brain attack><brain magnetic resonance imaging><cardiac muscle><cardiometabolic><cardiometabolism><causation><cerebral MR imaging><cerebral MRI><cerebral magnetic resonance imaging><cerebral vascular accident><cerebrovascular accident><cerebrovascular contribution to cognitive impairment><cerebrovascular contributions to cognitive dysfunction><cerebrovascular contributions to dementia><cognitive change><cohort><computer based prediction><dementia risk><diabetes><digital><digital cognitive assessment><digital cognitive test><digital marker><disease causation><early detection><early onset><enhanced with AI><enhanced with Artificial Intelligence><enroll><entire genome><epidemiologic><epidemiological><experience><family structure><follow up><follow-up><followed up><followup><forecasting risk><full genome><gene locus><genetic locus><genome sequencing><genome wide association><genome wide association scan><genome wide association study><genomewide association scan><genomewide association study><genomic location><genomic locus><heart muscle><heavy metal Pb><heavy metal lead><high blood pressure><high dimensional data><high risk><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><imaging><intervention for prevention><late in life><late life><learning network><life course><literate><long-term study><longitudinal design><longitudinal experimental design><longitudinal outcome studies><longitudinal research design><longitudinal study design><machine based learning><machine learning based prediction model><machine learning based predictive model><machine learning prediction><machine learning prediction model><malleable risk><mid life><mid-life><middle age><middle aged><midlife><mild cognitive disorder><mild cognitive impairment><modifiable risk><multi-modal data><multi-modal datasets><multi-modality><multidimensional data><multidimensional datasets><multimodal data><multimodal datasets><multimodality><neural imaging><neuro-imaging><neuroimaging><neuroimaging biomarker><neuroimaging marker><neurological imaging><neuropsychologic><new marker><novel><novel biomarker><novel marker><pathway><phenotypic data><pollutant><population aging><population based><pre-clinical><preclinical><predict risk><predict risks><predicted risk><predicted risks><predicting risks><predictive modeling><predictive risk><predictive tools><predicts risk><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><primary degenerative dementia><retinal imaging><risk factor for dementia><risk for dementia><risk prediction><risk predictions><senile dementia of the Alzheimer type><social culture><social structural><social structure><socio-cultural><socio-demographics><socio-structural><sociobehavior><sociobehavioral><sociocultural><sociodemographics><sociostructural><statistic methods><stroked><strokes><vascular><vascular and cognitive impairment><vascular cognition impairment><vascular cognitive decline><vascular cognitive disease><vascular cognitive disorder><vascular cognitive dysfunction><vascular contributions in dementia><vascular contributions to cognitive decline><vascular contributions to cognitive impairment><vascular contributions to dementia><vascular disease and impaired cognition><vascular dysfunction resulting in cognitive decline><vascular related cognitive decline><vascular related cognitive impairment><vascular related dementia><whole genome><whole genome association analysis><whole genome association study><younger age><♀>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Kabayam M Venkat Narayan

EMORY UNIVERSITY, ATLANTA, GA

Good lead · 60/100
Likely hiring
Large award
Active award
$2,442,538
FY 2025

Project Title

P-CARRS-BRAIN: Multi-domain (genetic, socio-behavioral, vascular) risk factors and prediction of Alzheimer’s Disease continuum in South Asians in India

Grant Number:

5R01AG089759-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2024

End Date:

8/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY/ABSTRACT While it is widely acknowledged that Alzheimer’s disease and related dementias (AD/ADRD) have an extended preclinical phase, there are sparse data on the cognitive and pathobiological changes in middle-ages, a critical window for preventative intervention in people likely to...

Research Terms

<21+ years old><AD dementia><AD pathology><AD related dementia><ADRD><AI Augmented><AI assisted><AI driven><AI enhanced><AI integrated><AI powered><Active Follow-up><Address><Adult><Adult Human><Age><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's biomarker><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease biological marker><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease pathology><Alzheimer's disease related dementia><Alzheimer's pathology><Alzheimers Dementia><Alzheimer’s biological marker><Alzheimer’s disease biomarker><Amentia><Apoplexy><Arteriosclerotic Dementia><Artificial Intelligence enhanced><Asian group><Asian individual><Asian people><Asian population><Asians><Assessment instrument><Assessment tool><Astroprotein><Augmented by AI><Augmented by the AI><Augmented with AI><Augmented with the AI><Behavioral><Biological><Biological Markers><Blood Plasma><Blood Vessels><Brain><Brain Nervous System><Brain Vascular Accident><Causality><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Classification><Clinical><Cognition><Cognitive><Collection><Complex><Data><Data Management and Analysis Core><Data Management and Statistical Analysis Core><Data Management and Statistical Core><Dementia><Detection><Diabetes Mellitus><Diagnosis><Digital biomarker><Disease><Disorder><Dyslipidemias><Early Diagnosis><Encephalon><Enrollment><Epidemic><Epidemiology><Etiology><European><Exhibits><Female><Funding><GFA-Protein><GFAP><GWA study><GWAS><Genetic><Genetic Risk><Genomics><Genotype><Glial Fibrillary Acid Protein><Glial Fibrillary Acidic Protein><Glial Intermediate Filament Protein><Goals><Hypertension><Image><India><Individual><Infrastructure><Knowledge><Language><Lead><Life><Life Cycle><Life Cycle Stages><Life Style><Lifestyle><Linguistic><Linguistics><Link><Longitudinal Studies><MR Imaging><MR Tomography><MRI><MRIs><Machine Learning><Magnetic Resonance Imaging><Measurement><Measures><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Metabolic><Myocardium><NHLBI><NMR Imaging><NMR Tomography><National Heart, Lung, and Blood Institute><Natural History><Neuropsychologies><Neuropsychology><Nuclear Magnetic Resonance Imaging><Organ><Outcome><Participant><Pathway interactions><Pattern><Pb element><Persons><Phase><Phenotype><Plasma><Plasma Serum><Population><Predicting Risk><Predisposition><Preventative intervention><Prevention><Primary Senile Degenerative Dementia><Protocol><Protocols documentation><Research><Reticuloendothelial System, Serum, Plasma><Retina><Risk><Risk Factors><Sampling><Sleep><Social Behavior><South Asian><Span 20><Spectroscopy><Spectrum Analyses><Spectrum Analysis><Standardization><Statistical Methods><Stress><Stroke><Susceptibility><System><Systematics><Therapeutic><Vascular Cognitive Impairment><Vascular Dementia><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Zeugmatography><accelerated aging><accelerated biological age><accelerated biological aging><active followup><adulthood><age acceleration><aged><aged group><aged groups><aged individual><aged individuals><aged people><aged person><aged persons><aged population><aged populations><ages><aging population><artificial intelligence assisted><artificial intelligence augmented><artificial intelligence driven><artificial intelligence integrated><artificial intelligence powered><bio-markers><biobank><biologic><biologic marker><biomarker><biorepository><brain MR imaging><brain MRI><brain attack><brain magnetic resonance imaging><cardiac muscle><cardiometabolic><cardiometabolism><causation><cerebral MR imaging><cerebral MRI><cerebral magnetic resonance imaging><cerebral vascular accident><cerebrovascular accident><cerebrovascular contribution to cognitive impairment><cerebrovascular contributions to cognitive dysfunction><cerebrovascular contributions to dementia><cognitive change><cohort><computer based prediction><dementia risk><diabetes><digital><digital cognitive assessment><digital cognitive test><digital marker><disease causation><early detection><early onset><enhanced with AI><enhanced with Artificial Intelligence><enroll><entire genome><epidemiologic><epidemiological><experience><family structure><follow up><follow-up><followed up><followup><forecasting risk><full genome><gene locus><genetic locus><genome sequencing><genome wide association><genome wide association scan><genome wide association study><genomewide association scan><genomewide association study><genomic location><genomic locus><heart muscle><heavy metal Pb><heavy metal lead><high blood pressure><high dimensional data><high risk><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><imaging><intervention for prevention><late in life><late life><learning network><life course><literate><long-term study><longitudinal design><longitudinal experimental design><longitudinal outcome studies><longitudinal research design><longitudinal study design><machine based learning><machine learning based prediction model><machine learning based predictive model><machine learning prediction><machine learning prediction model><malleable risk><mid life><mid-life><middle age><middle aged><midlife><mild cognitive disorder><mild cognitive impairment><modifiable risk><multi-modal data><multi-modal datasets><multi-modality><multidimensional data><multidimensional datasets><multimodal data><multimodal datasets><multimodality><neural imaging><neuro-imaging><neuroimaging><neuroimaging biomarker><neuroimaging marker><neurological imaging><neuropsychologic><new marker><novel><novel biomarker><novel marker><pathway><phenotypic data><pollutant><population aging><population based><pre-clinical><preclinical><predict risk><predict risks><predicted risk><predicted risks><predicting risks><predictive modeling><predictive risk><predictive tools><predicts risk><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><primary degenerative dementia><retinal imaging><risk factor for dementia><risk for dementia><risk prediction><risk predictions><senile dementia of the Alzheimer type><social culture><social structural><social structure><socio-cultural><socio-demographics><socio-structural><sociobehavior><sociobehavioral><sociocultural><sociodemographics><sociostructural><statistic methods><stroked><strokes><vascular><vascular and cognitive impairment><vascular cognition impairment><vascular cognitive decline><vascular cognitive disease><vascular cognitive disorder><vascular cognitive dysfunction><vascular contributions in dementia><vascular contributions to cognitive decline><vascular contributions to cognitive impairment><vascular contributions to dementia><vascular disease and impaired cognition><vascular dysfunction resulting in cognitive decline><vascular related cognitive decline><vascular related cognitive impairment><vascular related dementia><whole genome><whole genome association analysis><whole genome association study><younger age><♀>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Dorairaj Prabhakaran

EMORY UNIVERSITY, ATLANTA, GA

Good lead · 60/100
Likely hiring
Large award
Active award
$2,442,538
FY 2025

Project Title

P-CARRS-BRAIN: Multi-domain (genetic, socio-behavioral, vascular) risk factors and prediction of Alzheimer’s Disease continuum in South Asians in India

Grant Number:

5R01AG089759-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2024

End Date:

8/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY/ABSTRACT While it is widely acknowledged that Alzheimer’s disease and related dementias (AD/ADRD) have an extended preclinical phase, there are sparse data on the cognitive and pathobiological changes in middle-ages, a critical window for preventative intervention in people likely to...

Research Terms

<21+ years old><AD dementia><AD pathology><AD related dementia><ADRD><AI Augmented><AI assisted><AI driven><AI enhanced><AI integrated><AI powered><Active Follow-up><Address><Adult><Adult Human><Age><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's biomarker><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease biological marker><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease pathology><Alzheimer's disease related dementia><Alzheimer's pathology><Alzheimers Dementia><Alzheimer’s biological marker><Alzheimer’s disease biomarker><Amentia><Apoplexy><Arteriosclerotic Dementia><Artificial Intelligence enhanced><Asian group><Asian individual><Asian people><Asian population><Asians><Assessment instrument><Assessment tool><Astroprotein><Augmented by AI><Augmented by the AI><Augmented with AI><Augmented with the AI><Behavioral><Biological><Biological Markers><Blood Plasma><Blood Vessels><Brain><Brain Nervous System><Brain Vascular Accident><Causality><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Classification><Clinical><Cognition><Cognitive><Collection><Complex><Data><Data Management and Analysis Core><Data Management and Statistical Analysis Core><Data Management and Statistical Core><Dementia><Detection><Diabetes Mellitus><Diagnosis><Digital biomarker><Disease><Disorder><Dyslipidemias><Early Diagnosis><Encephalon><Enrollment><Epidemic><Epidemiology><Etiology><European><Exhibits><Female><Funding><GFA-Protein><GFAP><GWA study><GWAS><Genetic><Genetic Risk><Genomics><Genotype><Glial Fibrillary Acid Protein><Glial Fibrillary Acidic Protein><Glial Intermediate Filament Protein><Goals><Hypertension><Image><India><Individual><Infrastructure><Knowledge><Language><Lead><Life><Life Cycle><Life Cycle Stages><Life Style><Lifestyle><Linguistic><Linguistics><Link><Longitudinal Studies><MR Imaging><MR Tomography><MRI><MRIs><Machine Learning><Magnetic Resonance Imaging><Measurement><Measures><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Metabolic><Myocardium><NHLBI><NMR Imaging><NMR Tomography><National Heart, Lung, and Blood Institute><Natural History><Neuropsychologies><Neuropsychology><Nuclear Magnetic Resonance Imaging><Organ><Outcome><Participant><Pathway interactions><Pattern><Pb element><Persons><Phase><Phenotype><Plasma><Plasma Serum><Population><Predicting Risk><Predisposition><Preventative intervention><Prevention><Primary Senile Degenerative Dementia><Protocol><Protocols documentation><Research><Reticuloendothelial System, Serum, Plasma><Retina><Risk><Risk Factors><Sampling><Sleep><Social Behavior><South Asian><Span 20><Spectroscopy><Spectrum Analyses><Spectrum Analysis><Standardization><Statistical Methods><Stress><Stroke><Susceptibility><System><Systematics><Therapeutic><Vascular Cognitive Impairment><Vascular Dementia><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Zeugmatography><accelerated aging><accelerated biological age><accelerated biological aging><active followup><adulthood><age acceleration><aged><aged group><aged groups><aged individual><aged individuals><aged people><aged person><aged persons><aged population><aged populations><ages><aging population><artificial intelligence assisted><artificial intelligence augmented><artificial intelligence driven><artificial intelligence integrated><artificial intelligence powered><bio-markers><biobank><biologic><biologic marker><biomarker><biorepository><brain MR imaging><brain MRI><brain attack><brain magnetic resonance imaging><cardiac muscle><cardiometabolic><cardiometabolism><causation><cerebral MR imaging><cerebral MRI><cerebral magnetic resonance imaging><cerebral vascular accident><cerebrovascular accident><cerebrovascular contribution to cognitive impairment><cerebrovascular contributions to cognitive dysfunction><cerebrovascular contributions to dementia><cognitive change><cohort><computer based prediction><dementia risk><diabetes><digital><digital cognitive assessment><digital cognitive test><digital marker><disease causation><early detection><early onset><enhanced with AI><enhanced with Artificial Intelligence><enroll><entire genome><epidemiologic><epidemiological><experience><family structure><follow up><follow-up><followed up><followup><forecasting risk><full genome><gene locus><genetic locus><genome sequencing><genome wide association><genome wide association scan><genome wide association study><genomewide association scan><genomewide association study><genomic location><genomic locus><heart muscle><heavy metal Pb><heavy metal lead><high blood pressure><high dimensional data><high risk><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><imaging><intervention for prevention><late in life><late life><learning network><life course><literate><long-term study><longitudinal design><longitudinal experimental design><longitudinal outcome studies><longitudinal research design><longitudinal study design><machine based learning><machine learning based prediction model><machine learning based predictive model><machine learning prediction><machine learning prediction model><malleable risk><mid life><mid-life><middle age><middle aged><midlife><mild cognitive disorder><mild cognitive impairment><modifiable risk><multi-modal data><multi-modal datasets><multi-modality><multidimensional data><multidimensional datasets><multimodal data><multimodal datasets><multimodality><neural imaging><neuro-imaging><neuroimaging><neuroimaging biomarker><neuroimaging marker><neurological imaging><neuropsychologic><new marker><novel><novel biomarker><novel marker><pathway><phenotypic data><pollutant><population aging><population based><pre-clinical><preclinical><predict risk><predict risks><predicted risk><predicted risks><predicting risks><predictive modeling><predictive risk><predictive tools><predicts risk><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><primary degenerative dementia><retinal imaging><risk factor for dementia><risk for dementia><risk prediction><risk predictions><senile dementia of the Alzheimer type><social culture><social structural><social structure><socio-cultural><socio-demographics><socio-structural><sociobehavior><sociobehavioral><sociocultural><sociodemographics><sociostructural><statistic methods><stroked><strokes><vascular><vascular and cognitive impairment><vascular cognition impairment><vascular cognitive decline><vascular cognitive disease><vascular cognitive disorder><vascular cognitive dysfunction><vascular contributions in dementia><vascular contributions to cognitive decline><vascular contributions to cognitive impairment><vascular contributions to dementia><vascular disease and impaired cognition><vascular dysfunction resulting in cognitive decline><vascular related cognitive decline><vascular related cognitive impairment><vascular related dementia><whole genome><whole genome association analysis><whole genome association study><younger age><♀>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Suvarna Alladi

EMORY UNIVERSITY, ATLANTA, GA

Good lead · 60/100
Likely hiring
Large award
Active award
$1,124,400
FY 2025

Project Title

P-CARRS-BRAIN: Multi-domain (genetic, socio-behavioral, vascular) risk factors and prediction of Alzheimer’s Disease continuum in South Asians in India

Grant Number:

3R01AG089759-02S2

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2024

End Date:

8/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY/ABSTRACT While it is widely acknowledged that Alzheimer’s disease and related dementias (AD/ADRD) have an extended preclinical phase, there are sparse data on the cognitive and pathobiological changes in middle-ages, a critical window for preventative intervention in people likely to...

Research Terms

<21+ years old><AD dementia><AD pathology><AD related dementia><ADRD><AI Augmented><AI assisted><AI driven><AI enhanced><AI integrated><AI powered><Active Follow-up><Address><Adult><Adult Human><Age><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's biomarker><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease biological marker><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease pathology><Alzheimer's disease related dementia><Alzheimer's pathology><Alzheimers Dementia><Alzheimer’s biological marker><Alzheimer’s disease biomarker><Amentia><Apoplexy><Arteriosclerotic Dementia><Artificial Intelligence enhanced><Asian group><Asian individual><Asian people><Asian population><Asians><Assessment instrument><Assessment tool><Astroprotein><Augmented by AI><Augmented by the AI><Augmented with AI><Augmented with the AI><Behavioral><Biological><Biological Markers><Blood Plasma><Blood Vessels><Brain><Brain Nervous System><Brain Vascular Accident><Causality><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Classification><Clinical><Cognition><Cognitive><Collection><Complex><Data><Data Management and Analysis Core><Data Management and Statistical Analysis Core><Data Management and Statistical Core><Dementia><Detection><Diabetes Mellitus><Diagnosis><Digital biomarker><Disease><Disorder><Dyslipidemias><Early Diagnosis><Encephalon><Enrollment><Epidemic><Epidemiology><Etiology><European><Exhibits><Female><Funding><GFA-Protein><GFAP><GWA study><GWAS><Genetic><Genetic Risk><Genomics><Genotype><Glial Fibrillary Acid Protein><Glial Fibrillary Acidic Protein><Glial Intermediate Filament Protein><Goals><Hypertension><Image><India><Individual><Infrastructure><Knowledge><Language><Lead><Life><Life Cycle><Life Cycle Stages><Life Style><Lifestyle><Linguistic><Linguistics><Link><Longitudinal Studies><MR Imaging><MR Tomography><MRI><MRIs><Machine Learning><Magnetic Resonance Imaging><Measurement><Measures><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Metabolic><Myocardium><NHLBI><NMR Imaging><NMR Tomography><National Heart, Lung, and Blood Institute><Natural History><Neuropsychologies><Neuropsychology><Nuclear Magnetic Resonance Imaging><Organ><Outcome><Participant><Pathway interactions><Pattern><Pb element><Persons><Phase><Phenotype><Plasma><Plasma Serum><Population><Predicting Risk><Predisposition><Preventative intervention><Prevention><Primary Senile Degenerative Dementia><Protocol><Protocols documentation><Research><Reticuloendothelial System, Serum, Plasma><Retina><Risk><Risk Factors><Sampling><Sleep><Social Behavior><South Asian><Span 20><Spectroscopy><Spectrum Analyses><Spectrum Analysis><Standardization><Statistical Methods><Stress><Stroke><Susceptibility><System><Systematics><Therapeutic><Vascular Cognitive Impairment><Vascular Dementia><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Zeugmatography><accelerated aging><accelerated biological age><accelerated biological aging><active followup><adulthood><age acceleration><aged><aged group><aged groups><aged individual><aged individuals><aged people><aged person><aged persons><aged population><aged populations><ages><aging population><artificial intelligence assisted><artificial intelligence augmented><artificial intelligence driven><artificial intelligence integrated><artificial intelligence powered><bio-markers><biobank><biologic><biologic marker><biomarker><biorepository><brain MR imaging><brain MRI><brain attack><brain magnetic resonance imaging><cardiac muscle><cardiometabolic><cardiometabolism><causation><cerebral MR imaging><cerebral MRI><cerebral magnetic resonance imaging><cerebral vascular accident><cerebrovascular accident><cerebrovascular contribution to cognitive impairment><cerebrovascular contributions to cognitive dysfunction><cerebrovascular contributions to dementia><cognitive change><cohort><computer based prediction><dementia risk><diabetes><digital><digital cognitive assessment><digital cognitive test><digital marker><disease causation><early detection><early onset><enhanced with AI><enhanced with Artificial Intelligence><enroll><entire genome><epidemiologic><epidemiological><experience><family structure><follow up><follow-up><followed up><followup><forecasting risk><full genome><gene locus><genetic locus><genome sequencing><genome wide association><genome wide association scan><genome wide association study><genomewide association scan><genomewide association study><genomic location><genomic locus><heart muscle><heavy metal Pb><heavy metal lead><high blood pressure><high dimensional data><high risk><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><imaging><intervention for prevention><late in life><late life><learning network><life course><literate><long-term study><longitudinal design><longitudinal experimental design><longitudinal outcome studies><longitudinal research design><longitudinal study design><machine based learning><machine learning based prediction model><machine learning based predictive model><machine learning prediction><machine learning prediction model><malleable risk><mid life><mid-life><middle age><middle aged><midlife><mild cognitive disorder><mild cognitive impairment><modifiable risk><multi-modal data><multi-modal datasets><multi-modality><multidimensional data><multidimensional datasets><multimodal data><multimodal datasets><multimodality><neural imaging><neuro-imaging><neuroimaging><neuroimaging biomarker><neuroimaging marker><neurological imaging><neuropsychologic><new marker><novel><novel biomarker><novel marker><pathway><phenotypic data><pollutant><population aging><population based><pre-clinical><preclinical><predict risk><predict risks><predicted risk><predicted risks><predicting risks><predictive modeling><predictive risk><predictive tools><predicts risk><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><primary degenerative dementia><retinal imaging><risk factor for dementia><risk for dementia><risk prediction><risk predictions><senile dementia of the Alzheimer type><social culture><social structural><social structure><socio-cultural><socio-demographics><socio-structural><sociobehavior><sociobehavioral><sociocultural><sociodemographics><sociostructural><statistic methods><stroked><strokes><vascular><vascular and cognitive impairment><vascular cognition impairment><vascular cognitive decline><vascular cognitive disease><vascular cognitive disorder><vascular cognitive dysfunction><vascular contributions in dementia><vascular contributions to cognitive decline><vascular contributions to cognitive impairment><vascular contributions to dementia><vascular disease and impaired cognition><vascular dysfunction resulting in cognitive decline><vascular related cognitive decline><vascular related cognitive impairment><vascular related dementia><whole genome><whole genome association analysis><whole genome association study><younger age><♀>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

ALLAN I LEVEY

EMORY UNIVERSITY, ATLANTA, GA

Good lead · 60/100
Likely hiring
Large award
Active award
$1,124,400
FY 2025

Project Title

P-CARRS-BRAIN: Multi-domain (genetic, socio-behavioral, vascular) risk factors and prediction of Alzheimer’s Disease continuum in South Asians in India

Grant Number:

3R01AG089759-02S2

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2024

End Date:

8/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY/ABSTRACT While it is widely acknowledged that Alzheimer’s disease and related dementias (AD/ADRD) have an extended preclinical phase, there are sparse data on the cognitive and pathobiological changes in middle-ages, a critical window for preventative intervention in people likely to...

Research Terms

<21+ years old><AD dementia><AD pathology><AD related dementia><ADRD><AI Augmented><AI assisted><AI driven><AI enhanced><AI integrated><AI powered><Active Follow-up><Address><Adult><Adult Human><Age><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's biomarker><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease biological marker><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease pathology><Alzheimer's disease related dementia><Alzheimer's pathology><Alzheimers Dementia><Alzheimer’s biological marker><Alzheimer’s disease biomarker><Amentia><Apoplexy><Arteriosclerotic Dementia><Artificial Intelligence enhanced><Asian group><Asian individual><Asian people><Asian population><Asians><Assessment instrument><Assessment tool><Astroprotein><Augmented by AI><Augmented by the AI><Augmented with AI><Augmented with the AI><Behavioral><Biological><Biological Markers><Blood Plasma><Blood Vessels><Brain><Brain Nervous System><Brain Vascular Accident><Causality><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Classification><Clinical><Cognition><Cognitive><Collection><Complex><Data><Data Management and Analysis Core><Data Management and Statistical Analysis Core><Data Management and Statistical Core><Dementia><Detection><Diabetes Mellitus><Diagnosis><Digital biomarker><Disease><Disorder><Dyslipidemias><Early Diagnosis><Encephalon><Enrollment><Epidemic><Epidemiology><Etiology><European><Exhibits><Female><Funding><GFA-Protein><GFAP><GWA study><GWAS><Genetic><Genetic Risk><Genomics><Genotype><Glial Fibrillary Acid Protein><Glial Fibrillary Acidic Protein><Glial Intermediate Filament Protein><Goals><Hypertension><Image><India><Individual><Infrastructure><Knowledge><Language><Lead><Life><Life Cycle><Life Cycle Stages><Life Style><Lifestyle><Linguistic><Linguistics><Link><Longitudinal Studies><MR Imaging><MR Tomography><MRI><MRIs><Machine Learning><Magnetic Resonance Imaging><Measurement><Measures><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Metabolic><Myocardium><NHLBI><NMR Imaging><NMR Tomography><National Heart, Lung, and Blood Institute><Natural History><Neuropsychologies><Neuropsychology><Nuclear Magnetic Resonance Imaging><Organ><Outcome><Participant><Pathway interactions><Pattern><Pb element><Persons><Phase><Phenotype><Plasma><Plasma Serum><Population><Predicting Risk><Predisposition><Preventative intervention><Prevention><Primary Senile Degenerative Dementia><Protocol><Protocols documentation><Research><Reticuloendothelial System, Serum, Plasma><Retina><Risk><Risk Factors><Sampling><Sleep><Social Behavior><South Asian><Span 20><Spectroscopy><Spectrum Analyses><Spectrum Analysis><Standardization><Statistical Methods><Stress><Stroke><Susceptibility><System><Systematics><Therapeutic><Vascular Cognitive Impairment><Vascular Dementia><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Zeugmatography><accelerated aging><accelerated biological age><accelerated biological aging><active followup><adulthood><age acceleration><aged><aged group><aged groups><aged individual><aged individuals><aged people><aged person><aged persons><aged population><aged populations><ages><aging population><artificial intelligence assisted><artificial intelligence augmented><artificial intelligence driven><artificial intelligence integrated><artificial intelligence powered><bio-markers><biobank><biologic><biologic marker><biomarker><biorepository><brain MR imaging><brain MRI><brain attack><brain magnetic resonance imaging><cardiac muscle><cardiometabolic><cardiometabolism><causation><cerebral MR imaging><cerebral MRI><cerebral magnetic resonance imaging><cerebral vascular accident><cerebrovascular accident><cerebrovascular contribution to cognitive impairment><cerebrovascular contributions to cognitive dysfunction><cerebrovascular contributions to dementia><cognitive change><cohort><computer based prediction><dementia risk><diabetes><digital><digital cognitive assessment><digital cognitive test><digital marker><disease causation><early detection><early onset><enhanced with AI><enhanced with Artificial Intelligence><enroll><entire genome><epidemiologic><epidemiological><experience><family structure><follow up><follow-up><followed up><followup><forecasting risk><full genome><gene locus><genetic locus><genome sequencing><genome wide association><genome wide association scan><genome wide association study><genomewide association scan><genomewide association study><genomic location><genomic locus><heart muscle><heavy metal Pb><heavy metal lead><high blood pressure><high dimensional data><high risk><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><imaging><intervention for prevention><late in life><late life><learning network><life course><literate><long-term study><longitudinal design><longitudinal experimental design><longitudinal outcome studies><longitudinal research design><longitudinal study design><machine based learning><machine learning based prediction model><machine learning based predictive model><machine learning prediction><machine learning prediction model><malleable risk><mid life><mid-life><middle age><middle aged><midlife><mild cognitive disorder><mild cognitive impairment><modifiable risk><multi-modal data><multi-modal datasets><multi-modality><multidimensional data><multidimensional datasets><multimodal data><multimodal datasets><multimodality><neural imaging><neuro-imaging><neuroimaging><neuroimaging biomarker><neuroimaging marker><neurological imaging><neuropsychologic><new marker><novel><novel biomarker><novel marker><pathway><phenotypic data><pollutant><population aging><population based><pre-clinical><preclinical><predict risk><predict risks><predicted risk><predicted risks><predicting risks><predictive modeling><predictive risk><predictive tools><predicts risk><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><primary degenerative dementia><retinal imaging><risk factor for dementia><risk for dementia><risk prediction><risk predictions><senile dementia of the Alzheimer type><social culture><social structural><social structure><socio-cultural><socio-demographics><socio-structural><sociobehavior><sociobehavioral><sociocultural><sociodemographics><sociostructural><statistic methods><stroked><strokes><vascular><vascular and cognitive impairment><vascular cognition impairment><vascular cognitive decline><vascular cognitive disease><vascular cognitive disorder><vascular cognitive dysfunction><vascular contributions in dementia><vascular contributions to cognitive decline><vascular contributions to cognitive impairment><vascular contributions to dementia><vascular disease and impaired cognition><vascular dysfunction resulting in cognitive decline><vascular related cognitive decline><vascular related cognitive impairment><vascular related dementia><whole genome><whole genome association analysis><whole genome association study><younger age><♀>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Viswanathan Mohan

EMORY UNIVERSITY, ATLANTA, GA

Good lead · 60/100
Likely hiring
Large award
Active award
$1,124,400
FY 2025

Project Title

P-CARRS-BRAIN: Multi-domain (genetic, socio-behavioral, vascular) risk factors and prediction of Alzheimer’s Disease continuum in South Asians in India

Grant Number:

3R01AG089759-02S2

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2024

End Date:

8/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY/ABSTRACT While it is widely acknowledged that Alzheimer’s disease and related dementias (AD/ADRD) have an extended preclinical phase, there are sparse data on the cognitive and pathobiological changes in middle-ages, a critical window for preventative intervention in people likely to...

Research Terms

<21+ years old><AD dementia><AD pathology><AD related dementia><ADRD><AI Augmented><AI assisted><AI driven><AI enhanced><AI integrated><AI powered><Active Follow-up><Address><Adult><Adult Human><Age><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's biomarker><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease biological marker><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease pathology><Alzheimer's disease related dementia><Alzheimer's pathology><Alzheimers Dementia><Alzheimer’s biological marker><Alzheimer’s disease biomarker><Amentia><Apoplexy><Arteriosclerotic Dementia><Artificial Intelligence enhanced><Asian group><Asian individual><Asian people><Asian population><Asians><Assessment instrument><Assessment tool><Astroprotein><Augmented by AI><Augmented by the AI><Augmented with AI><Augmented with the AI><Behavioral><Biological><Biological Markers><Blood Plasma><Blood Vessels><Brain><Brain Nervous System><Brain Vascular Accident><Causality><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Classification><Clinical><Cognition><Cognitive><Collection><Complex><Data><Data Management and Analysis Core><Data Management and Statistical Analysis Core><Data Management and Statistical Core><Dementia><Detection><Diabetes Mellitus><Diagnosis><Digital biomarker><Disease><Disorder><Dyslipidemias><Early Diagnosis><Encephalon><Enrollment><Epidemic><Epidemiology><Etiology><European><Exhibits><Female><Funding><GFA-Protein><GFAP><GWA study><GWAS><Genetic><Genetic Risk><Genomics><Genotype><Glial Fibrillary Acid Protein><Glial Fibrillary Acidic Protein><Glial Intermediate Filament Protein><Goals><Hypertension><Image><India><Individual><Infrastructure><Knowledge><Language><Lead><Life><Life Cycle><Life Cycle Stages><Life Style><Lifestyle><Linguistic><Linguistics><Link><Longitudinal Studies><MR Imaging><MR Tomography><MRI><MRIs><Machine Learning><Magnetic Resonance Imaging><Measurement><Measures><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Metabolic><Myocardium><NHLBI><NMR Imaging><NMR Tomography><National Heart, Lung, and Blood Institute><Natural History><Neuropsychologies><Neuropsychology><Nuclear Magnetic Resonance Imaging><Organ><Outcome><Participant><Pathway interactions><Pattern><Pb element><Persons><Phase><Phenotype><Plasma><Plasma Serum><Population><Predicting Risk><Predisposition><Preventative intervention><Prevention><Primary Senile Degenerative Dementia><Protocol><Protocols documentation><Research><Reticuloendothelial System, Serum, Plasma><Retina><Risk><Risk Factors><Sampling><Sleep><Social Behavior><South Asian><Span 20><Spectroscopy><Spectrum Analyses><Spectrum Analysis><Standardization><Statistical Methods><Stress><Stroke><Susceptibility><System><Systematics><Therapeutic><Vascular Cognitive Impairment><Vascular Dementia><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Zeugmatography><accelerated aging><accelerated biological age><accelerated biological aging><active followup><adulthood><age acceleration><aged><aged group><aged groups><aged individual><aged individuals><aged people><aged person><aged persons><aged population><aged populations><ages><aging population><artificial intelligence assisted><artificial intelligence augmented><artificial intelligence driven><artificial intelligence integrated><artificial intelligence powered><bio-markers><biobank><biologic><biologic marker><biomarker><biorepository><brain MR imaging><brain MRI><brain attack><brain magnetic resonance imaging><cardiac muscle><cardiometabolic><cardiometabolism><causation><cerebral MR imaging><cerebral MRI><cerebral magnetic resonance imaging><cerebral vascular accident><cerebrovascular accident><cerebrovascular contribution to cognitive impairment><cerebrovascular contributions to cognitive dysfunction><cerebrovascular contributions to dementia><cognitive change><cohort><computer based prediction><dementia risk><diabetes><digital><digital cognitive assessment><digital cognitive test><digital marker><disease causation><early detection><early onset><enhanced with AI><enhanced with Artificial Intelligence><enroll><entire genome><epidemiologic><epidemiological><experience><family structure><follow up><follow-up><followed up><followup><forecasting risk><full genome><gene locus><genetic locus><genome sequencing><genome wide association><genome wide association scan><genome wide association study><genomewide association scan><genomewide association study><genomic location><genomic locus><heart muscle><heavy metal Pb><heavy metal lead><high blood pressure><high dimensional data><high risk><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><imaging><intervention for prevention><late in life><late life><learning network><life course><literate><long-term study><longitudinal design><longitudinal experimental design><longitudinal outcome studies><longitudinal research design><longitudinal study design><machine based learning><machine learning based prediction model><machine learning based predictive model><machine learning prediction><machine learning prediction model><malleable risk><mid life><mid-life><middle age><middle aged><midlife><mild cognitive disorder><mild cognitive impairment><modifiable risk><multi-modal data><multi-modal datasets><multi-modality><multidimensional data><multidimensional datasets><multimodal data><multimodal datasets><multimodality><neural imaging><neuro-imaging><neuroimaging><neuroimaging biomarker><neuroimaging marker><neurological imaging><neuropsychologic><new marker><novel><novel biomarker><novel marker><pathway><phenotypic data><pollutant><population aging><population based><pre-clinical><preclinical><predict risk><predict risks><predicted risk><predicted risks><predicting risks><predictive modeling><predictive risk><predictive tools><predicts risk><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><primary degenerative dementia><retinal imaging><risk factor for dementia><risk for dementia><risk prediction><risk predictions><senile dementia of the Alzheimer type><social culture><social structural><social structure><socio-cultural><socio-demographics><socio-structural><sociobehavior><sociobehavioral><sociocultural><sociodemographics><sociostructural><statistic methods><stroked><strokes><vascular><vascular and cognitive impairment><vascular cognition impairment><vascular cognitive decline><vascular cognitive disease><vascular cognitive disorder><vascular cognitive dysfunction><vascular contributions in dementia><vascular contributions to cognitive decline><vascular contributions to cognitive impairment><vascular contributions to dementia><vascular disease and impaired cognition><vascular dysfunction resulting in cognitive decline><vascular related cognitive decline><vascular related cognitive impairment><vascular related dementia><whole genome><whole genome association analysis><whole genome association study><younger age><♀>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Kabayam M Venkat Narayan

EMORY UNIVERSITY, ATLANTA, GA

Good lead · 60/100
Likely hiring
Large award
Active award
$1,124,400
FY 2025

Project Title

P-CARRS-BRAIN: Multi-domain (genetic, socio-behavioral, vascular) risk factors and prediction of Alzheimer’s Disease continuum in South Asians in India

Grant Number:

3R01AG089759-02S2

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2024

End Date:

8/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY/ABSTRACT While it is widely acknowledged that Alzheimer’s disease and related dementias (AD/ADRD) have an extended preclinical phase, there are sparse data on the cognitive and pathobiological changes in middle-ages, a critical window for preventative intervention in people likely to...

Research Terms

<21+ years old><AD dementia><AD pathology><AD related dementia><ADRD><AI Augmented><AI assisted><AI driven><AI enhanced><AI integrated><AI powered><Active Follow-up><Address><Adult><Adult Human><Age><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's biomarker><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease biological marker><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease pathology><Alzheimer's disease related dementia><Alzheimer's pathology><Alzheimers Dementia><Alzheimer’s biological marker><Alzheimer’s disease biomarker><Amentia><Apoplexy><Arteriosclerotic Dementia><Artificial Intelligence enhanced><Asian group><Asian individual><Asian people><Asian population><Asians><Assessment instrument><Assessment tool><Astroprotein><Augmented by AI><Augmented by the AI><Augmented with AI><Augmented with the AI><Behavioral><Biological><Biological Markers><Blood Plasma><Blood Vessels><Brain><Brain Nervous System><Brain Vascular Accident><Causality><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Classification><Clinical><Cognition><Cognitive><Collection><Complex><Data><Data Management and Analysis Core><Data Management and Statistical Analysis Core><Data Management and Statistical Core><Dementia><Detection><Diabetes Mellitus><Diagnosis><Digital biomarker><Disease><Disorder><Dyslipidemias><Early Diagnosis><Encephalon><Enrollment><Epidemic><Epidemiology><Etiology><European><Exhibits><Female><Funding><GFA-Protein><GFAP><GWA study><GWAS><Genetic><Genetic Risk><Genomics><Genotype><Glial Fibrillary Acid Protein><Glial Fibrillary Acidic Protein><Glial Intermediate Filament Protein><Goals><Hypertension><Image><India><Individual><Infrastructure><Knowledge><Language><Lead><Life><Life Cycle><Life Cycle Stages><Life Style><Lifestyle><Linguistic><Linguistics><Link><Longitudinal Studies><MR Imaging><MR Tomography><MRI><MRIs><Machine Learning><Magnetic Resonance Imaging><Measurement><Measures><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Metabolic><Myocardium><NHLBI><NMR Imaging><NMR Tomography><National Heart, Lung, and Blood Institute><Natural History><Neuropsychologies><Neuropsychology><Nuclear Magnetic Resonance Imaging><Organ><Outcome><Participant><Pathway interactions><Pattern><Pb element><Persons><Phase><Phenotype><Plasma><Plasma Serum><Population><Predicting Risk><Predisposition><Preventative intervention><Prevention><Primary Senile Degenerative Dementia><Protocol><Protocols documentation><Research><Reticuloendothelial System, Serum, Plasma><Retina><Risk><Risk Factors><Sampling><Sleep><Social Behavior><South Asian><Span 20><Spectroscopy><Spectrum Analyses><Spectrum Analysis><Standardization><Statistical Methods><Stress><Stroke><Susceptibility><System><Systematics><Therapeutic><Vascular Cognitive Impairment><Vascular Dementia><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Zeugmatography><accelerated aging><accelerated biological age><accelerated biological aging><active followup><adulthood><age acceleration><aged><aged group><aged groups><aged individual><aged individuals><aged people><aged person><aged persons><aged population><aged populations><ages><aging population><artificial intelligence assisted><artificial intelligence augmented><artificial intelligence driven><artificial intelligence integrated><artificial intelligence powered><bio-markers><biobank><biologic><biologic marker><biomarker><biorepository><brain MR imaging><brain MRI><brain attack><brain magnetic resonance imaging><cardiac muscle><cardiometabolic><cardiometabolism><causation><cerebral MR imaging><cerebral MRI><cerebral magnetic resonance imaging><cerebral vascular accident><cerebrovascular accident><cerebrovascular contribution to cognitive impairment><cerebrovascular contributions to cognitive dysfunction><cerebrovascular contributions to dementia><cognitive change><cohort><computer based prediction><dementia risk><diabetes><digital><digital cognitive assessment><digital cognitive test><digital marker><disease causation><early detection><early onset><enhanced with AI><enhanced with Artificial Intelligence><enroll><entire genome><epidemiologic><epidemiological><experience><family structure><follow up><follow-up><followed up><followup><forecasting risk><full genome><gene locus><genetic locus><genome sequencing><genome wide association><genome wide association scan><genome wide association study><genomewide association scan><genomewide association study><genomic location><genomic locus><heart muscle><heavy metal Pb><heavy metal lead><high blood pressure><high dimensional data><high risk><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><imaging><intervention for prevention><late in life><late life><learning network><life course><literate><long-term study><longitudinal design><longitudinal experimental design><longitudinal outcome studies><longitudinal research design><longitudinal study design><machine based learning><machine learning based prediction model><machine learning based predictive model><machine learning prediction><machine learning prediction model><malleable risk><mid life><mid-life><middle age><middle aged><midlife><mild cognitive disorder><mild cognitive impairment><modifiable risk><multi-modal data><multi-modal datasets><multi-modality><multidimensional data><multidimensional datasets><multimodal data><multimodal datasets><multimodality><neural imaging><neuro-imaging><neuroimaging><neuroimaging biomarker><neuroimaging marker><neurological imaging><neuropsychologic><new marker><novel><novel biomarker><novel marker><pathway><phenotypic data><pollutant><population aging><population based><pre-clinical><preclinical><predict risk><predict risks><predicted risk><predicted risks><predicting risks><predictive modeling><predictive risk><predictive tools><predicts risk><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><primary degenerative dementia><retinal imaging><risk factor for dementia><risk for dementia><risk prediction><risk predictions><senile dementia of the Alzheimer type><social culture><social structural><social structure><socio-cultural><socio-demographics><socio-structural><sociobehavior><sociobehavioral><sociocultural><sociodemographics><sociostructural><statistic methods><stroked><strokes><vascular><vascular and cognitive impairment><vascular cognition impairment><vascular cognitive decline><vascular cognitive disease><vascular cognitive disorder><vascular cognitive dysfunction><vascular contributions in dementia><vascular contributions to cognitive decline><vascular contributions to cognitive impairment><vascular contributions to dementia><vascular disease and impaired cognition><vascular dysfunction resulting in cognitive decline><vascular related cognitive decline><vascular related cognitive impairment><vascular related dementia><whole genome><whole genome association analysis><whole genome association study><younger age><♀>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Dorairaj Prabhakaran

EMORY UNIVERSITY, ATLANTA, GA

Good lead · 60/100
Likely hiring
Large award
Active award
$1,124,400
FY 2025

Project Title

P-CARRS-BRAIN: Multi-domain (genetic, socio-behavioral, vascular) risk factors and prediction of Alzheimer’s Disease continuum in South Asians in India

Grant Number:

3R01AG089759-02S2

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2024

End Date:

8/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY/ABSTRACT While it is widely acknowledged that Alzheimer’s disease and related dementias (AD/ADRD) have an extended preclinical phase, there are sparse data on the cognitive and pathobiological changes in middle-ages, a critical window for preventative intervention in people likely to...

Research Terms

<21+ years old><AD dementia><AD pathology><AD related dementia><ADRD><AI Augmented><AI assisted><AI driven><AI enhanced><AI integrated><AI powered><Active Follow-up><Address><Adult><Adult Human><Age><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's biomarker><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease biological marker><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease pathology><Alzheimer's disease related dementia><Alzheimer's pathology><Alzheimers Dementia><Alzheimer’s biological marker><Alzheimer’s disease biomarker><Amentia><Apoplexy><Arteriosclerotic Dementia><Artificial Intelligence enhanced><Asian group><Asian individual><Asian people><Asian population><Asians><Assessment instrument><Assessment tool><Astroprotein><Augmented by AI><Augmented by the AI><Augmented with AI><Augmented with the AI><Behavioral><Biological><Biological Markers><Blood Plasma><Blood Vessels><Brain><Brain Nervous System><Brain Vascular Accident><Causality><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Classification><Clinical><Cognition><Cognitive><Collection><Complex><Data><Data Management and Analysis Core><Data Management and Statistical Analysis Core><Data Management and Statistical Core><Dementia><Detection><Diabetes Mellitus><Diagnosis><Digital biomarker><Disease><Disorder><Dyslipidemias><Early Diagnosis><Encephalon><Enrollment><Epidemic><Epidemiology><Etiology><European><Exhibits><Female><Funding><GFA-Protein><GFAP><GWA study><GWAS><Genetic><Genetic Risk><Genomics><Genotype><Glial Fibrillary Acid Protein><Glial Fibrillary Acidic Protein><Glial Intermediate Filament Protein><Goals><Hypertension><Image><India><Individual><Infrastructure><Knowledge><Language><Lead><Life><Life Cycle><Life Cycle Stages><Life Style><Lifestyle><Linguistic><Linguistics><Link><Longitudinal Studies><MR Imaging><MR Tomography><MRI><MRIs><Machine Learning><Magnetic Resonance Imaging><Measurement><Measures><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Metabolic><Myocardium><NHLBI><NMR Imaging><NMR Tomography><National Heart, Lung, and Blood Institute><Natural History><Neuropsychologies><Neuropsychology><Nuclear Magnetic Resonance Imaging><Organ><Outcome><Participant><Pathway interactions><Pattern><Pb element><Persons><Phase><Phenotype><Plasma><Plasma Serum><Population><Predicting Risk><Predisposition><Preventative intervention><Prevention><Primary Senile Degenerative Dementia><Protocol><Protocols documentation><Research><Reticuloendothelial System, Serum, Plasma><Retina><Risk><Risk Factors><Sampling><Sleep><Social Behavior><South Asian><Span 20><Spectroscopy><Spectrum Analyses><Spectrum Analysis><Standardization><Statistical Methods><Stress><Stroke><Susceptibility><System><Systematics><Therapeutic><Vascular Cognitive Impairment><Vascular Dementia><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Zeugmatography><accelerated aging><accelerated biological age><accelerated biological aging><active followup><adulthood><age acceleration><aged><aged group><aged groups><aged individual><aged individuals><aged people><aged person><aged persons><aged population><aged populations><ages><aging population><artificial intelligence assisted><artificial intelligence augmented><artificial intelligence driven><artificial intelligence integrated><artificial intelligence powered><bio-markers><biobank><biologic><biologic marker><biomarker><biorepository><brain MR imaging><brain MRI><brain attack><brain magnetic resonance imaging><cardiac muscle><cardiometabolic><cardiometabolism><causation><cerebral MR imaging><cerebral MRI><cerebral magnetic resonance imaging><cerebral vascular accident><cerebrovascular accident><cerebrovascular contribution to cognitive impairment><cerebrovascular contributions to cognitive dysfunction><cerebrovascular contributions to dementia><cognitive change><cohort><computer based prediction><dementia risk><diabetes><digital><digital cognitive assessment><digital cognitive test><digital marker><disease causation><early detection><early onset><enhanced with AI><enhanced with Artificial Intelligence><enroll><entire genome><epidemiologic><epidemiological><experience><family structure><follow up><follow-up><followed up><followup><forecasting risk><full genome><gene locus><genetic locus><genome sequencing><genome wide association><genome wide association scan><genome wide association study><genomewide association scan><genomewide association study><genomic location><genomic locus><heart muscle><heavy metal Pb><heavy metal lead><high blood pressure><high dimensional data><high risk><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><imaging><intervention for prevention><late in life><late life><learning network><life course><literate><long-term study><longitudinal design><longitudinal experimental design><longitudinal outcome studies><longitudinal research design><longitudinal study design><machine based learning><machine learning based prediction model><machine learning based predictive model><machine learning prediction><machine learning prediction model><malleable risk><mid life><mid-life><middle age><middle aged><midlife><mild cognitive disorder><mild cognitive impairment><modifiable risk><multi-modal data><multi-modal datasets><multi-modality><multidimensional data><multidimensional datasets><multimodal data><multimodal datasets><multimodality><neural imaging><neuro-imaging><neuroimaging><neuroimaging biomarker><neuroimaging marker><neurological imaging><neuropsychologic><new marker><novel><novel biomarker><novel marker><pathway><phenotypic data><pollutant><population aging><population based><pre-clinical><preclinical><predict risk><predict risks><predicted risk><predicted risks><predicting risks><predictive modeling><predictive risk><predictive tools><predicts risk><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><primary degenerative dementia><retinal imaging><risk factor for dementia><risk for dementia><risk prediction><risk predictions><senile dementia of the Alzheimer type><social culture><social structural><social structure><socio-cultural><socio-demographics><socio-structural><sociobehavior><sociobehavioral><sociocultural><sociodemographics><sociostructural><statistic methods><stroked><strokes><vascular><vascular and cognitive impairment><vascular cognition impairment><vascular cognitive decline><vascular cognitive disease><vascular cognitive disorder><vascular cognitive dysfunction><vascular contributions in dementia><vascular contributions to cognitive decline><vascular contributions to cognitive impairment><vascular contributions to dementia><vascular disease and impaired cognition><vascular dysfunction resulting in cognitive decline><vascular related cognitive decline><vascular related cognitive impairment><vascular related dementia><whole genome><whole genome association analysis><whole genome association study><younger age><♀>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

HAMID RABB

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

Good lead · 60/100
Likely hiring
Large award
Active award
$1,031,754
FY 2025

Project Title

Clinically Relevant Pharmacologic and Immunomodulatory Strategies to Achieve Long-term Survival of Kidney Xenografts in Primates

Grant Number:

1R01AI198975-01

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/2/2025

End Date:

8/31/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Xenotransplantation (XTx) represents a possible solution to the organ shortage crisis and is an imminent clinical reality with long-term xenograft survival in pig-to-nonhuman primate (NHP) heart and kidney large animal models, and short-term success in recent human decedent and clinical studies. We ...

Research Terms

<Address><Allogenic><Allograft Tolerance><Animal Model><Animal Models and Related Studies><Animals><Anti-Inflammatories><Anti-Inflammatory Agents><Anti-inflammatory><Antigens><Assay><B-Cell Activation><Baboons><Binding><Bioassay><Biological Assay><Biopsy><Blood Plasma Cell><Bp50><CD152><CD152 Antigen><CD152 Gene><CD154><CD40><CD40L><CD40LG><CDW40><CTLA 4><CTLA-4 Gene><CTLA4><CTLA4 gene><CTLA4-TM><Chronic><Clinical><Clinical Research><Clinical Study><Clinical Trials><Complement><Complement Proteins><Creatinine><Cytotoxic T-Lymphocyte Protein 4><Cytotoxic T-Lymphocyte-Associated Antigen 4><Cytotoxic T-Lymphocyte-Associated Protein 4><Cytotoxic T-Lymphocyte-Associated Serine Esterase-4><Data><Deposit><Deposition><Drugs><Endothelium><Ensure><Event><FDA approved><Failure><Family suidae><Genetic><Goals><Graft Survival><Heart><Heterograft><Heterologous Transplantation><Histologic><Histologically><Hour><Human><Hypothermia><Immune Modulation Therapy><Immunomodulation><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><In Vitro><Infection><Injury><Ischemia-Reperfusion Injury><Kidney><Kidney Urinary System><Life><MGC9013><Maintenance><Mediating><Medication><Methods><Modern Man><Modification><Molecular Interaction><Organ><Organ Procurements><Papio><Pathway interactions><Patients><Perfusion><Pharmaceutical Preparations><Pigs><Plasma Cells><Plasmacytes><Play><Preclinical data><Primates><Primates Mammals><Regimen><Regulation><Reperfusion Damage><Reperfusion Injury><Reporting><Risk><Severities><Site><Source><Suidae><Swine><TNFRSF5><TNFRSF5 gene><TNFSF5><TNFSF5 gene><TRAP Gene><Tacrolimus><Testing><Thymus><Thymus Gland><Thymus Proper><Thymus Reticuloendothelial System><Transplantation><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><Vascularization><Xenograft><Xenograft procedure><Xenotransplantation><activated B cells><animal facility><antibody rejection><antibody-mediated rejection><clinical relevance><clinical translation><clinically relevant><clinically translatable><complementation><cytotoxic T-lymphocyte antigen 4><drug/agent><graft dysfunction><graft function><immune modulating strategy><immune modulation><immune modulatory strategy><immune modulatory therapies><immune modulatory treatment><immune regulation><immune regulation therapy><immune regulation treatment><immune regulatory therapy><immune suppression><immune suppressive activity><immune suppressive function><immune-modulation treatment><immunogen><immunogenicity><immunologic reactivity control><immunomodulation therapy><immunomodulation treatment><immunomodulator therapies><immunomodulator treatment><immunomodulator-based therapies><immunomodulatory><immunomodulatory biologics><immunomodulatory strategy><immunomodulatory therapies><immunomodulatory treatment><immunoregulation><immunoregulatory><immunoregulatory therapy><immunoregulatory treatment><immunosuppressive activity><immunosuppressive function><immunosuppressive response><in vivo><injuries><kidney heterograft><kidney xenograft><model of animal><natural hypothermia><non-human primate><nonhuman primate><novel><p50><pathogen><pathway><pharmacologic><plasmocyte><porcine><pre-clinical study><preclinical findings><preclinical information><preclinical study><preservation><prevent><preventing><renal><renal heterograft><renal xenograft><safety and feasibility><success><suid><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment><therapeutic immunomodulation><therapeutic immunoregulation><transplant><transplant model><virtual><xeno-transplant><xeno-transplantation>
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KAZUHIKO YAMADA

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

Good lead · 60/100
Likely hiring
Large award
Active award
$1,031,754
FY 2025

Project Title

Clinically Relevant Pharmacologic and Immunomodulatory Strategies to Achieve Long-term Survival of Kidney Xenografts in Primates

Grant Number:

1R01AI198975-01

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/2/2025

End Date:

8/31/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Xenotransplantation (XTx) represents a possible solution to the organ shortage crisis and is an imminent clinical reality with long-term xenograft survival in pig-to-nonhuman primate (NHP) heart and kidney large animal models, and short-term success in recent human decedent and clinical studies. We ...

Research Terms

<Address><Allogenic><Allograft Tolerance><Animal Model><Animal Models and Related Studies><Animals><Anti-Inflammatories><Anti-Inflammatory Agents><Anti-inflammatory><Antigens><Assay><B-Cell Activation><Baboons><Binding><Bioassay><Biological Assay><Biopsy><Blood Plasma Cell><Bp50><CD152><CD152 Antigen><CD152 Gene><CD154><CD40><CD40L><CD40LG><CDW40><CTLA 4><CTLA-4 Gene><CTLA4><CTLA4 gene><CTLA4-TM><Chronic><Clinical><Clinical Research><Clinical Study><Clinical Trials><Complement><Complement Proteins><Creatinine><Cytotoxic T-Lymphocyte Protein 4><Cytotoxic T-Lymphocyte-Associated Antigen 4><Cytotoxic T-Lymphocyte-Associated Protein 4><Cytotoxic T-Lymphocyte-Associated Serine Esterase-4><Data><Deposit><Deposition><Drugs><Endothelium><Ensure><Event><FDA approved><Failure><Family suidae><Genetic><Goals><Graft Survival><Heart><Heterograft><Heterologous Transplantation><Histologic><Histologically><Hour><Human><Hypothermia><Immune Modulation Therapy><Immunomodulation><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><In Vitro><Infection><Injury><Ischemia-Reperfusion Injury><Kidney><Kidney Urinary System><Life><MGC9013><Maintenance><Mediating><Medication><Methods><Modern Man><Modification><Molecular Interaction><Organ><Organ Procurements><Papio><Pathway interactions><Patients><Perfusion><Pharmaceutical Preparations><Pigs><Plasma Cells><Plasmacytes><Play><Preclinical data><Primates><Primates Mammals><Regimen><Regulation><Reperfusion Damage><Reperfusion Injury><Reporting><Risk><Severities><Site><Source><Suidae><Swine><TNFRSF5><TNFRSF5 gene><TNFSF5><TNFSF5 gene><TRAP Gene><Tacrolimus><Testing><Thymus><Thymus Gland><Thymus Proper><Thymus Reticuloendothelial System><Transplantation><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><Vascularization><Xenograft><Xenograft procedure><Xenotransplantation><activated B cells><animal facility><antibody rejection><antibody-mediated rejection><clinical relevance><clinical translation><clinically relevant><clinically translatable><complementation><cytotoxic T-lymphocyte antigen 4><drug/agent><graft dysfunction><graft function><immune modulating strategy><immune modulation><immune modulatory strategy><immune modulatory therapies><immune modulatory treatment><immune regulation><immune regulation therapy><immune regulation treatment><immune regulatory therapy><immune suppression><immune suppressive activity><immune suppressive function><immune-modulation treatment><immunogen><immunogenicity><immunologic reactivity control><immunomodulation therapy><immunomodulation treatment><immunomodulator therapies><immunomodulator treatment><immunomodulator-based therapies><immunomodulatory><immunomodulatory biologics><immunomodulatory strategy><immunomodulatory therapies><immunomodulatory treatment><immunoregulation><immunoregulatory><immunoregulatory therapy><immunoregulatory treatment><immunosuppressive activity><immunosuppressive function><immunosuppressive response><in vivo><injuries><kidney heterograft><kidney xenograft><model of animal><natural hypothermia><non-human primate><nonhuman primate><novel><p50><pathogen><pathway><pharmacologic><plasmocyte><porcine><pre-clinical study><preclinical findings><preclinical information><preclinical study><preservation><prevent><preventing><renal><renal heterograft><renal xenograft><safety and feasibility><success><suid><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment><therapeutic immunomodulation><therapeutic immunoregulation><transplant><transplant model><virtual><xeno-transplant><xeno-transplantation>
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Carla Rose Nowosad

NEW YORK UNIVERSITY SCHOOL OF MEDICINE, NEW YORK, NY

Good lead · 60/100
Likely hiring
Above-average budget
Active award
$791,797
FY 2026

Project Title

Intestinal Programming of Gut-Associated Germinal Centers

Grant Number:

1R01AI190164-01A1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/4/2026

End Date:

1/31/2031

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY In the healthy intestine, the microbiota and intestinal immune system are intimately linked. One of the major regulators of the microbiome is the mucosal antibody, IgA, produced by intestinal B cells, which exerts unique immunomodulatory functions on bacterial communities. Failures i...

Research Terms

<7S Gamma Globulin><Address><Adherence><Affinity><Alleles><Allelomorphs><Anatomic Sites><Anatomic structures><Anatomy><Animals><Antibodies><Antibody Response><Antigens><Area><Assay><Autoimmune Status><Autoimmunity><Automobile Driving><Autoregulation><B blood cells><B cell><B cell receptor><B cells><B-Cell Activation><B-Cell Antigen Receptor><B-Cell Receptor Binding><B-Cells><B-Lymphocytes><B-cell><Bacteria><Behavior><Binding><Bioassay><Biological Assay><Body Tissues><Bone Marrow><Bone Marrow Reticuloendothelial System><Bp50><CD40><CDW40><Cancers><Cell Body><Cell Communication and Signaling><Cell Signaling><Cell model><Cells><Cellular model><Chimera><Chimera organism><Chronic><Class Switching><Class Switchings><Clonality><Clone Cells><Color><Communities><Coupled><Data><Disease><Disease Outcome><Disorder><Ecologic Systems><Ecological Systems><Ecosystem><Education><Educational aspects><Effectiveness><Environment><Evolution><Exposure to><Failure><Generations><Genetic><Germinal Center><Health><Homeostasis><Host Factor><Host Factor Protein><IgA><IgA FcR><IgA receptor><IgG><Image><Immune><Immune Regulators><Immune system><Immunes><Immunization><Immunoglobulin A><Immunoglobulin Class Switching><Immunoglobulin Class Switchings><Immunoglobulin G><Immunomodulation><Immunomodulators><Impairment><Infection><Infectious Diseases / Laboratory><Infectious Diseases Research><Inflammation><Inflammatory Bowel Diseases><Inflammatory Bowel Disorder><Integration Host Factors><Intermediary Metabolism><Intestinal><Intestinal Diseases><Intestinal Disorder><Intestines><Intracellular Communication and Signaling><Isotype Switching><Isotype Switchings><Knowledge><Ligands><Link><Location><MGC9013><Malignant Neoplasms><Malignant Tumor><Maps><Measures><Membrane><Memory><Mental Depression><Metabolic Diseases><Metabolic Disorder><Metabolic Processes><Metabolism><Methods><Mice><Mice Mammals><Microanatomy><Microscopic Anatomy><Modeling><Molecular><Molecular Interaction><Mouse Strains><Mucosa><Mucosal Tissue><Mucous Membrane><Murine><Mus><Obesity><Physiologic><Physiological><Physiological Homeostasis><Production><Reaction><Receptor Activation><Receptor Signaling><Regulation><Research><Role><Shapes><Signal Transduction><Signal Transduction Systems><Signaling><Site><Specificity><Structure of germinal center of lymph node><TLR protein><TNFRSF5><TNFRSF5 gene><Tail><Testing><Therapeutic><Therapeutic Intervention><Thesaurismosis><Tissues><Toll-Like Receptor Family Gene><Toll-like receptors><Training><Transgenic Mice><Transgenic Organisms><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><activated B cells><adiposity><antigen binding><antigen bound><bacterial community><biological signal transduction><bowel><chimeras><commensal flora><commensal microbes><commensal microbiota><commensal microflora><corpulence><depression><desensitization><design><designing><driving><dysbacteriosis><dysbiosis><dysbiotic><fitness><flexibility><flexible><gut homeostasis><high definition><high-resolution><imaging><imaging approach><imaging based approach><imaging platform><immune microenvironment><immune modulation><immune modulators><immune regulation><immunogen><immunoglobulin A Fc receptor><immunoglobulin A receptor><immunologic reactivity control><immunological synapse formation><immunomodulatory><immunomodulatory molecules><immunoregulation><immunoregulator><immunoregulatory><immunoregulatory molecules><immunosuppressive microenvironment><immunosuppressive tumor microenvironment><imprint><in vivo><inflammatory disease of the intestine><inflammatory disorder of the intestine><insight><interest><intervention therapy><intestinal autoinflammation><intestine disease><intestine disorder><malignancy><membrane structure><metabolism disorder><microbial><microbial composition><microbial consortia><microbial flora><microbial imbalance><microbiome><microbiome community composition><microbiome composition><microbiome species composition><microbiome structure><microbiota><microbiota composition><microflora><mouse model><multispecies consortia><murine model><neoplasm/cancer><novel><p50><pathogen><permissiveness><programs><receptor function><response><social role><tool><transgenic><tumor immune microenvironment><tumor-immune system interactions>
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Vipul Shukla

NORTHWESTERN UNIVERSITY, CHICAGO, IL

Good lead · 60/100
Likely hiring
Above-average budget
Active award
$638,259
FY 2026

Project Title

Regulation of germinal center homeostasis by the BAF complex

Grant Number:

5R01AI187142-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

11/12/2024

End Date:

10/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

Summary/Abstract Germinal Centers (GCs) are specialized anatomical sites in the secondary lymphoid tissues where high-quality adaptive immune responses are mounted. B cells within GCs undergo intricate transcriptional and epigenetic transitions to ultimately generate effective humoral immune respons...

Research Terms

<AP-1><AP-1 Enhancer-Binding Protein><AP1><AP1 protein><ARID Domain><ARID1A><ARID1A gene><AT- rich interactive domain-containing protein 1A><AT-Rich Interaction Domain><AT-Rich Interactive Domain><AT-rich interactive domain 1A gene><Activator Protein-1><Address><Anatomic Sites><Anatomic structures><Anatomy><Anti-Inflammatories><Anti-Inflammatory Agents><Anti-inflammatory><Antibodies><Antibody Affinity><Antibody Response><Automobile Driving><Autoregulation><B blood cells><B cell><B cell differentiation><B cells><B lymphocyte differentiation><B lymphoma><B-Cell Activation><B-Cell Deficiency><B-Cell Lymphomas><B-Cells><B-Lymphocytes><B-cell><BRG-1><BRG-1 Gene><BRG1><BRG1 Gene><BRIGHT Domain><BRM/SWI2-Related Gene-1><Basal Transcription Factor><Basal transcription factor genes><Biology><Blood Neutrophil><Blood Polymorphonuclear Neutrophil><Blood Serum><Blood monocyte><Body Tissues><Bone Marrow Examination><Cell Body><Cell Communication and Signaling><Cell Differentiation><Cell Differentiation process><Cell Signaling><Cells><Cellular biology><Chromatin><Collaborations><Complex><DLBCL><Defense Mechanisms><Development><Dexamethasone><Diffuse Large B-Cell Lymphoma><Disease><Disorder><Enhancer-Binding Protein AP1><Ensure><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Eukaryota><Eukaryote><Exhibits><Extramedullary><Gene Expression><Gene Transcription><General Transcription Factor Gene><General Transcription Factors><Generations><Genes><Genetic Transcription><Genomic Segment><Genomics><Germinal Center><Glucocorticoids><Hematologic Cancer><Hematologic Malignancies><Hematologic Neoplasms><Hematological Malignancies><Hematological Neoplasms><Hematological Tumor><Hematopoietic Cancer><Homeostasis><Human><Immune><Immune response><Immune system><Immunes><Immunity><Immunochemical Immunologic><Immunologic><Immunological><Immunologically><Immunologics><Infection><Infiltration><Inflammation><Inflammatory><Intracellular Communication and Signaling><Link><Lymphatic Tissue><Lymphoid Tissue><Malignant Hematologic Neoplasm><Maps><Marrow Neutrophil><Marrow monocyte><Mediating><Modern Man><Mutate><Myeloid Cells><Myelopoiesis><Neutrophilic Granulocyte><Neutrophilic Leukocyte><Nucleosomes><Outcome><P50 Mechanism><P50 Program><Patients><Physiological Homeostasis><Play><Polymorphonuclear Cell><Polymorphonuclear Leukocytes><Polymorphonuclear Neutrophils><RNA Expression><Regulation><Role><SMARCA4><SMARCA4 gene><SNF2-Beta><SWI/SNF-Related, Matrix-Associated, Actin-Dependent Regulator of Chromatin, Subfamily A, Member 4 Gene><Sepsis><Serum><Signal Transduction><Signal Transduction Systems><Signaling><Slide><Solid><Source><Specialized Center><Structure of germinal center of lymph node><Testing><Tissues><Transcription><Transcription Factor AP-1><Transcription Factor Proto-Oncogene><Transcription factor genes><Work><activated B cells><adaptive immune response><antigen antibody affinity><biological signal transduction><bone marrow exam><cell biology><cellular development><cellular differentiation><chromatin remodeling><cytokine><developmental><driving><epigenetic regulation><epigenetically><gene locus><gene signatures><genetic locus><genetic signature><genome profiling><genome segment><genomic location><genomic locus><genomic profiling><genomic region><host response><humoral immunity deficiency><immune system response><immunoresponse><inflammatory environment><inflammatory milieu><insight><large cell Diffuse non-Hodgkin's lymphoma><loss of function mutation><monocyte><neutrophil><overexpress><overexpression><pathogen><permissiveness><premature><prematurity><preservation><programs><psychological defense mechanism><recruit><response><scRNA sequencing><scRNA-seq><single cell RNA-seq><single cell RNAseq><single cell expression profiling><single cell transcriptomic profiling><single-cell RNA sequencing><social role><transcription factor>
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Robbie B Mailliard

UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PITTSBURGH, PA

Good lead · 60/100
Likely hiring
Above-average budget
Active award
$637,792
FY 2026

Project Title

Antigen-specific ‘kick and kill’ of the latent HIV reservoir using dendritic cells

Grant Number:

5R01AI152655-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

11/5/2021

End Date:

10/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT The persistence of the latent viral reservoir remains a hurdle for the cure of chronic HIV infection. Finding an effective and non-toxic means to purge and expose the viral reservoir has been elusive and is considered a major barrier to the cure. Because of their pivotal role in the initiat...

Research Terms

<AIDS Virus><Acquired Immune Deficiency Syndrome Virus><Acquired Immunodeficiency Syndrome Virus><Affect><Antigenic Determinants><Antigens><Autologous><B7-H1><Binding><Binding Determinants><Blood monocyte><Bp50><Brazil><CD154><CD274><CD4 Cells><CD4 Positive T Lymphocytes><CD4 T cells><CD4 helper T cell><CD4 lymphocyte><CD4+ T-Lymphocyte><CD4-Positive Lymphocytes><CD40><CD40L><CD40LG><CDW40><CMV><Cancers><Cell Body><Cell Communication and Signaling><Cell Signaling><Cell-Mediated Lympholytic Cells><Cells><Cellular immunotherapy><Class I Genes><Class II Genes><Clinical Trials><Combined Modality Therapy><Cytolytic T-Cell><Cytomegalovirus><Cytotoxic T Cell><Cytotoxic T-Lymphocytes><Dendritic Cell Therapy><Dendritic Cells><Early-Stage Clinical Trials><Effector Cell><Epitopes><Evaluation><Event><Exposure to><Gene Modified><HCMV><HIV><HIV Infections><HIV intervention><HIV latency><HIV replication><HIV therapeutic><HIV therapy><HIV treatment><HIV viral infection><HIV viral replication><HIV virus infection><HIV-1 infection><HIV-1 intervention><HIV-1 replication><HIV-1 therapeutic><HIV-1 therapy><HIV-1 treatment><HIV-1 viral replication><HIV-1 virus replication><HLA Class II Genes><Human Immunodeficiency Virus therapy><Human Immunodeficiency Virus treatment><Human Immunodeficiency Viruses><Immune><Immune mediated therapy><Immunes><Immunity><Immunologically Directed Therapy><Immunotherapeutic agent><Immunotherapy><In Vitro><Individual><Infection by HIV-1><Infection from HIV-1><Infection of HIV-1><Interruption><Intracellular Communication and Signaling><Investigators><LAV-HTLV-III><Link><Lymphadenopathy-Associated Virus><Lymphatic cell><Lymphocyte><Lymphocytic><MGC9013><MHC Class I><MHC Class I Genes><MHC Class II><MHC Class II Genes><Malignant Neoplasms><Malignant Tumor><Marrow monocyte><Masks><Mediating><Molecular Interaction><Multimodal Therapy><Multimodal Treatment><PD-1 antibody><PD-1 inhibitors><PD-1/PD-L1><PD-1/PDL1><PD-L1><PD1 antibody><PD1 inhibitors><PD1-PD-L1><PD1/PD-L1><PD1/PDL1><PDL-1><Participant><Peptides><Phase 1 Clinical Trials><Phase I Clinical Trials><Production><Programmed Cell Death 1 Ligand 1><Programmed Death Ligand 1><Regulation><Research><Research Personnel><Researchers><Residual><Residual state><Role><Salivary Gland Viruses><Sampling><Signal Transduction><Signal Transduction Systems><Signaling><Site><T-Cell Subsets><T-Cells><T-Lymphocyte><T-Lymphocyte Subsets><T4 Cells><T4 Lymphocytes><TNFRSF5><TNFRSF5 gene><TNFSF5><TNFSF5 gene><TRAP Gene><Testing><The Multi-center AIDS Cohort Study><The Multicenter AIDS Cohort Study><Therapeutic><Translating><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><Universities><Veiled Cells><Viral><Viral Antigens><Viral Latency><Viral reservoir><Viremia><Virus Latency><Virus reservoir><Virus-HIV><aPD-1><aPD1><anti programmed cell death 1><anti programmed cell death protein 1 inhibitor><anti-PD-1><anti-PD-1 Ab><anti-PD-1 antibodies><anti-PD-1 inhibitors><anti-PD-1 monoclonal antibodies><anti-PD1><anti-PD1 Ab><anti-PD1 antibodies><anti-PD1 inhibitors><anti-PD1 monoclonal antibodies><anti-programmed cell death protein 1><anti-programmed cell death protein 1 antibodies><anti-programmed death-1 antibody><antiPD-1><antiretroviral therapy><antiretroviral treatment><asymptomatic HIV infection><biological signal transduction><cell-based immunotherapy><check point inhibition><checkpoint inhibition><chronic HIV infection><combination therapy><combined modality treatment><combined treatment><cytomegalovirus group><design><designing><gene modification><genetically modified><human immunodeficiency virus infection><human immunodeficiency virus replication><human immunodeficiency virus-1 replication><humanized mice><humanized mouse><immune cell therapy><immune check point inhibition><immune checkpoint inhibition><immune clearance><immune drugs><immune elimination><immune therapeutic approach><immune therapeutic interventions><immune therapeutic regimens><immune therapeutic strategy><immune therapy><immune-based therapeutics><immune-based therapies><immune-based treatments><immuno therapy><immunogen><immunogenic><immunologic therapeutics><immunotherapeutics><immunotherapy agent><in vivo><infected with HIV><infected with human immunodeficiency virus><killer T cell><latent HIV infection><latent HIV reservoir><latent HIV-1 reservoir><latent HIV1 reservoir><lymph cell><malignancy><memory CD4 T cell><memory CD4 T lymphocyte><monocyte><mouse model><multi-modal therapy><multi-modal treatment><murine model><neoplasm/cancer><novel><p50><phase I protocol><programmed cell death ligand 1><programmed cell death protein ligand 1><protein death-ligand 1><purge><purges><purging><response><social role><therapeutic evaluation><therapeutic target><therapeutic testing><thymus derived lymphocyte><treat HIV><treat Human Immunodeficiency Virus><viraemia><viral sepsis><virus antigen><virusemia><αPD-1><αPD1>
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JAMES FRANCIS MARKMANN

UNIVERSITY OF PENNSYLVANIA, PHILADELPHIA, PA

Good lead · 60/100
Likely hiring
Above-average budget
Active award
$617,410
FY 2026

Project Title

Mechanisms of action, optimization and application of Bregs

Grant Number:

5R01AI057851-20

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2006

End Date:

12/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY / ABSTRACT It has been suggested that the future of medicine rests in cell and gene therapy. While this assertion may be premature, it seems clear that these innovative therapies have extraordinary, paradigm shifting potential. For cell-based therapies, this is best exemplified by th...

Research Terms

<(TNF)-α><ARHGEF5><ARHGEF5 gene><Adoptive Transfer><Allergy><Anti-CD20 Antibody><Antibodies><Antigen Presentation><Antigen Targeting><Antigens><Area><Assay><Autoimmune Status><Autoimmunity><B blood cells><B cell><B cells><B-Cell Activation><B-Cell Deficiency><B-Cell Subsets><B-Cells><B-Lymphocyte Subsets><B-Lymphocytes><B-cell><B7-H1><Bioassay><Biological Assay><Biological Markers><Blood><Blood Reticuloendothelial System><Body Tissues><Bone Marrow><Bone Marrow Reticuloendothelial System><Bone-Derived Transforming Growth Factor><Bp50><CAR T cells><CAR modified T cells><CAR-T><CAR-Ts><CD25><CD274><CD40><CDW40><CSIF><CSIF-10><Cachectin><Cancers><Cell Body><Cell Communication><Cell Communication and Signaling><Cell Interaction><Cell Signaling><Cell Therapy><Cell Transplantation><Cell-to-Cell Interaction><Cells><Clinical Research><Clinical Study><Clinical Treatment Moab><Comparative Study><Critical Paths><Critical Pathways><Cytokine Synthesis Inhibitory Factor><DNA Therapy><Data><Dermatoplasties><Dermatoplasty><Development><Endowment><Engineering><Environment><Exhibits><Experimental Models><Flow Cytofluorometries><Flow Cytofluorometry><Flow Cytometry><Flow Microfluorimetry><Flow Microfluorometry><Funding><Future><GEF5><Gene Transfer Clinical><Generations><Genetic Intervention><Goals><Graft Rejection><Graft Survival><Hematologic Cancer><Hematologic Malignancies><Hematologic Neoplasms><Hematological Malignancies><Hematological Neoplasms><Hematological Tumor><Hematopoietic Cancer><IL-10><IL10><IL10A><IL2R><IL2RA><IL2RA gene><Immune Regulators><Immune response><Immunomodulation><Immunomodulators><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><In Vitro><Innovative Therapy><Interleukin 10 Precursor><Interleukin-10><Intracellular Communication and Signaling><Investigation><Islands of Langerhans Transplantation><Islands of Pancreas Transplantation><Islets of Langerhans Grafting><Islets of Langerhans Transplantation><Kidney Grafting><Kidney Transplantation><Kidney Transplants><Location><Lymphatic cell><Lymphocyte><Lymphocytic><MGC9013><Macrophage-Derived TNF><Malignant Hematologic Neoplasm><Malignant Neoplasms><Malignant Tumor><Medicine><Mice><Mice Mammals><Milk Growth Factor><Modeling><Monitor><Monoclonal Antibodies><Monocyte-Derived TNF><Murine><Mus><Ovalbumin><P60><PD-L1><PDL-1><Pancreatic Islets Transplantation><Pathway interactions><Phenotype><Platelet Transforming Growth Factor><Population><Process><Progenitor Cells><Programmed Cell Death 1 Ligand 1><Programmed Death Ligand 1><Property><Receptor Protein><Refractory><Regulatory T-Lymphocyte><Renal Grafting><Renal Transplantation><Renal Transplants><Rest><Role><Series><Signal Induction><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><Skin><Skin Transplantation><Specificity><T cell response><T cells for CAR><T-Cell Activation><T-Cell Proliferation><T-Cells><T-Lymphocyte><TCGFR><TGF B><TGF-beta><TGF-β><TGFbeta><TGFβ><TIM1><TLR protein><TNF><TNF A><TNF Alpha><TNF gene><TNF-α><TNFA><TNFRSF5><TNFRSF5 gene><TNFα><Technology><Therapeutic><Tissue Grafts><Tissue Transplantation><Tissues><Toll-Like Receptor Family Gene><Toll-like receptors><Transforming Growth Factor beta><Transforming Growth Factor-Beta Family Gene><Translations><Transplant Rejection><Transplantation><Transplantation Rejection><Transplantation Tolerance><Treg><Tumor Necrosis Factor><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><Tumor Necrosis Factor-alpha><Validation><Work><activate T cells><activated B cells><adaptive immune response><adaptive immunity><allograft rejection><anti-CD20><arm><autologous islet transplantation><bio-markers><biologic marker><biological signal transduction><biomarker><cell based intervention><cell mediated intervention><cell mediated therapies><cell-based therapeutic><cell-based therapy><cellular therapeutic><cellular therapy><cellular transplant><chimeric antigen T cell receptor><chimeric antigen receptor><chimeric antigen receptor (CAR) T cells><chimeric antigen receptor T><chimeric antigen receptor T cells><chimeric antigen receptor fusion protein T-cells><chimeric antigen receptor modified T cells><cytokine><deliver vaccines><develop a vaccine><develop vaccines><development of a vaccine><developmental><early clinical trial><early phase clinical trial><experiment><experimental research><experimental study><experiments><flow cytophotometry><gene repair therapy><gene therapy><gene-based therapy><genetic therapy><genomic therapy><hepatic allograft><host response><humoral immunity deficiency><immune modulation><immune modulators><immune regulation><immune suppression><immune suppressive activity><immune suppressive function><immune system response><immunogen><immunologic reactivity control><immunomodulatory><immunomodulatory molecules><immunoregulation><immunoregulator><immunoregulatory><immunoregulatory molecules><immunoresponse><immunosuppressive activity><immunosuppressive function><immunosuppressive response><in vivo><innovate><innovation><innovative><interest><islet><islet auto transplantation><islet beta cell transplantation><islet cell transplant><islet cell transplantation><islet transplantation><kidney allograft><kidney tx><lipid based nanoparticle><lipid nanoparticle><liver allograft><lymph cell><mAbs><mRNA Expression><mRNA lipid nano particle vaccine><mRNA-LNP based vaccine><mRNA-LNP combination vaccines><mRNA-LNP vaccines><malignancy><monoclonal Abs><neoplasm/cancer><novel><organ rejection><organ transplant rejection><p50><pathway><pharmacologic><premature><prematurity><prevent><preventing><programmed cell death ligand 1><programmed cell death protein ligand 1><protein death-ligand 1><receptor><regulatory T-cells><renal allograft><response><scRNA sequencing><scRNA-seq><single cell RNA-seq><single cell RNAseq><single cell expression profiling><single cell transcriptomic profiling><single-cell RNA sequencing><social role><standard of care><stem cells><thymus derived lymphocyte><tissue grafting><transcriptome profiling><transcriptomic profiling><translation><translational opportunities><translational potential><transplant><transplant model><vaccine delivery><vaccine development><validations>
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Mark E Burkard

UNIVERSITY OF IOWA, IOWA CITY, IA

Good lead · 58/100
Likely hiring
Large award
Team-scale grant
$2,502,881
FY 2025

Project Title

Cancer Center Support Grant

Grant Number:

5P30CA086862-25

Activity Code:

P30

Mechanism:

Research Centers

Agency:

NIH

Start Date:

7/14/2000

End Date:

3/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY/ABSTRACT Holden Comprehensive Cancer Center (HCCC) at the University of Iowa (UI) is the only NCI designated cancer center in the state of Iowa, a highly rural state that serves as the HCCC catchment area. The nearest Comprehensive Cancer Centers are approximately 200 miles away. The...

Research Terms

<Address><Agonist><Area><Basic Cancer Research><Basic Research><Basic Science><Biometrics><Biometry><Biostatistics><Business-Friendly Atmosphere><CCSG><Cancer Burden><Cancer Cause><Cancer Center><Cancer Center Support Grant><Cancer Control><Cancer Control Science><Cancer Etiology><Cancer Genes><Cancer Research Infrastructure><Cancer Treatment><Cancer-Promoting Gene><Cancers><Catchment Area><Clinic><Clinical><Clinical Investigator><Clinical Protocols><Clinical Research><Clinical Services><Clinical Study><Clinical Trials><Collaborations><Communications Media><Communities><Community Outreach><Comprehensive Cancer Center><DNA Damage Repair><DNA Repair><Diagnostic><Disparities><Disparity><Dose><Education><Educational aspects><Environment><Epidemiologic Research><Epidemiologic Studies><Epidemiological Studies><Epidemiology Research><Evaluation><Experimental Therapies><Flow Cytofluorometries><Flow Cytofluorometry><Flow Cytometry><Flow Microfluorimetry><Flow Microfluorometry><Forms of Communication><Free Radicals><Funding><Genomics><Germinoblastic Sarcoma><Germinoblastoma><Goals><Grant><HPV Vaccination><High Throughput Assay><Holden Comprehensive Cancer Center at the University of Iowa><Human Papilloma Virus Vaccination><Human Papillomavirus Vaccination><Image><Infrastructure><Institution><Intermediary Metabolism><Investigational Therapies><Investigational Treatments><Investigators><Iowa><Laboratories><Lymphoma><Malignant Lymphoma><Malignant Neoplasm Therapy><Malignant Neoplasm Treatment><Malignant Neoplasms><Malignant Tumor><Measures><Metabolic Processes><Metabolism><Microscopy><Mission><Molecular Epidemiology><Monitor><Morbidity><Morbidity - disease rate><NCI-Designated Cancer Center><National Cancer Burden><Obesity><Oncogenes><Pain><Painful><Pathway interactions><Peer Review><Persons><Population Research><Population Sciences><Population-based research><Population-level research><Process><Protocol><Protocols documentation><Publications><Publishing><Radiation><Research><Research Infrastructure><Research Personnel><Research Resources><Research Support><Researchers><Resource Sharing><Resources><Reticulolymphosarcoma><Rural><Science><Scientific Advances and Accomplishments><Scientific Publication><Scientist><Specialized Program of Research Excellence><Structure><TLR9 gene><TLR9 protein><TLR9 receptor><Teen><Teenagers><Testing><Training><Transforming Genes><Translating><Translational Research><Translational Science><Universities><Unscheduled DNA Synthesis><Viral Vector><adiposity><anti-cancer research><anti-cancer therapy><ascorbate><business-friendly environment><cancer epidemiology><cancer prevention><cancer research><cancer therapy><cancer-directed therapy><career><clinical practice><collaborative atmosphere><collaborative environment><college><collegiate><community advisory board><community advisory committee><community advisory panel><community engagement><conference><convention><corpulence><design><designing><early clinical trial><early phase clinical trial><engagement with communities><epidemiologic investigation><epidemiology study><evidence base><experimental therapeutic agents><experimental therapeutics><flow cytophotometry><fundamental research><high throughput screening><imaging><improved><innovate><innovation><innovative><interactive atmosphere><interactive environment><interdisciplinary atmosphere><interdisciplinary collaboration><interdisciplinary environment><malignancy><meeting><meetings><member><mortality><neoplasm/cancer><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><notch><notch protein><notch receptors><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><pathway><peer-group atmosphere><peer-group environment><pharmacologic><population based><programs><protocol development><recruit><rural locality><rural place><rural setting><rurality><scientific accomplishments><scientific advances><summit><symposia><symposium><teen years><teenage><theranostics><toll-like receptor 9><transdisciplinary collaboration><translation research><translational investigation>
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Jason Yustein

EMORY UNIVERSITY, ATLANTA, GA

Good lead · 58/100
Likely hiring
Solid budget
Recent
Active award
$424,298
FY 2026

Project Title

Modeling and targeting intrinsic and extrinsic features of Myc-driven Osteosarcoma

Grant Number:

5R01CA288967-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2025

End Date:

2/28/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

Osteosarcoma (OS) is the most common bone tumor in pediatric patients. While defining genetic mutations are rare for OS, somatic DNA copy number alterations (SCNA) are a hallmark of OS and are becoming a means towards categorizing this complex, heterogeneous disease. One such SCNA is amplification o...

Research Terms

<8q24><Aberrant Chromosome><Address><Adolescent><Adolescent Youth><Agonist><Anti-Cancer Agents><Antineoplastic Agents><Antineoplastic Drugs><Antineoplastics><Basal Transcription Factor><Basal transcription factor genes><Basic Mechanisms of SUMOylation><Biogenesis><Bioinformatics><Biologic Models><Biological Models><Bone Sarcoma><Bone Tumor><Bone neoplasms><Bp50><C-C CKR-1><C-C Chemokine Receptor Type 1><CC chemokine receptor 1><CC-CKR-1><CCR-1><CCR1><CCR1 gene><CCR1 receptors><CD40><CDW40><CKR-1><CMKBR1><CMKR1><CMKR1 Gene><Cancer Drug><Cancer Genes><Cancer-Promoting Gene><Cell Body><Cell Communication><Cell Communication and Signaling><Cell Cycle><Cell Division Cycle><Cell Function><Cell Interaction><Cell Line><Cell Physiology><Cell Process><Cell Signaling><Cell-to-Cell Interaction><CellLine><Cells><Cellular Function><Cellular Physiology><Cellular Process><Chemokine (C-C Motif) Receptor 1><Childhood Cancers><Childhood Neoplasm><Childhood Tumor><Chromosomal Aberrations><Chromosomal Abnormalities><Chromosomal Alterations><Chromosomal, Gene, or Protein Abnormality><Chromosome Aberrations><Chromosome Alterations><Chromosome Anomalies><Chromosome abnormality><Chromosomes><Code><Coding System><Combined Modality Therapy><Complex><Cytogenetic Aberrations><Cytogenetic Abnormalities><Cytogenetic or Molecular Genetic Abnormality><DNA><DNA copy number><DNA mutation><DNA-Dependent RNA Polymerase II><Data><Deoxyribonucleic Acid><Dependence><Development><Disease><Disorder><Functional RNA><GEM model><GEMM model><Gene Transcription><General Transcription Factor Gene><General Transcription Factors><Genes><Genetic><Genetic Abnormality><Genetic Change><Genetic Transcription><Genetic defect><Genetic mutation><Genetically Engineered Mouse><Goals><HM145><Human><Immune><Immune Regulators><Immune infiltrates><Immunes><Immunocompetent><Immunologic Model><Immunological Models><Immunomodulation><Immunomodulators><Impairment><Inflammatory Response><Intermediary Metabolism><Intracellular Communication and Signaling><Knowledge><LD78 Receptor><Ligands><Lung Diseases><Lung Neoplasms><Lung Tumor><MGC9013><MIP-1 Alpha-R><MIP-1Alpha-R><MIP1aR><Macrophage><Macrophage Inflammatory Protein-1 Alpha Receptor><Malignant Childhood Neoplasm><Malignant Childhood Tumor><Malignant Pediatric Neoplasm><Malignant Pediatric Tumor><Malignant childhood cancer><Mediating><Metabolic Processes><Metabolism><Metastasis><Metastasize><Metastatic Lesion><Metastatic Mass><Metastatic Neoplasm><Metastatic Tumor><Mice><Mice Mammals><Mission><Model System><Modeling><Modern Man><Molecular><Molecular Abnormality><Molecular Fingerprinting><Molecular Profiling><Multimodal Therapy><Multimodal Treatment><Murine><Mus><Mutation><Myelogenous><Myeloid><Myeloid Cells><Mφ><NIH><National Institutes of Health><Neoplasm Metastasis><Neoplastic Disease Chemotherapeutic Agents><Noncoding RNA><Nontranslated RNA><Oncogenes><Oncogenic><Origin of Life><Osseous Neoplasm><Osseous Sarcoma><Osseous Tumor><Osteogenic Sarcoma><Osteosarcoma><Outcome><PDX model><Pathway interactions><Patient derived xenograft><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Pediatric Neoplasm><Pediatric Tumor><Prognosis><Protein Inhibition><Proteins><Proteomics><Pulmonary Diseases><Pulmonary Disorder><Pulmonary Neoplasms><RANTES Receptor Gene><RANTES-R><RNA Expression><RNA Polymerase B><RNA Polymerase II><RNA Polymerase Inhibitor><Receptor Protein><Regimen><Regulation><Research Resources><Research Specimen><Resources><Role><SUMOylation><Sampling><Secondary Neoplasm><Secondary Tumor><Secondary to><Signal Transduction><Signal Transduction Systems><Signaling><Skeletal Sarcoma><Specimen><Strains Cell Lines><Subcellular Process><Subgroup><Sumoylation Pathway><Survival Rate><T-Cell Activation><T-Cells><T-Lymphocyte><TNFRSF5><TNFRSF5 gene><Therapeutic><Transcription><Transcription Factor Proto-Oncogene><Transcription factor genes><Transforming Genes><Transgenic Organisms><Translations><Treatment Efficacy><Treatment Protocols><Treatment Regimen><Treatment Schedule><Tumor Biology><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><Tumor-Specific Treatment Agents><United States National Institutes of Health><Untranslated RNA><Validation><activate T cells><alternative treatment><analysis pipeline><anti-cancer drug><bio-informatics pipeline><bioinformatics pipeline><biological signal transduction><c myc><c-myc Genes><cancer in a child><cancer in children><cancer metastasis><cancer microenvironment><candidate identification><check point inhibition><checkpoint inhibition><child patients><child with cancer><childhood malignancy><chromosomal defect><chromosome defect><cmyc><combination therapy><combinatorial><combined modality treatment><combined treatment><copy number alteration><cultured cell line><developmental><disease of the lung><disorder of the lung><gene manipulation><genetic manipulation><genetically engineered mouse model><genetically engineered murine model><genetically manipulate><genetically perturb><genome mutation><genomic aberrations><genomic data><genomic dataset><high risk><high-throughput drug screening><immune cell infiltrate><immune check point inhibition><immune checkpoint inhibition><immune competent><immune microenvironment><immune modulation><immune modulators><immune regulation><immunologic reactivity control><immunomodulatory><immunomodulatory molecules><immunoregulation><immunoregulator><immunoregulatory><immunoregulatory molecules><immunosuppressive microenvironment><immunosuppressive tumor microenvironment><inhibit protein><inhibit proteins><inhibitor><innovate><innovation><innovative><intervention efficacy><junction adhesion molecule><junctional adhesion molecule><juvenile><juvenile human><loss of function><lung disorder><molecular aberrations><molecular profile><molecular signature><molecular targeted therapeutics><molecular targeted therapies><molecular targeted treatment><multi-modal therapy><multi-modal treatment><noncoding><notch><notch protein><notch receptors><novel><osteochondrosarcoma><osteoid sarcoma><overexpress><overexpression><p50><pathway><patient derived xenograft model><patient oriented outcomes><patient subclass><patient subcluster><patient subgroups><patient subpopulations><patient subsets><patient subtypes><pediatric cancer><pediatric malignancy><pediatric patients><pharmacologic><primary bone cancer><primary bone tumor><protein inhibitions><public data base><public database><publicly accessible data base><publicly accessible database><publicly available data base><publicly available database><receptor><recruit><relapse risk><resistance to therapy><resistant to therapy><risk stratification><scRNA sequencing><scRNA-seq><single cell RNA-seq><single cell RNAseq><single cell expression profiling><single cell transcriptomic profiling><single-cell RNA sequencing><small molecule><small molecule therapeutics><social role><standard of care><stratify risk><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment><therapeutic candidate><therapeutic efficacy><therapeutic resistance><therapy efficacy><therapy resistant><thymus derived lymphocyte><trait><transcription factor><transcriptomics><transgenic><translation><translational study><treatment resistance><tumor><tumor cell metastasis><tumor immune microenvironment><tumor microenvironment><tumor-immune system interactions><tumors in children><v-myc Avian Myelocytomatosis Viral Oncogene Cellular Homolog><validations>
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JAMIE LYNN FELTON

INDIANA UNIVERSITY INDIANAPOLIS, INDIANAPOLIS, IN

Good lead · 56/100
Training-friendly
Very recent
Active award
Career award
$154,207
FY 2026

Project Title

Genetic and Metabolic Regulation of B Cell Function in Type 1 Diabetes

Grant Number:

1K08DK147614-01

Activity Code:

K08

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

5/1/2026

End Date:

4/30/2031

Why this may be worth a closer look

  • • Activity code is useful for trainees, fellows, or mentored roles.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

PROJECT SUMMARY/ABSTRACT This project is a Mentored Clinical Scientist Research Career Development Award (K08) application for Dr. Jamie Felton, an Assistant Professor of Pediatrics at the Indiana University School of Medicine. Dr. Felton completed clinical training in Pediatric Endocrinology and ha...

Research Terms

<APO2><Adoptive Transfer><Advanced Development><Alleles><Allelomorphs><Anti-CD3 Antibody><Antigen Presentation><Antigen-Antibody Complex><Assay><Autoantibodies><Autoimmune Diseases><Autoimmune Responses><Autoimmune Status><Autoimmunity><Award><B blood cells><B cell><B cell depletion therapy><B cell directed therapy><B cell targeted therapy><B cell therapies><B cell therapy><B cells><B-Cell Development><B-Cell Subsets><B-Cells><B-Lymphocyte Subsets><B-Lymphocytes><B-cell><BACH2><BACH2 gene><BTB and CNC Homology 2><Basic Leucine Zipper Transcription Factor 2><Basic Research><Basic Science><Beta Cell><Bioassay><Biological Assay><Bp50><Brittle Diabetes Mellitus><CD152><CD152 Antigen><CD152 Gene><CD25><CD40><CDW40><CTLA 4><CTLA-4 Gene><CTLA4><CTLA4 gene><CTLA4-TM><Candidate Disease Gene><Candidate Gene><Career Development Awards><Career Development Awards and Programs><Career Development Programs K-Series><Cell Communication><Cell Communication and Signaling><Cell Function><Cell Interaction><Cell Physiology><Cell Process><Cell Signaling><Cell-to-Cell Interaction><Cellular Function><Cellular Metabolic Process><Cellular Physiology><Cellular Process><Childhood><Chronic><Class II Genes><Clinical><Clinical Evaluation><Clinical Testing><Complex><Cord Blood><Cost of Illness><Cytotoxic T-Lymphocyte Protein 4><Cytotoxic T-Lymphocyte-Associated Antigen 4><Cytotoxic T-Lymphocyte-Associated Protein 4><Cytotoxic T-Lymphocyte-Associated Serine Esterase-4><DNA Molecular Biology><DR4><Data><Data Set><Death Receptor 4><Dedications><Development><Diabetes Mellitus><Diagnosis><Disease><Disease Costs><Disease Progression><Disease Resistance><Disorder><Endocrinology><Ensure><Fostering><Funding><Future><GWA study><GWAS><Gene Expression><Gene variant><Genetic><Genetic Risk><Genomics><Genotype><Glycolysis><Goals><HLA Class II Genes><HLA-BR><HLA-BR Antigens><HLA-D-Related Antigens><HLA-DR><HLA-DR Antigens><HLA-DR3><HLA-DR3 Antigen><HLA-MT><HLA-MT Antigens><Haplotypes><HuM291><Human><Humulin R><Hypoxia Inducible Factor><IDDM><IL2R><IL2RA><IL2RA gene><Immune Complex><Immune Targeting><Immune destruction><Immune mediated destruction><Immune mediated therapy><Immunologically Directed Therapy><Immunomodulation><Immunotherapy><Inbred NOD Mice><Indiana><Individual><Infant><Inflammatory><Influentials><Insulin><Insulin Cell><Insulin Secreting Cell><Insulin-Dependent Diabetes Mellitus><Intervention><Intracellular Communication and Signaling><Investigators><Juvenile-Onset Diabetes Mellitus><K-Awards><K-Series Research Career Programs><Ketosis-Prone Diabetes Mellitus><LYP gene><LYP protein><Link><Lymphoid Phosphatase><MGC9013><MGC9365><MHC Class II><MHC Class II Genes><Measures><Mentors><Metabolic><Metabolic Pathway><Metabolism and Endocrinology><Mission><MoAb HuM291><Modeling><Modern Man><Molecular><Molecular Biology><Molecular Immunology><Monitor><Monoclonal Antibody HuM291><NIDDK><NIH><NOD Mouse><NOR Mouse><National Institute of Diabetes and Digestive and Kidney Diseases><National Institutes of Health><Nature><Network Analysis><Non obese><Non-Obese Diabetes Resistant mouse><Non-Obese Diabetic Mice><Non-Receptor Type 22 Protein Tyrosine Phosphatase><Non-Receptor Type 8 Protein Tyrosine Phosphatase><Nonobese><Nonobese Diabetes Resistant mouse><Nonobese Diabetic Mouse><Novolin R><Outcome><PEP gene><PEP protein><PTPN22><PTPN22 gene><PTPN8><Participant><Pathogenicity><Pathway Analysis><Pathway interactions><Pediatrics><Pest-Domain Phosphatase><Phenotype><Physicians><Play><Preclinical data><Predisposition gene><Preventative intervention><Prevention><Protein Biosynthesis><Regular Insulin><Regulation><Regulator Genes><Research><Research Career Program><Research Personnel><Researchers><Ribosomal Peptide Biosynthesis><Ribosomal Protein Biosynthesis><Ribosomal Protein Synthesis><Risk><Risk-associated variant><Role><Scientist><Secondary to><Shapes><Sickness Cost><Signal Transduction><Signal Transduction Systems><Signaling><Subcellular Process><Sudden-Onset Diabetes Mellitus><Susceptibility Gene><T-Cells><T-Lymphocyte><T1 DM><T1 diabetes><T1D><T1DM><TCGFR><TNF-Related Apoptosis Inducing Ligand Receptor 1><TNF-related apoptosis-inducing ligand receptor 1><TNFRSF10A><TNFRSF10A gene><TNFRSF5><TNFRSF5 gene><TRAIL Receptor 1><TRAIL-R4><TRAILR-1><TRAILR1><TYK2><Techniques><Testing><Time><Training><Transcriptional Regulatory Elements><Translational Research><Translational Science><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><Tumor Necrosis Factor Receptor Superfamily, Member 10A><Type 1 Diabetes Mellitus><Type 1 diabetes><Type I Diabetes Mellitus><Umbilical Cord Blood><United States National Institutes of Health><Universities><Variant><Variation><allelic variant><autoimmune antibody><autoimmune beta cell destruction><autoimmune condition><autoimmune disorder><autoimmune islet destruction><autoimmunity disease><autoreactive B cell><autoreactive antibody><beta cell autoimmunity><biological signal transduction><candidate validation><career><cell metabolism><cellular metabaolism><clinical test><clinical training><cohort><cytokine><cytotoxic T-lymphocyte antigen 4><death receptor-4><design><designing><developmental><diabetes><diabetic><diabetogenic><disease model><disease risk><disorder model><disorder risk><enthusiastic atmosphere><enthusiastic environment><experience><fetal cord blood><genetic trans acting element><genetic variant><genome wide association><genome wide association scan><genome wide association study><genomewide association scan><genomewide association study><genomic variant><high risk><high risk group><high risk individual><high risk people><high risk population><immune modulation><immune regulation><immune therapeutic approach><immune therapeutic interventions><immune therapeutic regimens><immune therapeutic strategy><immune therapy><immune-based therapies><immune-based treatments><immuno therapy><immunologic reactivity control><immunological synapse><immunomodulatory><immunoregulation><immunoregulatory><insulin dependent diabetes><insulin dependent diabetes mellitus onset><insulin dependent type 1><insulin secretion><interest><intervention for prevention><islet autoantibody><islet autoimmunity><islet cell antibody><islet cell autoimmunity><juvenile diabetes><juvenile diabetes mellitus><ketosis prone diabetes><medical college><medical schools><metabolic profile><mouse model><murine model><non-obese diabetic (NOD) mice><nonobese diabetic (NOD) mice><p50><pathway><pediatric><pediatric department><preclinical findings><preclinical information><predisposing gene><preservation><prevention intervention><preventional intervention strategy><preventive intervention><professor><programs><protein synthesis><receptor TRAIL-4><regulatory gene><research clinical testing><resistance to disease><resistant disease><resistant to disease><response><risk allele><risk gene><risk genotype><risk loci><risk locus><risk variant><school of medicine><self reactive B cell><self reactive antibody><seroconversion><skills><social role><supportive atmosphere><supportive environment><susceptibility allele><susceptibility locus><susceptibility variant><therapeutic target><thymus derived lymphocyte><trans acting element><transcriptomics><translation research><translation strategy><translational approach><translational clinician><translational investigation><translational physician><translational strategy><tumor necrosis factor receptor superfamily member 10A><type 1 diabetes onset><type I diabetes><type one diabetes><whole genome association analysis><whole genome association study><β-cell><β-cells><βCell>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

GUADALUPE X AYALA

SAN DIEGO STATE UNIVERSITY, SAN DIEGO, CA

Good lead · 54/100
Large award
Recent
Active award
Team-scale grant
$4,539,536
FY 2026

Project Title

SDSU HealthLINK Center for Transdisciplinary Health Disparities Research

Grant Number:

5U54MD012397-08

Activity Code:

U54

Mechanism:

Research Centers

Agency:

NIH

Start Date:

9/11/2018

End Date:

3/31/2029

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.

Project Abstract

OVERALL – Project Summary The SDSU HealthLINK Center for Transdisciplinary Health Disparities Research (SDSU HealthLINK Center; Center) was established in 2018 to augment investigator, partner, and institutional capacity for minority health and health disparities (MHHD) research at SDSU and SDSU Imp...

Research Terms

<Address><Area><Behavioral><Biology><Biomedical Research><California><Clinical><Collaborations><Communities><Consent><Consultations><County><Coupled><Data><Data Science><Decrease health disparities><Development><Discipline><Doctor's Degree><Doctorate Degree><EXTMR><Educational workshop><Environment><Ethics><Evidence based practice><Extramural><Extramural Activities><Faculty><Fostering><Foundations><Funding><Generalized Growth><Goals><Grant><Growth><Health><Health Disparities Research><Health Inequity><Health Promotion><Health Services><Health Services Evaluation><Health Services Research><Health disparities related research><Health disparity mitigation><Health disparity reduction><Hispanic><Human Subject Research><Immigrant><Individual><Industry><Inequalities in Health><Inequities in Health><Infrastructure><Institution><Intervention><Investigators><Investments><Knowledge><LGBTQ><Latino><Lesbian Gay Bi-sexual Transgender Queer><Lesbian Gay Bisexual Transgender Queer><Letters><Lower health disparities><Medical Care Research><Methods><Mexico><Minority-Serving Institution><Mitigate health disparities><NCMHD><NIH><NIMHD><National Center on Minority Health and Health Disparities><National Institute of Minority Health and Health Disparities><National Institute on Minority Health and Health Disparities><National Institutes of Health><P50 Mechanism><P50 Program><Participant><Pilot Projects><Policies><Population><Population Research><Population-based research><Population-level research><Position><Positioning Attribute><Postdoc><Postdoctoral Fellow><Process><Progress Reports><Psychology><Public Health><R-Series Research Projects><R01 Mechanism><R01 Program><Reduce health disparities><Refugees><Research><Research Activity><Research Associate><Research Grants><Research Infrastructure><Research Personnel><Research Project Grants><Research Projects><Research Resources><Research Support><Research Training><Researchers><Resources><Rural><Rural Community><STEM Education><STEM knowledge><STEM research><Salutogenesis><Science><Science, Technology, Engineering and Math Education><Science, Technology, Engineering and Mathematics Education><Scientist><Services><Specialized Center><Strategic Planning><System><Tissue Growth><Training><Training Programs><Transcend><Translating><Translational Research><Translational Science><Translations><United States National Institutes of Health><Universities><Workshop><Writing><Youth><Youth 10-21><career><career development><community engaged participatory research><community engaged research><community engagement><community partnered research><community partners><community-based partners><community-engaged study><community-partnered study><consultation><cost><developmental><doctoral degree><engagement with communities><ethical><evidence base><health determinants><health disparities science><health equity promotion><health inequalities><health science research><implementation science><improved><innovate><innovation><innovative><institutional capacity><investigate population><low SES><low socio-economic position><low socio-economic status><low socioeconomic position><low socioeconomic status><member><minority health><minority health disparity><minority institution><ontogeny><pilot study><population investigation><population level investigation><population specific research><post-doc><post-doctoral><post-doctoral trainee><professor><programs><promote health equity><promoting health><recovery services><recovery support services><recruit><research associates><response><science, technology, engineering and math knowledge><science, technology, engineering and math research><science, technology, engineering and mathematics knowledge><science, technology, engineering and mathematics research><services research><skills><studies of populations><study of the population><study population><success><survey population><tool><translation><translation research><translational investigation><uptake><youth age>
View Full Project Details on NIH Reporter
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Kristen Jennifer Wells

SAN DIEGO STATE UNIVERSITY, SAN DIEGO, CA

Good lead · 54/100
Large award
Recent
Active award
Team-scale grant
$4,539,536
FY 2026

Project Title

SDSU HealthLINK Center for Transdisciplinary Health Disparities Research

Grant Number:

5U54MD012397-08

Activity Code:

U54

Mechanism:

Research Centers

Agency:

NIH

Start Date:

9/11/2018

End Date:

3/31/2029

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.

Project Abstract

OVERALL – Project Summary The SDSU HealthLINK Center for Transdisciplinary Health Disparities Research (SDSU HealthLINK Center; Center) was established in 2018 to augment investigator, partner, and institutional capacity for minority health and health disparities (MHHD) research at SDSU and SDSU Imp...

Research Terms

<Address><Area><Behavioral><Biology><Biomedical Research><California><Clinical><Collaborations><Communities><Consent><Consultations><County><Coupled><Data><Data Science><Decrease health disparities><Development><Discipline><Doctor's Degree><Doctorate Degree><EXTMR><Educational workshop><Environment><Ethics><Evidence based practice><Extramural><Extramural Activities><Faculty><Fostering><Foundations><Funding><Generalized Growth><Goals><Grant><Growth><Health><Health Disparities Research><Health Inequity><Health Promotion><Health Services><Health Services Evaluation><Health Services Research><Health disparities related research><Health disparity mitigation><Health disparity reduction><Hispanic><Human Subject Research><Immigrant><Individual><Industry><Inequalities in Health><Inequities in Health><Infrastructure><Institution><Intervention><Investigators><Investments><Knowledge><LGBTQ><Latino><Lesbian Gay Bi-sexual Transgender Queer><Lesbian Gay Bisexual Transgender Queer><Letters><Lower health disparities><Medical Care Research><Methods><Mexico><Minority-Serving Institution><Mitigate health disparities><NCMHD><NIH><NIMHD><National Center on Minority Health and Health Disparities><National Institute of Minority Health and Health Disparities><National Institute on Minority Health and Health Disparities><National Institutes of Health><P50 Mechanism><P50 Program><Participant><Pilot Projects><Policies><Population><Population Research><Population-based research><Population-level research><Position><Positioning Attribute><Postdoc><Postdoctoral Fellow><Process><Progress Reports><Psychology><Public Health><R-Series Research Projects><R01 Mechanism><R01 Program><Reduce health disparities><Refugees><Research><Research Activity><Research Associate><Research Grants><Research Infrastructure><Research Personnel><Research Project Grants><Research Projects><Research Resources><Research Support><Research Training><Researchers><Resources><Rural><Rural Community><STEM Education><STEM knowledge><STEM research><Salutogenesis><Science><Science, Technology, Engineering and Math Education><Science, Technology, Engineering and Mathematics Education><Scientist><Services><Specialized Center><Strategic Planning><System><Tissue Growth><Training><Training Programs><Transcend><Translating><Translational Research><Translational Science><Translations><United States National Institutes of Health><Universities><Workshop><Writing><Youth><Youth 10-21><career><career development><community engaged participatory research><community engaged research><community engagement><community partnered research><community partners><community-based partners><community-engaged study><community-partnered study><consultation><cost><developmental><doctoral degree><engagement with communities><ethical><evidence base><health determinants><health disparities science><health equity promotion><health inequalities><health science research><implementation science><improved><innovate><innovation><innovative><institutional capacity><investigate population><low SES><low socio-economic position><low socio-economic status><low socioeconomic position><low socioeconomic status><member><minority health><minority health disparity><minority institution><ontogeny><pilot study><population investigation><population level investigation><population specific research><post-doc><post-doctoral><post-doctoral trainee><professor><programs><promote health equity><promoting health><recovery services><recovery support services><recruit><research associates><response><science, technology, engineering and math knowledge><science, technology, engineering and math research><science, technology, engineering and mathematics knowledge><science, technology, engineering and mathematics research><services research><skills><studies of populations><study of the population><study population><success><survey population><tool><translation><translation research><translational investigation><uptake><youth age>
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Mei Yee Koh

UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH, SALT LAKE CITY, UT

Good lead · 54/100
Likely hiring
Above-average budget
Active award
$858,089
FY 2025

Project Title

A Role for the Novel HAF-NFkappaB Axis in Driving Obesity-Associated Liver Cancer

Grant Number:

4R01CA262262-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/1/2025

End Date:

8/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

Hepatocellular carcinoma (HCC), the predominant primary cancer of the liver, is 4th leading cause of cancer deaths, and the fastest growing malignancy in the US. Advanced-stage HCC remains largely incurable due to a dismal response rate (<20%) and therapeutic resistance. The current obesity epidemic...

Research Terms

<(TNF)-α><Address><Age><Albumins><Apoptosis><Apoptosis Pathway><Automobile Driving><Body Tissues><Bone-Derived Transforming Growth Factor><Bp50><CD40><CDW40><Cachectin><Cancer Cause><Cancer Etiology><Cancers><Carcinoma><Carcinoma Cell><Causality><Cell Body><Cell Communication and Signaling><Cell Death><Cell Death Induction><Cell Protection><Cell Signaling><Cells><Cessation of life><Complex><Cytoprotection><DNA Damage><DNA Injury><Death><Disease><Disease Progression><Disorder><Dysfunction><E3 Ligase><E3 Ubiquitin Ligase><Early Diagnosis><Epithelial cancer><Etiology><Fatty Liver><Female><Fibrosis><Functional disorder><Gene Transcription><Genes><Genetic Transcription><Genome Instability><Genomic Instability><Goals><HAF deficiency><Hepatic Cancer><Hepatic Cells><Hepatic Parenchymal Cell><Hepatitis><Hepatocarcinoma><Hepatocellular Carcinoma><Hepatocellular cancer><Hepatocyte><Hepatoma><Heterozygote><Human><Hypoxia><Hypoxia Pathway><Hypoxia and p53 in the Cardiovascular system><Hypoxic><In Vitro><Incidence><Infiltration><Inflammatory><Inflammatory Response><Injury to Liver><Intracellular Communication and Signaling><Kinases><Link><Liver><Liver Cells><Liver Cells Carcinoma><Liver Steatosis><Lymphotoxin><Lymphotoxin A><Lymphotoxin-alpha><Lymphotoxin-α><MAFLD><MGC9013><Macrophage-Derived TNF><Malignant Epithelial Cell><Malignant Epithelial Neoplasms><Malignant Epithelial Tumors><Malignant Neoplasms><Malignant Tumor><Malignant neoplasm of liver><Measures><Mediating><Mediator><Medical><Member 1 TNF Superfamily><Metabolic><Mice><Mice Mammals><Milk Growth Factor><Modern Man><Molecular><Monitor><Monocyte-Derived TNF><Murine><Mus><NASH><Neoplastic liver><Nuclear><Obesity><Obesity Epidemic><Outcome><Oxygen Deficiency><Pathogenesis><Pathway interactions><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Phosphorylation><Phosphotransferase Gene><Phosphotransferases><Physiologic><Physiological><Physiopathology><Platelet Transforming Growth Factor><Play><Prevalence><Primary Malignant Neoplasm of Liver><Primary carcinoma of the liver cells><Primary liver cancer><Prognostic Marker><Programmed Cell Death><Protein Phosphorylation><Proteins><RNA Expression><Role><Sampling><Severities><Short interfering RNA><Signal Transduction><Signal Transduction Systems><Signaling><Small Interfering RNA><Stress><TGF B><TGF-beta><TGF-β><TGFbeta><TGFβ><TNF><TNF A><TNF Alpha><TNF gene><TNF-b><TNF-beta><TNF-α><TNF-β><TNFA><TNFRSF5><TNFRSF5 gene><TNFSF1><TNFα><TNFβ><Testing><Time><Tissues><Transcription><Transfection><Transforming Growth Factor beta><Transforming Growth Factor-Beta Family Gene><Transphosphorylases><Tumor Necrosis Factor><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><Tumor Necrosis Factor-Beta><Tumor Necrosis Factor-alpha><Tumor Necrosis Factor-β><Tumor Suppressor Proteins><Ubiquitin Protein Ligase><Ubiquitin-Protein Ligase Complexes><Ubiquitin-Protein Ligase E3><Viral hepatitis><adiposity><ages><biological signal transduction><causation><corpulence><cytokine><cytoprotective><diagnostic approach><diagnostic strategy><dietary><disease causation><driving><early detection><effective therapy><effective treatment><epithelial carcinoma><fatty liver disease><hepatic body system><hepatic damage><hepatic inflammation><hepatic injury><hepatic organ system><hepatic steatosis><hepatitis virus infection><hepatosteatosis><heterozygosity><in vivo><inflamed liver><insight><knock-down><knockdown><liver cancer><liver carcinoma><liver damage><liver inflammation><liver injury><liver malignancy><male><malignancy><malignant liver tumor><metabolic-associated fatty liver disease><mortality><mouse model><murine model><necrocytosis><neoplasm/cancer><neoplastic><new diagnostics><new drug target><new druggable target><new pharmacotherapy target><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapeutic target><new therapy approaches><new therapy target><new treatment approach><new treatment strategy><next generation diagnostics><non-alcohol induced steatohepatitis><non-alcoholic steato-hepatitis><non-alcoholic steatohepatitis><nonalcoholic steato-hepatitis><nonalcoholic steatohepatitis><novel><novel diagnostics><novel drug target><novel druggable target><novel pharmacotherapy target><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapeutic target><novel therapy approach><novel therapy target><overexpress><overexpression><p50><p65><pathophysiology><pathway><patient oriented outcomes><potential biological marker><potential biomarker><predictive biological marker><predictive biomarkers><predictive marker><predictive molecular biomarker><prevent><preventing><prognostic biomarker><prognostic indicator><resistance to therapy><resistant to therapy><response><response to therapy><response to treatment><screening><screenings><siRNA><social role><therapeutic resistance><therapeutic response><therapeutic target><therapy resistant><therapy response><treatment resistance><treatment response><treatment responsiveness><treatment strategy><tumor suppressor><ubiquitin-protein ligase><♀><♂>
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PANKAJ B AGRAWAL

BOSTON CHILDREN'S HOSPITAL, BOSTON, MA

Good lead · 54/100
Likely hiring
Above-average budget
Active award
$828,367
FY 2025

Project Title

VIGOR: Virtual Genome Center for Infant Health

Grant Number:

5R01HG011798-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/24/2021

End Date:

6/30/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Genomic medicine has rapidly advanced in the past decade enabling earlier diagnosis and personalized treatment. However, only a few highly specialized centers in the US have the resources to take advantage of these advances in patient care. This has created a gap in access whereby pa...

Research Terms

<0-4 weeks old><Address><Adoption><All of Us Program><All of Us Research Program><All of Us Research Project><AoURP><Assess implementation><Caring><Clinical><Communication><Communities><Community Medicine><Community Networks><Complex><Consultations><Country><Data><Data Analyses><Data Analysis><Decreased Muscle Tone><Diagnosis><Diagnostic><Diagnostic Findings><Disease><Disorder><Early Diagnosis><Education><Educational aspects><Eligibility><Eligibility Determination><Enrollment><Evaluation><Family><Funding><Genetic><Genetic Diseases><Genome><Genomic medicine><Genomics><Goals><Health system><Hospitals><Hypomyotonia><Hypotonia><Implementation assessment><Infant Health><Infrastructure><Institutionalization><Intervention><Investigators><Knowledge><Medical><Medical center><Medicine><Mental Depression><Mental Health><Mental Hygiene><Metabolic Diseases><Metabolic Disorder><Modeling><Muscle Hypotony><Muscle Tone Poor><Muscle hypotonia><Muscular Hypotonia><NIH><National Institutes of Health><Neonatal Intensive Care Units><Newborn Infant><Newborn Intensive Care Units><Newborns><Outcome><P50 Mechanism><P50 Program><Patient Care><Patient Care Delivery><Patients><Penetration><Physicians><Probability><Protocol Screening><Provider><Psychological Health><Recommendation><Reporting><Research><Research Personnel><Research Resources><Researchers><Resources><Seizures><Signs and Symptoms><Specialized Center><Stress><Target Populations><Techniques><Testing><Therapeutic><Thesaurismosis><United States><United States National Institutes of Health><access differences><access gaps><age group><biomedical referral center><care for patients><care of patients><caring for patients><clinically actionable><community setting><congenital anomaly><consultation><data interpretation><depression><differences in access><early detection><enroll><evaluate implementation><evaluation of implementation><exome sequencing><exome-seq><experience><family support><gaps in access><gene testing><gene-based testing><genetic condition><genetic disorder><genetic testing><genome medicine><hypoimmunity><immune deficiency><immunodeficiency><implementation evaluation><implementation outcomes><implementation science><improved><innovate><innovation><innovative><insight><metabolism disorder><neonatal ICU><newborn child><newborn children><novel><personalization of treatment><personalized medicine><personalized therapy><personalized treatment><referral center><satisfaction><virtual>
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Margaret Graham Kemper Parker

BOSTON CHILDREN'S HOSPITAL, BOSTON, MA

Good lead · 54/100
Likely hiring
Above-average budget
Active award
$828,367
FY 2025

Project Title

VIGOR: Virtual Genome Center for Infant Health

Grant Number:

5R01HG011798-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/24/2021

End Date:

6/30/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Genomic medicine has rapidly advanced in the past decade enabling earlier diagnosis and personalized treatment. However, only a few highly specialized centers in the US have the resources to take advantage of these advances in patient care. This has created a gap in access whereby pa...

Research Terms

<0-4 weeks old><Address><Adoption><All of Us Program><All of Us Research Program><All of Us Research Project><AoURP><Assess implementation><Caring><Clinical><Communication><Communities><Community Medicine><Community Networks><Complex><Consultations><Country><Data><Data Analyses><Data Analysis><Decreased Muscle Tone><Diagnosis><Diagnostic><Diagnostic Findings><Disease><Disorder><Early Diagnosis><Education><Educational aspects><Eligibility><Eligibility Determination><Enrollment><Evaluation><Family><Funding><Genetic><Genetic Diseases><Genome><Genomic medicine><Genomics><Goals><Health system><Hospitals><Hypomyotonia><Hypotonia><Implementation assessment><Infant Health><Infrastructure><Institutionalization><Intervention><Investigators><Knowledge><Medical><Medical center><Medicine><Mental Depression><Mental Health><Mental Hygiene><Metabolic Diseases><Metabolic Disorder><Modeling><Muscle Hypotony><Muscle Tone Poor><Muscle hypotonia><Muscular Hypotonia><NIH><National Institutes of Health><Neonatal Intensive Care Units><Newborn Infant><Newborn Intensive Care Units><Newborns><Outcome><P50 Mechanism><P50 Program><Patient Care><Patient Care Delivery><Patients><Penetration><Physicians><Probability><Protocol Screening><Provider><Psychological Health><Recommendation><Reporting><Research><Research Personnel><Research Resources><Researchers><Resources><Seizures><Signs and Symptoms><Specialized Center><Stress><Target Populations><Techniques><Testing><Therapeutic><Thesaurismosis><United States><United States National Institutes of Health><access differences><access gaps><age group><biomedical referral center><care for patients><care of patients><caring for patients><clinically actionable><community setting><congenital anomaly><consultation><data interpretation><depression><differences in access><early detection><enroll><evaluate implementation><evaluation of implementation><exome sequencing><exome-seq><experience><family support><gaps in access><gene testing><gene-based testing><genetic condition><genetic disorder><genetic testing><genome medicine><hypoimmunity><immune deficiency><immunodeficiency><implementation evaluation><implementation outcomes><implementation science><improved><innovate><innovation><innovative><insight><metabolism disorder><neonatal ICU><newborn child><newborn children><novel><personalization of treatment><personalized medicine><personalized therapy><personalized treatment><referral center><satisfaction><virtual>
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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Timothy Wei-Wen Yu

BOSTON CHILDREN'S HOSPITAL, BOSTON, MA

Good lead · 54/100
Likely hiring
Above-average budget
Active award
$828,367
FY 2025

Project Title

VIGOR: Virtual Genome Center for Infant Health

Grant Number:

5R01HG011798-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/24/2021

End Date:

6/30/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Genomic medicine has rapidly advanced in the past decade enabling earlier diagnosis and personalized treatment. However, only a few highly specialized centers in the US have the resources to take advantage of these advances in patient care. This has created a gap in access whereby pa...

Research Terms

<0-4 weeks old><Address><Adoption><All of Us Program><All of Us Research Program><All of Us Research Project><AoURP><Assess implementation><Caring><Clinical><Communication><Communities><Community Medicine><Community Networks><Complex><Consultations><Country><Data><Data Analyses><Data Analysis><Decreased Muscle Tone><Diagnosis><Diagnostic><Diagnostic Findings><Disease><Disorder><Early Diagnosis><Education><Educational aspects><Eligibility><Eligibility Determination><Enrollment><Evaluation><Family><Funding><Genetic><Genetic Diseases><Genome><Genomic medicine><Genomics><Goals><Health system><Hospitals><Hypomyotonia><Hypotonia><Implementation assessment><Infant Health><Infrastructure><Institutionalization><Intervention><Investigators><Knowledge><Medical><Medical center><Medicine><Mental Depression><Mental Health><Mental Hygiene><Metabolic Diseases><Metabolic Disorder><Modeling><Muscle Hypotony><Muscle Tone Poor><Muscle hypotonia><Muscular Hypotonia><NIH><National Institutes of Health><Neonatal Intensive Care Units><Newborn Infant><Newborn Intensive Care Units><Newborns><Outcome><P50 Mechanism><P50 Program><Patient Care><Patient Care Delivery><Patients><Penetration><Physicians><Probability><Protocol Screening><Provider><Psychological Health><Recommendation><Reporting><Research><Research Personnel><Research Resources><Researchers><Resources><Seizures><Signs and Symptoms><Specialized Center><Stress><Target Populations><Techniques><Testing><Therapeutic><Thesaurismosis><United States><United States National Institutes of Health><access differences><access gaps><age group><biomedical referral center><care for patients><care of patients><caring for patients><clinically actionable><community setting><congenital anomaly><consultation><data interpretation><depression><differences in access><early detection><enroll><evaluate implementation><evaluation of implementation><exome sequencing><exome-seq><experience><family support><gaps in access><gene testing><gene-based testing><genetic condition><genetic disorder><genetic testing><genome medicine><hypoimmunity><immune deficiency><immunodeficiency><implementation evaluation><implementation outcomes><implementation science><improved><innovate><innovation><innovative><insight><metabolism disorder><neonatal ICU><newborn child><newborn children><novel><personalization of treatment><personalized medicine><personalized therapy><personalized treatment><referral center><satisfaction><virtual>
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Heather J Nuske

UNIVERSITY OF PENNSYLVANIA, PHILADELPHIA, PA

Good lead · 54/100
Likely hiring
Above-average budget
Active award
$793,736
FY 2025

Project Title

RCT of a Measurement Feedback App to Improve Data Quality, Supervision & Outcomes in Behavioral Health

Grant Number:

5R01MH136153-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/16/2024

End Date:

6/30/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT Decades of treatment studies demonstrate that youth with significant behavioral health needs make more progress when their treatment planning is informed by ongoing quantitative data collection (e.g., by changing treatment strategies, increasing therapy hours, and adding ser...

Research Terms

<0-11 years old><Active Follow-up><Attitude><Behavior><Behavior Conditioning Therapy><Behavior Modification><Behavior Therapy><Behavior Treatment><Behavioral><Behavioral Conditioning Therapy><Behavioral Modification><Behavioral Therapy><Behavioral Treatment><Caring><Child><Child Youth><Children (0-21)><Clinical><Communication><Communities><Complex><Conditioning Therapy><Cost Measures><Cost metrics><Data><Data Collection><Development><E-Mail><Electronic Mail><Email><Employee><Enrollment><Evidence based practice><Feedback><Fostering><Health Care><Health Care Technology><Health Technology><Hour><Hybrids><Interview><Jobs><Measurement><Measures><Mediator><Mental Health><Mental Hygiene><Methods><Modeling><Motivation><Nature><Neurodevelopmental Disorder><Neurological Development Disorder><Occupations><Out-patients><Outcome><Outpatients><Paper><Population Intervention><Position><Positioning Attribute><Process><Professional Positions><Psychological Factors><Psychological Health><Questionnaires><Randomization trial><Randomized><Reporting><Research Resources><Resources><Schools><Science><Self Efficacy><Services><Spinal Column><Spine><Supervision><Survey Instrument><Surveys><Symptoms><System><Testing><Therapeutic><Time><Vertebral column><Work><Youth><Youth 10-21><active followup><adolescent with ASD><adolescent with autism><adolescent with autism spectrum disorder><adolescents on the autism spectrum><autistic adolescent><autistic youth><backbone><behavior change><behavior intervention><behavioral economics><behavioral health><behavioral intervention><clinical care><community partners><community-based partners><cost measurement><data quality><data sharing><design><designing><developmental><digital data><digital health><effectiveness testing><electronic communication><electronic data><enroll><expectation><follow up><follow-up><followed up><followup><implementation strategy><implementation/effectiveness><improved><improved outcome><kids><neurodevelopmental disease><novel><pilot trial><population based intervention><population specific intervention><practical implementation><pragmatic implementation><primary outcome><programs><randomisation><randomization><randomized trial><randomly assigned><skill acquisition><skill development><skills><strategies for implementation><theories><therapy optimization><tool><treatment optimization><treatment planning><treatment strategy><trial design><user centered design><week trial><youngster><youth age><youth on the autism spectrum><youth with ASD><youth with autism><youth with autism spectrum disorder>
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Idan Shalev

PENNSYLVANIA STATE UNIVERSITY, THE, UNIVERSITY PARK, PA

Good lead · 54/100
Likely hiring
Above-average budget
Active award
$789,350
FY 2025

Project Title

Investigating Multiple Biological Mechanisms of Obesity in a High-Risk Pediatric Cohort with Confirmed Maltreatment

Grant Number:

1R01DK139357-01A1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

6/10/2025

End Date:

3/31/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY Childhood obesity, conceptualized as a “ticking time bomb”, is a prevalent condition with major adverse health consequences. A potent risk factor for childhood obesity is early-life adversity, such as child maltreatment (e.g. physical/sexual abuse and neglect). Our preliminary data f...

Research Terms

<0-11 years old><21+ years old><Acceleration><Adult><Adult Human><Age><Attention><Automobile Driving><BMI><BMI percentile><BMI z-score><Biologic Factor><Biological><Biological Aging><Biological Factors><Biology><Biometrics><Biometry><Biostatistics><Body mass index><Categories><Child><Child Abuse and Neglect><Child Health><Child Youth><Childhood><Childhood maltreatment><Children (0-21)><Clinical><Clinical Treatment><Collection><Complex><Computational Biology><Data><Data Analyses><Data Analysis><Data Collection><Economic Income><Economical Income><Effectiveness><Epigenetic age><Exposure to><Female><Funding><Future><Gene Expression><Gene Expression Monitoring><Gene Expression Pattern Analysis><Gene Expression Profiling><Generations><Genetic><Genetic Risk><Genomics><Goals><GrimAge clock><Hannum clock><Health><Horvath clock><Immune><Immune system><Immunes><Income><Individual><Intervention><Intervention Studies><Investigation><Ixodida><Knowledge><Length><Link><Long-term cohort><Longitudinal cohort><Measures><Metabolic><Metabolic Pathway><Minority><Modeling><Obesity><Obesity associated disease><Obesity related disease><Over weight><Overweight><Parents><Pathway interactions><Pediatric cohort><Personalized medical approach><PhenoAge clocks><Phenotype><Population><Prospective cohort><Puberty><Quetelet index><Race><Races><Reporting><Research><Risk><Risk Factors><Sampling><Severities><Sexual abuse><Skin><Stress><Survivors><Systems Biology><Testing><Ticks><Time><Transcript Expression Analyses><Transcript Expression Analysis><Trauma><Vulnerable Populations><Youth><Youth 10-21><abuse neglect><accelerated aging><accelerated biological age><accelerated biological aging><adiposity><adulthood><age acceleration><aged><ages><analyze gene expression><biologic><biological process of age><child adiposity><child maltreatment><child obesity><childhood adiposity><childhood obesity><clinical intervention><clinical practice><clinical therapy><cohort><computer biology><corpulence><data interpretation><design><designing><driving><early adversity><early childhood adversity><early life adversity><effective intervention><epigenetic age clocks><epigenetic clock><epigenetic molecular clocks><experience><follow up assessment><followup assessment><gene expression analysis><gene expression assay><global health><high BMI><high body mass index><high risk><incomes><individualized approach><innovate><innovation><innovative><insight><intervention program><intervention research><interventional research><interventional study><interventions research><kids><maltreated children><maltreatment><metabolic profile><metabolism measurement><metabolomics><metabonomics><methylation clock><mistreatment><multiomics><multiple data sets><multiple datasets><multiple omics><neglect and abuse><novel><obese children><obesity during childhood><obesity in children><obesity intervention><obesity prevention><obesity risk><obesity therapy><obesity treatment><panomics><parent><pathway><pediatric><pediatric obesity><personalized approach><precision approach><prevent obesity><programs><prospective><racial><racial background><racial origin><resilience><resilient><response><risk for obesity><risk of obesity><sex><sex abuse><sexually abused><stressor><tailored approach><telomere><transcriptional profiling><transcriptomics><trial regimen><trial treatment><vulnerable group><vulnerable individual><vulnerable people><youngster><youth age><♀>
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ZACKARY I CLEVELAND

CINCINNATI CHILDRENS HOSP MED CTR, CINCINNATI, OH

Good lead · 54/100
Likely hiring
Above-average budget
Active award
$789,104
FY 2025

Project Title

Imaging and Molecular Phenotyping of Cystic Fibrosis Lung Disease

Grant Number:

5R01HL151588-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/3/2021

End Date:

1/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

Cystic fibrosis (CF) is among the most common fatal genetic diseases in the U.S. and involves progressive lung function loss and structural remodeling, leading to lung transplant or death. Though life expectancy in CF patients has increased due to improved treatments, pathological changes still occu...

Research Terms

<12-20 years old><21+ years old><Acceleration><Adolescence><Adult><Adult Human><Affect><Age><Airway failure><Airway infections><Anti-Inflammatories><Anti-Inflammatory Agents><Anti-inflammatory><Asthma><Biological Markers><Blood><Blood Plasma><Blood Proteins><Blood Reticuloendothelial System><Blood Sample><Blood Serum><Blood specimen><Bronchi><Bronchial Asthma><Bronchiectasis><Bronchioalveolar Lavage><Bronchoalveolar Lavage><Bronchoalveolar Lavage Fluid><Bronchopulmonary Lavage><Bronchoscopy><CAT scan><CF Preschoolers><CF lung disease><CF patients><CFTR><CFTR Protein><COPD><CT X Ray><CT Xray><CT imaging><CT scan><Cessation of life><Children with CF><Chronic Obstruction Pulmonary Disease><Chronic Obstructive Lung Disease><Chronic Obstructive Pulmonary Disease><Clinical><Clinical Trials><Computed Tomography><Coupled><Cystic Fibrosis><Cystic Fibrosis Transmembrane Conductance Regulator><DNA mutation><Data><Data Analyses><Data Analysis><Death><Demographic Factors><Diagnosis><Disease><Disease Progression><Disorder><Dysfunction><Early Diagnosis><FEV1><FEV1%VC><Forced Expiratory Volume 1 Test><Forced Expiratory Volume in 1 Second><Functional disorder><Future><Genetic Change><Genetic Diseases><Genetic defect><Genetic mutation><Goals><Health><Heterogeneity><Image><Impairment><Individual><Infection><Inflammation><Intervention><Investigation><Knowledge><Lavage><Life><Life Expectancy><Liquid Chromatography><Liquid substance><Longitudinal CT><Lung><Lung Diseases><Lung Grafting><Lung Lavage><Lung Respiratory System><Lung Transplantation><Lung damage><MR Imaging><MR Tomography><MRI><MRIs><Magnetic Resonance Imaging><Mass Photometry/Spectrum Analysis><Mass Spectrometry><Mass Spectroscopy><Mass Spectrum><Mass Spectrum Analyses><Mass Spectrum Analysis><Measures><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Methods><Mission><Modeling><Molecular><Molecular Fingerprinting><Molecular Profiling><Monitor><Mucous body substance><Mucoviscidosis><Mucus><Mutation><NIH><NMR Imaging><NMR Tomography><National Institutes of Health><Nature><Nuclear Magnetic Resonance Imaging><Outcome><Outcome Measure><P50 Mechanism><P50 Program><PFT/FEV1><Pathologic><Pathology><Pathway interactions><Patients><Personalized medical approach><Physiopathology><Plasma><Plasma Serum><Proteomics><Public Health><Pulmonary Cystic Fibrosis><Pulmonary Diseases><Pulmonary Disorder><Pulmonary Function Test/Forced Expiratory Volume 1><Pulmonary Graft><Pulmonary Pathology><Pulmonary Transplant><Pulmonary Transplantation><Radiation><Reaction><Regulator Genes><Repeated CT><Research><Research Specimen><Resolution><Respiratory Failure><Respiratory Infections><Respiratory Tract Infections><Reticuloendothelial System, Serum, Plasma><Scanning><Sensitivity and Specificity><Sequential CT><Serum><Severity of illness><Specialized Center><Specimen><Spirometry><Structural defect><Structural malformation><Technology><Testing><Time><Tomodensitometry><Transcriptional Regulatory Elements><Translating><Translations><United States><United States National Institutes of Health><Visualization><Work><X-Ray CAT Scan><X-Ray Computed Tomography><X-Ray Computerized Tomography><Xray CAT scan><Xray Computed Tomography><Xray computerized tomography><Zeugmatography><adolescence (12-20)><adulthood><ages><airway remodeling><bio-markers><biologic marker><biomarker><bronchiolar alveolar lavage><bronchopulmonary lavage therapy><catscan><children with cystic fibrosis><chronic obstructive pulmonary disorder><cohort><computed axial tomography><computer tomography><computerized axial tomography><computerized tomography><customized therapy><customized treatment><cystic fibrosis lung><cystic fibrosis lung disease><cystic fibrosis patients><cystic fibrosis preschoolers><cystic fibrosis transmembrane regulator><data interpretation><decline in function><decline in functional status><disease of the lung><disease severity><disorder of the lung><early CF><early cystic fibrosis><early detection><evidence base><fluid><functional decline><functional loss><functional status decline><genetic condition><genetic disorder><genetic trans acting element><genome mutation><high risk><image guidance><image guided><image-based method><imaging><imaging method><imaging modality><improved><individualized approach><individualized medicine><individualized patient treatment><individualized therapeutic strategy><individualized therapy><individualized treatment><individuals with CF><individuals with cystic fibrosis><innovate><innovation><innovative><lavage therapy><liquid><loss of function><lung disorder><lung function><lung function decline><lung injury><lung pathology><lung transplant><measurable outcome><molecular phenotype><molecular profile><molecular signature><mucous><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><non-contrast CT><noncontrast CT><noncontrast computed tomography><novel><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><outcome measurement><pathophysiology><pathway><patient specific therapies><patient specific treatment><patients with CF><patients with cystic fibrosis><pediatric cystic fibrosis><personalized approach><precision approach><predictive biological marker><predictive biomarkers><predictive marker><predictive molecular biomarker><prevent><preventing><prognostic tool><prospective><pulmonary><pulmonary damage><pulmonary function><pulmonary function decline><pulmonary injury><pulmonary tissue damage><pulmonary tissue injury><reconstruction><regulatory gene><repeated computed tomography><resolutions><risk prediction algorithm><risk prediction model><serial CT><serial computed tomography><serial diagnostic computed tomography><specific biomarkers><structural abnormalities><structural anomalies><tailored approach><tailored medical treatment><tailored therapy><tailored treatment><tandem mass spectrometry><tool><trans acting element><translation><unique treatment><ventilation>
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Assem G Ziady

CINCINNATI CHILDRENS HOSP MED CTR, CINCINNATI, OH

Good lead · 54/100
Likely hiring
Above-average budget
Active award
$789,104
FY 2025

Project Title

Imaging and Molecular Phenotyping of Cystic Fibrosis Lung Disease

Grant Number:

5R01HL151588-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/3/2021

End Date:

1/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

Cystic fibrosis (CF) is among the most common fatal genetic diseases in the U.S. and involves progressive lung function loss and structural remodeling, leading to lung transplant or death. Though life expectancy in CF patients has increased due to improved treatments, pathological changes still occu...

Research Terms

<12-20 years old><21+ years old><Acceleration><Adolescence><Adult><Adult Human><Affect><Age><Airway failure><Airway infections><Anti-Inflammatories><Anti-Inflammatory Agents><Anti-inflammatory><Asthma><Biological Markers><Blood><Blood Plasma><Blood Proteins><Blood Reticuloendothelial System><Blood Sample><Blood Serum><Blood specimen><Bronchi><Bronchial Asthma><Bronchiectasis><Bronchioalveolar Lavage><Bronchoalveolar Lavage><Bronchoalveolar Lavage Fluid><Bronchopulmonary Lavage><Bronchoscopy><CAT scan><CF Preschoolers><CF lung disease><CF patients><CFTR><CFTR Protein><COPD><CT X Ray><CT Xray><CT imaging><CT scan><Cessation of life><Children with CF><Chronic Obstruction Pulmonary Disease><Chronic Obstructive Lung Disease><Chronic Obstructive Pulmonary Disease><Clinical><Clinical Trials><Computed Tomography><Coupled><Cystic Fibrosis><Cystic Fibrosis Transmembrane Conductance Regulator><DNA mutation><Data><Data Analyses><Data Analysis><Death><Demographic Factors><Diagnosis><Disease><Disease Progression><Disorder><Dysfunction><Early Diagnosis><FEV1><FEV1%VC><Forced Expiratory Volume 1 Test><Forced Expiratory Volume in 1 Second><Functional disorder><Future><Genetic Change><Genetic Diseases><Genetic defect><Genetic mutation><Goals><Health><Heterogeneity><Image><Impairment><Individual><Infection><Inflammation><Intervention><Investigation><Knowledge><Lavage><Life><Life Expectancy><Liquid Chromatography><Liquid substance><Longitudinal CT><Lung><Lung Diseases><Lung Grafting><Lung Lavage><Lung Respiratory System><Lung Transplantation><Lung damage><MR Imaging><MR Tomography><MRI><MRIs><Magnetic Resonance Imaging><Mass Photometry/Spectrum Analysis><Mass Spectrometry><Mass Spectroscopy><Mass Spectrum><Mass Spectrum Analyses><Mass Spectrum Analysis><Measures><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Methods><Mission><Modeling><Molecular><Molecular Fingerprinting><Molecular Profiling><Monitor><Mucous body substance><Mucoviscidosis><Mucus><Mutation><NIH><NMR Imaging><NMR Tomography><National Institutes of Health><Nature><Nuclear Magnetic Resonance Imaging><Outcome><Outcome Measure><P50 Mechanism><P50 Program><PFT/FEV1><Pathologic><Pathology><Pathway interactions><Patients><Personalized medical approach><Physiopathology><Plasma><Plasma Serum><Proteomics><Public Health><Pulmonary Cystic Fibrosis><Pulmonary Diseases><Pulmonary Disorder><Pulmonary Function Test/Forced Expiratory Volume 1><Pulmonary Graft><Pulmonary Pathology><Pulmonary Transplant><Pulmonary Transplantation><Radiation><Reaction><Regulator Genes><Repeated CT><Research><Research Specimen><Resolution><Respiratory Failure><Respiratory Infections><Respiratory Tract Infections><Reticuloendothelial System, Serum, Plasma><Scanning><Sensitivity and Specificity><Sequential CT><Serum><Severity of illness><Specialized Center><Specimen><Spirometry><Structural defect><Structural malformation><Technology><Testing><Time><Tomodensitometry><Transcriptional Regulatory Elements><Translating><Translations><United States><United States National Institutes of Health><Visualization><Work><X-Ray CAT Scan><X-Ray Computed Tomography><X-Ray Computerized Tomography><Xray CAT scan><Xray Computed Tomography><Xray computerized tomography><Zeugmatography><adolescence (12-20)><adulthood><ages><airway remodeling><bio-markers><biologic marker><biomarker><bronchiolar alveolar lavage><bronchopulmonary lavage therapy><catscan><children with cystic fibrosis><chronic obstructive pulmonary disorder><cohort><computed axial tomography><computer tomography><computerized axial tomography><computerized tomography><customized therapy><customized treatment><cystic fibrosis lung><cystic fibrosis lung disease><cystic fibrosis patients><cystic fibrosis preschoolers><cystic fibrosis transmembrane regulator><data interpretation><decline in function><decline in functional status><disease of the lung><disease severity><disorder of the lung><early CF><early cystic fibrosis><early detection><evidence base><fluid><functional decline><functional loss><functional status decline><genetic condition><genetic disorder><genetic trans acting element><genome mutation><high risk><image guidance><image guided><image-based method><imaging><imaging method><imaging modality><improved><individualized approach><individualized medicine><individualized patient treatment><individualized therapeutic strategy><individualized therapy><individualized treatment><individuals with CF><individuals with cystic fibrosis><innovate><innovation><innovative><lavage therapy><liquid><loss of function><lung disorder><lung function><lung function decline><lung injury><lung pathology><lung transplant><measurable outcome><molecular phenotype><molecular profile><molecular signature><mucous><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><non-contrast CT><noncontrast CT><noncontrast computed tomography><novel><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><outcome measurement><pathophysiology><pathway><patient specific therapies><patient specific treatment><patients with CF><patients with cystic fibrosis><pediatric cystic fibrosis><personalized approach><precision approach><predictive biological marker><predictive biomarkers><predictive marker><predictive molecular biomarker><prevent><preventing><prognostic tool><prospective><pulmonary><pulmonary damage><pulmonary function><pulmonary function decline><pulmonary injury><pulmonary tissue damage><pulmonary tissue injury><reconstruction><regulatory gene><repeated computed tomography><resolutions><risk prediction algorithm><risk prediction model><serial CT><serial computed tomography><serial diagnostic computed tomography><specific biomarkers><structural abnormalities><structural anomalies><tailored approach><tailored medical treatment><tailored therapy><tailored treatment><tandem mass spectrometry><tool><trans acting element><translation><unique treatment><ventilation>
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Eliver Ghosn

EMORY UNIVERSITY, ATLANTA, GA

Good lead · 54/100
Likely hiring
Above-average budget
Active award
$778,829
FY 2025

Project Title

Early Life B-cell and plasma cell development in the human Spleen: a new paradigm for lifelong immunity

Grant Number:

1R01AI182276-01A1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

6/2/2025

End Date:

5/31/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT: In ongoing experiments, we show that early-life antibody-secreting cells (ASCs), or plasma cells (PCs), appear spontaneously in the spleen, not the bone marrow (BM), before birth. The splenic ASCs develop from transcriptionally distinct fetal B-progenitors absent in adults...

Research Terms

<0-11 years old><21+ years old><2nd trimester><Ab response><Adult><Adult Human><Age><Anatomic Sites><Anatomic structures><Anatomy><Antibodies><Antibody Formation><Antibody Production><Antibody Repertoire><Antibody Response><Antibody Specificity><Antibody-Secreting Cells><Antigens><Autoantigens><Autoimmune Status><Autoimmunity><Autologous Antigens><B blood cells><B cell><B cell repertoire><B cells><B-Cell Activation><B-Cell Development><B-Cell Subsets><B-Cells><B-Lymphocyte Subsets><B-Lymphocytes><B-cell><Bacteria><Birth><Blood Plasma Cell><Blood Precursor Cell><Body Tissues><Bone Marrow><Bone Marrow Reticuloendothelial System><Bp50><CD40><CDW40><Cell Body><Cell Communication and Signaling><Cell Signaling><Cell Survival><Cell Viability><Cell secretion><Cells><Cellular Secretion><Child><Child Youth><Children (0-21)><Chronologic Fetal Maturity><Cytokine Signal Transduction><Cytokine Signaling><Data><Dependence><Development><Encapsulated><Fetal Age><Fetal Liver><Fetal Spleen><Future><Gene Transcription><Genes><Genetic><Genetic Transcription><Gestation><Gestational Age><Hematopoietic><Hematopoietic Progenitor Cells><Hematopoietic stem cells><Human><Humoral Immunities><Immune><Immune response><Immune system><Immunes><Immunity><Immunoglobulin-Secreting Cells><Individual><Infant><Infection><Intracellular Communication and Signaling><Knowledge><Life><Light><Liver><Lymphopoiesis><MGC9013><Mature B-Cell><Mature B-Lymphocyte><Memory><Metabolic><Metabolic Glycosylation><Mice><Mice Mammals><Midtrimester><Modeling><Modern Man><Molecular><Murine><Mus><Organ><Organism><Parturition><Phenotype><Photoradiation><Plasma Cells><Plasmacytes><Population><Pregnancy><Progenitor Cells><Property><RNA Expression><Second Pregnancy Trimester><Second Trimester><Self-Antigens><Shapes><Signal Transduction><Signal Transduction Systems><Signaling><Specificity><Spleen><Spleen Development><Spleen Reticuloendothelial System><TNFRSF5><TNFRSF5 gene><Testing><Tissues><Transcription><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><Vaccination><activated B cells><adaptive immunity><adulthood><ages><antibody biosynthesis><antibody-based immunity><biological signal transduction><blood cell progenitor><blood progenitor><blood stem cell><blood-forming stem cell><cell mediated immune response><cytokine><developmental><environmental change><experiment><experimental research><experimental study><experiments><fetal><glycosylation><hematopoietic progenitor><hematopoietic stem progenitor cell><hemopoietic><hemopoietic progenitor><hemopoietic stem cell><hepatic body system><hepatic organ system><host response><humanized mice><humanized mouse><hypoimmunity><immune deficiency><immune system function><immune system response><immunization strategy><immunodeficiency><immunogen><immunoglobulin biosynthesis><immunoresponse><in utero><insight><kids><leukemia><living system><lymphocytopoiesis><microbiome><mouse model><murine model><natural antibodies><p50><pathogen><plasma cell development><plasmocyte><prenatal><pressure><progenitor><programs><response><stem cells><unborn><vaccination strategy><youngster>
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Farbod Nicholas Rahaghi

BRIGHAM AND WOMEN'S HOSPITAL, BOSTON, MA

Good lead · 54/100
Likely hiring
Above-average budget
Active award
$757,154
FY 2025

Project Title

Classification and Prognostication in Pulmonary Thromboembolism Using Computed Tomography Image Analytics

Grant Number:

5R01HL164717-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/1/2022

End Date:

6/30/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

Project Summary Pulmonary thromboembolism remains a significant cause of morbidity and mortality in the western world. While many of the initial symptoms in acute pulmonary embolism (PE) resolves with appropriate treatment, there is increasing awareness of chronic impact of the disease ranging from ...

Research Terms

<Active Follow-up><Acute><Acute Disease><Arterial Obstruction><Arterial Occlusion><Artery Obstruction><Awareness><Blood Vessels><Breathlessness><CAT scan><CT X Ray><CT Xray><CT imaging><CT scan><Cardiac><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Cause of Death><Cessation of life><Chronic><Chronic Disease><Chronic Illness><Circulation><Classification><Clinical><Clinical Data><Clotting><Coagulation><Coagulation Process><Complex><Computed Tomography><Coupled><Data><Death><Development><Diagnosis><Diagnostic><Disease><Disorder><Distal><Dysfunction><Dyspnea><Embolism><Embolus><European><Evaluation><Evolution><Exercise><Functional disorder><Functional impairment><Future><Gases><General Hospitals><Heart><Heart Vascular><Heart failure><Hospitals><Image><Image Analyses><Image Analysis><Imaging Device><Imaging Instrument><Imaging Tool><Impairment><Individual><Intercept><Intervention><Lung><Lung Diseases><Lung Respiratory System><Massachusetts><Methods><Modeling><Morbidity><Morbidity - disease rate><Newly Diagnosed><Obstruction><Operative Procedures><Operative Surgical Procedures><Outcome><P50 Mechanism><P50 Program><Patients><Phenotype><Physiopathology><Prospective Studies><Pulmonary Circulation><Pulmonary Diseases><Pulmonary Disorder><Pulmonary Embolism><Pulmonary Hypertension><Pulmonary Thromboembolism><QOL><Quality of life><Registries><Reporting><Reproducibility><Residual><Residual state><Resolution><Right Ventricular Dysfunction><Right heart dysfunction><Right ventricle dysfunction><Right-sided heart dysfunction><Risk><Scanning><Selection for Treatments><Severities><Severity of illness><Specialized Center><Surgical><Surgical Interventions><Surgical Procedure><Symptoms><Systematics><Time><Tomodensitometry><United States><Universities><Vascular Diseases><Vascular Disorder><Western World><Woman><X-Ray CAT Scan><X-Ray Computed Tomography><X-Ray Computerized Tomography><Xray CAT scan><Xray Computed Tomography><Xray computerized tomography><active followup><acute disease/disorder><acute disorder><artery occlusion><biomedical referral center><blood vessel disorder><cardiac failure><catscan><chronic disorder><chronic thromboembolic pulmonary hypertension><circulatory system><clinical care><clinical decision-making><computed axial tomography><computer tomography><computerized axial tomography><computerized tomography><deep learning><deep learning method><deep learning strategy><developmental><disease classification><disease of the lung><disease severity><disorder classification><disorder of the lung><experience><follow up><follow up imaging><follow-up><followed up><followup><hemodynamics><image evaluation><image interpretation><image processing><image-based method><imaging><imaging method><imaging modality><improved><longitudinal imaging><lung disorder><lung pressure><mortality><non-contrast CT><noncontrast CT><noncontrast computed tomography><nosology><novel><outcome prediction><pathophysiology><predict responsiveness><predicting response><prognostication><pulmonary><pulmonary arterial hypertension><pulmonary artery hypertension><pulmonary pressure><quantitative imaging><referral center><resolutions><response to therapy><response to treatment><selection of treatment><serial imaging><surgery><surgery outcome><surgical outcome><therapeutic response><therapy response><therapy selection><treatment choice><treatment response><treatment responsiveness><treatment selection><vascular><vascular dysfunction><vasculopathy>
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Reza Nezafat

BETH ISRAEL DEACONESS MEDICAL CENTER, BOSTON, MA

Good lead · 54/100
Likely hiring
Above-average budget
Active award
$726,778
FY 2025

Project Title

Cardiopulmonary Exercise MRI in Heart Failure with Preserved Ejection Fraction

Grant Number:

5R01HL158077-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/1/2021

End Date:

8/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

Project Summary Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in the United States, with the prevalence of heart failure with preserved ejection fraction (HFpEF) rising every year. Currently, there is no single non-invasive diagnostic test for accurate diagnosis of HFp...

Research Terms

<Active Follow-up><Acute><Aorta><BNP Gene Product><BNP-32><Biological Markers><Blood Plasma><Blood Vessels><Brain Natriuretic Peptide-32><Brain natriuretic peptide><Breathing><Breathlessness><Cardiac><Cardiac Abnormalities><Cardiopulmonary><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Causality><Cessation of life><Clinical><Clinical Trials><Complex><Coronary><Data><Death><Dedications><Diagnosis><Diagnostic><Diagnostic Findings><Diagnostic Specificity><Diagnostic tests><Diastolic heart failure><Disease Outcome><Disease Progression><Dysfunction><Dyspnea><EFRAC><Early Diagnosis><Early Intervention><Ejection Fraction><Ergometry><Etiology><Evaluation><Exercise><Exercise Test><Exertion><Fats><Fatty acid glycerol esters><Functional disorder><Functional impairment><Goals><HF with preserved ejection fraction><HFpEF><Health><Heart><Heart Abnormalities><Heart Muscle tissue><Heart Vascular><Heart failure><Hospital Admission><Hospitalization><Image><Imaging Device><Imaging Instrument><Imaging Tool><Life><Lung><Lung Diseases><Lung Respiratory System><Lung symptom><MR Imaging><MR Tomography><MRI><MRI Scans><MRIs><Magnetic Resonance Imaging><Magnetic Resonance Imaging Scan><Measures><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Medical center><Medicine><Methods><Monitor><Morbidity><Morbidity - disease rate><Myocardial tissue><NMR Imaging><NMR Tomography><Natriuretic Factor-32><Nature><Nesiritide><Nuclear Magnetic Resonance Imaging><Obesity><Organ><Out-patients><Outcome><Outpatients><P50 Mechanism><P50 Program><Patient Recruitments><Patients><Performance><Phenotype><Physiologic><Physiological><Physiopathology><Plasma><Plasma Serum><Prevalence><Preventative care><Preventive care><Probability><Prognosis><Prospective Studies><Protocol><Protocols documentation><Pulmonary Diseases><Pulmonary Disorder><Pulmonary Edema><Pulmonary Ventilation><Pulmonary imaging><Reference Standards><Resistance><Respiratory Aspiration><Respiratory Inspiration><Rest><Reticuloendothelial System, Serum, Plasma><Risk><Role><Signs and Symptoms><Specialized Center><Stress><Structure><Supination><Symptoms><Syndrome><Technology><Testing><Time><Type-B Natriuretic Peptide><United States><Vasodilating Agent><Vasodilator Agents><Vasodilator Drugs><Vasodilators><Ventricular><Zeugmatography><accurate diagnosis><accurate diagnostics><active followup><adiposity><bio-markers><biologic marker><biomarker><brain Natriuretic factor><cardiac failure><cardiac imaging><cardiac scanning><cardiovascular disorder><cardiovascular health><cardiovascular risk><cardiovascular risk factor><causation><circulatory system><co-morbid><co-morbidity><comorbidity><corpulence><cost><diagnostic criteria><disease causation><disease of the lung><disorder of the lung><early detection><effective therapy><effective treatment><emerging epidemic><exercise intolerance><experience><follow up><follow-up><followed up><followup><heart failure and reduced ejection fraction><heart failure with preserved ejection fraction><heart failure with preserved systolic function><heart failure with reduced ejection fraction><heart imaging><heart scanning><hemodynamics><imaging><improved><innovate><innovation><innovative><insight><inspiration><longitudinal imaging><lung disorder><lung edema><lung imaging><lung scanning><mortality><new approaches><new drug treatments><new drugs><new epidemic><new pharmacological therapeutic><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapeutics><new therapy><new therapy approaches><new treatment approach><new treatment strategy><next generation therapeutics><non-invasive diagnosis><non-invasive diagnostic><non-invasive imaging><noninvasive diagnosis><noninvasive diagnostic><noninvasive imaging><novel><novel approaches><novel drug treatments><novel drugs><novel epidemic><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel strategies><novel strategy><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapeutics><novel therapy><novel therapy approach><participant recruitment><pathophysiology><patient prognosis><pharmacologic><physical impairment><preserved ejection fraction heart failure><prevent><preventing><prognostic><prohormone><pulmonary respiration><pulmonary symptom><resistant><response><serial imaging><social role><stressor><treatment strategy><vascular><vascular abnormality>
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ELFAR ADALSTEINSSON

BOSTON CHILDREN'S HOSPITAL, BOSTON, MA

Good lead · 54/100
Likely hiring
Above-average budget
Active award
$692,792
FY 2025

Project Title

Fetal MRI: robust self-driving brain acquisition and body movement quantification

Grant Number:

5R01EB032708-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/1/2022

End Date:

11/30/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ ABSTRACT Our premise is that the fetal stage of human brain development is the most dynamic, the most vulnerable and the most important for lifelong behavioral and cognitive function. As many neurological disorders have their genesis in fetal life, there is a need to accurately quan...

Research Terms

<3-D><3-Dimensional><3D><Address><Anatomic Sites><Anatomic structures><Anatomy><Archives><Artifacts><Automobile Driving><Behavior><Behavioral><Body part><Brain><Brain Nervous System><COVID-19><CV-19><Chronologic Fetal Maturity><Clinical><Clinical Research><Clinical Study><Collaborations><Collection><Communicable Diseases><Complex><Connectionist Models><ConvNet><Coronavirus Infectious Disease 2019><Data><Data Bases><Databases><Defect><Deposit><Deposition><Development><Diagnosis><Disease><Disorder><Echo-Planar Imaging><Echo-Planar Magnetic Resonance Imaging><Echoplanar Imaging><Echoplanar Magnetic Resonance Imaging><Ecological impact><Encephalon><Ensure><Environmental Exposure><Environmental Impact><Extremities><Eye><Eyeball><Fetal Age><Fetus><Gestation><Gestational Age><Head><Health><Human><Image><Imaging Device><Imaging Instrument><Imaging Tool><Infectious Diseases><Infectious Disorder><Intervention><Joints><Leg><Legs Paralysis><Lesion><Life><Limb structure><Limbs><Location><Lower Extremities Paralysis><Lower Limbs Paralysis><MR Imaging><MR Tomography><MRI><MRIs><Magnetic Resonance Imaging><Measures><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Modern Man><Morphologic artifacts><Motion><Movement><NMR Imaging><NMR Tomography><Nervous System Diseases><Nervous System Disorder><Nervous System Physiology><Network-based><Neural Network Models><Neural Network Simulation><Neurologic><Neurologic Disorders><Neurologic function><Neurological><Neurological Disorders><Neurological function><Non-Trunk><Nuclear Magnetic Resonance Imaging><Opiates><Opioid><Outcome><P50 Mechanism><P50 Program><Paraplegia><Pathology><Perceptrons><Performance><Phase><Planar Medical Imaging><Population Study><Position><Positioning Attribute><Pregnancy><Prospective Studies><Protocol><Protocols documentation><Resolution><Sampling><Scanning><Schistorrhachis><Series><Site><Slice><Specialized Center><Spina Bifida><Spinal><Spinal Dysraphia><Spinal Dysraphism><Stratification><Structure><Substance abuse problem><T2 imaging><T2 weighted image><T2 weighted imaging><Testing><Time><Training><Triage><Update><Zeugmatography><abuse of substances><body movement><brain MR imaging><brain MRI><brain abnormalities><brain magnetic resonance imaging><brain volume><cerebral MR imaging><cerebral MRI><cerebral magnetic resonance imaging><cleft spine><clinical relevance><clinically relevant><cognitive function><convolutional network><convolutional neural nets><convolutional neural network><coronavirus disease 2019><coronavirus disease-19><coronavirus infectious disease-19><data base><developmental><driving><fetal><foot><hydrocele spinalis><imaging><improved><malformation><maternal adiposity><maternal obesity><motor deficit><neonatal brain><nervous system function><neurological disease><novel><paraplegic><population-based study><population-level study><postnatal><prospective><rachischisis posterior><reconstruction><resolutions><response><sex><studies of populations><study of the population><substance abuse><success><three dimensional><tool><treatment center><ultrasound>
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Patricia Ellen Grant

BOSTON CHILDREN'S HOSPITAL, BOSTON, MA

Good lead · 54/100
Likely hiring
Above-average budget
Active award
$692,792
FY 2025

Project Title

Fetal MRI: robust self-driving brain acquisition and body movement quantification

Grant Number:

5R01EB032708-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/1/2022

End Date:

11/30/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ ABSTRACT Our premise is that the fetal stage of human brain development is the most dynamic, the most vulnerable and the most important for lifelong behavioral and cognitive function. As many neurological disorders have their genesis in fetal life, there is a need to accurately quan...

Research Terms

<3-D><3-Dimensional><3D><Address><Anatomic Sites><Anatomic structures><Anatomy><Archives><Artifacts><Automobile Driving><Behavior><Behavioral><Body part><Brain><Brain Nervous System><COVID-19><CV-19><Chronologic Fetal Maturity><Clinical><Clinical Research><Clinical Study><Collaborations><Collection><Communicable Diseases><Complex><Connectionist Models><ConvNet><Coronavirus Infectious Disease 2019><Data><Data Bases><Databases><Defect><Deposit><Deposition><Development><Diagnosis><Disease><Disorder><Echo-Planar Imaging><Echo-Planar Magnetic Resonance Imaging><Echoplanar Imaging><Echoplanar Magnetic Resonance Imaging><Ecological impact><Encephalon><Ensure><Environmental Exposure><Environmental Impact><Extremities><Eye><Eyeball><Fetal Age><Fetus><Gestation><Gestational Age><Head><Health><Human><Image><Imaging Device><Imaging Instrument><Imaging Tool><Infectious Diseases><Infectious Disorder><Intervention><Joints><Leg><Legs Paralysis><Lesion><Life><Limb structure><Limbs><Location><Lower Extremities Paralysis><Lower Limbs Paralysis><MR Imaging><MR Tomography><MRI><MRIs><Magnetic Resonance Imaging><Measures><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Modern Man><Morphologic artifacts><Motion><Movement><NMR Imaging><NMR Tomography><Nervous System Diseases><Nervous System Disorder><Nervous System Physiology><Network-based><Neural Network Models><Neural Network Simulation><Neurologic><Neurologic Disorders><Neurologic function><Neurological><Neurological Disorders><Neurological function><Non-Trunk><Nuclear Magnetic Resonance Imaging><Opiates><Opioid><Outcome><P50 Mechanism><P50 Program><Paraplegia><Pathology><Perceptrons><Performance><Phase><Planar Medical Imaging><Population Study><Position><Positioning Attribute><Pregnancy><Prospective Studies><Protocol><Protocols documentation><Resolution><Sampling><Scanning><Schistorrhachis><Series><Site><Slice><Specialized Center><Spina Bifida><Spinal><Spinal Dysraphia><Spinal Dysraphism><Stratification><Structure><Substance abuse problem><T2 imaging><T2 weighted image><T2 weighted imaging><Testing><Time><Training><Triage><Update><Zeugmatography><abuse of substances><body movement><brain MR imaging><brain MRI><brain abnormalities><brain magnetic resonance imaging><brain volume><cerebral MR imaging><cerebral MRI><cerebral magnetic resonance imaging><cleft spine><clinical relevance><clinically relevant><cognitive function><convolutional network><convolutional neural nets><convolutional neural network><coronavirus disease 2019><coronavirus disease-19><coronavirus infectious disease-19><data base><developmental><driving><fetal><foot><hydrocele spinalis><imaging><improved><malformation><maternal adiposity><maternal obesity><motor deficit><neonatal brain><nervous system function><neurological disease><novel><paraplegic><population-based study><population-level study><postnatal><prospective><rachischisis posterior><reconstruction><resolutions><response><sex><studies of populations><study of the population><substance abuse><success><three dimensional><tool><treatment center><ultrasound>
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Kristin A. Hogquist

UNIVERSITY OF MINNESOTA, MINNEAPOLIS, MN

Good lead · 54/100
Likely hiring
Above-average budget
Active award
$641,069
FY 2025

Project Title

TCR signaling in thymic selection: Role of innate immune activation

Grant Number:

5R01AI179749-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

7/1/2024

End Date:

5/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

Summary The thymus plays a critical role in preventing autoimmunity by deleting or inducing a Treg cell fate in thymocytes that react to self-antigens present in the thymus. But it is unclear how the thymus achieves tolerance to transiently expressed self-antigens, like those expressed in induced im...

Research Terms

<(IFN) α><(IFN)-α><(IFN)α><Adopted><Alferon><Antibody Response><Antigen Presentation><Antigen Presentation Pathway><Antigen Processing and Presentation><Antigen-Presenting Cells><Antigens><Apopain><Apoptosis-Related Cysteine Protease Caspase 3><Assay><Athymic Mice><Athymic Nude Mouse><Autoantibodies><Autoantigens><Autoimmune><Autoimmune Diseases><Autoimmune Status><Autoimmunity><Autologous Antigens><B blood cells><B cell><B cells><B-Cell Activation><B-Cell Deficiency><B-Cells><B-Lymphocytes><B-cell><BLR1><BLR1 gene><Bioassay><Biological Assay><Body Tissues><Bp50><CASP-3><CASP3><CASP3 gene><CD154><CD40><CD40L><CD40LG><CDW40><CPP-32><CPP32><CPP32 protein><CPP32B><CPP32beta><CXCR-5><CXCR5><Cell Body><Cell Communication and Signaling><Cell Count><Cell Number><Cell Signaling><Cells><Class Switching><Class Switchings><Cysteine Protease CPP32><Cysteine Protease CPP32 Gene><Data><Defect><Dendritic Cells><Development><Ensure><Environment><Failure><Gene Transcription><Genetic Transcription><Germinal Center><Human><IFN><IFN Alpha><IFN α><IFN-α><IFNa><IFNα><Immune><Immune Cell Activation><Immune response><Immunes><Immunize><Immunoglobulin Class Switching><Immunoglobulin Class Switchings><Immunoglobulin Isotype-Switch Recombination><Immunoglobulin Switch Recombination><Infection><Infiltration><Inflammation><Innate Immune Response><Interferon Alfa-n3><Interferon-α><Interferons><Intracellular Communication and Signaling><Isotype Switching><Isotype Switchings><Leukocyte Interferon><Licensing><Life><Lymphoblast Interferon><Lymphoblastoid Interferon><MDR15><MGC9013><Mice><Mice Mammals><Modern Man><Murine><Mus><Nude Mice><PARP Cleavage Protease><PARP Cleavage Protease Gene><Pathology><Pathway interactions><Peptides><Peripheral><Phenotype><Play><Property><Proteins><Publishing><RNA Expression><Reaction><Receptor Protein><Regulatory T-Lymphocyte><Reproducibility><Research><Role><SCA-1><SCA-1 Gene><SREBP Cleavage Activity 1><SREBP Cleavage Activity 1 Gene><Self Stimulation><Self-Antigens><Signal Transduction><Signal Transduction Systems><Signaling><Source><Structure of germinal center of lymph node><Switch Recombination><T cell receptor repertoire sequencing><T cell receptor sequencing><T-Cells><T-Lymphocyte><TCR repertoire sequencing><TCR sequencing><TCR-seq><TCRseq><TNFRSF5><TNFRSF5 gene><TNFSF5><TNFSF5 gene><TRAP Gene><Testing><Thymic epithelial cell><Thymus><Thymus Gland><Thymus Proper><Thymus Reticuloendothelial System><Tissues><Transcription><Treg><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><Upregulation><Veiled Cells><Wound Repair><Yama><Yama protein><accessory cell><activated B cells><autoimmune antibody><autoimmune condition><autoimmune disorder><autoimmune reactivity><autoimmunity disease><autoreactive antibody><autoreactivity><biological signal transduction><caspase-3><cysteine protease P32><cytokine><deep sequencing><developmental><gene product><host response><humoral immunity deficiency><immune activation><immune system response><immunogen><immunoresponse><neonatal mice><p50><pathway><prevent><preventing><receptor><reconstitute><reconstitution><regulatory T-cells><self reactive antibody><social role><thymocyte><thymus derived lymphocyte><wound healing><wound recovery><wound resolution>
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Matthew Stephen Block

MAYO CLINIC JACKSONVILLE, JACKSONVILLE, FL

Good lead · 54/100
Likely hiring
Above-average budget
Active award
$639,109
FY 2025

Project Title

A phase I/II study of combined therapy with Th17-inducing dendritic cells and pembrolizumab in patients with recurrent epithelial ovarian cancer

Grant Number:

5R01CA276313-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

7/1/2023

End Date:

6/30/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT Ovarian cancer (OC) causes ~14,000 deaths each year in the USA. While there have been advances in treatment, progression is common and cure rates are low. In recent years, several trials have been done testing immune checkpoint blockade (ICB), either alone or in combination with other agent...

Research Terms

<Ab-dependent cellular cytotoxicity><Active Follow-up><Adaptive Immune System><Address><Adult Folate Receptor 1><Adult Folate-Binding Protein><Adverse Experience><Adverse event><Anti-VEGF><Anti-VEGF Humanized Monoclonal Antibody><Anti-VEGF RhuMAb><Antibodies><Antibody Activation><Antigens><B blood cells><B cell><B cells><B-Cells><B-Lymphocytes><B-cell><B7-H1><Blood Eosinophil><Body Tissues><CD274><CSAID-Binding Protein 1><CSAID-Binding Protein 2><CSBP2><CTLA-8><CTLA-8 Gene><CTLA8><CTLA8 Gene><Cancer Cause><Cancer Etiology><Cancer Patient><Cancers><Cell Mediated Immunology><Cell-Mediated Immunity><Cellular Immunity><Cessation of life><Characteristics><Clinical><Clinical effectiveness><Combination Vaccines><Combined Modality Therapy><Combined Vaccines><Cytokine-Suppressive Antiinflammatory Drug-Binding Protein 1><Cytokine-Suppressive Antiinflammatory Drug-Binding protein 2><Cytotoxic T-Lymphocyte-Associated Antigen 8><Cytotoxic T-Lymphocyte-Associated Antigen 8 Gene><Cytotoxic T-Lymphocyte-Associated Serine Esterase 8><Cytotoxic T-Lymphocyte-Associated Serine Esterase 8 Gene><DNA mutation><Data><Death><Dendritic Cell Vaccine><Dendritic Cells><Development><Disease Progression><Disease remission><Early-Stage Clinical Trials><Eosinophilic Granulocyte><Eosinophilic Leukocyte><Epithelial ovarian cancer><Evaluable><Evaluable Disease><FOLR><FOLR1><FOLR1 gene><Folate Receptor Alpha><Funding><Genetic Change><Genetic defect><Genetic mutation><Goals><Grant><Human><Humoral Immunities><Hyperthermia><IL-15><IL-17><IL-17 Gene><IL-17A><IL-17A Gene><IL15><IL15 Protein><IL17><IL17 Protein><IL17 gene><IL17A><IL17A Gene><Immune response><Immune system><Immunity><Immunologic Tests><Immunological Tests><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><Induction Therapy><Innate Immune System><Interleukin 17 (Cytotoxic T-Lymphocyte-Associated Serine Esterase 8)><Interleukin 17 (Cytotoxic T-Lymphocyte-Associated Serine Esterase 8) Gene><Interleukin 17 Precursor><Interleukin 17 Precursor Gene><Interleukin-15><Interleukin-15 Precursor><Interleukin-17><Intraperitoneal Chemotherapy><Keytruda><MAPK Inhibitors><MAPK14><MAPK14 Mitogen-Activated Protein Kinase><MAPK14 gene><MGC9721><MOv18><Macrophage><Malignant Neoplasms><Malignant Ovarian Neoplasm><Malignant Ovarian Tumor><Malignant Tumor><Malignant Tumor of the Ovary><Malignant neoplasm of ovary><Marrow Eosinophil><Mice><Mice Mammals><Mitogen-Activated Protein Kinase 14><Mitogen-Activated Protein Kinase Inhibitor><MoAb VEGF><Modern Man><Monoclonal Antibody Anti-VEGF><Multimodal Therapy><Multimodal Treatment><Murine><Mus><Mutation><Mxi2><Myelogenous><Myeloid><Mφ><NEOADJ><Neoadjuvant><Neoadjuvant Therapy><Neoadjuvant Treatment><Outcome><Outcome Measure><Ovarian Cancer-Associated Antigen><Ovarian Tumor><Ovary Cancer><Ovary Neoplasms><Ovary Tumor><PARP Inhibitor><PARP-1 inhibitor><PARPi><PD-L1><PDL-1><Pathologic><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Phagocytes><Phagocytic Cell><Phase><Phase 1 Clinical Trials><Phase 1/2 Clinical Trial><Phase I Clinical Trials><Phase I/II Clinical Trial><Phenotype><Poly(ADP-ribose) Polymerase Inhibitor><Poly(ADP-ribose) polymerase 1 inhibitor><Production><Programmed Cell Death 1 Ligand 1><Programmed Death Ligand 1><Recombinant Humanized Anti-VEGF Monoclonal Antibody><Recombinant Humanized Monoclonal Antibody to Vascular Endothelial Growth Factor><Recurrence><Recurrent><Recurrent disease><Regulatory T-Lymphocyte><Relapsed Disease><Remission><Resistance><RhuMAb VEGF><SAPK2A><Safety><Stress-Activated Protein Kinase 2A><T cell infiltration><T-Cells><T-Lymphocyte><Therapeutically Targetable><Time><Tissues><Treg><Vaccinated><Vaccination><Vaccines><Veiled Cells><Woman><Work><acquired immune system><active followup><amebocyte><analytical tool><antibody dependent cell mediated cytotoxicity><antibody dependent cytotoxicity><antibody mediated cellular cytotoxicity><antibody-based immunity><antibody-dependent cell cytotoxicity><antibody-dependent cellular cytotoxicity><antibody-mediated cytotoxicity><bevacizumab><biomarker identification><cancer infiltrating T cells><cancer microenvironment><cancer progression><check point blockade><checkpoint blockade><clinical efficacy><clinical outcome assessment><combination therapy><combined modality treatment><combined treatment><dendritic cell vaccination><develop a vaccine><develop vaccines><development of a vaccine><developmental><eosinophil><follow up><follow-up><followed up><followup><genome mutation><host response><identification of biomarkers><identification of new biomarkers><immune check point><immune check point blockade><immune checkpoint><immune checkpoint blockade><immune microenvironment><immune suppression><immune suppressive activity><immune suppressive function><immune system response><immunecheckpoint><immunogen><immunoresponse><immunosuppressive activity><immunosuppressive function><immunosuppressive microenvironment><immunosuppressive response><immunosuppressive tumor microenvironment><improved><induction therapies><intervention design><intraperitoneal therapy><malignancy><marker identification><measurable outcome><mouse model><multi-modal therapy><multi-modal treatment><murine model><neo-antigen><neo-epitopes><neoantigens><neoepitopes><neoplasm progression><neoplasm/cancer><neoplastic progression><novel><objective response rate><outcome measurement><ovarian cancer><ovarian neoplasm><p38><p38 MAP Kinase><p38 MAPK Gene><p38 Mitogen Activated Protein Kinase><p38 Protein Kinase><p38 SAPK><p38-Alpha><p38Alpha><patient oriented outcomes><patient profile><pembrolizumab><phase I protocol><pre-clinical><pre-clinical study><preclinical><preclinical study><prevent><preventing><primary outcome><profiles in patients><prognostic ability><prognostic power><prognostic utility><prognostic value><programmed cell death ligand 1><programmed cell death protein ligand 1><programs><protein death-ligand 1><recruit><regulatory T-cells><resistance mechanism><resistance to therapy><resistant><resistant mechanism><resistant to therapy><response><response biomarker><response markers><response to therapy><response to treatment><rhuMabVEGF><standard of care><success><therapeutic resistance><therapeutic response><therapeutically effective><therapy design><therapy resistant><therapy response><thymus derived lymphocyte><trafficking><treatment design><treatment resistance><treatment response><treatment responsiveness><tumor><tumor immune microenvironment><tumor infiltrating T cells><tumor microenvironment><tumor progression><tumor-immune system interactions><vaccine development>
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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Keith L. Knutson

MAYO CLINIC JACKSONVILLE, JACKSONVILLE, FL

Good lead · 54/100
Likely hiring
Above-average budget
Active award
$639,109
FY 2025

Project Title

A phase I/II study of combined therapy with Th17-inducing dendritic cells and pembrolizumab in patients with recurrent epithelial ovarian cancer

Grant Number:

5R01CA276313-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

7/1/2023

End Date:

6/30/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT Ovarian cancer (OC) causes ~14,000 deaths each year in the USA. While there have been advances in treatment, progression is common and cure rates are low. In recent years, several trials have been done testing immune checkpoint blockade (ICB), either alone or in combination with other agent...

Research Terms

<Ab-dependent cellular cytotoxicity><Active Follow-up><Adaptive Immune System><Address><Adult Folate Receptor 1><Adult Folate-Binding Protein><Adverse Experience><Adverse event><Anti-VEGF><Anti-VEGF Humanized Monoclonal Antibody><Anti-VEGF RhuMAb><Antibodies><Antibody Activation><Antigens><B blood cells><B cell><B cells><B-Cells><B-Lymphocytes><B-cell><B7-H1><Blood Eosinophil><Body Tissues><CD274><CSAID-Binding Protein 1><CSAID-Binding Protein 2><CSBP2><CTLA-8><CTLA-8 Gene><CTLA8><CTLA8 Gene><Cancer Cause><Cancer Etiology><Cancer Patient><Cancers><Cell Mediated Immunology><Cell-Mediated Immunity><Cellular Immunity><Cessation of life><Characteristics><Clinical><Clinical effectiveness><Combination Vaccines><Combined Modality Therapy><Combined Vaccines><Cytokine-Suppressive Antiinflammatory Drug-Binding Protein 1><Cytokine-Suppressive Antiinflammatory Drug-Binding protein 2><Cytotoxic T-Lymphocyte-Associated Antigen 8><Cytotoxic T-Lymphocyte-Associated Antigen 8 Gene><Cytotoxic T-Lymphocyte-Associated Serine Esterase 8><Cytotoxic T-Lymphocyte-Associated Serine Esterase 8 Gene><DNA mutation><Data><Death><Dendritic Cell Vaccine><Dendritic Cells><Development><Disease Progression><Disease remission><Early-Stage Clinical Trials><Eosinophilic Granulocyte><Eosinophilic Leukocyte><Epithelial ovarian cancer><Evaluable><Evaluable Disease><FOLR><FOLR1><FOLR1 gene><Folate Receptor Alpha><Funding><Genetic Change><Genetic defect><Genetic mutation><Goals><Grant><Human><Humoral Immunities><Hyperthermia><IL-15><IL-17><IL-17 Gene><IL-17A><IL-17A Gene><IL15><IL15 Protein><IL17><IL17 Protein><IL17 gene><IL17A><IL17A Gene><Immune response><Immune system><Immunity><Immunologic Tests><Immunological Tests><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><Induction Therapy><Innate Immune System><Interleukin 17 (Cytotoxic T-Lymphocyte-Associated Serine Esterase 8)><Interleukin 17 (Cytotoxic T-Lymphocyte-Associated Serine Esterase 8) Gene><Interleukin 17 Precursor><Interleukin 17 Precursor Gene><Interleukin-15><Interleukin-15 Precursor><Interleukin-17><Intraperitoneal Chemotherapy><Keytruda><MAPK Inhibitors><MAPK14><MAPK14 Mitogen-Activated Protein Kinase><MAPK14 gene><MGC9721><MOv18><Macrophage><Malignant Neoplasms><Malignant Ovarian Neoplasm><Malignant Ovarian Tumor><Malignant Tumor><Malignant Tumor of the Ovary><Malignant neoplasm of ovary><Marrow Eosinophil><Mice><Mice Mammals><Mitogen-Activated Protein Kinase 14><Mitogen-Activated Protein Kinase Inhibitor><MoAb VEGF><Modern Man><Monoclonal Antibody Anti-VEGF><Multimodal Therapy><Multimodal Treatment><Murine><Mus><Mutation><Mxi2><Myelogenous><Myeloid><Mφ><NEOADJ><Neoadjuvant><Neoadjuvant Therapy><Neoadjuvant Treatment><Outcome><Outcome Measure><Ovarian Cancer-Associated Antigen><Ovarian Tumor><Ovary Cancer><Ovary Neoplasms><Ovary Tumor><PARP Inhibitor><PARP-1 inhibitor><PARPi><PD-L1><PDL-1><Pathologic><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Phagocytes><Phagocytic Cell><Phase><Phase 1 Clinical Trials><Phase 1/2 Clinical Trial><Phase I Clinical Trials><Phase I/II Clinical Trial><Phenotype><Poly(ADP-ribose) Polymerase Inhibitor><Poly(ADP-ribose) polymerase 1 inhibitor><Production><Programmed Cell Death 1 Ligand 1><Programmed Death Ligand 1><Recombinant Humanized Anti-VEGF Monoclonal Antibody><Recombinant Humanized Monoclonal Antibody to Vascular Endothelial Growth Factor><Recurrence><Recurrent><Recurrent disease><Regulatory T-Lymphocyte><Relapsed Disease><Remission><Resistance><RhuMAb VEGF><SAPK2A><Safety><Stress-Activated Protein Kinase 2A><T cell infiltration><T-Cells><T-Lymphocyte><Therapeutically Targetable><Time><Tissues><Treg><Vaccinated><Vaccination><Vaccines><Veiled Cells><Woman><Work><acquired immune system><active followup><amebocyte><analytical tool><antibody dependent cell mediated cytotoxicity><antibody dependent cytotoxicity><antibody mediated cellular cytotoxicity><antibody-based immunity><antibody-dependent cell cytotoxicity><antibody-dependent cellular cytotoxicity><antibody-mediated cytotoxicity><bevacizumab><biomarker identification><cancer infiltrating T cells><cancer microenvironment><cancer progression><check point blockade><checkpoint blockade><clinical efficacy><clinical outcome assessment><combination therapy><combined modality treatment><combined treatment><dendritic cell vaccination><develop a vaccine><develop vaccines><development of a vaccine><developmental><eosinophil><follow up><follow-up><followed up><followup><genome mutation><host response><identification of biomarkers><identification of new biomarkers><immune check point><immune check point blockade><immune checkpoint><immune checkpoint blockade><immune microenvironment><immune suppression><immune suppressive activity><immune suppressive function><immune system response><immunecheckpoint><immunogen><immunoresponse><immunosuppressive activity><immunosuppressive function><immunosuppressive microenvironment><immunosuppressive response><immunosuppressive tumor microenvironment><improved><induction therapies><intervention design><intraperitoneal therapy><malignancy><marker identification><measurable outcome><mouse model><multi-modal therapy><multi-modal treatment><murine model><neo-antigen><neo-epitopes><neoantigens><neoepitopes><neoplasm progression><neoplasm/cancer><neoplastic progression><novel><objective response rate><outcome measurement><ovarian cancer><ovarian neoplasm><p38><p38 MAP Kinase><p38 MAPK Gene><p38 Mitogen Activated Protein Kinase><p38 Protein Kinase><p38 SAPK><p38-Alpha><p38Alpha><patient oriented outcomes><patient profile><pembrolizumab><phase I protocol><pre-clinical><pre-clinical study><preclinical><preclinical study><prevent><preventing><primary outcome><profiles in patients><prognostic ability><prognostic power><prognostic utility><prognostic value><programmed cell death ligand 1><programmed cell death protein ligand 1><programs><protein death-ligand 1><recruit><regulatory T-cells><resistance mechanism><resistance to therapy><resistant><resistant mechanism><resistant to therapy><response><response biomarker><response markers><response to therapy><response to treatment><rhuMabVEGF><standard of care><success><therapeutic resistance><therapeutic response><therapeutically effective><therapy design><therapy resistant><therapy response><thymus derived lymphocyte><trafficking><treatment design><treatment resistance><treatment response><treatment responsiveness><tumor><tumor immune microenvironment><tumor infiltrating T cells><tumor microenvironment><tumor progression><tumor-immune system interactions><vaccine development>
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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Koushik Roy

UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH, SALT LAKE CITY, UT

Good lead · 54/100
Likely hiring
Above-average budget
Active award
$625,348
FY 2025

Project Title

Gene regulatory network of memory B cell and long-lived plasma cell differentiation

Grant Number:

1R01AI186945-01A1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

7/3/2025

End Date:

6/30/2030

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

Abstract The generation of long-lasting humoral immunity is the purpose of almost all vaccines. Long-lasting humoral immunity is mediated through antibodies produced by plasma cells (PCs) and memory B cells (MBCs). Despite the outstanding success of vaccinations overall, many clinical and experiment...

Research Terms

<7S Gamma Globulin><Affinity><Antibodies><Antibody Affinity><Antibody-Producing Cells><Antigens><B Cell Proliferation><B blood cells><B cell><B cell receptor><B cells><B-Cell Antigen Receptor><B-Cells><B-Lymphocytes><B-cell><Binding><Bioavailability><Biological Availability><Blood Plasma Cell><Bp50><CD40><CDW40><Cell Body><Cell Communication and Signaling><Cell Differentiation><Cell Differentiation process><Cell Signaling><Cell Surface Receptors><Cell Survival><Cell Viability><Cells><Clinical><Compensation><Data><Decision Making><Development><Disease><Disorder><Drug Therapy><Effectiveness><Fluorescence><Generations><Genes><Germinal Center><Grippe><Hemagglutinin><Humoral Immunities><I-kappa B><I-kappa B Proteins><IKB><Ig Somatic Hypermutation><IgG><Immune Regulators><Immunity><Immunize><Immunoglobulin Enhancer-Binding Protein><Immunoglobulin G><Immunoglobulin Somatic Hypermutation><Immunoglobulin-Producing Cells><Immunomodulators><Infection><Infection prevention><Influenza><Influenza Vaccines><Influenza Virus><Intracellular Communication and Signaling><KO mice><Knock-out Mice><Knockout Mice><Knowledge><Laboratories><LoxP-flanked allele><MGC9013><Measures><Mediating><Memory B Cell><Memory B-Lymphocyte><Mice><Mice Mammals><Mission><Modeling><Molecular><Molecular Interaction><Murine><Mus><NF-Kappa B Inhibitor><NF-kB><NF-kappa B><NF-kappaB><NFKB><NFKB Inhibitor><NIH><National Institutes of Health><Nuclear Factor kappa B><Nuclear Transcription Factor NF-kB><Null Mouse><Pharmacological Treatment><Pharmacotherapy><Phenotype><Physiologic><Physiologic Availability><Physiological><Plasma Cells><Plasmacytes><Prevent infection><Process><Public Health><Receptor Signaling><Regulation><Reporter><Research><Role><Signal Induction><Signal Transduction><Signal Transduction Systems><Signaling><Specificity><Structure of germinal center of lymph node><TNFRSF5><TNFRSF5 gene><Transcription Factor NF-kB><Transcriptional Control><Transcriptional Regulation><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><United States National Institutes of Health><Vaccination><Vaccination acquired immunity><Vaccination induced immunity><Vaccine Adjuvant><Vaccines><Viral Burden><Viral Load><Viral Load result><Viral Pathogenesis><Work><antibody-based immunity><antigen antibody affinity><biological signal transduction><cellular differentiation><design><designing><developmental><dimer><disability><drug intervention><drug treatment><extracellular><floxed><floxed allele><flu infection><flu vaccine><flu virus infection><flu virus vaccine><gene regulatory network><human disease><immune modulators><immunogen><immunomodulatory molecules><immunoregulator><immunoregulatory molecules><improved><infected with flu><infected with flu virus><infected with influenza><infected with influenza virus><influenza infection><influenza virus infection><influenza virus vaccine><influenzavirus><inhibitor><innovate><innovation><innovative><insight><kappa B Enhancer Binding Protein><mouse model><murine model><neutralizing antibody><novel><nuclear factor kappa beta><p50><pathogen><pharmaceutical intervention><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><plasma cell differentiation><plasmocyte><preference><programs><response><social role><somatic hypermutation><success><tool><vaccine acquired immunity><vaccine against flu><vaccine against influenza><vaccine associated immunity><vaccine response><vaccine responsiveness><vaccine-induced immunity><vaccine-induced protection><vaccine-induced response><virus pathogenesis>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Marisa McGinley

CLEVELAND CLINIC LERNER COM-CWRU, CLEVELAND, OH

Good lead · 54/100
Likely hiring
Above-average budget
Active award
$617,044
FY 2025

Project Title

Clinical and Economic Impact of Teleneurology vs Standard in Clinic Care for Multiple Sclerosis: A Randomized Trial

Grant Number:

5R01NR020323-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/26/2022

End Date:

6/30/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ ABSTRACT Multiple sclerosis (MS) patients have higher healthcare utilization, reduced work productivity, reduced quality- adjusted life years, and lower health-related quality of life (QOL) relative to the general population. The current standard of outpatient MS care depends on in-...

Research Terms

<2-arm study><21+ years old><Absenteeism at work><Academy><Access to Care><Active Follow-up><Address><Adherence><Adult><Adult Human><Affect><American><Automobile Driving><Burden on their caregivers><COVID crisis><COVID epidemic><COVID pandemic><COVID-19 crisis><COVID-19 epidemic><COVID-19 era><COVID-19 global health crisis><COVID-19 global pandemic><COVID-19 health crisis><COVID-19 pandemic><COVID-19 period><COVID-19 public health crisis><COVID-19 years><Caregiver Burden><Caring><Chronic><Clinic><Clinic Visits><Clinical><Communities><Comprehensive Health Care><Cost Effectiveness Analysis><Data><Diagnosis><Digital biomarker><Direct Costs><Disease><Disorder><Disseminated Sclerosis><Dropout><Drugs><ED visit><ER visit><Emergency care visit><Emergency department visit><Emergency hospital visit><Emergency room visit><Employee Absenteeism><Enrollment><Ensure><Evaluation><Face><Facilities and Administrative Costs><General Population><General Public><Goals><Health Care><Health Care Costs><Health Care Utilization><Health Costs><Health Services Accessibility><Home><Hospital Admission><Hospitalization><Immune><Immunes><Improve Access><Indirect Costs><Intervention><Interview><Knowledge><MS patient><Mediating><Medical><Medication><Methodology><Methods><Modality><Modeling><Multiple Sclerosis><Neurologist><Neurology><Newly Diagnosed><Out-patients><Outcome><Outpatients><P50 Mechanism><P50 Program><Participant><Patient Outcomes Assessments><Patient Reported Measures><Patient Reported Outcomes><Patients><Patterns of Care><Perception><Persons><Pharmaceutical Preparations><Policies><Population><Position><Positioning Attribute><Procedures><Productivity><Provider><QALY><QOL><Quality of life><Quality-Adjusted Life Expectancy><Quality-Adjusted Life Years><Randomization trial><Randomized><Recommendation><Regulation><Research><Research Resources><Resources><SARS-CoV-2 epidemic><SARS-CoV-2 global health crisis><SARS-CoV-2 global pandemic><SARS-CoV-2 pandemic><SARS-coronavirus-2 epidemic><SARS-coronavirus-2 pandemic><Sampling><Savings><Schedule><Secure><Services><Severe Acute Respiratory Syndrome CoV 2 epidemic><Severe Acute Respiratory Syndrome CoV 2 pandemic><Severe acute respiratory syndrome coronavirus 2 epidemic><Severe acute respiratory syndrome coronavirus 2 pandemic><Site><Specialized Center><Standardization><Survey Instrument><Surveys><System><Testing><Time><Travel><Visit><Work><access to health services><access to services><access to treatment><accessibility to health services><active followup><adulthood><availability of services><burden in caregivers><burden of their caregivers><burden on caregivers><care access><care costs><care delivery><central nervous system demyelinating disease><central nervous system demyelinating disorder><clinical care><compare cost><comprehensive care><coronavirus disease 2019 crisis><coronavirus disease 2019 epidemic><coronavirus disease 2019 global health crisis><coronavirus disease 2019 global pandemic><coronavirus disease 2019 health crisis><coronavirus disease 2019 pandemic><coronavirus disease 2019 public health crisis><coronavirus disease crisis><coronavirus disease epidemic><coronavirus disease pandemic><coronavirus disease-19 global pandemic><coronavirus disease-19 pandemic><cost><cost comparison><cost efficient analysis><cost-effective analysis><design><designing><digital marker><disability><driving><drug/agent><economic impact><enroll><experience><faces><facial><follow up><follow-up><followed up><followup><health IT><health and care delivery><health care delivery><health care service use><health care service utilization><health delivery systems><health information technology><health related quality of life><health service access><health services availability><health services delivery><homes><hospitalization rates><improved><insight><insular sclerosis><missing work><multidisciplinary><multiple sclerosis patient><novel><patients with MS><patients with multiple sclerosis><people with Multiple sclerosis><pilot trial><preference><randomisation><randomization><randomized trial><randomized, clinical trials><randomly assigned><satisfaction><service availability><severe acute respiratory syndrome coronavirus 2 global health crisis><severe acute respiratory syndrome coronavirus 2 global pandemic><telehealth><telehealth care><telehealthcare><teleneurology><theories><treatment access><two-arm study><usability>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Suvarna Alladi

EMORY UNIVERSITY, ATLANTA, GA

Good lead · 54/100
Likely hiring
Above-average budget
Active award
$595,065
FY 2025

Project Title

P-CARRS-BRAIN: Multi-domain (genetic, socio-behavioral, vascular) risk factors and prediction of Alzheimer’s Disease continuum in South Asians in India

Grant Number:

3R01AG089759-02S1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2024

End Date:

8/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT While it is widely acknowledged that Alzheimer’s disease and related dementias (AD/ADRD) have an extended preclinical phase, there are sparse data on the cognitive and pathobiological changes in middle-ages, a critical window for preventative intervention in people likely to...

Research Terms

<21+ years old><AD dementia><AD pathology><AD related dementia><ADRD><AI Augmented><AI assisted><AI driven><AI enhanced><AI integrated><AI powered><Active Follow-up><Address><Adult><Adult Human><Age><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's biomarker><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease biological marker><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease pathology><Alzheimer's disease related dementia><Alzheimer's pathology><Alzheimers Dementia><Alzheimer’s biological marker><Alzheimer’s disease biomarker><Amentia><Apoplexy><Arteriosclerotic Dementia><Artificial Intelligence enhanced><Asian group><Asian individual><Asian people><Asian population><Asians><Assessment instrument><Assessment tool><Astroprotein><Augmented by AI><Augmented by the AI><Augmented with AI><Augmented with the AI><Behavioral><Biological><Biological Markers><Blood Plasma><Blood Vessels><Brain><Brain Nervous System><Brain Vascular Accident><Causality><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Classification><Clinical><Cognition><Cognitive><Collection><Complex><Data><Data Management and Analysis Core><Data Management and Statistical Analysis Core><Data Management and Statistical Core><Dementia><Detection><Diabetes Mellitus><Diagnosis><Digital biomarker><Disease><Disorder><Dyslipidemias><Early Diagnosis><Encephalon><Enrollment><Epidemic><Epidemiology><Etiology><European><Exhibits><Female><Funding><GFA-Protein><GFAP><GWA study><GWAS><Genetic><Genetic Risk><Genomics><Genotype><Glial Fibrillary Acid Protein><Glial Fibrillary Acidic Protein><Glial Intermediate Filament Protein><Goals><Hypertension><Image><India><Individual><Infrastructure><Knowledge><Language><Lead><Life><Life Cycle><Life Cycle Stages><Life Style><Lifestyle><Linguistic><Linguistics><Link><Longitudinal Studies><MR Imaging><MR Tomography><MRI><MRIs><Machine Learning><Magnetic Resonance Imaging><Measurement><Measures><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Metabolic><Myocardium><NHLBI><NMR Imaging><NMR Tomography><National Heart, Lung, and Blood Institute><Natural History><Neuropsychologies><Neuropsychology><Nuclear Magnetic Resonance Imaging><Organ><Outcome><Participant><Pathway interactions><Pattern><Pb element><Persons><Phase><Phenotype><Plasma><Plasma Serum><Population><Predicting Risk><Predisposition><Preventative intervention><Prevention><Primary Senile Degenerative Dementia><Protocol><Protocols documentation><Research><Reticuloendothelial System, Serum, Plasma><Retina><Risk><Risk Factors><Sampling><Sleep><Social Behavior><South Asian><Span 20><Spectroscopy><Spectrum Analyses><Spectrum Analysis><Standardization><Statistical Methods><Stress><Stroke><Susceptibility><System><Systematics><Therapeutic><Vascular Cognitive Impairment><Vascular Dementia><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Zeugmatography><accelerated aging><accelerated biological age><accelerated biological aging><active followup><adulthood><age acceleration><aged><aged group><aged groups><aged individual><aged individuals><aged people><aged person><aged persons><aged population><aged populations><ages><aging population><artificial intelligence assisted><artificial intelligence augmented><artificial intelligence driven><artificial intelligence integrated><artificial intelligence powered><bio-markers><biobank><biologic><biologic marker><biomarker><biorepository><brain MR imaging><brain MRI><brain attack><brain magnetic resonance imaging><cardiac muscle><cardiometabolic><cardiometabolism><causation><cerebral MR imaging><cerebral MRI><cerebral magnetic resonance imaging><cerebral vascular accident><cerebrovascular accident><cerebrovascular contribution to cognitive impairment><cerebrovascular contributions to cognitive dysfunction><cerebrovascular contributions to dementia><cognitive change><cohort><computer based prediction><dementia risk><diabetes><digital><digital cognitive assessment><digital cognitive test><digital marker><disease causation><early detection><early onset><enhanced with AI><enhanced with Artificial Intelligence><enroll><entire genome><epidemiologic><epidemiological><experience><family structure><follow up><follow-up><followed up><followup><forecasting risk><full genome><gene locus><genetic locus><genome sequencing><genome wide association><genome wide association scan><genome wide association study><genomewide association scan><genomewide association study><genomic location><genomic locus><heart muscle><heavy metal Pb><heavy metal lead><high blood pressure><high dimensional data><high risk><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><imaging><intervention for prevention><late in life><late life><learning network><life course><literate><long-term study><longitudinal design><longitudinal experimental design><longitudinal outcome studies><longitudinal research design><longitudinal study design><machine based learning><machine learning based prediction model><machine learning based predictive model><machine learning prediction><machine learning prediction model><malleable risk><mid life><mid-life><middle age><middle aged><midlife><mild cognitive disorder><mild cognitive impairment><modifiable risk><multi-modal data><multi-modal datasets><multi-modality><multidimensional data><multidimensional datasets><multimodal data><multimodal datasets><multimodality><neural imaging><neuro-imaging><neuroimaging><neuroimaging biomarker><neuroimaging marker><neurological imaging><neuropsychologic><new marker><novel><novel biomarker><novel marker><pathway><phenotypic data><pollutant><population aging><population based><pre-clinical><preclinical><predict risk><predict risks><predicted risk><predicted risks><predicting risks><predictive modeling><predictive risk><predictive tools><predicts risk><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><primary degenerative dementia><retinal imaging><risk factor for dementia><risk for dementia><risk prediction><risk predictions><senile dementia of the Alzheimer type><social culture><social structural><social structure><socio-cultural><socio-demographics><socio-structural><sociobehavior><sociobehavioral><sociocultural><sociodemographics><sociostructural><statistic methods><stroked><strokes><vascular><vascular and cognitive impairment><vascular cognition impairment><vascular cognitive decline><vascular cognitive disease><vascular cognitive disorder><vascular cognitive dysfunction><vascular contributions in dementia><vascular contributions to cognitive decline><vascular contributions to cognitive impairment><vascular contributions to dementia><vascular disease and impaired cognition><vascular dysfunction resulting in cognitive decline><vascular related cognitive decline><vascular related cognitive impairment><vascular related dementia><whole genome><whole genome association analysis><whole genome association study><younger age><♀>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

ALLAN I LEVEY

EMORY UNIVERSITY, ATLANTA, GA

Good lead · 54/100
Likely hiring
Above-average budget
Active award
$595,065
FY 2025

Project Title

P-CARRS-BRAIN: Multi-domain (genetic, socio-behavioral, vascular) risk factors and prediction of Alzheimer’s Disease continuum in South Asians in India

Grant Number:

3R01AG089759-02S1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2024

End Date:

8/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT While it is widely acknowledged that Alzheimer’s disease and related dementias (AD/ADRD) have an extended preclinical phase, there are sparse data on the cognitive and pathobiological changes in middle-ages, a critical window for preventative intervention in people likely to...

Research Terms

<21+ years old><AD dementia><AD pathology><AD related dementia><ADRD><AI Augmented><AI assisted><AI driven><AI enhanced><AI integrated><AI powered><Active Follow-up><Address><Adult><Adult Human><Age><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's biomarker><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease biological marker><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease pathology><Alzheimer's disease related dementia><Alzheimer's pathology><Alzheimers Dementia><Alzheimer’s biological marker><Alzheimer’s disease biomarker><Amentia><Apoplexy><Arteriosclerotic Dementia><Artificial Intelligence enhanced><Asian group><Asian individual><Asian people><Asian population><Asians><Assessment instrument><Assessment tool><Astroprotein><Augmented by AI><Augmented by the AI><Augmented with AI><Augmented with the AI><Behavioral><Biological><Biological Markers><Blood Plasma><Blood Vessels><Brain><Brain Nervous System><Brain Vascular Accident><Causality><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Classification><Clinical><Cognition><Cognitive><Collection><Complex><Data><Data Management and Analysis Core><Data Management and Statistical Analysis Core><Data Management and Statistical Core><Dementia><Detection><Diabetes Mellitus><Diagnosis><Digital biomarker><Disease><Disorder><Dyslipidemias><Early Diagnosis><Encephalon><Enrollment><Epidemic><Epidemiology><Etiology><European><Exhibits><Female><Funding><GFA-Protein><GFAP><GWA study><GWAS><Genetic><Genetic Risk><Genomics><Genotype><Glial Fibrillary Acid Protein><Glial Fibrillary Acidic Protein><Glial Intermediate Filament Protein><Goals><Hypertension><Image><India><Individual><Infrastructure><Knowledge><Language><Lead><Life><Life Cycle><Life Cycle Stages><Life Style><Lifestyle><Linguistic><Linguistics><Link><Longitudinal Studies><MR Imaging><MR Tomography><MRI><MRIs><Machine Learning><Magnetic Resonance Imaging><Measurement><Measures><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Metabolic><Myocardium><NHLBI><NMR Imaging><NMR Tomography><National Heart, Lung, and Blood Institute><Natural History><Neuropsychologies><Neuropsychology><Nuclear Magnetic Resonance Imaging><Organ><Outcome><Participant><Pathway interactions><Pattern><Pb element><Persons><Phase><Phenotype><Plasma><Plasma Serum><Population><Predicting Risk><Predisposition><Preventative intervention><Prevention><Primary Senile Degenerative Dementia><Protocol><Protocols documentation><Research><Reticuloendothelial System, Serum, Plasma><Retina><Risk><Risk Factors><Sampling><Sleep><Social Behavior><South Asian><Span 20><Spectroscopy><Spectrum Analyses><Spectrum Analysis><Standardization><Statistical Methods><Stress><Stroke><Susceptibility><System><Systematics><Therapeutic><Vascular Cognitive Impairment><Vascular Dementia><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Zeugmatography><accelerated aging><accelerated biological age><accelerated biological aging><active followup><adulthood><age acceleration><aged><aged group><aged groups><aged individual><aged individuals><aged people><aged person><aged persons><aged population><aged populations><ages><aging population><artificial intelligence assisted><artificial intelligence augmented><artificial intelligence driven><artificial intelligence integrated><artificial intelligence powered><bio-markers><biobank><biologic><biologic marker><biomarker><biorepository><brain MR imaging><brain MRI><brain attack><brain magnetic resonance imaging><cardiac muscle><cardiometabolic><cardiometabolism><causation><cerebral MR imaging><cerebral MRI><cerebral magnetic resonance imaging><cerebral vascular accident><cerebrovascular accident><cerebrovascular contribution to cognitive impairment><cerebrovascular contributions to cognitive dysfunction><cerebrovascular contributions to dementia><cognitive change><cohort><computer based prediction><dementia risk><diabetes><digital><digital cognitive assessment><digital cognitive test><digital marker><disease causation><early detection><early onset><enhanced with AI><enhanced with Artificial Intelligence><enroll><entire genome><epidemiologic><epidemiological><experience><family structure><follow up><follow-up><followed up><followup><forecasting risk><full genome><gene locus><genetic locus><genome sequencing><genome wide association><genome wide association scan><genome wide association study><genomewide association scan><genomewide association study><genomic location><genomic locus><heart muscle><heavy metal Pb><heavy metal lead><high blood pressure><high dimensional data><high risk><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><imaging><intervention for prevention><late in life><late life><learning network><life course><literate><long-term study><longitudinal design><longitudinal experimental design><longitudinal outcome studies><longitudinal research design><longitudinal study design><machine based learning><machine learning based prediction model><machine learning based predictive model><machine learning prediction><machine learning prediction model><malleable risk><mid life><mid-life><middle age><middle aged><midlife><mild cognitive disorder><mild cognitive impairment><modifiable risk><multi-modal data><multi-modal datasets><multi-modality><multidimensional data><multidimensional datasets><multimodal data><multimodal datasets><multimodality><neural imaging><neuro-imaging><neuroimaging><neuroimaging biomarker><neuroimaging marker><neurological imaging><neuropsychologic><new marker><novel><novel biomarker><novel marker><pathway><phenotypic data><pollutant><population aging><population based><pre-clinical><preclinical><predict risk><predict risks><predicted risk><predicted risks><predicting risks><predictive modeling><predictive risk><predictive tools><predicts risk><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><primary degenerative dementia><retinal imaging><risk factor for dementia><risk for dementia><risk prediction><risk predictions><senile dementia of the Alzheimer type><social culture><social structural><social structure><socio-cultural><socio-demographics><socio-structural><sociobehavior><sociobehavioral><sociocultural><sociodemographics><sociostructural><statistic methods><stroked><strokes><vascular><vascular and cognitive impairment><vascular cognition impairment><vascular cognitive decline><vascular cognitive disease><vascular cognitive disorder><vascular cognitive dysfunction><vascular contributions in dementia><vascular contributions to cognitive decline><vascular contributions to cognitive impairment><vascular contributions to dementia><vascular disease and impaired cognition><vascular dysfunction resulting in cognitive decline><vascular related cognitive decline><vascular related cognitive impairment><vascular related dementia><whole genome><whole genome association analysis><whole genome association study><younger age><♀>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Viswanathan Mohan

EMORY UNIVERSITY, ATLANTA, GA

Good lead · 54/100
Likely hiring
Above-average budget
Active award
$595,065
FY 2025

Project Title

P-CARRS-BRAIN: Multi-domain (genetic, socio-behavioral, vascular) risk factors and prediction of Alzheimer’s Disease continuum in South Asians in India

Grant Number:

3R01AG089759-02S1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2024

End Date:

8/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT While it is widely acknowledged that Alzheimer’s disease and related dementias (AD/ADRD) have an extended preclinical phase, there are sparse data on the cognitive and pathobiological changes in middle-ages, a critical window for preventative intervention in people likely to...

Research Terms

<21+ years old><AD dementia><AD pathology><AD related dementia><ADRD><AI Augmented><AI assisted><AI driven><AI enhanced><AI integrated><AI powered><Active Follow-up><Address><Adult><Adult Human><Age><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's biomarker><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease biological marker><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease pathology><Alzheimer's disease related dementia><Alzheimer's pathology><Alzheimers Dementia><Alzheimer’s biological marker><Alzheimer’s disease biomarker><Amentia><Apoplexy><Arteriosclerotic Dementia><Artificial Intelligence enhanced><Asian group><Asian individual><Asian people><Asian population><Asians><Assessment instrument><Assessment tool><Astroprotein><Augmented by AI><Augmented by the AI><Augmented with AI><Augmented with the AI><Behavioral><Biological><Biological Markers><Blood Plasma><Blood Vessels><Brain><Brain Nervous System><Brain Vascular Accident><Causality><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Classification><Clinical><Cognition><Cognitive><Collection><Complex><Data><Data Management and Analysis Core><Data Management and Statistical Analysis Core><Data Management and Statistical Core><Dementia><Detection><Diabetes Mellitus><Diagnosis><Digital biomarker><Disease><Disorder><Dyslipidemias><Early Diagnosis><Encephalon><Enrollment><Epidemic><Epidemiology><Etiology><European><Exhibits><Female><Funding><GFA-Protein><GFAP><GWA study><GWAS><Genetic><Genetic Risk><Genomics><Genotype><Glial Fibrillary Acid Protein><Glial Fibrillary Acidic Protein><Glial Intermediate Filament Protein><Goals><Hypertension><Image><India><Individual><Infrastructure><Knowledge><Language><Lead><Life><Life Cycle><Life Cycle Stages><Life Style><Lifestyle><Linguistic><Linguistics><Link><Longitudinal Studies><MR Imaging><MR Tomography><MRI><MRIs><Machine Learning><Magnetic Resonance Imaging><Measurement><Measures><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Metabolic><Myocardium><NHLBI><NMR Imaging><NMR Tomography><National Heart, Lung, and Blood Institute><Natural History><Neuropsychologies><Neuropsychology><Nuclear Magnetic Resonance Imaging><Organ><Outcome><Participant><Pathway interactions><Pattern><Pb element><Persons><Phase><Phenotype><Plasma><Plasma Serum><Population><Predicting Risk><Predisposition><Preventative intervention><Prevention><Primary Senile Degenerative Dementia><Protocol><Protocols documentation><Research><Reticuloendothelial System, Serum, Plasma><Retina><Risk><Risk Factors><Sampling><Sleep><Social Behavior><South Asian><Span 20><Spectroscopy><Spectrum Analyses><Spectrum Analysis><Standardization><Statistical Methods><Stress><Stroke><Susceptibility><System><Systematics><Therapeutic><Vascular Cognitive Impairment><Vascular Dementia><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Zeugmatography><accelerated aging><accelerated biological age><accelerated biological aging><active followup><adulthood><age acceleration><aged><aged group><aged groups><aged individual><aged individuals><aged people><aged person><aged persons><aged population><aged populations><ages><aging population><artificial intelligence assisted><artificial intelligence augmented><artificial intelligence driven><artificial intelligence integrated><artificial intelligence powered><bio-markers><biobank><biologic><biologic marker><biomarker><biorepository><brain MR imaging><brain MRI><brain attack><brain magnetic resonance imaging><cardiac muscle><cardiometabolic><cardiometabolism><causation><cerebral MR imaging><cerebral MRI><cerebral magnetic resonance imaging><cerebral vascular accident><cerebrovascular accident><cerebrovascular contribution to cognitive impairment><cerebrovascular contributions to cognitive dysfunction><cerebrovascular contributions to dementia><cognitive change><cohort><computer based prediction><dementia risk><diabetes><digital><digital cognitive assessment><digital cognitive test><digital marker><disease causation><early detection><early onset><enhanced with AI><enhanced with Artificial Intelligence><enroll><entire genome><epidemiologic><epidemiological><experience><family structure><follow up><follow-up><followed up><followup><forecasting risk><full genome><gene locus><genetic locus><genome sequencing><genome wide association><genome wide association scan><genome wide association study><genomewide association scan><genomewide association study><genomic location><genomic locus><heart muscle><heavy metal Pb><heavy metal lead><high blood pressure><high dimensional data><high risk><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><imaging><intervention for prevention><late in life><late life><learning network><life course><literate><long-term study><longitudinal design><longitudinal experimental design><longitudinal outcome studies><longitudinal research design><longitudinal study design><machine based learning><machine learning based prediction model><machine learning based predictive model><machine learning prediction><machine learning prediction model><malleable risk><mid life><mid-life><middle age><middle aged><midlife><mild cognitive disorder><mild cognitive impairment><modifiable risk><multi-modal data><multi-modal datasets><multi-modality><multidimensional data><multidimensional datasets><multimodal data><multimodal datasets><multimodality><neural imaging><neuro-imaging><neuroimaging><neuroimaging biomarker><neuroimaging marker><neurological imaging><neuropsychologic><new marker><novel><novel biomarker><novel marker><pathway><phenotypic data><pollutant><population aging><population based><pre-clinical><preclinical><predict risk><predict risks><predicted risk><predicted risks><predicting risks><predictive modeling><predictive risk><predictive tools><predicts risk><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><primary degenerative dementia><retinal imaging><risk factor for dementia><risk for dementia><risk prediction><risk predictions><senile dementia of the Alzheimer type><social culture><social structural><social structure><socio-cultural><socio-demographics><socio-structural><sociobehavior><sociobehavioral><sociocultural><sociodemographics><sociostructural><statistic methods><stroked><strokes><vascular><vascular and cognitive impairment><vascular cognition impairment><vascular cognitive decline><vascular cognitive disease><vascular cognitive disorder><vascular cognitive dysfunction><vascular contributions in dementia><vascular contributions to cognitive decline><vascular contributions to cognitive impairment><vascular contributions to dementia><vascular disease and impaired cognition><vascular dysfunction resulting in cognitive decline><vascular related cognitive decline><vascular related cognitive impairment><vascular related dementia><whole genome><whole genome association analysis><whole genome association study><younger age><♀>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Kabayam M Venkat Narayan

EMORY UNIVERSITY, ATLANTA, GA

Good lead · 54/100
Likely hiring
Above-average budget
Active award
$595,065
FY 2025

Project Title

P-CARRS-BRAIN: Multi-domain (genetic, socio-behavioral, vascular) risk factors and prediction of Alzheimer’s Disease continuum in South Asians in India

Grant Number:

3R01AG089759-02S1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2024

End Date:

8/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT While it is widely acknowledged that Alzheimer’s disease and related dementias (AD/ADRD) have an extended preclinical phase, there are sparse data on the cognitive and pathobiological changes in middle-ages, a critical window for preventative intervention in people likely to...

Research Terms

<21+ years old><AD dementia><AD pathology><AD related dementia><ADRD><AI Augmented><AI assisted><AI driven><AI enhanced><AI integrated><AI powered><Active Follow-up><Address><Adult><Adult Human><Age><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's biomarker><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease biological marker><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease pathology><Alzheimer's disease related dementia><Alzheimer's pathology><Alzheimers Dementia><Alzheimer’s biological marker><Alzheimer’s disease biomarker><Amentia><Apoplexy><Arteriosclerotic Dementia><Artificial Intelligence enhanced><Asian group><Asian individual><Asian people><Asian population><Asians><Assessment instrument><Assessment tool><Astroprotein><Augmented by AI><Augmented by the AI><Augmented with AI><Augmented with the AI><Behavioral><Biological><Biological Markers><Blood Plasma><Blood Vessels><Brain><Brain Nervous System><Brain Vascular Accident><Causality><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Classification><Clinical><Cognition><Cognitive><Collection><Complex><Data><Data Management and Analysis Core><Data Management and Statistical Analysis Core><Data Management and Statistical Core><Dementia><Detection><Diabetes Mellitus><Diagnosis><Digital biomarker><Disease><Disorder><Dyslipidemias><Early Diagnosis><Encephalon><Enrollment><Epidemic><Epidemiology><Etiology><European><Exhibits><Female><Funding><GFA-Protein><GFAP><GWA study><GWAS><Genetic><Genetic Risk><Genomics><Genotype><Glial Fibrillary Acid Protein><Glial Fibrillary Acidic Protein><Glial Intermediate Filament Protein><Goals><Hypertension><Image><India><Individual><Infrastructure><Knowledge><Language><Lead><Life><Life Cycle><Life Cycle Stages><Life Style><Lifestyle><Linguistic><Linguistics><Link><Longitudinal Studies><MR Imaging><MR Tomography><MRI><MRIs><Machine Learning><Magnetic Resonance Imaging><Measurement><Measures><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Metabolic><Myocardium><NHLBI><NMR Imaging><NMR Tomography><National Heart, Lung, and Blood Institute><Natural History><Neuropsychologies><Neuropsychology><Nuclear Magnetic Resonance Imaging><Organ><Outcome><Participant><Pathway interactions><Pattern><Pb element><Persons><Phase><Phenotype><Plasma><Plasma Serum><Population><Predicting Risk><Predisposition><Preventative intervention><Prevention><Primary Senile Degenerative Dementia><Protocol><Protocols documentation><Research><Reticuloendothelial System, Serum, Plasma><Retina><Risk><Risk Factors><Sampling><Sleep><Social Behavior><South Asian><Span 20><Spectroscopy><Spectrum Analyses><Spectrum Analysis><Standardization><Statistical Methods><Stress><Stroke><Susceptibility><System><Systematics><Therapeutic><Vascular Cognitive Impairment><Vascular Dementia><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Zeugmatography><accelerated aging><accelerated biological age><accelerated biological aging><active followup><adulthood><age acceleration><aged><aged group><aged groups><aged individual><aged individuals><aged people><aged person><aged persons><aged population><aged populations><ages><aging population><artificial intelligence assisted><artificial intelligence augmented><artificial intelligence driven><artificial intelligence integrated><artificial intelligence powered><bio-markers><biobank><biologic><biologic marker><biomarker><biorepository><brain MR imaging><brain MRI><brain attack><brain magnetic resonance imaging><cardiac muscle><cardiometabolic><cardiometabolism><causation><cerebral MR imaging><cerebral MRI><cerebral magnetic resonance imaging><cerebral vascular accident><cerebrovascular accident><cerebrovascular contribution to cognitive impairment><cerebrovascular contributions to cognitive dysfunction><cerebrovascular contributions to dementia><cognitive change><cohort><computer based prediction><dementia risk><diabetes><digital><digital cognitive assessment><digital cognitive test><digital marker><disease causation><early detection><early onset><enhanced with AI><enhanced with Artificial Intelligence><enroll><entire genome><epidemiologic><epidemiological><experience><family structure><follow up><follow-up><followed up><followup><forecasting risk><full genome><gene locus><genetic locus><genome sequencing><genome wide association><genome wide association scan><genome wide association study><genomewide association scan><genomewide association study><genomic location><genomic locus><heart muscle><heavy metal Pb><heavy metal lead><high blood pressure><high dimensional data><high risk><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><imaging><intervention for prevention><late in life><late life><learning network><life course><literate><long-term study><longitudinal design><longitudinal experimental design><longitudinal outcome studies><longitudinal research design><longitudinal study design><machine based learning><machine learning based prediction model><machine learning based predictive model><machine learning prediction><machine learning prediction model><malleable risk><mid life><mid-life><middle age><middle aged><midlife><mild cognitive disorder><mild cognitive impairment><modifiable risk><multi-modal data><multi-modal datasets><multi-modality><multidimensional data><multidimensional datasets><multimodal data><multimodal datasets><multimodality><neural imaging><neuro-imaging><neuroimaging><neuroimaging biomarker><neuroimaging marker><neurological imaging><neuropsychologic><new marker><novel><novel biomarker><novel marker><pathway><phenotypic data><pollutant><population aging><population based><pre-clinical><preclinical><predict risk><predict risks><predicted risk><predicted risks><predicting risks><predictive modeling><predictive risk><predictive tools><predicts risk><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><primary degenerative dementia><retinal imaging><risk factor for dementia><risk for dementia><risk prediction><risk predictions><senile dementia of the Alzheimer type><social culture><social structural><social structure><socio-cultural><socio-demographics><socio-structural><sociobehavior><sociobehavioral><sociocultural><sociodemographics><sociostructural><statistic methods><stroked><strokes><vascular><vascular and cognitive impairment><vascular cognition impairment><vascular cognitive decline><vascular cognitive disease><vascular cognitive disorder><vascular cognitive dysfunction><vascular contributions in dementia><vascular contributions to cognitive decline><vascular contributions to cognitive impairment><vascular contributions to dementia><vascular disease and impaired cognition><vascular dysfunction resulting in cognitive decline><vascular related cognitive decline><vascular related cognitive impairment><vascular related dementia><whole genome><whole genome association analysis><whole genome association study><younger age><♀>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Dorairaj Prabhakaran

EMORY UNIVERSITY, ATLANTA, GA

Good lead · 54/100
Likely hiring
Above-average budget
Active award
$595,065
FY 2025

Project Title

P-CARRS-BRAIN: Multi-domain (genetic, socio-behavioral, vascular) risk factors and prediction of Alzheimer’s Disease continuum in South Asians in India

Grant Number:

3R01AG089759-02S1

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2024

End Date:

8/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT While it is widely acknowledged that Alzheimer’s disease and related dementias (AD/ADRD) have an extended preclinical phase, there are sparse data on the cognitive and pathobiological changes in middle-ages, a critical window for preventative intervention in people likely to...

Research Terms

<21+ years old><AD dementia><AD pathology><AD related dementia><ADRD><AI Augmented><AI assisted><AI driven><AI enhanced><AI integrated><AI powered><Active Follow-up><Address><Adult><Adult Human><Age><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's biomarker><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease biological marker><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease pathology><Alzheimer's disease related dementia><Alzheimer's pathology><Alzheimers Dementia><Alzheimer’s biological marker><Alzheimer’s disease biomarker><Amentia><Apoplexy><Arteriosclerotic Dementia><Artificial Intelligence enhanced><Asian group><Asian individual><Asian people><Asian population><Asians><Assessment instrument><Assessment tool><Astroprotein><Augmented by AI><Augmented by the AI><Augmented with AI><Augmented with the AI><Behavioral><Biological><Biological Markers><Blood Plasma><Blood Vessels><Brain><Brain Nervous System><Brain Vascular Accident><Causality><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Classification><Clinical><Cognition><Cognitive><Collection><Complex><Data><Data Management and Analysis Core><Data Management and Statistical Analysis Core><Data Management and Statistical Core><Dementia><Detection><Diabetes Mellitus><Diagnosis><Digital biomarker><Disease><Disorder><Dyslipidemias><Early Diagnosis><Encephalon><Enrollment><Epidemic><Epidemiology><Etiology><European><Exhibits><Female><Funding><GFA-Protein><GFAP><GWA study><GWAS><Genetic><Genetic Risk><Genomics><Genotype><Glial Fibrillary Acid Protein><Glial Fibrillary Acidic Protein><Glial Intermediate Filament Protein><Goals><Hypertension><Image><India><Individual><Infrastructure><Knowledge><Language><Lead><Life><Life Cycle><Life Cycle Stages><Life Style><Lifestyle><Linguistic><Linguistics><Link><Longitudinal Studies><MR Imaging><MR Tomography><MRI><MRIs><Machine Learning><Magnetic Resonance Imaging><Measurement><Measures><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Metabolic><Myocardium><NHLBI><NMR Imaging><NMR Tomography><National Heart, Lung, and Blood Institute><Natural History><Neuropsychologies><Neuropsychology><Nuclear Magnetic Resonance Imaging><Organ><Outcome><Participant><Pathway interactions><Pattern><Pb element><Persons><Phase><Phenotype><Plasma><Plasma Serum><Population><Predicting Risk><Predisposition><Preventative intervention><Prevention><Primary Senile Degenerative Dementia><Protocol><Protocols documentation><Research><Reticuloendothelial System, Serum, Plasma><Retina><Risk><Risk Factors><Sampling><Sleep><Social Behavior><South Asian><Span 20><Spectroscopy><Spectrum Analyses><Spectrum Analysis><Standardization><Statistical Methods><Stress><Stroke><Susceptibility><System><Systematics><Therapeutic><Vascular Cognitive Impairment><Vascular Dementia><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Zeugmatography><accelerated aging><accelerated biological age><accelerated biological aging><active followup><adulthood><age acceleration><aged><aged group><aged groups><aged individual><aged individuals><aged people><aged person><aged persons><aged population><aged populations><ages><aging population><artificial intelligence assisted><artificial intelligence augmented><artificial intelligence driven><artificial intelligence integrated><artificial intelligence powered><bio-markers><biobank><biologic><biologic marker><biomarker><biorepository><brain MR imaging><brain MRI><brain attack><brain magnetic resonance imaging><cardiac muscle><cardiometabolic><cardiometabolism><causation><cerebral MR imaging><cerebral MRI><cerebral magnetic resonance imaging><cerebral vascular accident><cerebrovascular accident><cerebrovascular contribution to cognitive impairment><cerebrovascular contributions to cognitive dysfunction><cerebrovascular contributions to dementia><cognitive change><cohort><computer based prediction><dementia risk><diabetes><digital><digital cognitive assessment><digital cognitive test><digital marker><disease causation><early detection><early onset><enhanced with AI><enhanced with Artificial Intelligence><enroll><entire genome><epidemiologic><epidemiological><experience><family structure><follow up><follow-up><followed up><followup><forecasting risk><full genome><gene locus><genetic locus><genome sequencing><genome wide association><genome wide association scan><genome wide association study><genomewide association scan><genomewide association study><genomic location><genomic locus><heart muscle><heavy metal Pb><heavy metal lead><high blood pressure><high dimensional data><high risk><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><imaging><intervention for prevention><late in life><late life><learning network><life course><literate><long-term study><longitudinal design><longitudinal experimental design><longitudinal outcome studies><longitudinal research design><longitudinal study design><machine based learning><machine learning based prediction model><machine learning based predictive model><machine learning prediction><machine learning prediction model><malleable risk><mid life><mid-life><middle age><middle aged><midlife><mild cognitive disorder><mild cognitive impairment><modifiable risk><multi-modal data><multi-modal datasets><multi-modality><multidimensional data><multidimensional datasets><multimodal data><multimodal datasets><multimodality><neural imaging><neuro-imaging><neuroimaging><neuroimaging biomarker><neuroimaging marker><neurological imaging><neuropsychologic><new marker><novel><novel biomarker><novel marker><pathway><phenotypic data><pollutant><population aging><population based><pre-clinical><preclinical><predict risk><predict risks><predicted risk><predicted risks><predicting risks><predictive modeling><predictive risk><predictive tools><predicts risk><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><primary degenerative dementia><retinal imaging><risk factor for dementia><risk for dementia><risk prediction><risk predictions><senile dementia of the Alzheimer type><social culture><social structural><social structure><socio-cultural><socio-demographics><socio-structural><sociobehavior><sociobehavioral><sociocultural><sociodemographics><sociostructural><statistic methods><stroked><strokes><vascular><vascular and cognitive impairment><vascular cognition impairment><vascular cognitive decline><vascular cognitive disease><vascular cognitive disorder><vascular cognitive dysfunction><vascular contributions in dementia><vascular contributions to cognitive decline><vascular contributions to cognitive impairment><vascular contributions to dementia><vascular disease and impaired cognition><vascular dysfunction resulting in cognitive decline><vascular related cognitive decline><vascular related cognitive impairment><vascular related dementia><whole genome><whole genome association analysis><whole genome association study><younger age><♀>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Allison G Hays

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

Good lead · 54/100
Likely hiring
Above-average budget
Active award
$555,864
FY 2025

Project Title

Stress, inflammation and coronary endothelial injury in preeclampsia

Grant Number:

5R01HL159715-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/2/2022

End Date:

6/30/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

Hypertensive disorders of pregnancy, such as preeclampsia (PEC) cause significant maternal morbidity and mortality, and have emerged as an important early life, and potentially modifiable, risk factor of heart disease in younger women. PEC is diagnosed as new onset hypertension after 20 weeks gestat...

Research Terms

<ASCVD><Adult-Onset Diabetes Mellitus><Affect><Angiotensin AT1 Receptor><Angiotensin II Type 1 Receptor><Angiotensins><Atherosclerosis><Atherosclerotic Cardiovascular Disease><Autoantibodies><Biological><Biological Markers><Biology><Blood Diseases><Blood Vessels><COBRE><Cardiac Diseases><Cardiac Disorders><Cardiac infarction><Cardiology><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Cells Placenta-Tissue><Center of Biomedical Research Excellence><Centers of Research Excellence><Cessation of life><Clinic><Clinical><Communication><Coronary><Coronary Arteriosclerosis><Coronary Artery Disease><Coronary Artery Disorder><Coronary Atherosclerosis><Coronary Vessel Anomalies><Coronary abnormalities><Coronary anomalies><Coronary artery dysfunction><Coronary dysfunction><Data><Death><Depressed mood><Development><Diagnosis><Discipline of obstetrics><Disease><Disease Outcome><Disorder><Dysfunction><EPH Gestosis><Endocrine Gland Secretion><Endocrinology><Endothelial Cells><Endothelium><Event><Functional disorder><Funding><Future><Gender><Gender Role><General Population><General Public><Gestation><Health><Heart Diseases><Heart Vascular><Hematologic Diseases><Hematological Disease><Hematological Disorder><High Risk Woman><History><Hormones><Human><Hypertension><Hypertension-Associated Pregnancy Disorder><Imaging Procedures><Imaging Technics><Imaging Techniques><Impairment><Inflammation><Injury><Intervention><Intervention Studies><Ischemia><Ketosis-Resistant Diabetes Mellitus><Knowledge><Life><Link><Lived experience><Lived experiences><MR Imaging><MR Tomography><MRI><MRIs><Magnetic Resonance Imaging><Maternal Mortality><Maturity-Onset Diabetes Mellitus><Measures><Medical><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Metabolism and Endocrinology><Methods><Modern Man><Myocardial Infarct><Myocardial Infarction><NIDDM><NIH><NMR Imaging><NMR Tomography><National Institutes of Health><Neighborhoods><Nodal><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Normal Placentoma><Nuclear Magnetic Resonance Imaging><Obesity><Obstetrics><Organ><Outcome><Oxidative Stress><P50 Mechanism><P50 Program><Pathogenesis><Patients><Physiologic><Physiological><Physiopathology><Placenta><Placenta Embryonic Tissue><Placentome><Play><Population><Post-partum Women><Postpartum Hypertension><Postpartum Period><Postpartum Women><Pre-Eclampsia><Preeclampsia><Pregnancy><Pregnancy Complications><Pregnancy Toxemias><Prognostic Marker><Prospective Studies><Proteinuria-Edema-Hypertension Gestosis><Psychologic Stress><Psychological Stress><Psychosocial Stress><Public Health><Receptor, Angiotensin, Type 1><Recording of previous events><Renin-Angiotensin System><Reporting><Reproducibility><Research Resources><Resources><Risk><Risk Factors><Role><Severities><Sex Roles><Slow-Onset Diabetes Mellitus><Social Behavior><Specialized Center><Stable Diabetes Mellitus><Stratification><Stress><T2 DM><T2D><T2DM><Techniques><Testing><Therapeutic Hormone><Time><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><United States National Institutes of Health><Vascular Diseases><Vascular Disorder><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Woman><Women's mortality><Work><Zeugmatography><adiposity><adult onset diabetes><age group><angiogenesis><angiotensin II type I receptor><at-risk females><at-risk women><atheromatosis><atherosclerotic coronary disease><atherosclerotic disease><atherosclerotic vascular disease><autoimmune antibody><autoreactive antibody><bio-markers><biologic><biologic marker><biomarker><blood disorder><blood pressure elevation><blood vessel disorder><cardiac disease risk><cardiac disorder risk><cardiac infarct><cardioprotectant><cardioprotection><cardioprotective><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><cardiovascular health><cardiovascular risk><cardiovascular risk factor><circulatory system><cohort><compare to control><comparison control><complications during pregnancy><coronary arterial disease><coronary artery abnormalities><coronary artery anomalies><coronary attack><coronary infarct><coronary infarction><corpulence><death among females><death among women><death in females><death in women><death rate among women><death rate in women><depressed><design><designing><developmental><elevated blood pressure><endothelial dysfunction><experience><female death><female mortality><females at high risk><heart attack><heart disease risk><heart disorder><heart disorder risk><heart infarct><heart infarction><high blood pressure><high risk females><high risk group><high risk individual><high risk people><high risk population><histories><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disease during pregnancy><hypertensive disease in pregnancy><hypertensive disease of pregnancy><hypertensive disorder><hypertensive disorder during pregnancy><hypertensive disorder in pregnancy><hypertensive disorder of pregnancy><imaging biomarker><imaging marker><imaging-based biological marker><imaging-based biomarker><imaging-based marker><improved><increase in blood pressure><increased blood pressure><inflammation marker><inflammatory marker><injuries><injury to the vasculature><insight><intervention research><interventional research><interventional study><interventions research><ketosis resistant diabetes><later in life><later life><maternal death><maternal morbidity><maturity onset diabetes><mortality><mortality among females><mortality among women><mortality in females><mortality in women><multidisciplinary><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><non-invasive imaging><noninvasive imaging><normotensive><novel><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><pathophysiology><perceived stress><perception of stress><post-partum><pre-eclamptic><pregnancy induced hypertensive disorder><pregnancy related hypertensive disease><pregnancy toxemia/hypertension><pregnancy-related complications><pregnancy-specific hypertensive disorder><prepregnancy><prevent><preventing><prognostic biomarker><prognostic indicator><programs><recruit><sadness><self reactive antibody><self-reported stress><sex><social><social health determinants><social role><sociobehavior><sociobehavioral><stress perception><systemic inflammation><systemic inflammatory response><type 2 DM><type II DM><type two diabetes><vascular><vascular dysfunction><vascular injury><vasculopathy><women at high risk><women's death><women's death rate><young woman><younger age>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Arthur Jason Vaught

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

Good lead · 54/100
Likely hiring
Above-average budget
Active award
$555,864
FY 2025

Project Title

Stress, inflammation and coronary endothelial injury in preeclampsia

Grant Number:

5R01HL159715-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/2/2022

End Date:

6/30/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

Hypertensive disorders of pregnancy, such as preeclampsia (PEC) cause significant maternal morbidity and mortality, and have emerged as an important early life, and potentially modifiable, risk factor of heart disease in younger women. PEC is diagnosed as new onset hypertension after 20 weeks gestat...

Research Terms

<ASCVD><Adult-Onset Diabetes Mellitus><Affect><Angiotensin AT1 Receptor><Angiotensin II Type 1 Receptor><Angiotensins><Atherosclerosis><Atherosclerotic Cardiovascular Disease><Autoantibodies><Biological><Biological Markers><Biology><Blood Diseases><Blood Vessels><COBRE><Cardiac Diseases><Cardiac Disorders><Cardiac infarction><Cardiology><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Cells Placenta-Tissue><Center of Biomedical Research Excellence><Centers of Research Excellence><Cessation of life><Clinic><Clinical><Communication><Coronary><Coronary Arteriosclerosis><Coronary Artery Disease><Coronary Artery Disorder><Coronary Atherosclerosis><Coronary Vessel Anomalies><Coronary abnormalities><Coronary anomalies><Coronary artery dysfunction><Coronary dysfunction><Data><Death><Depressed mood><Development><Diagnosis><Discipline of obstetrics><Disease><Disease Outcome><Disorder><Dysfunction><EPH Gestosis><Endocrine Gland Secretion><Endocrinology><Endothelial Cells><Endothelium><Event><Functional disorder><Funding><Future><Gender><Gender Role><General Population><General Public><Gestation><Health><Heart Diseases><Heart Vascular><Hematologic Diseases><Hematological Disease><Hematological Disorder><High Risk Woman><History><Hormones><Human><Hypertension><Hypertension-Associated Pregnancy Disorder><Imaging Procedures><Imaging Technics><Imaging Techniques><Impairment><Inflammation><Injury><Intervention><Intervention Studies><Ischemia><Ketosis-Resistant Diabetes Mellitus><Knowledge><Life><Link><Lived experience><Lived experiences><MR Imaging><MR Tomography><MRI><MRIs><Magnetic Resonance Imaging><Maternal Mortality><Maturity-Onset Diabetes Mellitus><Measures><Medical><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Metabolism and Endocrinology><Methods><Modern Man><Myocardial Infarct><Myocardial Infarction><NIDDM><NIH><NMR Imaging><NMR Tomography><National Institutes of Health><Neighborhoods><Nodal><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Normal Placentoma><Nuclear Magnetic Resonance Imaging><Obesity><Obstetrics><Organ><Outcome><Oxidative Stress><P50 Mechanism><P50 Program><Pathogenesis><Patients><Physiologic><Physiological><Physiopathology><Placenta><Placenta Embryonic Tissue><Placentome><Play><Population><Post-partum Women><Postpartum Hypertension><Postpartum Period><Postpartum Women><Pre-Eclampsia><Preeclampsia><Pregnancy><Pregnancy Complications><Pregnancy Toxemias><Prognostic Marker><Prospective Studies><Proteinuria-Edema-Hypertension Gestosis><Psychologic Stress><Psychological Stress><Psychosocial Stress><Public Health><Receptor, Angiotensin, Type 1><Recording of previous events><Renin-Angiotensin System><Reporting><Reproducibility><Research Resources><Resources><Risk><Risk Factors><Role><Severities><Sex Roles><Slow-Onset Diabetes Mellitus><Social Behavior><Specialized Center><Stable Diabetes Mellitus><Stratification><Stress><T2 DM><T2D><T2DM><Techniques><Testing><Therapeutic Hormone><Time><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><United States National Institutes of Health><Vascular Diseases><Vascular Disorder><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Woman><Women's mortality><Work><Zeugmatography><adiposity><adult onset diabetes><age group><angiogenesis><angiotensin II type I receptor><at-risk females><at-risk women><atheromatosis><atherosclerotic coronary disease><atherosclerotic disease><atherosclerotic vascular disease><autoimmune antibody><autoreactive antibody><bio-markers><biologic><biologic marker><biomarker><blood disorder><blood pressure elevation><blood vessel disorder><cardiac disease risk><cardiac disorder risk><cardiac infarct><cardioprotectant><cardioprotection><cardioprotective><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><cardiovascular health><cardiovascular risk><cardiovascular risk factor><circulatory system><cohort><compare to control><comparison control><complications during pregnancy><coronary arterial disease><coronary artery abnormalities><coronary artery anomalies><coronary attack><coronary infarct><coronary infarction><corpulence><death among females><death among women><death in females><death in women><death rate among women><death rate in women><depressed><design><designing><developmental><elevated blood pressure><endothelial dysfunction><experience><female death><female mortality><females at high risk><heart attack><heart disease risk><heart disorder><heart disorder risk><heart infarct><heart infarction><high blood pressure><high risk females><high risk group><high risk individual><high risk people><high risk population><histories><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disease during pregnancy><hypertensive disease in pregnancy><hypertensive disease of pregnancy><hypertensive disorder><hypertensive disorder during pregnancy><hypertensive disorder in pregnancy><hypertensive disorder of pregnancy><imaging biomarker><imaging marker><imaging-based biological marker><imaging-based biomarker><imaging-based marker><improved><increase in blood pressure><increased blood pressure><inflammation marker><inflammatory marker><injuries><injury to the vasculature><insight><intervention research><interventional research><interventional study><interventions research><ketosis resistant diabetes><later in life><later life><maternal death><maternal morbidity><maturity onset diabetes><mortality><mortality among females><mortality among women><mortality in females><mortality in women><multidisciplinary><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><non-invasive imaging><noninvasive imaging><normotensive><novel><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><pathophysiology><perceived stress><perception of stress><post-partum><pre-eclamptic><pregnancy induced hypertensive disorder><pregnancy related hypertensive disease><pregnancy toxemia/hypertension><pregnancy-related complications><pregnancy-specific hypertensive disorder><prepregnancy><prevent><preventing><prognostic biomarker><prognostic indicator><programs><recruit><sadness><self reactive antibody><self-reported stress><sex><social><social health determinants><social role><sociobehavior><sociobehavioral><stress perception><systemic inflammation><systemic inflammatory response><type 2 DM><type II DM><type two diabetes><vascular><vascular dysfunction><vascular injury><vasculopathy><women at high risk><women's death><women's death rate><young woman><younger age>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Melissa B Aldrich

UNIVERSITY OF TX MD ANDERSON CAN CTR, HOUSTON, TX

Good lead · 54/100
Likely hiring
Above-average budget
Active award
$507,876
FY 2025

Project Title

Lymphedema Prevention Through Immediate Lymphatic Reconstruction

Grant Number:

5R01CA292908-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/1/2024

End Date:

7/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT ABSTRACT Lymphedema is a debilitating, life-long iatrogenic sequalae of cancer treatment which is becoming an important survivorship issue due to improved cancer survival. Patients with inflammatory breast cancer (IBC), a highly aggressive form of breast cancer, require systemic therapy, sur...

Research Terms

<Address><Anatomic Sites><Anatomic structures><Anatomy><Architecture><Armpit><Axilla><Axillary><Axillary Lymph Node Dissection><Blood><Blood Plasma><Blood Reticuloendothelial System><Blood Serum><Breast Cancer><Breast Cancer Patient><Breast Tumor Patient><Bypass><Cancer Center><Cancer Research Programs><Cancer Research Project><Cancer Survivor><Cancer Treatment><Cell Body><Cells><Characteristics><Chemotactic Cytokines><Clinic><Clinical><Clinical Trials><Continuance of life><Development><Diagnosis><Engineering / Architecture><Extremities><Fluorescence><Homologous Chemotactic Cytokines><Iatrogenesis><Image><Immune><Immunes><Incidence><Indocyanine Green><Inflammation><Inflammatory><Intercrines><Intervention><Investigation><Limb structure><Limbs><Lymph><Lymph Node Dissections><Lymph Node Reticuloendothelial System><Lymph node excision><Lymph node proper><Lymphadenectomy><Lymphatic><Lymphatic nodes><Lymphedema><Malignant Breast Neoplasm><Malignant Neoplasm Therapy><Malignant Neoplasm Treatment><Measurement><Meta-Analysis><Microsurgery><Modality><Newly Diagnosed><Non-Trunk><Oncology><Oncology Cancer><Operative Procedures><Operative Surgical Procedures><Outcome><Outcome Assessment><Outcome Measure><P50 Mechanism><P50 Program><Patient Care><Patient Care Delivery><Patient Outcomes Assessments><Patient Reported Measures><Patient Reported Outcomes><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Pattern><Personal Satisfaction><Persons><Physiatric Procedure><Physical Medicine Procedure><Physical Therapeutics><Physical therapy><Physiotherapy><Plasma><Plasma Serum><Prevention><Procedures><Publishing><Pump><QOL improvement><Radiation therapy><Radiotherapeutics><Radiotherapy><Reconstructive Surgical Procedures><Reporting><Reticuloendothelial System, Serum, Plasma><Risk><Risk Reduction><SIS cytokines><SYS-TX><Sampling><Serum><Specialized Center><Spectroscopy><Spectrum Analyses><Spectrum Analysis><Surgical><Surgical Interventions><Surgical Procedure><Survivorship Issues><Swelling><Symptom Burden><Systemic Therapy><Techniques><Time><Transplantation Surgery><Ujoveridin><Underarm><Vascularization><Veins><Visualization><Wofaverdin><Work><analyzing longitudinal><anti-cancer therapy><arm><axillary dissection><biomarker array><biomarker identification><biomarker panel><cancer surgery><cancer survival><cancer therapy><cancer-directed therapy><care for patients><care of patients><caring for patients><chemoattractant cytokine><chemokine><clinical diagnosis><cohort><cytokine><developmental><high risk><high risk group><high risk individual><high risk people><high risk population><iatrogenic><iatrogenically><iatrogenicity><identification of biomarkers><identification of new biomarkers><imaging><improved><improvements in QOL><improvements in quality of life><individuals with breast cancer><inflammation marker><inflammatory breast cancer><inflammatory marker><longitudinal analysis><lymph channel><lymph edema><lymph gland><lymph nodes><lymph vessel><lymphatic channel><lymphatic edema><lymphatic fluid><lymphatic imaging><lymphatic vessel><lymphnodes><malignant breast tumor><marker identification><marker panel><measurable outcome><outcome measurement><patient oriented outcomes><patient population><patient profile><patients with breast cancer><peripheral blood><person with breast cancer><potential biological marker><potential biomarker><predictive biological marker><predictive biomarkers><predictive marker><predictive molecular biomarker><prevent><preventing><profiles in patients><quality of life improvement><radiation treatment><reconstruction><reconstruction surgery><reconstructive surgery><recruit><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><risk-reducing><standard of care><surgery><treatment center><treatment with radiation><well-being><wellbeing>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Mark V Schaverien

UNIVERSITY OF TX MD ANDERSON CAN CTR, HOUSTON, TX

Good lead · 54/100
Likely hiring
Above-average budget
Active award
$507,876
FY 2025

Project Title

Lymphedema Prevention Through Immediate Lymphatic Reconstruction

Grant Number:

5R01CA292908-02

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/1/2024

End Date:

7/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.
  • • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT ABSTRACT Lymphedema is a debilitating, life-long iatrogenic sequalae of cancer treatment which is becoming an important survivorship issue due to improved cancer survival. Patients with inflammatory breast cancer (IBC), a highly aggressive form of breast cancer, require systemic therapy, sur...

Research Terms

<Address><Anatomic Sites><Anatomic structures><Anatomy><Architecture><Armpit><Axilla><Axillary><Axillary Lymph Node Dissection><Blood><Blood Plasma><Blood Reticuloendothelial System><Blood Serum><Breast Cancer><Breast Cancer Patient><Breast Tumor Patient><Bypass><Cancer Center><Cancer Research Programs><Cancer Research Project><Cancer Survivor><Cancer Treatment><Cell Body><Cells><Characteristics><Chemotactic Cytokines><Clinic><Clinical><Clinical Trials><Continuance of life><Development><Diagnosis><Engineering / Architecture><Extremities><Fluorescence><Homologous Chemotactic Cytokines><Iatrogenesis><Image><Immune><Immunes><Incidence><Indocyanine Green><Inflammation><Inflammatory><Intercrines><Intervention><Investigation><Limb structure><Limbs><Lymph><Lymph Node Dissections><Lymph Node Reticuloendothelial System><Lymph node excision><Lymph node proper><Lymphadenectomy><Lymphatic><Lymphatic nodes><Lymphedema><Malignant Breast Neoplasm><Malignant Neoplasm Therapy><Malignant Neoplasm Treatment><Measurement><Meta-Analysis><Microsurgery><Modality><Newly Diagnosed><Non-Trunk><Oncology><Oncology Cancer><Operative Procedures><Operative Surgical Procedures><Outcome><Outcome Assessment><Outcome Measure><P50 Mechanism><P50 Program><Patient Care><Patient Care Delivery><Patient Outcomes Assessments><Patient Reported Measures><Patient Reported Outcomes><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Pattern><Personal Satisfaction><Persons><Physiatric Procedure><Physical Medicine Procedure><Physical Therapeutics><Physical therapy><Physiotherapy><Plasma><Plasma Serum><Prevention><Procedures><Publishing><Pump><QOL improvement><Radiation therapy><Radiotherapeutics><Radiotherapy><Reconstructive Surgical Procedures><Reporting><Reticuloendothelial System, Serum, Plasma><Risk><Risk Reduction><SIS cytokines><SYS-TX><Sampling><Serum><Specialized Center><Spectroscopy><Spectrum Analyses><Spectrum Analysis><Surgical><Surgical Interventions><Surgical Procedure><Survivorship Issues><Swelling><Symptom Burden><Systemic Therapy><Techniques><Time><Transplantation Surgery><Ujoveridin><Underarm><Vascularization><Veins><Visualization><Wofaverdin><Work><analyzing longitudinal><anti-cancer therapy><arm><axillary dissection><biomarker array><biomarker identification><biomarker panel><cancer surgery><cancer survival><cancer therapy><cancer-directed therapy><care for patients><care of patients><caring for patients><chemoattractant cytokine><chemokine><clinical diagnosis><cohort><cytokine><developmental><high risk><high risk group><high risk individual><high risk people><high risk population><iatrogenic><iatrogenically><iatrogenicity><identification of biomarkers><identification of new biomarkers><imaging><improved><improvements in QOL><improvements in quality of life><individuals with breast cancer><inflammation marker><inflammatory breast cancer><inflammatory marker><longitudinal analysis><lymph channel><lymph edema><lymph gland><lymph nodes><lymph vessel><lymphatic channel><lymphatic edema><lymphatic fluid><lymphatic imaging><lymphatic vessel><lymphnodes><malignant breast tumor><marker identification><marker panel><measurable outcome><outcome measurement><patient oriented outcomes><patient population><patient profile><patients with breast cancer><peripheral blood><person with breast cancer><potential biological marker><potential biomarker><predictive biological marker><predictive biomarkers><predictive marker><predictive molecular biomarker><prevent><preventing><profiles in patients><quality of life improvement><radiation treatment><reconstruction><reconstruction surgery><reconstructive surgery><recruit><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><risk-reducing><standard of care><surgery><treatment center><treatment with radiation><well-being><wellbeing>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

JOSEPH D DOUGHERTY

WASHINGTON UNIVERSITY, SAINT LOUIS, MO

Good lead · 54/100
Likely hiring
Solid budget
Active award
Team-scale grant
$250,000
FY 2025

Project Title

WASHINGTON UNIVERSITY INTELLECTUAL AND DEVELOPMENTAL DISABILITIES RESEARCH CENTER

Grant Number:

3P50HD103525-05S4

Activity Code:

P50

Mechanism:

Research Centers

Agency:

NIH

Start Date:

7/12/2025

End Date:

5/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

Overall Project Abstract For the third cycle of the Intellectual and Developmental Disabilities Research Center at Washington University, we propose a next phase in a comprehensive approach to understanding, ameliorating, and/or preventing neurodevelopmental disability through translational scientif...

Research Terms

<0-11 years old><ASD><Active Follow-up><Affect><Animal Model><Animal Models and Related Studies><Autism><Autistic Disorder><Behavior><Behavioral><Biocompatible Materials><Bioinformatics><Biologic Models><Biological Markers><Biological Models><Biomaterials><Brain><Brain Nervous System><Brain imaging><Caliber><Calibration><Causality><Cell Body><Cell Line><Cell model><CellLine><Cells><Cellular model><Child><Child Development Disorders><Child Youth><Children (0-21)><Clinical><Clinical Trials><Collection><Communities><Core Facility><Data><Data Set><Dedications><Derivation><Derivation procedure><Development><Developmental Disabilities><Disability research><Disability study><Disease><Disorder><Disparate><Down Syndrome><Dysfunction><EXTMR><Early Infantile Autism><Electronic Health Record><Encephalon><Enrollment><Equipment and supply inventories><Etiology><Extramural><Extramural Activities><Faculty><Familial disease><Family><Functional disorder><Funding><Gene Copy Number><Gene Dosage><Gene variant><Generations><Genes><Genetic><Genomics><Goals><Human><IDDRC><IDDRP><Image><Individual><Infant><Infantile Autism><Institution><Intellectual and Developmental Disabilities Research Centers><Intellectual disability><Intellectual functioning disability><Intellectual limitation><Interruption><Intervention><Inventory><Investigation><Investigators><Kanner's Syndrome><Knowledge><Langdon Down syndrome><Longitudinal Studies><MRDD Research Center><MRDDRC><Mental Retardation and Developmental Disabilities Research Centers><Methods><Model System><Modern Man><Molecular><Mongolism><Mothers><NIH><National Institutes of Health><Natural History><Neurodevelopmental Disability><Neurosciences><P50 Mechanism><P50 Program><Pathogenesis><Pathway interactions><Patients><Phase><Phenotype><Physiopathology><Population><Preventative intervention><Prevention><Productivity><QOL><Qualifying><Quality of life><R-Series Research Projects><R01 Mechanism><R01 Program><Registries><Research><Research Grants><Research Infrastructure><Research Personnel><Research Project Grants><Research Projects><Research Resources><Research on disabilities><Researchers><Resources><Risk><Rodent Model><Science><Scientist><Site><Specialized Center><Specific qualifier value><Specified><Standardization><Strains Cell Lines><Structure><Study on disabilities><Synapses><Synaptic><Syndrome><Therapeutic><Translating><Translational Research><Translational Science><Translations><Trisomy 21><United States National Institutes of Health><Universities><Variant><Variation><Washington><active followup><allelic variant><autism spectral disorder><autism spectrum disorder><autistic spectrum disorder><behavior phenotype><behavioral phenotyping><bio-markers><biologic marker><biological material><biomarker><brain visualization><causation><chromosome 21 trisomy><chromosome 21 trisomy syndrome><clinical translation><clinically translatable><cognitive neuroscience><cohort><congenital acromicria syndrome><cultured cell line><developmental><discover genes><disease causation><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><enroll><familial disorder><follow up><follow-up><followed up><followup><functional genomics><gene discovery><genetic variant><genomic variant><imaging><imaging study><intellectual and developmental disability><intervention for prevention><kids><limited intellectual functioning><long-term study><longitudinal outcome studies><low-frequency mutation><medical college><medical schools><model of animal><morbus Down><multiomics><multiple omics><neural><neural imaging><neuro-imaging><neuroimaging><neurological imaging><new drug target><new drug treatments><new druggable target><new drugs><new pharmacological therapeutic><new pharmacotherapy target><new therapeutic target><new therapeutics><new therapy><new therapy target><next generation therapeutics><novel><novel drug target><novel drug treatments><novel druggable target><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel pharmacotherapy target><novel therapeutic target><novel therapeutics><novel therapy><novel therapy target><panomics><pathophysiology><pathway><patient population><premature><prematurity><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><programs><prospective><pseudohypertrophic progressive muscular dystrophy><psychosocial><rare allele><rare mutation><rare variant><school of medicine><success><synapse><synergism><translation><translation research><translational investigation><trisomy 21 syndrome><work group><working group><youngster>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Christina Gurnett

WASHINGTON UNIVERSITY, SAINT LOUIS, MO

Good lead · 54/100
Likely hiring
Solid budget
Active award
Team-scale grant
$250,000
FY 2025

Project Title

WASHINGTON UNIVERSITY INTELLECTUAL AND DEVELOPMENTAL DISABILITIES RESEARCH CENTER

Grant Number:

3P50HD103525-05S4

Activity Code:

P50

Mechanism:

Research Centers

Agency:

NIH

Start Date:

7/12/2025

End Date:

5/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

Overall Project Abstract For the third cycle of the Intellectual and Developmental Disabilities Research Center at Washington University, we propose a next phase in a comprehensive approach to understanding, ameliorating, and/or preventing neurodevelopmental disability through translational scientif...

Research Terms

<0-11 years old><ASD><Active Follow-up><Affect><Animal Model><Animal Models and Related Studies><Autism><Autistic Disorder><Behavior><Behavioral><Biocompatible Materials><Bioinformatics><Biologic Models><Biological Markers><Biological Models><Biomaterials><Brain><Brain Nervous System><Brain imaging><Caliber><Calibration><Causality><Cell Body><Cell Line><Cell model><CellLine><Cells><Cellular model><Child><Child Development Disorders><Child Youth><Children (0-21)><Clinical><Clinical Trials><Collection><Communities><Core Facility><Data><Data Set><Dedications><Derivation><Derivation procedure><Development><Developmental Disabilities><Disability research><Disability study><Disease><Disorder><Disparate><Down Syndrome><Dysfunction><EXTMR><Early Infantile Autism><Electronic Health Record><Encephalon><Enrollment><Equipment and supply inventories><Etiology><Extramural><Extramural Activities><Faculty><Familial disease><Family><Functional disorder><Funding><Gene Copy Number><Gene Dosage><Gene variant><Generations><Genes><Genetic><Genomics><Goals><Human><IDDRC><IDDRP><Image><Individual><Infant><Infantile Autism><Institution><Intellectual and Developmental Disabilities Research Centers><Intellectual disability><Intellectual functioning disability><Intellectual limitation><Interruption><Intervention><Inventory><Investigation><Investigators><Kanner's Syndrome><Knowledge><Langdon Down syndrome><Longitudinal Studies><MRDD Research Center><MRDDRC><Mental Retardation and Developmental Disabilities Research Centers><Methods><Model System><Modern Man><Molecular><Mongolism><Mothers><NIH><National Institutes of Health><Natural History><Neurodevelopmental Disability><Neurosciences><P50 Mechanism><P50 Program><Pathogenesis><Pathway interactions><Patients><Phase><Phenotype><Physiopathology><Population><Preventative intervention><Prevention><Productivity><QOL><Qualifying><Quality of life><R-Series Research Projects><R01 Mechanism><R01 Program><Registries><Research><Research Grants><Research Infrastructure><Research Personnel><Research Project Grants><Research Projects><Research Resources><Research on disabilities><Researchers><Resources><Risk><Rodent Model><Science><Scientist><Site><Specialized Center><Specific qualifier value><Specified><Standardization><Strains Cell Lines><Structure><Study on disabilities><Synapses><Synaptic><Syndrome><Therapeutic><Translating><Translational Research><Translational Science><Translations><Trisomy 21><United States National Institutes of Health><Universities><Variant><Variation><Washington><active followup><allelic variant><autism spectral disorder><autism spectrum disorder><autistic spectrum disorder><behavior phenotype><behavioral phenotyping><bio-markers><biologic marker><biological material><biomarker><brain visualization><causation><chromosome 21 trisomy><chromosome 21 trisomy syndrome><clinical translation><clinically translatable><cognitive neuroscience><cohort><congenital acromicria syndrome><cultured cell line><developmental><discover genes><disease causation><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><enroll><familial disorder><follow up><follow-up><followed up><followup><functional genomics><gene discovery><genetic variant><genomic variant><imaging><imaging study><intellectual and developmental disability><intervention for prevention><kids><limited intellectual functioning><long-term study><longitudinal outcome studies><low-frequency mutation><medical college><medical schools><model of animal><morbus Down><multiomics><multiple omics><neural><neural imaging><neuro-imaging><neuroimaging><neurological imaging><new drug target><new drug treatments><new druggable target><new drugs><new pharmacological therapeutic><new pharmacotherapy target><new therapeutic target><new therapeutics><new therapy><new therapy target><next generation therapeutics><novel><novel drug target><novel drug treatments><novel druggable target><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel pharmacotherapy target><novel therapeutic target><novel therapeutics><novel therapy><novel therapy target><panomics><pathophysiology><pathway><patient population><premature><prematurity><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><programs><prospective><pseudohypertrophic progressive muscular dystrophy><psychosocial><rare allele><rare mutation><rare variant><school of medicine><success><synapse><synergism><translation><translation research><translational investigation><trisomy 21 syndrome><work group><working group><youngster>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

JOSEPH D DOUGHERTY

WASHINGTON UNIVERSITY, SAINT LOUIS, MO

Good lead · 54/100
Likely hiring
Solid budget
Active award
Team-scale grant
$250,000
FY 2025

Project Title

Washington University Intellectual and Developmental Disabilities Research Center

Grant Number:

3P50HD103525-05S3

Activity Code:

P50

Mechanism:

Research Centers

Agency:

NIH

Start Date:

7/28/2020

End Date:

5/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

Overall Project Abstract For the third cycle of the Intellectual and Developmental Disabilities Research Center at Washington University, we propose a next phase in a comprehensive approach to understanding, ameliorating, and/or preventing neurodevelopmental disability through translational scientif...

Research Terms

<0-11 years old><ASD><Active Follow-up><Affect><Animal Model><Animal Models and Related Studies><Autism><Autistic Disorder><Behavior><Behavioral><Biocompatible Materials><Bioinformatics><Biologic Models><Biological Markers><Biological Models><Biomaterials><Brain><Brain Nervous System><Brain imaging><Caliber><Calibration><Causality><Cell Body><Cell Line><Cell model><CellLine><Cells><Cellular model><Child><Child Development Disorders><Child Youth><Children (0-21)><Clinical><Clinical Trials><Collection><Communities><Core Facility><Data><Data Set><Dedications><Derivation><Derivation procedure><Development><Developmental Disabilities><Disability research><Disability study><Disease><Disorder><Disparate><Down Syndrome><Dysfunction><EXTMR><Early Infantile Autism><Electronic Health Record><Encephalon><Enrollment><Equipment and supply inventories><Etiology><Extramural><Extramural Activities><Faculty><Familial disease><Family><Functional disorder><Funding><Gene Copy Number><Gene Dosage><Gene variant><Generations><Genes><Genetic><Genomics><Goals><Human><IDDRC><IDDRP><Image><Individual><Infant><Infantile Autism><Institution><Intellectual and Developmental Disabilities Research Centers><Intellectual disability><Intellectual functioning disability><Intellectual limitation><Interruption><Intervention><Inventory><Investigation><Investigators><Kanner's Syndrome><Knowledge><Langdon Down syndrome><Longitudinal Studies><MRDD Research Center><MRDDRC><Mental Retardation and Developmental Disabilities Research Centers><Methods><Model System><Modern Man><Molecular><Mongolism><Mothers><NIH><National Institutes of Health><Natural History><Neurodevelopmental Disability><Neurosciences><P50 Mechanism><P50 Program><Pathogenesis><Pathway interactions><Patients><Phase><Phenotype><Physiopathology><Population><Preventative intervention><Prevention><Productivity><QOL><Qualifying><Quality of life><R-Series Research Projects><R01 Mechanism><R01 Program><Registries><Research><Research Grants><Research Infrastructure><Research Personnel><Research Project Grants><Research Projects><Research Resources><Research on disabilities><Researchers><Resources><Risk><Rodent Model><Science><Scientist><Site><Specialized Center><Specific qualifier value><Specified><Standardization><Strains Cell Lines><Structure><Study on disabilities><Synapses><Synaptic><Syndrome><Therapeutic><Translating><Translational Research><Translational Science><Translations><Trisomy 21><United States National Institutes of Health><Universities><Variant><Variation><Washington><active followup><allelic variant><autism spectral disorder><autism spectrum disorder><autistic spectrum disorder><behavior phenotype><behavioral phenotyping><bio-markers><biologic marker><biological material><biomarker><brain visualization><causation><chromosome 21 trisomy><chromosome 21 trisomy syndrome><clinical translation><clinically translatable><cognitive neuroscience><cohort><congenital acromicria syndrome><cultured cell line><developmental><discover genes><disease causation><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><enroll><familial disorder><follow up><follow-up><followed up><followup><functional genomics><gene discovery><genetic variant><genomic variant><imaging><imaging study><intellectual and developmental disability><intervention for prevention><kids><limited intellectual functioning><long-term study><longitudinal outcome studies><low-frequency mutation><medical college><medical schools><model of animal><morbus Down><multiomics><multiple omics><neural><neural imaging><neuro-imaging><neuroimaging><neurological imaging><new drug target><new drug treatments><new druggable target><new drugs><new pharmacological therapeutic><new pharmacotherapy target><new therapeutic target><new therapeutics><new therapy><new therapy target><next generation therapeutics><novel><novel drug target><novel drug treatments><novel druggable target><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel pharmacotherapy target><novel therapeutic target><novel therapeutics><novel therapy><novel therapy target><panomics><pathophysiology><pathway><patient population><premature><prematurity><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><programs><prospective><pseudohypertrophic progressive muscular dystrophy><psychosocial><rare allele><rare mutation><rare variant><school of medicine><success><synapse><synergism><translation><translation research><translational investigation><trisomy 21 syndrome><work group><working group><youngster>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Christina Gurnett

WASHINGTON UNIVERSITY, SAINT LOUIS, MO

Good lead · 54/100
Likely hiring
Solid budget
Active award
Team-scale grant
$250,000
FY 2025

Project Title

Washington University Intellectual and Developmental Disabilities Research Center

Grant Number:

3P50HD103525-05S3

Activity Code:

P50

Mechanism:

Research Centers

Agency:

NIH

Start Date:

7/28/2020

End Date:

5/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

Overall Project Abstract For the third cycle of the Intellectual and Developmental Disabilities Research Center at Washington University, we propose a next phase in a comprehensive approach to understanding, ameliorating, and/or preventing neurodevelopmental disability through translational scientif...

Research Terms

<0-11 years old><ASD><Active Follow-up><Affect><Animal Model><Animal Models and Related Studies><Autism><Autistic Disorder><Behavior><Behavioral><Biocompatible Materials><Bioinformatics><Biologic Models><Biological Markers><Biological Models><Biomaterials><Brain><Brain Nervous System><Brain imaging><Caliber><Calibration><Causality><Cell Body><Cell Line><Cell model><CellLine><Cells><Cellular model><Child><Child Development Disorders><Child Youth><Children (0-21)><Clinical><Clinical Trials><Collection><Communities><Core Facility><Data><Data Set><Dedications><Derivation><Derivation procedure><Development><Developmental Disabilities><Disability research><Disability study><Disease><Disorder><Disparate><Down Syndrome><Dysfunction><EXTMR><Early Infantile Autism><Electronic Health Record><Encephalon><Enrollment><Equipment and supply inventories><Etiology><Extramural><Extramural Activities><Faculty><Familial disease><Family><Functional disorder><Funding><Gene Copy Number><Gene Dosage><Gene variant><Generations><Genes><Genetic><Genomics><Goals><Human><IDDRC><IDDRP><Image><Individual><Infant><Infantile Autism><Institution><Intellectual and Developmental Disabilities Research Centers><Intellectual disability><Intellectual functioning disability><Intellectual limitation><Interruption><Intervention><Inventory><Investigation><Investigators><Kanner's Syndrome><Knowledge><Langdon Down syndrome><Longitudinal Studies><MRDD Research Center><MRDDRC><Mental Retardation and Developmental Disabilities Research Centers><Methods><Model System><Modern Man><Molecular><Mongolism><Mothers><NIH><National Institutes of Health><Natural History><Neurodevelopmental Disability><Neurosciences><P50 Mechanism><P50 Program><Pathogenesis><Pathway interactions><Patients><Phase><Phenotype><Physiopathology><Population><Preventative intervention><Prevention><Productivity><QOL><Qualifying><Quality of life><R-Series Research Projects><R01 Mechanism><R01 Program><Registries><Research><Research Grants><Research Infrastructure><Research Personnel><Research Project Grants><Research Projects><Research Resources><Research on disabilities><Researchers><Resources><Risk><Rodent Model><Science><Scientist><Site><Specialized Center><Specific qualifier value><Specified><Standardization><Strains Cell Lines><Structure><Study on disabilities><Synapses><Synaptic><Syndrome><Therapeutic><Translating><Translational Research><Translational Science><Translations><Trisomy 21><United States National Institutes of Health><Universities><Variant><Variation><Washington><active followup><allelic variant><autism spectral disorder><autism spectrum disorder><autistic spectrum disorder><behavior phenotype><behavioral phenotyping><bio-markers><biologic marker><biological material><biomarker><brain visualization><causation><chromosome 21 trisomy><chromosome 21 trisomy syndrome><clinical translation><clinically translatable><cognitive neuroscience><cohort><congenital acromicria syndrome><cultured cell line><developmental><discover genes><disease causation><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><enroll><familial disorder><follow up><follow-up><followed up><followup><functional genomics><gene discovery><genetic variant><genomic variant><imaging><imaging study><intellectual and developmental disability><intervention for prevention><kids><limited intellectual functioning><long-term study><longitudinal outcome studies><low-frequency mutation><medical college><medical schools><model of animal><morbus Down><multiomics><multiple omics><neural><neural imaging><neuro-imaging><neuroimaging><neurological imaging><new drug target><new drug treatments><new druggable target><new drugs><new pharmacological therapeutic><new pharmacotherapy target><new therapeutic target><new therapeutics><new therapy><new therapy target><next generation therapeutics><novel><novel drug target><novel drug treatments><novel druggable target><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel pharmacotherapy target><novel therapeutic target><novel therapeutics><novel therapy><novel therapy target><panomics><pathophysiology><pathway><patient population><premature><prematurity><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><programs><prospective><pseudohypertrophic progressive muscular dystrophy><psychosocial><rare allele><rare mutation><rare variant><school of medicine><success><synapse><synergism><translation><translation research><translational investigation><trisomy 21 syndrome><work group><working group><youngster>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Robert Koehler Abbott

UNIVERSITY OF TEXAS MED BR GALVESTON, GALVESTON, TX

Good lead · 52/100
Likely hiring
Solid budget
Active award
$480,000
FY 2026

Project Title

Revealing the Biophysics of the Germinal Center Microenvironment

Grant Number:

5DP2AI154410-05

Activity Code:

DP2

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/22/2021

End Date:

11/30/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

Abstract Is an HIV vaccine possible? Vaccines are one of the most successful public health interventions over the past century. Nearly all vaccines work by induction of protective antibodies. However, our understanding of the cellular dynamics of immune responses to vaccines, particularly the biolog...

Research Terms

<A2AR><ADORA2><ADORA2A gene><AIDS Vaccines><AIDS Virus><AIDS vaccine><Achievement><Achievement Attainment><Acquired Immune Deficiency Syndrome Virus><Acquired Immunodeficiency Syndrome Virus><Address><Adenosine><Adenosine A(2A) Receptor><Adenosine A2A Receptor><Adenosine Receptors><Affect><Affinity><Animal Model><Animal Models and Related Studies><Antibodies><Antibody Response><Antigenic Determinants><Antigens><Autoimmune Status><Autoimmunity><Avidity><B blood cells><B cell><B cell receptor><B cells><B-Cell Activation><B-Cell Antigen Receptor><B-Cells><B-Lymphocytes><B-cell><Binding Determinants><Biologic Models><Biological Models><Biology><Biophysics><Cell Communication and Signaling><Cell Culture Techniques><Cell Signaling><Cell model><Cellular biology><Cellular model><Characteristics><Clone Cells><Coin><Complex><Cues><Drug Therapy><Engineering><Env trimer><Epitopes><Event><Extracellular Space><Frequencies><Future><G Protein-Complex Receptor><G Protein-Coupled Receptor Genes><G-Protein-Coupled Receptors><GPCR><Generations><Genes><Germ Lines><Germinal Center><Goals><HIV><HIV Env><HIV Seronegativities><HIV Seronegativity><HIV envelope><HIV envelope protein><HIV glycoprotein Env><HIV individuals><HIV infected individuals><HIV infected persons><HIV negative><HIV people><HIV positive individuals><HIV positive people><HIV vaccine><HIV-1 Env><HIV-1 envelope><HIV-1 glycoprotein Env><HIV/AIDS Vaccines><HTLV-III Seronegativities><HTLV-III Seronegativity><Helper Cells><Helper T-Cells><Helper T-Lymphocytes><Helper-Inducer T-Cells><Helper-Inducer T-Lymphocyte><Human><Human Immunodeficiency Viruses><Hypoxia><Hypoxic><Hypoxic tumor><Ig Somatic Hypermutation><Immune response><Immunization><Immunochemical Immunologic><Immunoglobulin Somatic Hypermutation><Immunologic><Immunological><Immunologically><Immunologics><Immunomodulation><In Vitro><Individual><Inducer Cells><Inducer T-Lymphocytes><Influenza HA><Influenza Hemagglutinin><Intercellular Space><Intracellular Communication and Signaling><Island><Knowledge><LAV-HTLV-III><Learning><Licensing><Lymphadenopathy-Associated Virus><Measurement><Measures><Metabolic><Metabolic Pathway><Mice><Mice Mammals><Microdialysis><Microscopic><Model System><Modeling><Modern Man><Murine><Mus><Mutate><Nature><Outcome><Oxygen Deficiency><P1 Purinoceptors><P50 Mechanism><P50 Program><PLWH><PWH><Pathway interactions><Pharmacological Treatment><Pharmacotherapy><Phase><Phylogenetic Analysis><Phylogenetics><Physiologic><Physiological><Play><Population><Purinergic P1 Receptors><RDC8><Reaction><Role><Series><Signal Transduction><Signal Transduction Systems><Signaling><Specialized Center><Structure><Structure of germinal center of lymph node><System><Temperature><VEGF><VEGFs><Vaccination><Vaccine Antigen><Vaccine Design><Vaccines><Vascular Endothelial Growth Factors><Virus><Virus-HIV><Work><activated B cells><biological signal transduction><biophysical characteristics><biophysical characterization><biophysical foundation><biophysical measurement><biophysical parameters><biophysical principles><biophysical properties><biophysical sciences><cancer microenvironment><cell biology><cell culture><cell cultures><design><designing><drug intervention><drug treatment><extracellular><fitness><flu HA><flu hemagglutinin><host response><human immunodeficiency virus vaccine><immune modulation><immune regulation><immune response to vaccination><immune response to vaccines><immune system response><immunogen><immunologic reactivity control><immunomodulatory><immunoregulation><immunoregulatory><immunoresponse><improved><individuals infected with HIV><individuals with HIV><individuals with human immunodeficiency virus><influenza viral HA><influenza viral hemagglutinin><influenza virus HA><influenza virus hemagglutinin><insight><interest><model of animal><multi-photon><neutralizing antibody><novel><pathway><people infected with HIV><people infected with human immunodeficiency virus><people living with HIV><people with HIV><people with human immunodeficiency virus><pharmaceutical intervention><pharmacologic><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><pressure><public health intervention><recruit><response><small molecule><social role><somatic hypermutation><success><tumor hypoxia><tumor microenvironment><vaccine against HIV><vaccine associated immune response><vaccine immune response><vaccine immunogenicity><vaccine induced immune response>
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Chandrashekhar Pasare

CINCINNATI CHILDRENS HOSP MED CTR, CINCINNATI, OH

Good lead · 52/100
Likely hiring
Solid budget
Active award
$477,000
FY 2026

Project Title

Innate mechanisms of regulation of Th17 responses

Grant Number:

5R01AI123176-10

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

12/1/2016

End Date:

12/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

Project Summary/Abstract Induction of inflammation by canonical microbial ligands by engaging classical patten recognition receptors (PRR) has many beneficial outcomes including elimination of the pathogen and activation of adaptive immunity that serves as protection against reinfection. However, un...

Research Terms

<(TNF)-α><ATM Protein><ATM Serine/Threonine Protein Kinase><ATM kinase><ATM protein kinase><Adaptive Immune System><Apoptosis-Related Cysteine Protease Gene Caspase 8><Apoptotic Cysteine Protease Gene><Apoptotic Protease MCH-5 Gene><Ataxia Telangiectasia Mutated><Ataxia Telangiectasia Protein><Ataxia-Telangiectasia-Mutated protein kinase><Autoimmune><Autoimmune Diseases><Autoimmune Status><Autoimmunity><Automobile Driving><B blood cells><B cell><B cells><B-Cells><B-Lymphocytes><B-cell><Bacteria><Body Tissues><Bp50><Bypass><CAP4><CAP4 protease><CASP8><CASP8 Protein><CASP8 gene><CD4 Cells><CD4 Positive T Lymphocytes><CD4 T cells><CD4 helper T cell><CD4 lymphocyte><CD4+ T-Lymphocyte><CD4-Positive Lymphocytes><CD40><CDW40><Cachectin><Cachectin Receptors><Caspase-8 Gene><Caspase-8/Flice><Cell Body><Cell Communication><Cell Communication and Signaling><Cell Interaction><Cell Lineage><Cell Signaling><Cell-to-Cell Interaction><Cells><Chemotactic Cytokines><Clinical Treatment><Clonal Expansion><Code><Coding System><Cues><DNA Damage><DNA Injury><DNA mutation><Data><Dendritic Cells><Disease><Disorder><Event><Expression Signature><FADD-Homologous ICE/CED3-Like Protease Gene><FADD-Like ICE><FADD-Like ICE Gene><FADD-homologous ICE/CED3-Like Protease><FLICE><FLICE protein><Gene Expression Profile><Generations><Genes><Genetic Change><Genetic defect><Genetic mutation><Homologous Chemotactic Cytokines><ICE-Like Apoptotic Protease 5 Gene><IFN><IL1R><IL1R1><IL1R1 gene><IL1RA><Infection><Inflammasome><Inflammation><Inflammatory><Inflammatory Response><Innate Immune System><Innate Immunity><Instruction><Intercrines><Interferons><Intestinal><Intestines><Intracellular Communication and Signaling><Invaded><Investigation><Joints><Kidney><Kidney Urinary System><Ligands><Lymphatic Tissue><Lymphoid Tissue><MACH protein><MACH-Alpha-1/2/3 Protein Gene><MACH-Beta-1/2/3/4 Protein Gene><MCH5><MCH5 Isoform Alpha Gene><MGC9013><MORT1-Associated CED-3 Homolog Gene><MORT1-Associated CED3 Homolog Gene><Macrophage><Macrophage-Derived TNF><Mch5 protease><Memory><Molecular><Monocyte-Derived TNF><Morbidity><Mutation><Myeloid Cells><Mφ><Native Immunity><Natural Immunity><Nature><Non-Specific Immunity><Nonspecific Immunity><Nuclear><Organ><Outcome><Pancreas><Pancreatic><Pathologic><Pathology><Pathway interactions><Pattern recognition receptor><Peptide-MHC><Peptide-Major Histocompatibility Protein Complex><Peptide/MHC Complex><Peptides><Play><Population><Process><Production><Receptor Activation><Receptor Protein><Regulation><Role><SIS cytokines><Signal Transduction><Signal Transduction Systems><Signaling><Skin><Stimulator of Interferon Genes><Surface><Syndrome><T memory cell><T-Cell Activation><T-Cells><T-Lymphocyte><T4 Cells><T4 Lymphocytes><TEM cells><TNF><TNF A><TNF Alpha><TNF Receptor Family Protein><TNF Receptor Superfamily><TNF Receptors><TNF gene><TNF-α><TNFA><TNFR><TNFRSF5><TNFRSF5 gene><TNFα><Teff cell><Tissues><Toxin><Transmission><Trioxopurine><Tumor Necrosis Factor><Tumor Necrosis Factor Receptor><Tumor Necrosis Factor Receptor Family><Tumor Necrosis Factor Receptor Superfamily><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><Tumor Necrosis Factor-alpha><Upregulation><Uric Acid><Veiled Cells><Virus><Work><acquired immune system><activate T cells><adaptive immunity><arm><ataxia telangiectasia mutated protein><autoimmune condition><autoimmune disorder><autoimmune inflammation><autoimmune reactivity><autoimmunity disease><autoinflammatory diseases><autoinflammatory disorders><autoreactive T cell><autoreactivity><biological signal transduction><bowel><cGAMP STING><cGAMP-STING><cGAMP/STING><cGAS/STING><caspase-8><chemoattractant cytokine><chemokine><clinical intervention><clinical therapy><cyclic GMP-AMP synthase/STING><cytokine><cytokine release syndrome><cytokine storm><driving><effector T cell><fungus><gene expression pattern><gene expression signature><genome mutation><in vivo><insight><member><memory CD4 T cell><memory CD4 T lymphocyte><memory T lymphocyte><microbial><mortality><novel><p50><pMHC><pathogen><pathway><programs><receptor><renal><response><secondary lymph organ><secondary lymphatic organ><secondary lymphoid organ><self-reactive T cell><sensor><social role><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment><terminally differentiated effector memory (TEM) T cells><terminally differentiated effector memory T cells><thymus derived lymphocyte><transcriptional profile><transcriptional signature><transmission process><trial regimen><trial treatment>
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Laura Pasqualucci

COLUMBIA UNIVERSITY HEALTH SCIENCES, NEW YORK, NY

Good lead · 52/100
Likely hiring
Solid budget
Active award
$475,089
FY 2026

Project Title

Role of CREBBP missense mutations in lymphomagenesis

Grant Number:

5R01CA260176-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/1/2022

End Date:

12/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

RESEARCH SUMMARY Non-Hodgkin lymphomas are the 5th leading cause of cancer in the United States. Among them, diffuse large B-cell lymphoma (DLBCL) and follicular lymphoma (FL) represent the two most common forms, together accounting for over 60% of diagnoses. Despite remarkable advances in the trea...

Research Terms

<ATAC sequencing><ATAC-seq><ATACseq><Accounting><Acetylation><Acetyltransferase><Affect><Alleles><Allelomorphs><Antigen Presentation Pathway><Antigen Processing and Presentation><Antigen-Presenting Cells><Assay><Assay for Transposase-Accessible Chromatin using sequencing><B blood cells><B cell><B cell lymphoma 2><B cell receptor><B cells><B lymphoma><B-Cell Antigen Receptor><B-Cell CLL/Lymphoma 2 Gene><B-Cell Lymphomas><B-Cells><B-Lymphocytes><B-cell><B-cell lymphoma/leukemia-2><BCL2><BCL2 gene><Bcl-2><Bioassay><Biological Assay><Biological Markers><Biology><Blood Plasma Cell><Bp50><Brill-Symmers Disease><CBP gene><CBP protein><CD40><CDW40><CREB-binding protein><CREBBP><CREBBP gene><Cancer Cause><Cancer Etiology><Cancers><Cell Body><Cell Communication and Signaling><Cell Isolation><Cell Segregation><Cell Separation><Cell Separation Technology><Cell Signaling><Cells><ChIP Sequencing><ChIP-seq><ChIPseq><Chromatin><Clinical><Complex><Coupled><DLBCL><DNA Alteration><DNA Sequence Alteration><DNA mutation><Data><Dependence><Development><Diagnosis><Diagnostic><Diffuse Large B-Cell Lymphoma><Disease><Disease remission><Disorder><Enhancers><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Event><Evolution><Expression Signature><Fluorescence Light Microscopy><Fluorescence Microscopy><Follicle Center Lymphoma><Follicular Lymphoma><Follicular Non-Hodgkin's Lymphoma><Frequencies><Gene Alteration><Gene Expression Profile><Gene Modified><Gene Mutation><Gene Transcription><Genetic><Genetic Alteration><Genetic Change><Genetic Transcription><Genetic defect><Genetic mutation><Germinal Center><Germinoblastic Sarcoma><Germinoblastoma><Giant Follicular Lymphoma><Goals><Human><Incidence><Indolent><Induced DNA Alteration><Induced Mutation><Induced Sequence Alteration><Inferior><Intracellular Communication and Signaling><KI mice><KO mice><Knock-in Mouse><Knock-out><Knock-out Mice><Knockout><Knockout Mice><Lesion><Link><Lymphoma><Lymphomagenesis><MGC9013><Maintenance><Malignant><Malignant - descriptor><Malignant Lymphoma><Malignant Neoplasms><Malignant Tumor><Malignant lymphoid neoplasm><Mass Photometry/Spectrum Analysis><Mass Spectrometry><Mass Spectroscopy><Mass Spectrum><Mass Spectrum Analyses><Mass Spectrum Analysis><Mediating><Memory B Cell><Memory B-Lymphocyte><Mice><Mice Mammals><Missense Mutation><Modeling><Modern Man><Modification><Molecular><Mouse Strains><Murine><Mus><Mutate><Mutation><Nature><Neoplastic Cell Transformation><Nodular Lymphoma><Non-Hodgkin's Lymphoma><Non-Malignant><Nonhodgkins Lymphoma><Null Mouse><Oncogenic><Outcome><Outcome Study><Pathogenesis><Patients><Pattern><Phenotype><Phylogenetic Analysis><Phylogenetics><Plasma Cells><Plasmacytes><Progenitor Cells><Proteins><RNA Decay><RNA Expression><RNA Seq><RNA sequencing><RNAseq><Recurrence><Recurrent><Relapse><Remission><Reporting><Research><Research Proposals><Reticulolymphosarcoma><Role><Sampling><Sequence Alteration><Signal Transduction><Signal Transduction Systems><Signaling><Somatic Mutation><Structure><Structure of germinal center of lymph node><TNFRSF5><TNFRSF5 gene><Therapeutic><Therapeutic Intervention><Transcription><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><Tumor Suppressor Proteins><United States><Validation><Work><accessory cell><assay for transposase accessible chromatin followed by sequencing><assay for transposase accessible chromatin seq><assay for transposase accessible chromatin sequencing><assay for transposase-accessible chromatin with sequencing><bcl-2 Genes><bio-markers><biologic marker><biological signal transduction><biomarker><ced9 homolog><cell sorting><chromatin immunoprecipitation coupled with sequencing><chromatin immunoprecipitation followed by sequencing><chromatin immunoprecipitation with sequencing><chromatin immunoprecipitation-seq><chromatin immunoprecipitation-sequencing><conventional therapy><conventional treatment><developmental><dosage><epigenetically><founder mutation><gene defect><gene expression pattern><gene expression signature><gene modification><genetically modified><genome mutation><genomic alteration><immune microenvironment><immunosuppressive microenvironment><immunosuppressive tumor microenvironment><improved><in vivo><insight><intervention therapy><knockin mice><large cell Diffuse non-Hodgkin's lymphoma><lymphoid cancers><lymphoid malignancy><malignancy><microscope imaging><microscopic imaging><microscopy imaging><missense single nucleotide polymorphism><missense single nucleotide variant><missense variant><mortality><mouse model><murine model><mutant><mutant allele><neoplasm/cancer><neoplastic><neoplastic transformation><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><non-Hodgkins disease><nonmalignant><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><p50><patient population><plasmocyte><precursor cell><programs><protein expression><recruit><response><scRNA sequencing><scRNA-seq><single cell RNA-seq><single cell RNAseq><single cell analysis><single cell expression profiling><single cell transcriptomic profiling><single-cell RNA sequencing><social role><somatic variant><stem cells><synergism><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment><therapeutic target><transcriptional profile><transcriptional signature><transcriptome sequencing><transcriptomic sequencing><tumor><tumor immune microenvironment><tumor suppressor><tumor-immune system interactions><validations>
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Saurabh Chattopadhyay

UNIVERSITY OF KENTUCKY, LEXINGTON, KY

Good lead · 52/100
Likely hiring
Solid budget
Active award
$420,465
FY 2026

Project Title

Anti-inflammatory functions for non-transcriptional IRF3

Grant Number:

5R01AI155545-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/8/2021

End Date:

1/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

Project Summary/Abstract The innate immune response is the first line of defense against microbial infection. Virus infection causes rapid induction of interferon (IFN) and IFN-induced genes, which are critical for antiviral defense. IFN regulatory factor 3 (IRF3), expressed ubiquitously, is the key...

Research Terms

<(TNF)-α><3-D structure><3-dimensional structure><3D structure><Address><Alcoholic><Alveolar Macrophages><Anti-Inflammatories><Anti-Inflammatory Agents><Anti-inflammatory><Anti-viral Response><Apoptosis><Apoptosis Pathway><Apoptotic><Basal Transcription Factor><Basal transcription factor genes><Binding><Biochemical><Boozer><Bp50><CD40><CDW40><Cachectin><Cell Body><Cells><Cytosol><Dependent drinker><Dimerization><Engineering><Epithelial Cells><Exhibits><Gene Expression><Gene Transcription><General Transcription Factor Gene><General Transcription Factors><Genes><Genetic Transcription><Goals><Grippe><Hemagglutinating Virus of Japan><Human><IFN><IFN-regulatory factor 3><IRF-3 protein><IRF3><IRF3 gene><Immune response><Immunomodulation><In Vitro><Infection><Inflammation><Inflammatory><Inflammatory Response><Influenza><Innate Immune Response><Innate Immunity><Interferon Regulatory Factor 3><Interferons><Investigators><KI mice><KO mice><Knock-in Mouse><Knock-out Mice><Knockout Mice><Knowledge><Location><LoxP-flanked allele><Lung><Lung Respiratory System><MGC9013><Macrophage><Macrophage-Derived TNF><Maps><Measures><Mediating><Mice><Mice Mammals><Microscopic><Modeling><Modern Man><Molecular><Molecular Interaction><Monocyte-Derived TNF><Murine><Mus><Mφ><NAFLD><Native Immunity><Natural Immunity><Non-Specific Immunity><Nonspecific Immunity><Nuclear Translocation><Null Mouse><Pathogenesis><Pathway interactions><Phosphorylation><Physiologic><Physiological><Predisposition><Programmed Cell Death><Property><Protein Dimerization><Protein Phosphorylation><Proteins><Pulmonary Macrophages><RNA Expression><Repression><Research><Research Personnel><Researchers><Respiratory Epithelium><Role><Sendai virus><Stimulus><Structure of respiratory epithelium><Susceptibility><TNF><TNF A><TNF Alpha><TNF gene><TNF-α><TNFA><TNFRSF5><TNFRSF5 gene><TNFα><Testing><Therapeutic><Transcription><Transcription Factor Proto-Oncogene><Transcription factor genes><Tumor Necrosis Factor><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><Tumor Necrosis Factor-alpha><Ubiquitilation><Ubiquitination><Ubiquitinoylation><Viral><Viral Activity><Viral Diseases><Viral Function><Viral Genes><Viral Pathogenesis><Viral Physiology><Virus><Virus Diseases><airway epithelium><cell type><conditional knock-out><conditional knockout><design><designing><disease model><disorder model><domain mapping><fatty liver disease><floxed><floxed allele><gene induction><genetic approach><genetic strategy><host response><immune modulation><immune regulation><immune system response><immunologic reactivity control><immunomodulatory><immunoregulation><immunoregulatory><immunoresponse><in vivo><in vivo Model><induction of genes><innovate><innovation><innovative><knockin mice><microbial><mouse model><murine model><mutant><non-alcohol fatty liver disease><non-alcoholic fatty liver disease><non-alcoholic liver disease><nonalcoholic fatty liver disease><novel><p50><p65><pathway><prevent><preventing><problem drinker><respiratory infection virus><respiratory tract epithelium><respiratory virus><response><social role><three dimensional structure><transcription factor><ubiquination><ubiquitin conjugation><viral infection><virus infection><virus pathogenesis><virus-induced disease>
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Pingwei Li

TEXAS A&M AGRILIFE RESEARCH, College Station, TX

Good lead · 52/100
Likely hiring
Solid budget
Active award
$373,814
FY 2026

Project Title

Molecular basis of viral DNA sensing through the cGAS-STING pathway

Grant Number:

5R01AI145287-07

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/20/2019

End Date:

12/31/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

The Molecular Basis of Viral DNA Sensing through the cGAS-STING Pathway The innate immune response is the first line of defense against bacterial or viral infections. Nucleic acids from the pathogens serve as danger signals to the host and induce potent innate immune responses. The cGAS- STING pathw...

Research Terms

<ABC Transport Protein><ABC Transporter Protein><ABC Transporters><ABC29><ABCC><ABCC1><ABCC1 gene><ATP-Binding Cassette Transporters><Agonist><Antitumor Response><Assay><Autoimmune Diseases><Autophagocytosis><Bacterial Infections><Basal Transcription Factor><Basal transcription factor genes><Binding><Binding Site Domain><Bioassay><Biological Assay><Bp50><C-terminal><CD40><CDW40><Cancers><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><Complex><Core Particle><Cryo-electron Microscopy><Cryoelectron Microscopy><Cyclic GMP><DNA><DNA Binding><DNA Binding Interaction><DNA bound><Deoxyribonucleic Acid><Dimerization><Double-Stranded DNA><Electron Cryomicroscopy><Endogenous Interferon Beta><Event><FLJ11330><Family><Fibroblast Interferon><Foundations><GS-X><Gene Transcription><General Transcription Factor Gene><General Transcription Factors><Genes><Genetic Transcription><Goals><Guanosine Cyclic Monophosphate><Health><Human><IFN><IFN-regulatory factor 3><IFN-β><IFNb><IRF-3 protein><IRF3><IRF3 gene><Immune response><Immunoglobulin Enhancer-Binding Protein><Inflammatory><Innate Immune Response><Innate Immunity><Interferon Regulatory Factor 3><Interferon Type I><Interferon-β><Interferons><Intracellular Communication and Signaling><Intracellular Second Messenger><Invaded><Investigation><Kinases><Length><Ligand Binding><Ligand Binding Domain><MGC9013><MK-0571><MK-571><MRP1><Malignant Neoplasms><Malignant Tumor><Mediating><Modern Man><Molecular><Molecular Interaction><NF-Kb-Activating Kinase Gene><NF-kB><NF-kappa B><NF-kappaB><NFKB><Native Immunity><Natural Immunity><Natural Interferon Beta><Natural human interferon beta><Non-Specific Immunity><Nonspecific Immunity><Nuclear Factor kappa B><Nuclear Transcription Factor NF-kB><Nucleic Acids><Nucleosome Core><Nucleosome Core Particle><Nucleosomes><Pathway interactions><Pattern><Pattern recognition receptor><Peptides><Phosphorylation><Phosphotransferase Gene><Phosphotransferases><Play><Protein Dimerization><Protein Phosphorylation><RNA Expression><Reagent><Research><Rest><Role><Second Messenger Systems><Second Messengers><Signal Transduction><Signal Transduction Systems><Signaling><Stimulator of Interferon Genes><Structure><T2K><TBK1><TBK1 gene><TNFRSF5><TNFRSF5 gene><Tail><Transcription><Transcription Activator><Transcription Coactivator><Transcription Factor Coactivator><Transcription Factor NF-kB><Transcription Factor Proto-Oncogene><Transcription Initiation><Transcription factor genes><Transcriptional Activator/Coactivator><Transphosphorylases><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><Ubiquitilation><Ubiquitination><Ubiquitinoylation><Viral><Viral Diseases><Virus><Virus Diseases><anti-tumor response><autoimmune condition><autoimmune disorder><autoimmunity disease><autophagy><bacteria infection><bacterial disease><base><bases><biological signal transduction><cGAMP STING><cGAMP-STING><cGAMP/STING><cGAS/STING><cGMP><combat><cryo-EM><cryoEM><cryogenic electron microscopy><cyclic GMP-AMP synthase/STING><cytokine><drug development><ds-DNA><dsDNA><host response><human disease><immune system response><immunoresponse><innate immune mechanisms><innate immune pathways><innovate><innovation><innovative><insight><kappa B Enhancer Binding Protein><malignancy><neoplasm/cancer><new approaches><novel approaches><novel strategies><novel strategy><nuclear factor kappa beta><p50><p65><pathogen><pathogenic virus><pathway><promoter><promotor><recruit><response><signal transduction second messengers><small molecule><social role><synergism><transcription factor><ubiquination><ubiquitin conjugation><viral DNA><viral infection><viral pathogen><virus DNA><virus infection><virus pathogen><virus-induced disease>
View Full Project Details on NIH Reporter
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MICHAEL F MILES

VIRGINIA COMMONWEALTH UNIVERSITY, RICHMOND, VA

Good lead · 50/100
Training-friendly
Solid budget
Recent
Active award
$305,327
FY 2026

Project Title

Cross-Species Multidisciplinary Training in Alcohol Research

Grant Number:

5T32AA029975-04

Activity Code:

T32

Mechanism:

Training, Institutional

Agency:

NIH

Start Date:

4/1/2023

End Date:

3/31/2028

Why this may be worth a closer look

  • • Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

This revised application proposes a new T32 Institutional National Research Service Award with five years of support to fund Cross-Species Multidisciplinary Training in Alcohol Research, comprising four pre-doctoral and two postdoctoral trainees. Virginia Commonwealth University (VCU) has a history ...

Research Terms

<Training><alcohol related research><alcohol research><ethanol research><multidisciplinary>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Brien P Riley

VIRGINIA COMMONWEALTH UNIVERSITY, RICHMOND, VA

Good lead · 50/100
Training-friendly
Solid budget
Recent
Active award
$305,327
FY 2026

Project Title

Cross-Species Multidisciplinary Training in Alcohol Research

Grant Number:

5T32AA029975-04

Activity Code:

T32

Mechanism:

Training, Institutional

Agency:

NIH

Start Date:

4/1/2023

End Date:

3/31/2028

Why this may be worth a closer look

  • • Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

This revised application proposes a new T32 Institutional National Research Service Award with five years of support to fund Cross-Species Multidisciplinary Training in Alcohol Research, comprising four pre-doctoral and two postdoctoral trainees. Virginia Commonwealth University (VCU) has a history ...

Research Terms

<Training><alcohol related research><alcohol research><ethanol research><multidisciplinary>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Chang-Yu Alex Chen

MASSACHUSETTS GENERAL HOSPITAL, BOSTON, MA

Good lead · 48/100
Training-friendly
Recent
Active award
Career award
$176,040
FY 2026

Project Title

The effect of aging on cDC1 function and CD8 T cell immunity in tumors

Grant Number:

5K99CA296769-02

Activity Code:

K99

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

4/1/2025

End Date:

3/31/2027

Why this may be worth a closer look

  • • Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT SUMMARY/ ABSTRACT Aging is a well-established risk factor for the development of cancer and is associated with a gradual decline in immune function. Studies have indicated that this age-related decline in immune function can hamper the effectiveness of CD8+ T cell immunity and restrict the r...

Research Terms

<Address><Advisory Committees><Affect><Age><Aging><Antigen Presentation><Antigens><Assay><Bioassay><Biological Assay><Biopsy><Blood><Blood Reticuloendothelial System><Bone Marrow><Bone Marrow Reticuloendothelial System><Bp50><CD40><CD8 Cell><CD8 T cells><CD8 lymphocyte><CD8+ T cell><CD8+ T-Lymphocyte><CD8-Positive Lymphocytes><CD8-Positive T-Lymphocytes><CD86><CD86 gene><CDW40><CRG-2><CXCL10><CXCL10 gene><CXCL9><CXCL9 gene><Cancer Control><Cancer Control Science><Cancer Patient><Cancers><Cell Body><Cell Communication><Cell Count><Cell Function><Cell Interaction><Cell Isolation><Cell Number><Cell Physiology><Cell Process><Cell Segregation><Cell Separation><Cell Separation Technology><Cell secretion><Cell-to-Cell Interaction><Cells><Cellular Function><Cellular Immune Function><Cellular Physiology><Cellular Process><Cellular Secretion><Cellular biology><Chemotactic Cytokines><Collaborations><Complement><Complement Proteins><Complex><Data><Defect><Dendritic Cells><Development><Dysfunction><Effectiveness><Elderly><Environment><Exhibits><FLK2><FLT 3 Ligand><FLT3><FLT3 gene><FLT3 ligand><FLT3L><FLT3LG><FLT3LG gene><FMS-Related Tyrosine Kinase 3 Ligand Gene><FMS-Related Tyrosine Kinase-3 Ligand><FMS-like tyrosine kinase 3><Fms-Related Tyrosine Kinase 3><Functional disorder><Goals><Homologous Chemotactic Cytokines><Human><Humig><IFI10><INP10><IP-10><Image><Immune><Immune mediated therapy><Immune response><Immunes><Immunity><Immunologically Directed Therapy><Immunology><Immunotherapy><Impairment><Injections><Intercrines><Intervention><Investigators><Knowledge><Lymph Node Reticuloendothelial System><Lymph node proper><Lymphatic nodes><MGC9013><MIG Gene><MOB-1><Malignant Melanoma><Malignant Neoplasms><Malignant Tumor><Melanoma><Melanoma Tumor><Melanoma patient><Mentors><Mentorship><Mice><Mice Mammals><Modern Man><Molecular><Monitor><Murine><Mus><Myelogenous><Myeloid><Nature><Organ><PD 1><PD-1><PD-L1 blockade><PD1><PDL1 blockade><Personalized medical approach><Phase><Physiopathology><Play><Production><Publishing><Rejuvenation><Research><Research Personnel><Researchers><Risk><Risk Factors><Role><SCYB10><SCYB9><SIS cytokines><STK-1 kinase><STK1><STK1-ligand><Sorting><Stem Cell Tyrosine Kinase 1><Stem Cell like><Subcellular Process><T cell receptor repertoire sequencing><T cell receptor sequencing><T cell response><T-Cells><T-Lymphocyte><T8 Cells><T8 Lymphocytes><TCR repertoire sequencing><TCR sequencing><TCR-seq><TCRseq><TNFRSF5><TNFRSF5 gene><Task Forces><Techniques><Testing><Therapeutic><Training><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><Tumor Promotion><Tumor growth in melanoma><Veiled Cells><Work><advanced age><advisory team><age associated><age associated decline><age associated effects><age correlated><age dependent><age dependent decline><age effect><age linked><age related><age related decline><age related effects><age specific><aged><ages><aging effect><anti-PD-L1 blockade><cancer microenvironment><career><cell biology><cell sorting><chemoattractant cytokine><chemokine><complementation><crg-10><cytokine><decline with age><developmental><draining lymph node><elderly patient><exhaust><experiment><experimental research><experimental study><experiments><fetal liver kinase-2><fetal liver kinase-3><flk2 ligand><flk2-flt3 ligand><flt3 ligand protein><gIP-10><geriatric><host response><imaging><immune function><immune system response><immune therapeutic approach><immune therapeutic interventions><immune therapeutic regimens><immune therapeutic strategy><immune therapy><immune-based therapies><immune-based treatments><immuno therapy><immunogen><immunoresponse><impact of age><improved><in vivo><individualized approach><influence of age><innovate><innovation><innovative><insight><lymph gland><lymph nodes><lymphnodes><malignancy><melanoma cancer model><melanoma model><melanoma tumor model><mouse model><multiomics><multiple omics><murine model><neoplasm/cancer><novel><older patient><p50><panomics><pathophysiology><patients suffering from melanoma><patients with melanoma><personalized approach><precision approach><prevent><preventing><progenitor capacity><progenitor cell differentiation><progenitor cell like><progenitor differentiation><progenitor-like><progenitor-like cell><programmed cell death 1><programmed cell death protein 1><programmed death 1><proliferation capability><proliferation capacity><proliferation potential><proliferative capability><proliferative capacity><proliferative potential><recruit><regional lymph node><response><senior citizen><skills><sle2><social role><spatial RNA sequencing><spatial gene expression analysis><spatial gene expression profiling><spatial resolved transcriptome sequencing><spatial transcriptome analysis><spatial transcriptome profiling><spatial transcriptome sequencing><spatial transcriptomics><spatially resolved transcriptomics><spatio transcriptomics><stem and progenitor differentiation><stem cell characteristics><stem cell differentiation><stem cell tyrosine kinase 1 ligand><stem-like><stem-like cell><stemness><systemic lupus erythematosus susceptibility 2><tailored approach><thymus derived lymphocyte><transcriptomics><tumor><tumor growth><tumor microenvironment>
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Jesus Jimenez

WASHINGTON UNIVERSITY, SAINT LOUIS, MO

Good lead · 48/100
Training-friendly
Recent
Active award
Career award
$162,705
FY 2026

Project Title

CD40 Immunotherapy Effect on the Cardiac Immune Landscape and Response to Myocardial Disease

Grant Number:

5K08HL163518-03

Activity Code:

K08

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

12/1/2023

End Date:

11/30/2028

Why this may be worth a closer look

  • • Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

Project Summary/Abstract (30 lines) Immunotherapy has revolutionized cancer treatment and is a cornerstone of standard clinical practice and ongoing clinical trials. However, some immunotherapies including immune checkpoint inhibitors (ICIs) impart adverse cardiac events ranging from arrhythmias to ...

Research Terms

<(TNF)-α><Acceleration><Address><Agonist><AngII><Angiotensin II><Antibodies><Antigen Presentation><Antigen-Presenting Cells><Arrhythmia><Assay><B blood cells><B cell><B cells><B-Cells><B-Lymphocytes><B-cell><Bioassay><Bioinformatics><Biological Assay><Body Tissues><Bp50><C-C Chemokines><CC Chemokines><CD154 Antigens><CD40><CD40 Ligand><CD40-L><CDW40><CITE sequencing><CITE-seq><CITEseq><CTLA-4 blockade><CTLA4 blockade><Cachectin><Cancer Model><Cancer Patient><Cancer Treatment><CancerModel><Cancers><Cardiac><Cardiac Arrhythmia><Cardiomyopathies><Cardiovascular><Cardiovascular Body System><Cardiovascular Diseases><Cardiovascular Organ System><Cardiovascular system><Caring><Cell Body><Cell Communication and Signaling><Cell Signaling><Cell Surface Proteins><Cells><Cellular Indexing of Transcriptomes and Epitopes by Sequencing><Characteristics><Checkpoint inhibitor><Chemokine Receptor Gene><Chemotactic Cytokines><Clinical><Clinical Trials><Competence><Data><Dendritic Cells><Development><Development Plans><Doctor of Philosophy><Eligibility><Eligibility Determination><Evaluation><Event><Fatality rate><Fellowship><Flow Cytofluorometries><Flow Cytofluorometry><Flow Cytometry><Flow Microfluorimetry><Flow Microfluorometry><Gene Expression><Genetic><Goals><Grant><HIGM1><Heart><Heart Arrhythmias><Heart Injuries><Heart Vascular><Homologous Chemotactic Cytokines><IFN-Gamma><IFN-Gamma Receptor><IFN-g><IFN-γ><IFN-γ Receptor><IFNG><IFNγ><IMD3><Immune><Immune Interferon><Immune checkpoint inhibitor><Immune mediated therapy><Immune response><Immunes><Immunologically Directed Therapy><Immunology><Immunotherapy><Impairment><Infiltration><Inflammation><Inflammatory><Inflammatory Response><Infusion><Infusion procedures><Injections><Injury><Integral Membrane Protein><Intercrines><Interferon Gamma><Interferon Gamma Receptor Complex><Interferon Type II><Internal Medicine><Intracellular Communication and Signaling><Intrinsic Membrane Protein><KO mice><Knock-out Mice><Knockout Mice><LV remodeling><Left Ventricular Remodeling><Ligands><Lineage Tracing><MGC9013><Macrophage><Macrophage Activation><Macrophage-Derived TNF><Malignant Neoplasm Therapy><Malignant Neoplasm Treatment><Malignant Neoplasms><Malignant Tumor><Manuscripts><Mediating><Mediator><Mentors><Mentorship><Mice><Mice Mammals><Monocyte-Derived TNF><Murine><Mus><Myocardial><Myocardial Diseases><Myocardial Disorder><Myocardiopathies><Myocarditis><Mφ><Null Mouse><Oncology><Oncology Cancer><Outcome><PD 1><PD-1><PD-1 inhibitors><PD-L1 blockade><PD1><PD1 inhibitors><PDL1 blockade><Patients><Ph.D.><PhD><Phenotype><Phenylephrine><Physicians><Postdoc><Postdoctoral Fellow><Preparation><Principal Investigator><Production><Protocol Screening><Receptor Protein><Research><Research Associate><Role><SIS cytokines><Scientist><Shapes><Signal Transduction><Signal Transduction Systems><Signaling><Single cell seq><T cell response><T memory cell><T-B Cell Activating Molecule><T-Cell Activation><T-Cell Subsets><T-Cell gp39 Antigen><T-Cells><T-Lymphocyte><T-Lymphocyte Subsets><TNF><TNF A><TNF Alpha><TNF gene><TNF-Related Activation Protein><TNF-α><TNFA><TNFRSF5><TNFRSF5 gene><TNFα><Technical Expertise><Testing><Tissues><Training><Transmembrane Protein><Transmembrane Protein Gene><Tumor Necrosis Factor><Tumor Necrosis Factor Ligand Superfamily Member 5><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><Tumor Necrosis Factor-alpha><Veiled Cells><Writing><accessory cell><activate T cells><anti programmed cell death protein 1 inhibitor><anti-PD-1 inhibitors><anti-PD-L1 blockade><anti-PD1 inhibitors><anti-cancer immunotherapy><anti-cancer therapy><anticancer immunotherapy><autoimmune check point><autoimmune checkpoint><autoimmunity check point><autoimmunity checkpoint><beta-Chemokines><biological signal transduction><cancer immunotherapy><cancer therapy><cancer-directed therapy><cardiac inflammation><cardiac injury><cardiovascular disorder><career development><cell lineage analysis><cell lineage mapping><cell lineage tracing><cell lineage tracking><cellular indexing of transcriptomes and epitopes by single cell sequencing><cellular lineage mapping><cellular lineage tracking><chemoattractant cytokine><chemokine><chemokine receptor><circulatory system><clinical practice><clinical training><conditional knock-out><conditional knockout><cytokine><cytotoxic><developmental><flow cytophotometry><host response><immune check point><immune check point inhibitor><immune checkpoint><immune system response><immune therapeutic approach><immune therapeutic interventions><immune therapeutic regimens><immune therapeutic strategy><immune therapy><immune-based cancer therapies><immune-based therapies><immune-based treatments><immunecheckpoint><immuno therapy><immunoresponse><immunotherapy for cancer><immunotherapy of cancer><improved><infusions><inhibitor drug><inhibitor therapeutic><inhibitor therapy><injuries><injury to the myocardium><innovate><innovation><innovative><insight><lFN-Gamma><left ventricle remodeling><malignancy><member><memory T lymphocyte><myocardial injury><myocardium disease><myocardium disorder><neoplasm/cancer><p50><post-doc><post-doctoral><post-doctoral trainee><preparations><programmed cell death 1><programmed cell death protein 1><programmed death 1><programs><protein expression><receptor><recruit><research associates><response><single cell next generation sequencing><single cell sequencing><skills><sle2><social role><systemic lupus erythematosus susceptibility 2><targeted cancer therapy><technical skills><thymus derived lymphocyte><tumor><β-Chemokines>
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Shannon Fuller

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

Good lead · 48/100
Training-friendly
Very recent
Active award
$50,114
FY 2026

Project Title

A Mixed Methods Exploration of Community Health Workers’ Integration into Clinical Settings

Grant Number:

5F31MD019527-02

Activity Code:

F31

Mechanism:

Training, Individual

Agency:

NIH

Start Date:

12/1/2024

End Date:

11/30/2026

Why this may be worth a closer look

  • • Activity code is useful for trainees, fellows, or mentored roles.
  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Community health workers (CHWs) are lay health workers who are part of or closely affiliated with the communities that they serve. A large body of evidence demonstrates that CHW-delivered interventions improve health outcomes and reduce disparities across a range of conditions. CHWs work in various ...

Research Terms

<Address><Area><Behavior><Behavioral Sciences><Caring><Characteristics><Client><Clinic><Clinical><Clinical Services><Collection><Communities><Community Health Aides><Community Surveys><Complement><Complement Proteins><Consensus><Consolidated Framework for Implementation Research><Consolidated Framework for Implementation Science><Consolidated Framework for Implementing Change><Data><Data Analyses><Data Analysis><Data Collection><Decrease disparity><Decrease health disparities><Dedications><Disparities><Disparity><Doctor of Philosophy><Education><Educational aspects><Effectiveness><Ethnography><Evidence based intervention><Fellowship><Fostering><Goals><Grant><Health><Health Care Facility><Health Care Providers><Health Care Team><Health Disparities Research><Health Facilities><Health Instruction><Health Personnel><Health Services Evaluation><Health Services Research><Health Tutoring><Health disparities related research><Health disparity mitigation><Health disparity reduction><Health education><Individual><Institution><Intervention><Interview><Investigators><Job Location><Job Place><Job Setting><Job Site><Literature><Lower disparity><Lower health disparities><Maryland><Measures><Medical><Medical Care Research><Medical Care Team><Mentors><Mentorship><Methodology><Methods><Mitigate health disparities><Modeling><NCMHD><NIMHD><National Center on Minority Health and Health Disparities><National Institute of Minority Health and Health Disparities><National Institute on Minority Health and Health Disparities><Outcome><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Pattern><Ph.D.><PhD><Play><Population><Position><Positioning Attribute><Process><Public Health Schools><QOC><QOL><Quality of Care><Quality of life><R-Series Research Projects><R01 Mechanism><R01 Program><Reduce health disparities><Research><Research Activity><Research Grants><Research Methodology><Research Methods><Research Personnel><Research Project Grants><Research Projects><Research Resources><Researchers><Resources><Risk Factors><Role><Social Sciences><Stress><Supervision><Survey Instrument><Surveys><Theoretical Domains framework><Training><Training Activity><Translations><United States><Work><Work Location><Work Place><Work-Site><Workplace><Worksite><Writing><access to health care><accessibility of health care><accessibility to health care><burn-out><burnout><cardiometabolic><cardiometabolism><care facilities><career><clinical care><community based organizations><community based participatory research><community engaged participatory research><community engaged research><community health worker><community led research><community organizations><community participatory research><community partnered participatory research><community partnered research><community-engaged study><community-partnered study><complementation><context for implementation><cultural competence><culturally competent><data interpretation><design><designing><disenfranchised group><disenfranchised individual><disenfranchised people><disenfranchised population><disparity in health><disparity reduction><dissemination strategy><ethnographic><ethnographic method><experience><health care access><health care availability><health care personnel><health care service><health care service access><health care service availability><health care settings><health care worker><health disparities science><health disparity><health outcome disparity><health outcome inequality><health outcome inequity><health provider><health staff><health workers><health workforce><healthcare employees><healthcare staff><healthcare workforce><implementation context><implementation determinants><implementation factors><implementation framework><implementation research framework><implementation science><implementation science framework><improved><inequitable health outcome><insight><integrated care><integrated health care><integrated model of care><interest><marginalization><medical care providers><medical personnel><meeting><meetings><member><mitigate disparity><participant observation><participatory action research><patient navigation><patient oriented outcomes><perceived stress><perception of stress><programs><recruit><reduce disparity><reduction in disparity><research and methods><research study><self-reported stress><services research><skills><social><social health determinants><social role><socially disenfranchised><stress perception><theories><training module><translation><treatment provider><unequal health outcome><work setting>
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Marcus E. Peter

NORTHWESTERN UNIVERSITY, CHICAGO, IL

Good lead · 46/100
Likely hiring
Solid budget
Active award
$477,698
FY 2025

Project Title

Novel immune suppressive activities of Fas/CD95 in triple negative breast cancer

Grant Number:

5R01CA267815-04

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

7/7/2022

End Date:

6/30/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

Summary Among women, breast cancer (BC) is the most common malignancy, and the second leading cause of cancer death. Patients with basal/triple negative BC (TNBC) have the poorest clinical outcome with no targeted therapies available when compared to other molecular subtypes. Fas/CD95 is a well char...

Research Terms

<APO-1><APO-1 Antigen><APO-1 Cell Surface Antigen><Antitumor Response><Apoptosis Antigen 1><Assay><Binding><Binding Proteins><Bioassay><Biochemical><Biological Assay><Body Tissues><Bp50><Breast Cancer><Breast Cancer Cell><C-terminal><CD40><CD95><CD95 Antigens><CD95 molecule><CDW40><Cancer Cause><Cancer Etiology><Cancer Treatment><Cancers><Cell Body><Cell Communication and Signaling><Cell Signaling><Cells><Cessation of life><Checkpoint inhibitor><Clinic><Clinical><Complement><Complement Proteins><Complex><Cytotoxic cell><DNA Recombination><Data><Death><Equilibrium><FASTM><Fas Signaling Pathway><GEM model><GEMM model><Gene Transcription><General Prognostic Factor><Generalized Growth><Genetic Recombination><Genetic Transcription><Genetically Engineered Mouse><Goals><Growth><Immune><Immune Cell Activation><Immune checkpoint inhibitor><Immune mediated therapy><Immunes><Immunocompetent><Immunoglobulin Enhancer-Binding Protein><Immunologically Directed Therapy><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><Immunotherapy><Implant><In Vitro><Induction of Apoptosis><Infiltration><Inflammatory><Intracellular Communication and Signaling><K Cells><K lymphocyte><KO mice><Killer Cells><Knock-out><Knock-out Mice><Knockout><Knockout Mice><Knowledge><Ligand Binding Protein><Ligand Binding Protein Gene><Ligands><Lymphocytic Infiltrate><MGC9013><Malignant Breast Neoplasm><Malignant Cell><Malignant Neoplasm Therapy><Malignant Neoplasm Treatment><Malignant Neoplasms><Malignant Tumor><Mediating><Metastasis><Metastasize><Metastatic Lesion><Metastatic Mass><Metastatic Neoplasm><Metastatic Tumor><Mice><Mice Mammals><Modeling><Molecular><Molecular Interaction><Mouse Cell Line><Mouse Strains><Murine><Mus><Myeloid-derived suppressor cells><NF-Kappa B p65><NF-kB><NF-kB p65 Subunit><NF-kappa B><NF-kappa B p65 subunit><NF-kappa Bp65><NF-kappaB><NF-kappaB 65-kDa><NF-kappaB(p65)><NFKB><NK Cells><NMR Spectrometer><NMR Spectroscopy><Natural Killer Cells><Nature><Neoplasm Metastasis><Nuclear Factor Kappa-B Subunit 3><Nuclear Factor NF-Kappa-B p65 Subunit><Nuclear Factor kappa B><Nuclear Factor of Kappa Light Chain Gene Enhancer in B Cells 3><Nuclear Transcription Factor NF-kB><Null Mouse><Outcome><Patients><Production><Prognosis><Prognostic Factor><Prognostic/Survival Factor><Protein Binding><Public Health><RNA Expression><Receptor Protein><Recombination><Role><Secondary Neoplasm><Secondary Tumor><Signal Transduction><Signal Transduction Systems><Signaling><TNBC><TNFRSF5><TNFRSF5 gene><TNFRSF6><TNFRSF6 Receptor><TNFRSF6 gene><Testing><Tissue Growth><Tissues><Transcription><Transcription Factor NF-kB><Transcription Factor NFKB3><Transcription Factor p65><Tumor Cell><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><Tumor Necrosis Factor Receptor Superfamily, Member 6><Tumor Promotion><Ubiquitin Ligase Component Gene><Ubiquitin Ligase Gene><V-REL Avian Reticuloendotheliosis Viral Oncogene Homolog A><Woman><Work><anti-cancer therapy><anti-tumor response><balance><balance function><biological signal transduction><bound protein><breast tumor cell><cancer cell><cancer metastasis><cancer microenvironment><cancer sub-types><cancer subtypes><cancer therapy><cancer-directed therapy><chemical library><complementation><crosslink><cytokine><derepression><design><designing><expression subtypes><fas Antigens><fas Receptors><genetically engineered mouse model><genetically engineered murine model><immune activation><immune check point><immune check point inhibitor><immune checkpoint><immune competent><immune suppression><immune suppressive activity><immune suppressive function><immune therapeutic approach><immune therapeutic interventions><immune therapeutic regimens><immune therapeutic strategy><immune therapy><immune-based therapies><immune-based treatments><immunecheckpoint><immuno therapy><immunosuppressive activity><immunosuppressive function><immunosuppressive myeloid cells><immunosuppressive response><improved><in vivo><inhibitor><kappa B Enhancer Binding Protein><malignancy><malignant breast tumor><molecular sub-types><molecular subsets><molecular subtypes><mouse model><murine model><myeloid suppressor cells><myeloid-derived suppressive cells><neoplasm/cancer><neoplastic cell><novel><nuclear factor kappa beta><nuclear magnetic resonance spectroscopy><ontogeny><p50><p65><peptide mimetic><peptide mimic><peptidomimetics><permissiveness><programs><protein complex><receptor><recruit><scRNA sequencing><scRNA-seq><screening><screenings><single cell RNA-seq><single cell RNAseq><single cell expression profiling><single cell transcriptomic profiling><single-cell RNA sequencing><small molecule libraries><social role><suppressive myeloid cells><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment><triple-negative breast cancer><triple-negative invasive breast carcinoma><tumor><tumor cell metastasis><tumor growth><tumor microenvironment><ubiquitin ligase>
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Kenneth M Murphy

WASHINGTON UNIVERSITY, SAINT LOUIS, MO

Good lead · 46/100
Likely hiring
Solid budget
Active award
$463,700
FY 2025

Project Title

Understanding the Mechanisms of DC Licensing in CD8 T Cell Priming

Grant Number:

5R01CA248919-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

6/1/2021

End Date:

5/31/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

ABSTRACT Effective responses to viruses, intracellular pathogens and tumors rely on the successful expansion and arming of cytolytic CD8 T cells from a naïve and quiescent T cell repertoire. This process, called CD8 T cell priming, is dependent on a specialized antigen-presenting cell known as conve...

Research Terms

<Antigen Presentation><Antigen-Presenting Cells><Antigens><Antitumor Response><Basal Transcription Factor><Basal transcription factor genes><Bp50><CD154><CD154 Antigens><CD4 Cells><CD4 Positive T Lymphocytes><CD4 T cells><CD4 helper T cell><CD4 lymphocyte><CD4+ T-Lymphocyte><CD4-Positive Lymphocytes><CD40><CD40 Ligand><CD40-L><CD40L><CD40LG><CD8><CD8 Cell><CD8 T cells><CD8 lymphocyte><CD8+ T cell><CD8+ T-Lymphocyte><CD8-Positive Lymphocytes><CD8-Positive T-Lymphocytes><CD8B><CD8B1><CD8B1 gene><CDW40><Cardiolipins><Cell Body><Cell Communication><Cell Communication and Signaling><Cell Interaction><Cell Signaling><Cell-to-Cell Interaction><Cells><Cross Presentation><Data><Dendritic Cells><Development><Enhancers><Exclusion><Gamma-delta T cells><Gene Deletion><General Transcription Factor Gene><General Transcription Factors><Genes><HIGM1><Helper Cells><Helper T-Cells><Helper T-Lymphocytes><Helper-Inducer T-Cells><Helper-Inducer T-Lymphocyte><IMD3><Individual><Inducer Cells><Inducer T-Lymphocytes><Intracellular Communication and Signaling><Knowledge><LYT3><Licensing><Ligands><Lineage Tracing><Lipids><MGC9013><MHC Receptor><Major Histocompatibility Complex Receptor><Methods><Mice><Mice Mammals><Modeling><Murine><Mus><Nature><Pathway interactions><Process><Publishing><Role><Signal Induction><Signal Transduction><Signal Transduction Systems><Signaling><Source><T cell response><T-B Cell Activating Molecule><T-Cell Antigen Receptors><T-Cell Receptor><T-Cell gp39 Antigen><T-Cells><T-Lymphocyte><T4 Cells><T4 Lymphocytes><T8 Cells><T8 Lymphocytes><TNF-Related Activation Protein><TNFRSF5><TNFRSF5 gene><TNFSF5><TNFSF5 gene><TRAP Gene><Testing><Time><Transcription Factor Proto-Oncogene><Transcription factor genes><Tumor Immunity><Tumor Necrosis Factor Ligand Superfamily Member 5><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><Tumor Promotion><Tumor-Derived><Veiled Cells><Virus><Work><accessory cell><anti-tumor immunity><anti-tumor response><antitumor immunity><arm><biological signal transduction><cancer immunity><cell lineage analysis><cell lineage mapping><cell lineage tracing><cell lineage tracking><cell type><cellular lineage mapping><cellular lineage tracking><developmental><gene deletion mutation><immunogen><in vivo><neo-antigen><neo-epitopes><neoantigens><neoepitopes><new drug target><new druggable target><new pharmacotherapy target><new therapeutic target><new therapy target><novel><novel drug target><novel druggable target><novel pharmacotherapy target><novel therapeutic target><novel therapy target><p50><pathogen><pathway><programs><response><social role><thymus derived lymphocyte><transcription factor><transgene expression><tumor><γδ T cells><γδT cells>
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YOSUKE KUMAMOTO

RUTGERS BIOMEDICAL AND HEALTH SCIENCES, Newark, NJ

Good lead · 46/100
Likely hiring
Solid budget
Active award
$444,895
FY 2025

Project Title

Regulation of Th2 differentiation by skin-resident dendritic cells

Grant Number:

5R01AI132576-08

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/1/2017

End Date:

5/31/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

Project Summary T helper type 2 (Th2) cells play a crucial role in allergies, humoral immunity and host protection against parasitic infections, but our understanding of the mechanism of their differentiation remains incomplete. Upon encountering a cognate antigen presented by dendritic cells (DCs),...

Research Terms

<Address><Allergens><Allergic Disease><Allergy><Ancylostomatidae><Antigen Presentation><Antigen-Presenting Cells><Antigens><Applications Grants><Back><Bp50><Business-Friendly Atmosphere><CD25><CD40><CDW40><Cell Body><Cell Communication and Signaling><Cell Differentiation><Cell Differentiation process><Cell Signaling><Cells><Closure by Ligation><Co-Stimulator><Communicable Diseases><Core Facility><Corium><Costimulator><Cues><Cutis><Data><Dendritic Cells><Dermis><Differentation Markers><Differentiation Antigens><Differentiation Markers><Disease><Disorder><Dorsum><Edodekin Alfa><Effector Cell><Epidermal Thymocyte Activating Factor><Equipment><Esteroproteases><Event><Exposure to><Focus Groups><GeneHomolog><Goals><Grant Proposals><HDAC7><HDAC7 histone deacetylase><Helminths><Helper Cells><Helper T-Cells><Helper T-Lymphocytes><Helper-Inducer T-Cells><Helper-Inducer T-Lymphocyte><Homolog><Homologous Gene><Homologue><Hookworms><Human><Humoral Immunities><IL-12><IL-2><IL-23><IL12><IL2 Protein><IL2R><IL2RA><IL2RA gene><Immune><Immune response><Immunes><Immunity><Inducer Cells><Inducer T-Lymphocytes><Infection><Infectious Diseases><Infectious Disorder><Inflammation><Instruction><Interleukin 2><Interleukin 2 Precursor><Interleukin II><Interleukin-12><Interleukin-2><Interleukine 2><Interleukine 2 Precursor><Interleukine II><Intracellular Communication and Signaling><Kinetics><Ligation><Lung><Lung Respiratory System><Lymphocyte Mitogenic Factor><MGC9013><Marker Antigens><Mediating><Mitogenic Factor><Modeling><Modern Man><Molecular><NKSF><Natural Killer Cell Stimulatory Factor><Nippostrongylus><Organ><Papain><Parasitic Worms><Parasitic infection><Peptidases><Peptide Hydrolases><Peripheral><Phenotype><Play><Protease Gene><Proteases><Proteinases><Proteolytic Enzymes><Regulation><Role><Scanning><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><Skin><Supporting Cell><T cell growth factor><T-Cell Growth Factor><T-Cell Stimulating Factor><TCGFR><TNFRSF5><TNFRSF5 gene><Testing><Th-2 Cell><Th2 Cells><Therapeutic><Thymocyte Stimulating Factor><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><Type 2 Helper Cell><Upregulation><Vaccines><Veiled Cells><accessory cell><adaptive immunity><antibody-based immunity><biological signal transduction><business-friendly environment><cell type><cellular differentiation><collaborative atmosphere><collaborative environment><develop a vaccine><develop vaccines><development of a vaccine><experiment><experimental research><experimental study><experiments><gene manipulation><genetic manipulation><genetically manipulate><genetically perturb><helminth infection><helminthic infection><host response><immune system response><immunogen><immunopathology><immunoresponse><imprint><improved><in vivo><infected with helminth><infected with parasites><interactive atmosphere><interactive environment><interdisciplinary atmosphere><interdisciplinary environment><interleukin-23><mHDAC7><mouse model><murine model><novel><p50><parasite infection><pathogen><peer-group atmosphere><peer-group environment><response><selective expression><selectively expressed><skin allergy><skin hypersensitivity><social role><vaccine development>
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SCOTT H KAUFMANN

MAYO CLINIC ROCHESTER, ROCHESTER, MN

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$210,627
FY 2025

Project Title

Use of microfluidic tumor cultures to enable clinical trials of therapies for ovarian cancer

Grant Number:

3P50CA136393-14S1

Activity Code:

P50

Mechanism:

Research Centers

Agency:

NIH

Start Date:

7/1/2009

End Date:

8/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

ABSTRACT With an estimated 20,000 new cases and 13,000 deaths in 2024, ovarian cancers (OCs) remain the deadliest gynecological malignancy. Despite the heterogeneity of this group of cancers in terms of histology, possible cell of origin, and genomic alterations, OCs are almost universally treated w...

Research Terms

<3-D><3-Dimensional><3D><Acceleration><Adjuvant><Adjuvant Chemotherapy><Adjuvant Drug Therapy><Advanced Development><After Care><After-Treatment><Aftercare><Animal Model><Animal Models and Related Studies><Basic Research><Basic Science><Bioinformatics><Biometrics><Biometry><Biostatistics><CAR NK><CBDCA><CDDP><CIS Gene><CIS protein><CIS-1 Gene><CIS-1 Protein><CISH Protein><CISH gene><Cancer Patient><Cancer Relapse><Cancer Treatment><Cancer cell line><Cancers><Carboplatin><Carboplatino><Cell Body><Cell Therapy><Cells><Cessation of life><Cis-diammine-dichloroplatinum><Cis-diamminedichloridoplatinum><Cis-diamminedichloro Platinum (II)><Cis-dichloroammine Platinum (II)><Cis-platinous Diamine Dichloride><Cis-platinum II><Cis-platinum II Diamine Dichloride><Cisplatin><Cisplatina><Cisplatinum><Clinic><Clinical Evaluation><Clinical Testing><Clinical Trials><Collaborations><Complement><Complement Proteins><Complex><Cysplatyna><Cytokine Inducible SH2-Containing Protein><Cytokine-Inducible Inhibitor of Signaling Type 1B><Cytokine-Inducible Inhibitor of Signaling Type 1B Gene><Cytokine-Inducible SH2-Containing Protein Gene><Cytotoxic cell><DNA><DNA Alteration><DNA Damage Repair><DNA Repair><DNA Repair Pathway><DNA Sequence Alteration><DNA mutation><Death><Defect><Deoxyribonucleic Acid><Development><Devices><Dichlorodiammineplatinum><Engineering><Epithelial ovarian cancer><Fallopian Tubes><Female Reproductive Cancer><Formulation><Funding><G18><G18 Gene><Gene Expression><Genes><Genetic Alteration><Genetic Change><Genetic defect><Genetic mutation><Goals><Grant><Gynecologic Cancer><Gynecological Cancer><HL-A Antigens><HLA Antigens><Harvest><Heterogeneity><Histology><Human Leukocyte Antigens><Immune system><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><Induction Therapy><Innovative Therapy><Inorganic Platinum Compounds><Investigators><K lymphocyte><Leukocyte Antigens><Malignant Cell><Malignant Female Reproductive System Neoplasm><Malignant Gynecologic Neoplasm><Malignant Gynecologic Tumor><Malignant Neoplasm Therapy><Malignant Neoplasm Treatment><Malignant Neoplasms><Malignant Ovarian Neoplasm><Malignant Ovarian Tumor><Malignant Peritoneal Neoplasm><Malignant Tumor><Malignant Tumor of the Female Reproductive System><Malignant Tumor of the Ovary><Malignant neoplasm of ovary><Mammalian Oviducts><Measures><Mentors><MicroRNAs><Microfluidic Device><Microfluidic Lab-On-A-Chip><Microfluidic Microchips><Microfluidics><Mission><Modality><Molecular Analysis><Mutation><NEOADJ><NIH><NK Cells><National Institutes of Health><Natural Killer Cells><Neoadjuvant><Neoadjuvant Therapy><Neoadjuvant Treatment><Newly Diagnosed><Operative Procedures><Operative Surgical Procedures><Organ><Organoids><Ovarian><Ovary Cancer><PARP Inhibitor><PARP-1 inhibitor><PARPi><PDX model><Patient derived xenograft><Patients><Peer Review><Peritoneum Cancer><Peyrone's Chloride><Peyrone's Salt><Phase><Phase 2 Clinical Trials><Phase II Clinical Trials><Platinum><Platinum Agents><Platinum Black><Platinum Compounds><Platinum Diamminodichloride><Poison><Poly(ADP-ribose) Polymerase Inhibitor><Poly(ADP-ribose) polymerase 1 inhibitor><Position><Positioning Attribute><Proliferating><Pt element><R-Series Research Projects><R01 Mechanism><R01 Program><Recurrent Malignant Neoplasm><Recurrent Malignant Tumor><Research><Research Grants><Research Personnel><Research Project Grants><Research Projects><Researchers><Resistance><SN-38><SOCS Gene><Salpinx><Sampling><Sequence Alteration><Serous><Soluble Mpf/Mesothelin-Related Protein><Source><Suppressor of Cytokine Signaling><Suppressor of Cytokine Signaling Gene><Surgical><Surgical Interventions><Surgical Procedure><T-Cells><T-Lymphocyte><TOP1><TOP1 gene><Technology><Testing><Therapeutic><Therapeutic Agents><Therapy Clinical Trials><Time><Toxic Chemical><Toxic Substance><Translational Research><Translational Science><Tumor Cell><United States National Institutes of Health><Unscheduled DNA Synthesis><Uterine Tubes><Vaccines><anti-cancer research><anti-cancer therapy><arm><cancer cell><cancer microenvironment><cancer recurrence><cancer research><cancer therapy><cancer-directed therapy><career><cell based intervention><cell mediated intervention><cell mediated therapies><cell-based therapeutic><cell-based therapy><cellular therapeutic><cellular therapy><chimeric antigen receptor><chimeric antigen receptor engineered natural killer cell><chimeric antigen receptor natural killer cells><cis dichlorodiammineplatinum><cis platinum compound><cis-Diaminedichloroplatinum><cis-Diamminedichloroplatinum><cis-Diamminedichloroplatinum(II)><cis-Dichlorodiammineplatinum(II)><cis-Platinum><clinical test><companion diagnostics><complementation><cytokine><developmental><genome mutation><genomic alteration><gynecologic malignancy><gynecological malignancy><immune suppression><immune suppressive activity><immune suppressive function><immunosuppressive activity><immunosuppressive function><immunosuppressive response><improved><in vivo><induction therapies><inhibitor><inhibitor drug><inhibitor therapeutic><inhibitor therapy><innovate><innovation><innovative><malignancy><mesothelin><miRNA><microfluidic chip><model of animal><mortality><nano particle><nano-sized particle><nanoparticle><nanosized particle><natural killer cells expressing chimeric antigen receptors><natural killer cells with chimeric antigen receptors><neoplasm/cancer><neoplastic cell><new drug treatments><new drugs><new pharmacological therapeutic><new technology><new therapeutics><new therapy><next generation><next generation therapeutics><novel><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel technologies><novel therapeutics><novel therapy><ovarian cancer><ovarian cancer prevention><oviduct><parent grant><patient derived xenograft model><patient response><patient specific response><peritoneal cancer><phase 1 trial><phase 2 trial><phase I trial><phase II protocol><phase II trial><post treatment><pre-clinical><pre-clinical assessment><pre-clinical study><preclinical><preclinical assessment><preclinical study><predict responsiveness><predicting response><programs><research clinical testing><resistant><response><response to therapy><response to treatment><responsive patient><restoration><scRNA sequencing><scRNA-seq><single cell RNA-seq><single cell RNAseq><single cell expression profiling><single cell transcriptomic profiling><single-cell RNA sequencing><small molecule><surgery><targeted agent><therapeutic response><therapy response><three dimensional><thymus derived lymphocyte><toxic compound><translation research><translational investigation><translational pipeline><translational spectrum><treatment response><treatment responsiveness><tumor><tumor microenvironment><µfluidic>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Joann B. Sweasy

UNIVERSITY OF NEBRASKA MEDICAL CENTER, OMAHA, NE

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$191,875
FY 2025

Project Title

Buffett Cancer Center Support Grant

Grant Number:

3P30CA036727-39S1

Activity Code:

P30

Mechanism:

Research Centers

Agency:

NIH

Start Date:

9/5/1997

End Date:

8/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY The Fred & Pamela Buffett Cancer Center (Buffett Cancer Center or BCC), an NCI-designated Cancer Center since 1984, is committed to basic, translational, clinical and population science research, comprehensive educational programs, and outreach to underserved communities in our catch...

Research Terms

<Address><Award><Basic Research><Basic Science><Biological Markers><CCSG><Cancer Biology><Cancer Burden><Cancer Center><Cancer Center Support Grant><Cancer Control><Cancer Control Science><Cancers><Catchment Area><Clinical><Clinical Cancer Center><Clinical Research><Clinical Sciences><Clinical Study><Clinical Trials><Communities><Community Outreach><Development><Direct Costs><Early Diagnosis><Education><Education and Training><Educational aspects><Environment><Faculty Education><Faculty Training><Fostering><Funding><GI cancers><GI malignancies><GI tract cancers><Gastrointestinal Cancer><Gastrointestinal Tract Cancer><Health Care><Health Care Facility><Health Facilities><Intervention><Leadership><Malignant Gastrointestinal Neoplasm><Malignant Neoplasms><Malignant Tumor><Malignant neoplasm of gastrointestinal tract><Medical center><Medicinal Chemistry><Medicine><Mission><Modeling><NCI-Designated Cancer Center><Names><National Cancer Burden><Nebraska><Organoids><Patients><Pharmaceutic Chemistry><Pharmaceutical Chemistry><Physicians><Population Sciences><Position><Positioning Attribute><Prevention><Prognosis><Reporting><Research><Research Infrastructure><Research Peer Review><Research Resources><Research Support><Resource Sharing><Resources><Risk><Role><Scientific Advances and Accomplishments><Synthesis Chemistry><Synthetic Chemistry><Teacher Education><Teacher Educator><Teacher Preparation><Teacher Professional Development><Teacher Training><Tissue Arrays><Tissue Chip><Tissue Microarray><Training and Education><Translational Research><Translational Science><Universities><anti-cancer research><bio-markers><biologic marker><biomarker><cancer care><cancer disparity><cancer education><cancer health disparity><cancer initiation><cancer progression><cancer research><cancer-related health disparity><care facilities><clinical care><community engagement><community partners><community-based partners><computational chemistry><developmental><disparity in cancer><disparity in health><early detection><engagement with communities><faculty development><faculty professional development><gastrointestinal malignancies><health disparity><innovate><innovation><innovative><instructor training><interdisciplinary collaboration><malignancy><member><metabolism measurement><metabolomics><metabonomics><multidisciplinary><name><named><naming><neoplasm progression><neoplasm/cancer><neoplastic progression><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><outreach><patient centered><patient oriented><pre-clinical imaging><preclinical imaging><programs><recruit><research facility><scientific accomplishments><scientific advances><social role><teacher development><transdisciplinary collaboration><translation research><translational cancer research><translational investigation><tumor progression><under served community><underserved community>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

BERNADETTE Marie BODEN-ALBALA

UNIVERSITY OF CALIFORNIA LOS ANGELES, LOS ANGELES, CA

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$133,981
FY 2025

Project Title

UCLA-UCI Center for Eliminating Cardio-Metabolic Disparities in Multi-Ethnic Populations (UC END-DISPARITIES)

Grant Number:

3P50MD017366-05S1

Activity Code:

P50

Mechanism:

Research Centers

Agency:

NIH

Start Date:

9/24/2021

End Date:

6/30/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

Project Summary/Abstract P50 UC END-DISPARITIES UC END-DISPARITIES will address the inequitable multilevel factors that promote cardiometabolic disease, including hypertension, diabetes, and complications such as atherosclerotic vascular disease and chronic kidney disease. These conditions are highl...

Research Terms

<ASCVD><Acceleration><Affect><Aging><American Indian community><Asian><Atherosclerosis><Atherosclerotic Cardiovascular Disease><Award><Behavioral><Biometrics><Biometry><Biostatistics><Black><Black race><California><Cardiometabolic Disease><Cardiometabolic Disorder><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Chronic><Chronic Disease><Chronic Illness><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Clinical Research><Clinical Sciences><Clinical Study><Cognitive Discrimination><Collaborations><Communication><Communities><County><Data Set><Decrease health disparities><Development><Diabetes Mellitus><Disadvantaged><Discrimination><Disparities><Disparity><Economics><Equity><Ethnic Group><Ethnic People><Ethnic Population><Ethnic individual><Ethnicity People><Ethnicity Population><Evaluation><Family><Funding><Future><Goals><Health><Health Policy><Health disparity mitigation><Health disparity reduction><Health equity research><Health system><Heart Vascular><Hypertension><Individual><Individuals from minority><Individuals of minority><Inequity><Infrastructure><Institution><Intervention><Investigators><Latino><Link><Los Angeles><Low income><Lower health disparities><Measurement><Measures><Mentors><Mentorship><Methodology><Minority><Minority Groups><Minority Health Research><Minority People><Minority Population><Minority individual><Minority research><Minority-Serving Institution><Mitigate health disparities><Morbidity><Morbidity - disease rate><NCMHD><NIGMS><NIH><NIMHD><National Center on Minority Health and Health Disparities><National Institute of General Medical Sciences><National Institute of Minority Health and Health Disparities><National Institute on Minority Health and Health Disparities><National Institutes of Health><Oranges><Outcome><Outcomes Research><Pacific Island individual><Pacific Island population><Pacific Islander><Participant><PhenX Toolkit><Phenotypes and eXposures Toolkit><Phenx><Pilot Projects><Population><Postdoc><Postdoctoral Fellow><Public Health><R-Series Research Projects><R01 Mechanism><R01 Program><Reduce health disparities><Research><Research Associate><Research Grants><Research Infrastructure><Research Institute><Research Methodology><Research Methods><Research Personnel><Research Project Grants><Research Projects><Research Resources><Research in health equity><Researchers><Resource Sharing><Resources><Risk><Risk Factors><Stress><Training><Training Programs><Translational Research><Translational Science><United States National Institutes of Health><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Work><allostatic load><atheromatosis><atherosclerotic disease><atherosclerotic vascular disease><cardiometabolic><cardiometabolic risk><cardiometabolism><care outcomes><career><catalyst><chronic disorder><chronic kidney disease><circulatory system><community academic collaboration><community academic partnership><community academic research partnership><community engaged participatory research><community engaged research><community engagement><community partnered research><community university partnership><community-engaged study><community-partnered study><data harmonization><data sharing><design><designing><developmental><diabetes><disease disparity><disease prevention><disorder prevention><disparity in health><economic><engagement with communities><ethnic subgroup><ethnicity group><flexibility><flexible><harmonized data><health IT><health care outcomes><health care policy><health disparity><health equity><health equity-focused research><health information technology><high blood pressure><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><implementation science><improved><inflammation marker><inflammatory marker><innovate><innovation><innovative><intervention design><marginalized group><marginalized individual><marginalized people><marginalized population><meeting><meetings><minority communities><minority institution><mortality><multi-ethnic><multiethnic><patient population><pilot study><post-doc><post-doctoral><post-doctoral trainee><premature><prematurity><prevent><preventing><programs><research and methods><research associates><research in minorities><research on health equity><research on minorities><research related to health equity><research related to minorities><research to attain health equity><research with minorities><social><social genomics><social health determinants><socio-genomics><sociogenomics><structural determinants><structural factors><synergism><therapy design><tool><translation research><translational investigation><treatment design><vulnerable community>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

ARLEEN F. BROWN

UNIVERSITY OF CALIFORNIA LOS ANGELES, LOS ANGELES, CA

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$133,981
FY 2025

Project Title

UCLA-UCI Center for Eliminating Cardio-Metabolic Disparities in Multi-Ethnic Populations (UC END-DISPARITIES)

Grant Number:

3P50MD017366-05S1

Activity Code:

P50

Mechanism:

Research Centers

Agency:

NIH

Start Date:

9/24/2021

End Date:

6/30/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

Project Summary/Abstract P50 UC END-DISPARITIES UC END-DISPARITIES will address the inequitable multilevel factors that promote cardiometabolic disease, including hypertension, diabetes, and complications such as atherosclerotic vascular disease and chronic kidney disease. These conditions are highl...

Research Terms

<ASCVD><Acceleration><Affect><Aging><American Indian community><Asian><Atherosclerosis><Atherosclerotic Cardiovascular Disease><Award><Behavioral><Biometrics><Biometry><Biostatistics><Black><Black race><California><Cardiometabolic Disease><Cardiometabolic Disorder><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Chronic><Chronic Disease><Chronic Illness><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Clinical Research><Clinical Sciences><Clinical Study><Cognitive Discrimination><Collaborations><Communication><Communities><County><Data Set><Decrease health disparities><Development><Diabetes Mellitus><Disadvantaged><Discrimination><Disparities><Disparity><Economics><Equity><Ethnic Group><Ethnic People><Ethnic Population><Ethnic individual><Ethnicity People><Ethnicity Population><Evaluation><Family><Funding><Future><Goals><Health><Health Policy><Health disparity mitigation><Health disparity reduction><Health equity research><Health system><Heart Vascular><Hypertension><Individual><Individuals from minority><Individuals of minority><Inequity><Infrastructure><Institution><Intervention><Investigators><Latino><Link><Los Angeles><Low income><Lower health disparities><Measurement><Measures><Mentors><Mentorship><Methodology><Minority><Minority Groups><Minority Health Research><Minority People><Minority Population><Minority individual><Minority research><Minority-Serving Institution><Mitigate health disparities><Morbidity><Morbidity - disease rate><NCMHD><NIGMS><NIH><NIMHD><National Center on Minority Health and Health Disparities><National Institute of General Medical Sciences><National Institute of Minority Health and Health Disparities><National Institute on Minority Health and Health Disparities><National Institutes of Health><Oranges><Outcome><Outcomes Research><Pacific Island individual><Pacific Island population><Pacific Islander><Participant><PhenX Toolkit><Phenotypes and eXposures Toolkit><Phenx><Pilot Projects><Population><Postdoc><Postdoctoral Fellow><Public Health><R-Series Research Projects><R01 Mechanism><R01 Program><Reduce health disparities><Research><Research Associate><Research Grants><Research Infrastructure><Research Institute><Research Methodology><Research Methods><Research Personnel><Research Project Grants><Research Projects><Research Resources><Research in health equity><Researchers><Resource Sharing><Resources><Risk><Risk Factors><Stress><Training><Training Programs><Translational Research><Translational Science><United States National Institutes of Health><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Work><allostatic load><atheromatosis><atherosclerotic disease><atherosclerotic vascular disease><cardiometabolic><cardiometabolic risk><cardiometabolism><care outcomes><career><catalyst><chronic disorder><chronic kidney disease><circulatory system><community academic collaboration><community academic partnership><community academic research partnership><community engaged participatory research><community engaged research><community engagement><community partnered research><community university partnership><community-engaged study><community-partnered study><data harmonization><data sharing><design><designing><developmental><diabetes><disease disparity><disease prevention><disorder prevention><disparity in health><economic><engagement with communities><ethnic subgroup><ethnicity group><flexibility><flexible><harmonized data><health IT><health care outcomes><health care policy><health disparity><health equity><health equity-focused research><health information technology><high blood pressure><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><implementation science><improved><inflammation marker><inflammatory marker><innovate><innovation><innovative><intervention design><marginalized group><marginalized individual><marginalized people><marginalized population><meeting><meetings><minority communities><minority institution><mortality><multi-ethnic><multiethnic><patient population><pilot study><post-doc><post-doctoral><post-doctoral trainee><premature><prematurity><prevent><preventing><programs><research and methods><research associates><research in minorities><research on health equity><research on minorities><research related to health equity><research related to minorities><research to attain health equity><research with minorities><social><social genomics><social health determinants><socio-genomics><sociogenomics><structural determinants><structural factors><synergism><therapy design><tool><translation research><translational investigation><treatment design><vulnerable community>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Keith C Norris

UNIVERSITY OF CALIFORNIA LOS ANGELES, LOS ANGELES, CA

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$133,981
FY 2025

Project Title

UCLA-UCI Center for Eliminating Cardio-Metabolic Disparities in Multi-Ethnic Populations (UC END-DISPARITIES)

Grant Number:

3P50MD017366-05S1

Activity Code:

P50

Mechanism:

Research Centers

Agency:

NIH

Start Date:

9/24/2021

End Date:

6/30/2027

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

Project Summary/Abstract P50 UC END-DISPARITIES UC END-DISPARITIES will address the inequitable multilevel factors that promote cardiometabolic disease, including hypertension, diabetes, and complications such as atherosclerotic vascular disease and chronic kidney disease. These conditions are highl...

Research Terms

<ASCVD><Acceleration><Affect><Aging><American Indian community><Asian><Atherosclerosis><Atherosclerotic Cardiovascular Disease><Award><Behavioral><Biometrics><Biometry><Biostatistics><Black><Black race><California><Cardiometabolic Disease><Cardiometabolic Disorder><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Chronic><Chronic Disease><Chronic Illness><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Clinical Research><Clinical Sciences><Clinical Study><Cognitive Discrimination><Collaborations><Communication><Communities><County><Data Set><Decrease health disparities><Development><Diabetes Mellitus><Disadvantaged><Discrimination><Disparities><Disparity><Economics><Equity><Ethnic Group><Ethnic People><Ethnic Population><Ethnic individual><Ethnicity People><Ethnicity Population><Evaluation><Family><Funding><Future><Goals><Health><Health Policy><Health disparity mitigation><Health disparity reduction><Health equity research><Health system><Heart Vascular><Hypertension><Individual><Individuals from minority><Individuals of minority><Inequity><Infrastructure><Institution><Intervention><Investigators><Latino><Link><Los Angeles><Low income><Lower health disparities><Measurement><Measures><Mentors><Mentorship><Methodology><Minority><Minority Groups><Minority Health Research><Minority People><Minority Population><Minority individual><Minority research><Minority-Serving Institution><Mitigate health disparities><Morbidity><Morbidity - disease rate><NCMHD><NIGMS><NIH><NIMHD><National Center on Minority Health and Health Disparities><National Institute of General Medical Sciences><National Institute of Minority Health and Health Disparities><National Institute on Minority Health and Health Disparities><National Institutes of Health><Oranges><Outcome><Outcomes Research><Pacific Island individual><Pacific Island population><Pacific Islander><Participant><PhenX Toolkit><Phenotypes and eXposures Toolkit><Phenx><Pilot Projects><Population><Postdoc><Postdoctoral Fellow><Public Health><R-Series Research Projects><R01 Mechanism><R01 Program><Reduce health disparities><Research><Research Associate><Research Grants><Research Infrastructure><Research Institute><Research Methodology><Research Methods><Research Personnel><Research Project Grants><Research Projects><Research Resources><Research in health equity><Researchers><Resource Sharing><Resources><Risk><Risk Factors><Stress><Training><Training Programs><Translational Research><Translational Science><United States National Institutes of Health><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Work><allostatic load><atheromatosis><atherosclerotic disease><atherosclerotic vascular disease><cardiometabolic><cardiometabolic risk><cardiometabolism><care outcomes><career><catalyst><chronic disorder><chronic kidney disease><circulatory system><community academic collaboration><community academic partnership><community academic research partnership><community engaged participatory research><community engaged research><community engagement><community partnered research><community university partnership><community-engaged study><community-partnered study><data harmonization><data sharing><design><designing><developmental><diabetes><disease disparity><disease prevention><disorder prevention><disparity in health><economic><engagement with communities><ethnic subgroup><ethnicity group><flexibility><flexible><harmonized data><health IT><health care outcomes><health care policy><health disparity><health equity><health equity-focused research><health information technology><high blood pressure><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><implementation science><improved><inflammation marker><inflammatory marker><innovate><innovation><innovative><intervention design><marginalized group><marginalized individual><marginalized people><marginalized population><meeting><meetings><minority communities><minority institution><mortality><multi-ethnic><multiethnic><patient population><pilot study><post-doc><post-doctoral><post-doctoral trainee><premature><prematurity><prevent><preventing><programs><research and methods><research associates><research in minorities><research on health equity><research on minorities><research related to health equity><research related to minorities><research to attain health equity><research with minorities><social><social genomics><social health determinants><socio-genomics><sociogenomics><structural determinants><structural factors><synergism><therapy design><tool><translation research><translational investigation><treatment design><vulnerable community>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Suresh S. Ramalingam

EMORY UNIVERSITY, ATLANTA, GA

Exploratory lead · 44/100
Likely hiring
Active award
Team-scale grant
$59,999
FY 2025

Project Title

Winship Cancer Institute Cancer Center Support Grant

Grant Number:

3P30CA138292-16S1

Activity Code:

P30

Mechanism:

Research Centers

Agency:

NIH

Start Date:

4/7/2009

End Date:

3/31/2028

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY/ABSTRACT OVERALL The mission of Winship Cancer Institute of Emory University (Winship) is to discover cures for cancer and inspire hope. Winship is the only NCI-designated comprehensive cancer center in Georgia, the eighth most populous state in the United States, with the second hig...

Research Terms

<AIDS Virus><Acceleration><Acquired Immune Deficiency Syndrome Virus><Acquired Immunodeficiency Syndrome Virus><Address><Area><Award><Basic Research><Basic Science><Black Populations><Black group><Black individual><Black people><Blacks><CCSG><Cancer Burden><Cancer Center Support Grant><Cancer health equity><Cancers><Catchment Area><Clinical><Clinical Sciences><Clinical Trials><Communication><Community Outreach><Comprehensive Cancer Center><Country><Diagnosis><Disease><Disorder><ET-CTN><Early Therapeutic-Clinical Trials Network><Education><Education and Outreach><Education and Training><Educational aspects><Fostering><Funding><Generalized Growth><Growth><HIV><HPV Vaccination><Health><Health Policy><Health Promotion><Hispanic Populations><Hispanic group><Hispanic individual><Hispanic people><Hispanics><Human Immunodeficiency Viruses><Human Papilloma Virus Vaccination><Human Papillomavirus Vaccination><Individual><Infrastructure><Institution><Instruction and Outreach><Intervention><Investigators><Investments><LAV-HTLV-III><Leadership><Legislation><Lymphadenopathy-Associated Virus><Malignant Neoplasms><Malignant Tumor><Malignant Tumor of the Lung><Malignant neoplasm of lung><Manuscripts><Mentorship><Mission><Multiple Myeloma><National Cancer Burden><P50 Mechanism><P50 Program><Patients><Peer Review><Phase><Plasma-Cell Myeloma><Population Sciences><Publishing><Pulmonary Cancer><Pulmonary malignant Neoplasm><QOL><Quality of life><Reporting><Research><Research Personnel><Research Resources><Researchers><Resource Sharing><Resources><Risk><Rural><Salutogenesis><Schools><Science><Screening for cancer><Societies><Specialized Center><Statutes and Laws><Strategic Planning><Time><Tissue Growth><Training><Training and Education><Training and Outreach><Translational Research><Translational Science><Translations><Tutoring and Outreach><Underrepresented Groups><Underrepresented Populations><Underserved Population><United States><Universities><Virus-HIV><anti-cancer research><cancer care><cancer disparity><cancer health disparity><cancer immunology><cancer research><cancer-related health disparity><clinical care><community based organizations><community engagement><community organizations><community partners><community partnership><community-based partners><disparity in cancer><diversity, equity, and inclusiveness><early cancer detection><engagement with communities><equity, diversity, and inclusion><experience><first in man><first-in-human><health care policy><health literacy><improved><innovate><innovation><innovative><leukemia/lymphoma><lung cancer><lymphoma/leukemia><malignancy><member><myeloma><myelomatosis><neoplasm immunology><neoplasm/cancer><new anti-cancer agent><new anticancer agent><new anticancer drug><new antineoplastic><new cancer drug><novel anti-cancer agent><novel anti-cancer drug><novel anticancer agent><novel anticancer drug><novel antineoplastic><novel cancer drug><ontogeny><phase 1 trial><phase I trial><programs><promoting health><screening cancer patients><tobacco control><translation><translation research><translational investigation><treatment trial><tumor immunology><under representation of groups><under represented groups><under represented people><under represented populations><under served group><under served individual><under served people><under served population><underrepresentation of groups><underrepresented people><underserved group><underserved individual><underserved people>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Richard J. Noel

PONCE SCHOOL OF MEDICINE, PONCE, PR

Exploratory lead · 42/100
Large award
Active award
Team-scale grant
$8,382,792
FY 2025

Project Title

PHSU Specialized Center in Health Disparities

Grant Number:

4U54MD007579-40

Activity Code:

U54

Mechanism:

Research Centers

Agency:

NIH

Start Date:

8/25/1997

End Date:

5/31/2027

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.

Project Abstract

SUMMARY OVERALL RENEWAL RCMI CENTER APPLICATION During the last funding cycle, 2019-2024, the PHSU RCMI Center reached important milestones while overcoming challenges caused by natural events. According to the assessment made by the RCMI External Advisory Committee and the External Evaluation Team,...

Research Terms

<Address><Advisory Committees><Amygdala><Amygdaloid Body><Amygdaloid Nucleus><Amygdaloid structure><Area><Asthma><Basic Research><Basic Science><Behavioral><Behavioral Research><Biomedical Research><Blood Neutrophil><Blood Polymorphonuclear Neutrophil><Bronchial Asthma><Chronic stress><Clinical><Clinical Research><Clinical Study><Cocaine use disorder><Communities><Decrease health disparities><Development><Development and Research><Differences between sexes><Differs between sexes><Disease><Disorder><Disparity population><Doctor of Philosophy><EXTMR><Educational Mainstreaming><Environment><Evaluation><Event><Exposure to><Extramural><Extramural Activities><Faculty><Faculty Recruitment><Fostering><Funding><Future><Goals><Health><Health Sciences><Health Services Evaluation><Health Services Research><Health disparity mitigation><Health disparity reduction><Institution><Intervention><Investigators><Journals><Knowledge><Leadership><Lower health disparities><Magazine><Mainstreaming><Marrow Neutrophil><Measures><Medical Care Research><Mentors><Mission><Mitigate health disparities><Modeling><Monitor><NIH><National Institutes of Health><Nature><Neutrophilic Granulocyte><Neutrophilic Leukocyte><Nucleus Accumbens><P50 Mechanism><P50 Program><Peer Review><Persons><Ph.D.><PhD><Pilot Projects><Polymorphonuclear Cell><Polymorphonuclear Leukocytes><Polymorphonuclear Neutrophils><Population><Position><Positioning Attribute><Postdoc><Postdoctoral Fellow><Press Releases><Probability><Productivity><Publications><Puerto Rico><R & D><R&D><R-Series Research Projects><R01 Mechanism><R01 Program><Reduce health disparities><Research><Research Activity><Research Associate><Research Grants><Research Infrastructure><Research Personnel><Research Project Grants><Research Projects><Research Resources><Researchers><Resources><Rodent Model><Role><SYK><SYK gene><Science><Scientific Publication><Seasons><Secure><Series><Sex Differences><Sexual differences><Source><Specialized Center><Spleen Tyrosine Kinase><Strategic Planning><Stress><Task Forces><Technology><Testing><Training><Translational Research><Translational Science><Tyrosine-Protein Kinase SYK><United States National Institutes of Health><Universities><achievement Mainstream Education><advisory team><amygdaloid nuclear complex><assess effectiveness><career><career development><chronic mental illness><collaboration with communities><community based organizations><community collaboration><community empowerment><community engagement><community level disadvantage><community organizations><community-based collaboration><design><designing><determine effectiveness><developmental><disadvantaged community><disadvantaged group><disadvantaged individual><disadvantaged people><disadvantaged population><disadvantaged subgroup><disparities across groups><disparity across subgroups><disparity among groups><disparity among subgroups><disparity between groups><disparity between subgroups><disparity in health><effectiveness assessment><effectiveness evaluation><engagement with communities><evaluate effectiveness><examine effectiveness><experience><extracellular><group disparity><group inequality><group inequity><health disparity><health training><improve minority health><improved><improvement of minority health><inequalities among populations><inequalities between populations><inequalities in populations><inequality across populations><inequality among groups><inequality between groups><inequality in groups><inequities among populations><inequities between populations><inequities in populations><inequity across groups><inequity across populations><inequity between groups><inequity in groups><innovate><innovation><innovative><member><minority health><minority health disparity><neighborhood barrier><neighborhood disadvantage><neighborhood-level barrier><neighborhood-level disadvantage><neutrophil><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><operation><operations><persistent mental illness><pilot study><population inequality><population inequity><post-doc><post-doctoral><post-doctoral trainee><prevent><preventing><programs><recruit><recruit teachers><research and development><research associates><research faculty><serious mental disorder><serious mental illness><services research><severe mental disorder><severe mental illness><sex based differences><sex determination><sex-dependent differences><sex-related differences><sex-specific differences><social media><social role><subgroup disparity><success><teacher recruitment><tool><translation research><translational investigation><unequal group><unequal population>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Kenira J Thompson

PONCE SCHOOL OF MEDICINE, PONCE, PR

Exploratory lead · 42/100
Large award
Active award
Team-scale grant
$8,382,792
FY 2025

Project Title

PHSU Specialized Center in Health Disparities

Grant Number:

4U54MD007579-40

Activity Code:

U54

Mechanism:

Research Centers

Agency:

NIH

Start Date:

8/25/1997

End Date:

5/31/2027

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.

Project Abstract

SUMMARY OVERALL RENEWAL RCMI CENTER APPLICATION During the last funding cycle, 2019-2024, the PHSU RCMI Center reached important milestones while overcoming challenges caused by natural events. According to the assessment made by the RCMI External Advisory Committee and the External Evaluation Team,...

Research Terms

<Address><Advisory Committees><Amygdala><Amygdaloid Body><Amygdaloid Nucleus><Amygdaloid structure><Area><Asthma><Basic Research><Basic Science><Behavioral><Behavioral Research><Biomedical Research><Blood Neutrophil><Blood Polymorphonuclear Neutrophil><Bronchial Asthma><Chronic stress><Clinical><Clinical Research><Clinical Study><Cocaine use disorder><Communities><Decrease health disparities><Development><Development and Research><Differences between sexes><Differs between sexes><Disease><Disorder><Disparity population><Doctor of Philosophy><EXTMR><Educational Mainstreaming><Environment><Evaluation><Event><Exposure to><Extramural><Extramural Activities><Faculty><Faculty Recruitment><Fostering><Funding><Future><Goals><Health><Health Sciences><Health Services Evaluation><Health Services Research><Health disparity mitigation><Health disparity reduction><Institution><Intervention><Investigators><Journals><Knowledge><Leadership><Lower health disparities><Magazine><Mainstreaming><Marrow Neutrophil><Measures><Medical Care Research><Mentors><Mission><Mitigate health disparities><Modeling><Monitor><NIH><National Institutes of Health><Nature><Neutrophilic Granulocyte><Neutrophilic Leukocyte><Nucleus Accumbens><P50 Mechanism><P50 Program><Peer Review><Persons><Ph.D.><PhD><Pilot Projects><Polymorphonuclear Cell><Polymorphonuclear Leukocytes><Polymorphonuclear Neutrophils><Population><Position><Positioning Attribute><Postdoc><Postdoctoral Fellow><Press Releases><Probability><Productivity><Publications><Puerto Rico><R & D><R&D><R-Series Research Projects><R01 Mechanism><R01 Program><Reduce health disparities><Research><Research Activity><Research Associate><Research Grants><Research Infrastructure><Research Personnel><Research Project Grants><Research Projects><Research Resources><Researchers><Resources><Rodent Model><Role><SYK><SYK gene><Science><Scientific Publication><Seasons><Secure><Series><Sex Differences><Sexual differences><Source><Specialized Center><Spleen Tyrosine Kinase><Strategic Planning><Stress><Task Forces><Technology><Testing><Training><Translational Research><Translational Science><Tyrosine-Protein Kinase SYK><United States National Institutes of Health><Universities><achievement Mainstream Education><advisory team><amygdaloid nuclear complex><assess effectiveness><career><career development><chronic mental illness><collaboration with communities><community based organizations><community collaboration><community empowerment><community engagement><community level disadvantage><community organizations><community-based collaboration><design><designing><determine effectiveness><developmental><disadvantaged community><disadvantaged group><disadvantaged individual><disadvantaged people><disadvantaged population><disadvantaged subgroup><disparities across groups><disparity across subgroups><disparity among groups><disparity among subgroups><disparity between groups><disparity between subgroups><disparity in health><effectiveness assessment><effectiveness evaluation><engagement with communities><evaluate effectiveness><examine effectiveness><experience><extracellular><group disparity><group inequality><group inequity><health disparity><health training><improve minority health><improved><improvement of minority health><inequalities among populations><inequalities between populations><inequalities in populations><inequality across populations><inequality among groups><inequality between groups><inequality in groups><inequities among populations><inequities between populations><inequities in populations><inequity across groups><inequity across populations><inequity between groups><inequity in groups><innovate><innovation><innovative><member><minority health><minority health disparity><neighborhood barrier><neighborhood disadvantage><neighborhood-level barrier><neighborhood-level disadvantage><neutrophil><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><operation><operations><persistent mental illness><pilot study><population inequality><population inequity><post-doc><post-doctoral><post-doctoral trainee><prevent><preventing><programs><recruit><recruit teachers><research and development><research associates><research faculty><serious mental disorder><serious mental illness><services research><severe mental disorder><severe mental illness><sex based differences><sex determination><sex-dependent differences><sex-related differences><sex-specific differences><social media><social role><subgroup disparity><success><teacher recruitment><tool><translation research><translational investigation><unequal group><unequal population>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Lee Ellen Buenconsejo-Lum

UNIVERSITY OF HAWAII AT MANOA, HONOLULU, HI

Exploratory lead · 42/100
Large award
Active award
Team-scale grant
$4,896,177
FY 2025

Project Title

Ola HAWAII

Grant Number:

5U54MD007601-39

Activity Code:

U54

Mechanism:

Research Centers

Agency:

NIH

Start Date:

9/23/1997

End Date:

5/31/2027

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY/ABSTRACT With continued support from the National Institute on Minority Health and Health Disparities (NIMHD) through the RCMI U54 RFA-MD-22-002, the goal of Ola HAWAII is to improve minority health and reduce health disparities for those communities in Hawaii which suffer disproport...

Research Terms

<Acceleration><Address><Area><Basic Research><Basic Science><Behavioral Research><Biomedical Research><Burn injury><Burns><COVID-19><CV-19><Cancers><Cardiovascular Diseases><Climacteric><Clinical Research><Clinical Study><Collaborations><Communities><Community Participation><Core Facility><Coronavirus Infectious Disease 2019><Decrease health disparities><Diabetes Mellitus><Disparities><Disparity><Ethnic Group><Ethnic People><Ethnic Population><Ethnic individual><Ethnicity People><Ethnicity Population><Evaluation><Faculty><Filipino><Funding><Goals><Hawaii><Hawaiian><Health><Health Disparities Research><Health Policy><Health disparities related research><Health disparity mitigation><Health disparity reduction><Inequality><Institution><Investigators><Island><Lead><Letters><Lower health disparities><Malignant Neoplasms><Malignant Tumor><Measures><Mentors><Minority-Serving Institution><Mitigate health disparities><NCMHD><NIMHD><Names><National Center on Minority Health and Health Disparities><National Institute of Minority Health and Health Disparities><National Institute on Minority Health and Health Disparities><Native Hawaiian and Other Pacific Islander><Native Hawaiian and Pacific Islander><Native Hawaiian or Other Pacific Islander><Native Hawaiian or Pacific Islander><Outcome><Outcomes Research><P50 Mechanism><P50 Program><Pb element><Pilot Projects><Policies><Policy Developments><Postdoc><Postdoctoral Fellow><Principal Investigator><Process><Productivity><Public Health><Racial Group><Reduce health disparities><Research><Research Associate><Research Personnel><Research Resources><Researchers><Resource Allocation><Resource Sharing><Resources><Services><Specialized Center><Translations><Trust><Underserved Population><Universities><Work><access to health care><accessibility of health care><accessibility to health care><aspirate><base><bases><burned><cardiovascular disorder><collaboration with communities><community collaboration><community-based collaboration><coronavirus disease 2019><coronavirus disease-19><coronavirus infectious disease-19><diabetes><disparity in health><ethnic subgroup><ethnicity group><healing><health care access><health care availability><health care policy><health care service access><health care service availability><health disparities science><health disparity><health equity><heavy metal Pb><heavy metal lead><improve minority health><improved><improvement of minority health><innovate><innovation><innovative><institutional capacity><life change><malignancy><medical college><medical schools><medically under served><medically underserved><minority health><minority health disparity><minority institution><name><named><naming><neoplasm/cancer><new approaches><novel approaches><novel strategies><novel strategy><pilot study><post-doc><post-doctoral><post-doctoral trainee><programs><racial population><racial subgroup><recruit><research associates><research facility><school of medicine><success><translation><under served community><under served group><under served individual><under served people><under served population><underserved community><underserved group><underserved individual><underserved people>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jerris Robert Hedges

UNIVERSITY OF HAWAII AT MANOA, HONOLULU, HI

Exploratory lead · 42/100
Large award
Active award
Team-scale grant
$4,896,177
FY 2025

Project Title

Ola HAWAII

Grant Number:

5U54MD007601-39

Activity Code:

U54

Mechanism:

Research Centers

Agency:

NIH

Start Date:

9/23/1997

End Date:

5/31/2027

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY/ABSTRACT With continued support from the National Institute on Minority Health and Health Disparities (NIMHD) through the RCMI U54 RFA-MD-22-002, the goal of Ola HAWAII is to improve minority health and reduce health disparities for those communities in Hawaii which suffer disproport...

Research Terms

<Acceleration><Address><Area><Basic Research><Basic Science><Behavioral Research><Biomedical Research><Burn injury><Burns><COVID-19><CV-19><Cancers><Cardiovascular Diseases><Climacteric><Clinical Research><Clinical Study><Collaborations><Communities><Community Participation><Core Facility><Coronavirus Infectious Disease 2019><Decrease health disparities><Diabetes Mellitus><Disparities><Disparity><Ethnic Group><Ethnic People><Ethnic Population><Ethnic individual><Ethnicity People><Ethnicity Population><Evaluation><Faculty><Filipino><Funding><Goals><Hawaii><Hawaiian><Health><Health Disparities Research><Health Policy><Health disparities related research><Health disparity mitigation><Health disparity reduction><Inequality><Institution><Investigators><Island><Lead><Letters><Lower health disparities><Malignant Neoplasms><Malignant Tumor><Measures><Mentors><Minority-Serving Institution><Mitigate health disparities><NCMHD><NIMHD><Names><National Center on Minority Health and Health Disparities><National Institute of Minority Health and Health Disparities><National Institute on Minority Health and Health Disparities><Native Hawaiian and Other Pacific Islander><Native Hawaiian and Pacific Islander><Native Hawaiian or Other Pacific Islander><Native Hawaiian or Pacific Islander><Outcome><Outcomes Research><P50 Mechanism><P50 Program><Pb element><Pilot Projects><Policies><Policy Developments><Postdoc><Postdoctoral Fellow><Principal Investigator><Process><Productivity><Public Health><Racial Group><Reduce health disparities><Research><Research Associate><Research Personnel><Research Resources><Researchers><Resource Allocation><Resource Sharing><Resources><Services><Specialized Center><Translations><Trust><Underserved Population><Universities><Work><access to health care><accessibility of health care><accessibility to health care><aspirate><base><bases><burned><cardiovascular disorder><collaboration with communities><community collaboration><community-based collaboration><coronavirus disease 2019><coronavirus disease-19><coronavirus infectious disease-19><diabetes><disparity in health><ethnic subgroup><ethnicity group><healing><health care access><health care availability><health care policy><health care service access><health care service availability><health disparities science><health disparity><health equity><heavy metal Pb><heavy metal lead><improve minority health><improved><improvement of minority health><innovate><innovation><innovative><institutional capacity><life change><malignancy><medical college><medical schools><medically under served><medically underserved><minority health><minority health disparity><minority institution><name><named><naming><neoplasm/cancer><new approaches><novel approaches><novel strategies><novel strategy><pilot study><post-doc><post-doctoral><post-doctoral trainee><programs><racial population><racial subgroup><recruit><research associates><research facility><school of medicine><success><translation><under served community><under served group><under served individual><under served people><under served population><underserved community><underserved group><underserved individual><underserved people>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Edwin Duncan Charlebois

UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, SAN FRANCISCO, CA

Exploratory lead · 42/100
Large award
Active award
Team-scale grant
$4,500,000
FY 2025

Project Title

Research Coordinating Center to Reduce Disparities in Multiple Chronic Diseases (RCC RD-MCD)

Grant Number:

5U24MD017250-05

Activity Code:

U24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

9/24/2021

End Date:

6/30/2027

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.

Project Abstract

SUMMARY Significant disparities in prevention, treatment, and management of multiple chronic diseases exist along intersecting racial, cultural, socio-economic, and vulnerable population contextual lines; community engagement and culturally informed multilevel approaches are required to effectively ...

Research Terms

<Acceleration><Affect><African American><Afro American><Afroamerican><Alaska Indian><Alaska Native><Alaskan American><Alaskan Indian><Alaskan Native><Alaskan Native American><Asian><COVID-19><CV-19><California><Chronic><Chronic Disease><Chronic Illness><Cities><Clinical Trials Data Monitoring Committees><Clinical Trials Design><Collaborations><Collection><Common Data Element><Communication><Communities><Community Networks><Community of Practice><Coronavirus Infectious Disease 2019><Country><Data><Data Monitoring Committees><Data Science><Data and Safety Monitoring Boards><Decrease disparity><Development><Disparities><Disparity><Education><Educational aspects><Educational workshop><Evaluation><Funding><Gender and Sexual Minorities><Geography><Goals><Health><Health Disparities Research><Health Sciences><Health disparities related research><Hispanic><Homelessness><Individual><Integrated Health Care Systems><Intervention><Intervention Trial><Interventional trial><Investigators><Latino><Lower disparity><Mentors><Methods><Minority-Serving Institution><Monitor><NCMHD><NIH><NIMHD><National Center on Minority Health and Health Disparities><National Institute of Minority Health and Health Disparities><National Institute on Minority Health and Health Disparities><National Institutes of Health><Native American><Pacific Island individual><Pacific Island population><Pacific Islander><Persons><PhenX Toolkit><Phenotypes and eXposures Toolkit><Phenx><Population><Prevention><Race><Races><Records><Research><Research Design><Research Personnel><Research Resources><Researchers><Resource Sharing><Resources><Safety Monitoring Boards><San Francisco><Secure><Sexual and Gender Minorities><Site><Standardization><Statistical Data Analyses><Statistical Data Analysis><Statistical Data Interpretation><Study Type><Underserved Population><United States National Institutes of Health><Universities><Vulnerable Populations><Workshop><biomed informatics><biomedical informatics><chronic disorder><co-morbid><co-morbidity><community advisory board><community advisory committee><community advisory panel><community engaged participatory research><community engaged research><community engagement><community partnered research><community partners><community partnership><community-based partners><community-engaged study><community-partnered study><comorbidity><coronavirus disease 2019><coronavirus disease-19><coronavirus infectious disease-19><data management><data sharing><data standardization><data standards><data warehouse><design><designing><developmental><disease disparity><disparity reduction><education research><engagement with communities><experience><flexibility><flexible><health disparities science><homeless><houselessness><human subject><implementation science><instrument><integrated health system><integrated system of care><meeting><meetings><member><minority health><minority health disparity><minority institution><mitigate disparity><operation><operations><programs><racial><racial background><racial origin><reduce disparity><reduction in disparity><response><skill acquisition><skill development><skills><social health determinants><socio-economic><socio-economically><socioeconomically><socioeconomics><statistical analysis><study design><tool><under served group><under served individual><under served people><under served population><underserved group><underserved individual><underserved people><unhoused><vulnerable group><vulnerable individual><vulnerable people><web site><webinar><website><work group><working group>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

STUART A GANSKY

UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, SAN FRANCISCO, CA

Exploratory lead · 42/100
Large award
Active award
Team-scale grant
$4,500,000
FY 2025

Project Title

Research Coordinating Center to Reduce Disparities in Multiple Chronic Diseases (RCC RD-MCD)

Grant Number:

5U24MD017250-05

Activity Code:

U24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

9/24/2021

End Date:

6/30/2027

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.

Project Abstract

SUMMARY Significant disparities in prevention, treatment, and management of multiple chronic diseases exist along intersecting racial, cultural, socio-economic, and vulnerable population contextual lines; community engagement and culturally informed multilevel approaches are required to effectively ...

Research Terms

<Acceleration><Affect><African American><Afro American><Afroamerican><Alaska Indian><Alaska Native><Alaskan American><Alaskan Indian><Alaskan Native><Alaskan Native American><Asian><COVID-19><CV-19><California><Chronic><Chronic Disease><Chronic Illness><Cities><Clinical Trials Data Monitoring Committees><Clinical Trials Design><Collaborations><Collection><Common Data Element><Communication><Communities><Community Networks><Community of Practice><Coronavirus Infectious Disease 2019><Country><Data><Data Monitoring Committees><Data Science><Data and Safety Monitoring Boards><Decrease disparity><Development><Disparities><Disparity><Education><Educational aspects><Educational workshop><Evaluation><Funding><Gender and Sexual Minorities><Geography><Goals><Health><Health Disparities Research><Health Sciences><Health disparities related research><Hispanic><Homelessness><Individual><Integrated Health Care Systems><Intervention><Intervention Trial><Interventional trial><Investigators><Latino><Lower disparity><Mentors><Methods><Minority-Serving Institution><Monitor><NCMHD><NIH><NIMHD><National Center on Minority Health and Health Disparities><National Institute of Minority Health and Health Disparities><National Institute on Minority Health and Health Disparities><National Institutes of Health><Native American><Pacific Island individual><Pacific Island population><Pacific Islander><Persons><PhenX Toolkit><Phenotypes and eXposures Toolkit><Phenx><Population><Prevention><Race><Races><Records><Research><Research Design><Research Personnel><Research Resources><Researchers><Resource Sharing><Resources><Safety Monitoring Boards><San Francisco><Secure><Sexual and Gender Minorities><Site><Standardization><Statistical Data Analyses><Statistical Data Analysis><Statistical Data Interpretation><Study Type><Underserved Population><United States National Institutes of Health><Universities><Vulnerable Populations><Workshop><biomed informatics><biomedical informatics><chronic disorder><co-morbid><co-morbidity><community advisory board><community advisory committee><community advisory panel><community engaged participatory research><community engaged research><community engagement><community partnered research><community partners><community partnership><community-based partners><community-engaged study><community-partnered study><comorbidity><coronavirus disease 2019><coronavirus disease-19><coronavirus infectious disease-19><data management><data sharing><data standardization><data standards><data warehouse><design><designing><developmental><disease disparity><disparity reduction><education research><engagement with communities><experience><flexibility><flexible><health disparities science><homeless><houselessness><human subject><implementation science><instrument><integrated health system><integrated system of care><meeting><meetings><member><minority health><minority health disparity><minority institution><mitigate disparity><operation><operations><programs><racial><racial background><racial origin><reduce disparity><reduction in disparity><response><skill acquisition><skill development><skills><social health determinants><socio-economic><socio-economically><socioeconomically><socioeconomics><statistical analysis><study design><tool><under served group><under served individual><under served people><under served population><underserved group><underserved individual><underserved people><unhoused><vulnerable group><vulnerable individual><vulnerable people><web site><webinar><website><work group><working group>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Kim Felder Rhoads

UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, SAN FRANCISCO, CA

Exploratory lead · 42/100
Large award
Active award
Team-scale grant
$4,500,000
FY 2025

Project Title

Research Coordinating Center to Reduce Disparities in Multiple Chronic Diseases (RCC RD-MCD)

Grant Number:

5U24MD017250-05

Activity Code:

U24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

9/24/2021

End Date:

6/30/2027

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.

Project Abstract

SUMMARY Significant disparities in prevention, treatment, and management of multiple chronic diseases exist along intersecting racial, cultural, socio-economic, and vulnerable population contextual lines; community engagement and culturally informed multilevel approaches are required to effectively ...

Research Terms

<Acceleration><Affect><African American><Afro American><Afroamerican><Alaska Indian><Alaska Native><Alaskan American><Alaskan Indian><Alaskan Native><Alaskan Native American><Asian><COVID-19><CV-19><California><Chronic><Chronic Disease><Chronic Illness><Cities><Clinical Trials Data Monitoring Committees><Clinical Trials Design><Collaborations><Collection><Common Data Element><Communication><Communities><Community Networks><Community of Practice><Coronavirus Infectious Disease 2019><Country><Data><Data Monitoring Committees><Data Science><Data and Safety Monitoring Boards><Decrease disparity><Development><Disparities><Disparity><Education><Educational aspects><Educational workshop><Evaluation><Funding><Gender and Sexual Minorities><Geography><Goals><Health><Health Disparities Research><Health Sciences><Health disparities related research><Hispanic><Homelessness><Individual><Integrated Health Care Systems><Intervention><Intervention Trial><Interventional trial><Investigators><Latino><Lower disparity><Mentors><Methods><Minority-Serving Institution><Monitor><NCMHD><NIH><NIMHD><National Center on Minority Health and Health Disparities><National Institute of Minority Health and Health Disparities><National Institute on Minority Health and Health Disparities><National Institutes of Health><Native American><Pacific Island individual><Pacific Island population><Pacific Islander><Persons><PhenX Toolkit><Phenotypes and eXposures Toolkit><Phenx><Population><Prevention><Race><Races><Records><Research><Research Design><Research Personnel><Research Resources><Researchers><Resource Sharing><Resources><Safety Monitoring Boards><San Francisco><Secure><Sexual and Gender Minorities><Site><Standardization><Statistical Data Analyses><Statistical Data Analysis><Statistical Data Interpretation><Study Type><Underserved Population><United States National Institutes of Health><Universities><Vulnerable Populations><Workshop><biomed informatics><biomedical informatics><chronic disorder><co-morbid><co-morbidity><community advisory board><community advisory committee><community advisory panel><community engaged participatory research><community engaged research><community engagement><community partnered research><community partners><community partnership><community-based partners><community-engaged study><community-partnered study><comorbidity><coronavirus disease 2019><coronavirus disease-19><coronavirus infectious disease-19><data management><data sharing><data standardization><data standards><data warehouse><design><designing><developmental><disease disparity><disparity reduction><education research><engagement with communities><experience><flexibility><flexible><health disparities science><homeless><houselessness><human subject><implementation science><instrument><integrated health system><integrated system of care><meeting><meetings><member><minority health><minority health disparity><minority institution><mitigate disparity><operation><operations><programs><racial><racial background><racial origin><reduce disparity><reduction in disparity><response><skill acquisition><skill development><skills><social health determinants><socio-economic><socio-economically><socioeconomically><socioeconomics><statistical analysis><study design><tool><under served group><under served individual><under served people><under served population><underserved group><underserved individual><underserved people><unhoused><vulnerable group><vulnerable individual><vulnerable people><web site><webinar><website><work group><working group>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

JOHN D. CARPTEN

UNIVERSITY OF SOUTHERN CALIFORNIA, Los Angeles, CA

Exploratory lead · 42/100
Large award
Active award
Team-scale grant
$3,712,500
FY 2025

Project Title

USC PE-GCS: Optimizing Engagement of Hispanic Colorectal Cancer Patients in Cancer Genomic Characterization Studies

Grant Number:

5U2CCA252971-05

Activity Code:

U2C

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

9/22/2021

End Date:

8/31/2027

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Colorectal cancer (CRC) is the second leading cause of cancer-related deaths in the US. Populations exhibiting variability in colorectal cancer outcomes, especially those experiencing higher incidence rates and early-onset CRC, require more thorough genomic characterization. Current genomic research...

Research Terms

<Address><Behavioral Sciences><Biological><Biomedical Research><Cancer Cause><Cancer Etiology><Cancers><Cessation of life><Clinical><Collaborations><Colorectal Cancer><Communication><Communities><Consent><Data><Data Analyses><Data Analysis><Data Bases><Data Collection><Databases><Death><Ensure><Exhibits><Genomics><Goals><Hispanic><Incidence><Individual><Information Dissemination><Investigators><Knowledge><Malignant Neoplasms><Malignant Tumor><Methodology><Methods><Molecular><Outcome><Outcomes Research><P50 Mechanism><P50 Program><Participant><Pathway interactions><Patient Preferences><Patient Recruitments><Patient Representative><Patients><Population><Precision Medicine Initiative><Process><Research><Research Personnel><Researchers><Risk><Specialized Center><Standardization><Technology><Testing><Variant><Variation><biologic><cancer cell genome><cancer genome><cancer genomics><colon cancer patients><colorectal cancer patients><data base><data interpretation><design><designing><dissemination of results><early colo-rectal cancer><early colorectal cancer><early onset><early onset colo-rectal cancer><early onset colorectal cancer><experience><genome sequencing><genomic profiles><improved><individual patient><malignancy><neoplasm/cancer><oncogenomics><outreach><participant engagement><participant recruitment><pathway><patient engagement><recruit><research study><tumor genome><young colo-rectal cancer><young colorectal cancer><young onset colo-rectal cancer><young onset colorectal cancer>
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HEINZ JOSEF LENZ

UNIVERSITY OF SOUTHERN CALIFORNIA, Los Angeles, CA

Exploratory lead · 42/100
Large award
Active award
Team-scale grant
$3,712,500
FY 2025

Project Title

USC PE-GCS: Optimizing Engagement of Hispanic Colorectal Cancer Patients in Cancer Genomic Characterization Studies

Grant Number:

5U2CCA252971-05

Activity Code:

U2C

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

9/22/2021

End Date:

8/31/2027

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Colorectal cancer (CRC) is the second leading cause of cancer-related deaths in the US. Populations exhibiting variability in colorectal cancer outcomes, especially those experiencing higher incidence rates and early-onset CRC, require more thorough genomic characterization. Current genomic research...

Research Terms

<Address><Behavioral Sciences><Biological><Biomedical Research><Cancer Cause><Cancer Etiology><Cancers><Cessation of life><Clinical><Collaborations><Colorectal Cancer><Communication><Communities><Consent><Data><Data Analyses><Data Analysis><Data Bases><Data Collection><Databases><Death><Ensure><Exhibits><Genomics><Goals><Hispanic><Incidence><Individual><Information Dissemination><Investigators><Knowledge><Malignant Neoplasms><Malignant Tumor><Methodology><Methods><Molecular><Outcome><Outcomes Research><P50 Mechanism><P50 Program><Participant><Pathway interactions><Patient Preferences><Patient Recruitments><Patient Representative><Patients><Population><Precision Medicine Initiative><Process><Research><Research Personnel><Researchers><Risk><Specialized Center><Standardization><Technology><Testing><Variant><Variation><biologic><cancer cell genome><cancer genome><cancer genomics><colon cancer patients><colorectal cancer patients><data base><data interpretation><design><designing><dissemination of results><early colo-rectal cancer><early colorectal cancer><early onset><early onset colo-rectal cancer><early onset colorectal cancer><experience><genome sequencing><genomic profiles><improved><individual patient><malignancy><neoplasm/cancer><oncogenomics><outreach><participant engagement><participant recruitment><pathway><patient engagement><recruit><research study><tumor genome><young colo-rectal cancer><young colorectal cancer><young onset colo-rectal cancer><young onset colorectal cancer>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Sherry Ann McKee

YALE UNIVERSITY, NEW HAVEN, CT

Exploratory lead · 42/100
Large award
Active award
Team-scale grant
$1,500,000
FY 2025

Project Title

Yale-SCORE on Sex Differences in Alcohol Use Disorder

Grant Number:

2U54AA027989-06

Activity Code:

U54

Mechanism:

Research Centers

Agency:

NIH

Start Date:

3/10/2020

End Date:

8/31/2030

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.

Project Abstract

The Yale-SCORE (RFA-OD-24-014) provides a nexus for a successful team of leading clinical and basic science experts to pursue an interdisciplinary, translational, cross-species program of research aimed at identifying novel therapeutics to address the recent surge in rates of high-risk drinking in w...

Research Terms

<AODR death rate><AODR mortality><Address><Affect><Alcohol Chemical Class><Alcohol Drinking><Alcohol consumption><Alcohol or Other Drug Related death rate><Alcohol or Other Drug Related mortality><Alcohols><Award><Basic Research><Basic Science><Behavioral><Brain><Brain Nervous System><COBRE><Cancers><Cardiovascular Diseases><Center of Biomedical Research Excellence><Centers of Research Excellence><Clinical Sciences><Cognitive deficits><Collaborations><Communities><Connecticut><Consultations><Darkness><Data><Development><Differences between sexes><Differs between sexes><Drugs><Encephalon><Ensure><Environment><EtOH drinking><EtOH use><FDA approved><Faculty><Faculty Education><Faculty Training><Female Health><Funding><Goals><Gonadal Steroid Hormones><HPA axis><Health><Health Care Professional><Health Professional><Immune><Immunes><Infrastructure><Institution><Investigators><Laboratories><Leadership><Malignant Neoplasms><Malignant Tumor><Medication><Mentors><Modeling><Morbidity><Morbidity - disease rate><NIAAA><National Institute on Alcohol Abuse and Alcoholism><Negative Reinforcements><Neurobiology><Neuroimmune><Neurosciences><P50 Mechanism><P50 Program><PET><PET Scan><PET imaging><PETSCAN><PETT><Pharmaceutical Preparations><Policies><Position><Positioning Attribute><Positive Reinforcements><Positron Emission Tomography Medical Imaging><Positron Emission Tomography Scan><Positron-Emission Tomography><Provider><Psychiatry><Public Health><Publications><Rad.-PET><Research><Research Personnel><Research Priority><Research Resources><Researchers><Resources><Rewards><Risk><Role><Sampling><Science><Scientific Publication><Sex Differences><Sex Hormones><Sex Steroid Hormones><Sexual differences><Side><Specialized Center><Strategic Planning><Stress><Structure><Substance abuse problem><Teacher Education><Teacher Educator><Teacher Preparation><Teacher Professional Development><Teacher Training><Training><Training Programs><Translational Research><Translational Science><United States><Withdrawal><Woman><Women's Health><abuse of substances><addiction><addictive disorder><alcohol abuse therapy><alcohol abuse treatment><alcohol ingestion><alcohol intake><alcohol product use><alcohol related mortality><alcohol treatment><alcohol use><alcohol use disorder><alcoholic beverage consumption><alcoholic drink intake><at-risk drinking><behavioral pharmacology><biological sex as a modifier><brain atrophy><cardiovascular disorder><cerebral atrophy><clinical center><clinical investigation><cognitive defects><comparing females and males><comparing women and men><consultation><cortical atrophy><customized therapy><customized treatment><developmental><drinking><drug/agent><economic cost><efficacious therapy><efficacious treatment><ethanol consumption><ethanol drinking><ethanol ingestion><ethanol intake><ethanol product use><ethanol use><ethanol use disorder><experience><faculty development><faculty professional development><faculty support><female treatment><females compared to males><females compared with males><females versus males><females vs. males><gonadal steroids><hepatic inflammation><heuristics><high risk drinking><hypothalamic-pituitary-adrenal (HPA) axis><hypothalamic-pituitary-adrenal axis><hypothalmus-pituitary-adrenal axis><improved><individualized medicine><individualized patient treatment><individualized therapeutic strategy><individualized therapy><individualized treatment><inflamed liver><insight><instructor training><liver inflammation><malignancy><member><men><mortality><negative affect><negative affectivity><neoplasm/cancer><neural adaptation><neuroadaptation><neurobiological><neurochemical><neurochemistry><neuron toxicity><neuronal toxicity><neurotoxicity><new drug target><new drug treatments><new druggable target><new drugs><new pharmacological therapeutic><new pharmacotherapy target><new therapeutic target><new therapeutics><new therapy><new therapy target><next generation><next generation therapeutics><novel drug target><novel drug treatments><novel druggable target><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel pharmacotherapy target><novel therapeutic target><novel therapeutics><novel therapy><novel therapy target><outreach><patient specific therapies><patient specific treatment><pharmacobehavioral><positron emission tomographic (PET) imaging><positron emission tomographic imaging><positron emitting tomography><precision medicine><precision-based medicine><preventable death><preventable mortality><programs><risky drinking><sex><sex as a biological factor><sex as a biological measure><sex as a biological risk factor><sex as a biological variable><sex as a biological variance><sex as a biologically significant variable><sex as a fundamental variable><sex based differences><sex steroid><sex-dependent differences><sex-related differences><sex-specific differences><social role><substance abuse><success><tailored medical treatment><tailored therapy><tailored treatment><teacher development><therapeutic agent development><therapeutic development><therapeutic target><translation research><translation strategy><translational approach><translational investigation><translational investigator><translational researcher><translational scientist><translational strategy><treat females><treat women><treatment among females><treatment among women><treatment in females><treatment in women><unique treatment><women compared to men><women compared with men><women versus men><women vs. men><women's treatment>
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Cecile Delille Lahiri

EMORY UNIVERSITY, ATLANTA, GA

Exploratory lead · 42/100
Large award
Active award
Team-scale grant
$1,499,999
FY 2025

Project Title

Emory Specialized Center of Research Excellence (SCORE) on Sex Differences

Grant Number:

2U54AG062334-06

Activity Code:

U54

Mechanism:

Research Centers

Agency:

NIH

Start Date:

9/30/2018

End Date:

7/31/2030

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.

Project Abstract

The overarching goal of this Specialized Centers of Research Excellence on Sex Differences (Emory SCORE) renewal application is to advance women’s health through a comprehensive investigation of the influence of sex on infectious diseases. A unifying theme of our program will be to promote the norma...

Research Terms

<AIDS><AIDS Virus><Acceleration><Acquired Immune Deficiency><Acquired Immune Deficiency Syndrome><Acquired Immune Deficiency Syndrome Virus><Acquired Immunodeficiency Syndrome><Acquired Immunodeficiency Syndrome Virus><Administrative Supplement><Age related comorbidities><Aging><Aquadiol><Award><Bioinformatics><Bioinformatics core><Bioinformatics research core><Bioinformatics resource core><Biometrics><Biometry><Biostatistics><Brain><Brain Nervous System><COBRE><Center of Biomedical Research Excellence><Centers of Research Excellence><Chronic><Communicable Diseases><Data><Development><Diet><Differences between sexes><Differs between sexes><Dimenformon><Diogyn><Diogynets><EXTMR><Educational workshop><Encephalon><Ensure><Environment><Estrace><Estradiol><Estradiol-17 beta><Estradiol-17beta><Estraldine><Estrogen Receptors><Estrogens><Evaluation><Extramural><Extramural Activities><Female Health><Fostering><Funding><Goals><Grant><HIV><Heart><High Risk Woman><Human Immunodeficiency Viruses><Immune><Immune Cell Activation><Immunes><Immunity><Inequity><Infectious Diseases><Infectious Disorder><Institution><International><Intestinal Leakage><Investigation><LAV-HTLV-III><Leadership><Leaky Gut><Long-term infection><Lymphadenopathy-Associated Virus><Mediating><Mentors><Modeling><NIH><National Institutes of Health><Organ><Outcome><Ovarian><Ovocyclin><Ovocylin><P50 Mechanism><P50 Program><Pathogenesis><Pathology><Pathway interactions><Policies><Polishes><Position><Positioning Attribute><Probiotics><Progynon><Psychosocial Factor><Publications><R-Series Research Projects><R01 Mechanism><R01 Program><Reproducibility><Research><Research Grants><Research Infrastructure><Research Project Grants><Research Projects><Research Resources><Resources><Risk><Role><Science><Scientific Publication><Series><Sex Differences><Sexual differences><Sight><Specialized Center><Therapeutic Estradiol><Therapeutic Estrogen><Time><Training><United States National Institutes of Health><Universities><Virus-HIV><Vision><Woman><Women's Health><Work><Workshop><age associated comorbidities><at-risk females><at-risk women><biobehavior><biobehavioral><biological sex><biological sex as a modifier><bone><bone loss><career><career development><chronic infection><cohort><conference><convention><data management><decreased ovarian reserve><develop therapy><developmental><diets><differences in health><diminished ovarian reserve><dysbacteriosis><dysbiosis><dysbiotic><fecal microbial transplantation><fecal microbiome transplantation><fecal microbiota transplant><fecal microbiota transplantation><fecal transplant><fecal transplantation><females at high risk><health difference><high risk females><immune activation><immune reconstitution><improved><injury to organs><interdisciplinary collaboration><interest><intervention development><leadership development><microbial><microbial host><microbial imbalance><news><next generation><organ injury><pathogen><pathway><persistent infection><programs><psychosocial variables><response><sex><sex as a biological factor><sex as a biological measure><sex as a biological risk factor><sex as a biological variable><sex as a biological variance><sex as a biologically significant variable><sex as a fundamental variable><sex based differences><sex-dependent differences><sex-related differences><sex-specific differences><social factors><social role><summit><symposia><symposium><systemic inflammation><systemic inflammatory response><therapy development><transdisciplinary collaboration><treatment development><visual function><women at high risk>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Vasiliki Michopoulos

EMORY UNIVERSITY, ATLANTA, GA

Exploratory lead · 42/100
Large award
Active award
Team-scale grant
$1,499,999
FY 2025

Project Title

Emory Specialized Center of Research Excellence (SCORE) on Sex Differences

Grant Number:

2U54AG062334-06

Activity Code:

U54

Mechanism:

Research Centers

Agency:

NIH

Start Date:

9/30/2018

End Date:

7/31/2030

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.

Project Abstract

The overarching goal of this Specialized Centers of Research Excellence on Sex Differences (Emory SCORE) renewal application is to advance women’s health through a comprehensive investigation of the influence of sex on infectious diseases. A unifying theme of our program will be to promote the norma...

Research Terms

<AIDS><AIDS Virus><Acceleration><Acquired Immune Deficiency><Acquired Immune Deficiency Syndrome><Acquired Immune Deficiency Syndrome Virus><Acquired Immunodeficiency Syndrome><Acquired Immunodeficiency Syndrome Virus><Administrative Supplement><Age related comorbidities><Aging><Aquadiol><Award><Bioinformatics><Bioinformatics core><Bioinformatics research core><Bioinformatics resource core><Biometrics><Biometry><Biostatistics><Brain><Brain Nervous System><COBRE><Center of Biomedical Research Excellence><Centers of Research Excellence><Chronic><Communicable Diseases><Data><Development><Diet><Differences between sexes><Differs between sexes><Dimenformon><Diogyn><Diogynets><EXTMR><Educational workshop><Encephalon><Ensure><Environment><Estrace><Estradiol><Estradiol-17 beta><Estradiol-17beta><Estraldine><Estrogen Receptors><Estrogens><Evaluation><Extramural><Extramural Activities><Female Health><Fostering><Funding><Goals><Grant><HIV><Heart><High Risk Woman><Human Immunodeficiency Viruses><Immune><Immune Cell Activation><Immunes><Immunity><Inequity><Infectious Diseases><Infectious Disorder><Institution><International><Intestinal Leakage><Investigation><LAV-HTLV-III><Leadership><Leaky Gut><Long-term infection><Lymphadenopathy-Associated Virus><Mediating><Mentors><Modeling><NIH><National Institutes of Health><Organ><Outcome><Ovarian><Ovocyclin><Ovocylin><P50 Mechanism><P50 Program><Pathogenesis><Pathology><Pathway interactions><Policies><Polishes><Position><Positioning Attribute><Probiotics><Progynon><Psychosocial Factor><Publications><R-Series Research Projects><R01 Mechanism><R01 Program><Reproducibility><Research><Research Grants><Research Infrastructure><Research Project Grants><Research Projects><Research Resources><Resources><Risk><Role><Science><Scientific Publication><Series><Sex Differences><Sexual differences><Sight><Specialized Center><Therapeutic Estradiol><Therapeutic Estrogen><Time><Training><United States National Institutes of Health><Universities><Virus-HIV><Vision><Woman><Women's Health><Work><Workshop><age associated comorbidities><at-risk females><at-risk women><biobehavior><biobehavioral><biological sex><biological sex as a modifier><bone><bone loss><career><career development><chronic infection><cohort><conference><convention><data management><decreased ovarian reserve><develop therapy><developmental><diets><differences in health><diminished ovarian reserve><dysbacteriosis><dysbiosis><dysbiotic><fecal microbial transplantation><fecal microbiome transplantation><fecal microbiota transplant><fecal microbiota transplantation><fecal transplant><fecal transplantation><females at high risk><health difference><high risk females><immune activation><immune reconstitution><improved><injury to organs><interdisciplinary collaboration><interest><intervention development><leadership development><microbial><microbial host><microbial imbalance><news><next generation><organ injury><pathogen><pathway><persistent infection><programs><psychosocial variables><response><sex><sex as a biological factor><sex as a biological measure><sex as a biological risk factor><sex as a biological variable><sex as a biological variance><sex as a biologically significant variable><sex as a fundamental variable><sex based differences><sex-dependent differences><sex-related differences><sex-specific differences><social factors><social role><summit><symposia><symposium><systemic inflammation><systemic inflammatory response><therapy development><transdisciplinary collaboration><treatment development><visual function><women at high risk>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Cathleen Noel Bairey Merz

CEDARS-SINAI MEDICAL CENTER, LOS ANGELES, CA

Exploratory lead · 42/100
Large award
Active award
Team-scale grant
$1,497,502
FY 2025

Project Title

The Microvascular Aging Effects - Women's Evaluation of Systemic aging Tenacity in Heart, Brain and Frailty (MAE-WEST HBF) ("You are never too old to become younger!")

Grant Number:

1U54AG094168-01

Activity Code:

U54

Mechanism:

Research Centers

Agency:

NIH

Start Date:

9/15/2025

End Date:

8/31/2030

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.

Project Abstract

PROJECT SUMMARY/ ABSTRACT- OVERALL The Microvascular Aging Effects – Women's Evaluation of Systemic aging Tenacity in Heart, Brain and Frailty (MAE-WEST HBF) (“You are never too old to become younger!”) Specialized Center of Research Excellence (SCORE) on Sex Differences, in response to NIH RFA-OD-2...

Research Terms

<AD related dementia><ADRD><Address><Affect><Aging><Alzheimer's and related dementias><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Amentia><Architecture><Biological Markers><Biopsy><Bleeding><Blood - brain barrier anatomy><Blood Vessels><Blood-Brain Barrier><Body Tissues><Brain><Brain Inflammation><Brain Nervous System><Brain Vascular Disorders><COBRE><Cardiology><Cardiovascular Diseases><Center of Biomedical Research Excellence><Centers of Research Excellence><Cerebral small vessel disease><Cerebrovascular Disease><Cerebrovascular Disorders><Cerebrovascular system><Chronic><Clinical><Clinical Sciences><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Coronary><Data><Dementia><Deposit><Deposition><Development><Diagnosis><Diastolic heart failure><Differences between sexes><Differs between sexes><Disease><Disorder><Disturbance in cognition><Drugs><Dysfunction><Eicosanoids><Encephalitis><Encephalon><Endothelium><Engineering / Architecture><Evaluation><Fe element><Female><Female Health><Fibrosis><Functional disorder><Future><Gait speed><Geriatrics><Goals><HF with preserved ejection fraction><HFpEF><Health><Heart><Heart Muscle tissue><Hemato-Encephalic Barrier><Hemorrhage><Human><Impaired cognition><Individual><Inflammation><Inflammatory><Infrastructure><Injury><Intervention><Intracranial Vascular Diseases><Intracranial Vascular Disorders><Investigation><Investigators><Iron><Ischemia><Kinesiology><Knowledge><LV remodeling><Left Ventricular Remodeling><Life Cycle><Life Cycle Stages><Link><MR Imaging><MR Tomography><MRI><MRIs><Magnetic Resonance Imaging><Measures><Mediating><Mediator><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Medication><Microvascular Dysfunction><Microvascular Permeability><Modern Man><Movement science><Muscle><Muscle Tissue><Myocardial><Myocardial tissue><NHLBI><NIH RFA><NMR Imaging><NMR Tomography><National Heart, Lung, and Blood Institute><Neurology><Nuclear Magnetic Resonance Imaging><Obstruction><Organ><Outcome><P50 Mechanism><P50 Program><Participant><Pathologist><Pathway interactions><Permeability><Persons><Pharmaceutical Preparations><Phenotype><Physical Function><Physiopathology><Pre-Clinical Model><Preclinical Models><Prevention><Preventive><Process><Property><Request for Applications><Research><Research Personnel><Research Resources><Researchers><Resources><Risk><Role><Scientist><Severities><Sex Differences><Sexual differences><Site><Skeletal Muscle><Specialized Center><Structure><Symptoms><Testing><Therapeutic><Tissues><Vascular Permeabilities><Voluntary Muscle><Woman><Women's Health><Work><Zeugmatography><age associated><age associated disease><age associated disorder><age associated effects><age associated impairment><age correlated><age dependent><age dependent disease><age dependent disorder><age dependent impairment><age effect><age linked><age related><age related effects><age related human disease><age specific><age-related disease><age-related disorder><age-related impairment><aging effect><bio-markers><biologic marker><biomarker><blood loss><blood vessels in the brain><bloodbrain barrier><brain Fe><brain blood vessels><brain iron><brain vascular disease><brain vascular dysfunction><brain vasculature><burden of disease><burden of illness><cardiovascular disorder><cerebral Fe><cerebral blood vessel><cerebral iron><cerebral small vessel disorder><cerebral vascular disease><cerebral vascular dysfunction><cerebral vasculature><cerebrovascular dysfunction><cerebrovascular vessels><cerebrovasculature><cognitive dysfunction><cognitive loss><cohort><computer based prediction><developmental><disease burden><drug/agent><experience><frailty><geriatric medicine><heart failure with preserved ejection fraction><heart failure with preserved systolic function><imaging scientist><impact of age><influence of age><injuries><injury to the vasculature><injury to tissue><innovate><innovation><innovative><insight><interest><intracranial vascular dysfunction><iron in the brain><left ventricle remodeling><life course><life span><lifespan><male><men><microvascular aging><microvascular complications><microvascular disease><muscular><novel><pathophysiology><pathway><predictive modeling><preserved ejection fraction heart failure><programs><prospective><response><sarcopenia><sarcopenic><sex based differences><sex-dependent differences><sex-related differences><sex-specific differences><small vessel disease><social role><therapeutic lifestyle change><tissue injury><translational investigator><translational researcher><translational scientist><vascular><vascular injury><♀><♂>
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Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

PAUL JOSEPH UTZ

STANFORD UNIVERSITY, STANFORD, CA

Exploratory lead · 42/100
Large award
Active award
Team-scale grant
$1,496,169
FY 2025

Project Title

Specialized Center of Research Excellence on Sex Differences in Autoimmunity

Grant Number:

1U54AR085970-01

Activity Code:

U54

Mechanism:

Research Centers

Agency:

NIH

Start Date:

9/1/2025

End Date:

5/31/2030

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.

Project Abstract

ComponentAutoimmune diseases comprise a large set of disorders that together afflict almost 50 million Americans; four out of five patients with autoimmunity are women. The mission of the Specialized Center of Research Excellence on Sex Differences in Autoimmunity (SCORE-X) is to serve as a national...

Research Terms

<Ab response><Affect><Age><American><Anti-Rejection Therapy><Antibodies><Antibody Formation><Antibody Production><Antibody Response><Antigens><Autoantibodies><Autoimmune Diseases><Autoimmune Status><Autoimmunity><Automobile Driving><B blood cells><B cell><B cells><B-Cells><B-Lymphocytes><B-cell><Biochemical><Biology><CD8 Cell><CD8 T cells><CD8 lymphocyte><CD8+ T cell><CD8+ T-Lymphocyte><CD8-Positive Lymphocytes><CD8-Positive T-Lymphocytes><COBRE><COVID-19><CV-19><Cancer Patient><Cell Body><Cells><Center of Biomedical Research Excellence><Centers of Research Excellence><Clinical><Complex><Coronavirus Infectious Disease 2019><Coupled><Diagnosis><Diagnostic><Differences between sexes><Differs between sexes><Disease><Disease Outcome><Disorder><Disproportionate number of females><Disproportionate number of women><Disproportionately affects females><Disproportionately affects women><Disproportionately impacts females><Disproportionately impacts women><Disproportionately in females><Disproportionately in women><Education><Education and Training><Educational aspects><Evaluation><Exhibits><Faculty><Feedback><Female><Female Roles><Functional RNA><Gender Bias><Gene Expression><Goals><Grant><Human><Immune><Immune Diseases><Immune Disorders><Immune Dysfunction><Immune System Diseases><Immune System Disorder><Immune System Dysfunction><Immune System and Related Disorders><Immune system><Immunes><Immunity><Immunologic Diseases><Immunological Diseases><Immunological Dysfunction><Immunological System Dysfunction><Immunosuppressive Therapy><In Vitro><Investigators><Knowledge><Leadership><Link><Lupus Erythematosus Disseminatus><Medicine><Mission><Modeling><Modern Man><Monitor><Non-Polyadenylated RNA><Noncoding RNA><Nontranslated RNA><Nuclear><Organoids><Outcome><P50 Mechanism><P50 Program><Patients><Pattern><Predictive Value><Production><Proteins><Proteomics><R-Series Research Projects><R01 Mechanism><R01 Program><RNA><RNA Gene Products><RNA-Binding Proteins><Regulator Genes><Research Grants><Research Personnel><Research Project Grants><Research Projects><Research Resources><Researchers><Resources><Ribonucleic Acid><Ribonucleoproteins><SLE><Sampling><Scleroderma><Sex Bias><Sex Differences><Sexual differences><Sicca Syndrome><Sight><Sjogren's Disease><Sjogren's Syndrome><Sjogrens><Sjögren Syndrome><Specialized Center><Survival Rate><Symptoms><Systemic Lupus Erythematosus><Systemic Lupus Erythematous><Systemic Lupus Erythmatosus><Systemic Scleroderma><Systemic Sclerosis><T8 Cells><T8 Lymphocytes><Technology><Testing><Therapeutic immunosuppression><Tonsil><Training><Training and Education><Transcriptional Regulatory Elements><Translations><Untranslated RNA><Validation><Vision><Woman><Women's Role><X Chromosome><advanced disease><advanced illness><ages><anti-cancer immunotherapy><antibody biosynthesis><anticancer immunotherapy><artificial immunosuppression><autoimmune antibody><autoimmune condition><autoimmune disorder><autoimmune reactivity><autoimmunity disease><autoreactive antibody><autoreactivity><biological sex as a modifier><cancer immunotherapy><career><cell type><clinical translation><clinically translatable><coronavirus disease 2019><coronavirus disease-19><coronavirus infectious disease-19><dermatosclerosis><diagnostic ability><diagnostic capability><diagnostic power><diagnostic utility><diagnostic value><disseminated lupus erythematosus><driving><education research><extracellular><female bias><female patients><female predominance><female preponderance><female sex hormone><genetic trans acting element><high school><human female><human tissue><immune-based cancer therapies><immunogen><immunogenic><immunoglobulin biosynthesis><immunosuppression therapy><immunotherapy for cancer><immunotherapy of cancer><improved><in vitro Model><innovate><innovation><innovative><insight><male><member><men><mouse model><multidisciplinary><murine model><noncoding><novel><patients being female><patients being women><patients who are female><predominance in females><predominance in women><prognostic><programs><progressive systemic sclerosis><protein complex><regulatory gene><response><scaffold><scaffolding><self reactive antibody><sex><sex as a biological factor><sex as a biological measure><sex as a biological risk factor><sex as a biological variable><sex as a biological variance><sex as a biologically significant variable><sex as a fundamental variable><sex based differences><sex-dependent differences><sex-related differences><sex-specific differences><systemic lupus erythematosis><tonsillar><trans acting element><translation><validations><visual function><women patients><women's predominance><women's preponderance><xerodermosteosis><♀><♂>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

AIMEE L MCRAE-CLARK

MEDICAL UNIVERSITY OF SOUTH CAROLINA, CHARLESTON, SC

Exploratory lead · 42/100
Large award
Active award
Team-scale grant
$1,495,542
FY 2025

Project Title

MUSC Specialized Center of Research Excellence on Sex Differences Renewal 2022

Grant Number:

5U54DA016511-23

Activity Code:

U54

Mechanism:

Research Centers

Agency:

NIH

Start Date:

9/1/2002

End Date:

7/31/2028

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.

Project Abstract

The MUSC Specialized Center of Research Excellence (SCORE) on Sex Differences in substance use disorders and the relationship between stress and relapse has been highly productive for 20 years. In addition to coalescing a multidisciplinary group of investigators across different disciplines working ...

Research Terms

<Acute><Address><Area><Behavioral><COBRE><Cannabis><Center of Biomedical Research Excellence><Centers of Research Excellence><Clinical><Clinical Research><Clinical Study><Collaborations><Communities><Data><Dedications><Differences between sexes><Differs between sexes><Discipline><Drug usage><Education and Outreach><Ensure><Faculty><Female Health><Fostering><Funding><Generalized Growth><Goals><Growth><Health><Institution><Instruction and Outreach><Interdisciplinary Research><Interdisciplinary Study><Investigators><Investments><Leadership><Mentors><Multidisciplinary Collaboration><Multidisciplinary Research><NIH><National Institutes of Health><Outcome><Output><P50 Mechanism><P50 Program><Pilot Projects><Population><Post-partum Women><Postpartum Women><Productivity><Public Health><R-Series Research Projects><R01 Mechanism><R01 Program><Relapse><Research><Research Grants><Research Institute><Research Personnel><Research Project Grants><Research Projects><Research Resources><Research Training><Researchers><Resources><SCTR><SCTR gene><Science><Secretin Receptor Gene><Services><Sex Differences><Sex Factors><Sexual differences><Sight><South Carolina><Specialized Center><Strategic Planning><Stress><Substance Use Disorder><THC co-use><THC use><Tetrahydrocannabinol co-use><Tetrahydrocannabinol use><Therapeutic><Tissue Growth><Training><Training and Outreach><Translational Research><Translational Research Enterprise><Translational Science><Translations><Tutoring and Outreach><United States National Institutes of Health><Universities><Vision><Woman><Women's Health><Work><addiction><addictive disorder><biological sex><cannabis use><cannabis use disorder><career><develop therapy><disparities in sex><drug use><early adulthood><emerging adult><improved><innovate><innovation><innovative><insight><intervention development><life span><lifespan><marijuana use><marijuana use and disorder><marijuana use disorder><multidisciplinary><neural circuit><neural circuitry><neurocircuitry><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><older adult><older adulthood><ontogeny><pilot study><programs><sex><sex based differences><sex disparity><sex-dependent differences><sex-related differences><sex-specific differences><skills><substance use><substance use and disorder><substance using><success><synaptic circuit><synaptic circuitry><therapy development><training opportunity><translation><translation research><translation research enterprise><translation strategy><translational approach><translational investigation><translational research program><translational strategy><treatment development><visual function>
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Rachel Lynn Tomko

MEDICAL UNIVERSITY OF SOUTH CAROLINA, CHARLESTON, SC

Exploratory lead · 42/100
Large award
Active award
Team-scale grant
$1,495,542
FY 2025

Project Title

MUSC Specialized Center of Research Excellence on Sex Differences Renewal 2022

Grant Number:

5U54DA016511-23

Activity Code:

U54

Mechanism:

Research Centers

Agency:

NIH

Start Date:

9/1/2002

End Date:

7/31/2028

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.

Project Abstract

The MUSC Specialized Center of Research Excellence (SCORE) on Sex Differences in substance use disorders and the relationship between stress and relapse has been highly productive for 20 years. In addition to coalescing a multidisciplinary group of investigators across different disciplines working ...

Research Terms

<Acute><Address><Area><Behavioral><COBRE><Cannabis><Center of Biomedical Research Excellence><Centers of Research Excellence><Clinical><Clinical Research><Clinical Study><Collaborations><Communities><Data><Dedications><Differences between sexes><Differs between sexes><Discipline><Drug usage><Education and Outreach><Ensure><Faculty><Female Health><Fostering><Funding><Generalized Growth><Goals><Growth><Health><Institution><Instruction and Outreach><Interdisciplinary Research><Interdisciplinary Study><Investigators><Investments><Leadership><Mentors><Multidisciplinary Collaboration><Multidisciplinary Research><NIH><National Institutes of Health><Outcome><Output><P50 Mechanism><P50 Program><Pilot Projects><Population><Post-partum Women><Postpartum Women><Productivity><Public Health><R-Series Research Projects><R01 Mechanism><R01 Program><Relapse><Research><Research Grants><Research Institute><Research Personnel><Research Project Grants><Research Projects><Research Resources><Research Training><Researchers><Resources><SCTR><SCTR gene><Science><Secretin Receptor Gene><Services><Sex Differences><Sex Factors><Sexual differences><Sight><South Carolina><Specialized Center><Strategic Planning><Stress><Substance Use Disorder><THC co-use><THC use><Tetrahydrocannabinol co-use><Tetrahydrocannabinol use><Therapeutic><Tissue Growth><Training><Training and Outreach><Translational Research><Translational Research Enterprise><Translational Science><Translations><Tutoring and Outreach><United States National Institutes of Health><Universities><Vision><Woman><Women's Health><Work><addiction><addictive disorder><biological sex><cannabis use><cannabis use disorder><career><develop therapy><disparities in sex><drug use><early adulthood><emerging adult><improved><innovate><innovation><innovative><insight><intervention development><life span><lifespan><marijuana use><marijuana use and disorder><marijuana use disorder><multidisciplinary><neural circuit><neural circuitry><neurocircuitry><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><older adult><older adulthood><ontogeny><pilot study><programs><sex><sex based differences><sex disparity><sex-dependent differences><sex-related differences><sex-specific differences><skills><substance use><substance use and disorder><substance using><success><synaptic circuit><synaptic circuitry><therapy development><training opportunity><translation><translation research><translation research enterprise><translation strategy><translational approach><translational investigation><translational research program><translational strategy><treatment development><visual function>
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Yong Li

BAYLOR COLLEGE OF MEDICINE, HOUSTON, TX

Exploratory lead · 42/100
Large award
Active award
Team-scale grant
$1,308,925
FY 2025

Project Title

Cancer Prevention-Interception Against MGUS Progression

Grant Number:

5U54CA272691-03

Activity Code:

U54

Mechanism:

Research Centers

Agency:

NIH

Start Date:

9/1/2023

End Date:

8/31/2027

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Project Summary Monoclonal gammopathy of undetermined significance (MGUS) is a precancerous condition in which a person has moderately elevated levels of an abnormal immunoglobulin (Ig) protein (called M protein) in the blood. MGUS patients have a cancer risk ~6.5 times as high as the control popula...

Research Terms

<19S Gamma Globulin><7S Gamma Globulin><Active Follow-up><Affect><Age Years><American><Amyloid><Amyloid Substance><Automobile Driving><B-Cell CLL><B-Cell Chronic Lymphocytic Leukemia><B-Cell Chronic Lymphogenous Leukemia><B-Cell Chronic Lymphoid Leukemia><B-Cell Lymphocytic Leukemia><B-Lymphocytic Leukemia><Blood><Blood Diseases><Blood Reticuloendothelial System><Bone Marrow><Bone Marrow Blood-Deriving Cell><Bone Marrow Blood-Forming Cell><Bone Marrow Cells><Bone Marrow Reticuloendothelial System><Cancer Center><Cancers><Chemicals><Chemoprevention><Chronic B-Lymphocytic Leukemia><Chronic Lymphatic Leukemia><Chronic Lymphoblastic Leukemia><Chronic Lymphocytic Leukemia><Chronic Lymphogenous Leukemia><Communication><Consensus><DNA Vaccines><Dedications><Development><Development and Research><Diagnosis><Diagnostic><Disease><Disorder><E3 Ligase><E3 Ubiquitin Ligase><Funding><Ganciclovir><Gancyclovir><Goals><Hematologic Diseases><Hematological Disease><Hematological Disorder><IgA><IgD><IgE><IgG><IgM><Immune Globulins><Immunochemical Immunologic><Immunoglobulin A><Immunoglobulin D><Immunoglobulin E><Immunoglobulin G><Immunoglobulin M><Immunoglobulins><Immunologic><Immunological><Immunologically><Immunologics><Immunoprevention><In Vitro><Infrastructure><Intercept><Intervention><Intervention Strategies><Investigation><Investigators><Life Expectancy><Light><Light-Chain Immunoglobulins><Lymphoid><Lymphoplasmacytic Lymphoma><Lymphoplasmacytic Lymphoma/Waldenstrom's Macroglobulinemia><Lymphoplasmacytic Type Immunocytoma><Lymphoplasmacytoid Lymphoma><M protein><MGUS><Macroglobulinemia><Malignant Neoplasms><Malignant Tumor><Molecular><Monoclonal Gammopathy of Undetermined Significance><Monoclonal Gammopathy of Unknown Significance><Monoclonal gammopathy of uncertain significance><Multiple Myeloma><Mutate><Naked DNA Vaccines><Network Infrastructure><Non-Hodgkin's Lymphoma><Nonhodgkins Lymphoma><Nordeoxyguanosine><Oncogene Products><Oncogene Proteins><Oncogenic><Oncoproteins><P50 Mechanism><P50 Program><Patients><Persons><Photoradiation><Plasma-Cell Myeloma><Plasmacytoma><Population><Population Control><Precancerous Conditions><Premalignant Condition><Premalignant State><Prevention><Preventive><Process><Protein Secretion><Proteins><R & D><R&D><R-Series Research Projects><R01 Mechanism><R01 Program><Recombinant DNA Vaccines><Recommendation><Research><Research Grants><Research Personnel><Research Project Grants><Research Projects><Researchers><Risk><Risk Factors><Role><Solitary Plasmacytoma><Specialized Center><Syndrome><Testing><Ubiquitin Protein Ligase><Ubiquitin-Protein Ligase Complexes><Ubiquitin-Protein Ligase E3><Waldenstrom Macroglobulinemia><Waldenstrom's macroglobulinaemia><Waldenström's hyperglobulinaemia><Waldenström's hyperglobulinemia><Waldenström's macroglobulinaemia><Waldenström's macroglobulinemia><active followup><blood disorder><cancer diagnosis><cancer invasiveness><cancer prevention><cancer progression><cancer risk><chronic lymphoid leukemia><clinical practice><determine efficacy><developmental><driving><early clinical trial><early phase clinical trial><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><evaluate efficacy><examine efficacy><follow up><follow-up><followed up><followup><high risk><in vivo><individualized cancer care><individualized oncology><innovate><innovation><innovative><light chain amyloidosis><malignancy><multiple myeloma M Protein><myeloma><myelomatosis><neoplasm progression><neoplasm/cancer><neoplastic progression><non-Hodgkins disease><novel><personalized oncology><precancerous state><precision cancer care><precision cancer medicine><precision cancer prevention><precision oncology><prevent><preventing><primary amyloidosis of light chain type><programs><progression risk><research and development><senescence><senescent><small molecule><social role><targeted agent><tumor initiation><tumor progression><ubiquitin-protein ligase>
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KC KENT LLOYD

UNIVERSITY OF CALIFORNIA AT DAVIS, DAVIS, CA

Exploratory lead · 42/100
Above-average budget
Active award
Team-scale grant
$764,750
FY 2026

Project Title

The National Center for Metabolic Phenotyping of Mouse Models of Obesity and Diabetes (MPMOD) at UC Davis

Grant Number:

5U2CDK135074-04

Activity Code:

U2C

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

2/1/2023

End Date:

1/31/2028

Why this may be worth a closer look

  • • Award size is strong enough to merit immediate review.

Project Abstract

Enter the text here that is the new abstract information for your application. This section must be no longer than 30 lines of text. Translational research in vivo using genetic, surgical, humanized, and other types of mouse models are needed to decipher the heterogeneity of diabetes, obesity, and ...

Research Terms

<Address><Animals><Anxiety><Awareness><Behavior><Bioenergetics><Biomedical Research><Body Composition><Body Temperature Regulation><Body Thermoregulation><Caloric Intake><Cardiovascular><Cardiovascular Body System><Cardiovascular Organ System><Cardiovascular system><Causality><Client><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive function abnormal><Communities><Complex><Consultations><Continuous Glucose Monitor><Data Analyses><Data Analysis><Development><Diabetes Mellitus><Diabetic mouse><Diagnostic><Disease><Disorder><Disturbance in cognition><Dysfunction><Eating><Economic Income><Economical Income><Education and Training><Energy Expenditure><Energy Intake><Energy Metabolism><Etiology><Evaluation><Exercise><Experimental Designs><Fee-for-Service Plans><Feeding behaviors><Fees for Service><Food Intake><Functional disorder><Genetic><Goals><Grant><Health><Heart Vascular><Heterogeneity><Human><Image><Impaired cognition><In vivo analysis><Income><Infrastructure><Ingestive Behavior><Institution><Intermediary Metabolism><Investigators><Investments><Kidney><Kidney Urinary System><Learning><Macronutrients><Macronutrients Nutrition><Measures><Memory><Mental Depression><Metabolic><Metabolic Diseases><Metabolic Disorder><Metabolic Processes><Metabolism><Mice><Mice Mammals><Modeling><Modern Man><Motor><Murine><Mus><Mutant Strains Mice><Neurologic><Neurological><Obesity><Operative Procedures><Operative Surgical Procedures><Organ><Outcome Measure><P50 Mechanism><P50 Program><PET><PET Scan><PET imaging><PETSCAN><PETT><Pathogenesis><Phenotype><Physiologic><Physiologic Thermoregulation><Physiological><Physiology><Physiopathology><Positron Emission Tomography Medical Imaging><Positron Emission Tomography Scan><Positron-Emission Tomography><Preventative strategy><Prevention><Prevention strategy><Preventive strategy><Procedures><Protocol><Protocols documentation><Rad.-PET><Recommendation><Reproducibility><Research><Research Activity><Research Personnel><Research Resources><Researchers><Resources><Role><Scientist><Services><Sleep><Specialist><Specialized Center><Stress><Surgical><Surgical Interventions><Surgical Procedure><Technology><Testing><Text><Therapeutic><Thermoregulation><Thesaurismosis><Training and Education><Translating><Translational Research><Translational Science><adiposity><animal care><bariatric surgery><behavior phenotype><behavior test><behavioral phenotyping><behavioral test><caloric dietary content><causation><circulatory system><clinical relevance><clinically relevant><cognitive dysfunction><cognitive loss><consultation><continuous blood glucose monitor><continuous blood sugar monitor><continuous glucose measurement><continuous sugar monitor><corpulence><cost><data interpretation><depository><depression><developmental><diabetes><diabetes mouse model><disease causation><disease diagnosis><energy balance><experience><experiment><experimental research><experimental study><experiments><feeding-related behaviors><gastric banding><gastric bypass surgery><gastrointestinal><imaging><imaging capabilities><implantable gastric stimulation banding><improved><in vivo><in vivo evaluation><in vivo testing><incomes><innovate><innovation><innovative><instrument><measurable outcome><metabolic phenotype><metabolism disorder><metabotype><microbiome><mouse model><mouse mutant><murine model><neurobehavioral><neurophysiological><neurophysiology><novel><nutrient intake activity><obesity surgery><operation><operations><outcome measurement><outreach><pathophysiology><patient population><positron emission tomographic (PET) imaging><positron emission tomographic imaging><positron emitting tomography><programs><renal><repository><respiratory><response><social role><stomach stapling><surgery><training opportunity><translation research><translational investigation><web site><website><weight loss surgery>
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Eric Dinesh Shah

UNIVERSITY OF MICHIGAN AT ANN ARBOR, ANN ARBOR, MI

Exploratory lead · 42/100
Training-friendly
Active award
Career award
$194,400
FY 2026

Project Title

Guideline to Implementation: A Rapid Clinical Care Pathway to Care for Patients Affected by Chronic Constipation

Grant Number:

5K23DK134752-04

Activity Code:

K23

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

5/15/2023

End Date:

1/31/2028

Why this may be worth a closer look

  • • Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT SUMMARY Technology development is a stated goal of the NIH. Myriad promising technologies have been developed, yet few cross the chasm to adoption. Few NIH-funded researchers are trained to develop and sustain transformative clinical care pathways that harness novel, evidence-based technolo...

Research Terms

<Academic Medical Centers><Adoption><Affect><Automobile Driving><Caring><Chronic><Chronic Care><Clinic><Clinical><Colonoscopy><Community Practice><Constipation><Consultations><Data><Devices><Diagnostic Device><Diagnostic Equipment><Diagnostic Method><Diagnostic Procedure><Diagnostic Technique><Disease><Disorder><Effectiveness><Electronic Health Record><Endoscopy><Fiber><Funding><Gastroenterologist><Gastroenterology><Gastrointestinal Motility><Goals><Grant><Guidelines><Health><Health system><Image><Impairment><Improve Access><Intake><Intervention><Investigators><Laxative Preparation><Medical><Medical Rehabilitation><Motility><Multi-center trial><Multicenter Trials><NIH><National Institutes of Health><Needs Assessment><Out-patients><Outpatients><P50 Mechanism><P50 Program><Pathway interactions><Patient Care><Patient Care Delivery><Patient Triage><Patients><Pelvic><Pelvic Floor><Pelvic Region><Pelvic floor structure><Pelvis><Physiatric Procedure><Physical Medicine Procedure><Physical Therapeutics><Physical therapy><Physiologic><Physiological><Physiotherapy><Point of Care Technology><Population><Position><Positioning Attribute><Positive Reinforcements><Practice Guidelines><Prediction of Response to Therapy><Process><Production><Provider><QOL><QOL improvement><Quality of life><Questionnaires><Randomization trial><Recommendation><Rectum><Refractory><Rehabilitation><Rehabilitation therapy><Research><Research Personnel><Researchers><Rotation><Specialized Center><Specialty><Symptoms><Technology><Testing><Training><Treatment outcome><Triage><United States National Institutes of Health><University Medical Centers><Visit><Work><adoption by clinician><adoption by health care providers><adoption by physician><adoption by provider><behavioral economics><care as usual><care for patients><care of patients><career><caring for patients><clinical care><clinical decision support><clinical practice><clinician adoption><clinician behavior><consultation><cost><design><designing><diagnostic technologies><driving><dysmotility><dysmotility syndrome><effective therapy><effective treatment><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><endoscopic imaging><evidence base><health and care delivery><health care delivery><health delivery systems><health services delivery><imaging><implementation science><implementation trial><improved><improvements in QOL><improvements in quality of life><laxative><learned behavior><learning behavior><medical specialties><motility disorder><novel><pathway><patient population><physical therapist><physician adoption><physician behavior><physiotherapist><pilot trial><point of care><point-of-care diagnostics><practice setting><predict therapeutic response><predict therapy response><prospective><provider adoption><provider behavior><provider-level adoption><quality of life improvement><randomized trial><rehab therapy><rehabilitative><rehabilitative therapy><response><routine care><success><support tools><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment><tech development><technology development><tertiary care><therapy prediction><treatment as usual><treatment prediction><treatment response prediction><usability><user centered design><usual care>
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Matthew K Abramowitz

ALBERT EINSTEIN COLLEGE OF MEDICINE, BRONX, NY

Exploratory lead · 40/100
Above-average budget
Recent
Active award
$556,651
FY 2026

Project Title

Scalable imaging approach to measure muscle bioenergetics in CKD.

Grant Number:

1R21AR087144-01

Activity Code:

R21

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/4/2026

End Date:

2/29/2028

Why this may be worth a closer look

  • • Award size is strong enough to merit immediate review.

Project Abstract

Project Summary/Abstract Skeletal muscle dysfunction causes frailty and disability in patients with chronic kidney disease (CKD) and contributes to their extremely high rates of mortality. A major contributor to poor muscle function in CKD is mitochondrial dysfunction; thus, the ability to identify ...

Research Terms

<21+ years old><Accounting><Address><Adipose tissue><Adult><Adult Human><Affect><Age><Aging><Anatomic Sites><Anatomic structures><Anatomy><Area><Atrophic><Atrophy><Biochemical><Bioenergetics><Biopsy><Blood Vessels><Chemical Dynamics><Chemicals><Chronic Disease><Chronic Illness><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Clinical><Creatine><Creatine Phosphate><Data><Death Rate><Dedications><Development><Dysfunction><Equilibrium><Exercise><Fats><Fatty Tissue><Fatty acid glycerol esters><Fibrosis><Fostering><Functional disorder><Funding><Future><Generations><Health><Heterogeneity><Histologic><Histologically><Impairment><Infiltration><Intervention><Intramuscular><Investigation><Knowledge><Link><MR Imaging><MR Spectroscopy><MR Tomography><MRI><MRI Scans><MRIs><Magnetic Resonance Imaging><Magnetic Resonance Imaging Scan><Magnetic Resonance Spectroscopy><Maps><Measurement><Measures><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Methods><Mitochondria><Modeling><Molecular><Multi-Institutional Clinical Trial><Multi-center clinical trial><Multi-center trial><Multi-site clinical trial><Multicenter Trials><Multicenter clinical trial><Multisite clinical trial><Muscle><Muscle Disease><Muscle Disorders><Muscle Mitochondria><Muscle Tissue><Muscle function><Muscular Diseases><Myopathic Conditions><Myopathic Diseases and Syndromes><Myopathic disease or syndrome><Myopathy><NMR Imaging><NMR Tomography><Nuclear Magnetic Resonance Imaging><O element><O2 element><Oxygen><P50 Mechanism><P50 Program><Parents><Participant><Pathology><Patients><Phenotype><Phosphocreatine><Phosphorylation><Phosphorylcreatine><Physical Function><Physical Performance><Physics><Physiopathology><Prospective, cohort study><Protein Phosphorylation><Protocol><Protocols documentation><Recovery><Renal function><Research><Research Resources><Resolution><Resources><Rest><Sarcosomes><Severities><Skeletal Muscle><Specialized Center><Testing><Time><Translating><Variant><Variation><Voluntary Muscle><Walking><Zeugmatography><adipose><adulthood><ages><balance><balance function><chronic disorder><chronic kidney disease><clinical phenotype><clinical practice><cohort><cohort investigation><cohort research><decline in function><decline in functional status><developmental><disability><early biomarkers><early detection biomarkers><early detection markers><efficacy testing><exercise intervention><frailty><functional decline><functional status decline><image-based method><imaging approach><imaging based approach><imaging method><imaging modality><in vivo><innovate><innovation><innovative><innovative technologies><insight><investigate cohort><kidney function><mitochondrial><mitochondrial dysfunction><mortality rate><muscular><muscular disorder><neglect><new approaches><novel><novel approaches><novel strategies><novel strategy><parent><pathophysiology><physical activity intervention><physical impairment><pre-clinical><preclinical><primary outcome><prognostic><resolutions><secondary outcome><sex><study cohort><survey cohort><vascular><vastus lateralis><white adipose tissue><yellow adipose tissue>
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Camille C Cioffi

UNIVERSITY OF OREGON, EUGENE, OR

Exploratory lead · 40/100
Solid budget
Very recent
Active award
$469,204
FY 2026

Project Title

A Patient Engagement Resource Center using Community-Based Participatory Action Research to Support Parents with Substance Use Disorders

Grant Number:

5R24DA061209-03

Activity Code:

R24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

7/1/2024

End Date:

4/30/2029

Why this may be worth a closer look

  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

7. Project Summary Most people with substance use disorders (SUD) are parents (i.e., pregnant, postpartum, parenting). However, parents with SUD receive little focused attention as it pertains to treatment services tailored to their needs as a parent. Becoming a parent is lifechanging regardless of ...

Research Terms

<0-11 years old><6 year old><6 years of age><Abscission><Address><Area><Attention><Benchmarking><Best Practice Analysis><Birth><Cannot see a future><Caring><Child><Child Care><Child Rearing><Child Youth><Children (0-21)><Clinic><Cognitive Discrimination><Collaborations><Communities><Consultations><Data><Data Bases><Databases><Decision Making><Dedications><Discrimination><Disparities><Disparity><Documentation><Ethnic Origin><Ethnicity><Evaluation><Excision><Extirpation><Face><Family><Fear><Feeling hopeless><Feels there is no future><Fright><Future><Gender><Gestation><Goals><Grief><Grief reaction><Individual><Infant><Infrastructure><Investigators><Lead><Life><Lived experience><Lived experiences><Loss of hope for the future><Modeling><Mothers><Motivation><NIDA><National Institute of Drug Abuse><National Institute on Drug Abuse><Negative about the future><No hope for the future><Opiates><Opioid><Outcome><Parenting><Parenting behavior><Parents><Participant><Parturition><Pb element><Perception><Persons><Pilot Projects><Population><Postpartum Period><Pregnancy><Procedures><Process><Puericulture><R-Series Research Projects><R01 Mechanism><R01 Program><Race><Races><Recovery><Removal><Reporting><Research><Research Design><Research Ethics><Research Grants><Research Methodology><Research Methods><Research Personnel><Research Priority><Research Project Grants><Research Projects><Research Resources><Researchers><Resources><Safety><Science><Shame><Study Type><Substance Use Disorder><Surgical Removal><Training><Translational Research><Translational Science><Treatment outcome><Work><age 6><age 6 years><barrier to care><barrier to health care><barrier to treatment><benchmark><childrearing><community based participatory research><community led research><community participatory research><community partnered participatory research><consultation><data base><disenfranchised group><disenfranchised individual><disenfranchised people><disenfranchised population><disparities in treatment><effectiveness research><experience><experienced discrimination><faces><facial><heavy metal Pb><heavy metal lead><hopelessness><improved><improved outcome><inequality in treatment><innovate><innovation><innovative><internalized stigma><kids><member><obstacle to care><obstacle to health care><parent><parent role><parental role><participant engagement><participatory action research><patient engagement><perceived discrimination><perception of discrimination><person centered><pilot study><post-partum><pregnant><programs><racial><racial background><racial origin><recruit><research and methods><research data dissemination><research dissemination><research study><resection><return to use><rurality><self-reported discrimination><self-stigma><six year old><six years of age><social health determinants><social stigma><stigma><study design><substance use and disorder><substance use treatment><success><sustained recovery><translation research><translational investigation><treatment disparity><treatment inequality><treatment inequity><treatment services><willingness><youngster>
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Leslie Diane Leve

UNIVERSITY OF OREGON, EUGENE, OR

Exploratory lead · 40/100
Solid budget
Very recent
Active award
$469,204
FY 2026

Project Title

A Patient Engagement Resource Center using Community-Based Participatory Action Research to Support Parents with Substance Use Disorders

Grant Number:

5R24DA061209-03

Activity Code:

R24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

7/1/2024

End Date:

4/30/2029

Why this may be worth a closer look

  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

7. Project Summary Most people with substance use disorders (SUD) are parents (i.e., pregnant, postpartum, parenting). However, parents with SUD receive little focused attention as it pertains to treatment services tailored to their needs as a parent. Becoming a parent is lifechanging regardless of ...

Research Terms

<0-11 years old><6 year old><6 years of age><Abscission><Address><Area><Attention><Benchmarking><Best Practice Analysis><Birth><Cannot see a future><Caring><Child><Child Care><Child Rearing><Child Youth><Children (0-21)><Clinic><Cognitive Discrimination><Collaborations><Communities><Consultations><Data><Data Bases><Databases><Decision Making><Dedications><Discrimination><Disparities><Disparity><Documentation><Ethnic Origin><Ethnicity><Evaluation><Excision><Extirpation><Face><Family><Fear><Feeling hopeless><Feels there is no future><Fright><Future><Gender><Gestation><Goals><Grief><Grief reaction><Individual><Infant><Infrastructure><Investigators><Lead><Life><Lived experience><Lived experiences><Loss of hope for the future><Modeling><Mothers><Motivation><NIDA><National Institute of Drug Abuse><National Institute on Drug Abuse><Negative about the future><No hope for the future><Opiates><Opioid><Outcome><Parenting><Parenting behavior><Parents><Participant><Parturition><Pb element><Perception><Persons><Pilot Projects><Population><Postpartum Period><Pregnancy><Procedures><Process><Puericulture><R-Series Research Projects><R01 Mechanism><R01 Program><Race><Races><Recovery><Removal><Reporting><Research><Research Design><Research Ethics><Research Grants><Research Methodology><Research Methods><Research Personnel><Research Priority><Research Project Grants><Research Projects><Research Resources><Researchers><Resources><Safety><Science><Shame><Study Type><Substance Use Disorder><Surgical Removal><Training><Translational Research><Translational Science><Treatment outcome><Work><age 6><age 6 years><barrier to care><barrier to health care><barrier to treatment><benchmark><childrearing><community based participatory research><community led research><community participatory research><community partnered participatory research><consultation><data base><disenfranchised group><disenfranchised individual><disenfranchised people><disenfranchised population><disparities in treatment><effectiveness research><experience><experienced discrimination><faces><facial><heavy metal Pb><heavy metal lead><hopelessness><improved><improved outcome><inequality in treatment><innovate><innovation><innovative><internalized stigma><kids><member><obstacle to care><obstacle to health care><parent><parent role><parental role><participant engagement><participatory action research><patient engagement><perceived discrimination><perception of discrimination><person centered><pilot study><post-partum><pregnant><programs><racial><racial background><racial origin><recruit><research and methods><research data dissemination><research dissemination><research study><resection><return to use><rurality><self-reported discrimination><self-stigma><six year old><six years of age><social health determinants><social stigma><stigma><study design><substance use and disorder><substance use treatment><success><sustained recovery><translation research><translational investigation><treatment disparity><treatment inequality><treatment inequity><treatment services><willingness><youngster>
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STEVEN C. ALMO

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

Exploratory lead · 40/100
Solid budget
Very recent
Active award
$254,529
FY 2026

Project Title

A Multifunctional Biologic to Regulate Transplant Rejection

Grant Number:

1R21AI199177-01

Activity Code:

R21

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/5/2026

End Date:

4/30/2028

Why this may be worth a closer look

  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary/Abstract Solid organ transplantation remains the definitive treatment for end-stage organ failure, but is limited by the adverse effects of lifelong immunosuppression and the risk of chronic rejection. Blockade of the CD154/CD40 costimulatory pathway has shown unparalleled efficacy i...

Research Terms

<Address><Adoptive Transfer><Adverse effects><Affinity><Architecture><Assay><Bioassay><Biological><Biological Assay><Biological Response Modifier Therapy><Biological Therapy><Biomedical Research><Bone-Derived Transforming Growth Factor><Bp50><CD154><CD40><CD40L><CD40LG><CDW40><Cell Body><Cell Count><Cell Differentiation><Cell Differentiation process><Cell Number><Cells><Chimera Protein><Chimeric Proteins><Chronic><Clinical assessments><Co-Stimulator><Complex><Costimulator><Data><Dermatoplasties><Dermatoplasty><Development><Disease><Disorder><Dose><Drug Kinetics><Effector Cell><Engineering><Engineering / Architecture><Ensure><Epidermal Thymocyte Activating Factor><FOXP3><FOXP3 gene><Face><Forkhead Box P3><Fusion Protein><Future><Graft Rejection><Graft Survival><Grafting Procedure><Health><Human><IL-2><IL2 Protein><Immune><Immune Targeting><Immunes><Immunochemical Immunologic><Immunologic><Immunological><Immunologically><Immunologics><Immunomodulation><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><Immunotherapeutic agent><In Vitro><In vivo analysis><Interdisciplinary Research><Interdisciplinary Study><Interleukin 2><Interleukin 2 Precursor><Interleukin II><Interleukin-2><Interleukine 2><Interleukine 2 Precursor><Interleukine II><JM2><Knowledge><Lead><Lymphocyte Mitogenic Factor><MGC9013><Mediating><Mice><Mice Mammals><Milk Growth Factor><Mission><Mitogenic Factor><Modern Man><Multidisciplinary Collaboration><Multidisciplinary Research><Murine><Mus><NIH><National Institutes of Health><Organ Transplantation><Organ Transplants><Outcome><Pathogenicity><Pathologic><Pathway interactions><Pb element><Pharmacokinetics><Platelet Transforming Growth Factor><Pre-Clinical Model><Preclinical Models><Protein Engineering><Receptor Protein><Recombinants><Regulation><Regulatory T-Lymphocyte><Research><Research Design><Risk><SCURFIN><Scaffolding Protein><Signal Pathway><Skin Transplantation><Solid><Study Type><System><T cell based immune therapy><T cell based therapeutics><T cell based therapy><T cell differentiation><T cell directed therapies><T cell growth factor><T cell immune therapy><T cell immunotherapy><T cell response><T cell targeted therapeutics><T cell therapy><T cell treatment><T cell-based immunotherapy><T cell-based treatment><T cellular immunotherapy><T cellular therapy><T lymphocyte based immunotherapy><T lymphocyte based therapy><T lymphocyte therapeutic><T lymphocyte treatment><T-Cell Growth Factor><T-Cell Stimulating Factor><T-Cells><T-Lymphocyte><T-cell therapeutics><T-cell transfer therapy><TGF B><TGF-beta><TGF-β><TGFbeta><TGFβ><TNFRSF5><TNFRSF5 gene><TNFSF5><TNFSF5 gene><TRAP Gene><Teff cell><Therapeutic><Therapeutic Effect><Thymocyte Stimulating Factor><Toxic effect><Toxicities><Transforming Growth Factor beta><Transforming Growth Factor-Beta Family Gene><Transfusion><Transgenic Organisms><Translating><Translations><Transplant Recipients><Transplant Rejection><Transplantation><Transplantation Rejection><Transplantation Tolerance><Treatment Efficacy><Treg><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><United States National Institutes of Health><Validation><Variant><Variation><adoptive T cell transfer><adoptive T lymphocyte transfer><adoptive T-cell therapy><biologic><biological therapeutic><biological treatment><biologically based therapeutics><biotherapeutics><biotherapy><cellular differentiation><clinical applicability><clinical application><clinical development><clinical translation><clinically translatable><cost><cost effective><cross reactivity><design><designing><developmental><effective therapy><effective treatment><effector T cell><end-stage organ failure><faces><facial><genetic protein engineering><heavy metal Pb><heavy metal lead><high reward><high risk><immune drugs><immune modulation><immune regulation><immune suppression><immune suppressive activity><immune suppressive function><immune-based therapeutics><immunologic reactivity control><immunologic therapeutics><immunomodulatory><immunoregulation><immunoregulatory><immunosuppressive activity><immunosuppressive function><immunosuppressive response><immunotherapeutics><immunotherapy agent><improved><in vivo evaluation><in vivo testing><inflammatory environment><inflammatory milieu><innovate><innovation><innovative><interdisciplinary approach><interdisciplinary collaboration><intervention efficacy><multi-component intervention><multi-faceted intervention><multi-modal intervention><multicomponent intervention><multidisciplinary approach><multifaceted intervention><multimodal intervention><next generation><novel><organ allograft><organ graft><organ xenograft><p50><pathway><pre-clinical><preclinical><programs><protein design><receptor><regulatory T-cells><safety assessment><side effect><study design><success><synergism><systemic toxicity><therapeutic T-cell platform><therapeutic efficacy><therapeutic evaluation><therapeutic testing><therapy efficacy><thymus derived lymphocyte><transdisciplinary collaboration><transgenic><translatable strategy><translation><transplant><transplant model><transplant patient><treatment strategy><validations>
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Giorgio Raimondi

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

Exploratory lead · 40/100
Solid budget
Very recent
Active award
$254,529
FY 2026

Project Title

A Multifunctional Biologic to Regulate Transplant Rejection

Grant Number:

1R21AI199177-01

Activity Code:

R21

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

5/5/2026

End Date:

4/30/2028

Why this may be worth a closer look

  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary/Abstract Solid organ transplantation remains the definitive treatment for end-stage organ failure, but is limited by the adverse effects of lifelong immunosuppression and the risk of chronic rejection. Blockade of the CD154/CD40 costimulatory pathway has shown unparalleled efficacy i...

Research Terms

<Address><Adoptive Transfer><Adverse effects><Affinity><Architecture><Assay><Bioassay><Biological><Biological Assay><Biological Response Modifier Therapy><Biological Therapy><Biomedical Research><Bone-Derived Transforming Growth Factor><Bp50><CD154><CD40><CD40L><CD40LG><CDW40><Cell Body><Cell Count><Cell Differentiation><Cell Differentiation process><Cell Number><Cells><Chimera Protein><Chimeric Proteins><Chronic><Clinical assessments><Co-Stimulator><Complex><Costimulator><Data><Dermatoplasties><Dermatoplasty><Development><Disease><Disorder><Dose><Drug Kinetics><Effector Cell><Engineering><Engineering / Architecture><Ensure><Epidermal Thymocyte Activating Factor><FOXP3><FOXP3 gene><Face><Forkhead Box P3><Fusion Protein><Future><Graft Rejection><Graft Survival><Grafting Procedure><Health><Human><IL-2><IL2 Protein><Immune><Immune Targeting><Immunes><Immunochemical Immunologic><Immunologic><Immunological><Immunologically><Immunologics><Immunomodulation><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><Immunotherapeutic agent><In Vitro><In vivo analysis><Interdisciplinary Research><Interdisciplinary Study><Interleukin 2><Interleukin 2 Precursor><Interleukin II><Interleukin-2><Interleukine 2><Interleukine 2 Precursor><Interleukine II><JM2><Knowledge><Lead><Lymphocyte Mitogenic Factor><MGC9013><Mediating><Mice><Mice Mammals><Milk Growth Factor><Mission><Mitogenic Factor><Modern Man><Multidisciplinary Collaboration><Multidisciplinary Research><Murine><Mus><NIH><National Institutes of Health><Organ Transplantation><Organ Transplants><Outcome><Pathogenicity><Pathologic><Pathway interactions><Pb element><Pharmacokinetics><Platelet Transforming Growth Factor><Pre-Clinical Model><Preclinical Models><Protein Engineering><Receptor Protein><Recombinants><Regulation><Regulatory T-Lymphocyte><Research><Research Design><Risk><SCURFIN><Scaffolding Protein><Signal Pathway><Skin Transplantation><Solid><Study Type><System><T cell based immune therapy><T cell based therapeutics><T cell based therapy><T cell differentiation><T cell directed therapies><T cell growth factor><T cell immune therapy><T cell immunotherapy><T cell response><T cell targeted therapeutics><T cell therapy><T cell treatment><T cell-based immunotherapy><T cell-based treatment><T cellular immunotherapy><T cellular therapy><T lymphocyte based immunotherapy><T lymphocyte based therapy><T lymphocyte therapeutic><T lymphocyte treatment><T-Cell Growth Factor><T-Cell Stimulating Factor><T-Cells><T-Lymphocyte><T-cell therapeutics><T-cell transfer therapy><TGF B><TGF-beta><TGF-β><TGFbeta><TGFβ><TNFRSF5><TNFRSF5 gene><TNFSF5><TNFSF5 gene><TRAP Gene><Teff cell><Therapeutic><Therapeutic Effect><Thymocyte Stimulating Factor><Toxic effect><Toxicities><Transforming Growth Factor beta><Transforming Growth Factor-Beta Family Gene><Transfusion><Transgenic Organisms><Translating><Translations><Transplant Recipients><Transplant Rejection><Transplantation><Transplantation Rejection><Transplantation Tolerance><Treatment Efficacy><Treg><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><United States National Institutes of Health><Validation><Variant><Variation><adoptive T cell transfer><adoptive T lymphocyte transfer><adoptive T-cell therapy><biologic><biological therapeutic><biological treatment><biologically based therapeutics><biotherapeutics><biotherapy><cellular differentiation><clinical applicability><clinical application><clinical development><clinical translation><clinically translatable><cost><cost effective><cross reactivity><design><designing><developmental><effective therapy><effective treatment><effector T cell><end-stage organ failure><faces><facial><genetic protein engineering><heavy metal Pb><heavy metal lead><high reward><high risk><immune drugs><immune modulation><immune regulation><immune suppression><immune suppressive activity><immune suppressive function><immune-based therapeutics><immunologic reactivity control><immunologic therapeutics><immunomodulatory><immunoregulation><immunoregulatory><immunosuppressive activity><immunosuppressive function><immunosuppressive response><immunotherapeutics><immunotherapy agent><improved><in vivo evaluation><in vivo testing><inflammatory environment><inflammatory milieu><innovate><innovation><innovative><interdisciplinary approach><interdisciplinary collaboration><intervention efficacy><multi-component intervention><multi-faceted intervention><multi-modal intervention><multicomponent intervention><multidisciplinary approach><multifaceted intervention><multimodal intervention><next generation><novel><organ allograft><organ graft><organ xenograft><p50><pathway><pre-clinical><preclinical><programs><protein design><receptor><regulatory T-cells><safety assessment><side effect><study design><success><synergism><systemic toxicity><therapeutic T-cell platform><therapeutic efficacy><therapeutic evaluation><therapeutic testing><therapy efficacy><thymus derived lymphocyte><transdisciplinary collaboration><transgenic><translatable strategy><translation><transplant><transplant model><transplant patient><treatment strategy><validations>
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Nicholas Daniel Carey

UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, SAN FRANCISCO, CA

Exploratory lead · 40/100
Training-friendly
Recent
Active award
$48,343
FY 2026

Project Title

Hepatic Priming of CD4+ T cells Directs Effective Hepatitis B Virus Immunity

Grant Number:

5F31DK135386-03

Activity Code:

F31

Mechanism:

Training, Individual

Agency:

NIH

Start Date:

3/15/2024

End Date:

3/14/2027

Why this may be worth a closer look

  • • Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT SUMMARY/ABSTRACT Chronic infection with hepatitis B virus (HBV) is a leading global cause of end-stage liver disease and hepatocellular carcinoma; fatal outcomes that can be prevented when serum hepatitis B surface antigen (HBsAg) clearance is achieved, which rarely occurs with available tr...

Research Terms

<0-11 years old><21+ years old><Acute><Acute Hepatitis><Adult><Adult Human><Age><Agonist><Anti-viral Therapy><Antibodies><Antigen Presentation><Antigen-Presenting Cells><Antigens><Assay><Attenuated><Au antigen><Australia Antigen><B blood cells><B cell><B cells><B-Cells><B-Lymphocytes><B-cell><Bioassay><Biological><Biological Assay><Blood Serum><Bp50><Bypass><CD134L><CD4 Cells><CD4 Positive T Lymphocytes><CD4 T cells><CD4 helper T cell><CD4 lymphocyte><CD4+ T-Lymphocyte><CD4-Positive Lymphocytes><CD40><CD8 Cell><CD8 T cells><CD8 lymphocyte><CD8+ T cell><CD8+ T-Lymphocyte><CD8-Positive Lymphocytes><CD8-Positive T-Lymphocytes><CDW40><Cell Communication><Cell Communication and Signaling><Cell Interaction><Cell Signaling><Cell-to-Cell Interaction><Cessation of life><Child><Child Youth><Children (0-21)><Chronic Hepatitis B><Cirrhosis><Clinical><Clinical Research><Clinical Study><Clinical Treatment><Clinical Treatment Moab><Clinical Trials><Co-culture><Cocultivation><Coculture><Coculture Techniques><Cytometry><Data><Death><Defect><Dendritic Cells><Diagnosis><Drugs><Environment><Fatal Outcome><Flow Cytofluorometries><Flow Cytofluorometry><Flow Cytometry><Flow Microfluorimetry><Flow Microfluorometry><Frequencies><GP34><Gene Expression><Genes><Goals><HBV><HBV disease><HBV infected individuals><HBV infection><HBV infection in patients><HBV infection in people><HBV patients><HBsAg><HepB><Hepatic><Hepatic Cells><Hepatic Failure><Hepatic Parenchyma><Hepatic Parenchymal Cell><Hepatic Tissue><Hepatitis B><Hepatitis B Infection><Hepatitis B Surface Antigens><Hepatitis B Virus><Hepatocarcinoma><Hepatocellular Carcinoma><Hepatocellular cancer><Hepatocyte><Hepatoma><Human><Image><Immune><Immune response><Immune system><Immunes><Immunity><Immunochemical Immunologic><Immunohistochemistry><Immunohistochemistry Cell/Tissue><Immunohistochemistry Staining Method><Immunologic><Immunological><Immunologically><Immunologics><Immunomodulation><In Vitro><Infection><Injury to Liver><Intervention><Intracellular Communication and Signaling><Investigation><Laboratories><Licensing><Life><Liver><Liver Cells><Liver Cells Carcinoma><Liver Failure><Liver parenchyma><Long-term infection><MGC9013><Mediating><Medication><Mice><Mice Mammals><Modern Man><Monoclonal Antibodies><Murine><Mus><OX40L><Outcome><Pathway interactions><Patient Participation><Persons><Pharmaceutical Preparations><Phenocopy><Population><Primary Malignant Neoplasm of Liver><Primary carcinoma of the liver cells><Primary liver cancer><Publishing><Relapse><Research><Role><Serology><Serum><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><Sorting><Source><Spleen><Spleen Reticuloendothelial System><T cell response><T-Cell Activation><T-Cells><T-Lymphocyte><T4 Cells><T4 Lymphocytes><T8 Cells><T8 Lymphocytes><TNFRSF5><TNFRSF5 gene><TNFSF4><TNFSF4 gene><TXGP1><Testing><Therapeutic><Transgenic Mice><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><Veiled Cells><Viral><Viral Hepatitis B><Virus><Withdrawal><Work><accessory cell><activate T cells><adulthood><age associated><age associated difference><age based difference><age correlated><age dependent><age dependent difference><age dependent variation><age difference><age linked><age related><age related difference><age related variation><age specific><age specific difference><ages><analog><attenuate><attenuates><attributable death><attributable mortality><biologic><biological signal transduction><chronic HBV infection><chronic hepatitis B infection><chronic hepatitis B virus infection><chronic infection><chronic infections with hepatitis B virus><chronic liver injury><chronically infected with HBV><chronically infected with hepatitis B><cirrhotic><clinical intervention><clinical relevance><clinical therapy><clinically relevant><cohort><differ by age><difference across age><difference in age><differential expression><differentially expressed><draining lymph node><drug/agent><end stage liver disease><end stage liver failure><experiment><experimental research><experimental study><experiments><flow cytophotometry><hep B><hepatic body system><hepatic damage><hepatic injury><hepatic organ system><hepatitis B patients><hepatitis B viral infection><hepatitis B virus disease><hepatitis B virus infected individuals><hepatitis B virus infection><hepatitis B virus infection in patients><hepatitis B virus infection in people><host response><imaging><immune modulation><immune regulation><immune system response><immunogen><immunologic reactivity control><immunomodulatory><immunoregulation><immunoregulatory><immunoresponse><in vitro Assay><in vivo><individuals with HBV><individuals with hepatitis B><infected with HBV><infected with hepatitis B><infected with hepatitis B virus><infection with HBV><infection with hepatitis B virus><insight><kids><liver carcinoma><liver damage><liver injury><mAbs><monoclonal Abs><mouse model><murine model><neonate><next generation><p50><pathway><patients with HBV><patients with hepatitis B><people with HBV><people with hepatitis B><persistent infection><prevent><preventing><regional lymph node><response><scRNA sequencing><scRNA-seq><secondary lymph organ><secondary lymphatic organ><secondary lymphoid organ><single cell RNA-seq><single cell RNAseq><single cell expression profiling><single cell transcriptomic profiling><single-cell RNA sequencing><social role><therapeutic target><thymus derived lymphocyte><trafficking><transcriptional differences><transcriptomics><trial regimen><trial treatment><variation by age><viral infectious disease treatment><youngster>
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Blake Sells

WASHINGTON UNIVERSITY, SAINT LOUIS, MO

Exploratory lead · 40/100
Training-friendly
Recent
Active award
$36,622
FY 2026

Project Title

Dissecting how activated immunity reshapes the stromal TME of pancreatic ductal adenocarcinoma

Grant Number:

5F30CA298121-02

Activity Code:

F30

Mechanism:

Training, Individual

Agency:

NIH

Start Date:

4/1/2025

End Date:

3/31/2029

Why this may be worth a closer look

  • • Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

Project Summary / Abstract Immunotherapy has been shown to be effective in several cancer types leading to enhancement in long-term survival in subsets of patients. However, there are no proven effective immunotherapeutic approaches for pancreatic ductal adenocarcinoma (PDAC)1. There are many reaso...

Research Terms

<Agonist><Antibodies><Antigen Presentation><Antigen-Presenting Cells><Antigens><Basic Research><Basic Science><Bp50><CD105><CD105 Gene><CD40><CDW40><Cancer Model><CancerModel><Cancers><Cell Body><Cell Count><Cell Function><Cell Number><Cell Physiology><Cell Process><Cell-Extracellular Matrix><Cells><Cellular Function><Cellular Physiology><Cellular Process><Characteristics><Clinical><Clinical Trials><Collagen><Combination immunotherapy><Consensus><Data><Dendritic Cells><Deposit><Deposition><Desmoplastic><Desmoplastic Reaction><Development><Dysfunction><ECM><END Gene><ENG gene><Endoglin Gene><Endothelial Cells><Exclusion><Extracellular Matrix><FLK2><FLT 3 Ligand><FLT3><FLT3 gene><FLT3 ligand><FLT3L><FLT3LG><FLT3LG gene><FMS-Related Tyrosine Kinase 3 Ligand Gene><FMS-Related Tyrosine Kinase-3 Ligand><FMS-like tyrosine kinase 3><Failure><Fibroblasts><Fibrosis><Fms-Related Tyrosine Kinase 3><Functional disorder><Goals><HHT1><HHT1 Gene><Heterogeneity><Human><IFN><Immune><Immune infiltrates><Immune mediated therapy><Immunes><Immunity><Immunologically Directed Therapy><Immunology><Immunotherapeutic agent><Immunotherapy><Impairment><Inflammatory><Interferons><Investigators><Kinetics><MGC9013><Malignant Neoplasms><Malignant Tumor><Mediating><Mice><Mice Mammals><Modern Man><Murine><Mus><Myofibroblast><ORW Gene><ORW1><ORW1 Gene><PDA model><PDAC Model><Pancreas Ductal Adenocarcinoma><Pancreatic Ductal Adenocarcinoma><Patients><Ph D student><Ph D. student><Ph. D. student><Ph.D student><Ph.D. student><PhD student><PhD. student><Phenotype><Physicians><Physiopathology><Play><Population><Process><Productivity><Proteins><Proteomics><Publishing><Research Personnel><Researchers><Resistance><Role><STK-1 kinase><STK1><STK1-ligand><Sampling><Science><Scientist><Shapes><Stem Cell Tyrosine Kinase 1><Stromal Neoplasm><Stromal Tumor><Subcellular Process><T cell infiltration><T cell response><T-Cell Activation><T-Cells><T-Lymphocyte><TNFRSF5><TNFRSF5 gene><Therapeutic><Tumor Immunity><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><Tumor Promotion><Veiled Cells><Work><accessory cell><activate T cells><anti-tumor immunity><antitumor immunity><cancer immunity><cancer immunology><cancer microenvironment><cancer progression><cancer type><check point immunotherapy><check point inhibitor therapy><check point inhibitory therapy><check point therapy><checkpoint immunotherapy><checkpoint inhibitor therapy><checkpoint inhibitory therapy><checkpoint therapy><clinical implementation><combinatorial immunotherapy><developmental><doctoral student><dual immunotherapy><fetal liver kinase-2><fetal liver kinase-3><flk2 ligand><flk2-flt3 ligand><flt3 ligand protein><immune cell infiltrate><immune check point therapy><immune checkpoint therapy><immune drugs><immune microenvironment><immune therapeutic approach><immune therapeutic interventions><immune therapeutic regimens><immune therapeutic strategy><immune therapy><immune-based therapeutics><immune-based therapies><immune-based treatments><immuno therapy><immunogen><immunogenicity><immunologic therapeutics><immunosuppressive microenvironment><immunosuppressive tumor microenvironment><immunotherapeutics><immunotherapy agent><improved><insight><malignancy><mouse model><murine model><neoplasm immunology><neoplasm progression><neoplasm/cancer><neoplastic progression><p50><pancreatic ductal adenocarcinoma model><pathophysiology><patient subclass><patient subcluster><patient subgroups><patient subpopulations><patient subsets><patient subtypes><phenotypic biomarker><phenotypic marker><rational design><resistant><response><senescence><senescent><social role><spatial and temporal><spatial temporal><spatiotemporal><stem cell tyrosine kinase 1 ligand><thymus derived lymphocyte><training opportunity><translational study><tumor><tumor immune microenvironment><tumor immunology><tumor microenvironment><tumor progression><tumor-immune system interactions>
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JOHN C. FORTNEY

UNIVERSITY OF WASHINGTON, SEATTLE, WA

Exploratory lead · 38/100
Training-friendly
Solid budget
Active award
$346,324
FY 2025

Project Title

Integrated Mental Health Fellowship

Grant Number:

5T32MH020021-27

Activity Code:

T32

Mechanism:

Training, Institutional

Agency:

NIH

Start Date:

8/1/1998

End Date:

6/30/2029

Why this may be worth a closer look

  • • Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

The proposed T32, Integrated Mental Health Fellowship, is designed to train clinician scientists who are interested in improving the quality of mental health care delivered in primary care, medical subspecialty, and school-based clinics. Faculty supervisors will include senior investigators in the U...

Research Terms

<Fellowship><Mental Health><Mental Hygiene><Psychological Health>
View Full Project Details on NIH Reporter
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JURGEN UNUTZER

UNIVERSITY OF WASHINGTON, SEATTLE, WA

Exploratory lead · 38/100
Training-friendly
Solid budget
Active award
$346,324
FY 2025

Project Title

Integrated Mental Health Fellowship

Grant Number:

5T32MH020021-27

Activity Code:

T32

Mechanism:

Training, Institutional

Agency:

NIH

Start Date:

8/1/1998

End Date:

6/30/2029

Why this may be worth a closer look

  • • Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

The proposed T32, Integrated Mental Health Fellowship, is designed to train clinician scientists who are interested in improving the quality of mental health care delivered in primary care, medical subspecialty, and school-based clinics. Faculty supervisors will include senior investigators in the U...

Research Terms

<Fellowship><Mental Health><Mental Hygiene><Psychological Health>
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Cheryl L. Walker

BAYLOR COLLEGE OF MEDICINE, HOUSTON, TX

Exploratory lead · 38/100
Training-friendly
Solid budget
Active award
$320,816
FY 2025

Project Title

Training in Precision Environmental Health Sciences

Grant Number:

5T32ES027801-07

Activity Code:

T32

Mechanism:

Training, Institutional

Agency:

NIH

Start Date:

7/1/2018

End Date:

6/30/2029

Why this may be worth a closer look

  • • Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

Precision Environmental Health seeks to understand how environmental exposures influence human health and disease, and use this knowledge for new prevention and intervention strategies. The Training in Precision Environmental Health Sciences (TPEHS) Program is a joint initiative of Baylor College of...

Research Terms

<Environmental Health><Environmental Health Science><Training>
View Full Project Details on NIH Reporter
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Jill P Buyon

NEW YORK UNIVERSITY SCHOOL OF MEDICINE, NEW YORK, NY

Exploratory lead · 38/100
Training-friendly
Solid budget
Active award
$310,474
FY 2025

Project Title

Translational Basic and Clinical Research Training in Rheumatology

Grant Number:

5T32AR069515-09

Activity Code:

T32

Mechanism:

Training, Institutional

Agency:

NIH

Start Date:

5/1/2017

End Date:

5/31/2027

Why this may be worth a closer look

  • • Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

The Translational Basic and Clinical Research Training in Rheumatology, led in its first cycle by NYU Rheumatology Division Director Dr. Jill Buyon, will in its second cycle be co-directed under an mPI arrangement. Adding to Dr. Buyon’s extensive translational experience in SLE and autoimmunity, Dr....

Research Terms

<Basic Research><Basic Science><Clinical Research><Clinical Study><Research Training><Rheumatology>
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Jose U. Scher

NEW YORK UNIVERSITY SCHOOL OF MEDICINE, NEW YORK, NY

Exploratory lead · 38/100
Training-friendly
Solid budget
Active award
$310,474
FY 2025

Project Title

Translational Basic and Clinical Research Training in Rheumatology

Grant Number:

5T32AR069515-09

Activity Code:

T32

Mechanism:

Training, Institutional

Agency:

NIH

Start Date:

5/1/2017

End Date:

5/31/2027

Why this may be worth a closer look

  • • Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

The Translational Basic and Clinical Research Training in Rheumatology, led in its first cycle by NYU Rheumatology Division Director Dr. Jill Buyon, will in its second cycle be co-directed under an mPI arrangement. Adding to Dr. Buyon’s extensive translational experience in SLE and autoimmunity, Dr....

Research Terms

<Basic Research><Basic Science><Clinical Research><Clinical Study><Research Training><Rheumatology>
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Kelly P. Cosgrove

YALE UNIVERSITY, NEW HAVEN, CT

Exploratory lead · 38/100
Very recent
Active award
Career award
$210,453
FY 2026

Project Title

Mentoring in the Clinical Neuroscience of Alcohol Use Disorder

Grant Number:

5K24AA031345-03

Activity Code:

K24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

5/1/2024

End Date:

4/30/2029

Why this may be worth a closer look

  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

Project Summary This K24 Career Development Award in Patient-Oriented Research seeks support for a well-established, mid- career Professor in Psychiatry at Yale who has a track record of achievement in patient-oriented alcohol research, and a long-standing commitment to mentorship. Dr. Cosgrove lead...

Research Terms

<Achievement><Achievement Attainment><Alcohol Chemical Class><Alcoholic Liver Diseases><Alcoholic liver damage><Alcohols><Area><Award><Biological><Blood Plasma><Body System><Brain><Brain Nervous System><Brain imaging><COBRE><Career Development Awards><Career Development Awards and Programs><Career Development Programs K-Series><Cell Body><Cells><Center of Biomedical Research Excellence><Centers of Research Excellence><Clinical><Clinical Treatment><Cognition><Collection><Data><Data Collection><Data Set><Development><Development Plans><Differences between sexes><Differs between sexes><Doctor of Philosophy><Dysfunction><ETOH level><Encephalon><Equilibrium><Faculty><Fostering><Functional disorder><Funding><Goals><Grant><History><Hortega cell><Imaging Procedures><Imaging Technics><Imaging Techniques><Immune><Immunes><Individual><Investigators><K-Awards><K-Series Research Career Programs><K24 Award><Knowledge><Liver><Maintenance><Manuscripts><Measures><Mentors><Mentorship><Microglia><Mid-Career Clinical Scientist Award (K24)><Moods><NIAAA><National Institute on Alcohol Abuse and Alcoholism><Nerve Degeneration><Neurocognitive><Neuron Degeneration><Neurosciences><Organ System><P50 Mechanism><P50 Program><PET><PET Scan><PET imaging><PETSCAN><PETT><Participant><Persons><Ph.D.><PhD><Physiopathology><Plasma><Plasma Serum><Positron Emission Tomography Medical Imaging><Positron Emission Tomography Scan><Positron-Emission Tomography><Postdoc><Postdoctoral Fellow><Psychiatry><R-Series Research Projects><R01 Mechanism><R01 Program><Rad.-PET><Recording of previous events><Recovery><Research><Research Associate><Research Career Program><Research Design><Research Ethics><Research Grants><Research Personnel><Research Project Grants><Research Projects><Researchers><Reticuloendothelial System, Serum, Plasma><Sampling><Scientist><Sex Differences><Sexual differences><Specialized Center><Stress><Study Type><Synapses><Synaptic><System><Techniques><Training><Treatment outcome><Woman><Work><Writing><alcohol abuse therapy><alcohol abuse treatment><alcohol induced hepatic injury><alcohol induced liver disorder><alcohol induced liver injury><alcohol level><alcohol liver damage><alcohol measurement><alcohol related liver disease><alcohol related research><alcohol research><alcohol treatment><alcohol use disorder><alcohol-associated liver disease><alcohol-induced hepatic damage><alcohol-induced hepatic dysfunction><alcohol-induced liver damage><alcohol-induced liver disease><alcohol-induced liver dysfunction><alcohol-mediated liver dysfunction><alcohol-mediated liver injury><alcohol-related liver disease><alcoholic liver injury><balance><balance function><biologic><biomarker identification><brain visualization><career><career development><class development><clinical intervention><clinical therapy><course development><course material development><density><developmental><drinking><ethanol induced hepatic injury><ethanol induced liver disorder><ethanol induced liver injury><ethanol liver disease><ethanol measurement><ethanol research><ethanol use disorder><ethanol-induced hepatic damage><ethanol-induced hepatic dysfunction><ethanol-induced liver damage><ethanol-induced liver disease><ethanol-induced liver dysfunction><ethanol-mediated liver dysfunction><ethanol-mediated liver injury><ethyl alcohol measurements><gitter cell><graduate student><hepatic body system><hepatic organ system><histories><identification of biomarkers><identification of new biomarkers><imaging biomarker><imaging marker><imaging-based biological marker><imaging-based biomarker><imaging-based marker><improved><interest><kappa opiate><kappa opioid><kappa opioid receptors><marker identification><meeting><meetings><men><mesoglia><metabolism measurement><metabolome><metabolomics><metabonome><metabonomics><microglial cell><microgliocyte><negative affect><negative affectivity><neural degeneration><neurochemical><neurochemistry><neurodegeneration><neurodegenerative><neurological degeneration><neuronal degeneration><new drug target><new druggable target><new pharmacotherapy target><new therapeutic target><new therapy target><novel drug target><novel druggable target><novel pharmacotherapy target><novel therapeutic target><novel therapy target><pathophysiology><patient centered><patient oriented><patient oriented research><patient oriented study><perivascular glial cell><positron emission tomographic (PET) imaging><positron emission tomographic imaging><positron emitting tomography><post-doc><post-doctoral><post-doctoral trainee><professor><programs><recruit><research associates><sex><sex based differences><sex-dependent differences><sex-related differences><sex-specific differences><skills><stress reactivity><student mentoring><student-led learning><study design><synapse><trial regimen><trial treatment><undergrad><undergraduate><undergraduate student><κ opiate><κ opioid><κ opioid receptors><κ-OR><κOR>
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GUADALUPE X AYALA

SAN DIEGO STATE UNIVERSITY, SAN DIEGO, CA

Exploratory lead · 38/100
Very recent
Active award
Team-scale grant
$75,239
FY 2026

Project Title

SDSU HealthLINK Center for Transdisciplinary Health Research: Strengthening Neighborhood Economic Opportunity to Prevent Adolescent Substance Use

Grant Number:

3U54MD012397-08S1

Activity Code:

U54

Mechanism:

Research Centers

Agency:

NIH

Start Date:

9/11/2018

End Date:

3/31/2029

Why this may be worth a closer look

  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

OVERALL – Project Summary The SDSU HealthLINK Center for Transdisciplinary Health Disparities Research (SDSU HealthLINK Center; Center) was established in 2018 to augment investigator, partner, and institutional capacity for minority health and health disparities (MHHD) research at SDSU and SDSU Imp...

Research Terms

<Address><Area><Behavioral><Biology><Biomedical Research><California><Clinical><Collaborations><Communities><Consent><Consultations><County><Coupled><Data><Data Science><Decrease health disparities><Development><Discipline><Doctor's Degree><Doctorate Degree><EXTMR><Economics><Educational workshop><Environment><Ethics><Evidence based practice><Extramural><Extramural Activities><Faculty><Fostering><Foundations><Funding><Generalized Growth><Goals><Grant><Growth><Health><Health Disparities Research><Health Inequity><Health Promotion><Health Services><Health Services Evaluation><Health Services Research><Health disparities related research><Health disparity mitigation><Health disparity reduction><Hispanic><Human Subject Research><Immigrant><Individual><Industry><Inequalities in Health><Inequities in Health><Infrastructure><Institution><Intervention><Investigators><Investments><Knowledge><LGBTQ><Latino><Lesbian Gay Bi-sexual Transgender Queer><Lesbian Gay Bisexual Transgender Queer><Letters><Lower health disparities><Medical Care Research><Methods><Mexico><Minority-Serving Institution><Mitigate health disparities><NCMHD><NIH><NIMHD><National Center on Minority Health and Health Disparities><National Institute of Minority Health and Health Disparities><National Institute on Minority Health and Health Disparities><National Institutes of Health><Neighborhoods><P50 Mechanism><P50 Program><Participant><Pilot Projects><Policies><Population><Population Research><Population-based research><Population-level research><Position><Positioning Attribute><Postdoc><Postdoctoral Fellow><Process><Progress Reports><Psychology><Public Health><R-Series Research Projects><R01 Mechanism><R01 Program><Reduce health disparities><Refugees><Research><Research Activity><Research Associate><Research Grants><Research Infrastructure><Research Personnel><Research Project Grants><Research Projects><Research Resources><Research Support><Research Training><Researchers><Resources><Rural><Rural Community><STEM Education><STEM knowledge><STEM research><Salutogenesis><Science><Science, Technology, Engineering and Math Education><Science, Technology, Engineering and Mathematics Education><Scientist><Services><Specialized Center><Strategic Planning><System><Tissue Growth><Training><Training Programs><Transcend><Translating><Translational Research><Translational Science><Translations><United States National Institutes of Health><Universities><Workshop><Writing><Youth><Youth 10-21><adolescent substance use><career><career development><community engaged participatory research><community engaged research><community engagement><community partnered research><community partners><community-based partners><community-engaged study><community-partnered study><consultation><cost><developmental><doctoral degree><economic><engagement with communities><ethical><evidence base><health determinants><health disparities science><health equity promotion><health inequalities><health science research><implementation science><improved><innovate><innovation><innovative><institutional capacity><investigate population><low SES><low socio-economic position><low socio-economic status><low socioeconomic position><low socioeconomic status><member><minority health><minority health disparity><minority institution><ontogeny><pilot study><population investigation><population level investigation><population specific research><post-doc><post-doctoral><post-doctoral trainee><prevent><preventing><professor><programs><promote health equity><promoting health><recovery services><recovery support services><recruit><research associates><response><science, technology, engineering and math knowledge><science, technology, engineering and math research><science, technology, engineering and mathematics knowledge><science, technology, engineering and mathematics research><services research><skills><studies of populations><study of the population><study population><substance use among adolescents><substance use among youth><success><survey population><tool><translation><translation research><translational investigation><uptake><youth age><youth substance use>
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Kristen Jennifer Wells

SAN DIEGO STATE UNIVERSITY, SAN DIEGO, CA

Exploratory lead · 38/100
Very recent
Active award
Team-scale grant
$75,239
FY 2026

Project Title

SDSU HealthLINK Center for Transdisciplinary Health Research: Strengthening Neighborhood Economic Opportunity to Prevent Adolescent Substance Use

Grant Number:

3U54MD012397-08S1

Activity Code:

U54

Mechanism:

Research Centers

Agency:

NIH

Start Date:

9/11/2018

End Date:

3/31/2029

Why this may be worth a closer look

  • • Award timing is recent enough to matter for outreach and opportunity scanning.

Project Abstract

OVERALL – Project Summary The SDSU HealthLINK Center for Transdisciplinary Health Disparities Research (SDSU HealthLINK Center; Center) was established in 2018 to augment investigator, partner, and institutional capacity for minority health and health disparities (MHHD) research at SDSU and SDSU Imp...

Research Terms

<Address><Area><Behavioral><Biology><Biomedical Research><California><Clinical><Collaborations><Communities><Consent><Consultations><County><Coupled><Data><Data Science><Decrease health disparities><Development><Discipline><Doctor's Degree><Doctorate Degree><EXTMR><Economics><Educational workshop><Environment><Ethics><Evidence based practice><Extramural><Extramural Activities><Faculty><Fostering><Foundations><Funding><Generalized Growth><Goals><Grant><Growth><Health><Health Disparities Research><Health Inequity><Health Promotion><Health Services><Health Services Evaluation><Health Services Research><Health disparities related research><Health disparity mitigation><Health disparity reduction><Hispanic><Human Subject Research><Immigrant><Individual><Industry><Inequalities in Health><Inequities in Health><Infrastructure><Institution><Intervention><Investigators><Investments><Knowledge><LGBTQ><Latino><Lesbian Gay Bi-sexual Transgender Queer><Lesbian Gay Bisexual Transgender Queer><Letters><Lower health disparities><Medical Care Research><Methods><Mexico><Minority-Serving Institution><Mitigate health disparities><NCMHD><NIH><NIMHD><National Center on Minority Health and Health Disparities><National Institute of Minority Health and Health Disparities><National Institute on Minority Health and Health Disparities><National Institutes of Health><Neighborhoods><P50 Mechanism><P50 Program><Participant><Pilot Projects><Policies><Population><Population Research><Population-based research><Population-level research><Position><Positioning Attribute><Postdoc><Postdoctoral Fellow><Process><Progress Reports><Psychology><Public Health><R-Series Research Projects><R01 Mechanism><R01 Program><Reduce health disparities><Refugees><Research><Research Activity><Research Associate><Research Grants><Research Infrastructure><Research Personnel><Research Project Grants><Research Projects><Research Resources><Research Support><Research Training><Researchers><Resources><Rural><Rural Community><STEM Education><STEM knowledge><STEM research><Salutogenesis><Science><Science, Technology, Engineering and Math Education><Science, Technology, Engineering and Mathematics Education><Scientist><Services><Specialized Center><Strategic Planning><System><Tissue Growth><Training><Training Programs><Transcend><Translating><Translational Research><Translational Science><Translations><United States National Institutes of Health><Universities><Workshop><Writing><Youth><Youth 10-21><adolescent substance use><career><career development><community engaged participatory research><community engaged research><community engagement><community partnered research><community partners><community-based partners><community-engaged study><community-partnered study><consultation><cost><developmental><doctoral degree><economic><engagement with communities><ethical><evidence base><health determinants><health disparities science><health equity promotion><health inequalities><health science research><implementation science><improved><innovate><innovation><innovative><institutional capacity><investigate population><low SES><low socio-economic position><low socio-economic status><low socioeconomic position><low socioeconomic status><member><minority health><minority health disparity><minority institution><ontogeny><pilot study><population investigation><population level investigation><population specific research><post-doc><post-doctoral><post-doctoral trainee><prevent><preventing><professor><programs><promote health equity><promoting health><recovery services><recovery support services><recruit><research associates><response><science, technology, engineering and math knowledge><science, technology, engineering and math research><science, technology, engineering and mathematics knowledge><science, technology, engineering and mathematics research><services research><skills><studies of populations><study of the population><study population><substance use among adolescents><substance use among youth><success><survey population><tool><translation><translation research><translational investigation><uptake><youth age><youth substance use>
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Pierre C Dagher

INDIANA UNIVERSITY INDIANAPOLIS, INDIANAPOLIS, IN

Exploratory lead · 36/100
Above-average budget
Active award
Team-scale grant
$878,240
FY 2025

Project Title

Indiana Center for Advanced Renal Microscopy and Molecular Imaging

Grant Number:

5U54DK137328-03

Activity Code:

U54

Mechanism:

Research Centers

Agency:

NIH

Start Date:

9/1/2023

End Date:

6/30/2028

Why this may be worth a closer look

  • • Award size is strong enough to merit immediate review.

Project Abstract

Project Summary/Abstract (Center Overview) From its inception as an NIDDK-funded P50 Center in 2002, the mission of the Indiana O’Brien Center for Advanced Renal Microscopy has been to provide renal researchers with effective access to advanced forms of microscopy. Over the past 20 years of continu...

Research Terms

<3-D><3-Dimensional><3D><Applications Grants><Biological><Body Tissues><Collaborations><Common Rat Strains><Communities><Cytometry><Data><Development><Diabetes Mellitus><Dysfunction><Educational workshop><Environment><Equipment><Functional disorder><Funding><Generations><Goals><Grant Proposals><Hematology><HuBMAP><Human BioMolecular Atlas Program><Image><Image Analyses><Image Analysis><Imaging technology><Indiana><Individual><Infrastructure><Institution><Investigators><Kidney><Kidney Urinary System><Left><Light><Methods><Mice><Mice Mammals><Microscopy><Mission><Molecular><Murine><Mus><NIDDK><NIH><National Institute of Diabetes and Digestive and Kidney Diseases><National Institutes of Health><Nebraska><Nephrology><Photoradiation><Physiology><Physiopathology><Publications><Quantitative Microscopy><Rat><Rats Mammals><Rattus><Renal Tissue><Reporter><Research><Research Personnel><Research Resources><Researchers><Resolution><Resource Development><Resources><Scientific Publication><Services><Techniques><Technology><Tissues><Training><United States National Institutes of Health><Universities><Washington><Work><Workshop><biologic><biomedical resource><career><computer imaging><design><designing><developmental><diabetes><digital imaging><experience><image evaluation><image interpretation><imaging><innovative technologies><intra-vital microscopy><intravital microscopy><microscope imaging><microscopic imaging><microscopy imaging><molecular imaging><molecule imaging><multi-photon><new technology><novel><novel technologies><outreach><pathophysiology><precision medicine><precision-based medicine><programs><renal><resolutions><spatial RNA sequencing><spatial gene expression analysis><spatial gene expression profiling><spatial resolved transcriptome sequencing><spatial transcriptome analysis><spatial transcriptome profiling><spatial transcriptome sequencing><spatial transcriptomics><spatially resolved transcriptomics><spatio transcriptomics><synergism><three dimensional><tool>
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Wah Chiu

STANFORD UNIVERSITY, STANFORD, CA

Exploratory lead · 36/100
Above-average budget
Active award
Team-scale grant
$700,000
FY 2025

Project Title

Stanford-SLAC CryoET Specimen Preparation Service Center (SCSC)

Grant Number:

5U24GM139166-06

Activity Code:

U24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

9/16/2020

End Date:

8/31/2026

Why this may be worth a closer look

  • • Award size is strong enough to merit immediate review.

Project Abstract

In response to the NIH RFA-RM-19-009, we propose to establish the Stanford-SLAC CryoET Specimen Preparation Service Center (SCSC) to accomplish four specific aims: (1) establish a platform, which is available to the scientific community at large, to streamline the preparation of samples suitable for...

Research Terms

<Academia><Adopted><Advisory Committees><Area><Award><Biocompatible Materials><Biological><Biomaterials><Biomedical Research><Body Tissues><Cell Body><Cell Components><Cell Structure><Cells><Cellular Structures><Collaborations><Communication><Communities><Complex><Cryo-electron Microscopy><Cryo-electron tomography><Cryoelectron Microscopy><Curriculum><Data Collection><Dedications><Educational Curriculum><Educational workshop><Electron Cryomicroscopy><Equipment><Evaluation><Fluorescence Light Microscopy><Fluorescence Microscopy><Freezing><Funding><Goals><Grant><Hydration><Hydration status><In Situ><Industry><Infrastructure><Institution><Intracellular Structure><Investigation><Investigators><Ions><Laboratories><Lifting><Macromolecular Complexes><Macromolecular Structure><Methods><Microscope><Molecular Structure><NIH><NIH RFA><National Institutes of Health><Organelles><P50 Mechanism><P50 Program><Preparation><Process><Productivity><Professional Organizations><Protocol><Protocols documentation><Recurrence><Recurrent><Request for Applications><Research><Research Personnel><Research Resources><Research Specimen><Researchers><Resource Allocation><Resources><Sampling><Scanning Electron Microscopy><Schedule><Scientist><Selection Criteria><Services><Specialized Center><Specimen><Subcellular structure><Task Forces><Techniques><Technology><Tissue Sample><Tissues><Titan><Training><Training Activity><United States National Institutes of Health><Work><Workshop><advisory team><biologic><biological material><conference><convention><cryo-EM><cryo-EM tomography><cryoEM><cryoEM tomography><cryoelectron tomography><cryogenic electron microscopy><cryogenics><data management><electron cryo-tomography><electron tomography><experience><experiment><experimental research><experimental study><experiments><image-based method><imaging method><imaging modality><innovative technologies><instrument><instrumentation><interest><internet portal><lesson plans><member><nanometer resolution><on-line portal><online portal><operation><operations><preparations><professional association><professional membership><professional society><programs><response><structural biology><summit><symposia><symposium><tool><training module><web portal><web-based portal>
View Full Project Details on NIH Reporter
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Hans Gregersen

CALIFORNIA MEDICAL INNOVATIONS INSTITUTE, SAN DIEGO, CA

Exploratory lead · 36/100
Likely hiring
Solid budget
$370,000
FY 2025

Project Title

Fecobionics monitoring and prediction of biofeedback therapy outcome in patients with obstructed defecation.

Grant Number:

5R01DK134689-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2023

End Date:

2/28/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

ABSTRACT Defecatory disorders affect 25% of the population and they are poorly recognized and treated. The incidence of defecatory disorders including chronic constipation is rising and it poses a major healthcare burden. The underlying mechanisms for these disorders are often not well understood. O...

Research Terms

<Abdomen><Affect><After Care><After-Treatment><Aftercare><Aging><American><Anal Incontinence><Anal Sphincter><Area><Ataxia><Ataxy><Biofeedback Approach><Biofeedback Therapy><Biofeedback Training><Biofeedback Treatment><Biomechanics><Bionics><Bowel incontinence><Chronic><Classification><Clinical Management><Clinical Trials><Constipation><Coordination Impairment><Cost Savings><Data><Defecation><Defecography><Defect><Development><Devices><Diagnosis><Diagnostic><Diagnostic tests><Diet><Dimensions><Disease><Disorder><Dyssynergia><Electronics><Exercise><Expenditure><Fecal Incontinence><Feces><Friends><Goals><Graphical interface><Health Care Systems><High Prevalence><Home><Hydrogen Oxide><Incidence><Individual><Intestinal><Intestines><Lateral><Laxative Preparation><Length><Liquid substance><MR Imaging><MR Tomography><MRI><MRIs><Magnetic Resonance Imaging><Manometry><Manometry Biochemistry><Maps><Measurement><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Medicine><Monitor><Muscle><Muscle Tissue><NMR Imaging><NMR Tomography><Nuclear Magnetic Resonance Imaging><Outcome><P50 Mechanism><P50 Program><Patients><Pattern><Pelvic><Pelvic Floor><Pelvic Floor Muscle><Pelvic Region><Pelvic floor structure><Pelvis><Physiologic><Physiological><Physiology><Play><Population><Position><Positioning Attribute><Posture><Procedures><Process><Property><QOL improvement><Radiation><Randomization trial><Reaction><Records><Rectum><Research><Resolution><Rest><Risk><Role><Sensory><Shapes><Specialized Center><Symptoms><System><Systematics><Technology><Test Result><Testing><Time><Training><Treatment outcome><Visualization><Water><Zeugmatography><anorectal disorder><biomechanical><bowel><bowel movement><clinical practice><cost><data integration><developmental><diets><electronic><electronic device><fluid><graphic user interface><graphical user interface><health care burden><homes><improved><improvements in QOL><improvements in quality of life><indexing><innovate><innovation><innovative><insight><laxative><liquid><muscular><neuromuscular><new technology><novel><novel technologies><optimal therapies><optimal treatments><outcome prediction><point of care><post treatment><pressure><programs><quality of life improvement><randomized trial><resolutions><responders and non-responders><responders from non-responders><responders or non-responders><responders versus non-responders><responders vs non-responders><responders/nonresponders><response><social role><software user interface><sphincter ani muscle structure><stool><success><therapeutic outcome><therapy outcome><therapy responders><tool><treatment responders><visual feedback>
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GHASSAN S KASSAB

CALIFORNIA MEDICAL INNOVATIONS INSTITUTE, SAN DIEGO, CA

Exploratory lead · 36/100
Likely hiring
Solid budget
$370,000
FY 2025

Project Title

Fecobionics monitoring and prediction of biofeedback therapy outcome in patients with obstructed defecation.

Grant Number:

5R01DK134689-03

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/1/2023

End Date:

2/28/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

ABSTRACT Defecatory disorders affect 25% of the population and they are poorly recognized and treated. The incidence of defecatory disorders including chronic constipation is rising and it poses a major healthcare burden. The underlying mechanisms for these disorders are often not well understood. O...

Research Terms

<Abdomen><Affect><After Care><After-Treatment><Aftercare><Aging><American><Anal Incontinence><Anal Sphincter><Area><Ataxia><Ataxy><Biofeedback Approach><Biofeedback Therapy><Biofeedback Training><Biofeedback Treatment><Biomechanics><Bionics><Bowel incontinence><Chronic><Classification><Clinical Management><Clinical Trials><Constipation><Coordination Impairment><Cost Savings><Data><Defecation><Defecography><Defect><Development><Devices><Diagnosis><Diagnostic><Diagnostic tests><Diet><Dimensions><Disease><Disorder><Dyssynergia><Electronics><Exercise><Expenditure><Fecal Incontinence><Feces><Friends><Goals><Graphical interface><Health Care Systems><High Prevalence><Home><Hydrogen Oxide><Incidence><Individual><Intestinal><Intestines><Lateral><Laxative Preparation><Length><Liquid substance><MR Imaging><MR Tomography><MRI><MRIs><Magnetic Resonance Imaging><Manometry><Manometry Biochemistry><Maps><Measurement><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Medicine><Monitor><Muscle><Muscle Tissue><NMR Imaging><NMR Tomography><Nuclear Magnetic Resonance Imaging><Outcome><P50 Mechanism><P50 Program><Patients><Pattern><Pelvic><Pelvic Floor><Pelvic Floor Muscle><Pelvic Region><Pelvic floor structure><Pelvis><Physiologic><Physiological><Physiology><Play><Population><Position><Positioning Attribute><Posture><Procedures><Process><Property><QOL improvement><Radiation><Randomization trial><Reaction><Records><Rectum><Research><Resolution><Rest><Risk><Role><Sensory><Shapes><Specialized Center><Symptoms><System><Systematics><Technology><Test Result><Testing><Time><Training><Treatment outcome><Visualization><Water><Zeugmatography><anorectal disorder><biomechanical><bowel><bowel movement><clinical practice><cost><data integration><developmental><diets><electronic><electronic device><fluid><graphic user interface><graphical user interface><health care burden><homes><improved><improvements in QOL><improvements in quality of life><indexing><innovate><innovation><innovative><insight><laxative><liquid><muscular><neuromuscular><new technology><novel><novel technologies><optimal therapies><optimal treatments><outcome prediction><point of care><post treatment><pressure><programs><quality of life improvement><randomized trial><resolutions><responders and non-responders><responders from non-responders><responders or non-responders><responders versus non-responders><responders vs non-responders><responders/nonresponders><response><social role><software user interface><sphincter ani muscle structure><stool><success><therapeutic outcome><therapy outcome><therapy responders><tool><treatment responders><visual feedback>
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Suvarna Alladi

EMORY UNIVERSITY, ATLANTA, GA

Exploratory lead · 36/100
Likely hiring
Active award
$104,179
FY 2025

Project Title

P-CARRS-BRAIN: Multi-domain (genetic, socio-behavioral, vascular) risk factors and prediction of Alzheimer’s Disease continuum in South Asians in India

Grant Number:

3R01AG089759-02S3

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2024

End Date:

8/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY/ABSTRACT While it is widely acknowledged that Alzheimer’s disease and related dementias (AD/ADRD) have an extended preclinical phase, there are sparse data on the cognitive and pathobiological changes in middle-ages, a critical window for preventative intervention in people likely to...

Research Terms

<21+ years old><AD dementia><AD pathology><AD related dementia><ADRD><AI Augmented><AI assisted><AI driven><AI enhanced><AI integrated><AI powered><Active Follow-up><Address><Adult><Adult Human><Age><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's biomarker><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease biological marker><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease pathology><Alzheimer's disease related dementia><Alzheimer's pathology><Alzheimers Dementia><Alzheimer’s biological marker><Alzheimer’s disease biomarker><Amentia><Apoplexy><Arteriosclerotic Dementia><Artificial Intelligence enhanced><Asian group><Asian individual><Asian people><Asian population><Asians><Assessment instrument><Assessment tool><Astroprotein><Augmented by AI><Augmented by the AI><Augmented with AI><Augmented with the AI><Behavioral><Biological><Biological Markers><Blood Plasma><Blood Vessels><Brain><Brain Nervous System><Brain Vascular Accident><Causality><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Classification><Clinical><Cognition><Cognitive><Collection><Complex><Data><Data Management and Analysis Core><Data Management and Statistical Analysis Core><Data Management and Statistical Core><Dementia><Detection><Diabetes Mellitus><Diagnosis><Digital biomarker><Disease><Disorder><Dyslipidemias><Early Diagnosis><Encephalon><Enrollment><Epidemic><Epidemiology><Etiology><European><Exhibits><Female><Funding><GFA-Protein><GFAP><GWA study><GWAS><Genetic><Genetic Risk><Genomics><Genotype><Glial Fibrillary Acid Protein><Glial Fibrillary Acidic Protein><Glial Intermediate Filament Protein><Goals><Hypertension><Image><India><Individual><Infrastructure><Knowledge><Language><Lead><Life><Life Cycle><Life Cycle Stages><Life Style><Lifestyle><Linguistic><Linguistics><Link><Longitudinal Studies><MR Imaging><MR Tomography><MRI><MRIs><Machine Learning><Magnetic Resonance Imaging><Measurement><Measures><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Metabolic><Myocardium><NHLBI><NMR Imaging><NMR Tomography><National Heart, Lung, and Blood Institute><Natural History><Neuropsychologies><Neuropsychology><Nuclear Magnetic Resonance Imaging><Organ><Outcome><Participant><Pathway interactions><Pattern><Pb element><Persons><Phase><Phenotype><Plasma><Plasma Serum><Population><Predicting Risk><Predisposition><Preventative intervention><Prevention><Primary Senile Degenerative Dementia><Protocol><Protocols documentation><Research><Reticuloendothelial System, Serum, Plasma><Retina><Risk><Risk Factors><Sampling><Sleep><Social Behavior><South Asian><Span 20><Spectroscopy><Spectrum Analyses><Spectrum Analysis><Standardization><Statistical Methods><Stress><Stroke><Susceptibility><System><Systematics><Therapeutic><Vascular Cognitive Impairment><Vascular Dementia><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Zeugmatography><accelerated aging><accelerated biological age><accelerated biological aging><active followup><adulthood><age acceleration><aged><aged group><aged groups><aged individual><aged individuals><aged people><aged person><aged persons><aged population><aged populations><ages><aging population><artificial intelligence assisted><artificial intelligence augmented><artificial intelligence driven><artificial intelligence integrated><artificial intelligence powered><bio-markers><biobank><biologic><biologic marker><biomarker><biorepository><brain MR imaging><brain MRI><brain attack><brain magnetic resonance imaging><cardiac muscle><cardiometabolic><cardiometabolism><causation><cerebral MR imaging><cerebral MRI><cerebral magnetic resonance imaging><cerebral vascular accident><cerebrovascular accident><cerebrovascular contribution to cognitive impairment><cerebrovascular contributions to cognitive dysfunction><cerebrovascular contributions to dementia><cognitive change><cohort><computer based prediction><dementia risk><diabetes><digital><digital cognitive assessment><digital cognitive test><digital marker><disease causation><early detection><early onset><enhanced with AI><enhanced with Artificial Intelligence><enroll><entire genome><epidemiologic><epidemiological><experience><family structure><follow up><follow-up><followed up><followup><forecasting risk><full genome><gene locus><genetic locus><genome sequencing><genome wide association><genome wide association scan><genome wide association study><genomewide association scan><genomewide association study><genomic location><genomic locus><heart muscle><heavy metal Pb><heavy metal lead><high blood pressure><high dimensional data><high risk><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><imaging><intervention for prevention><late in life><late life><learning network><life course><literate><long-term study><longitudinal design><longitudinal experimental design><longitudinal outcome studies><longitudinal research design><longitudinal study design><machine based learning><machine learning based prediction model><machine learning based predictive model><machine learning prediction><machine learning prediction model><malleable risk><mid life><mid-life><middle age><middle aged><midlife><mild cognitive disorder><mild cognitive impairment><modifiable risk><multi-modal data><multi-modal datasets><multi-modality><multidimensional data><multidimensional datasets><multimodal data><multimodal datasets><multimodality><neural imaging><neuro-imaging><neuroimaging><neuroimaging biomarker><neuroimaging marker><neurological imaging><neuropsychologic><new marker><novel><novel biomarker><novel marker><pathway><phenotypic data><pollutant><population aging><population based><pre-clinical><preclinical><predict risk><predict risks><predicted risk><predicted risks><predicting risks><predictive modeling><predictive risk><predictive tools><predicts risk><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><primary degenerative dementia><retinal imaging><risk factor for dementia><risk for dementia><risk prediction><risk predictions><senile dementia of the Alzheimer type><social culture><social structural><social structure><socio-cultural><socio-demographics><socio-structural><sociobehavior><sociobehavioral><sociocultural><sociodemographics><sociostructural><statistic methods><stroked><strokes><vascular><vascular and cognitive impairment><vascular cognition impairment><vascular cognitive decline><vascular cognitive disease><vascular cognitive disorder><vascular cognitive dysfunction><vascular contributions in dementia><vascular contributions to cognitive decline><vascular contributions to cognitive impairment><vascular contributions to dementia><vascular disease and impaired cognition><vascular dysfunction resulting in cognitive decline><vascular related cognitive decline><vascular related cognitive impairment><vascular related dementia><whole genome><whole genome association analysis><whole genome association study><younger age><♀>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

ALLAN I LEVEY

EMORY UNIVERSITY, ATLANTA, GA

Exploratory lead · 36/100
Likely hiring
Active award
$104,179
FY 2025

Project Title

P-CARRS-BRAIN: Multi-domain (genetic, socio-behavioral, vascular) risk factors and prediction of Alzheimer’s Disease continuum in South Asians in India

Grant Number:

3R01AG089759-02S3

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2024

End Date:

8/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY/ABSTRACT While it is widely acknowledged that Alzheimer’s disease and related dementias (AD/ADRD) have an extended preclinical phase, there are sparse data on the cognitive and pathobiological changes in middle-ages, a critical window for preventative intervention in people likely to...

Research Terms

<21+ years old><AD dementia><AD pathology><AD related dementia><ADRD><AI Augmented><AI assisted><AI driven><AI enhanced><AI integrated><AI powered><Active Follow-up><Address><Adult><Adult Human><Age><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's biomarker><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease biological marker><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease pathology><Alzheimer's disease related dementia><Alzheimer's pathology><Alzheimers Dementia><Alzheimer’s biological marker><Alzheimer’s disease biomarker><Amentia><Apoplexy><Arteriosclerotic Dementia><Artificial Intelligence enhanced><Asian group><Asian individual><Asian people><Asian population><Asians><Assessment instrument><Assessment tool><Astroprotein><Augmented by AI><Augmented by the AI><Augmented with AI><Augmented with the AI><Behavioral><Biological><Biological Markers><Blood Plasma><Blood Vessels><Brain><Brain Nervous System><Brain Vascular Accident><Causality><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Classification><Clinical><Cognition><Cognitive><Collection><Complex><Data><Data Management and Analysis Core><Data Management and Statistical Analysis Core><Data Management and Statistical Core><Dementia><Detection><Diabetes Mellitus><Diagnosis><Digital biomarker><Disease><Disorder><Dyslipidemias><Early Diagnosis><Encephalon><Enrollment><Epidemic><Epidemiology><Etiology><European><Exhibits><Female><Funding><GFA-Protein><GFAP><GWA study><GWAS><Genetic><Genetic Risk><Genomics><Genotype><Glial Fibrillary Acid Protein><Glial Fibrillary Acidic Protein><Glial Intermediate Filament Protein><Goals><Hypertension><Image><India><Individual><Infrastructure><Knowledge><Language><Lead><Life><Life Cycle><Life Cycle Stages><Life Style><Lifestyle><Linguistic><Linguistics><Link><Longitudinal Studies><MR Imaging><MR Tomography><MRI><MRIs><Machine Learning><Magnetic Resonance Imaging><Measurement><Measures><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Metabolic><Myocardium><NHLBI><NMR Imaging><NMR Tomography><National Heart, Lung, and Blood Institute><Natural History><Neuropsychologies><Neuropsychology><Nuclear Magnetic Resonance Imaging><Organ><Outcome><Participant><Pathway interactions><Pattern><Pb element><Persons><Phase><Phenotype><Plasma><Plasma Serum><Population><Predicting Risk><Predisposition><Preventative intervention><Prevention><Primary Senile Degenerative Dementia><Protocol><Protocols documentation><Research><Reticuloendothelial System, Serum, Plasma><Retina><Risk><Risk Factors><Sampling><Sleep><Social Behavior><South Asian><Span 20><Spectroscopy><Spectrum Analyses><Spectrum Analysis><Standardization><Statistical Methods><Stress><Stroke><Susceptibility><System><Systematics><Therapeutic><Vascular Cognitive Impairment><Vascular Dementia><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Zeugmatography><accelerated aging><accelerated biological age><accelerated biological aging><active followup><adulthood><age acceleration><aged><aged group><aged groups><aged individual><aged individuals><aged people><aged person><aged persons><aged population><aged populations><ages><aging population><artificial intelligence assisted><artificial intelligence augmented><artificial intelligence driven><artificial intelligence integrated><artificial intelligence powered><bio-markers><biobank><biologic><biologic marker><biomarker><biorepository><brain MR imaging><brain MRI><brain attack><brain magnetic resonance imaging><cardiac muscle><cardiometabolic><cardiometabolism><causation><cerebral MR imaging><cerebral MRI><cerebral magnetic resonance imaging><cerebral vascular accident><cerebrovascular accident><cerebrovascular contribution to cognitive impairment><cerebrovascular contributions to cognitive dysfunction><cerebrovascular contributions to dementia><cognitive change><cohort><computer based prediction><dementia risk><diabetes><digital><digital cognitive assessment><digital cognitive test><digital marker><disease causation><early detection><early onset><enhanced with AI><enhanced with Artificial Intelligence><enroll><entire genome><epidemiologic><epidemiological><experience><family structure><follow up><follow-up><followed up><followup><forecasting risk><full genome><gene locus><genetic locus><genome sequencing><genome wide association><genome wide association scan><genome wide association study><genomewide association scan><genomewide association study><genomic location><genomic locus><heart muscle><heavy metal Pb><heavy metal lead><high blood pressure><high dimensional data><high risk><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><imaging><intervention for prevention><late in life><late life><learning network><life course><literate><long-term study><longitudinal design><longitudinal experimental design><longitudinal outcome studies><longitudinal research design><longitudinal study design><machine based learning><machine learning based prediction model><machine learning based predictive model><machine learning prediction><machine learning prediction model><malleable risk><mid life><mid-life><middle age><middle aged><midlife><mild cognitive disorder><mild cognitive impairment><modifiable risk><multi-modal data><multi-modal datasets><multi-modality><multidimensional data><multidimensional datasets><multimodal data><multimodal datasets><multimodality><neural imaging><neuro-imaging><neuroimaging><neuroimaging biomarker><neuroimaging marker><neurological imaging><neuropsychologic><new marker><novel><novel biomarker><novel marker><pathway><phenotypic data><pollutant><population aging><population based><pre-clinical><preclinical><predict risk><predict risks><predicted risk><predicted risks><predicting risks><predictive modeling><predictive risk><predictive tools><predicts risk><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><primary degenerative dementia><retinal imaging><risk factor for dementia><risk for dementia><risk prediction><risk predictions><senile dementia of the Alzheimer type><social culture><social structural><social structure><socio-cultural><socio-demographics><socio-structural><sociobehavior><sociobehavioral><sociocultural><sociodemographics><sociostructural><statistic methods><stroked><strokes><vascular><vascular and cognitive impairment><vascular cognition impairment><vascular cognitive decline><vascular cognitive disease><vascular cognitive disorder><vascular cognitive dysfunction><vascular contributions in dementia><vascular contributions to cognitive decline><vascular contributions to cognitive impairment><vascular contributions to dementia><vascular disease and impaired cognition><vascular dysfunction resulting in cognitive decline><vascular related cognitive decline><vascular related cognitive impairment><vascular related dementia><whole genome><whole genome association analysis><whole genome association study><younger age><♀>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Viswanathan Mohan

EMORY UNIVERSITY, ATLANTA, GA

Exploratory lead · 36/100
Likely hiring
Active award
$104,179
FY 2025

Project Title

P-CARRS-BRAIN: Multi-domain (genetic, socio-behavioral, vascular) risk factors and prediction of Alzheimer’s Disease continuum in South Asians in India

Grant Number:

3R01AG089759-02S3

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2024

End Date:

8/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY/ABSTRACT While it is widely acknowledged that Alzheimer’s disease and related dementias (AD/ADRD) have an extended preclinical phase, there are sparse data on the cognitive and pathobiological changes in middle-ages, a critical window for preventative intervention in people likely to...

Research Terms

<21+ years old><AD dementia><AD pathology><AD related dementia><ADRD><AI Augmented><AI assisted><AI driven><AI enhanced><AI integrated><AI powered><Active Follow-up><Address><Adult><Adult Human><Age><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's biomarker><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease biological marker><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease pathology><Alzheimer's disease related dementia><Alzheimer's pathology><Alzheimers Dementia><Alzheimer’s biological marker><Alzheimer’s disease biomarker><Amentia><Apoplexy><Arteriosclerotic Dementia><Artificial Intelligence enhanced><Asian group><Asian individual><Asian people><Asian population><Asians><Assessment instrument><Assessment tool><Astroprotein><Augmented by AI><Augmented by the AI><Augmented with AI><Augmented with the AI><Behavioral><Biological><Biological Markers><Blood Plasma><Blood Vessels><Brain><Brain Nervous System><Brain Vascular Accident><Causality><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Classification><Clinical><Cognition><Cognitive><Collection><Complex><Data><Data Management and Analysis Core><Data Management and Statistical Analysis Core><Data Management and Statistical Core><Dementia><Detection><Diabetes Mellitus><Diagnosis><Digital biomarker><Disease><Disorder><Dyslipidemias><Early Diagnosis><Encephalon><Enrollment><Epidemic><Epidemiology><Etiology><European><Exhibits><Female><Funding><GFA-Protein><GFAP><GWA study><GWAS><Genetic><Genetic Risk><Genomics><Genotype><Glial Fibrillary Acid Protein><Glial Fibrillary Acidic Protein><Glial Intermediate Filament Protein><Goals><Hypertension><Image><India><Individual><Infrastructure><Knowledge><Language><Lead><Life><Life Cycle><Life Cycle Stages><Life Style><Lifestyle><Linguistic><Linguistics><Link><Longitudinal Studies><MR Imaging><MR Tomography><MRI><MRIs><Machine Learning><Magnetic Resonance Imaging><Measurement><Measures><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Metabolic><Myocardium><NHLBI><NMR Imaging><NMR Tomography><National Heart, Lung, and Blood Institute><Natural History><Neuropsychologies><Neuropsychology><Nuclear Magnetic Resonance Imaging><Organ><Outcome><Participant><Pathway interactions><Pattern><Pb element><Persons><Phase><Phenotype><Plasma><Plasma Serum><Population><Predicting Risk><Predisposition><Preventative intervention><Prevention><Primary Senile Degenerative Dementia><Protocol><Protocols documentation><Research><Reticuloendothelial System, Serum, Plasma><Retina><Risk><Risk Factors><Sampling><Sleep><Social Behavior><South Asian><Span 20><Spectroscopy><Spectrum Analyses><Spectrum Analysis><Standardization><Statistical Methods><Stress><Stroke><Susceptibility><System><Systematics><Therapeutic><Vascular Cognitive Impairment><Vascular Dementia><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Zeugmatography><accelerated aging><accelerated biological age><accelerated biological aging><active followup><adulthood><age acceleration><aged><aged group><aged groups><aged individual><aged individuals><aged people><aged person><aged persons><aged population><aged populations><ages><aging population><artificial intelligence assisted><artificial intelligence augmented><artificial intelligence driven><artificial intelligence integrated><artificial intelligence powered><bio-markers><biobank><biologic><biologic marker><biomarker><biorepository><brain MR imaging><brain MRI><brain attack><brain magnetic resonance imaging><cardiac muscle><cardiometabolic><cardiometabolism><causation><cerebral MR imaging><cerebral MRI><cerebral magnetic resonance imaging><cerebral vascular accident><cerebrovascular accident><cerebrovascular contribution to cognitive impairment><cerebrovascular contributions to cognitive dysfunction><cerebrovascular contributions to dementia><cognitive change><cohort><computer based prediction><dementia risk><diabetes><digital><digital cognitive assessment><digital cognitive test><digital marker><disease causation><early detection><early onset><enhanced with AI><enhanced with Artificial Intelligence><enroll><entire genome><epidemiologic><epidemiological><experience><family structure><follow up><follow-up><followed up><followup><forecasting risk><full genome><gene locus><genetic locus><genome sequencing><genome wide association><genome wide association scan><genome wide association study><genomewide association scan><genomewide association study><genomic location><genomic locus><heart muscle><heavy metal Pb><heavy metal lead><high blood pressure><high dimensional data><high risk><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><imaging><intervention for prevention><late in life><late life><learning network><life course><literate><long-term study><longitudinal design><longitudinal experimental design><longitudinal outcome studies><longitudinal research design><longitudinal study design><machine based learning><machine learning based prediction model><machine learning based predictive model><machine learning prediction><machine learning prediction model><malleable risk><mid life><mid-life><middle age><middle aged><midlife><mild cognitive disorder><mild cognitive impairment><modifiable risk><multi-modal data><multi-modal datasets><multi-modality><multidimensional data><multidimensional datasets><multimodal data><multimodal datasets><multimodality><neural imaging><neuro-imaging><neuroimaging><neuroimaging biomarker><neuroimaging marker><neurological imaging><neuropsychologic><new marker><novel><novel biomarker><novel marker><pathway><phenotypic data><pollutant><population aging><population based><pre-clinical><preclinical><predict risk><predict risks><predicted risk><predicted risks><predicting risks><predictive modeling><predictive risk><predictive tools><predicts risk><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><primary degenerative dementia><retinal imaging><risk factor for dementia><risk for dementia><risk prediction><risk predictions><senile dementia of the Alzheimer type><social culture><social structural><social structure><socio-cultural><socio-demographics><socio-structural><sociobehavior><sociobehavioral><sociocultural><sociodemographics><sociostructural><statistic methods><stroked><strokes><vascular><vascular and cognitive impairment><vascular cognition impairment><vascular cognitive decline><vascular cognitive disease><vascular cognitive disorder><vascular cognitive dysfunction><vascular contributions in dementia><vascular contributions to cognitive decline><vascular contributions to cognitive impairment><vascular contributions to dementia><vascular disease and impaired cognition><vascular dysfunction resulting in cognitive decline><vascular related cognitive decline><vascular related cognitive impairment><vascular related dementia><whole genome><whole genome association analysis><whole genome association study><younger age><♀>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Kabayam M Venkat Narayan

EMORY UNIVERSITY, ATLANTA, GA

Exploratory lead · 36/100
Likely hiring
Active award
$104,179
FY 2025

Project Title

P-CARRS-BRAIN: Multi-domain (genetic, socio-behavioral, vascular) risk factors and prediction of Alzheimer’s Disease continuum in South Asians in India

Grant Number:

3R01AG089759-02S3

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2024

End Date:

8/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY/ABSTRACT While it is widely acknowledged that Alzheimer’s disease and related dementias (AD/ADRD) have an extended preclinical phase, there are sparse data on the cognitive and pathobiological changes in middle-ages, a critical window for preventative intervention in people likely to...

Research Terms

<21+ years old><AD dementia><AD pathology><AD related dementia><ADRD><AI Augmented><AI assisted><AI driven><AI enhanced><AI integrated><AI powered><Active Follow-up><Address><Adult><Adult Human><Age><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's biomarker><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease biological marker><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease pathology><Alzheimer's disease related dementia><Alzheimer's pathology><Alzheimers Dementia><Alzheimer’s biological marker><Alzheimer’s disease biomarker><Amentia><Apoplexy><Arteriosclerotic Dementia><Artificial Intelligence enhanced><Asian group><Asian individual><Asian people><Asian population><Asians><Assessment instrument><Assessment tool><Astroprotein><Augmented by AI><Augmented by the AI><Augmented with AI><Augmented with the AI><Behavioral><Biological><Biological Markers><Blood Plasma><Blood Vessels><Brain><Brain Nervous System><Brain Vascular Accident><Causality><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Classification><Clinical><Cognition><Cognitive><Collection><Complex><Data><Data Management and Analysis Core><Data Management and Statistical Analysis Core><Data Management and Statistical Core><Dementia><Detection><Diabetes Mellitus><Diagnosis><Digital biomarker><Disease><Disorder><Dyslipidemias><Early Diagnosis><Encephalon><Enrollment><Epidemic><Epidemiology><Etiology><European><Exhibits><Female><Funding><GFA-Protein><GFAP><GWA study><GWAS><Genetic><Genetic Risk><Genomics><Genotype><Glial Fibrillary Acid Protein><Glial Fibrillary Acidic Protein><Glial Intermediate Filament Protein><Goals><Hypertension><Image><India><Individual><Infrastructure><Knowledge><Language><Lead><Life><Life Cycle><Life Cycle Stages><Life Style><Lifestyle><Linguistic><Linguistics><Link><Longitudinal Studies><MR Imaging><MR Tomography><MRI><MRIs><Machine Learning><Magnetic Resonance Imaging><Measurement><Measures><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Metabolic><Myocardium><NHLBI><NMR Imaging><NMR Tomography><National Heart, Lung, and Blood Institute><Natural History><Neuropsychologies><Neuropsychology><Nuclear Magnetic Resonance Imaging><Organ><Outcome><Participant><Pathway interactions><Pattern><Pb element><Persons><Phase><Phenotype><Plasma><Plasma Serum><Population><Predicting Risk><Predisposition><Preventative intervention><Prevention><Primary Senile Degenerative Dementia><Protocol><Protocols documentation><Research><Reticuloendothelial System, Serum, Plasma><Retina><Risk><Risk Factors><Sampling><Sleep><Social Behavior><South Asian><Span 20><Spectroscopy><Spectrum Analyses><Spectrum Analysis><Standardization><Statistical Methods><Stress><Stroke><Susceptibility><System><Systematics><Therapeutic><Vascular Cognitive Impairment><Vascular Dementia><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Zeugmatography><accelerated aging><accelerated biological age><accelerated biological aging><active followup><adulthood><age acceleration><aged><aged group><aged groups><aged individual><aged individuals><aged people><aged person><aged persons><aged population><aged populations><ages><aging population><artificial intelligence assisted><artificial intelligence augmented><artificial intelligence driven><artificial intelligence integrated><artificial intelligence powered><bio-markers><biobank><biologic><biologic marker><biomarker><biorepository><brain MR imaging><brain MRI><brain attack><brain magnetic resonance imaging><cardiac muscle><cardiometabolic><cardiometabolism><causation><cerebral MR imaging><cerebral MRI><cerebral magnetic resonance imaging><cerebral vascular accident><cerebrovascular accident><cerebrovascular contribution to cognitive impairment><cerebrovascular contributions to cognitive dysfunction><cerebrovascular contributions to dementia><cognitive change><cohort><computer based prediction><dementia risk><diabetes><digital><digital cognitive assessment><digital cognitive test><digital marker><disease causation><early detection><early onset><enhanced with AI><enhanced with Artificial Intelligence><enroll><entire genome><epidemiologic><epidemiological><experience><family structure><follow up><follow-up><followed up><followup><forecasting risk><full genome><gene locus><genetic locus><genome sequencing><genome wide association><genome wide association scan><genome wide association study><genomewide association scan><genomewide association study><genomic location><genomic locus><heart muscle><heavy metal Pb><heavy metal lead><high blood pressure><high dimensional data><high risk><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><imaging><intervention for prevention><late in life><late life><learning network><life course><literate><long-term study><longitudinal design><longitudinal experimental design><longitudinal outcome studies><longitudinal research design><longitudinal study design><machine based learning><machine learning based prediction model><machine learning based predictive model><machine learning prediction><machine learning prediction model><malleable risk><mid life><mid-life><middle age><middle aged><midlife><mild cognitive disorder><mild cognitive impairment><modifiable risk><multi-modal data><multi-modal datasets><multi-modality><multidimensional data><multidimensional datasets><multimodal data><multimodal datasets><multimodality><neural imaging><neuro-imaging><neuroimaging><neuroimaging biomarker><neuroimaging marker><neurological imaging><neuropsychologic><new marker><novel><novel biomarker><novel marker><pathway><phenotypic data><pollutant><population aging><population based><pre-clinical><preclinical><predict risk><predict risks><predicted risk><predicted risks><predicting risks><predictive modeling><predictive risk><predictive tools><predicts risk><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><primary degenerative dementia><retinal imaging><risk factor for dementia><risk for dementia><risk prediction><risk predictions><senile dementia of the Alzheimer type><social culture><social structural><social structure><socio-cultural><socio-demographics><socio-structural><sociobehavior><sociobehavioral><sociocultural><sociodemographics><sociostructural><statistic methods><stroked><strokes><vascular><vascular and cognitive impairment><vascular cognition impairment><vascular cognitive decline><vascular cognitive disease><vascular cognitive disorder><vascular cognitive dysfunction><vascular contributions in dementia><vascular contributions to cognitive decline><vascular contributions to cognitive impairment><vascular contributions to dementia><vascular disease and impaired cognition><vascular dysfunction resulting in cognitive decline><vascular related cognitive decline><vascular related cognitive impairment><vascular related dementia><whole genome><whole genome association analysis><whole genome association study><younger age><♀>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Dorairaj Prabhakaran

EMORY UNIVERSITY, ATLANTA, GA

Exploratory lead · 36/100
Likely hiring
Active award
$104,179
FY 2025

Project Title

P-CARRS-BRAIN: Multi-domain (genetic, socio-behavioral, vascular) risk factors and prediction of Alzheimer’s Disease continuum in South Asians in India

Grant Number:

3R01AG089759-02S3

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2024

End Date:

8/31/2029

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY/ABSTRACT While it is widely acknowledged that Alzheimer’s disease and related dementias (AD/ADRD) have an extended preclinical phase, there are sparse data on the cognitive and pathobiological changes in middle-ages, a critical window for preventative intervention in people likely to...

Research Terms

<21+ years old><AD dementia><AD pathology><AD related dementia><ADRD><AI Augmented><AI assisted><AI driven><AI enhanced><AI integrated><AI powered><Active Follow-up><Address><Adult><Adult Human><Age><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's biomarker><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease biological marker><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease pathology><Alzheimer's disease related dementia><Alzheimer's pathology><Alzheimers Dementia><Alzheimer’s biological marker><Alzheimer’s disease biomarker><Amentia><Apoplexy><Arteriosclerotic Dementia><Artificial Intelligence enhanced><Asian group><Asian individual><Asian people><Asian population><Asians><Assessment instrument><Assessment tool><Astroprotein><Augmented by AI><Augmented by the AI><Augmented with AI><Augmented with the AI><Behavioral><Biological><Biological Markers><Blood Plasma><Blood Vessels><Brain><Brain Nervous System><Brain Vascular Accident><Causality><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Classification><Clinical><Cognition><Cognitive><Collection><Complex><Data><Data Management and Analysis Core><Data Management and Statistical Analysis Core><Data Management and Statistical Core><Dementia><Detection><Diabetes Mellitus><Diagnosis><Digital biomarker><Disease><Disorder><Dyslipidemias><Early Diagnosis><Encephalon><Enrollment><Epidemic><Epidemiology><Etiology><European><Exhibits><Female><Funding><GFA-Protein><GFAP><GWA study><GWAS><Genetic><Genetic Risk><Genomics><Genotype><Glial Fibrillary Acid Protein><Glial Fibrillary Acidic Protein><Glial Intermediate Filament Protein><Goals><Hypertension><Image><India><Individual><Infrastructure><Knowledge><Language><Lead><Life><Life Cycle><Life Cycle Stages><Life Style><Lifestyle><Linguistic><Linguistics><Link><Longitudinal Studies><MR Imaging><MR Tomography><MRI><MRIs><Machine Learning><Magnetic Resonance Imaging><Measurement><Measures><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Metabolic><Myocardium><NHLBI><NMR Imaging><NMR Tomography><National Heart, Lung, and Blood Institute><Natural History><Neuropsychologies><Neuropsychology><Nuclear Magnetic Resonance Imaging><Organ><Outcome><Participant><Pathway interactions><Pattern><Pb element><Persons><Phase><Phenotype><Plasma><Plasma Serum><Population><Predicting Risk><Predisposition><Preventative intervention><Prevention><Primary Senile Degenerative Dementia><Protocol><Protocols documentation><Research><Reticuloendothelial System, Serum, Plasma><Retina><Risk><Risk Factors><Sampling><Sleep><Social Behavior><South Asian><Span 20><Spectroscopy><Spectrum Analyses><Spectrum Analysis><Standardization><Statistical Methods><Stress><Stroke><Susceptibility><System><Systematics><Therapeutic><Vascular Cognitive Impairment><Vascular Dementia><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Zeugmatography><accelerated aging><accelerated biological age><accelerated biological aging><active followup><adulthood><age acceleration><aged><aged group><aged groups><aged individual><aged individuals><aged people><aged person><aged persons><aged population><aged populations><ages><aging population><artificial intelligence assisted><artificial intelligence augmented><artificial intelligence driven><artificial intelligence integrated><artificial intelligence powered><bio-markers><biobank><biologic><biologic marker><biomarker><biorepository><brain MR imaging><brain MRI><brain attack><brain magnetic resonance imaging><cardiac muscle><cardiometabolic><cardiometabolism><causation><cerebral MR imaging><cerebral MRI><cerebral magnetic resonance imaging><cerebral vascular accident><cerebrovascular accident><cerebrovascular contribution to cognitive impairment><cerebrovascular contributions to cognitive dysfunction><cerebrovascular contributions to dementia><cognitive change><cohort><computer based prediction><dementia risk><diabetes><digital><digital cognitive assessment><digital cognitive test><digital marker><disease causation><early detection><early onset><enhanced with AI><enhanced with Artificial Intelligence><enroll><entire genome><epidemiologic><epidemiological><experience><family structure><follow up><follow-up><followed up><followup><forecasting risk><full genome><gene locus><genetic locus><genome sequencing><genome wide association><genome wide association scan><genome wide association study><genomewide association scan><genomewide association study><genomic location><genomic locus><heart muscle><heavy metal Pb><heavy metal lead><high blood pressure><high dimensional data><high risk><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><imaging><intervention for prevention><late in life><late life><learning network><life course><literate><long-term study><longitudinal design><longitudinal experimental design><longitudinal outcome studies><longitudinal research design><longitudinal study design><machine based learning><machine learning based prediction model><machine learning based predictive model><machine learning prediction><machine learning prediction model><malleable risk><mid life><mid-life><middle age><middle aged><midlife><mild cognitive disorder><mild cognitive impairment><modifiable risk><multi-modal data><multi-modal datasets><multi-modality><multidimensional data><multidimensional datasets><multimodal data><multimodal datasets><multimodality><neural imaging><neuro-imaging><neuroimaging><neuroimaging biomarker><neuroimaging marker><neurological imaging><neuropsychologic><new marker><novel><novel biomarker><novel marker><pathway><phenotypic data><pollutant><population aging><population based><pre-clinical><preclinical><predict risk><predict risks><predicted risk><predicted risks><predicting risks><predictive modeling><predictive risk><predictive tools><predicts risk><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><primary degenerative dementia><retinal imaging><risk factor for dementia><risk for dementia><risk prediction><risk predictions><senile dementia of the Alzheimer type><social culture><social structural><social structure><socio-cultural><socio-demographics><socio-structural><sociobehavior><sociobehavioral><sociocultural><sociodemographics><sociostructural><statistic methods><stroked><strokes><vascular><vascular and cognitive impairment><vascular cognition impairment><vascular cognitive decline><vascular cognitive disease><vascular cognitive disorder><vascular cognitive dysfunction><vascular contributions in dementia><vascular contributions to cognitive decline><vascular contributions to cognitive impairment><vascular contributions to dementia><vascular disease and impaired cognition><vascular dysfunction resulting in cognitive decline><vascular related cognitive decline><vascular related cognitive impairment><vascular related dementia><whole genome><whole genome association analysis><whole genome association study><younger age><♀>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Clifton W. Callaway

UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PITTSBURGH, PA

Exploratory lead · 34/100
Large award
Active award
$2,394,542
FY 2025

Project Title

The effect of SPecialty cAre on Recovery from Cardiac arrest (the SPARC trial)

Grant Number:

1R61HL175113-01A1

Activity Code:

R61

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/1/2025

End Date:

8/31/2026

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Abstract Cardiac arrest is common and deadly. Over 150,000 Americans are admitted to the hospital after resuscitation from cardiac arrest each year. These vulnerable patients require complex and time sensitive care to treat the causes and consequences of cardiac arrest. Delivery of excellent post-ar...

Research Terms

<21+ years old><Academy><Accident and Emergency department><Acute myocardial infarct><Acute myocardial infarction><Admission><Admission activity><Adult><Adult Human><Allografting><American><American Heart Association><Apoplexy><Asystole><Attention><Authorship><Brain Vascular Accident><Cardiac Arrest><Cardiopulmonary Resuscitation><Care Givers><Caregivers><Caring><Case Report Form><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Cessation of life><Clinical><Clinical Trials><Clinical Trials Data Monitoring Committees><Complex><Costs and Benefits><Critical Care><Critical Illness><Critically Ill><Data><Data Monitoring Committees><Data and Safety Monitoring Boards><Death><Development><Disclosure><Disease><Disorder><Emergency Department><Emergency room><Enrollment><Ensure><Environment><Family><Future><Health Care Facility><Health Facilities><Health Policy><Health system><Heart Arrest><Heterogeneity><Hospital Admission><Hospitalization><Hospitals><IRB><IRBs><Information Disclosure><Informed Consent><Institutional Review Boards><International><Intervention><Knowledge><Manuals><Medical><Medicine><Organ Donations><Outcome><P50 Mechanism><P50 Program><Patient Care><Patient Care Delivery><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Pennsylvania><Predicting Risk><Probability><Process><Provider><Public Health><Public Policy><Randomization trial><Randomized><Randomized, Controlled Trials><Recommendation><Recovery><Recovery of Function><Research Design><Research Resources><Resources><Risk Adjustment><Safety Monitoring Boards><Services><Societies><Source><Specialized Center><Specialty><Stroke><Study Type><Syndrome><System><Systems Development><Testing><Time><Tissue Donations><Trauma><Variant><Variation><adulthood><brain attack><cardiac resuscitation><care as usual><care facilities><care for patients><care of patients><care outcomes><care services><care systems><caring for patients><cerebral vascular accident><cerebrovascular accident><clinical practice><community consultation><cost><data dictionary><design><designing><development policy><developmental><enroll><experience><forecasting risk><functional outcomes><functional recovery><future implementation><health care outcomes><health care policy><heart resuscitation><hospital care><improved><medical specialties><operation><operations><out-of-hospital cardiac arrest><out-of-hospital sudden cardiac arrest><patient oriented outcomes><patient population><phase 2 trial><phase II trial><predict risk><predict risks><predicted risk><predicted risks><predicting risks><predictive risk><predicts risk><preference><primary outcome><randomisation><randomization><randomized control trial><randomized trial><randomly assigned><risk prediction><risk predictions><secondary analysis><stroked><strokes><study design><tertiary care><treatment as usual><trial comparing><trial enrollment><usual care>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jonathan Elmer

UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PITTSBURGH, PA

Exploratory lead · 34/100
Large award
Active award
$2,394,542
FY 2025

Project Title

The effect of SPecialty cAre on Recovery from Cardiac arrest (the SPARC trial)

Grant Number:

1R61HL175113-01A1

Activity Code:

R61

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/1/2025

End Date:

8/31/2026

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Abstract Cardiac arrest is common and deadly. Over 150,000 Americans are admitted to the hospital after resuscitation from cardiac arrest each year. These vulnerable patients require complex and time sensitive care to treat the causes and consequences of cardiac arrest. Delivery of excellent post-ar...

Research Terms

<21+ years old><Academy><Accident and Emergency department><Acute myocardial infarct><Acute myocardial infarction><Admission><Admission activity><Adult><Adult Human><Allografting><American><American Heart Association><Apoplexy><Asystole><Attention><Authorship><Brain Vascular Accident><Cardiac Arrest><Cardiopulmonary Resuscitation><Care Givers><Caregivers><Caring><Case Report Form><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Cessation of life><Clinical><Clinical Trials><Clinical Trials Data Monitoring Committees><Complex><Costs and Benefits><Critical Care><Critical Illness><Critically Ill><Data><Data Monitoring Committees><Data and Safety Monitoring Boards><Death><Development><Disclosure><Disease><Disorder><Emergency Department><Emergency room><Enrollment><Ensure><Environment><Family><Future><Health Care Facility><Health Facilities><Health Policy><Health system><Heart Arrest><Heterogeneity><Hospital Admission><Hospitalization><Hospitals><IRB><IRBs><Information Disclosure><Informed Consent><Institutional Review Boards><International><Intervention><Knowledge><Manuals><Medical><Medicine><Organ Donations><Outcome><P50 Mechanism><P50 Program><Patient Care><Patient Care Delivery><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Pennsylvania><Predicting Risk><Probability><Process><Provider><Public Health><Public Policy><Randomization trial><Randomized><Randomized, Controlled Trials><Recommendation><Recovery><Recovery of Function><Research Design><Research Resources><Resources><Risk Adjustment><Safety Monitoring Boards><Services><Societies><Source><Specialized Center><Specialty><Stroke><Study Type><Syndrome><System><Systems Development><Testing><Time><Tissue Donations><Trauma><Variant><Variation><adulthood><brain attack><cardiac resuscitation><care as usual><care facilities><care for patients><care of patients><care outcomes><care services><care systems><caring for patients><cerebral vascular accident><cerebrovascular accident><clinical practice><community consultation><cost><data dictionary><design><designing><development policy><developmental><enroll><experience><forecasting risk><functional outcomes><functional recovery><future implementation><health care outcomes><health care policy><heart resuscitation><hospital care><improved><medical specialties><operation><operations><out-of-hospital cardiac arrest><out-of-hospital sudden cardiac arrest><patient oriented outcomes><patient population><phase 2 trial><phase II trial><predict risk><predict risks><predicted risk><predicted risks><predicting risks><predictive risk><predicts risk><preference><primary outcome><randomisation><randomization><randomized control trial><randomized trial><randomly assigned><risk prediction><risk predictions><secondary analysis><stroked><strokes><study design><tertiary care><treatment as usual><trial comparing><trial enrollment><usual care>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Francis X. Guyette

UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PITTSBURGH, PA

Exploratory lead · 34/100
Large award
Active award
$2,394,542
FY 2025

Project Title

The effect of SPecialty cAre on Recovery from Cardiac arrest (the SPARC trial)

Grant Number:

1R61HL175113-01A1

Activity Code:

R61

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/1/2025

End Date:

8/31/2026

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Abstract Cardiac arrest is common and deadly. Over 150,000 Americans are admitted to the hospital after resuscitation from cardiac arrest each year. These vulnerable patients require complex and time sensitive care to treat the causes and consequences of cardiac arrest. Delivery of excellent post-ar...

Research Terms

<21+ years old><Academy><Accident and Emergency department><Acute myocardial infarct><Acute myocardial infarction><Admission><Admission activity><Adult><Adult Human><Allografting><American><American Heart Association><Apoplexy><Asystole><Attention><Authorship><Brain Vascular Accident><Cardiac Arrest><Cardiopulmonary Resuscitation><Care Givers><Caregivers><Caring><Case Report Form><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Cessation of life><Clinical><Clinical Trials><Clinical Trials Data Monitoring Committees><Complex><Costs and Benefits><Critical Care><Critical Illness><Critically Ill><Data><Data Monitoring Committees><Data and Safety Monitoring Boards><Death><Development><Disclosure><Disease><Disorder><Emergency Department><Emergency room><Enrollment><Ensure><Environment><Family><Future><Health Care Facility><Health Facilities><Health Policy><Health system><Heart Arrest><Heterogeneity><Hospital Admission><Hospitalization><Hospitals><IRB><IRBs><Information Disclosure><Informed Consent><Institutional Review Boards><International><Intervention><Knowledge><Manuals><Medical><Medicine><Organ Donations><Outcome><P50 Mechanism><P50 Program><Patient Care><Patient Care Delivery><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Pennsylvania><Predicting Risk><Probability><Process><Provider><Public Health><Public Policy><Randomization trial><Randomized><Randomized, Controlled Trials><Recommendation><Recovery><Recovery of Function><Research Design><Research Resources><Resources><Risk Adjustment><Safety Monitoring Boards><Services><Societies><Source><Specialized Center><Specialty><Stroke><Study Type><Syndrome><System><Systems Development><Testing><Time><Tissue Donations><Trauma><Variant><Variation><adulthood><brain attack><cardiac resuscitation><care as usual><care facilities><care for patients><care of patients><care outcomes><care services><care systems><caring for patients><cerebral vascular accident><cerebrovascular accident><clinical practice><community consultation><cost><data dictionary><design><designing><development policy><developmental><enroll><experience><forecasting risk><functional outcomes><functional recovery><future implementation><health care outcomes><health care policy><heart resuscitation><hospital care><improved><medical specialties><operation><operations><out-of-hospital cardiac arrest><out-of-hospital sudden cardiac arrest><patient oriented outcomes><patient population><phase 2 trial><phase II trial><predict risk><predict risks><predicted risk><predicted risks><predicting risks><predictive risk><predicts risk><preference><primary outcome><randomisation><randomization><randomized control trial><randomized trial><randomly assigned><risk prediction><risk predictions><secondary analysis><stroked><strokes><study design><tertiary care><treatment as usual><trial comparing><trial enrollment><usual care>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Charity G Patterson (Moore)

UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PITTSBURGH, PA

Exploratory lead · 34/100
Large award
Active award
$2,394,542
FY 2025

Project Title

The effect of SPecialty cAre on Recovery from Cardiac arrest (the SPARC trial)

Grant Number:

1R61HL175113-01A1

Activity Code:

R61

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/1/2025

End Date:

8/31/2026

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Abstract Cardiac arrest is common and deadly. Over 150,000 Americans are admitted to the hospital after resuscitation from cardiac arrest each year. These vulnerable patients require complex and time sensitive care to treat the causes and consequences of cardiac arrest. Delivery of excellent post-ar...

Research Terms

<21+ years old><Academy><Accident and Emergency department><Acute myocardial infarct><Acute myocardial infarction><Admission><Admission activity><Adult><Adult Human><Allografting><American><American Heart Association><Apoplexy><Asystole><Attention><Authorship><Brain Vascular Accident><Cardiac Arrest><Cardiopulmonary Resuscitation><Care Givers><Caregivers><Caring><Case Report Form><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Cessation of life><Clinical><Clinical Trials><Clinical Trials Data Monitoring Committees><Complex><Costs and Benefits><Critical Care><Critical Illness><Critically Ill><Data><Data Monitoring Committees><Data and Safety Monitoring Boards><Death><Development><Disclosure><Disease><Disorder><Emergency Department><Emergency room><Enrollment><Ensure><Environment><Family><Future><Health Care Facility><Health Facilities><Health Policy><Health system><Heart Arrest><Heterogeneity><Hospital Admission><Hospitalization><Hospitals><IRB><IRBs><Information Disclosure><Informed Consent><Institutional Review Boards><International><Intervention><Knowledge><Manuals><Medical><Medicine><Organ Donations><Outcome><P50 Mechanism><P50 Program><Patient Care><Patient Care Delivery><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Pennsylvania><Predicting Risk><Probability><Process><Provider><Public Health><Public Policy><Randomization trial><Randomized><Randomized, Controlled Trials><Recommendation><Recovery><Recovery of Function><Research Design><Research Resources><Resources><Risk Adjustment><Safety Monitoring Boards><Services><Societies><Source><Specialized Center><Specialty><Stroke><Study Type><Syndrome><System><Systems Development><Testing><Time><Tissue Donations><Trauma><Variant><Variation><adulthood><brain attack><cardiac resuscitation><care as usual><care facilities><care for patients><care of patients><care outcomes><care services><care systems><caring for patients><cerebral vascular accident><cerebrovascular accident><clinical practice><community consultation><cost><data dictionary><design><designing><development policy><developmental><enroll><experience><forecasting risk><functional outcomes><functional recovery><future implementation><health care outcomes><health care policy><heart resuscitation><hospital care><improved><medical specialties><operation><operations><out-of-hospital cardiac arrest><out-of-hospital sudden cardiac arrest><patient oriented outcomes><patient population><phase 2 trial><phase II trial><predict risk><predict risks><predicted risk><predicted risks><predicting risks><predictive risk><predicts risk><preference><primary outcome><randomisation><randomization><randomized control trial><randomized trial><randomly assigned><risk prediction><risk predictions><secondary analysis><stroked><strokes><study design><tertiary care><treatment as usual><trial comparing><trial enrollment><usual care>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

JAMBOOR K. VISHWANATHA

UNIVERSITY OF NORTH TEXAS HLTH SCI CTR, FORT WORTH, TX

Exploratory lead · 34/100
Large award
Active award
$2,000,000
FY 2025

Project Title

Texas Center for Health Disparities (TCHD)

Grant Number:

5S21MD012472-08

Activity Code:

S21

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

9/14/2017

End Date:

5/31/2028

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.

Project Abstract

The long-term objective of the Texas Center for Health Disparities (TCHD) is to expand the capacity of University of North Texas Health Science Center (UNTHSC) to enhance research and research training in health disparities by increasing the number of faculty and students in health disparity researc...

Research Terms

<AIDS Virus><Acquired Immune Deficiency Syndrome Virus><Acquired Immunodeficiency Syndrome Virus><Address><Affect><Apoplexy><Area><Awareness><Behavioral><Behavioral Research><Biomedical Research><Brain Vascular Accident><Cancers><Cardiovascular Diseases><Caring><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Chronic Disease><Chronic Illness><Clinical Research><Clinical Study><Collaborations><Curriculum><Diabetes Mellitus><Disease><Disorder><Disparities><Disparity><Doctor of Philosophy><Economic Income><Economical Income><Education><Education and Outreach><Educational Curriculum><Educational aspects><Endowment><Ensure><Faculty><Faculty Education><Faculty Training><Fellowship><Funding><Funding Mechanisms><Goals><HIV><Health><Health Care Professional><Health Disparities Research><Health Instruction><Health Professional><Health Sciences><Health Tutoring><Health disparities related research><Health education><Human><Human Immunodeficiency Viruses><Human Resources><Hypertension><Income><Individual><Infrastructure><Institution><Instruction and Outreach><Interdisciplinary Research><Interdisciplinary Study><Investigators><LAV-HTLV-III><Leadership><Learning><Lymphadenopathy-Associated Virus><Malignant Neoplasms><Malignant Tumor><Manpower><Medical><Mentors><Modeling><Modern Man><Multidisciplinary Collaboration><Multidisciplinary Research><NCMHD><NIMHD><National Center on Minority Health and Health Disparities><National Institute of Minority Health and Health Disparities><National Institute on Minority Health and Health Disparities><P50 Mechanism><P50 Program><Participant><Ph D student><Ph D. student><Ph. D. student><Ph.D student><Ph.D.><Ph.D. student><PhD><PhD student><PhD. student><Physicians><Population><Program Development><Program Sustainabilities><Program Sustainability><R-Series Research Projects><R01 Mechanism><R01 Program><Research><Research Grants><Research Personnel><Research Project Grants><Research Projects><Research Training><Researchers><Scholarship><Scientific Advances and Accomplishments><Scientist><Secure><Societies><Specialized Center><Stroke><Students><Teacher Education><Teacher Educator><Teacher Preparation><Teacher Professional Development><Teacher Training><Texas><Training><Training and Outreach><Tutoring and Outreach><Universities><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Virus-HIV><brain attack><cardiovascular disorder><career><cerebral vascular accident><cerebrovascular accident><chronic disorder><cohort><community based organizations><community engagement><community organizations><diabetes><disparity in care><disparity in health><disparity in health care><doctoral student><engagement with communities><experience><faculty development><faculty professional development><graduate student><health care disparity><health care inequality><health care inequity><health disparities science><health disparity><health disparity community><health disparity group><health disparity populations><high blood pressure><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><improved><incomes><innovate><innovation><innovative><instructor training><lesson plans><malignancy><member><neoplasm/cancer><new approaches><novel approaches><novel strategies><novel strategy><outreach><personnel><program sustainment><programs><recruit><scientific accomplishments><scientific advances><skills><stroked><strokes><teacher development><training opportunity><undergrad><undergraduate><undergraduate student>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Mark E Burkard

UNIVERSITY OF IOWA, IOWA CITY, IA

Exploratory lead · 34/100
Likely hiring
Team-scale grant
$249,938
FY 2025

Project Title

Cancer Center Support Grant

Grant Number:

3P30CA086862-25S1

Activity Code:

P30

Mechanism:

Research Centers

Agency:

NIH

Start Date:

7/14/2000

End Date:

3/31/2026

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

PROJECT SUMMARY/ABSTRACT Holden Comprehensive Cancer Center (HCCC) at the University of Iowa (UI) is the only NCI designated cancer center in the state of Iowa, a highly rural state that serves as the HCCC catchment area. The nearest Comprehensive Cancer Centers are approximately 200 miles away. The...

Research Terms

<Address><Agonist><Area><Basic Cancer Research><Basic Research><Basic Science><Biometrics><Biometry><Biostatistics><Business-Friendly Atmosphere><CCSG><Cancer Burden><Cancer Cause><Cancer Center><Cancer Center Support Grant><Cancer Control><Cancer Control Science><Cancer Etiology><Cancer Genes><Cancer Research Infrastructure><Cancer Treatment><Cancer-Promoting Gene><Cancers><Catchment Area><Clinic><Clinical><Clinical Investigator><Clinical Protocols><Clinical Research><Clinical Services><Clinical Study><Clinical Trials><Collaborations><Communications Media><Communities><Community Outreach><Comprehensive Cancer Center><DNA Damage Repair><DNA Repair><Diagnostic><Disparities><Disparity><Dose><Education><Educational aspects><Environment><Epidemiologic Research><Epidemiologic Studies><Epidemiological Studies><Epidemiology Research><Evaluation><Experimental Therapies><Flow Cytofluorometries><Flow Cytofluorometry><Flow Cytometry><Flow Microfluorimetry><Flow Microfluorometry><Forms of Communication><Free Radicals><Funding><Genomics><Germinoblastic Sarcoma><Germinoblastoma><Goals><Grant><HPV Vaccination><High Throughput Assay><Holden Comprehensive Cancer Center at the University of Iowa><Human Papilloma Virus Vaccination><Human Papillomavirus Vaccination><Image><Infrastructure><Institution><Intermediary Metabolism><Investigational Therapies><Investigational Treatments><Investigators><Iowa><Laboratories><Lymphoma><Malignant Lymphoma><Malignant Neoplasm Therapy><Malignant Neoplasm Treatment><Malignant Neoplasms><Malignant Tumor><Measures><Metabolic Processes><Metabolism><Microscopy><Mission><Molecular Epidemiology><Monitor><Morbidity><Morbidity - disease rate><NCI-Designated Cancer Center><National Cancer Burden><Obesity><Oncogenes><Pain><Painful><Pathway interactions><Peer Review><Persons><Population Research><Population Sciences><Population-based research><Population-level research><Process><Protocol><Protocols documentation><Publications><Publishing><Radiation><Research><Research Infrastructure><Research Personnel><Research Resources><Research Support><Researchers><Resource Sharing><Resources><Reticulolymphosarcoma><Rural><Science><Scientific Advances and Accomplishments><Scientific Publication><Scientist><Specialized Program of Research Excellence><Structure><TLR9 gene><TLR9 protein><TLR9 receptor><Teen><Teenagers><Testing><Training><Transforming Genes><Translating><Translational Research><Translational Science><Universities><Unscheduled DNA Synthesis><Viral Vector><adiposity><anti-cancer research><anti-cancer therapy><ascorbate><business-friendly environment><cancer epidemiology><cancer prevention><cancer research><cancer therapy><cancer-directed therapy><career><clinical practice><collaborative atmosphere><collaborative environment><college><collegiate><community advisory board><community advisory committee><community advisory panel><community engagement><conference><convention><corpulence><design><designing><early clinical trial><early phase clinical trial><engagement with communities><epidemiologic investigation><epidemiology study><evidence base><experimental therapeutic agents><experimental therapeutics><flow cytophotometry><fundamental research><high throughput screening><imaging><improved><innovate><innovation><innovative><interactive atmosphere><interactive environment><interdisciplinary atmosphere><interdisciplinary collaboration><interdisciplinary environment><malignancy><meeting><meetings><member><mortality><neoplasm/cancer><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><notch><notch protein><notch receptors><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><pathway><peer-group atmosphere><peer-group environment><pharmacologic><population based><programs><protocol development><recruit><rural locality><rural place><rural setting><rurality><scientific accomplishments><scientific advances><summit><symposia><symposium><teen years><teenage><theranostics><toll-like receptor 9><transdisciplinary collaboration><translation research><translational investigation>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Frank Porreca

UNIVERSITY OF ARIZONA, TUCSON, AZ

Exploratory lead · 34/100
Training-friendly
Active award
$134,905
FY 2026

Project Title

High School Student NeuroResearch Program (HSNRP)

Grant Number:

5R25NS076437-13

Activity Code:

R25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

8/1/2011

End Date:

11/30/2027

Why this may be worth a closer look

  • • Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

University of Arizona's High School Student NeuroResearch (NR) Program (HSNRP) nurtures, trains, and sustains the spirit of inquiry in a growing diverse, connected workforce pipeline and faculty peer/near peer support network. Over the next 5 years, HSNRP will offer annually 10 talented, motivated A...

Research Terms

<AD dementia><Alum Adjuvant><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimers Dementia><Apoplexy><Arizona><Basic Research><Basic Science><Biomedical Research><Blood - brain barrier anatomy><Blood-Brain Barrier><Body System><Brain><Brain Neoplasia><Brain Neoplasms><Brain Nervous System><Brain Trauma><Brain Tumors><Brain Vascular Accident><Cell Phone><Cellular Phone><Cellular Telephone><Cephalalgia><Cephalgia><Cephalodynia><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Cerebrum><Clinical><Clinical Research><Clinical Study><Cognition><Collaborations><Communications Media><Communities><Complex><Computer software><Cranial Pain><Creativeness><Curiosities><Curriculum><Data Bases><Databases><Deep Brain Stimulation><Disadvantaged><Disease><Disorder><Educational Curriculum><Educational process of instructing><Encephalon><Epilepsy><Epileptic Seizures><Epileptics><Equilibrium><Evaluation><Exhibits><Faculty><Fear><Feedback><Forms of Communication><Fright><Funding><Future><Goals><Habits><Head Pain><Headache><Health><Hemato-Encephalic Barrier><High School Student><Hybrids><Hydrocephalus><Hydrocephaly><In Situ><In Vitro><Individual><Infrastructure><Institution><Interdisciplinary Research><Interdisciplinary Study><International><Investigators><Knowledge><Laboratories><Language><Leadership><Life><Link><Long-term Follow-up><Lymphovascular><MD students><Medical><Medical Students><Medicine><Medulla Spinalis><Mentors><Mind><Mission><Mobile Phones><Modeling><Molecular><Monitor><Multidisciplinary Collaboration><Multidisciplinary Research><Multimedia><Multimedium><Muscular Dystrophies><Myodystrophica><Myodystrophy><NIH><NINDS><National Institute of Neurological Diseases and Stroke><National Institute of Neurological Disorders and Stroke><National Institutes of Health><Nervous System><Nervous System Diseases><Nervous System Disorder><Neuranatomies><Neuranatomy><Neuroanatomies><Neuroanatomy><Neurobiology><Neurologic Body System><Neurologic Disorders><Neurologic Organ System><Neurological Disorders><Neurosciences><Organ><Organ System><P50 Mechanism><P50 Program><Pain><Painful><Paralysis Agitans><Parkinson><Parkinson Disease><Periodicals><Peripheral Nervous System><Pharmacology><Physiology><Population Research><Population-based research><Population-level research><Primary Parkinsonism><Primary Senile Degenerative Dementia><Productivity><Proteomics><Psychiatry><Reaction><Registries><Research><Research Personnel><Researchers><Science><Secondary School Student><Secondary Student><Seizure Disorder><Sleep disturbances><Social Network><Software><Specialized Center><Specialty><Spinal Cord><Strategic Planning><Stroke><Students><Survey Instrument><Surveys><Talents><Teaching><Training><Training Programs><Translating><Translation Process><Translational Research><Translational Science><Translations><Traumatic Brain Injury><Underrepresented Ethnic Minority><Underrepresented Minority><United States National Institutes of Health><Universities><Vocabulary><Vocabulary Words><aberrant sleep><addiction><addictive disorder><alum><aluminum sulfate><balance><balance function><bench bed side><bench bedside><bench to bed side><bench to bedside><bench to clinic><bench to clinical practice><bloodbrain barrier><brain abnormalities><brain attack><career><cerebral><cerebral vascular accident><cerebrovascular accident><community engagement><creativity><data base><design><designing><disparity in health><disrupted sleep><disturbed sleep><engagement with communities><epilepsia><epileptogenic><experience><head ache><health disparity><health literacy><high school><high schoolers><hydrocephalic><iPhone><impaired sleep><improved><in silico><in vivo><innovate><innovation><innovative><interest><investigate population><irregular sleep><lesson plans><literacy><long-term followup><medical school students><medical specialties><multidisciplinary><muscle dystrophy><neural imaging><neuro-imaging><neurobiological><neurogenomics><neuroimaging><neurological disease><neurological imaging><neuroprotection><neuroprotective><novel><peer><peer networks><peer support><periodic><periodical><population investigation><population level investigation><population specific research><primary degenerative dementia><programs><recruit><retention rate><retention strategy><role model><senile dementia of the Alzheimer type><skills><sleep disruption><sleep dysregulation><sleep/wake disruption><sleep/wake disturbance><smart phone><smartphone><stroked><strokes><student engagement><student motivation><student participation><studies of populations><study of the population><study population><summer institute><summer research><summer student><summer undergraduate training><support network><survey population><translation><translation research><translational investigation><traumatic brain damage><tumors in the brain><under-representation of minorities><under-represented minority><undergrad><undergraduate><undergraduate student><undergraduate summer program><undergraduate summer research><underrepresentation of minorities><virtual>
View Full Project Details on NIH Reporter
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MARLYS Hearst WITTE

UNIVERSITY OF ARIZONA, TUCSON, AZ

Exploratory lead · 34/100
Training-friendly
Active award
$134,905
FY 2026

Project Title

High School Student NeuroResearch Program (HSNRP)

Grant Number:

5R25NS076437-13

Activity Code:

R25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

8/1/2011

End Date:

11/30/2027

Why this may be worth a closer look

  • • Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

University of Arizona's High School Student NeuroResearch (NR) Program (HSNRP) nurtures, trains, and sustains the spirit of inquiry in a growing diverse, connected workforce pipeline and faculty peer/near peer support network. Over the next 5 years, HSNRP will offer annually 10 talented, motivated A...

Research Terms

<AD dementia><Alum Adjuvant><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimers Dementia><Apoplexy><Arizona><Basic Research><Basic Science><Biomedical Research><Blood - brain barrier anatomy><Blood-Brain Barrier><Body System><Brain><Brain Neoplasia><Brain Neoplasms><Brain Nervous System><Brain Trauma><Brain Tumors><Brain Vascular Accident><Cell Phone><Cellular Phone><Cellular Telephone><Cephalalgia><Cephalgia><Cephalodynia><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Cerebrum><Clinical><Clinical Research><Clinical Study><Cognition><Collaborations><Communications Media><Communities><Complex><Computer software><Cranial Pain><Creativeness><Curiosities><Curriculum><Data Bases><Databases><Deep Brain Stimulation><Disadvantaged><Disease><Disorder><Educational Curriculum><Educational process of instructing><Encephalon><Epilepsy><Epileptic Seizures><Epileptics><Equilibrium><Evaluation><Exhibits><Faculty><Fear><Feedback><Forms of Communication><Fright><Funding><Future><Goals><Habits><Head Pain><Headache><Health><Hemato-Encephalic Barrier><High School Student><Hybrids><Hydrocephalus><Hydrocephaly><In Situ><In Vitro><Individual><Infrastructure><Institution><Interdisciplinary Research><Interdisciplinary Study><International><Investigators><Knowledge><Laboratories><Language><Leadership><Life><Link><Long-term Follow-up><Lymphovascular><MD students><Medical><Medical Students><Medicine><Medulla Spinalis><Mentors><Mind><Mission><Mobile Phones><Modeling><Molecular><Monitor><Multidisciplinary Collaboration><Multidisciplinary Research><Multimedia><Multimedium><Muscular Dystrophies><Myodystrophica><Myodystrophy><NIH><NINDS><National Institute of Neurological Diseases and Stroke><National Institute of Neurological Disorders and Stroke><National Institutes of Health><Nervous System><Nervous System Diseases><Nervous System Disorder><Neuranatomies><Neuranatomy><Neuroanatomies><Neuroanatomy><Neurobiology><Neurologic Body System><Neurologic Disorders><Neurologic Organ System><Neurological Disorders><Neurosciences><Organ><Organ System><P50 Mechanism><P50 Program><Pain><Painful><Paralysis Agitans><Parkinson><Parkinson Disease><Periodicals><Peripheral Nervous System><Pharmacology><Physiology><Population Research><Population-based research><Population-level research><Primary Parkinsonism><Primary Senile Degenerative Dementia><Productivity><Proteomics><Psychiatry><Reaction><Registries><Research><Research Personnel><Researchers><Science><Secondary School Student><Secondary Student><Seizure Disorder><Sleep disturbances><Social Network><Software><Specialized Center><Specialty><Spinal Cord><Strategic Planning><Stroke><Students><Survey Instrument><Surveys><Talents><Teaching><Training><Training Programs><Translating><Translation Process><Translational Research><Translational Science><Translations><Traumatic Brain Injury><Underrepresented Ethnic Minority><Underrepresented Minority><United States National Institutes of Health><Universities><Vocabulary><Vocabulary Words><aberrant sleep><addiction><addictive disorder><alum><aluminum sulfate><balance><balance function><bench bed side><bench bedside><bench to bed side><bench to bedside><bench to clinic><bench to clinical practice><bloodbrain barrier><brain abnormalities><brain attack><career><cerebral><cerebral vascular accident><cerebrovascular accident><community engagement><creativity><data base><design><designing><disparity in health><disrupted sleep><disturbed sleep><engagement with communities><epilepsia><epileptogenic><experience><head ache><health disparity><health literacy><high school><high schoolers><hydrocephalic><iPhone><impaired sleep><improved><in silico><in vivo><innovate><innovation><innovative><interest><investigate population><irregular sleep><lesson plans><literacy><long-term followup><medical school students><medical specialties><multidisciplinary><muscle dystrophy><neural imaging><neuro-imaging><neurobiological><neurogenomics><neuroimaging><neurological disease><neurological imaging><neuroprotection><neuroprotective><novel><peer><peer networks><peer support><periodic><periodical><population investigation><population level investigation><population specific research><primary degenerative dementia><programs><recruit><retention rate><retention strategy><role model><senile dementia of the Alzheimer type><skills><sleep disruption><sleep dysregulation><sleep/wake disruption><sleep/wake disturbance><smart phone><smartphone><stroked><strokes><student engagement><student motivation><student participation><studies of populations><study of the population><study population><summer institute><summer research><summer student><summer undergraduate training><support network><survey population><translation><translation research><translational investigation><traumatic brain damage><tumors in the brain><under-representation of minorities><under-represented minority><undergrad><undergraduate><undergraduate student><undergraduate summer program><undergraduate summer research><underrepresentation of minorities><virtual>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Russell S Witte

UNIVERSITY OF ARIZONA, TUCSON, AZ

Exploratory lead · 34/100
Training-friendly
Active award
$134,905
FY 2026

Project Title

High School Student NeuroResearch Program (HSNRP)

Grant Number:

5R25NS076437-13

Activity Code:

R25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

8/1/2011

End Date:

11/30/2027

Why this may be worth a closer look

  • • Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

University of Arizona's High School Student NeuroResearch (NR) Program (HSNRP) nurtures, trains, and sustains the spirit of inquiry in a growing diverse, connected workforce pipeline and faculty peer/near peer support network. Over the next 5 years, HSNRP will offer annually 10 talented, motivated A...

Research Terms

<AD dementia><Alum Adjuvant><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimers Dementia><Apoplexy><Arizona><Basic Research><Basic Science><Biomedical Research><Blood - brain barrier anatomy><Blood-Brain Barrier><Body System><Brain><Brain Neoplasia><Brain Neoplasms><Brain Nervous System><Brain Trauma><Brain Tumors><Brain Vascular Accident><Cell Phone><Cellular Phone><Cellular Telephone><Cephalalgia><Cephalgia><Cephalodynia><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Cerebrum><Clinical><Clinical Research><Clinical Study><Cognition><Collaborations><Communications Media><Communities><Complex><Computer software><Cranial Pain><Creativeness><Curiosities><Curriculum><Data Bases><Databases><Deep Brain Stimulation><Disadvantaged><Disease><Disorder><Educational Curriculum><Educational process of instructing><Encephalon><Epilepsy><Epileptic Seizures><Epileptics><Equilibrium><Evaluation><Exhibits><Faculty><Fear><Feedback><Forms of Communication><Fright><Funding><Future><Goals><Habits><Head Pain><Headache><Health><Hemato-Encephalic Barrier><High School Student><Hybrids><Hydrocephalus><Hydrocephaly><In Situ><In Vitro><Individual><Infrastructure><Institution><Interdisciplinary Research><Interdisciplinary Study><International><Investigators><Knowledge><Laboratories><Language><Leadership><Life><Link><Long-term Follow-up><Lymphovascular><MD students><Medical><Medical Students><Medicine><Medulla Spinalis><Mentors><Mind><Mission><Mobile Phones><Modeling><Molecular><Monitor><Multidisciplinary Collaboration><Multidisciplinary Research><Multimedia><Multimedium><Muscular Dystrophies><Myodystrophica><Myodystrophy><NIH><NINDS><National Institute of Neurological Diseases and Stroke><National Institute of Neurological Disorders and Stroke><National Institutes of Health><Nervous System><Nervous System Diseases><Nervous System Disorder><Neuranatomies><Neuranatomy><Neuroanatomies><Neuroanatomy><Neurobiology><Neurologic Body System><Neurologic Disorders><Neurologic Organ System><Neurological Disorders><Neurosciences><Organ><Organ System><P50 Mechanism><P50 Program><Pain><Painful><Paralysis Agitans><Parkinson><Parkinson Disease><Periodicals><Peripheral Nervous System><Pharmacology><Physiology><Population Research><Population-based research><Population-level research><Primary Parkinsonism><Primary Senile Degenerative Dementia><Productivity><Proteomics><Psychiatry><Reaction><Registries><Research><Research Personnel><Researchers><Science><Secondary School Student><Secondary Student><Seizure Disorder><Sleep disturbances><Social Network><Software><Specialized Center><Specialty><Spinal Cord><Strategic Planning><Stroke><Students><Survey Instrument><Surveys><Talents><Teaching><Training><Training Programs><Translating><Translation Process><Translational Research><Translational Science><Translations><Traumatic Brain Injury><Underrepresented Ethnic Minority><Underrepresented Minority><United States National Institutes of Health><Universities><Vocabulary><Vocabulary Words><aberrant sleep><addiction><addictive disorder><alum><aluminum sulfate><balance><balance function><bench bed side><bench bedside><bench to bed side><bench to bedside><bench to clinic><bench to clinical practice><bloodbrain barrier><brain abnormalities><brain attack><career><cerebral><cerebral vascular accident><cerebrovascular accident><community engagement><creativity><data base><design><designing><disparity in health><disrupted sleep><disturbed sleep><engagement with communities><epilepsia><epileptogenic><experience><head ache><health disparity><health literacy><high school><high schoolers><hydrocephalic><iPhone><impaired sleep><improved><in silico><in vivo><innovate><innovation><innovative><interest><investigate population><irregular sleep><lesson plans><literacy><long-term followup><medical school students><medical specialties><multidisciplinary><muscle dystrophy><neural imaging><neuro-imaging><neurobiological><neurogenomics><neuroimaging><neurological disease><neurological imaging><neuroprotection><neuroprotective><novel><peer><peer networks><peer support><periodic><periodical><population investigation><population level investigation><population specific research><primary degenerative dementia><programs><recruit><retention rate><retention strategy><role model><senile dementia of the Alzheimer type><skills><sleep disruption><sleep dysregulation><sleep/wake disruption><sleep/wake disturbance><smart phone><smartphone><stroked><strokes><student engagement><student motivation><student participation><studies of populations><study of the population><study population><summer institute><summer research><summer student><summer undergraduate training><support network><survey population><translation><translation research><translational investigation><traumatic brain damage><tumors in the brain><under-representation of minorities><under-represented minority><undergrad><undergraduate><undergraduate student><undergraduate summer program><undergraduate summer research><underrepresentation of minorities><virtual>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Vanessa Salazar

CLEVELAND CLINIC LERNER COM-CWRU, CLEVELAND, OH

Exploratory lead · 34/100
Training-friendly
Active award
$55,114
FY 2026

Project Title

Host and microbe-dependent mechanisms of enhanced autoimmune susceptibility driven by checkpoint inhibitors

Grant Number:

5F31AI174784-03

Activity Code:

F31

Mechanism:

Training, Individual

Agency:

NIH

Start Date:

12/1/2023

End Date:

11/30/2026

Why this may be worth a closer look

  • • Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

Project Summary Immune checkpoint inhibitor therapy has drastically improved the prognosis of patients with several advanced- stage cancers that were initially considered terminal. However, the increased use of checkpoint inhibitors has resulted in the common emergence of immune-related adverse even...

Research Terms

<7S Gamma Globulin><Abdomen><Aging><Antibodies><Antitumor Response><Apoptosis><Apoptosis Pathway><Autoimmune><Autoimmune Diseases><Autoimmune Status><Autoimmunity><Automobile Driving><Autoregulation><B blood cells><B cell><B cells><B-Cell Activation><B-Cells><B-Lymphocytes><B-cell><Bacteria><Biologic Models><Biological Models><Body Tissues><Bp50><CD19><CD19 gene><CD3><CD3 Antigens><CD3 Complex><CD3 molecule><CD40><CDW40><CT-26><CT26><Cancers><Cell Body><Cell Communication and Signaling><Cell Signaling><Cell-Mediated Lympholytic Cells><Cells><Checkpoint inhibitor><Chronic><Clinical><Clinical Trials><Clinical genetics><Colon Adenocarcinoma><Colonic Adenocarcinoma><Combined Modality Therapy><Control Groups><Cytolytic T-Cell><Cytotoxic T Cell><Cytotoxic T-Lymphocytes><Data><Deposit><Deposition><Development><Disease><Disorder><Evaluation><Exclusion><Fats><Fatty acid glycerol esters><Foundations><GI microbiota><Gastrointestinal microbiota><Generations><Genetic><Genetic Predisposition><Genetic Predisposition to Disease><Genetic Screening><Genetic Susceptibility><Genetic propensity><Germ-Free><Goals><Greater sac of peritoneum><Histologic><Histologically><Homeostasis><Human><IgG><Immune><Immune Cell Activation><Immune checkpoint inhibitor><Immune infiltrates><Immune system><Immunes><Immunochemical Immunologic><Immunoglobulin G><Immunologic><Immunological><Immunologically><Immunologics><Impairment><Incidence><Individual><Infiltration><Inherited Predisposition><Inherited Susceptibility><Intestinal><Intestines><Intracellular Communication and Signaling><LD Antigens><Lead><Life><Link><Lupus Erythematosus Disseminatus><Lymphocyte antigen><MGC9013><Malignant Neoplasms><Malignant Tumor><Mediating><Medical><Medical Genetics><Mesenteric><Mesentery><Mice><Mice Mammals><Microbe><Model System><Modeling><Modern Man><Multimodal Therapy><Multimodal Treatment><Murine><Mus><OKT3 antigen><Pancreas><Pancreatic><Patient Care><Patient Care Delivery><Patients><Pb element><Peritoneal><Peritoneal Cavity><Physiological Homeostasis><Pre-Clinical Model><Preclinical Models><Predisposition><Programmed Cell Death><Psoriasis><Risk><Role><SLE><Severities><Sicca Syndrome><Signal Transduction><Signal Transduction Systems><Signaling><Sjogren's Disease><Sjogren's Syndrome><Sjogrens><Sjögren Syndrome><Susceptibility><Systemic Lupus Erythematosus><Systemic Lupus Erythematous><Systemic Lupus Erythmatosus><T-Cells><T-Lymphocyte><T3 Antigens><T3 Complex><T3 molecule><TNFRSF5><TNFRSF5 gene><Testing><Therapeutic Uses><Tissues><Toxic effect><Toxicities><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><Wild Type Mouse><activated B cells><aged><anti-cancer immunotherapy><anti-tumor response><anticancer immunotherapy><autoimmune attack><autoimmune condition><autoimmune destruction><autoimmune disorder><autoimmune pathogenesis><autoimmune toxicity><autoimmunity disease><biological signal transduction><bowel><cancer immunotherapy><care for patients><care of patients><caring for patients><check point immunotherapy><check point inhibition><check point inhibitor therapy><check point inhibitory therapy><check point therapy><checkpoint immunotherapy><checkpoint inhibition><checkpoint inhibitor therapy><checkpoint inhibitory therapy><checkpoint therapy><clinical practice><combination therapy><combined modality treatment><combined treatment><developmental><disseminated lupus erythematosus><driving><enteric microbial community><enteric microbiota><experiment><experimental research><experimental study><experiments><gastrointestinal microbial flora><genetic vulnerability><genetically predisposed><germ free condition><gut community><gut flora><gut microbe community><gut microbes><gut microbial community><gut microbial composition><gut microbial consortia><gut microbial species><gut microbiota><gut microbiotic><gut microflora><heavy metal Pb><heavy metal lead><immune activation><immune cell infiltrate><immune check point inhibition><immune check point inhibitor><immune check point therapy><immune checkpoint inhibition><immune checkpoint therapy><immune-based cancer therapies><immune-mediated adverse events><immune-related adverse effect><immune-related adverse events><immune-related adverse reaction><immunopathology><immunotherapy for cancer><immunotherapy of cancer><improved><intestinal flora><intestinal microbes><intestinal microbiota><intestinal microflora><intestinal tract microflora><killer T cell><lymphocyte differentiation antigen><malignancy><member><microbial consortia><microbial flora><microbiome><microbiome components><microbiome members><microbiota><microbiota community><microflora><mouse model><multi-modal therapy><multi-modal treatment><multispecies consortia><murine model><neoplasm/cancer><non-synonymous mutation><nonsynonymous mutation><nonsynonymous single nucleotide polymorphism><nonsynonymous single nucleotide variant><nonsynonymous single-nucleotide substitution><nonsynonymous variant><p50><patient population><patient prognosis><permissiveness><psoriasiform><psoriatic><response><social role><specific pathogen free><success><systemic lupus erythematosis><thymus derived lymphocyte><tumor><wildtype mouse><xerodermosteosis>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Akash Mishra

HOFSTRA UNIVERSITY, HEMPSTEAD, NY

Exploratory lead · 34/100
Training-friendly
Active award
$42,538
FY 2026

Project Title

Determining neural dynamics of human memory using invasive recordings and closed-loop electrical brain stimulation

Grant Number:

5F30MH139332-02

Activity Code:

F30

Mechanism:

Training, Individual

Agency:

NIH

Start Date:

12/3/2024

End Date:

12/2/2029

Why this may be worth a closer look

  • • Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

PROJECT SUMMARY One of the most detrimental afflictions of the human condition is the inability to create or recall memories. As our population ages and the prevalence of neurodegenerative diseases increases, the burden of memory impairment is expected to surge. Hence, it is critical to develop nove...

Research Terms

<Age><Ammon Horn><Behavior><Behavioral><Biological Markers><Brain><Brain Nervous System><Cell Communication and Signaling><Cell Signaling><Clinical><Cognitive Retention Disorders><Cornu Ammonis><Coupled><Cyclicity><Data><Degenerative Neurologic Disorders><Development><Devices><Electrical Stimulation of the Brain><Electrodes><Electrophysiology><Electrophysiology (science)><Encephalon><Epilepsy><Epileptic Seizures><Epileptics><Episodic memory><Family><Foundations><Frequencies><Goals><Hippocampus><Human><Implanted Electrodes><Intervention><Intracellular Communication and Signaling><Intractable Epilepsy><Knowledge><Literature><Location><Measures><Memory><Memory Deficit><Memory Disorders><Memory impairment><Methodology><Middle Temporal Gyrus><Modality><Modern Man><Neocortex><Nerve Cells><Nerve Unit><Nervous System Degenerative Diseases><Neural Cell><Neural Degenerative Diseases><Neural degenerative Disorders><Neurocyte><Neurodegenerative Diseases><Neurodegenerative Disorders><Neurologic><Neurologic Degenerative Conditions><Neurological><Neurons><Neurophysiology / Electrophysiology><Operative Procedures><Operative Surgical Procedures><P50 Mechanism><P50 Program><Pathologic><Patient Recruitments><Patients><Pattern><Performance><Periodicity><Phase><Physicians><Play><Population><Position><Positioning Attribute><Prevalence><Property><Public Health><Refractory epilepsy><Research><Research Proposals><Resolution><Rhythmicity><Role><Scientist><Seizure Disorder><Signal Transduction><Signal Transduction Systems><Signaling><Specialized Center><Stimulus><Structure><Structure of middle temporal gyrus><Surgical><Surgical Interventions><Surgical Procedure><Symptoms><Techniques><Training><advanced analytics><ages><alleviate symptom><ameliorating symptom><awake><bio-markers><biologic marker><biological signal transduction><biomarker><biomarker identification><career><decrease symptom><degenerative diseases of motor and sensory neurons><degenerative neurological diseases><design><designing><developmental><direct application><drug-resistant epilepsy><effective therapy><effective treatment><electrophysiological><epilepsia><epileptogenic><experience><fewer symptoms><frontal cortex><frontal lobe><high definition><high-resolution><hippocampal><homotypical cortex><identification of biomarkers><identification of new biomarkers><implantation><improved><in vivo><innovate><innovation><innovative><isocortex><marker identification><memory dysfunction><memory encoding><memory recall><memory retrieval><neocortical><neopallium><neural><neural circuit><neural circuitry><neural control><neural patterning><neural regulation><neuro-prosthetic><neurocircuitry><neurodegenerative illness><neuromodulation><neuromodulatory><neuronal><neurophysiological><neurophysiology><neuroprosthesis><neuroprosthetic><neuropsychiatric><neuropsychiatry><neuroregulation><neurosurgery><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><participant recruitment><practical implementation><pragmatic implementation><reduce symptoms><relieves symptoms><resolutions><skill acquisition><skill development><social role><spatial and temporal><spatial temporal><spatiotemporal><substantia alba><surgery><symptom alleviation><symptom reduction><symptom relief><synaptic circuit><synaptic circuitry><technological innovation><white matter>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

YONG-RUI ZOU

FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH, MANHASSET, NY

Exploratory lead · 32/100
Solid budget
Recent
Active award
$460,625
FY 2026

Project Title

Maturation and maintenance of the germinal center niche

Grant Number:

1R21AI196430-01

Activity Code:

R21

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/10/2026

End Date:

1/31/2028

Project Abstract

Project Summary/Abstract Follicular dendritic cells (FDCs) are specialized stromal cells that form clusters in B cell follicles of peripheral lymphoid organs. These FDC clusters demarcate the light zone of the germinal center (GC), where B cells that have undergone somatic hypermutation of their B ...

Research Terms

<(TNF)-α><Affinity><Antibodies><Antibody Affinity><Antibody Response><Antigens><Autoimmune Status><Autoimmunity><B blood cells><B cell><B cell receptor><B cells><B-Cell Antigen Receptor><B-Cells><B-Lymphocytes><B-cell><Back><Biological><Birth><Blocking Antibodies><Blood Plasma Cell><Cachectin><Cell Body><Cell Count><Cell Function><Cell Number><Cell Physiology><Cell Process><Cells><Cellular Function><Cellular Physiology><Cellular Process><Chronic><Clinical><Clonal Expansion><Cyclicity><Darkness><Data><Development><Disease><Disorder><Dorsum><Exhibits><Flow Cytofluorometries><Flow Cytofluorometry><Flow Cytometry><Flow Microfluorimetry><Flow Microfluorometry><Follicular Dendritic Cells><Foundations><Genes><Germ-Free><Germinal Center><Helper Cells><Helper T-Cells><Helper T-Lymphocytes><Helper-Inducer T-Cells><Helper-Inducer T-Lymphocyte><History><Ig Somatic Hypermutation><Immunization><Immunize><Immunoglobulin Somatic Hypermutation><Impairment><Increase lifespan><Inducer Cells><Inducer T-Lymphocytes><Inflammation><Inflammatory><Integrin Inhibition><Integrins><Integrins Extracellular Matrix><Intervention><Investigation><Label><Length of Life><Light><Longevity><Lupus><Lymphatic cell><Lymphocyte><Lymphocytic><Lymphotoxin><Lymphotoxin A><Lymphotoxin-alpha><Lymphotoxin-α><Macrophage-Derived TNF><Maintenance><Mediating><Member 1 TNF Superfamily><Memory B Cell><Memory B-Lymphocyte><Methods><Mice><Mice Mammals><Molecular><Monocyte-Derived TNF><Morphology><Murine><Mus><P50 Mechanism><P50 Program><Parturition><Pathway interactions><Periodicity><Photoradiation><Plasma Cells><Plasmacytes><Process><Production><Proliferating><Reaction><Receptor Gene><Recording of previous events><Research><Rhythmicity><Role><Site><Specialized Center><Spleen><Spleen Reticuloendothelial System><Stromal Cells><Structure><Structure of germinal center of lymph node><Subcellular Process><T-Cells><T-Lymphocyte><TNF><TNF A><TNF Alpha><TNF gene><TNF-b><TNF-beta><TNF-α><TNF-β><TNFA><TNFSF1><TNFα><TNFβ><Testing><Time><Tumor Necrosis Factor><Tumor Necrosis Factor-Beta><Tumor Necrosis Factor-alpha><Tumor Necrosis Factor-β><Upregulation><Vaccination><Work><aged mice><aged mouse><antigen antibody affinity><biologic><boost longevity><developmental><elderly mice><elongating the lifespan><enhance longevity><extend life span><extend lifespan><extend longevity><flow cytophotometry><foster longevity><histories><immunogen><improve lifespan><improve longevity><improved><inflammatory modulation><insight><lifespan extension><lymph cell><migration><mouse model><murine model><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><old mice><pathway><peripheral lymph organ><peripheral lymphoid organ><plasmocyte><programs><proliferation capability><proliferation capacity><proliferation potential><proliferative capability><proliferative capacity><proliferative potential><prolong lifespan><prolong longevity><promote lifespan><promote longevity><recruit><response><scRNA sequencing><scRNA-seq><single cell RNA-seq><single cell RNAseq><single cell expression profiling><single cell transcriptomic profiling><single-cell RNA sequencing><social role><somatic hypermutation><support longevity><thymus derived lymphocyte>
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Adam Mor

COLUMBIA UNIVERSITY HEALTH SCIENCES, NEW YORK, NY

Exploratory lead · 32/100
Solid budget
Recent
Active award
$452,375
FY 2026

Project Title

The role of tissue-resident T cells in osteoarthritis during the transition to inflammatory arthritis induced by immune checkpoint inhibitors

Grant Number:

1R21AI197040-01

Activity Code:

R21

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/13/2026

End Date:

1/31/2028

Project Abstract

PROJECT ABSTRACT OsteoarthriƟs (OA) is the most prevalent joint disease. Once viewed as an irreversible, age-related degeneraƟve change to carƟlage, OA is now recognized as a systemic disorder featuring a prominent inflammatory aspect in which T cells appear to play a role. However, the impact of OA ...

Research Terms

<Address><Adverse Experience><Adverse event><Affect><American><Autoimmune><Automobile Driving><Behavior><Biology><Blood><Blood Reticuloendothelial System><Body Tissues><Bp50><CD4 Cells><CD4 Positive T Lymphocytes><CD4 T cells><CD4 helper T cell><CD4 lymphocyte><CD4+ T-Lymphocyte><CD4-Positive Lymphocytes><CD40><CD8><CD8B><CD8B1><CD8B1 gene><CDW40><Cancer Patient><Cancer Treatment><Cell Body><Cell Communication><Cell Communication and Signaling><Cell Interaction><Cell Signaling><Cell-to-Cell Interaction><Cells><Checkpoint inhibitor><Chronic><Clinic><Clinical><DCLAMP><Data><Degenerative Arthritis><Degenerative polyarthritis><Development><Disease><Disorder><Drugs><Exhibits><Flow Cytofluorometries><Flow Cytofluorometry><Flow Cytometry><Flow Microfluorimetry><Flow Microfluorometry><Grips><Heterogeneity><Human><Immune><Immune Tolerance><Immune checkpoint inhibitor><Immunes><Immunologic Subtyping><Immunologic Tolerance><Immunophenotyping><Individual><Inflammation><Inflammatory><Inflammatory Arthritis><Interruption><Intracellular Communication and Signaling><Joint Diseases><Joints><LAMP3><LAMP3 gene><LYT3><Life><Ligands><Link><Liquid substance><MGC9013><Malignant Neoplasm Therapy><Malignant Neoplasm Treatment><Mechanical Stress><Mediating><Medication><Membrana Synovialis Capsulae Articularis><Memory><Modern Man><Morbidity><Non-Polyadenylated RNA><Organ><Osteoarthritis><Osteoarthrosis><PD 1><PD-1><PD1><Pathogenicity><Pathway interactions><Patients><Pharmaceutical Preparations><Phenotype><Process><Proteins><Publishing><Qualifying><RNA><RNA Gene Products><Research><Ribonucleic Acid><Role><Sampling><Signal Transduction><Signal Transduction Systems><Signaling><Survival Rate><Syndrome><Synovia><Synovial Fluid><Synovial Membrane><Synovium><T cell receptor repertoire sequencing><T cell receptor sequencing><T cell response><T-Cell Subsets><T-Cells><T-Lymphocyte><T-Lymphocyte Subsets><T4 Cells><T4 Lymphocytes><TCR repertoire sequencing><TCR sequencing><TCR-seq><TCRseq><TNFRSF5><TNFRSF5 gene><TSC403><Teff cell><Testing><Tissues><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><Visual><Visualization><age associated><age correlated><age dependent><age linked><age related><age specific><anti-cancer therapy><arthropathic><arthropathies><arthropathy><biological signal transduction><cancer therapy><cancer-directed therapy><cell type><check point immunotherapy><check point inhibitor therapy><check point inhibitory therapy><check point therapy><checkpoint immunotherapy><checkpoint inhibitor therapy><checkpoint inhibitory therapy><checkpoint therapy><degenerative joint disease><developmental><driving><drug/agent><effector T cell><experience><flow cytophotometry><fluid><gene panel><grasp><high dimensionality><hypertrophic arthritis><immune check point><immune check point inhibitor><immune check point therapy><immune checkpoint><immune checkpoint therapy><immune system tolerance><immune unresponsiveness><immune-mediated adverse events><immune-related adverse effect><immune-related adverse events><immune-related adverse reaction><immunecheckpoint><immunogenic><immunological paralysis><improved><inflamed joint><joint disorder><joint inflammation><joint swelling><liquid><lung cancer early detection><lung cancer screening><lymphoid structures><multigene panel><nanostring><p50><pathway><programmed cell death 1><programmed cell death protein 1><programmed death 1><response><restraint><scRNA sequencing><scRNA-seq><single cell RNA-seq><single cell RNAseq><single cell expression profiling><single cell transcriptomic profiling><single-cell RNA sequencing><sle2><social role><systemic lupus erythematosus susceptibility 2><thymus derived lymphocyte><transcriptomics><tumor>
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Robert J Winchester

COLUMBIA UNIVERSITY HEALTH SCIENCES, NEW YORK, NY

Exploratory lead · 32/100
Solid budget
Recent
Active award
$452,375
FY 2026

Project Title

The role of tissue-resident T cells in osteoarthritis during the transition to inflammatory arthritis induced by immune checkpoint inhibitors

Grant Number:

1R21AI197040-01

Activity Code:

R21

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/13/2026

End Date:

1/31/2028

Project Abstract

PROJECT ABSTRACT OsteoarthriƟs (OA) is the most prevalent joint disease. Once viewed as an irreversible, age-related degeneraƟve change to carƟlage, OA is now recognized as a systemic disorder featuring a prominent inflammatory aspect in which T cells appear to play a role. However, the impact of OA ...

Research Terms

<Address><Adverse Experience><Adverse event><Affect><American><Autoimmune><Automobile Driving><Behavior><Biology><Blood><Blood Reticuloendothelial System><Body Tissues><Bp50><CD4 Cells><CD4 Positive T Lymphocytes><CD4 T cells><CD4 helper T cell><CD4 lymphocyte><CD4+ T-Lymphocyte><CD4-Positive Lymphocytes><CD40><CD8><CD8B><CD8B1><CD8B1 gene><CDW40><Cancer Patient><Cancer Treatment><Cell Body><Cell Communication><Cell Communication and Signaling><Cell Interaction><Cell Signaling><Cell-to-Cell Interaction><Cells><Checkpoint inhibitor><Chronic><Clinic><Clinical><DCLAMP><Data><Degenerative Arthritis><Degenerative polyarthritis><Development><Disease><Disorder><Drugs><Exhibits><Flow Cytofluorometries><Flow Cytofluorometry><Flow Cytometry><Flow Microfluorimetry><Flow Microfluorometry><Grips><Heterogeneity><Human><Immune><Immune Tolerance><Immune checkpoint inhibitor><Immunes><Immunologic Subtyping><Immunologic Tolerance><Immunophenotyping><Individual><Inflammation><Inflammatory><Inflammatory Arthritis><Interruption><Intracellular Communication and Signaling><Joint Diseases><Joints><LAMP3><LAMP3 gene><LYT3><Life><Ligands><Link><Liquid substance><MGC9013><Malignant Neoplasm Therapy><Malignant Neoplasm Treatment><Mechanical Stress><Mediating><Medication><Membrana Synovialis Capsulae Articularis><Memory><Modern Man><Morbidity><Non-Polyadenylated RNA><Organ><Osteoarthritis><Osteoarthrosis><PD 1><PD-1><PD1><Pathogenicity><Pathway interactions><Patients><Pharmaceutical Preparations><Phenotype><Process><Proteins><Publishing><Qualifying><RNA><RNA Gene Products><Research><Ribonucleic Acid><Role><Sampling><Signal Transduction><Signal Transduction Systems><Signaling><Survival Rate><Syndrome><Synovia><Synovial Fluid><Synovial Membrane><Synovium><T cell receptor repertoire sequencing><T cell receptor sequencing><T cell response><T-Cell Subsets><T-Cells><T-Lymphocyte><T-Lymphocyte Subsets><T4 Cells><T4 Lymphocytes><TCR repertoire sequencing><TCR sequencing><TCR-seq><TCRseq><TNFRSF5><TNFRSF5 gene><TSC403><Teff cell><Testing><Tissues><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><Visual><Visualization><age associated><age correlated><age dependent><age linked><age related><age specific><anti-cancer therapy><arthropathic><arthropathies><arthropathy><biological signal transduction><cancer therapy><cancer-directed therapy><cell type><check point immunotherapy><check point inhibitor therapy><check point inhibitory therapy><check point therapy><checkpoint immunotherapy><checkpoint inhibitor therapy><checkpoint inhibitory therapy><checkpoint therapy><degenerative joint disease><developmental><driving><drug/agent><effector T cell><experience><flow cytophotometry><fluid><gene panel><grasp><high dimensionality><hypertrophic arthritis><immune check point><immune check point inhibitor><immune check point therapy><immune checkpoint><immune checkpoint therapy><immune system tolerance><immune unresponsiveness><immune-mediated adverse events><immune-related adverse effect><immune-related adverse events><immune-related adverse reaction><immunecheckpoint><immunogenic><immunological paralysis><improved><inflamed joint><joint disorder><joint inflammation><joint swelling><liquid><lung cancer early detection><lung cancer screening><lymphoid structures><multigene panel><nanostring><p50><pathway><programmed cell death 1><programmed cell death protein 1><programmed death 1><response><restraint><scRNA sequencing><scRNA-seq><single cell RNA-seq><single cell RNAseq><single cell expression profiling><single cell transcriptomic profiling><single-cell RNA sequencing><sle2><social role><systemic lupus erythematosus susceptibility 2><thymus derived lymphocyte><transcriptomics><tumor>
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Robert Adam Schnoll

UNIVERSITY OF PENNSYLVANIA, PHILADELPHIA, PA

Exploratory lead · 30/100
Recent
Active award
Career award
$194,086
FY 2026

Project Title

A Mentoring Program in Patient-Oriented Tobacco Dependence and Implementation Science Research

Grant Number:

5K24DA045244-09

Activity Code:

K24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

3/1/2018

End Date:

3/31/2028

Project Abstract

Despite progress over the past 50 years in lowering the rate of smoking, tobacco use remains the leading cause of premature death in the US. To ensure the sustained and impactful research dedicated to addressing tobacco use, rigorous inter-disciplinary mentoring programs are needed to prepare the ne...

Research Terms

<AIDS Virus><AIDS care><Acquired Immune Deficiency Syndrome Virus><Acquired Immunodeficiency Syndrome Virus><Address><Appointment><Area><Award><Biological Markers><Cancer Center><Cancer Patient><Cancers><Cardiology><Cessation of life><Clinical><Communicable Diseases><Death><Dedications><Dissemination and Implementation><Drugs><EXTMR><Educational process of instructing><Educational workshop><Effectiveness><Electronic Health Record><Ensure><Evidence based treatment><Extramural><Extramural Activities><Faculty><Funding><Goals><Grant><HIV><HIV Care><HIV in patients><HIV medical care><HIV patient><HIV patient care><HIV positive patient><HIV related care><HIV related patient care><HIV-1 care><Health><Hospital Admission><Hospitalization><Human Immunodeficiency Viruses><Human immunodeficiency virus infected patients><Human immunodeficiency virus positive patients><Individual><Infectious Diseases><Infectious Disorder><Inpatients><Intention><Intermediary Metabolism><Investigators><LAV-HTLV-III><Lymphadenopathy-Associated Virus><Malignant Neoplasms><Malignant Tumor><Medication><Mentors><Mentorship><Metabolic Processes><Metabolism><Methods><N-octanoyl-beta-D-glucosylamine><N-octanoylglucosylamine><NIH><NOGA><National Institutes of Health><Neurology><Nicotine><Nicotine Dependence><Oncology><Oncology Cancer><Paper><Patients><Patients living with HIV><Patients suffering from HIV><Pennsylvania><Personalized medical approach><Pharmaceutical Preparations><Pilot Projects><Pragmatic clinical trial><Primary Care><Productivity><Publications><R-Series Research Projects><R01 Mechanism><R01 Program><Research><Research Grants><Research Personnel><Research Project Grants><Research Projects><Researchers><Salaries><Science><Scientific Publication><Scientist><Smoker><Smoking><Structure><Students><Teaching><Testing><Time><Tobacco><Tobacco Consumption><Tobacco Dependence><Tobacco smoking><Tobacco smoking behavior><Tobacco use><Training><Training Programs><Treatment Effectiveness><Underrepresented Ethnic Minority><Underrepresented Minority><United States National Institutes of Health><Universities><Virus-HIV><Wages><Washington><Work><Workshop><behavior test><behavioral economics><behavioral test><bio-markers><biologic marker><biomarker><cancer care><care delivery><care of HIV-1><career><career development><clinical care><clinical practice><conference><convention><design><designing><drug/agent><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><gene testing><gene-based testing><genetic testing><human immunodeficiency virus care><human immunodeficiency virus patient><implementation research><implementation science><implementation strategy><improved><individualized approach><malignancy><neoplasm/cancer><next generation><nicotine addiction><nicotine consumption><nicotine dependent><nicotine treatment><nicotine use><patient centered><patient infected with HIV><patient oriented><patient oriented research><patient oriented study><patient with HIV><personalization of treatment><personalized approach><personalized medicine><personalized therapy><personalized treatment><pilot study><pilot test><precision approach><premature><prematurity><programs><recruit><reduce tobacco use><reduction in tobacco use><strategies for implementation><student mentoring><student research><student-led learning><student-led research><summit><symposia><symposium><tailored approach><tobacco addiction><tobacco control><tobacco dependent><tobacco product use><tobacco use reduction><under-representation of minorities><under-represented minority><underrepresentation of minorities><varenicline><work group><working group>
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Nicole A Stadnick

SAPIEN HEALTH LLC, ARLINGTON, VA

Exploratory lead · 28/100
Above-average budget
Active award
$982,187
FY 2025

Project Title

Integration and Evaluation of the cMHQ, a Novel Transdiagnostic Mental Assessment in Clinical Pediatric Practice

Grant Number:

5R44MH127999-03

Activity Code:

R44

Mechanism:

SBIR/STTR

Agency:

NIH

Start Date:

7/16/2021

End Date:

8/31/2026

Why this may be worth a closer look

  • • Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT In this SBIR Phase II we will design, integrate, and evaluate implementation protocols in both primary care and behavioral health for the pediatric adaptation of the clinical Mental Health Quotient (cMHQ), a comprehensive transdiagnostic mental health assessment tool developed in Phase I, a...

Research Terms

<21+ years old><Address><Adolescent><Adolescent Youth><Adoption><Adult><Adult Human><Appointment><Assess implementation><Assessment instrument><Assessment tool><Child Mental Health><Childhood><Children's Hospital><Clinic><Clinical><Clinical Evaluation><Clinical Testing><Clinics and Hospitals><Clinics or Hospitals><Collaborations><Cristobalite><Development><Diagnosis><Diagnostic><Dimensions><Disease><Disorder><Effectiveness><Electronic Health Record><Emotional well being><Feedback><Feels well><Health><Health Care><Implementation assessment><Individual><Informatics><Intervention><Interview><Life><Life Style><Lifestyle><Maintenance><Maps><Medical Staff><Mental Health><Mental Health Services><Mental Hygiene><Mental Hygiene Services><Mental disorders><Mental health disorders><Methods><Monitor><Normal mental condition><Normal mental state><Normal psyche><Outcome><Patients><Pediatric Hospitals><Persons><Phase><Physicians><Position><Positioning Attribute><Preventative care><Preventive care><Primary Care><Psyche structure><Psychiatric Disease><Psychiatric Disorder><Psychological Health><Psychological Well Being><RE-AIM><Reach, Effectiveness, Adoption, Implementation, and Maintenance><Recommendation><Reporting><Research><Research Methodology><Research Methods><SBIR><Sand><Sense of well-being><Services><Silica><Silicon Dioxide><Small Business Innovation Research><Small Business Innovation Research Grant><Symptoms><Testing><Training><Trauma><Triage><Tridymite><Well in self><Work><adolescent patient><adulthood><behavioral health><child health care><clinical test><commercialization><design><designing><developmental><effectiveness and implementation trial><effectiveness/implementation hybrid trial><effectiveness/implementation trial><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><emotional wellbeing><emotional wellness><evaluate implementation><evaluation of implementation><experience><feasibility testing><flexibility><flexible><health assessment><implementation evaluation><implementation protocol><implementation research><implementation science><innovate><innovation><innovative><insight><instrument><juvenile><juvenile human><mental><mental health care><mental illness><mental well-being><mental wellbeing><mental wellness><novel><pediatric><pediatric care><pediatric health care><personalized screening><pre-clinical><precision screening><preclinical><primary care clinic><psychiatric illness><psychological disorder><psychological wellbeing><psychological wellness><reach, efficacy, adoption, implementation, and maintenance><research and methods><research clinical testing><response><self wellness><sense of wellbeing><success><tool><treatment choice>
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Tara Thiagarajan

SAPIEN HEALTH LLC, ARLINGTON, VA

Exploratory lead · 28/100
Above-average budget
Active award
$982,187
FY 2025

Project Title

Integration and Evaluation of the cMHQ, a Novel Transdiagnostic Mental Assessment in Clinical Pediatric Practice

Grant Number:

5R44MH127999-03

Activity Code:

R44

Mechanism:

SBIR/STTR

Agency:

NIH

Start Date:

7/16/2021

End Date:

8/31/2026

Why this may be worth a closer look

  • • Award size is strong enough to merit immediate review.

Project Abstract

ABSTRACT In this SBIR Phase II we will design, integrate, and evaluate implementation protocols in both primary care and behavioral health for the pediatric adaptation of the clinical Mental Health Quotient (cMHQ), a comprehensive transdiagnostic mental health assessment tool developed in Phase I, a...

Research Terms

<21+ years old><Address><Adolescent><Adolescent Youth><Adoption><Adult><Adult Human><Appointment><Assess implementation><Assessment instrument><Assessment tool><Child Mental Health><Childhood><Children's Hospital><Clinic><Clinical><Clinical Evaluation><Clinical Testing><Clinics and Hospitals><Clinics or Hospitals><Collaborations><Cristobalite><Development><Diagnosis><Diagnostic><Dimensions><Disease><Disorder><Effectiveness><Electronic Health Record><Emotional well being><Feedback><Feels well><Health><Health Care><Implementation assessment><Individual><Informatics><Intervention><Interview><Life><Life Style><Lifestyle><Maintenance><Maps><Medical Staff><Mental Health><Mental Health Services><Mental Hygiene><Mental Hygiene Services><Mental disorders><Mental health disorders><Methods><Monitor><Normal mental condition><Normal mental state><Normal psyche><Outcome><Patients><Pediatric Hospitals><Persons><Phase><Physicians><Position><Positioning Attribute><Preventative care><Preventive care><Primary Care><Psyche structure><Psychiatric Disease><Psychiatric Disorder><Psychological Health><Psychological Well Being><RE-AIM><Reach, Effectiveness, Adoption, Implementation, and Maintenance><Recommendation><Reporting><Research><Research Methodology><Research Methods><SBIR><Sand><Sense of well-being><Services><Silica><Silicon Dioxide><Small Business Innovation Research><Small Business Innovation Research Grant><Symptoms><Testing><Training><Trauma><Triage><Tridymite><Well in self><Work><adolescent patient><adulthood><behavioral health><child health care><clinical test><commercialization><design><designing><developmental><effectiveness and implementation trial><effectiveness/implementation hybrid trial><effectiveness/implementation trial><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><emotional wellbeing><emotional wellness><evaluate implementation><evaluation of implementation><experience><feasibility testing><flexibility><flexible><health assessment><implementation evaluation><implementation protocol><implementation research><implementation science><innovate><innovation><innovative><insight><instrument><juvenile><juvenile human><mental><mental health care><mental illness><mental well-being><mental wellbeing><mental wellness><novel><pediatric><pediatric care><pediatric health care><personalized screening><pre-clinical><precision screening><preclinical><primary care clinic><psychiatric illness><psychological disorder><psychological wellbeing><psychological wellness><reach, efficacy, adoption, implementation, and maintenance><research and methods><research clinical testing><response><self wellness><sense of wellbeing><success><tool><treatment choice>
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Marie-Louise Mares

UNIVERSITY OF WISCONSIN-MADISON, MADISON, WI

Exploratory lead · 28/100
Above-average budget
Active award
$762,005
FY 2025

Project Title

Using Smart Displays to Implement an Evidence-Based eHealth System for Older Adults with Multiple Chronic Conditions

Grant Number:

5R33HL151870-05

Activity Code:

R33

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/5/2021

End Date:

7/31/2026

Why this may be worth a closer look

  • • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY / ABSTRACT In addition to their debilitating impact on health and well-being, multiple chronic conditions (MCCs) account for 90% of Medicare spending. Among beneficiaries, 65% have 3 or more conditions such as diabetes and hypertension, and 23% have 5 or more. MCCs are often addresse...

Research Terms

<21+ years old><65 and older><65 or older><65 years of age and older><65 years of age or more><65 years of age or older><65+ years><65+ years old><> 65 years><AHCPR><AHRQ><Accounting><Active Follow-up><Address><Adopted><Adult><Adult Human><Age><Aged 65 and Over><Agency for Health Care Policy and Research><Agency for Healthcare Research and Quality><Anxiety><Chronic><Clinical><Communication><Competence><Control Groups><Development><Devices><Diabetes Mellitus><Elderly><Elements><Engineering><Fatigue><Funding><Geriatrics><Goals><Health><Health Care><Health Care Costs><Health Care Systems><Health Costs><Health Insurance for Aged and Disabled, Title 18><Health Insurance for Disabled Title 18><Health system><Hearing><Hyperlipemia><Hyperlipidemia><Hypertension><Intention><Internet><Intervention><Investigators><Lack of Energy><Loneliness><Marketing><Measures><Mediating><Mediator><Medical><Medicare><Mental Depression><Motivation><Obesity><Outcome><Pain><Painful><Patients><Personal Satisfaction><Phase><Physical Function><Prediabetes><Prediabetes syndrome><Prediabetic State><Primary Care><Procedures><QOL><QOL improvement><Quality of life><Randomization trial><Randomized><Reading><Research><Research Personnel><Researchers><Science><Self Determination><Self Management><Services><Sight><Sleep disturbances><Symptoms><System><Technology><Testing><Time><Title 18><Trees><Tremor><United States Agency for Health Care Policy and Research><United States Agency for Healthcare Research and Quality><Universities><Vascular Hypertensive Disease><Vascular Hypertensive Disorder><Vision><Visual><Voice><WWW><Walking><Wisconsin><aberrant sleep><above age 65><active followup><adiposity><adulthood><advanced age><after age 65><age 65 and greater><age 65 and older><age 65 or older><age > 65><age of 65 years onward><aged 65 and greater><aged 65+><aged ≥65><ages><arm><beneficiary><comparing females and males><comparing women and men><computer science><corpulence><cost><depression><developmental><diabetes><digital assistant><disrupted sleep><disturbed sleep><e-Health><eHealth><elderly patient><electronic health><electronic health system><evidence base><expectation><experience><females compared to males><females compared with males><females versus males><females vs. males><follow up><follow-up><followed up><followup><geriatric><geriatric medicine><health care management><health insurance for disabled><health management><high blood pressure><human old age (65+)><hyperpiesia><hyperpiesis><hypertensive disease><hypertensive disorder><impaired sleep><improved><improvements in QOL><improvements in quality of life><intelligent assistant><intelligent personal assistant><intervention design><intrinsic motivation><irregular sleep><laptop><literacy><lonely><multimorbidity><multiple chronic conditions><older adult><older adulthood><older patient><over 65 years><personal digital assistant><pre-diabetes><pre-diabetic><prediabetic><pressure><prevent><preventing><primary care clinic><primary outcome><programs><quality of life improvement><randomisation><randomization><randomized trial><randomized, clinical trials><randomly assigned><response><secondary outcome><senior citizen><skills><sleep disruption><sleep dysregulation><sleep/wake disruption><sleep/wake disturbance><smart speaker><smart technologies><social><success><theories><therapy design><tool><treatment design><video call><video calling><video chat><video phone call><virtual assistant><visual function><web><well-being><wellbeing><women compared to men><women compared with men><women versus men><women vs. men><world wide web><≥65 years>
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Carlos Enrique Prada

LURIE CHILDREN'S HOSPITAL OF CHICAGO, CHICAGO, IL

Exploratory lead · 28/100
Above-average budget
Active award
$734,542
FY 2025

Project Title

Developing Novel Biomarkers of Plexiform Neurofibroma Tumor Burden

Grant Number:

4R33NS122094-03

Activity Code:

R33

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

6/20/2025

End Date:

5/30/2027

Why this may be worth a closer look

  • • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT Neurofibromatosis type 1 (NF1) is a common inherited human disorder, with a frequency of approximately 1:2500 worldwide. A hallmark of NF1 is development of plexiform neurofibromas (PNFs) in 30 to 50% of NF1 patients. Currently, there are no biomarkers of tumor burden and wh...

Research Terms

<0-11 years old><Age><Animal Model><Animal Models and Related Studies><Biological Markers><Blood Plasma><Blood Serum><Cell Communication and Signaling><Cell Signaling><Child><Child Youth><Children (0-21)><Children's Hospital><Classification><Clinic><Clinical><Collection><Complex><Computer software><Country><Data><Detection><Development><Diagnosis><Diet><Disease><Disorder><Drugs><Early identification><Elephantiasis Neuromatosis><Frequencies><Glucocerebrosides><Glucosyl Ceramides><Glucosylceramides><Hereditary><History><Human><Image><Individual><Inherited><Intracellular Communication and Signaling><Laboratories><Lactosyl Ceramides><Lactosylceramides><Location><Long-term cohort><Longitudinal cohort><MEKs><MR Imaging><MR Tomography><MRI><MRIs><Magnetic Resonance Imaging><Mass Photometry/Spectrum Analysis><Mass Spectrometry><Mass Spectroscopy><Mass Spectrum><Mass Spectrum Analyses><Mass Spectrum Analysis><Measurement><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Medical center><Medication><Methods><Mice><Mice Mammals><Modeling><Modern Man><Monitor><Morbidity><Morbidity - disease rate><Murine><Mus><NMR Imaging><NMR Tomography><Nerve><Neurofibromatosis 1><Neurofibromatosis I><Neurologic Deficit><Nuclear Magnetic Resonance Imaging><Outcome><P50 Mechanism><P50 Program><Pachydermatocele><Pain><Painful><Patient risk><Patients><Pediatric Hospitals><Peripheral Nerve Sheath Neoplasm><Peripheral Nerve Sheath Tumors><Peripheral Neurofibromatosis><Pharmaceutical Preparations><Phase><Phenotype><Plasma><Plasma Serum><Plexiform Neurofibroma><Plexiform Neuromas><Population><Principal Investigator><Recklinghausen Disease of Nerve><Recklinghausen's disease><Recklinghausen's neurofibromatosis><Recording of previous events><Research Infrastructure><Reticuloendothelial System, Serum, Plasma><Risk><Running><Sampling><Serum><Signal Transduction><Signal Transduction Systems><Signaling><Software><Specialized Center><Systematics><TM-MKR><Testing><Time><Tumor Burden><Tumor Load><Tumor Markers><Tumor Royale><Tumor Volume><Type 1 Neurofibromatosis><Type I Neurofibromatosis><Validation><Visit><Work><Zeugmatography><ages><bio-markers><biobank><biologic marker><biological signal transduction><biomarker><biomarker signature><biomarker validation><biorepository><candidate biomarker><candidate identification><candidate marker><clinical infrastructure><clinical validation><cohort><depository><developmental><diets><drug/agent><histories><imaging><inhibitor><inhibitor drug><inhibitor therapeutic><inhibitor therapy><kids><marker validation><metabolism measurement><metabolomics><metabonomics><model of animal><motor disease><motor disorder><motor dysfunction><multidisciplinary><neurofibroma><new marker><non-invasive monitor><noninvasive monitor><novel><novel biomarker><novel marker><programs><recommended screening><repository><response><risk stratification><screening guidelines><screening recommendations><sex><stratify risk><tumor><tumor biomarker><tumor specific biomarker><validation studies><validations><von Recklinghausen Disease><youngster>
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Kimberly R Jordan

UNIVERSITY OF COLORADO DENVER, Aurora, CO

Exploratory lead · 28/100
Above-average budget
Active award
$584,510
FY 2025

Project Title

Development of high parameter spatial transcriptomics and proteomics for the study of tumor microenvironments

Grant Number:

1R50CA293845-01A1

Activity Code:

R50

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/12/2025

End Date:

8/31/2029

Why this may be worth a closer look

  • • Award size is strong enough to merit immediate review.

Project Abstract

Project Summary/Abstract The technical and biologic expertise offered by Research Specialists provides a foundation of support that expedites the growth of research programs, shared resources, and cancer centers. Especially important in complex fields, such as the growing use of immunotherapeutics i...

Research Terms

<Assay><Bioassay><Biological><Biological Assay><Biopsy><Body Tissues><CCSG><Cancer Center><Cancer Center Director><Cancer Center Support Grant><Cancer Patient><Cancer Treatment><Cancers><Cell Body><Cells><Children's Hospital><Clinical Research><Clinical Study><Clinical Trials><Collaborations><Colorado><Complex><Computational toolkit><Data Analyses><Data Analysis><Development><Faculty><Foundations><Funding Mechanisms><Funding Opportunities><Future><Generalized Growth><Goals><Growth><Head and Neck><Head and neck structure><Health><Human><Image><Image Analyses><Image Analysis><Imaging technology><Immune><Immune Monitoring><Immune mediated therapy><Immune response><Immunes><Immunologic Monitoring><Immunological Monitoring><Immunologically Directed Therapy><Immunology><Immunomonitoring><Immunotherapeutic agent><Immunotherapy><Individual><Investigators><Jewish><Jews><Jordan><Laboratories><Liquid substance><Malignant Neoplasm Therapy><Malignant Neoplasm Treatment><Malignant Neoplasms><Malignant Tumor><Measures><Medical><Modern Man><Patients><Pediatric Hospitals><Productivity><Proteomics><Publications><Research><Research Personnel><Research Support><Researchers><Resource Sharing><Sampling><Scientific Publication><Services><Specialist><Techniques><Technology><Time><Tissue Growth><Tissues><Training><Tumor Escape><Tumor Immune Escape><Universities><anti-cancer therapy><biologic><cancer evasion><cancer immune escape><cancer immune evasion><cancer microenvironment><cancer research center director><cancer therapy><cancer-directed therapy><combinatorial><computational toolbox><computational tools><computational toolset><computerized tools><cost><data interpretation><developmental><fluid><host response><image evaluation><image interpretation><imaging><immune drugs><immune system response><immune therapeutic approach><immune therapeutic interventions><immune therapeutic regimens><immune therapeutic strategy><immune therapy><immune-based therapeutics><immune-based therapies><immune-based treatments><immuno therapy><immunologic therapeutics><immunoresponse><immunotherapeutics><immunotherapy agent><improved><individualized cancer therapy><instrument><liquid><malignancy><member><neoplasm/cancer><new technology><novel><novel technologies><ontogeny><personalized cancer therapy><personalized cancer treatment><prognostic><programs><rational design><response><spatial RNA sequencing><spatial gene expression analysis><spatial gene expression profiling><spatial resolved transcriptome sequencing><spatial transcriptome analysis><spatial transcriptome profiling><spatial transcriptome sequencing><spatial transcriptomics><spatially resolved transcriptomics><spatio transcriptomics><stem><transcriptomics><tumor evasion><tumor immune evasion><tumor microenvironment>
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Murat Baday

REDWOOD NEURO INC., IRVINE, CA

Exploratory lead · 28/100
Above-average budget
Active award
$506,061
FY 2025

Project Title

Democratizing Early Detection and Longitudinal Monitoring of Alzheimer's Disease: An Ultra-Sensitive Blood-Based Assay

Grant Number:

1R43AG097403-01

Activity Code:

R43

Mechanism:

SBIR/STTR

Agency:

NIH

Start Date:

9/15/2025

End Date:

8/31/2026

Why this may be worth a closer look

  • • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT Redwood Neuro aims to revolutionize Alzheimer’s Disease (AD) diagnostics through the development of the SiMoLiSA platform, a pioneering technology designed to deliver a detection capability previously only achievable through high- end single molecule counting technologies. T...

Research Terms

<AD dementia><AD detection><AD diagnostic><Accuracy of Diagnosis><Address><Agreement><Alzheimer Type Dementia><Alzheimer beta-Protein><Alzheimer disease dementia><Alzheimer disease detection><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Amyloid beta-Protein><Alzheimer's Disease><Alzheimer's amyloid><Alzheimer's biomarker><Alzheimer's detection><Alzheimer's diagnosis><Alzheimer's diagnostic><Alzheimer's disease biological marker><Alzheimer's disease diagnosis><Alzheimer's disease diagnostic><Alzheimer's disease patient><Alzheimer's patient><Alzheimers Dementia><Alzheimer’s biological marker><Alzheimer’s disease biomarker><Amyloid Alzheimer's Dementia Amyloid Protein><Amyloid Beta-Peptide><Amyloid Protein A4><Amyloid beta-Protein><Amyloid β><Amyloid β-Peptide><Amyloid β-Protein><Antibodies><Assay><Aβ><Benchmarking><Best Practice Analysis><Bioassay><Biochemical Reaction><Biological Assay><Biological Markers><Blood><Blood Plasma><Blood Reticuloendothelial System><Blood Sample><Blood Serum><Blood specimen><CLIA accredited><CLIA approved><CLIA certified><CLIA compliant><CLIA licensed><Cell Communication and Signaling><Cell Signaling><Clinic><Clinical><Correlation Studies><Custom><Data><Detection><Development><Diagnostic><Digit><Digit structure><Disease Progression><ELISA><Early Diagnosis><Early Intervention><Electrodes><Enzymatic Reaction><Enzyme-Linked Immunosorbent Assay><Equipment><Event><Family><Generations><Health Care Costs><Health Care Systems><Health Costs><Human><Immunoassay><Individual><Intervention Strategies><Intracellular Communication and Signaling><Kinetics><Laboratories><Link><Liquid substance><MT-bound tau><Magnetism><Manufacturer><Measurement><Methods><Modern Man><Monitor><Nature><P50 Mechanism><P50 Program><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Performance><Phase><Plasma><Plasma Serum><Play><Primary Senile Degenerative Dementia><Printing><Process><Proteins><Public Health><QOL><Quality of life><ROC Analyses><ROC Curve><Redwood><Regression Analyses><Regression Analysis><Regression Diagnostics><Reproducibility><Research><Reticuloendothelial System, Serum, Plasma><Role><Sampling><Scheme><Sensitivity and Specificity><Serum><Signal Transduction><Signal Transduction Systems><Signaling><Specialized Center><Specificity><Statistical Correlation><Statistical Regression><System><Techniques><Technology><Testing><Transducers><Translating><Translations><Validation><Variant><Variation><a beta peptide><abeta><aged group><aged groups><aged individual><aged individuals><aged people><aged person><aged persons><aged population><aged populations><aging population><amplification and detection><amplification detection><amyloid beta><amyloid-b protein><benchmark><beta amyloid fibril><bio-markers><biologic marker><biological signal transduction><biomarker><biomarker array><biomarker panel><clinical diagnosis><clinical diagnostics><cost><cost effective><cross reactivity><customs><design><designing><detection limit><detection method><detection of amplification><detection platform><detection procedure><detection system><detection technique><developmental><diagnostic accuracy><diagnostic technologies><diagnostic tool><disease diagnostic><early detection><enzyme linked immunoassay><fluid><health goals><improved><innovate><innovation><innovative><instrumentation><liquid><magnetic><marker panel><medical diagnostic><microtubule bound tau><microtubule-bound tau><milliliter><open source><p-tau><p-τ><particle><patient living with Alzheimer's disease><patient oriented outcomes><patient suffering from Alzheimer's disease><patient with Alzheimer's><patient with Alzheimer's disease><performance tests><phospho-tau><phospho-τ><phosphorylated tau><population aging><post-translational modification of tau><posttranslational modification of tau><primary degenerative dementia><protein biomarkers><protein markers><receiver operating characteristic analyses><receiver operating characteristic curve><research facility><senile dementia of the Alzheimer type><sensor><single molecule><social role><soluble amyloid precursor protein><tau><tau Proteins><tau factor><tau phosphorylation><tau posttranslational modification><tau-1><translation><validations><τ Proteins><τ phosphorylation>
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Ahmet Ali Yanik

REDWOOD NEURO INC., IRVINE, CA

Exploratory lead · 28/100
Above-average budget
Active award
$506,061
FY 2025

Project Title

Democratizing Early Detection and Longitudinal Monitoring of Alzheimer's Disease: An Ultra-Sensitive Blood-Based Assay

Grant Number:

1R43AG097403-01

Activity Code:

R43

Mechanism:

SBIR/STTR

Agency:

NIH

Start Date:

9/15/2025

End Date:

8/31/2026

Why this may be worth a closer look

  • • Award size is strong enough to merit immediate review.

Project Abstract

PROJECT SUMMARY/ABSTRACT Redwood Neuro aims to revolutionize Alzheimer’s Disease (AD) diagnostics through the development of the SiMoLiSA platform, a pioneering technology designed to deliver a detection capability previously only achievable through high- end single molecule counting technologies. T...

Research Terms

<AD dementia><AD detection><AD diagnostic><Accuracy of Diagnosis><Address><Agreement><Alzheimer Type Dementia><Alzheimer beta-Protein><Alzheimer disease dementia><Alzheimer disease detection><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Amyloid beta-Protein><Alzheimer's Disease><Alzheimer's amyloid><Alzheimer's biomarker><Alzheimer's detection><Alzheimer's diagnosis><Alzheimer's diagnostic><Alzheimer's disease biological marker><Alzheimer's disease diagnosis><Alzheimer's disease diagnostic><Alzheimer's disease patient><Alzheimer's patient><Alzheimers Dementia><Alzheimer’s biological marker><Alzheimer’s disease biomarker><Amyloid Alzheimer's Dementia Amyloid Protein><Amyloid Beta-Peptide><Amyloid Protein A4><Amyloid beta-Protein><Amyloid β><Amyloid β-Peptide><Amyloid β-Protein><Antibodies><Assay><Aβ><Benchmarking><Best Practice Analysis><Bioassay><Biochemical Reaction><Biological Assay><Biological Markers><Blood><Blood Plasma><Blood Reticuloendothelial System><Blood Sample><Blood Serum><Blood specimen><CLIA accredited><CLIA approved><CLIA certified><CLIA compliant><CLIA licensed><Cell Communication and Signaling><Cell Signaling><Clinic><Clinical><Correlation Studies><Custom><Data><Detection><Development><Diagnostic><Digit><Digit structure><Disease Progression><ELISA><Early Diagnosis><Early Intervention><Electrodes><Enzymatic Reaction><Enzyme-Linked Immunosorbent Assay><Equipment><Event><Family><Generations><Health Care Costs><Health Care Systems><Health Costs><Human><Immunoassay><Individual><Intervention Strategies><Intracellular Communication and Signaling><Kinetics><Laboratories><Link><Liquid substance><MT-bound tau><Magnetism><Manufacturer><Measurement><Methods><Modern Man><Monitor><Nature><P50 Mechanism><P50 Program><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Performance><Phase><Plasma><Plasma Serum><Play><Primary Senile Degenerative Dementia><Printing><Process><Proteins><Public Health><QOL><Quality of life><ROC Analyses><ROC Curve><Redwood><Regression Analyses><Regression Analysis><Regression Diagnostics><Reproducibility><Research><Reticuloendothelial System, Serum, Plasma><Role><Sampling><Scheme><Sensitivity and Specificity><Serum><Signal Transduction><Signal Transduction Systems><Signaling><Specialized Center><Specificity><Statistical Correlation><Statistical Regression><System><Techniques><Technology><Testing><Transducers><Translating><Translations><Validation><Variant><Variation><a beta peptide><abeta><aged group><aged groups><aged individual><aged individuals><aged people><aged person><aged persons><aged population><aged populations><aging population><amplification and detection><amplification detection><amyloid beta><amyloid-b protein><benchmark><beta amyloid fibril><bio-markers><biologic marker><biological signal transduction><biomarker><biomarker array><biomarker panel><clinical diagnosis><clinical diagnostics><cost><cost effective><cross reactivity><customs><design><designing><detection limit><detection method><detection of amplification><detection platform><detection procedure><detection system><detection technique><developmental><diagnostic accuracy><diagnostic technologies><diagnostic tool><disease diagnostic><early detection><enzyme linked immunoassay><fluid><health goals><improved><innovate><innovation><innovative><instrumentation><liquid><magnetic><marker panel><medical diagnostic><microtubule bound tau><microtubule-bound tau><milliliter><open source><p-tau><p-τ><particle><patient living with Alzheimer's disease><patient oriented outcomes><patient suffering from Alzheimer's disease><patient with Alzheimer's><patient with Alzheimer's disease><performance tests><phospho-tau><phospho-τ><phosphorylated tau><population aging><post-translational modification of tau><posttranslational modification of tau><primary degenerative dementia><protein biomarkers><protein markers><receiver operating characteristic analyses><receiver operating characteristic curve><research facility><senile dementia of the Alzheimer type><sensor><single molecule><social role><soluble amyloid precursor protein><tau><tau Proteins><tau factor><tau phosphorylation><tau posttranslational modification><tau-1><translation><validations><τ Proteins><τ phosphorylation>
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Kyle Ellrott

OREGON HEALTH & SCIENCE UNIVERSITY, PORTLAND, OR

Exploratory lead · 28/100
Solid budget
Active award
Team-scale grant
$369,600
FY 2025

Project Title

OHSU Center for Specialized Data Analysis as part of the GDAN

Grant Number:

5U24CA264007-05

Activity Code:

U24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

9/1/2021

End Date:

8/31/2026

Project Abstract

Project Summary Recent advances in therapeutics have improved survival rates for many cancers. However, nearly all metastatic tumors are incurable, and resistance to therapeutic interventions is nearly universal. There are many reasons for our lack of progress-foremost of which is lack of understand...

Research Terms

<Acceleration><Address><Algorithms><Area><Bioinformatics><Biological><Cancer Biology><Cancer Center><Cancers><Charge><Clinical><Clinical Trials><Clinical Trials Design><Communities><Competence><Computational toolkit><Computer software><DNA mutation><Data><Data Analyses><Data Analysis><Data Set><Detection><Development><Disease><Disorder><Distributed Systems><Dreams><Drug Therapy><Ensure><Evolution><Future><Genetic Change><Genetic Heterogeneity><Genetic defect><Genetic mutation><Genomic approach><Genomics><Goals><Heterogeneity><Individual><Infrastructure><Investigators><Knowledge><Learning><Malignant Neoplasms><Malignant Tumor><Malignant neoplasm of prostate><Malignant prostatic tumor><Manuals><Messenger RNA><Metastasis><Metastasize><Metastatic Lesion><Metastatic Mass><Metastatic Neoplasm><Metastatic Tumor><Methodology><Methods><Mutation><Neoplasm Metastasis><Network Analysis><P50 Mechanism><P50 Program><Pathway Analysis><Pathway interactions><Patients><Pharmacological Treatment><Pharmacotherapy><Preventative strategy><Prevention strategy><Preventive strategy><Process><Prognostic Marker><Prostate CA><Prostate Cancer><Prostate malignancy><Quality Control><RNA Seq><RNA sequencing><RNAseq><Research><Research Personnel><Researchers><Resistance><Running><Sampling><Secondary Neoplasm><Secondary Tumor><Services><Site><Software><Specialized Center><Survival Rate><System><Systems Integration><TCGA><The Cancer Genome Atlas><Therapeutic><Therapeutic Intervention><Training><Update><Visualization><Work><bio-informatics tool><bioinformatics tool><biologic><cancer genomics><cancer initiation><cancer metastasis><cancer prevention><cell free DNA><cell free circulating DNA><clinical care><cluster computing><complex data><computational infrastructure><computational toolbox><computational tools><computational toolset><computer infrastructure><computerized tools><data analysis pipeline><data grid><data integration><data interpretation><data processing pipeline><datagrid><developmental><diagnostic biomarker><diagnostic marker><distributed computing><drug intervention><drug treatment><experience><genetic evolution><genome mutation><genomic data><genomic dataset><genomic effort><genomic strategy><improved><innovate><innovation><innovative><integrated system><intervention therapy><mRNA><malignancy><multidisciplinary><neoplasm/cancer><new approaches><new diagnostics><next generation diagnostics><novel><novel approaches><novel diagnostics><novel strategies><novel strategy><oncogenomics><pathway><patient subclass><patient subcluster><patient subgroups><patient subpopulations><patient subsets><patient subtypes><pharmaceutical intervention><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><precision medicine><precision-based medicine><prognostic biomarker><prognostic indicator><programs><resistance to therapy><resistant><resistant to therapy><response><scRNA sequencing><scRNA-seq><single cell RNA-seq><single cell RNAseq><single cell expression profiling><single cell transcriptomic profiling><single-cell RNA sequencing><structural mutation><structural variant><structural variation><success><system integration><therapeutic resistance><therapy resistant><transcriptome sequencing><transcriptomic sequencing><treatment resistance><treatment strategy><tumor><tumor DNA><tumor cell DNA><tumor cell metastasis><tumor-specific DNA><work group><working group>
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PAUL T. SPELLMAN

OREGON HEALTH & SCIENCE UNIVERSITY, PORTLAND, OR

Exploratory lead · 28/100
Solid budget
Active award
Team-scale grant
$369,600
FY 2025

Project Title

OHSU Center for Specialized Data Analysis as part of the GDAN

Grant Number:

5U24CA264007-05

Activity Code:

U24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

9/1/2021

End Date:

8/31/2026

Project Abstract

Project Summary Recent advances in therapeutics have improved survival rates for many cancers. However, nearly all metastatic tumors are incurable, and resistance to therapeutic interventions is nearly universal. There are many reasons for our lack of progress-foremost of which is lack of understand...

Research Terms

<Acceleration><Address><Algorithms><Area><Bioinformatics><Biological><Cancer Biology><Cancer Center><Cancers><Charge><Clinical><Clinical Trials><Clinical Trials Design><Communities><Competence><Computational toolkit><Computer software><DNA mutation><Data><Data Analyses><Data Analysis><Data Set><Detection><Development><Disease><Disorder><Distributed Systems><Dreams><Drug Therapy><Ensure><Evolution><Future><Genetic Change><Genetic Heterogeneity><Genetic defect><Genetic mutation><Genomic approach><Genomics><Goals><Heterogeneity><Individual><Infrastructure><Investigators><Knowledge><Learning><Malignant Neoplasms><Malignant Tumor><Malignant neoplasm of prostate><Malignant prostatic tumor><Manuals><Messenger RNA><Metastasis><Metastasize><Metastatic Lesion><Metastatic Mass><Metastatic Neoplasm><Metastatic Tumor><Methodology><Methods><Mutation><Neoplasm Metastasis><Network Analysis><P50 Mechanism><P50 Program><Pathway Analysis><Pathway interactions><Patients><Pharmacological Treatment><Pharmacotherapy><Preventative strategy><Prevention strategy><Preventive strategy><Process><Prognostic Marker><Prostate CA><Prostate Cancer><Prostate malignancy><Quality Control><RNA Seq><RNA sequencing><RNAseq><Research><Research Personnel><Researchers><Resistance><Running><Sampling><Secondary Neoplasm><Secondary Tumor><Services><Site><Software><Specialized Center><Survival Rate><System><Systems Integration><TCGA><The Cancer Genome Atlas><Therapeutic><Therapeutic Intervention><Training><Update><Visualization><Work><bio-informatics tool><bioinformatics tool><biologic><cancer genomics><cancer initiation><cancer metastasis><cancer prevention><cell free DNA><cell free circulating DNA><clinical care><cluster computing><complex data><computational infrastructure><computational toolbox><computational tools><computational toolset><computer infrastructure><computerized tools><data analysis pipeline><data grid><data integration><data interpretation><data processing pipeline><datagrid><developmental><diagnostic biomarker><diagnostic marker><distributed computing><drug intervention><drug treatment><experience><genetic evolution><genome mutation><genomic data><genomic dataset><genomic effort><genomic strategy><improved><innovate><innovation><innovative><integrated system><intervention therapy><mRNA><malignancy><multidisciplinary><neoplasm/cancer><new approaches><new diagnostics><next generation diagnostics><novel><novel approaches><novel diagnostics><novel strategies><novel strategy><oncogenomics><pathway><patient subclass><patient subcluster><patient subgroups><patient subpopulations><patient subsets><patient subtypes><pharmaceutical intervention><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><precision medicine><precision-based medicine><prognostic biomarker><prognostic indicator><programs><resistance to therapy><resistant><resistant to therapy><response><scRNA sequencing><scRNA-seq><single cell RNA-seq><single cell RNAseq><single cell expression profiling><single cell transcriptomic profiling><single-cell RNA sequencing><structural mutation><structural variant><structural variation><success><system integration><therapeutic resistance><therapy resistant><transcriptome sequencing><transcriptomic sequencing><treatment resistance><treatment strategy><tumor><tumor DNA><tumor cell DNA><tumor cell metastasis><tumor-specific DNA><work group><working group>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Mark Joseph Gage

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

Exploratory lead · 28/100
Solid budget
Active award
Team-scale grant
$267,527
FY 2025

Project Title

Accelerated Flap Coverage Versus Standard Timing in the Treatment of Severe Lower Extremity Musculoskeletal Injuries

Grant Number:

1UG3AR085896-01

Activity Code:

UG3

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/10/2025

End Date:

8/31/2026

Project Abstract

In the United States (US), there are more than 300,000 lower extremity musculoskeletal injuries each year. In patients with severe injuries, 20-40% will develop an infection. Patients at highest risk for infection have open injuries where the bone breaks through the skin causing skin and muscle dama...

Research Terms

<Acceleration><Address><Amputation><Antibiotic Agents><Antibiotic Drugs><Antibiotics><Area><Body Tissues><Bone Injury><Caring><Client satisfaction><Clinical><Clinical Trials><Complication><Compound Fractures><Data><Debridement><Dislocations><Drops><Environment><Foundations><Fracture><Funding><Global Change><Guidelines><Hospitals><Hour><Individual><Infection><Infection prevention><Infrastructure><Injury><Institution><International><Island Flaps><Knee><Knowledge><Lower Extremity><Lower Limb><Measures><Membrum inferius><Miscellaneous Antibiotic><Muscle><Muscle Tissue><Open Fractures><Operating Rooms><Operative Procedures><Operative Surgical Procedures><Orthopedic><Orthopedic Surgical Profession><Orthopedics><Outcome><P50 Mechanism><P50 Program><Participant><Pathway interactions><Patient Satisfaction><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Pattern><Plastic Surgeon><Prevent infection><Prevention><Prevention Research><QOL><QOL improvement><Quality of life><Randomized><Randomized, Controlled Trials><Reoperation><Repeat Surgery><Research Resources><Resources><Retrospective Studies><Risk Reduction><Severities><Site><Skin><Specialized Center><Surgeon><Surgical><Surgical Flaps><Surgical Interventions><Surgical Procedure><Testing><Time><Tissues><Trauma><United Kingdom><United States><Vascularization><Work><bone fracture><critical injury><cutaneous damage><dermal damage><devastating injury><epidermal damage><extremity injury><extremity trauma><high risk><improved><improvements in QOL><improvements in quality of life><infection rate><infection risk><injuries><injury of musculoskeletal system (disorder)><injury of musculoskeleted system><injury to extremity><limb injury><limb trauma><mortality><muscular><musculoskeletal injury><musculoskeletal trauma><open wound><pathway><patient oriented outcomes><primary outcome><quality of life improvement><randomisation><randomization><randomized control trial><randomly assigned><rate of infection><reconstruction><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><risk-reducing><severe injury><skin damage><soft tissue><standard of care><success><surgery><tissue reconstruction><trauma care><trial comparing><trial planning>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Lily Mundy

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

Exploratory lead · 28/100
Solid budget
Active award
Team-scale grant
$267,527
FY 2025

Project Title

Accelerated Flap Coverage Versus Standard Timing in the Treatment of Severe Lower Extremity Musculoskeletal Injuries

Grant Number:

1UG3AR085896-01

Activity Code:

UG3

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/10/2025

End Date:

8/31/2026

Project Abstract

In the United States (US), there are more than 300,000 lower extremity musculoskeletal injuries each year. In patients with severe injuries, 20-40% will develop an infection. Patients at highest risk for infection have open injuries where the bone breaks through the skin causing skin and muscle dama...

Research Terms

<Acceleration><Address><Amputation><Antibiotic Agents><Antibiotic Drugs><Antibiotics><Area><Body Tissues><Bone Injury><Caring><Client satisfaction><Clinical><Clinical Trials><Complication><Compound Fractures><Data><Debridement><Dislocations><Drops><Environment><Foundations><Fracture><Funding><Global Change><Guidelines><Hospitals><Hour><Individual><Infection><Infection prevention><Infrastructure><Injury><Institution><International><Island Flaps><Knee><Knowledge><Lower Extremity><Lower Limb><Measures><Membrum inferius><Miscellaneous Antibiotic><Muscle><Muscle Tissue><Open Fractures><Operating Rooms><Operative Procedures><Operative Surgical Procedures><Orthopedic><Orthopedic Surgical Profession><Orthopedics><Outcome><P50 Mechanism><P50 Program><Participant><Pathway interactions><Patient Satisfaction><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Pattern><Plastic Surgeon><Prevent infection><Prevention><Prevention Research><QOL><QOL improvement><Quality of life><Randomized><Randomized, Controlled Trials><Reoperation><Repeat Surgery><Research Resources><Resources><Retrospective Studies><Risk Reduction><Severities><Site><Skin><Specialized Center><Surgeon><Surgical><Surgical Flaps><Surgical Interventions><Surgical Procedure><Testing><Time><Tissues><Trauma><United Kingdom><United States><Vascularization><Work><bone fracture><critical injury><cutaneous damage><dermal damage><devastating injury><epidermal damage><extremity injury><extremity trauma><high risk><improved><improvements in QOL><improvements in quality of life><infection rate><infection risk><injuries><injury of musculoskeletal system (disorder)><injury of musculoskeleted system><injury to extremity><limb injury><limb trauma><mortality><muscular><musculoskeletal injury><musculoskeletal trauma><open wound><pathway><patient oriented outcomes><primary outcome><quality of life improvement><randomisation><randomization><randomized control trial><randomly assigned><rate of infection><reconstruction><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><risk-reducing><severe injury><skin damage><soft tissue><standard of care><success><surgery><tissue reconstruction><trauma care><trial comparing><trial planning>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Sheila Sprague

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

Exploratory lead · 28/100
Solid budget
Active award
Team-scale grant
$267,527
FY 2025

Project Title

Accelerated Flap Coverage Versus Standard Timing in the Treatment of Severe Lower Extremity Musculoskeletal Injuries

Grant Number:

1UG3AR085896-01

Activity Code:

UG3

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/10/2025

End Date:

8/31/2026

Project Abstract

In the United States (US), there are more than 300,000 lower extremity musculoskeletal injuries each year. In patients with severe injuries, 20-40% will develop an infection. Patients at highest risk for infection have open injuries where the bone breaks through the skin causing skin and muscle dama...

Research Terms

<Acceleration><Address><Amputation><Antibiotic Agents><Antibiotic Drugs><Antibiotics><Area><Body Tissues><Bone Injury><Caring><Client satisfaction><Clinical><Clinical Trials><Complication><Compound Fractures><Data><Debridement><Dislocations><Drops><Environment><Foundations><Fracture><Funding><Global Change><Guidelines><Hospitals><Hour><Individual><Infection><Infection prevention><Infrastructure><Injury><Institution><International><Island Flaps><Knee><Knowledge><Lower Extremity><Lower Limb><Measures><Membrum inferius><Miscellaneous Antibiotic><Muscle><Muscle Tissue><Open Fractures><Operating Rooms><Operative Procedures><Operative Surgical Procedures><Orthopedic><Orthopedic Surgical Profession><Orthopedics><Outcome><P50 Mechanism><P50 Program><Participant><Pathway interactions><Patient Satisfaction><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Pattern><Plastic Surgeon><Prevent infection><Prevention><Prevention Research><QOL><QOL improvement><Quality of life><Randomized><Randomized, Controlled Trials><Reoperation><Repeat Surgery><Research Resources><Resources><Retrospective Studies><Risk Reduction><Severities><Site><Skin><Specialized Center><Surgeon><Surgical><Surgical Flaps><Surgical Interventions><Surgical Procedure><Testing><Time><Tissues><Trauma><United Kingdom><United States><Vascularization><Work><bone fracture><critical injury><cutaneous damage><dermal damage><devastating injury><epidermal damage><extremity injury><extremity trauma><high risk><improved><improvements in QOL><improvements in quality of life><infection rate><infection risk><injuries><injury of musculoskeletal system (disorder)><injury of musculoskeleted system><injury to extremity><limb injury><limb trauma><mortality><muscular><musculoskeletal injury><musculoskeletal trauma><open wound><pathway><patient oriented outcomes><primary outcome><quality of life improvement><randomisation><randomization><randomized control trial><randomly assigned><rate of infection><reconstruction><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><risk-reducing><severe injury><skin damage><soft tissue><standard of care><success><surgery><tissue reconstruction><trauma care><trial comparing><trial planning>
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William T. Carpenter

UNIVERSITY OF MARYLAND BALTIMORE, BALTIMORE, MD

Exploratory lead · 28/100
Training-friendly
Active award
$216,097
FY 2025

Project Title

Multidisciplinary Schizophrenia Research Training

Grant Number:

5T32MH067533-20

Activity Code:

T32

Mechanism:

Training, Institutional

Agency:

NIH

Start Date:

7/1/2004

End Date:

6/30/2026

Why this may be worth a closer look

  • • Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

Project Summary This is the third competitive renewal of a T32 training grant at the Maryland Psychiatric Research Center (MPRC), originally funded in 2003 (MH067533). The goal of the proposed program is to prepare MDs, PhDs and PharmDs interested in basic or clinical research for a career in transl...

Research Terms

<Research Training><Schizophrenia><Schizophrenic Disorders><dementia praecox><multidisciplinary><schizophrenic>
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Gregory I Elmer

UNIVERSITY OF MARYLAND BALTIMORE, BALTIMORE, MD

Exploratory lead · 28/100
Training-friendly
Active award
$216,097
FY 2025

Project Title

Multidisciplinary Schizophrenia Research Training

Grant Number:

5T32MH067533-20

Activity Code:

T32

Mechanism:

Training, Institutional

Agency:

NIH

Start Date:

7/1/2004

End Date:

6/30/2026

Why this may be worth a closer look

  • • Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

Project Summary This is the third competitive renewal of a T32 training grant at the Maryland Psychiatric Research Center (MPRC), originally funded in 2003 (MH067533). The goal of the proposed program is to prepare MDs, PhDs and PharmDs interested in basic or clinical research for a career in transl...

Research Terms

<Research Training><Schizophrenia><Schizophrenic Disorders><dementia praecox><multidisciplinary><schizophrenic>
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DEANNA L KELLY

UNIVERSITY OF MARYLAND BALTIMORE, BALTIMORE, MD

Exploratory lead · 28/100
Training-friendly
Active award
$216,097
FY 2025

Project Title

Multidisciplinary Schizophrenia Research Training

Grant Number:

5T32MH067533-20

Activity Code:

T32

Mechanism:

Training, Institutional

Agency:

NIH

Start Date:

7/1/2004

End Date:

6/30/2026

Why this may be worth a closer look

  • • Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

Project Summary This is the third competitive renewal of a T32 training grant at the Maryland Psychiatric Research Center (MPRC), originally funded in 2003 (MH067533). The goal of the proposed program is to prepare MDs, PhDs and PharmDs interested in basic or clinical research for a career in transl...

Research Terms

<Research Training><Schizophrenia><Schizophrenic Disorders><dementia praecox><multidisciplinary><schizophrenic>
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Jonathan L Brigman

UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR, ALBUQUERQUE, NM

Exploratory lead · 28/100
Training-friendly
Active award
$184,208
FY 2025

Project Title

Alcohol Research Training in Neurosciences

Grant Number:

5T32AA014127-23

Activity Code:

T32

Mechanism:

Training, Institutional

Agency:

NIH

Start Date:

8/8/2003

End Date:

7/31/2028

Why this may be worth a closer look

  • • Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

The Alcohol Training Program in Neurosciences at the University of New Mexico (UNM-ARTN) has increased visibility of alcohol research across campus. Since 2003, the UNM-ARTN grant has supported 34 trainees, 12 in the past 5 years. Since 2006, we have filled all our training slots and trainees have b...

Research Terms

<Neurosciences><Research Training><alcohol related research><alcohol research><ethanol research>
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Emily Haroz

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

Exploratory lead · 28/100
Training-friendly
Active award
$162,903
FY 2025

Project Title

Elevating Indigenous Wellbeing through Assets-Based Prevention Science (ELEVATE) Training Program

Grant Number:

5T32DA061087-02

Activity Code:

T32

Mechanism:

Training, Institutional

Agency:

NIH

Start Date:

7/1/2024

End Date:

6/30/2029

Why this may be worth a closer look

  • • Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

ABSTRACT Indigenous peoples in the United States and worldwide face the starkest inequities in premature mortality of any racial and ethnic group. In the United States, American Indian/ Alaska Native (AI/AN) Peoples have 2X higher rates of suicide, 4X higher rates of alcohol induced deaths, and 1.6X...

Research Terms

<Indigenous><Personal Satisfaction><Prevention><Science><Training Programs><well-being><wellbeing>
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Melissa L. Walls

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

Exploratory lead · 28/100
Training-friendly
Active award
$162,903
FY 2025

Project Title

Elevating Indigenous Wellbeing through Assets-Based Prevention Science (ELEVATE) Training Program

Grant Number:

5T32DA061087-02

Activity Code:

T32

Mechanism:

Training, Institutional

Agency:

NIH

Start Date:

7/1/2024

End Date:

6/30/2029

Why this may be worth a closer look

  • • Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

ABSTRACT Indigenous peoples in the United States and worldwide face the starkest inequities in premature mortality of any racial and ethnic group. In the United States, American Indian/ Alaska Native (AI/AN) Peoples have 2X higher rates of suicide, 4X higher rates of alcohol induced deaths, and 1.6X...

Research Terms

<Indigenous><Personal Satisfaction><Prevention><Science><Training Programs><well-being><wellbeing>
View Full Project Details on NIH Reporter
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Lealah Pollock

UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, SAN FRANCISCO, CA

Exploratory lead · 28/100
Training-friendly
Active award
$162,000
FY 2025

Project Title

Enhancing Primary Care Residency Training in Specialized and Individualized Patient Care

Grant Number:

5R25LM014550-02

Activity Code:

R25

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

7/26/2024

End Date:

5/31/2028

Why this may be worth a closer look

  • • Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

The project will now focus on developing and implementing a comprehensive curriculum for Family Medicine residents centered on managing complex clinical needs in a patient-centered and individualized manner. The revised curriculum removes identity-based framing and instead emphasizes clinical prepar...

Research Terms

<Area><Caring><Chronic Disease><Chronic Illness><Clinic><Clinical><Competence><Complex><Curriculum><Disease Management><Disorder Management><Educational Curriculum><Effectiveness><Exposure to><Family Practice><Feedback><Health Care><Learning><Medical><Outcome><P50 Mechanism><P50 Program><Patient Care><Patient Care Delivery><Patients><Precision care><Preparedness><Preventative care><Preventive care><Primary Care><Readiness><Residencies><Rotation><Site><Specialized Center><Structure><Survey Instrument><Surveys><Training><care delivery><care for patients><care of patients><caring for patients><chronic disorder><clinical training><community clinic><community partners><community-based partners><design><designing><didactic curriculum><didactic education><experience><family medicine><improved><individualized care><individualized patient care><lesson plans><meeting><meetings><patient centered><patient oriented><personalized care><personalized patient care><programs><skills>
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David W Clapp

INDIANA UNIVERSITY INDIANAPOLIS, INDIANAPOLIS, IN

Exploratory lead · 28/100
Training-friendly
Active award
$141,457
FY 2025

Project Title

Pediatric and Adult Translational Cancer Drug Discovery and Development Training Program (PACT-D3)

Grant Number:

5T32CA272370-03

Activity Code:

T32

Mechanism:

Training, Institutional

Agency:

NIH

Start Date:

9/1/2023

End Date:

8/31/2028

Why this may be worth a closer look

  • • Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

Abstract This training program is unique for our institution, creating the next generation of basic and clinical investigators who focus their efforts on strategic and comprehensive drug discovery and development in cancer. This program capitalizes on a strong infrastructure and institutional commit...

Research Terms

<21+ years old><Adult><Adult Human><Anti-Cancer Agents><Antineoplastic Agents><Antineoplastic Drugs><Antineoplastics><Cancer Drug><Childhood><Neoplastic Disease Chemotherapeutic Agents><Training Programs><Tumor-Specific Treatment Agents><adulthood><anti-cancer drug><drug development><drug discovery><pediatric>
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Mark R. Kelley

INDIANA UNIVERSITY INDIANAPOLIS, INDIANAPOLIS, IN

Exploratory lead · 28/100
Training-friendly
Active award
$141,457
FY 2025

Project Title

Pediatric and Adult Translational Cancer Drug Discovery and Development Training Program (PACT-D3)

Grant Number:

5T32CA272370-03

Activity Code:

T32

Mechanism:

Training, Institutional

Agency:

NIH

Start Date:

9/1/2023

End Date:

8/31/2028

Why this may be worth a closer look

  • • Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

Abstract This training program is unique for our institution, creating the next generation of basic and clinical investigators who focus their efforts on strategic and comprehensive drug discovery and development in cancer. This program capitalizes on a strong infrastructure and institutional commit...

Research Terms

<21+ years old><Adult><Adult Human><Anti-Cancer Agents><Antineoplastic Agents><Antineoplastic Drugs><Antineoplastics><Cancer Drug><Childhood><Neoplastic Disease Chemotherapeutic Agents><Training Programs><Tumor-Specific Treatment Agents><adulthood><anti-cancer drug><drug development><drug discovery><pediatric>
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EDWARD CANTU

UNIVERSITY OF PENNSYLVANIA, PHILADELPHIA, PA

Exploratory lead · 26/100
Likely hiring
$223,515
FY 2025

Project Title

Objective lung assessment tools for improved organ use in lung transplantation

Grant Number:

5R01HL155821-05

Activity Code:

R01

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

7/15/2021

End Date:

8/31/2025

Why this may be worth a closer look

  • • Mechanism often supports lab expansion or staff hiring.

Project Abstract

Project Summary/Abstract Primary graft dysfunction (PGD) is the most common cause of morbidity and mortality after lung transplantation resulting in significant negative effects on quality of life and cost. PGD has a complex relationship with donor organ use because uncertainty in organ quality and ...

Research Terms

<Acute><Acute Lung Injury><Acute Pulmonary Injury><Address><Affect><American><Assessment instrument><Assessment tool><Blood><Blood Reticuloendothelial System><Body Temperature><Cause of Death><Cessation of life><Chronic lung disease><Clinical><Cohort Studies><Collaborations><Complex><Concurrent Studies><Death><Decision Making><Disease><Disorder><Donor Screening><Donor Selection><Donor person><Early identification><Fear><Fright><Funding><Future><Gene Expression><Grafting Procedure><Hour><Hypoxia><Hypoxic><Immune Cell Activation><Infiltration><Infrastructure><Knowledge><Life><Lung><Lung Grafting><Lung Parenchyma><Lung Respiratory System><Lung Tissue><Lung Transplantation><Lung damage><Measures><Methods><Morbidity><Morbidity - disease rate><Multi-center studies><Multicenter Studies><NIH><National Institutes of Health><Organ><Organ Donor><Organ Procurements><Organ Transplantation><Organ Transplants><Organ failure><Outcome><Oxygen Deficiency><P50 Mechanism><P50 Program><Pathogenesis><Pathway interactions><Patients><Perfusion><Perioperative><Population><Position><Positioning Attribute><Postoperative><Postoperative Period><Predisposition><Preparation><Preventive><Probability><Prospective cohort><Public Health><Pulmonary Graft><Pulmonary Transplant><Pulmonary Transplantation><QOL><Quality of life><Radiography><Reproducibility><Research><Risk><Risk Assessment><Roentgenography><Selection Criteria><Signal Pathway><Specialized Center><Structure of parenchyma of lung><Susceptibility><Syndrome><TLR protein><Technology><Therapeutic><Toll-Like Receptor Family Gene><Toll-Like Receptor Pathway><Toll-like receptors><Transcript><Transplant Recipients><Transplantation><Uncertainty><United States National Institutes of Health><Update><Waiting Lists><Work><biomarker identification><candidate selection><chronic pulmonary disease><clinical predictors><clinical trial enrollment><cost><doubt><graft dysfunction><high risk><identification of biomarkers><identification of new biomarkers><immune activation><implantation><improved><innate immune pathways><lung injury><lung transplant><marker identification><mortality><new technology><novel><novel technologies><oncology trial><organ allograft><organ graft><organ xenograft><pathway><predictive tools><preparations><prevent><preventing><prospective><pulmonary damage><pulmonary injury><pulmonary tissue damage><pulmonary tissue injury><radiological imaging><risk stratification><stratify risk><tool><transplant><transplant centers><transplant donor><transplant patient><ventilation><waitlist>
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Jagan Muppidi

DIVISION OF BASIC SCIENCES - NCI

Exploratory lead · 24/100
Large award
$1,966,842
FY 2025

Project Title

The role of Galpha13 signaling in suppression of lymphoma

Grant Number:

1ZIABC011772-09

Activity Code:

ZIA

Mechanism:

Intramural Research

Agency:

NIH

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.

Project Abstract

Aim 1- Mechanism of Galpha13-mediated tumor suppression in mucosal germinal center B cells. B cells in GCs are among the most highly proliferative somatic cells in the body and are strictly confined to the GC niche that forms at the center of the B cell follicle. In previous work, we defined a tumor...

Research Terms

<AICDA><AICDA protein><AID gene><AID protein><Acute B-Lymphocytic Leukemia><Age><Alleles><Allelomorphs><Anatomic Sites><Anatomic structures><Anatomy><Antibodies><Antibody Affinity><B blood cells><B cell><B cell differentiation><B cell lymphoma 6><B cell progenitor acute lymphoblastic leukemia><B cells><B lymphocyte differentiation><B-ALL><B-Cell Acute Lymphocytic Leukemia><B-Cell Activation><B-Cell Acute Lymphoblastic Leukemia><B-Cell CLL/Lymphoma-6 Gene><B-Cell Lymphoblastic Leukemia><B-Cells><B-Lymphocytes><B-cell><B-cell ALL><B-cell precursor acute lymphoblastic leukemia><BCL5><BCL6><BCL6 gene><Biology><Blood><Blood Plasma Cell><Blood Reticuloendothelial System><CDA2 protein><CRISPR approach><CRISPR based approach><CRISPR method><CRISPR methodology><CRISPR technique><CRISPR technology><CRISPR tools><CRISPR-CAS-9><CRISPR-based method><CRISPR-based technique><CRISPR-based technology><CRISPR-based tool><CRISPR/CAS approach><CRISPR/Cas method><CRISPR/Cas technology><CRISPR/Cas9><CRISPR/Cas9 technology><Cancers><Cas nuclease technology><Categories><Cell Body><Cell Communication and Signaling><Cell Count><Cell Number><Cell Signaling><Cells><Chronic><Classification Scheme><Clinical><Clustered Regularly Interspaced Short Palindromic Repeats approach><Clustered Regularly Interspaced Short Palindromic Repeats method><Clustered Regularly Interspaced Short Palindromic Repeats methodology><Clustered Regularly Interspaced Short Palindromic Repeats technique><Clustered Regularly Interspaced Short Palindromic Repeats technology><Cues><Cys-His2 Zinc Finger Transcription Factor Gene><DLBCL><DNA Alteration><DNA Sequence Alteration><DNA mutation><Dependence><Development><Diet><Diffuse Large B-Cell Lymphoma><Disease><Disorder><Enzyme Activation><Event><Future><G-Proteins><GEM model><GEMM model><GI microbiota><GTP-Binding Proteins><GTP-Regulatory Proteins><Gastrointestinal microbiota><Gene Expression><Gene Expression Monitoring><Gene Expression Pattern Analysis><Gene Expression Profiling><Gene with Unknown or Unclassified Function><Genes><Genetic><Genetic Alteration><Genetic Change><Genetic Heterogeneity><Genetic defect><Genetic mutation><Genetically Engineered Mouse><Germinal Center><Germinoblastic Sarcoma><Germinoblastoma><Gln><Glutamine><Goals><Guanine Nucleotide Coupling Protein><Guanine Nucleotide Regulatory Proteins><Heterogeneity><Human><Humoral Immunities><Ig Somatic Hypermutation><Immune response><Immunization><Immunize><Immuno-Chemotherapy><Immunochemotherapy><Immunoglobulin Somatic Hypermutation><Immunology><In Vitro><Individual><Infection><Intracellular Communication and Signaling><L-Glutamine><LAZ-3 Gene><LAZ3><Lesion><Lymph><Lymphatic><Lymphoma><Lymphomagenesis><MYC Family Protein><MYC Protein><Malignant Lymphoma><Malignant Neoplasms><Malignant Tumor><Mediating><Memory B Cell><Memory B-Lymphocyte><Mice><Mice Mammals><Modern Man><Modification><Molecular><Molecular Tumor Suppression><Mucosa><Mucosal Tissue><Mucous Membrane><Murine><Mus><Mutation><Nature><Nutrient><Oncogenesis><Outcome><P50 Mechanism><P50 Program><Pathogenesis><Pathogenicity><Pathway interactions><Peyer's Patches><Plasma Cells><Plasmacytes><Pre-B-Cell Leukemia><Precancerous Cells><Precursor B Lymphoblastic Leukemia><Premalignant Cell><Process><Prognosis><Proliferating><Q Levoglutamide><Q. Levoglutamide><Reaction><Recurrence><Recurrent><Research><Reticulolymphosarcoma><Role><Sequence Alteration><Signal Transduction><Signal Transduction Systems><Signaling><Site><Somatic Cell><Specialized Center><Spleen><Spleen Reticuloendothelial System><Stimulus><Structure><Structure of germinal center of lymph node><T-Cells><T-Lymphocyte><Transcript Expression Analyses><Transcript Expression Analysis><Tropism><Tumor Suppression><Unclassified Gene><Work><ZNF51><ZNF51 Gene><Zinc Finger Protein 51 Gene><activated B cells><activation-induced cytidine deaminase><activation-induced deaminase><aged animal><aged animals><ages><analyze gene expression><animal old age><antibody-based immunity><antigen antibody affinity><biological signal transduction><cell behavior><cellular behavior><chemo-immuno therapy><chemoimmunotherapy><clinical heterogeneity><developmental><dietary><diets><elderly animal><enteric microbial community><enteric microbiota><gain of function mutation><gastrointestinal microbial flora><gene expression analysis><gene expression assay><genetically engineered mouse model><genetically engineered murine model><genome mutation><genomic alteration><gut community><gut flora><gut microbe community><gut microbial community><gut microbial composition><gut microbial consortia><gut microbiota><gut microbiotic><gut microflora><host response><immune system response><immunoresponse><in vivo><intestinal flora><intestinal microbiota><intestinal microflora><intestinal tract microflora><large cell Diffuse non-Hodgkin's lymphoma><lymphatic fluid><malignancy><mesenteric lymph node><mesentery lymph node><microbial consortia><microbial flora><microbiota><microflora><mucosa associated lymphoid tissue><mucosa associated lymphoid-tissue><mucosa-associated lymphoid tissue><multispecies consortia><mutant><neoplasm/cancer><novel><old animals><overexpress><overexpression><pathway><plasmocyte><precancer><precancerous><premalignant><prevent><preventing><programs><response><secondary lymph organ><secondary lymphatic organ><secondary lymphoid organ><social role><somatic hypermutation><thymus derived lymphocyte><transcriptional profiling><tumor><tumorigenesis>
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Jason Williams

NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES

Exploratory lead · 24/100
Large award
$1,531,842
FY 2025

Project Title

Mass Spectrometry Identification

Grant Number:

1ZICES102488-18

Activity Code:

ZIC

Mechanism:

Intramural Research

Agency:

NIH

Why this may be worth a closer look

  • • Large budget suggests more room for personnel or project growth.

Project Abstract

A variety of service and collaborative projects for mass spectrometry analyses have been or are being carried out within the Mass Spectrometry Research Center with approximately 3000 samples analyzed from about 50 scientists representing about 25 principal investigators or core heads from 7 laborato...

Research Terms

<A1PI><Acetylation><Adrenal Cortex Hormones><Affect><Albumins><Amino Acids><Architecture><Arginine><Assay><Berger's Disease><Bifunctional Reagents><Binding><Bioassay><Biological Assay><Blood Platelets><Bright Disease><Cell Function><Cell Physiology><Cell Process><Cellular Function><Cellular Physiology><Cellular Process><Cellular biology><Chemicals><Chronic><Citrulline><Collaborations><Complex><Corticoids><Corticosteroids><Cross-Linking Reagents><Crosslinking Reagents><Cryo-electron Microscopy><Cryoelectron Microscopy><Deposit><Deposition><Development><Dexamethasone><Digestion><Disease><Disorder><Dissociation><Dysfunction><Electron Cryomicroscopy><Elements><Engineering / Architecture><Enzyme Gene><Enzymes><Estrus><Event><Exposure to><Functional disorder><Gene Expression><Glomerular Mesangium><Glomerular Mesangiums><Glomerulonephritis><Harvest><Herpesviridae><Herpesviruses><Heymann Nephritis><Human><Hypertensive Nephropathy><IGA Glomerulonephritis><IGA Nephropathy><IgA><IgA1><Immune Evasion><Immunoblotting><Immunoglobulin A><Infection><Intramural Research><Kidney Diseases><Knock-out><Knockout><L-Arginine><Label><Laboratories><Life Cycle><Life Cycle Stages><Link><Macromolecular Structure><Marrow platelet><Mass Photometry/Spectrum Analysis><Mass Spectrometry><Mass Spectroscopy><Mass Spectrum><Mass Spectrum Analyses><Mass Spectrum Analysis><Mediating><Metabolic Glycosylation><Methylation><Mice><Mice Mammals><Minnesota><Modern Man><Modification><Molecular><Molecular Interaction><Molecular Structure><Murine><Mus><NMR Spectrometer><NMR Spectroscopy><Nature><Nephropathy><Normal Cell><Osmosis><P50 Mechanism><P50 Program><Pathogenesis><Patients><Peptide Domain><Peptides><Phosphorylation><Physiopathology><Plasma Proteins><Platelets><Polymers><Post-Translational Modification Protein/Amino Acid Biochemistry><Post-Translational Modifications><Post-Translational Protein Modification><Post-Translational Protein Processing><Posttranslational Modifications><Posttranslational Protein Processing><Preparation><Prevention><Principal Investigator><Process><Protein Domains><Protein Modification><Protein Phosphorylation><Proteins><Proteome><Proteomics><Quaternary Protein Structure><R-Series Research Projects><R01 Mechanism><R01 Program><RNA Nucleases><RNA Processing><RNase><Radiolabeled><Reducing Agents><Reductants><Renal Disease><Renal Hypertension><Research><Research Grants><Research Project Grants><Research Projects><Ribonuclease Family Protein><Ribonucleases><Robin><Robin bird><Role><S element><Sampling><Scientist><Secondary Protein Structure><Services><Side><Signal Transduction Pathway><Site><Specialized Center><Stress><Structure><Structure of glomerular mesangium><Subcellular Process><Sulfur><System><Techniques><Tertiary Protein Structure><Thrombocytes><Toxicology><Tripcellim><Trypsin><Ubiquitilation><Ubiquitination><Ubiquitinoylation><Universities><Western Blotting><Western Immunoblotting><Work><alpha 1 Antiprotease><alpha 1-Antiproteinase><alpha 1-Antitrypsin><alpha 1-Antitrypsin Trypsin Inhibitor><alpha 1-Protease Inhibitor><alpha 1-Proteinase Inhibitor><alpha(1)-microglycoprotein><alpha-1-microglobulin><aminoacid><cell biology><chemical group><crosslink><cryo-EM><cryoEM><cryogenic electron microscopy><developmental><disulfide bond><enverin><estrous><experiment><experimental research><experimental study><experiments><focal glomerulonephritis><genomic RNA><glycosylation><herpes virus><hypertensive kidney><immune evasive><immunoglobulin A glomerulonephritis><immunoglobulin A nephropathy><insight><insoluble aggregate><kidney disorder><life course><lipidomics><mass spectrometer><mesangium><molecular mass><nuclear magnetic resonance spectroscopy><nuclease><particle><pathophysiology><polymer><polymeric><preparations><protein HC><protein aggregate><protein aggregation><protein blotting><protein complex><protein crosslink><protein expression><protein structure><protein structures><proteins structure><radiolabeling><radiologically labeled><renal disorder><response><segmental glomerulonephritis><small molecule><social role><structural biology><syncytin><thioether><ubiquination><ubiquitin conjugation><α1-Antitrypsin><α1-Proteinase Inhibitor><α1-microglobulin>
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Parsa Haque

UNIVERSITY OF PENNSYLVANIA, PHILADELPHIA, PA

Exploratory lead · 24/100
Active award
Career award
$94,653
FY 2026

Project Title

Plasticity of Kupffer Cells in Regulating T Cell Surveillance and Immunotherapy Efficacy in PDAC

Grant Number:

4K00CA294247-02

Activity Code:

K00

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

9/1/2024

End Date:

11/30/2029

Project Abstract

Project Summary Colorectal cancer (CRC) patients with a high body-mas index (BMI) have poor efficacy to chemotherapy, creating an urgent need to design targeted therapy for this group of cancer patients. During obesity, the excess visceral adipose tissue (AT) deposited around major organs in the abd...

Research Terms

<3-D><3-Dimensional><3D><Abdomen><Adipocytes><Adipose Cell><Adipose tissue><Agonist><Antigen Presentation Pathway><Antigen Processing and Presentation><Antigen-Presenting Cells><Antigens><B cell differentiation factor><B cell stimulating factor 2><B-Cell Differentiation Factor><B-Cell Differentiation Factor-2><B-Cell Stimulatory Factor-2><BCDF><BSF-2><BSF2><Biology><Body Tissues><Bp50><CD40><CDW40><Cancer Patient><Cancers><Cell Body><Cell Communication><Cell Communication and Signaling><Cell Death><Cell Function><Cell Interaction><Cell Mediated Immunology><Cell Membrane Lipids><Cell Physiology><Cell Process><Cell Signaling><Cell-Mediated Cytolysis><Cell-Mediated Immunity><Cell-Mediated Lympholysis><Cell-Mediated Lympholytic Cells><Cell-to-Cell Interaction><Cells><Cellular Cytotoxicity><Cellular Function><Cellular Immunity><Cellular Physiology><Cellular Process><Class I Antigens><Class I Genes><Class I Major Histocompatibility Antigens><Class II Genes><Colorectal Cancer><Communication><Complex Class 1><Cross Presentation><Cues><Cytolytic T-Cell><Cytotoxic T Cell><Cytotoxic T-Lymphocytes><Data><Deposit><Deposition><Development><Diet><Discontinuous Capillary><Distant><Environment><Enzyme Gene><Enzymes><Fat Cells><Fatty Tissue><Glycolysis><Goals><Grant><HLA Class II Genes><HPGF><Hepatic Cells><Hepatic Neoplasm Secondary><Hepatic Parenchymal Cell><Hepatic metastasis><Hepatocyte><Hepatocyte-Stimulating Factor><Histocompatibility Antigens Class I><Human><Hybridoma Growth Factor><IFN-beta 2><IFNB2><IL-6><IL6 Protein><Immune><Immune Evasion><Immune Surveillance><Immune mediated therapy><Immune response><Immunes><Immunity><Immunologic Surveillance><Immunologically Directed Therapy><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><Immunosurveillance><Immunotherapy><Impairment><Infiltration><Inflammation><Inflammatory><Interleukin-6><Intermediary Metabolism><Intracellular Communication and Signaling><Isomerase><Isomerase Gene><Kupffer Cells><Ligands><Lipocytes><Liver><Liver Cells><Liver secondaries><Liver secondary cancer><Lymphocyte Cytotoxicity><Lymphocytotoxicity><Lytotoxicity><MGC9013><MGI-2><MHC Class I><MHC Class I Genes><MHC Class I Molecule><MHC Class I Protein><MHC Class II><MHC Class II Genes><MHC class I antigen><Macrophage><Major Histocompatibility Complex Class 1><Malignant Cell><Malignant Neoplasms><Malignant Tumor><Mature Lipocyte><Mature fat cell><Mediating><Membrane Lipids><Metabolic><Metabolic Processes><Metabolism><Metastasis><Metastasize><Metastatic Lesion><Metastatic Mass><Metastatic Neoplasm><Metastatic Neoplasm to the Liver><Metastatic Tumor><Metastatic Tumor to the Liver><Metastatic malignant neoplasm to liver><Mice><Mice Mammals><Modern Man><Molecular><Murine><Mus><Myelogenous><Myeloid><Myeloid Cells><Myeloid Differentiation-Inducing Protein><Myeloid-derived suppressor cells><Mφ><Neoplasm Metastasis><Non obese><Nonobese><Obesity><Oncogenic><Organ><PDA model><PDAC Model><Pancreas Ductal Adenocarcinoma><Pancreatic Ductal Adenocarcinoma><Parents><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Phagocytes><Phagocytic Cell><Phagocytosis><Phenotype><Phosphates><Plasmacytoma Growth Factor><Pliability><Population><Position><Positioning Attribute><Productivity><Proteomics><Receptor Protein><Regulation><Regulatory T-Lymphocyte><Resistance><Role><STAT3><STAT3 gene><Secondary Neoplasm><Secondary Tumor><Shapes><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><Sinusoid><Sinusoidal Capillary><Stellate Sinusoidal Macrophage><Subcellular Process><Supporting Cell><T cell response><T-Cell Activation><T-Cell Depletion><T-Cells><T-Lymphocyte><T-cell depletion therapy><T-lymphocyte depletion therapy><TLR protein><TNFRSF5><TNFRSF5 gene><Testing><Therapeutic><Tissues><Toll-Like Receptor Family Gene><Toll-like receptors><Training><Treg><Tumor Antigens><Tumor Cell><Tumor Immunity><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><Tumor Promotion><Tumor-Associated Antigen><Upregulation><Vesicle><Visceral><accessory cell><activate T cells><adipose><adiposity><amebocyte><anti-tumor immunity><antitumor immunity><biological signal transduction><cancer antigens><cancer cell><cancer immunity><cancer immunology><cancer metastasis><cancer progression><cell mediated cytotoxicity><chemotherapy><colon cancer patients><colorectal cancer patients><colorectal cancer therapy><colorectal cancer treatment><combinatorial><corpulence><cytotoxicity><dectin 1><design><designing><developmental><diets><extracellular vesicles><hepatic body system><hepatic inflammation><hepatic organ system><host response><immune evasive><immune microenvironment><immune suppression><immune suppressive activity><immune suppressive function><immune system response><immune therapeutic approach><immune therapeutic interventions><immune therapeutic regimens><immune therapeutic strategy><immune therapy><immune-based therapies><immune-based treatments><immuno therapy><immunogen><immunoresponse><immunosuppressive activity><immunosuppressive function><immunosuppressive microenvironment><immunosuppressive myeloid cells><immunosuppressive response><immunosuppressive tumor microenvironment><improved outcome><in vivo><indexing><inflamed liver><inorganic phosphate><insight><interferon beta 2><intestinal tumorigenesis><killer T cell><liver inflammation><liver macrophage><liver metastases><malignancy><malignant liver neoplasm, specified as secondary><metastasis in the liver><metastasis to the liver><metastasize to the liver><metastatic cancer to liver><metastatic liver><metastatic liver neoplasm><mouse model><murine model><myeloid suppressor cells><myeloid-derived suppressive cells><necrocytosis><neoplasm immunology><neoplasm progression><neoplasm/cancer><neoplastic cell><neoplastic progression><novel><overexpress><overexpression><p50><pancreatic ductal adenocarcinoma model><parent><pathogen><patient oriented outcomes><pliable><programs><receptor><recruit><regulatory T-cells><release factor><resistance to therapy><resistant><resistant to therapy><response><restraint><secondary liver malignancy><secondary malignant liver neoplasm><social role><spheroids><suppressive myeloid cells><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment><therapeutic resistance><therapeutic target><therapy resistant><three dimensional><thymus derived lymphocyte><treatment resistance><tumor><tumor cell metastasis><tumor growth><tumor immune microenvironment><tumor immunology><tumor progression><tumor-immune system interactions><tumor-specific antigen><tumorigenic><white adipose tissue><yellow adipose tissue><β-Glucans>
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Linda Mac Pherson Bradley

SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE, LA JOLLA, CA

Exploratory lead · 22/100
Recent
Active award
$209,674
FY 2026

Project Title

Immune Checkpoint Blockade Targeting the Novel PSGL-1/VISTA Axis for Pancreatic Cancer

Grant Number:

5R21CA293150-02

Activity Code:

R21

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

3/10/2025

End Date:

2/28/2027

Project Abstract

Project Summary The goal of this project is to develop a novel immunotherapy to treat PDAC based on blockade of PSGL-1 (P- selectin glycoprotein ligand-1), to identify the attendant cellular and transcriptional changes in tumors comprising high vs low T cell infiltration, and to determine whether re...

Research Terms

<Address><Anti-CD40><Antitumor Response><B7-H1><Binding><Biological Markers><Bp50><CD152><CD152 Antigen><CD152 Gene><CD162 antigen><CD274><CD4 Cells><CD4 Positive T Lymphocytes><CD4 T cells><CD4 helper T cell><CD4 lymphocyte><CD4+ T-Lymphocyte><CD4-Positive Lymphocytes><CD40><CD62P Antigens><CD8 Cell><CD8 T cells><CD8 lymphocyte><CD8+ T cell><CD8+ T-Lymphocyte><CD8-Positive Lymphocytes><CD8-Positive T-Lymphocytes><CDW40><CTLA 4><CTLA-4 Gene><CTLA4><CTLA4 gene><CTLA4-TM><Cancers><Cell Body><Cell Communication and Signaling><Cell Line><Cell Signaling><CellLine><Cells><Checkpoint inhibitor><Clinical><Clinical Treatment Moab><Cytotoxic T-Lymphocyte Protein 4><Cytotoxic T-Lymphocyte-Associated Antigen 4><Cytotoxic T-Lymphocyte-Associated Protein 4><Cytotoxic T-Lymphocyte-Associated Serine Esterase-4><Data><Development><Exhibits><Failure><Frequencies><GEM model><GEMM model><GMP-140><Gene Transcription><GeneHomolog><Generalized Growth><Generations><Genetic><Genetic Transcription><Genetically Engineered Mouse><Glycoproteins><Goals><Growth><Homolog><Homologous Gene><Homologue><Human><Immune><Immune Cell Activation><Immune checkpoint inhibitor><Immune mediated therapy><Immune response><Immunes><Immunobiology><Immunochemical Immunologic><Immunocompetent><Immunoglobulin Domain><Immunoglobulin-Like Domain><Immunologic><Immunological><Immunologically><Immunologically Directed Therapy><Immunologics><Immunophysiology><Immunotherapy><Implant><In Vitro><Infiltration><Inflammation><Intervention><Intracellular Communication and Signaling><KPC genetically-engineered mouse><KPC model><KPC mouse><KPC murine><LECAM-3><LSL-KrasG12D/+LSL-Trp53R172H/+Pdx-1-Cre><LSL-KrasG12D/+LSL-p53R172H/+Pdx-1-Cre><Ligands><Link><MGC9013><Malignant Melanoma><Malignant Neoplasms><Malignant Pancreatic Neoplasm><Malignant Tumor><Malignant neoplasm of pancreas><Mediating><Melanoma><Metastasis><Metastasis to the Lung><Metastasize><Metastatic Lesion><Metastatic Mass><Metastatic Neoplasm><Metastatic Neoplasm to the Lung><Metastatic Tumor><Metastatic Tumor to the Lung><Mice><Mice Mammals><Modality><Modern Man><Molecular Fingerprinting><Molecular Interaction><Molecular Profiling><Monoclonal Antibodies><Murine><Mus><Neoplasm Metastasis><Outcome><P-Selectin><P-selectin glycoprotein ligand-1><P-selectin ligand protein><PD 1><PD-1><PD-1 blockade><PD-L1><PD1><PD1 blockade><PDA model><PDAC Model><PDAC cancer cell><PDAC cell><PDL-1><PSGL-1><Pancreas Cancer><Pancreatic Cancer><Patients><Phenotype><Platelet alpha-Granule Membrane Protein><Population><Pre-Clinical Model><Preclinical Models><Prognosis><Programmed Cell Death 1 Ligand 1><Programmed Death Ligand 1><RNA Expression><Receptor Protein><Refractory><Resistance><Role><Sampling><Secondary Neoplasm><Secondary Tumor><Signal Transduction><Signal Transduction Systems><Signaling><Site><Strains Cell Lines><Suppressor Cells><Suppressor-Effector T-Cells><Suppressor-Effector T-Lymphocytes><T Suppressor Cell><T cell differentiation><T cell infiltration><T cell response><T-Cell Activation><T-Cells><T-Lymphocyte><T4 Cells><T4 Lymphocytes><T8 Cells><T8 Lymphocytes><TNFRSF5><TNFRSF5 gene><Teff cell><Testing><Therapeutic><Tissue Growth><Transcription><Tumor Cell><Tumor Immunity><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><activate T cells><anti-PD-1 blockade><anti-PD1 blockade><anti-tumor immunity><anti-tumor response><antitumor immunity><bio-markers><biologic marker><biological signal transduction><biomarker><cancer immunity><cancer metastasis><cancer microenvironment><check point blockade><checkpoint blockade><chemotherapy><cultured cell line><cytotoxic T-lymphocyte antigen 4><developmental><effector T cell><exhaust><exhaustion><genetically engineered mouse model><genetically engineered murine model><host response><immune activation><immune check point blockade><immune check point inhibitor><immune checkpoint blockade><immune competent><immune microenvironment><immune system response><immune therapeutic approach><immune therapeutic interventions><immune therapeutic regimens><immune therapeutic strategy><immune therapy><immune-based therapies><immune-based treatments><immuno therapy><immunoresponse><immunosuppressive microenvironment><immunosuppressive tumor microenvironment><implantation><improved><lung metastasis><mAbs><malignancy><metastasize to the lung><molecular profile><molecular signature><monoclonal Abs><mouse model><murine model><neoplasm/cancer><neoplastic cell><new approaches><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel><novel approaches><novel strategies><novel strategy><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><ontogeny><p50><pancreatic cancer patients><pancreatic ductal adenocarcinoma cell><pancreatic ductal adenocarcinoma model><pancreatic malignancy><patients with pancreatic cancer><pharmacologic><pre-clinical study><preclinical study><progenitor-like cell><prognostic><programmed cell death 1><programmed cell death ligand 1><programmed cell death protein 1><programmed cell death protein ligand 1><programmed death 1><protein death-ligand 1><pulmonary metastasis><receptor><refractory cancer><resistant><resistant cancer><response><self-renew><self-renewal><single cell analysis><sle2><social role><stem-like cell><suppressor T lymphocyte><systemic lupus erythematosus susceptibility 2><thymus derived lymphocyte><tumor><tumor cell metastasis><tumor growth><tumor immune microenvironment><tumor microenvironment><tumor-immune system interactions>
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Quyen Ngoc Do

UT SOUTHWESTERN MEDICAL CENTER, DALLAS, TX

Exploratory lead · 20/100
Solid budget
Active award
$467,542
FY 2025

Project Title

Deep learning-based regional radiomics analysis in placenta accreta spectrum evaluation

Grant Number:

1R21HD119601-01

Activity Code:

R21

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/15/2025

End Date:

7/31/2027

Project Abstract

Project Summary Placenta Accreta Spectrum (PAS) is a serious obstetric condition characterized by abnormal adherence of the placenta to the uterine wall, leading to significant maternal morbidity and mortality during delivery. The increasing incidence of PAS correlates with the rise in cesarean deli...

Research Terms

<3rd trimester><Abdominal Delivery><Abnormal placentation><Accuracy of Diagnosis><Address><Adherence><Adoption><Affect><Anatomic Sites><Anatomic structures><Anatomy><Area><Assessment instrument><Assessment tool><Biomedical Engineering><Bleeding><C section><Cells Placenta-Tissue><Cesarean><Cesarean section><Childbirth><Cicatrix><Clinical><Clinical Data><Collaborations><Counseling><Data Bases><Data Set><Databases><Decidua><Decidua Graviditas><Development><Diagnosis><Diagnostic><Discipline of obstetrics><Disease><Disorder><Early Diagnosis><Echography><Echotomography><Ensure><Environment><Evaluation><Exhibits><Fetal health><General Radiology><Gestation><Goals><Health><Hemorrhage><High-Risk Pregnancy><Hysterectomy><Image><Incidence><Institution><Invaded><Investigators><Label><Last Trimester><Life><Location><MR Imaging><MR Tomography><MRI><MRI Scans><MRIs><Magnetic Resonance><Magnetic Resonance Imaging><Magnetic Resonance Imaging Scan><Manuals><Maternal Health><Maternal Mortality><Measures><Medical Imaging><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Medical Ultrasound><Medical center><Methods><Morbidity><Morbidity - disease rate><NMR Imaging><NMR Tomography><Normal Placentoma><Nuclear Magnetic Resonance Imaging><Obstetrics><Operative Procedures><Operative Surgical Procedures><Oranges><Otomy><Outcome><P50 Mechanism><P50 Program><Pathologic><Pathology><Patient Care><Patient Care Delivery><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Pelvic><Pelvic Region><Pelvis><Placenta><Placenta Accreta><Placenta Embryonic Tissue><Placentome><Position><Positioning Attribute><Post-partum Hemorrhage><Postpartum Hemorrhage><Predicting Risk><Pregnancy><Pregnancy Complications><Process><Radiology><Radiology Specialty><Research><Research Personnel><Research Resources><Researchers><Resources><Risk><Risk Assessment><Role><Scanning><Scars><Severities><Shapes><Site><Specialized Center><Standardization><Surgical><Surgical Interventions><Surgical Procedure><Surgical complication><Surgical incisions><Testing><Texture><Third Pregnancy Trimester><Third Trimester><Time><Training><Ultrasonic Imaging><Ultrasonogram><Ultrasonography><Ultrasound Diagnosis><Ultrasound Medical Imaging><Ultrasound Test><Uterus><Validation><Woman><Work><Zeugmatography><auto-segmentation><automated algorithm><automated segmentation><automatic algorithm><automatic segmentation><autosegmentation><bio-engineered><bio-engineers><bioengineering><biological engineering><biomedical referral center><blood loss><care for patients><care of patients><caring for patients><child birth><clinical decision-making><cohort><complications during pregnancy><computer based prediction><data base><data warehouse><deep learning><deep learning algorithm><deep learning based model><deep learning method><deep learning model><deep learning strategy><developmental><diagnostic accuracy><diagnostic ultrasound><early detection><fetal><forecasting risk><high risk><image-based method><imaging><imaging method><imaging modality><improved><incision><indexing><innovate><innovation><innovative><interest><maternal death><maternal morbidity><maternal outcome><mortality><mother outcome><multidisciplinary><novel><obstetric care><open source><patient oriented outcomes><predict risk><predict risks><predicted risk><predicted risks><predicting risks><predictive modeling><predictive risk><predictive tools><predicts risk><pregnancy-related complications><prenatal><prospective><radiomics><referral center><risk prediction><risk predictions><segmentation algorithm><severe maternal morbidity><social role><sonogram><sonography><sound measurement><surgery><surgery complication><tool><ultrasound><ultrasound imaging><ultrasound scanning><unborn><validations><womb>
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Gregg Wildenberg

UNIVERSITY OF CHICAGO, CHICAGO, IL

Exploratory lead · 20/100
Solid budget
Active award
$464,903
FY 2025

Project Title

Synaptic development of the retinogeniculate pathway

Grant Number:

1R21EY036568-01A1

Activity Code:

R21

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/30/2025

End Date:

9/29/2027

Project Abstract

PROJECT SUMMARY Throughout childhood, individual neurons that make up our brain form connections, or circuits, between each other. These circuits guide the flow of activity across our brain for proper functioning. A fascinating feature of the brain is that it’s believed that both our genetics and ou...

Research Terms

<0-11 years old><ASD><Age><Animals><Autism><Autistic Disorder><Axon><Birth Defects><Body Tissues><Bp50><Brain><Brain Nervous System><CD40><CDW40><Cell Body><Cells><Child><Child Youth><Childhood><Children (0-21)><Cholera Enterotoxin CT><Cholera Exotoxin><Cholera Toxin><Choleragen><Confocal Microscopy><Congenital Abnormality><Congenital Anatomical Abnormality><Congenital Defects><Congenital Deformity><Congenital Malformation><Cranial Nerve II><Data><Data Analyses><Data Analysis><Data Set><Dendrites><Development><Developmental Process><Diameter><Early Infantile Autism><Electric Conductivity><Electrical Conductivity><Electron Microscopy><Electrophysiology><Electrophysiology (science)><Embryo><Embryonic><Encephalon><Ensure><Environment><Equilibrium><Evaluation><Eye><Eyeball><Ferrets><Fluorescence Light Microscopy><Fluorescence Microscopy><Gametes><Generalized Growth><Genetic><Geniculate Bodies><Geniculate body structure><Germ Cells><Germ-Line Cells><Goals><Growth><Human><Image><Individual><Infantile Autism><Kanner's Syndrome><Label><Learning><Left><Life><MGC9013><Mammalia><Mammals><Measurement><Metathalamus><Methods><Mice><Mice Mammals><Modeling><Modern Man><Molecular><Morphology><Murine><Mus><Neonatal><Nerve Cells><Nerve Unit><Neural Cell><Neurocyte><Neurodevelopmental Disability><Neurodevelopmental Disorder><Neurological Development Disorder><Neurons><Neurophysiology / Electrophysiology><Neurosciences><Optic Nerve><Pathway interactions><Pattern><Population><Process><Property><Reproductive Cells><Retinal Ganglion Cells><Role><Second Cranial Nerve><Sex Cell><Sight><Stimulus><Surgical sutures><Sutures><Synapses><Synaptic><System><TNFRSF5><TNFRSF5 gene><Technology><Testing><Time><Tissue Growth><Tissues><Tracer><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><Vision><Visual><Visualization><ages><autism spectral disorder><autism spectrum disorder><autistic spectrum disorder><balance><balance function><comparative><data interpretation><developmental><electrical conductance><electrical property><electrophysiological><experience><experiment><experimental research><experimental study><experiments><fascinate><fluorophore><geniculate nucleus><imaging><initial cell><kids><light microscopy><model organism><monocular><monocular deprivation><myelination><neonatal brain><neonatal brain development><neural circuit><neural circuitry><neurocircuitry><neurodevelopmental disease><neuronal><ontogeny><p50><pathway><pediatric><physical model><postnatal><retinal ganglion><retinogeniculate><sexual cell><social role><synapse><synaptic circuit><synaptic circuitry><tool><visual deprivation><visual function><youngster>
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George V Aslanidi

UNIVERSITY OF MINNESOTA, MINNEAPOLIS, MN

Exploratory lead · 20/100
Solid budget
Active award
$437,250
FY 2025

Project Title

Mingling life imaging and cell subpopulations expression analysis in NHP lungs targeted with exosome associated double AAV vectors

Grant Number:

1R21AI182508-01A1

Activity Code:

R21

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

6/25/2025

End Date:

5/31/2027

Project Abstract

PROJECT SUMMARY Gene therapy provides a universal therapeutic option for patients with genetic or acquired disorders that can potentially benefit a broad patient populations. However, up to date several gene therapy clinical trials for lung- specific diseases, while well addressing safety concerns, ...

Research Terms

<AAV vector><AAV-based vector><Ab response><Acceleration><Address><Adeno-Associated Viruses><Air><Anatomic Sites><Anatomic structures><Anatomy><Animal Model><Animal Models and Related Studies><Antibody Formation><Antibody Production><Architecture><Autopsy><Basal Cell><Biodistribution><Biological><Biology><Blood Sample><Blood specimen><CD8 Cell><CD8 T cells><CD8 lymphocyte><CD8+ T cell><CD8+ T-Lymphocyte><CD8-Positive Lymphocytes><CD8-Positive T-Lymphocytes><Cell Body><Cell Mediated Immunology><Cell-Mediated Immunity><Cells><Cellular Immunity><Clinical><Complex><DNA Therapy><Dependoparvovirus><Dependovirus><Development><Disease><Disorder><Drugs><Engineering / Architecture><Ensure><Epithelial Cells><FDA approved><Filtration><Filtration Fractionation><Funding><Future><Gene Delivery><Gene Expression><Gene Expression Monitoring><Gene Expression Pattern Analysis><Gene Expression Profiling><Gene Therapy Vectors><Gene Transduction Agent><Gene Transduction Vectors><Gene Transfer><Gene Transfer Clinical><Genetic><Genetic Intervention><Genomic DNA><Goals><Grant><Hereditary Disease><Human><Humoral Immunities><Image><Immune response><Immunology><In Vitro><Inborn Genetic Diseases><Inflammatory><Infrastructure><Inhalation><Inhaling><Inherited disorder><Kinetics><Lead><Life><Liquid substance><Lung><Lung Diseases><Lung Respiratory System><Mediating><Medication><Methods><Mice><Mice Mammals><Mink><Minnesota><Modality><Modeling><Modern Man><Mucous body substance><Mucus><Murine><Mus><NHP models><NIS Gene><NIS protein><Neobalaenidae><Outcome><P50 Mechanism><P50 Program><Pathway interactions><Patient Participation><Patients><Pattern><Pb element><Penetration><Pharmaceutical Preparations><Physiology><Play><Population><Preparation><Process><Production><Progenitor Cells><Public Health><Publishing><Pulmonary Diseases><Pulmonary Disorder><Receptor Protein><Respiratory Epithelium><Role><SLC5A5><SLC5A5 gene><Safety><Serotyping><Solute Carrier Family 5 (Sodium Iodide Symporter), Member 5><Specialized Center><Structure of respiratory epithelium><System><T cell response><T8 Cells><T8 Lymphocytes><Testing><Therapeutic><Time><Toxic effect><Toxicities><Transcript Expression Analyses><Transcript Expression Analysis><Tropism><Ultracentrifugation><Viral><Viral Vector><Virion><Virus Particle><Whales><acute toxicity><adeno associated virus group><adeno-associated viral vector><adeno-associated virus vector><airway epithelial stem cells><airway epithelium><airway progenitor><airway stem cells><analyze gene expression><antibody biosynthesis><antibody-based immunity><basal progenitor><basal stem cell><biologic><cell transduction><cell type><cellular transduction><clinical development><clinical practice><clinical relevance><clinically relevant><commercial scale manufacturing><delivery vector><delivery vehicle><design><designing><developmental><disease model><disease of the lung><disorder model><disorder of the lung><drug/agent><exosome><extracellular vesicles><fluid><gDNA><gene expression analysis><gene expression assay><gene repair therapy><gene testing><gene therapy><gene therapy clinical trial><gene-based testing><gene-based therapy><gene-based treatment><gene-directed therapy><gene-targeted therapy><gene-targeted treatment><genetic testing><genetic therapy><genomic therapy><heavy metal Pb><heavy metal lead><hereditary disorder><heritable disorder><host response><hybrid gene><imaging><imaging in vivo><immune system response><immunogenicity><immunoglobulin biosynthesis><immunoresponse><improved><in vivo Model><in vivo imaging><inborn error><infrastructure development><inherited diseases><inherited genetic disease><inherited genetic disorder><innovate><innovation><innovative><liquid><lung development><lung disorder><lung progenitor><lung stem cell><lung tissue stem cell><lung-specific stem cell><manufacturing ramp-up><manufacturing scale-up><model of animal><mouse model><mucous><multidisciplinary><murine model><necropsy><neutralizing antibody><new approaches><next generation><non-human primate><nonhuman primate><nonhuman primate models><novel><novel approaches><novel strategies><novel strategy><pathway><patient population><postmortem><pre-clinical research><preclinical research><preparations><progenitor cells in the lung><progenitor-like cell><progenitors in the lung><pulmonary progenitor><pulmonary stem cell><receptor><respiratory progenitor><respiratory stem cell><respiratory tract epithelium><safety and feasibility><scale up><scale up batch><scale up production><social role><sodium-iodide symporter><stem cells><stem cells in the airway><stem cells in the lung><stem-like cell><therapeutic agent development><therapeutic development><therapeutic transgene><transcriptional profiling><transduced cells><transduction efficiency><transgene expression><treatment strategy><upscale manufacturing><vector>
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HIDEKAZU TSUKAMOTO

UNIVERSITY OF SOUTHERN CALIFORNIA, Los Angeles, CA

Exploratory lead · 20/100
Solid budget
Active award
$433,811
FY 2025

Project Title

Integrative Liver Cell Core

Grant Number:

5R24AA012885-25

Activity Code:

R24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

6/15/2001

End Date:

5/31/2027

Project Abstract

Abstract The Integrative Liver Cell Core (ILCC) strives to serve the scientific community of alcoholic liver disease (ALD) and cirrhosis via specialized services of isolating 6 different liver cell types (hepatocytes, HC; hepatic macrophages, HM; hepatic stellate cells, HSC; sinusoidal endothelial ...

Research Terms

<Absolute ethanol><Alcohol Chemical Class><Alcohol abuse><Alcohol associated hepatitis><Alcohol hepatitis><Alcohol induced hepatitis><Alcohol related hepatitis><Alcoholic><Alcoholic Hepatitis><Alcoholic Liver Diseases><Alcoholic steatohepatitis><Alcoholism><Alcohols><Animals><Blood Neutrophil><Blood Polymorphonuclear Neutrophil><Boozer><California><Cell Body><Cell Fate Control><Cell Fate Regulation><Cell Isolation><Cell Lineage><Cell Segregation><Cell Separation><Cell Separation Technology><Cells><Cellular biology><Chronic><Cirrhosis><Collaborations><Communication><Communities><Country><Couples><Dependent drinker><Diet><Disclosure><Disease><Disorder><ETOH><Endothelial Cells><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><EtOH abuse><Ethanol><Ethanol-induced hepatitis><Ethyl Alcohol><Evolution><Fatty Liver><Fibroblasts><Fibrosis><Fluorescence Activated Cell Sorting Fractionation><Fluorescence-Activated Cell Sorting><Fluorescence-Activated Cell Sortings><Funding><Genes><Genetic><Goals><Grain Alcohol><Grant><Hepatic><Hepatic Cancer><Hepatic Cells><Hepatic Cirrhosis><Hepatic Disorder><Hepatic Neoplasms><Hepatic Parenchymal Cell><Hepatic Stellate Cell><Hepatocyte><Hybrids><Inflammation><Information Disclosure><Infusion><Infusion procedures><Injury to Liver><Institution><Investigators><Ito Cell><KI mice><Knock-in><Knock-in Mouse><Liver><Liver Cells><Liver Cirrhosis><Liver Fibrosis><Liver Steatosis><Liver diseases><Liver neoplasms><Macrophage><Macrophage Activation><Malignant neoplasm of liver><Marrow Neutrophil><Medical Research><Mesenchymal><Mesothelial Cell><Metabolic><Methylcarbinol><Mice><Mice Mammals><Modeling><Molecular><Murine><Mus><Mφ><NASH><NIAAA><National Institute on Alcohol Abuse and Alcoholism><Neutrophilic Granulocyte><Neutrophilic Leukocyte><Oncogenesis><Outcome><Pathogenesis><Pathologic><Phenotype><Physiology><Play><Polymorphonuclear Cell><Polymorphonuclear Leukocytes><Polymorphonuclear Neutrophils><Preparation><Procedures><Publications><Reaction><Reporter><Research><Research Personnel><Research Resources><Research Support><Researchers><Resources><Role><Sampling><Scientific Publication><Scientist><Services><Stem Cell like><Techniques><Testing><Vitamin A><alcohol co-abuse><alcohol induced hepatic injury><alcohol induced liver disorder><alcohol induced liver injury><alcohol problem><alcohol related liver disease><alcohol-associated liver disease><alcohol-induced hepatic dysfunction><alcohol-induced liver disease><alcohol-induced liver dysfunction><alcohol-mediated liver dysfunction><alcohol-mediated liver injury><alcohol-related liver disease><alcoholic liver injury><career><cell bank><cell biology><cell repository><cell sorting><cell type><cellular repository><cirrhotic><clinical relevance><clinically relevant><conditional knock-out><conditional knockout><diets><disease model><disorder model><epigenetically><ethanol abuse><ethanol induced hepatic injury><ethanol induced liver disorder><ethanol induced liver injury><ethanol liver disease><ethanol-induced hepatic dysfunction><ethanol-induced liver disease><ethanol-induced liver dysfunction><ethanol-mediated liver dysfunction><ethanol-mediated liver injury><feeding><fibrotic liver><gain of function><hazardous alcohol use><hepatic body system><hepatic damage><hepatic disease><hepatic fibrosis><hepatic injury><hepatic neoplasia><hepatic neoplasm><hepatic organ system><hepatic steatosis><hepatic tumor><hepatopathy><hepatosteatosis><infusions><innovate><innovation><innovative><interest><knockin><knockin mice><liver cancer><liver damage><liver disorder><liver injury><liver malignancy><liver tumor><malignant liver tumor><migration><mouse model><murine model><neutrophil><new drug target><new druggable target><new pharmacotherapy target><new therapeutic target><new therapy target><non-alcohol induced steatohepatitis><non-alcoholic steato-hepatitis><non-alcoholic steatohepatitis><nonalcoholic steato-hepatitis><nonalcoholic steatohepatitis><novel><novel drug target><novel druggable target><novel pharmacotherapy target><novel therapeutic target><novel therapy target><preparations><problem alcohol use><problem drinker><problem drinking><problematic alcohol consumption><problematic alcohol use><progenitor><progenitor capacity><progenitor cell like><progenitor-like><promoter><promotor><response><social role><stem cell characteristics><stem-like><stemness><synergism><tumor initiation><tumorigenesis>
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Remi Buisson

UNIVERSITY OF CALIFORNIA-IRVINE, IRVINE, CA

Exploratory lead · 20/100
Solid budget
Active award
$431,750
FY 2025

Project Title

NF-KB regulation by the DNA damage response

Grant Number:

1R21ES036190-01A1

Activity Code:

R21

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

1/9/2025

End Date:

1/8/2027

Project Abstract

PROJECT SUMMARY NF-κB is a transcription factor activated in response to environmental genotoxic stress and important for driving DNA damage-induced inflammation. However, mechanisms linking DNA damage that occur in the nucleus to NF-κB activation in the cytoplasm remain poorly understood. NF-κB is ...

Research Terms

<ATM Protein><ATM Serine/Threonine Protein Kinase><ATM kinase><ATM protein kinase><Acetylation><Actinic Rays><Acute><Affect><Apoptosis><Apoptosis Pathway><Ataxia Telangiectasia Mutated><Ataxia Telangiectasia Protein><Ataxia-Telangiectasia-Mutated protein kinase><Automobile Driving><Basal Transcription Factor><Basal transcription factor genes><Benzene><Benzol><Benzole><Bp50><Bypass><CD40><CDW40><Cancers><Cell Aging><Cell Body><Cell Communication and Signaling><Cell Cycle Arrest><Cell Death><Cell Nucleus><Cell Protection><Cell Senescence><Cell Signaling><Cells><Cellular Aging><Cellular Senescence><Cellular injury><Chemicals><Chronic><Complex><Cyclohexatriene><Cytoplasm><Cytoprotection><DNA><DNA Damage><DNA Damage Repair><DNA Double Strand Break><DNA Injury><DNA Repair><DNA Repair Pathway><DNA lesion><DNA mutation><DNA-Dependent RNA Polymerases><DNA-Directed RNA Polymerase><Data><Defect><Deoxyribonucleic Acid><Ecological impact><Environmental Factor><Environmental Impact><Environmental Risk Factor><Esteroproteases><Exposure to><Formaldehyde><Formic Aldehyde><Foundations><Gene Expression><Gene Transcription><General Transcription Factor Gene><General Transcription Factors><Genetic Change><Genetic Diseases><Genetic Transcription><Genetic defect><Genetic mutation><Genome Instability><Genome Stability><Genomic Instability><Genomic Stability><Genotoxic Stress><Goals><I Kappa B A><I Kappa B-Alpha><I kappa B-alpha protein><IFN><IKB-Alpha><IKappaB><IKappaB-Alpha><IKappaB/MAD-3><IL-1 alpha><IL-1-a><IL-1A><IL-1alpha><IL-1ra><IL-1α><IL1 febrile inhibitor><IL1-Alpha><IL1-α><IL1A Protein><IL1F1><IL1R><IL1R1><IL1R1 gene><IL1RA><IL1RN><IRAK><IRAK1><IRAK1 gene><IkappaBalpha><Immune><Immune signaling><Immunes><Immunoglobulin Enhancer-Binding Protein><Immunomodulation><Inflammation><Inflammatory><Inflammatory Response><Innate Immune Response><Innate Immune System><Innate Immunity><Interferons><Interleukin 1alpha><Interleukin-1 Receptor Antagonist><Interleukin-1 Receptor-Associated Kinase 1><Interleukin-1 alpha><Intracellular Communication and Signaling><IκBα><Kinases><Knowledge><Lead><Link><MAD-3 protein><MAD3><MAD3 inhibitor><MGC9013><Major Histocompatibility Complex Enhancer-Binding Protein MAD3><Malignant Neoplasms><Malignant Tumor><Mediating><Methyl Aldehyde><Mutation><NF-Kappa B Inhibitor Alpha><NF-kB><NF-kappa B><NF-kappaB><NF-kappaB inhibitor alpha><NFKB><Native Immunity><Natural Immunity><Non-Specific Immunity><Nonspecific Immunity><Nuclear><Nuclear Factor Kappa-B Inhibitor><Nuclear Factor kappa B><Nuclear Factor of Kappa Light Chain Gene Enhancer in B Cells Inhibitor><Nuclear Factor of Kappa Light Chain Gene Enhancer in B Cells Inhibitor, Alpha><Nuclear Transcription Factor NF-kB><Nucleotide Excision Repair><Nucleus><Oxomethane><Pathway interactions><Patients><Pb element><Peptidases><Peptide Hydrolases><Phosphotransferase Gene><Phosphotransferases><Physiologic><Physiological><Play><Preinterleukin 1 Alpha><Programmed Cell Death><Protease Gene><Proteases><Proteinases><Proteins><Proteolytic Enzymes><RNA Expression><RNA Polymerases><Radiation><Regulation><Replicative Senescence><Research><Role><Signal Pathway><Signal Transduction><Signal Transduction Systems><Signaling><Site><Stress><TNF Receptor-Associated Factor 6 Gene><TNFRSF5><TNFRSF5 gene><TRAF6><TRAF6 gene><Testing><Tobacco smoke><Topoisomerase Inhibitors><Transcription><Transcription Factor NF-kB><Transcription Factor Proto-Oncogene><Transcription factor genes><Transphosphorylases><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><UV irradiated><UV irradiation><UV light><UV radiation><UV rays><Ubiquitin Ligase Component Gene><Ubiquitin Ligase Gene><Ultraviolet Rays><Unscheduled DNA Synthesis><age associated disease><age associated disorder><age associated impairment><age dependent disease><age dependent disorder><age dependent impairment><age related human disease><age-related disease><age-related disorder><age-related impairment><anakinra><ataxia telangiectasia mutated protein><biological signal transduction><cell damage><cell injury><cellular damage><chemotherapeutic agent><chemotherapeutic compounds><chemotherapeutic drugs><chemotherapeutic medications><cytoprotective><damage to cells><driving><environmental agent><environmental risk><genetic condition><genetic disorder><genome mutation><heavy metal Pb><heavy metal lead><immune modulation><immune regulation><immunologic reactivity control><immunomodulatory><immunoregulation><immunoregulatory><inhibitor><injury to cells><interleukin 1 receptor antagonist protein><kappa B Enhancer Binding Protein><malignancy><mouse model><murine model><necrocytosis><neoplasm/cancer><nuclear factor kappa beta><p50><p65><pathway><pelle><prevent><preventing><recruit><repair><repaired><replicative aging><response><social role><transcription factor><ubiquitin ligase><ultra violet irradiation><ultra violet light><ultra violet radiation><ultra violet rays><ultraviolet irradiation><ultraviolet light><ultraviolet radiation><urine IL-1 inhibitor><urine interleukin 1 inhibitor><urine-derived IL1 inhibitor>
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Ivana Tallerico Croghan

MAYO CLINIC ROCHESTER, ROCHESTER, MN

Exploratory lead · 20/100
Solid budget
Active award
$411,939
FY 2025

Project Title

Using Vagal Nerve Stimulation in Conjunction with NRT for Smoking Cessation

Grant Number:

1R21CA302802-01

Activity Code:

R21

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/4/2025

End Date:

8/31/2027

Project Abstract

PROJECT SUMMARY This research proposal aims to evaluate vagal nerve stimulation (VNS) as a novel treatment for Tobacco Use Disorder (TUD), targeting improved smoking cessation rates. Cigarette smoking remains a major public health issue, leading to over 400,000 premature deaths annually in the U.S. ...

Research Terms

<Abstinence><Action Potentials><Acute><Address><Adherence><Amfebutamone><Animal Model><Animal Models and Related Studies><Autonomic nervous system><Awareness><Biochemical><Bupropion><COPD><Carbon Monoxide><Cardiac><Cardiac Diseases><Cardiac Disorders><Cell Communication and Signaling><Cell Signaling><Cephalalgia><Cephalgia><Cephalodynia><Cessation Research><Cessation of life><Characteristics><Chronic><Chronic Cluster Headache><Chronic Obstruction Pulmonary Disease><Chronic Obstructive Lung Disease><Chronic Obstructive Pulmonary Disease><Cigarette Smoker><Ciliary Neuralgia><Clinic><Clinical><Clinical Cooperative Groups><Clinical Trial Groups><Clinical Trials><Clinical Trials Cooperative Group><Cluster Headache><Cluster Headache Syndrome><Combined Modality Therapy><Cranial Nerve X><Cranial Pain><Crohn disease><Crohn's><Crohn's disease><Crohn's disorder><Data><Death><Decentralization><Devices><Disease><Disorder><Double-Blind Method><Double-Blind Study><Double-Blinded><Double-Masked Method><Double-Masked Study><Drug Therapy><Drugs><Dysfunction><Environment><Epilepsy><Epileptic Seizures><Epileptics><FDA approved><Frequencies><Functional disorder><Goals><Granulomatous Enteritis><Head Pain><Headache><Health><Health Care Costs><Health Costs><Heart><Heart Diseases><Histamine Cephalgia><Horton Syndrome><Implant><Intracellular Communication and Signaling><Investigation><Irritable Bowel Syndrome><Irritable Colon><Link><Literature><Malignant Tumor of the Lung><Malignant neoplasm of lung><Measures><Medication><Mental Depression><Migraine><Migraine Headache><Monitor><Morbidity><Morbidity - disease rate><Mucous Colitis><Multimodal Therapy><Multimodal Treatment><Nerve><Nerve Cells><Nerve Unit><Neural Cell><Neuralgic Migraine><Neurocyte><Neurons><Nicotine Dependence><Nicotine Replacement Therapy><Nicotine Skin Patch><Obesity><Operative Procedures><Operative Surgical Procedures><P50 Mechanism><P50 Program><Pain Control><Pain Therapy><Pain management><Participant><Passive Smoke Exposure><Pathway interactions><Patients><Pharmaceutical Agent><Pharmaceutical Preparations><Pharmaceuticals><Pharmacologic Substance><Pharmacological Substance><Pharmacological Treatment><Pharmacotherapy><Phase><Phase 2 Clinical Trials><Phase II Clinical Trials><Physiopathology><Pilot Projects><Pneumogastric Nerve><Prevalence><Preventative treatment><Preventive treatment><Public Health><Pulmonary Cancer><Pulmonary malignant Neoplasm><Randomized><Regulation><Relapse><Reporting><Research><Research Project Summaries><Research Proposals><Retreatment><Risk><Seizure Disorder><Severities><Signal Transduction><Signal Transduction Systems><Signaling><Smoker><Smoking><Smoking Behavior><Smoking Cessation Intervention><Specialized Center><Sphenopalatine Neuralgias><Stress><Surgical><Surgical Interventions><Surgical Procedure><Techniques><Tenth Cranial Nerve><Testing><Therapeutic><Tobacco Consumption><Tobacco Dependence><Tobacco Use Disorder><Tobacco use><Transcranial magnetic stimulation><United States><Vagus Nerve><Vagus nerve structure><Vidian Neuralgias><Visit><Wellbutrin><addiction><addictive disorder><adiposity><afferent nerve><alcohol use disorder><biological signal transduction><buproprion><cease smoking><chronic obstructive pulmonary disorder><cigarette smoking><cigarette use><combination therapy><combined modality treatment><combined treatment><compare treatment><corpulence><craving><depression><design><designing><determine efficacy><drug intervention><drug seeking behavior><drug treatment><drug/agent><effective therapy><effective treatment><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><eleocolitis><endothelial dysfunction><environmental tobacco smoke exposure><epilepsia><epileptogenic><ethanol use disorder><evaluate efficacy><examine efficacy><experience><exposure to ETS><exposure to SHS><exposure to environmental tobacco smoke><exposure to secondhand smoke><exposure to tobacco smoke><head ache><heart disorder><heart rate variability><improved><innovate><innovation><innovative><long-term abstinence><lung cancer><migraine therapy><migraine treatment><model of animal><mortality><multi-modal therapy><multi-modal treatment><neural control><neural regulation><neuromodulation><neuromodulatory><neuronal><neuronal excitability><neuroregulation><nicotine addiction><nicotine dependent><nicotine patch><nicotine replacement><nicotine treatment><novel><opiate use disorder><opioid use disorder><pain intervention><pain treatment><pathophysiology><pathway><patient centered><patient oriented><pharmaceutical><pharmaceutical intervention><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><phase II protocol><pilot study><portability><pre-clinical study><preclinical study><premature><prematurity><prevent relapse><preventable death><preventable mortality><primary end point><primary endpoint><prolonged abstinence><quit smoking><randomisation><randomization><randomly assigned><re-treatment><recruit><regional enteritis><relapse prevention><response><second hand smoke exposure><secondary outcome><secondhand smoke exposure><secondhand tobacco smoke exposure><sensory nerve><side effect><smoking abstinence><smoking cessation><smoking cessation treatment><smoking initiation><spastic colon><stop smoking><success><surgery><sustained abstinence><telehealth><tobacco abuse><tobacco addiction><tobacco dependent><tobacco disorder><tobacco product use><treatment comparison><varenicline>
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Ryan Thomas Hurt

MAYO CLINIC ROCHESTER, ROCHESTER, MN

Exploratory lead · 20/100
Solid budget
Active award
$411,939
FY 2025

Project Title

Using Vagal Nerve Stimulation in Conjunction with NRT for Smoking Cessation

Grant Number:

1R21CA302802-01

Activity Code:

R21

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/4/2025

End Date:

8/31/2027

Project Abstract

PROJECT SUMMARY This research proposal aims to evaluate vagal nerve stimulation (VNS) as a novel treatment for Tobacco Use Disorder (TUD), targeting improved smoking cessation rates. Cigarette smoking remains a major public health issue, leading to over 400,000 premature deaths annually in the U.S. ...

Research Terms

<Abstinence><Action Potentials><Acute><Address><Adherence><Amfebutamone><Animal Model><Animal Models and Related Studies><Autonomic nervous system><Awareness><Biochemical><Bupropion><COPD><Carbon Monoxide><Cardiac><Cardiac Diseases><Cardiac Disorders><Cell Communication and Signaling><Cell Signaling><Cephalalgia><Cephalgia><Cephalodynia><Cessation Research><Cessation of life><Characteristics><Chronic><Chronic Cluster Headache><Chronic Obstruction Pulmonary Disease><Chronic Obstructive Lung Disease><Chronic Obstructive Pulmonary Disease><Cigarette Smoker><Ciliary Neuralgia><Clinic><Clinical><Clinical Cooperative Groups><Clinical Trial Groups><Clinical Trials><Clinical Trials Cooperative Group><Cluster Headache><Cluster Headache Syndrome><Combined Modality Therapy><Cranial Nerve X><Cranial Pain><Crohn disease><Crohn's><Crohn's disease><Crohn's disorder><Data><Death><Decentralization><Devices><Disease><Disorder><Double-Blind Method><Double-Blind Study><Double-Blinded><Double-Masked Method><Double-Masked Study><Drug Therapy><Drugs><Dysfunction><Environment><Epilepsy><Epileptic Seizures><Epileptics><FDA approved><Frequencies><Functional disorder><Goals><Granulomatous Enteritis><Head Pain><Headache><Health><Health Care Costs><Health Costs><Heart><Heart Diseases><Histamine Cephalgia><Horton Syndrome><Implant><Intracellular Communication and Signaling><Investigation><Irritable Bowel Syndrome><Irritable Colon><Link><Literature><Malignant Tumor of the Lung><Malignant neoplasm of lung><Measures><Medication><Mental Depression><Migraine><Migraine Headache><Monitor><Morbidity><Morbidity - disease rate><Mucous Colitis><Multimodal Therapy><Multimodal Treatment><Nerve><Nerve Cells><Nerve Unit><Neural Cell><Neuralgic Migraine><Neurocyte><Neurons><Nicotine Dependence><Nicotine Replacement Therapy><Nicotine Skin Patch><Obesity><Operative Procedures><Operative Surgical Procedures><P50 Mechanism><P50 Program><Pain Control><Pain Therapy><Pain management><Participant><Passive Smoke Exposure><Pathway interactions><Patients><Pharmaceutical Agent><Pharmaceutical Preparations><Pharmaceuticals><Pharmacologic Substance><Pharmacological Substance><Pharmacological Treatment><Pharmacotherapy><Phase><Phase 2 Clinical Trials><Phase II Clinical Trials><Physiopathology><Pilot Projects><Pneumogastric Nerve><Prevalence><Preventative treatment><Preventive treatment><Public Health><Pulmonary Cancer><Pulmonary malignant Neoplasm><Randomized><Regulation><Relapse><Reporting><Research><Research Project Summaries><Research Proposals><Retreatment><Risk><Seizure Disorder><Severities><Signal Transduction><Signal Transduction Systems><Signaling><Smoker><Smoking><Smoking Behavior><Smoking Cessation Intervention><Specialized Center><Sphenopalatine Neuralgias><Stress><Surgical><Surgical Interventions><Surgical Procedure><Techniques><Tenth Cranial Nerve><Testing><Therapeutic><Tobacco Consumption><Tobacco Dependence><Tobacco Use Disorder><Tobacco use><Transcranial magnetic stimulation><United States><Vagus Nerve><Vagus nerve structure><Vidian Neuralgias><Visit><Wellbutrin><addiction><addictive disorder><adiposity><afferent nerve><alcohol use disorder><biological signal transduction><buproprion><cease smoking><chronic obstructive pulmonary disorder><cigarette smoking><cigarette use><combination therapy><combined modality treatment><combined treatment><compare treatment><corpulence><craving><depression><design><designing><determine efficacy><drug intervention><drug seeking behavior><drug treatment><drug/agent><effective therapy><effective treatment><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><eleocolitis><endothelial dysfunction><environmental tobacco smoke exposure><epilepsia><epileptogenic><ethanol use disorder><evaluate efficacy><examine efficacy><experience><exposure to ETS><exposure to SHS><exposure to environmental tobacco smoke><exposure to secondhand smoke><exposure to tobacco smoke><head ache><heart disorder><heart rate variability><improved><innovate><innovation><innovative><long-term abstinence><lung cancer><migraine therapy><migraine treatment><model of animal><mortality><multi-modal therapy><multi-modal treatment><neural control><neural regulation><neuromodulation><neuromodulatory><neuronal><neuronal excitability><neuroregulation><nicotine addiction><nicotine dependent><nicotine patch><nicotine replacement><nicotine treatment><novel><opiate use disorder><opioid use disorder><pain intervention><pain treatment><pathophysiology><pathway><patient centered><patient oriented><pharmaceutical><pharmaceutical intervention><pharmacological intervention><pharmacological therapy><pharmacology intervention><pharmacology treatment><pharmacotherapeutics><phase II protocol><pilot study><portability><pre-clinical study><preclinical study><premature><prematurity><prevent relapse><preventable death><preventable mortality><primary end point><primary endpoint><prolonged abstinence><quit smoking><randomisation><randomization><randomly assigned><re-treatment><recruit><regional enteritis><relapse prevention><response><second hand smoke exposure><secondary outcome><secondhand smoke exposure><secondhand tobacco smoke exposure><sensory nerve><side effect><smoking abstinence><smoking cessation><smoking cessation treatment><smoking initiation><spastic colon><stop smoking><success><surgery><sustained abstinence><telehealth><tobacco abuse><tobacco addiction><tobacco dependent><tobacco disorder><tobacco product use><treatment comparison><varenicline>
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Yu-Tsueng Liu

AEROCYTEK, INC., SAN DIEGO, CA

Exploratory lead · 20/100
Solid budget
Active award
$400,000
FY 2025

Project Title

Point-of-care autologous CAR-T cell manufacturing

Grant Number:

1R43CA298530-01

Activity Code:

R43

Mechanism:

SBIR/STTR

Agency:

NIH

Start Date:

9/18/2025

End Date:

8/31/2026

Project Abstract

The successful implementation of chimeric antigen receptor (CAR)-T cell therapies relies on effective cell product manufacturing. This process not only affects the cost, safety and efficacy of the final product but also plays a crucial role in ensuring broader patient access to this innovative treat...

Research Terms

<Address><Adoptive Cellular Immunotherapy><Adoptive Immunotherapy><Affect><Allogenic><Apheresis><Autologous><Automation><Bioequivalence><Biological><Blood><Blood Component Removal><Blood Reticuloendothelial System><Blood Volume><Bone Marrow Grafting><Bone Marrow Transplant><Bone Marrow Transplantation><CAR T cell therapy><CAR T cells><CAR T therapy><CAR modified T cells><CAR-T><CAR-Ts><CD19><CD19 gene><CD8 Cell><CD8 T cells><CD8 lymphocyte><CD8+ T cell><CD8+ T-Lymphocyte><CD8-Positive Lymphocytes><CD8-Positive T-Lymphocytes><Cancers><Cell Body><Cell Communication><Cell Culture Techniques><Cell Function><Cell Interaction><Cell Physiology><Cell Process><Cell Therapy><Cell-to-Cell Interaction><Cells><Cellular Function><Cellular Physiology><Cellular Process><Cellular biology><Charge><Clinical><Clinical Equivalency><Complex><Contrast Agent><Contrast Drugs><Contrast Media><Development><Devices><Dose><Eligibility><Eligibility Determination><Engineering><Ensure><European><Gene Transfer><Generic Equivalency><Goals><HSC transplantation><Hemapheresis><Hematologic Cancer><Hematologic Malignancies><Hematologic Neoplasms><Hematological Malignancies><Hematological Neoplasms><Hematological Tumor><Hematopoietic Cancer><Hematopoietic Stem Cell Transplant><Hematopoietic Stem Cell Transplantation><History><Hour><Hybrids><Immunologic Subtyping><Immunophenotyping><Infrastructure><Investments><Laboratory Research><Lipids><Logistics><Malignant Hematologic Neoplasm><Malignant Neoplasms><Malignant Tumor><Marrow Transplantation><Methodology><Methods><Microbubbles><Modeling><Multiple Myeloma><Oncologist><Oncology><Oncology Cancer><P50 Mechanism><P50 Program><Patients><Phase><Pheresis><Physiologic><Physiological><Plasma-Cell Myeloma><Play><Procedures><Process><Production><Protocol><Protocol Screening><Protocols documentation><Quality Control><Radiopaque Media><Reagent><Recording of previous events><Reporting><Research Resources><Resources><Role><Safety><Societies><Solid Neoplasm><Solid Tumor><Specialized Center><Standardization><Stem Cell like><Subcellular Process><Survey Instrument><Surveys><Syringes><System><T cell based immune therapy><T cell based therapeutics><T cell based therapy><T cell directed therapies><T cell immune therapy><T cell immunotherapy><T cell targeted therapeutics><T cell therapy><T cell treatment><T cell-based immunotherapy><T cell-based treatment><T cells for CAR><T cellular immunotherapy><T cellular therapy><T lymphocyte based immunotherapy><T lymphocyte based therapy><T lymphocyte therapeutic><T lymphocyte treatment><T-Cell Activation><T-Cells><T-Lymphocyte><T-cell therapeutics><T-cell transfer therapy><T8 Cells><T8 Lymphocytes><Techniques><Technology><Testing><Therapeutic><Therapeutic Equivalency><Time><Training and Infrastructure><Transportation><Tumor Burden><Tumor Load><Viral><Waiting Lists><activate T cells><adoptive T cell transfer><adoptive T lymphocyte transfer><adoptive T-cell therapy><adoptive cell immunotherapy><biologic><bioprocess><blood stem cell transplantation><cell based intervention><cell biology><cell culture><cell cultures><cell mediated intervention><cell mediated therapies><cell-based therapeutic><cell-based therapy><cellular therapeutic><cellular therapy><chimeric antigen T cell receptor><chimeric antigen receptor (CAR) T cell therapy><chimeric antigen receptor (CAR) T cells><chimeric antigen receptor T><chimeric antigen receptor T cell therapy><chimeric antigen receptor T cells><chimeric antigen receptor T therapy><chimeric antigen receptor fusion protein T-cells><chimeric antigen receptor modified T cells><cost><developmental><drug bioequivalence><drug bioequivalent><engineered T cells><fabrication cost><flexibility><flexible><full scale manufacturing><genetically engineered T-cells><hematopoietic cell transplantation><hematopoietic cellular transplantation><hematopoietic progenitor cell transplantation><histories><immunological synapse><innovate><innovation><innovative><invention><large scale manufacturing><large scale production><lentiviral-transduced><lentivirally transduced><lentivirus transduced><malignancy><manufacture><manufacturing capabilities><manufacturing capacity><manufacturing cost><manufacturing process><manufacturing systems><mass production><mortality><mouse model><murine model><myeloma><myelomatosis><neoplasm/cancer><point of care><pre-clinical><pre-clinical study><preclinical><preclinical study><preservation><progenitor capacity><progenitor cell like><progenitor-like><self-renew><self-renewal><social role><stem cell characteristics><stem-like><stemness><therapeutic T-cell platform><therapeutic outcome><therapy outcome><thymus derived lymphocyte><transgenic T- cells><tumor><ultrasound><user-friendly><virological synapse><waitlist>
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Yulia Surovtseva

YALE UNIVERSITY, NEW HAVEN, CT

Exploratory lead · 20/100
Solid budget
Active award
$374,613
FY 2025

Project Title

Echo Acoustic Liquid Handler to Support Biomedical Research and Discovery

Grant Number:

1S10OD038347-01

Activity Code:

S10

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

5/15/2025

End Date:

5/14/2026

Project Abstract

PROJECT SUMMARY / ABSTRACT Ability to transfer very small, nanoliter amounts of small molecules or genomic probes between microplates is necessary for all medium- and high throughput screening applications. Echo acoustic liquid handlers use sound waves to move 2.5 nanoliter droplets of liquid from s...

Research Terms

<Acoustics><Address><Adopted><Amentia><Applications Grants><Area><Basic Research><Basic Science><Biomedical Research><Cancers><Cardiac Diseases><Cardiac Disorders><Clinical Research><Clinical Study><Collection><Communicable Diseases><Core Facility><Data><Dementia><Destinations><Drug Screening><Dystonia><Faculty><Foundations><Funding><Future><Gene Library><Generations><Genomics><Grant Proposals><Health><Heart Diseases><High Throughput Assay><Human><Infectious Diseases><Infectious Disorder><Infrastructure><Institution><Investigators><Laboratories><Liquid substance><Malignant Neoplasms><Malignant Tumor><Manufacturer><Medical Research><Modern Man><Molecular><Muscle Dystonia><NIH><National Institutes of Health><Neurodevelopmental Disorder><Neurological Development Disorder><P50 Mechanism><P50 Program><Pharmaceutical Agent><Pharmaceuticals><Pharmacologic Substance><Pharmacological Substance><Publications><Research><Research Personnel><Researchers><Scientific Publication><Series><Source><Specialized Center><System><Technology><Therapeutic><Translational Research><Translational Science><United States National Institutes of Health><Universities><Vascular Diseases><Vascular Disorder><Work><assay development><base><bases><blood vessel disorder><commercial launch><commercial product launch><drug discovery><experience><flexibility><flexible><fluid><genetic library><heart disorder><high throughput screening><innovate><innovation><innovative><instrument><liquid><malignancy><member><nano litre><nanoliter><nanolitre><neoplasm/cancer><neurodevelopmental disease><pharmaceutical><programs><screening><screening services><screenings><small molecule><sound><translation research><translational investigation><vascular dysfunction><vasculopathy>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

John F Neumaier

SEATTLE INST FOR BIOMEDICAL/CLINICAL RES, SEATTLE, WA

Exploratory lead · 20/100
Solid budget
Active award
$359,433
FY 2025

Project Title

GRABbing Serotonin During Fear

Grant Number:

1R21MH137701-01A1

Activity Code:

R21

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/24/2025

End Date:

9/23/2027

Project Abstract

Serotonin plays a critical role in responding to potentially threatening stimuli and modulating the serotonin system can either exacerbate or ameliorate fear responses to subsequent encounters with fear-producing stimuli. Medications that inhibit serotonin reuptake are often used for stress disorder...

Research Terms

<5-HT><5-HT Receptors><5-HT pathway><5-HT system><5-Hydroxytryptamine><5-Hydroxytryptamine Receptors><5HT><AAV vector><AAV-based vector><Affect><Amygdala><Amygdaloid Body><Amygdaloid Nucleus><Amygdaloid structure><Animals><Anxiety><Area><Behavior><Behavioral><Bioinformatics><Biology><Biosensor><Brain><Brain Nervous System><Brain region><CMV><CRISPR><CRISPR/Cas system><Cell Communication and Signaling><Cell Nucleus><Cell Signaling><Chaperone><Chronic stress><Clustered Regularly Interspaced Short Palindromic Repeats><Code><Coding System><Complex><Cues><Cytomegalovirus><DNA cassette><Drugs><Effectiveness><Emotional><Emotions><Encephalon><Endocrine Gland Secretion><Enteramine><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Event><Extinction><FK506 binding protein 5><FKBP51><FKBP54><Fear><Feedback><Female><Fiber><Fright><Future><Gene Action Regulation><Gene Expression><Gene Expression Regulation><Gene Regulation><Gene Regulation Process><Genes><Glucocorticoid Receptor><Glucocorticoids><HCMV><Hippophaine><History><Hormonal><Hormones><Impairment><Intracellular Communication and Signaling><Investigation><Knock-out><Knockout><Learning><LoxP-flanked allele><Measurement><Measures><Mediating><Medication><Memory><Methods><Mice><Mice Mammals><Molecular Chaperones><Monitor><Murine><Mus><Nerve Cells><Nerve Unit><Neural Cell><Neurocyte><Neuronal Dysfunction><Neurons><Nucleus><Opsin><Output><PTSD><Pharmaceutical Preparations><Photometry><Physiologic><Physiological><Physiology><Play><Position><Positioning Attribute><Post-Traumatic Neuroses><Post-Traumatic Stress Disorders><Posttraumatic Neuroses><Procedures><Production><Proteins><Receptor Protein><Receptor Signaling><Recording of previous events><Research><Resistance><Retrieval><Rod-Opsin><Role><SSRI><SSRIs><Salivary Gland Viruses><Selective Serotonin Reuptake Inhibitor><Selective serotonin re-uptake inhibitor><Serotonergic System><Serotonin><Signal Transduction><Signal Transduction Systems><Signaling><Steroid Compound><Steroid Receptors><Steroids><Stimulus><Stress><System><Technology><Testing><Therapeutic><Therapeutic Hormone><Time><Trauma><Viral Vector><adeno-associated viral vector><adeno-associated virus vector><amygdaloid nuclear complex><anti-depressant agent><anti-depressant drugs><anti-depressants><anti-depressive agents><biological adaptation to stress><biological sensor><biological signal transduction><burden of disease><burden of illness><cell type><cohort><compare to control><comparison control><conditioned fear><coping><cytomegalovirus group><deep sequencing><disease burden><dorsal raphe nucleus><drug/agent><emotional symptom><enhancer cassette><epigenetically><experiment><experimental research><experimental study><experiments><expression cassette><extracellular><fear conditioning><floxed><floxed allele><gene cassette><genetic cassette><histories><innervation><innovate><innovation><innovative><integration cassette><life span><lifespan><male><mouse model><murine model><nerve supply><neural dysfunction><neuronal><novel><optogenetics><overexpress><overexpression><post-trauma stress disorder><postsynaptic><posttrauma stress disorder><presynaptic><promoter cassette><reactioncrisis><receptor><reporter cassette><resilience><resilient><resilient to stress><resistance cassette><resistant><response><reuptake><selectable cassette><selection cassette><serotonergic pathway><serotonin pathway><serotonin receptor><serotonin reuptake inhibitor><serotonin system><social role><steroid hormone receptor><stop cassette><stress disorder><stress related disorder><stress resilience><stress resiliency><stress response><stress symptom><stressreaction><tacrolimus binding protein 5><therapeutic target><tool><transcription cassette><transcriptional cassette><transgene cassette><translatome><traumatic neurosis><vector><vector control><♀><♂>
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OLAF STUVE

UT SOUTHWESTERN MEDICAL CENTER, DALLAS, TX

Exploratory lead · 20/100
Solid budget
Active award
$300,000
FY 2025

Project Title

Immune Checkpoint-Engineered oligodendrocytes as treatment for multiple sclerosis

Grant Number:

1R56AI188482-01A1

Activity Code:

R56

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/10/2025

End Date:

8/31/2026

Project Abstract

Immune checkpoints play a key role in regulating hemostasis and maintaining self-tolerance, including in the human autoimmune disease of the central nervous system: multiple sclerosis (MS). We previously employed metabolic glycoengineering and biorthogonal click chemistry to bioengineer immune check...

Research Terms

<Address><Agonist><Antibodies><Atrophic Arthritis><Autoimmune Diseases><Autologous><B7-H1><BM Stem Cell><BM derived progenitor><BM progenitor><BM- derived Stem Cells><Biomedical Engineering><Bone Marrow Stem Cell><Bone Marrow progenitor><Bp50><Brain><Brain Nervous System><CD154><CD274><CD40><CD40L><CD40LG><CD86><CD86 gene><CDW40><CNS autoimmune disease><CNS autoimmunity><Cell Body><Cells><Chemistry><Clinical><Data><Disseminated Sclerosis><EAE><Encephalon><Engineering><Experimental Allergic Encephalitis><Experimental Allergic Encephalomyelitis><Experimental Animal Model><Experimental Autoimmune Encephalitis><Experimental Autoimmune Encephalomyelitis><Formulation><Funding><Glia><Glial Cells><Glycoengineering><Harvest><Health Care><Hemostasis><Hemostatic function><Human><Immune><Immune Tolerance><Immune reaction><Immunes><Immunochemical Immunologic><Immunologic><Immunologic Tolerance><Immunological><Immunologically><Immunologics><Incubated><Kolliker's reticulum><Ligands><Literature><MGC9013><MS treatment><Metabolic><Methods><Mice><Mice Mammals><Modeling><Modern Man><Multiple Sclerosis><Murine><Mus><Nanotechnology><Neurilemma Cell><Neurilemmal Cell><Neuroglia><Neuroglial Cells><Non-neuronal cell><Nonneuronal cell><Oligodendrocytes><Oligodendrocytus><Oligodendroglia><Oligodendroglia Cell><PD-L1><PDL-1><Pathway interactions><Phase><Play><Progenitor Cells><Programmed Cell Death 1 Ligand 1><Programmed Death Ligand 1><Protocol><Protocols documentation><Publications><Rheumatoid Arthritis><Schwann Cells><Scientific Publication><Self Tolerance><Source><T-Cells><T-Lymphocyte><TNFRSF5><TNFRSF5 gene><TNFSF5><TNFSF5 gene><TRAP Gene><Technology><Therapeutic><Time><Translating><Treatment Efficacy><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><Vaccines><Work><autoimmune condition><autoimmune disorder><autoimmune encephalomyelitis><autoimmune reactivity><autoimmunity disease><autoreactivity><bio-engineered><bio-engineers><bioengineering><biological engineering><bone marrow derived progenitor><bone marrow derived stem cells><bone marrow stromal cell><bone marrow stromal stem cell><central nervous system autoimmune disease><central nervous system autoimmunity><clinical investigation><develop a vaccine><develop vaccines><development of a vaccine><exhaustion><iPS><iPSC><iPSCs><immune check point><immune checkpoint><immune system tolerance><immune unresponsiveness><immunecheckpoint><immunological paralysis><immunoreaction><improved><in vivo><induced pluripotent cell><induced pluripotent stem cell><inducible pluripotent cell><inducible pluripotent stem cell><innovate><innovation><innovative><insight><insular sclerosis><interest><intervention efficacy><mouse model><multiple sclerosis therapy><multiple sclerosis treatment><murine model><nano tech><nano technology><nano-technological><nanotech><nanotechnological><neonatal mice><nerve cement><new approaches><novel><novel approaches><novel strategies><novel strategy><p50><pathway><prevent><preventing><programmed cell death ligand 1><programmed cell death protein ligand 1><protein death-ligand 1><rheumatic arthritis><stem cells><success><theories><therapeutic efficacy><therapeutic vaccine><therapy efficacy><thymus derived lymphocyte><treatment vaccines><vaccine development><vaccine for the treatment><vaccine for treatment>
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Andrew Zhuang Wang

UT SOUTHWESTERN MEDICAL CENTER, DALLAS, TX

Exploratory lead · 20/100
Solid budget
Active award
$300,000
FY 2025

Project Title

Immune Checkpoint-Engineered oligodendrocytes as treatment for multiple sclerosis

Grant Number:

1R56AI188482-01A1

Activity Code:

R56

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/10/2025

End Date:

8/31/2026

Project Abstract

Immune checkpoints play a key role in regulating hemostasis and maintaining self-tolerance, including in the human autoimmune disease of the central nervous system: multiple sclerosis (MS). We previously employed metabolic glycoengineering and biorthogonal click chemistry to bioengineer immune check...

Research Terms

<Address><Agonist><Antibodies><Atrophic Arthritis><Autoimmune Diseases><Autologous><B7-H1><BM Stem Cell><BM derived progenitor><BM progenitor><BM- derived Stem Cells><Biomedical Engineering><Bone Marrow Stem Cell><Bone Marrow progenitor><Bp50><Brain><Brain Nervous System><CD154><CD274><CD40><CD40L><CD40LG><CD86><CD86 gene><CDW40><CNS autoimmune disease><CNS autoimmunity><Cell Body><Cells><Chemistry><Clinical><Data><Disseminated Sclerosis><EAE><Encephalon><Engineering><Experimental Allergic Encephalitis><Experimental Allergic Encephalomyelitis><Experimental Animal Model><Experimental Autoimmune Encephalitis><Experimental Autoimmune Encephalomyelitis><Formulation><Funding><Glia><Glial Cells><Glycoengineering><Harvest><Health Care><Hemostasis><Hemostatic function><Human><Immune><Immune Tolerance><Immune reaction><Immunes><Immunochemical Immunologic><Immunologic><Immunologic Tolerance><Immunological><Immunologically><Immunologics><Incubated><Kolliker's reticulum><Ligands><Literature><MGC9013><MS treatment><Metabolic><Methods><Mice><Mice Mammals><Modeling><Modern Man><Multiple Sclerosis><Murine><Mus><Nanotechnology><Neurilemma Cell><Neurilemmal Cell><Neuroglia><Neuroglial Cells><Non-neuronal cell><Nonneuronal cell><Oligodendrocytes><Oligodendrocytus><Oligodendroglia><Oligodendroglia Cell><PD-L1><PDL-1><Pathway interactions><Phase><Play><Progenitor Cells><Programmed Cell Death 1 Ligand 1><Programmed Death Ligand 1><Protocol><Protocols documentation><Publications><Rheumatoid Arthritis><Schwann Cells><Scientific Publication><Self Tolerance><Source><T-Cells><T-Lymphocyte><TNFRSF5><TNFRSF5 gene><TNFSF5><TNFSF5 gene><TRAP Gene><Technology><Therapeutic><Time><Translating><Treatment Efficacy><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><Vaccines><Work><autoimmune condition><autoimmune disorder><autoimmune encephalomyelitis><autoimmune reactivity><autoimmunity disease><autoreactivity><bio-engineered><bio-engineers><bioengineering><biological engineering><bone marrow derived progenitor><bone marrow derived stem cells><bone marrow stromal cell><bone marrow stromal stem cell><central nervous system autoimmune disease><central nervous system autoimmunity><clinical investigation><develop a vaccine><develop vaccines><development of a vaccine><exhaustion><iPS><iPSC><iPSCs><immune check point><immune checkpoint><immune system tolerance><immune unresponsiveness><immunecheckpoint><immunological paralysis><immunoreaction><improved><in vivo><induced pluripotent cell><induced pluripotent stem cell><inducible pluripotent cell><inducible pluripotent stem cell><innovate><innovation><innovative><insight><insular sclerosis><interest><intervention efficacy><mouse model><multiple sclerosis therapy><multiple sclerosis treatment><murine model><nano tech><nano technology><nano-technological><nanotech><nanotechnological><neonatal mice><nerve cement><new approaches><novel><novel approaches><novel strategies><novel strategy><p50><pathway><prevent><preventing><programmed cell death ligand 1><programmed cell death protein ligand 1><protein death-ligand 1><rheumatic arthritis><stem cells><success><theories><therapeutic efficacy><therapeutic vaccine><therapy efficacy><thymus derived lymphocyte><treatment vaccines><vaccine development><vaccine for the treatment><vaccine for treatment>
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Andre Ballesteros-Tato

NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES

Exploratory lead · 18/100
Above-average budget
$917,532
FY 2025

Project Title

Tfh Cell Plasticity and Heterogeneity in Shaping Immune Responses to Allergy, Infection, and Tolerance

Grant Number:

1ZIAAI001403-01

Activity Code:

ZIA

Mechanism:

Intramural Research

Agency:

NIH

Why this may be worth a closer look

  • • Award size is strong enough to merit immediate review.

Project Abstract

T follicular helper (Tfh) cells are a subset of CD4⁺ T cells that support B cells within germinal centers (GCs)—specialized structures in lymphoid organs where B cells refine their antibodies and generate long-lived plasma cells and memory B cells. By providing key signals through molecules such as ...

Research Terms

<Ablation><Address><Allergens><Allergic><Allergic Disease><Allergic inflammation><Allergic to food><Allergy><Allergy to food><Antibodies><Antibody Response><Antigens><Atrophic Arthritis><Autoantibodies><Autoimmune Diseases><Autoimmune Status><Autoimmunity><Autoregulation><B blood cells><B cell><B cells><B-Cells><B-Lymphocytes><B-cell><Basal Transcription Factor><Basal transcription factor genes><Blood Plasma Cell><CD152><CD152 Antigen><CD152 Gene><CD154><CD4 Cells><CD4 Positive T Lymphocytes><CD4 T cells><CD4 helper T cell><CD4 lymphocyte><CD4+ T-Lymphocyte><CD4-Positive Lymphocytes><CD40L><CD40LG><CTLA 4><CTLA-4 Gene><CTLA4><CTLA4 deficiency><CTLA4 gene><CTLA4 haploinsufficiency><CTLA4-TM><Cell Body><Cell Communication and Signaling><Cell Compartmentation><Cell Compartmentations><Cell Differentiation><Cell Differentiation process><Cell Signaling><Cells><Cellular biology><Clinical Data><Co-Stimulator><Colitis><Collaborations><Complex><Costimulator><Cytotoxic T-Lymphocyte Protein 4><Cytotoxic T-Lymphocyte-Associated Antigen 4><Cytotoxic T-Lymphocyte-Associated Protein 4><Cytotoxic T-Lymphocyte-Associated Serine Esterase-4><Data><Development><Disease><Disorder><Dose><Dysfunction><Epidermal Thymocyte Activating Factor><Equilibrium><Exposure to><Failure><Food Allergy><Food Hypersensitivity><Foundations><Functional disorder><Future><General Transcription Factor Gene><General Transcription Factors><Generations><Germinal Center><Goals><Gut associated lymphoid tissue><Helper Cells><Helper T-Cells><Helper T-Lymphocytes><Helper-Inducer T-Cells><Helper-Inducer T-Lymphocyte><Heterogeneity><Homeostasis><Human><IL-2><IL2 Protein><IL21><IgE><Immune><Immune mediated therapy><Immune response><Immunes><Immunity><Immunoglobulin E><Immunologically Directed Therapy><Immunology><Immunomodulation><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><Immunotherapy><Impairment><Inducer Cells><Inducer T-Lymphocytes><Infection><Inflammation><Inflammatory Bowel Diseases><Inflammatory Bowel Disorder><Interleukin 2><Interleukin 2 Precursor><Interleukin II><Interleukin-2><Interleukine 2><Interleukine 2 Precursor><Interleukine II><Intervention><Intestinal><Intestines><Intracellular Communication and Signaling><Knowledge><Link><Lung><Lung Respiratory System><Lupus><Lupus Erythematosus Disseminatus><Lymphocyte Mitogenic Factor><Maps><Mediating><Memory><Memory B Cell><Memory B-Lymphocyte><Mitogenic Factor><Modeling><Modern Man><Modification><Molecular><Mucosa><Mucosal Tissue><Mucous Membrane><NIAID><NIDDK><National Institute of Allergy and Infectious Disease><National Institute of Diabetes and Digestive and Kidney Diseases><Nature><Outcome><P50 Mechanism><P50 Program><Pathogenicity><Pathology><Pathway interactions><Patients><Physiological Homeostasis><Physiopathology><Plasma Cells><Plasmacytes><Population><Pre-Clinical Model><Preclinical Models><Production><Recombinants><Regulatory T-Lymphocyte><Respiratory Disease><Respiratory System Disease><Respiratory System Disorder><Rheumatoid Arthritis><Role><SLE><Science><Shapes><Signal Transduction><Signal Transduction Systems><Signaling><Source><Specialized Center><Stem Cell like><Structure><Structure of germinal center of lymph node><Supporting Cell><System><Systemic Lupus Erythematosus><Systemic Lupus Erythematous><Systemic Lupus Erythmatosus><Systemic disease><T cell growth factor><T-Cell Growth Factor><T-Cell Stimulating Factor><T-Cells><T-Lymphocyte><T4 Cells><T4 Lymphocytes><TNFSF5><TNFSF5 gene><TRAP Gene><Teff cell><Th-2 Cell><Th2 Cells><Therapeutic><Therapeutic Effect><Thymocyte Stimulating Factor><Transcription Factor Proto-Oncogene><Transcription factor genes><Treg><Type 2 Helper Cell><Viral><Work><autoimmune antibody><autoimmune condition><autoimmune disorder><autoimmune reactivity><autoimmunity disease><autoreactive antibody><autoreactivity><balance><balance function><biological signal transduction><bowel><cell biology><cellular differentiation><chronic autoimmune disease><conditional knock-out><conditional knockout><cytokine><cytotoxic T-lymphocyte antigen 4><data modeling><desensitization><developmental><disseminated lupus erythematosus><draining lymph node><effective therapy><effective treatment><effector T cell><gastrointestinal><host response><immune modulation><immune regulation><immune suppression><immune suppressive activity><immune suppressive function><immune system response><immune therapeutic approach><immune therapeutic interventions><immune therapeutic regimens><immune therapeutic strategy><immune therapy><immune-based therapies><immune-based treatments><immuno therapy><immunogen><immunologic reactivity control><immunomodulatory><immunopathology><immunoregulation><immunoregulatory><immunoresponse><immunosuppressive activity><immunosuppressive function><immunosuppressive response><imprint><in vivo><inflammatory disease of the intestine><inflammatory disorder of the intestine><inhibitor><interleukin-21><intestinal autoinflammation><lupus prone mice><lymph organ><lymphatic organ><lymphoid organ><microbial consortia><microbial flora><microbiota><microflora><model of data><model the data><modeling of the data><mouse model><multispecies consortia><murine model><mutein 2><new therapeutic approach><new therapeutic intervention><new therapeutic strategies><new therapy approaches><new treatment approach><new treatment strategy><novel><novel therapeutic approach><novel therapeutic intervention><novel therapeutic strategies><novel therapy approach><pathophysiology><pathway><plasmocyte><preservation><prevent><preventing><progenitor capacity><progenitor cell like><progenitor-like><programs><rational design><recombinant Mut2 protein><regional lymph node><regulatory T-cells><respiratory><response><rheumatic arthritis><self reactive antibody><single cell analysis><social role><stem cell characteristics><stem-like><stemness><success><systemic autoimmunity><systemic lupus erythematosis><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment><thymus derived lymphocyte><tool><transcription factor>
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Demetrius Albanes

DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS

Exploratory lead · 18/100
Above-average budget
$690,581
FY 2025

Project Title

Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study

Grant Number:

1ZIACP010195-19

Activity Code:

ZIA

Mechanism:

Intramural Research

Agency:

NIH

Why this may be worth a closer look

  • • Award size is strong enough to merit immediate review.

Project Abstract

The ATBC Cohort Follow-up Study has been in place since 1994. Male smokers between the ages of 50 and 69 were recruited from southwestern Finland between April 1985 and June 1988. A total of 29,133 men were randomly assigned to one of four intervention groups: 50 mg/day alpha-tocopherol (as dl-alph...

Research Terms

<Active Follow-up><Age><All-Trans-Retinol><Anti-Infective vitamin><Antioxidants><Antixerophthalmic vitamin><Area><Axerophthol><Axerophtholum><Biochemical><Biological><Biological Markers><Biosterol><Bladder><Bladder Cancer><Bladder Urinary System><Blood Serum><Blood erythrocyte><Breast Cancer><Bronchi><CXR><Cancer Cause><Cancer Etiology><Cancer Intervention><Cancers><Capsules><Carbon><Carotenes and Carotenoids><Carotenoids><Categories><Caucasian><Caucasian Race><Caucasians><Caucasoid><Caucasoid Race><Cessation of life><Chest><Cigarette><Cohort Analyses><Cohort Analysis><Collaborations><Colon><Colon or Rectum><Colorectal><Colorectal Cancer><Data><Death><Diagnosis><Diet><Dietary Questionnaires><Dimensions><Disease><Disorder><EXTMR><Epidemiologic Research><Epidemiologic Studies><Epidemiological Studies><Epidemiology Research><Erythrocytes><Erythrocytic><Evaluation><Extramural><Extramural Activities><Film><Finland><Folate><Folic Acid><Follow-Up Studies><Followup Studies><Food><Freezing><GWA study><GWAS><Gastric Body Cancer><Gastric Cancer><Gastric Cardia Cancer><Gastric Fundus Cancer><Gastric Pylorus Cancer><Gene variant><Genetic><Genetic Polymorphism><Genome Scan><Genotype><Glial Cell Tumors><Glial Neoplasm><Glial Tumor><Glioma><Goals><Gonadal Steroid Hormones><Growth Agents><Growth Factor><Growth Substances><HDL Cholesterol><HDL Cholesterol Lipoproteins><Habits><Head and Neck><Head and neck structure><Health><High Density Lipoprotein Cholesterol><Human><Human Resources><Humulin R><Insulin><Intermediary Metabolism><International><Intervention><Investigation><Investigators><Kidney Cancer><Kidney Carcinoma><Lard-Factor><Lung><Lung Respiratory System><Malignant Bladder Neoplasm><Malignant Breast Neoplasm><Malignant Gastric Neoplasm><Malignant Gastric Tumor><Malignant Neoplasms><Malignant Pancreatic Neoplasm><Malignant Tumor><Malignant Tumor of the Bladder><Malignant Tumor of the Lung><Malignant neoplasm of lung><Malignant neoplasm of pancreas><Malignant neoplasm of prostate><Malignant neoplasm of urinary bladder><Malignant prostatic tumor><Manpower><Marrow erythrocyte><Measurement><Medical><Medical Records><Metabolic><Metabolic Processes><Metabolism><Modern Man><Molecular><NCI Organization><National Cancer Institute><Nested Case-Control Study><Neuroglial Neoplasm><Neuroglial Tumor><Novolin R><Nutrient><Nutrition><Nutritional><Occidental><Occupational><Oleovitamin A><Ophthalamin><P50 Mechanism><P50 Program><PLRA><Pancreas><Pancreas Cancer><Pancreatic><Pancreatic Cancer><Participant><Pathology><Phase><Phenotype><Placebos><Pleura><Pleural Tissue><Population Registers><Procedures><Productivity><Prospective Studies><Prostate><Prostate CA><Prostate Cancer><Prostate Gland><Prostate malignancy><Prostatic Gland><Proteins Growth Factors><Pteroylglutamic Acid><Public Health><Pulmonary Cancer><Pulmonary malignant Neoplasm><R-Series Research Projects><R01 Mechanism><R01 Program><Randomized><Randomized, Controlled Trials><Rectum><Red Blood Cells><Red Cell><Regular Insulin><Renal Cancer><Renal Carcinoma><Research><Research Grants><Research Personnel><Research Project Grants><Research Projects><Research Resources><Research Specimen><Researchers><Resources><Sampling><Se element><Selenium><Serum><Sex Hormones><Sex Steroid Hormones><Sham Treatment><Slide><Smoker><Smoking><Solatene><Specialized Center><Specimen><Stomach Cancer><Structure of nail of toe><Supplementation><Survey Instrument><Surveys><Testing><Thorace><Thoracic><Thoracic Radiography><Thorax><Tocopherol acetate><Toe Nail><Toenail><Trachea><Trachea Proper><Urinary Bladder Cancer><Urinary Bladder Malignant Tumor><VIT D><Visit><Vitamin A Alcohol><Vitamin D><Vitamin E><Vitamin E Acetate><Vitamin M><Vitamins><Whole Blood><active followup><ages><allelic variant><alpha-Lipoprotein Cholesterol><alpha-tocopherol acetate><alpha-tocopheryl acetate><attributable risk><beta,beta-Carotene><bio-markers><biologic><biologic marker><biomarker><blood corpuscles><cancer epidemiology><cancer prevention><cancer registry><capsule><carotenoid biosynthesis><case control><case-controlled><chest X ray><chest Xray><chest radiography><cohort><colorectum><d-alpha-Tocopherol acetate><d-alpha-tocopheryl acetate><design><designing><diet and cancer><dietary><diets><effectiveness testing><energy balance><epidemiologic investigation><epidemiology study><follow up><follow-up><followed up><followup><gastric malignancy><genetic analysis><genetic variant><genome wide association><genome wide association scan><genome wide association study><genome-wide scan><genomewide association scan><genomewide association study><genomewide scan><genomic variant><glial-derived tumor><gonadal steroids><group intervention><interest><intervention effect><lung cancer><lung radiography><male><malignancy><malignant breast tumor><malignant stomach neoplasm><malignant stomach tumor><men><metabolism measurement><metabolomics><metabonomics><neoplasm registry><neoplasm/cancer><neuroglia neoplasm><neuroglia tumor><nutritious><pancreatic malignancy><personnel><polymorphism><population based><post intervention><prevent><preventing><prostate cancer risk><radiographic chest image><radiographic lung image><randomisation><randomization><randomized control trial><randomly assigned><recruit><retinol><sex steroid><sham therapy><side effect><stomach fundus cancer><stomach pylorus cancer><thoracic radiogram><thorax radiography><tocopherolacetate-d-alpha><tocopheryl acetate><urinary bladder><vitamin Bc><web site><website><white race><whole genome association analysis><whole genome association study><whole-genome scan><windpipe><α-Tocopherol><β-Carotene><♂>
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Jerris Robert Hedges

UNIVERSITY OF HAWAII AT MANOA, HONOLULU, HI

Exploratory lead · 18/100
Active award
Team-scale grant
$123,715
FY 2025

Project Title

Ola HAWAII

Grant Number:

3U54MD007601-39S1

Activity Code:

U54

Mechanism:

Research Centers

Agency:

NIH

Start Date:

9/23/1997

End Date:

5/31/2027

Project Abstract

PROJECT SUMMARY/ABSTRACT With continued support from the National Institute on Minority Health and Health Disparities (NIMHD) through the RCMI U54 RFA-MD-22-002, the goal of Ola HAWAII is to improve minority health and reduce health disparities for those communities in Hawaii which suffer disproport...

Research Terms

<Acceleration><Address><Area><Basic Research><Basic Science><Behavioral Research><Biomedical Research><Burn injury><Burns><COVID-19><CV-19><Cancers><Cardiovascular Diseases><Climacteric><Clinical Research><Clinical Study><Collaborations><Communities><Community Participation><Core Facility><Coronavirus Infectious Disease 2019><Decrease health disparities><Diabetes Mellitus><Disparities><Disparity><Ethnic Group><Ethnic People><Ethnic Population><Ethnic individual><Ethnicity People><Ethnicity Population><Evaluation><Faculty><Filipino><Funding><Goals><Hawaii><Hawaiian><Health><Health Disparities Research><Health Policy><Health disparities related research><Health disparity mitigation><Health disparity reduction><Inequality><Institution><Investigators><Island><Lead><Letters><Lower health disparities><Malignant Neoplasms><Malignant Tumor><Measures><Mentors><Minority-Serving Institution><Mitigate health disparities><NCMHD><NIMHD><Names><National Center on Minority Health and Health Disparities><National Institute of Minority Health and Health Disparities><National Institute on Minority Health and Health Disparities><Native Hawaiian and Other Pacific Islander><Native Hawaiian and Pacific Islander><Native Hawaiian or Other Pacific Islander><Native Hawaiian or Pacific Islander><Outcome><Outcomes Research><P50 Mechanism><P50 Program><Pb element><Pilot Projects><Policies><Policy Developments><Postdoc><Postdoctoral Fellow><Principal Investigator><Process><Productivity><Public Health><Racial Group><Reduce health disparities><Research><Research Associate><Research Personnel><Research Resources><Researchers><Resource Allocation><Resource Sharing><Resources><Services><Specialized Center><Translations><Trust><Underserved Population><Universities><Work><access to health care><accessibility of health care><accessibility to health care><aspirate><base><bases><burned><cardiovascular disorder><collaboration with communities><community collaboration><community-based collaboration><coronavirus disease 2019><coronavirus disease-19><coronavirus infectious disease-19><diabetes><disparity in health><ethnic subgroup><ethnicity group><healing><health care access><health care availability><health care policy><health care service access><health care service availability><health disparities science><health disparity><health equity><heavy metal Pb><heavy metal lead><improve minority health><improved><improvement of minority health><innovate><innovation><innovative><institutional capacity><life change><malignancy><medical college><medical schools><medically under served><medically underserved><minority health><minority health disparity><minority institution><name><named><naming><neoplasm/cancer><new approaches><novel approaches><novel strategies><novel strategy><pilot study><post-doc><post-doctoral><post-doctoral trainee><programs><racial population><racial subgroup><recruit><research associates><research facility><school of medicine><success><translation><under served community><under served group><under served individual><under served people><under served population><underserved community><underserved group><underserved individual><underserved people>
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Noreen Mokuau

UNIVERSITY OF HAWAII AT MANOA, HONOLULU, HI

Exploratory lead · 18/100
Active award
Team-scale grant
$123,715
FY 2025

Project Title

Ola HAWAII

Grant Number:

3U54MD007601-39S1

Activity Code:

U54

Mechanism:

Research Centers

Agency:

NIH

Start Date:

9/23/1997

End Date:

5/31/2027

Project Abstract

PROJECT SUMMARY/ABSTRACT With continued support from the National Institute on Minority Health and Health Disparities (NIMHD) through the RCMI U54 RFA-MD-22-002, the goal of Ola HAWAII is to improve minority health and reduce health disparities for those communities in Hawaii which suffer disproport...

Research Terms

<Acceleration><Address><Area><Basic Research><Basic Science><Behavioral Research><Biomedical Research><Burn injury><Burns><COVID-19><CV-19><Cancers><Cardiovascular Diseases><Climacteric><Clinical Research><Clinical Study><Collaborations><Communities><Community Participation><Core Facility><Coronavirus Infectious Disease 2019><Decrease health disparities><Diabetes Mellitus><Disparities><Disparity><Ethnic Group><Ethnic People><Ethnic Population><Ethnic individual><Ethnicity People><Ethnicity Population><Evaluation><Faculty><Filipino><Funding><Goals><Hawaii><Hawaiian><Health><Health Disparities Research><Health Policy><Health disparities related research><Health disparity mitigation><Health disparity reduction><Inequality><Institution><Investigators><Island><Lead><Letters><Lower health disparities><Malignant Neoplasms><Malignant Tumor><Measures><Mentors><Minority-Serving Institution><Mitigate health disparities><NCMHD><NIMHD><Names><National Center on Minority Health and Health Disparities><National Institute of Minority Health and Health Disparities><National Institute on Minority Health and Health Disparities><Native Hawaiian and Other Pacific Islander><Native Hawaiian and Pacific Islander><Native Hawaiian or Other Pacific Islander><Native Hawaiian or Pacific Islander><Outcome><Outcomes Research><P50 Mechanism><P50 Program><Pb element><Pilot Projects><Policies><Policy Developments><Postdoc><Postdoctoral Fellow><Principal Investigator><Process><Productivity><Public Health><Racial Group><Reduce health disparities><Research><Research Associate><Research Personnel><Research Resources><Researchers><Resource Allocation><Resource Sharing><Resources><Services><Specialized Center><Translations><Trust><Underserved Population><Universities><Work><access to health care><accessibility of health care><accessibility to health care><aspirate><base><bases><burned><cardiovascular disorder><collaboration with communities><community collaboration><community-based collaboration><coronavirus disease 2019><coronavirus disease-19><coronavirus infectious disease-19><diabetes><disparity in health><ethnic subgroup><ethnicity group><healing><health care access><health care availability><health care policy><health care service access><health care service availability><health disparities science><health disparity><health equity><heavy metal Pb><heavy metal lead><improve minority health><improved><improvement of minority health><innovate><innovation><innovative><institutional capacity><life change><malignancy><medical college><medical schools><medically under served><medically underserved><minority health><minority health disparity><minority institution><name><named><naming><neoplasm/cancer><new approaches><novel approaches><novel strategies><novel strategy><pilot study><post-doc><post-doctoral><post-doctoral trainee><programs><racial population><racial subgroup><recruit><research associates><research facility><school of medicine><success><translation><under served community><under served group><under served individual><under served people><under served population><underserved community><underserved group><underserved individual><underserved people>
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Cecile Delille Lahiri

EMORY UNIVERSITY, ATLANTA, GA

Exploratory lead · 18/100
Active award
Career award
$123,104
FY 2025

Project Title

Mentoring in Sex and Gender-informed Multidisciplinary Research on Cardiometabolic Comorbidities in Persons with HIV

Grant Number:

1K24HL176324-01A1

Activity Code:

K24

Mechanism:

Other Research-Related

Agency:

NIH

Start Date:

1/1/2025

End Date:

12/31/2029

Project Abstract

PROJECT SUMMARY/ABSTRACT Cardiovascular disease (CVD) accounts for significant morbidity and mortality among persons living with HIV (PWH) on antiretroviral therapy (ART). Compared to HIV-seronegative individuals, PWH experience higher risk of acute myocardial infarction, sudden cardiac death, and ...

Research Terms

<AIDS><AIDS Virus><Accounting><Acquired Immune Deficiency><Acquired Immune Deficiency Syndrome><Acquired Immune Deficiency Syndrome Virus><Acquired Immunodeficiency Syndrome><Acquired Immunodeficiency Syndrome Virus><Acute myocardial infarct><Acute myocardial infarction><Advanced Development><Aging><Amino Acids><Area><Automobile Driving><Autoregulation><Biopsy><Blood><Blood Plasma><Blood Reticuloendothelial System><Body Tissues><CD4 Cells><CD4 Positive T Lymphocytes><CD4 T cells><CD4 helper T cell><CD4 lymphocyte><CD4+ T-Lymphocyte><CD4-Positive Lymphocytes><COBRE><Carbohydrates><Cardiometabolic Disease><Cardiometabolic Disorder><Cardiovascular Diseases><Carotid Atheroscleroses><Carotid Atherosclerotic Disease><Cell Body><Cells><Center of Biomedical Research Excellence><Centers of Research Excellence><Cessation of life><Chronic><Clinical><Clinical Research><Clinical Study><Cohort Studies><Collaborations><Communicable Diseases><Concurrent Studies><DNA><DNA Integration><Data><Death><Deoxyribonucleic Acid><Development><Differences between sexes><Differs between sexes><Dilatation><Dilatation - action><Disease><Disorder><Dysfunction><Enrollment><Ensure><Estrogen deficiency><Event><Functional disorder><Funding><Gender><Goals><Groups at risk><HIV><HIV Infections><HIV infected men><HIV positive men><HIV+ men><HTLV-III Infections><HTLV-III-LAV Infections><High Risk Woman><Homeostasis><Human Immunodeficiency Viruses><Human T-Lymphotropic Virus Type III Infections><Immune><Immune Cell Activation><Immunes><Immunology><Incidence><Individual><Infectious Diseases><Infectious Disorder><Inflammation><Interdisciplinary Research><Interdisciplinary Study><K24 Award><Knowledge><LAV-HTLV-III><Leadership><Life Expectancy><Link><Lipids><Long-term cohort><Longitudinal cohort><Lymphadenopathy-Associated Virus><MR Imaging><MR Tomography><MRI><MRIs><Magnetic Resonance Imaging><Males living with HIV><Measurement><Mediating><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Medicine><Men with HIV><Mentors><Mentorship><Metabolic Pathway><Methodology><Methods><Mid-Career Clinical Scientist Award (K24)><Morbidity><Morbidity - disease rate><Multidisciplinary Collaboration><Multidisciplinary Research><NIH><NMR Imaging><NMR Tomography><National Institutes of Health><Network Analysis><Non-Polyadenylated RNA><Nuclear Magnetic Resonance Imaging><Obesity><Outcome><P50 Mechanism><P50 Program><PBMC><Pathologic><Pathway Analysis><Pathway interactions><People at risk><Perimenopausal><Perimenopause><Peripheral><Peripheral Blood Mononuclear Cell><Persons><Persons at risk><Phosphatides><Phospholipids><Physiological Homeostasis><Physiopathology><Plasma><Plasma Serum><Play><Population><Populations at Risk><Post-Menopause><Post-menopausal Period><Postmenopausal Period><Postmenopause><Prevalence><Preventative intervention><Preventative strategy><Prevention><Prevention strategy><Preventive strategy><Program Development><RNA><RNA Gene Products><Rectum><Relative Risks><Research><Research Infrastructure><Research Specimen><Resolution><Reticuloendothelial System, Serum, Plasma><Ribonucleic Acid><Risk><Role><Sampling><Science><Scientist><Severities><Sex Differences><Sexual differences><Source><Specialized Center><Specimen><Structure><T-Cells><T-Lymphocyte><T4 Cells><T4 Lymphocytes><Time><Tissues><Training><United States><United States National Institutes of Health><Vascular Diseases><Vascular Disorder><Viral><Virus-HIV><Visualization><Woman><Work><Zeugmatography><adiposity><after menopause><aged><aminoacid><antiretroviral therapy><antiretroviral treatment><arterial tonometry><associate faculty><associate professor><at-risk females><at-risk women><biomarker identification><blood vessel disorder><cardiometabolic><cardiometabolic risk><cardiometabolism><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder risk><cardiovascular risk><cardiovascular risk factor><career><career development><co-morbid><co-morbidity><comorbidity><comparing females and males><comparing women and men><corpulence><data integration><data tools><deficiency in estrogen><developmental><driving><early onset><enroll><experience><females at high risk><females compared to males><females compared with males><females versus males><females vs. males><following menopause><high risk><high risk females><high risk group><high risk individual><high risk men><high risk people><high risk population><identification of biomarkers><identification of new biomarkers><immune activation><improved><insight><intervention for prevention><lipidome><lipidomics><man living with HIV><marker identification><men at high risk><men diagnosed with HIV><men infected with HIV><men living with HIV><menopause transition><metabolism measurement><metabolome><metabolomics><metabonome><metabonomics><mid-career faculty><midcareer faculty><mortality><multidisciplinary><multiomics><multiple omics><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation><next generation therapeutics><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><panomics><past menopause><pathophysiology><pathway><patient centered><patient oriented><patient oriented research><patient oriented study><peri-menopausal><peri-menopause><post-menopausal><postmenopausal><postmenopausal status><prevention intervention><preventional intervention strategy><preventive intervention><programs><progression risk><research study><resolutions><sex><sex based differences><sex-dependent differences><sex-related differences><sex-specific differences><skills><social role><sudden cardiac death><systemic inflammation><systemic inflammatory response><thymus derived lymphocyte><training opportunity><transition to menopause><transitional menopause><vascular dysfunction><vasculopathy><virology><women at high risk><women compared to men><women compared with men><women versus men><women vs. men>
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Lauren E Wagner

UNIVERSITY OF CALIFORNIA LOS ANGELES, LOS ANGELES, CA

Exploratory lead · 18/100
Training-friendly
$15,339
FY 2025

Project Title

Early Neurodevelopmental Trajectories of Typical and Atypical Language Acquisition

Grant Number:

5F31HD108987-03

Activity Code:

F31

Mechanism:

Training, Individual

Agency:

NIH

Start Date:

1/19/2023

End Date:

3/21/2025

Why this may be worth a closer look

  • • Activity code is useful for trainees, fellows, or mentored roles.

Project Abstract

Project Summary/Abstract Developmental language impairments are common in the general population, affecting approximately 1 in 10 children. Despite this prevalence, little is known about the etiology of language difficulties observed in conditions such as Autism Spectrum Disorder (ASD). Earlier ther...

Research Terms

<0-11 years old><0-4 weeks old><ASD><Affect><Age Months><Anisotropy><Area><Autism><Autistic Disorder><Behavioral><Birth><Brain><Brain Nervous System><Brain region><Business-Friendly Atmosphere><Causality><Cerebellum><Cerebrum><Child><Child Youth><Childhood><Children (0-21)><Communication><Contralateral><Corpus Callosum><Corpus Callosums><Coupling><DWI (diffusion weighted imaging)><DWI-MRI><Data><Development><Developmental Disorder Speech or Language><Developmental Language Disorders><Diffusion MRI><Diffusion Magnetic Resonance Imaging><Diffusion Weighted MRI><Diffusion weighted imaging><Diffusion-weighted Magnetic Resonance Imaging><Disease><Disorder><Early Diagnosis><Early Infantile Autism><Early Intervention><Early identification><Educational process of instructing><Emotional><Employment><Encephalon><Environment><Etiology><Exhibits><Fellowship><Foundations><Functional MRI><Functional Magnetic Resonance Imaging><Funding><Future><General Population><General Public><High Prevalence><Image><Individual Differences><Infant><Infantile Autism><Information Dissemination><Infrastructure><Japanese><Kanner's Syndrome><Language><Language Delays><Language Development><Language Development Disorders><Left><Life><Literature><Longitudinal Studies><MR Imaging><MR Tomography><MRI><MRIs><Magnetic Resonance Imaging><Measures><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Methods><NICHD><NIH><NMR Imaging><NMR Tomography><NRSA><National Institute of Child Health and Human Development><National Institutes of Health><National Research Service Awards><Neural Development><Neurodevelopmental Disorder><Neurological Development Disorder><Neurosciences><Newborn Infant><Newborns><Nuclear Magnetic Resonance Imaging><Outcome><Parturition><Pattern><Population><Prevalence><Probabilistic Models><Probability Models><Public Health><Research><Research Resources><Research Training><Resources><Rest><Risk><Role><Sample Size><Sign Language><Sleep><Social outcome><Speech><Statistical Models><Stimulus><Stream><Structure><Teaching><Therapeutic Intervention><Time><Toddler><Training><United States National Institutes of Health><Zeugmatography><acquiring language skills><adult with ASD><adult with autism><adult with autism spectrum disorder><adults on the autism spectrum><adults on the spectrum><adverse consequence><adverse outcome><autism spectral disorder><autism spectrum disorder><autistic adult><autistic spectrum disorder><business-friendly environment><career><causation><cerebral><collaborative atmosphere><collaborative environment><connectome><dMRI><developmental><diffusion tensor imaging><disease causation><dissemination of results><early biomarkers><early detection><early detection biomarkers><early detection markers><effective intervention><experience><fMRI><graduate student><high risk><imaging><imaging study><improved><indexing><infancy><infantile><interactive atmosphere><interactive environment><interdisciplinary atmosphere><interdisciplinary environment><intervention therapy><kids><language ability><language acquisition><language impairment><language learning><language outcome><language processing><language skills><later in life><later life><long-term study><longitudinal design><longitudinal experimental design><longitudinal outcome studies><longitudinal research design><longitudinal study design><neural><neural imaging><neural network><neuro-imaging><neurodevelopment><neurodevelopmental disease><neuroimaging><neurological imaging><newborn child><newborn children><non-Native><nonnative><pediatric><peer-group atmosphere><peer-group environment><postnatal><response><social role><speech processing><statistical linear mixed models><statistical linear models><substantia alba><support network><symptomatology><tractography><white matter><youngster>
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Wayne A. Marasco

DANA-FARBER CANCER INST, BOSTON, MA

Exploratory lead · 16/100
Active award
$208,220
FY 2026

Project Title

In vivo testing of an agonistic anti-GITR mAb that induces cell surface clustering to augment signal transduction and a 2nd Gen bispecific anti-GITR/PD1 Ab derivative for improved anti-tumor activity

Grant Number:

5R21CA286345-02

Activity Code:

R21

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

2/1/2024

End Date:

1/31/2027

Project Abstract

Project Summary The durability of clinical responses to immune checkpoint inhibitors targeting PD1 has generated tremendous interest in immunotherapy of cancers. However, not all patients demonstrate a complete or durable response and thus, there is a need to develop additional therapeutic antibodie...

Research Terms

<Address><Antibodies><Antibody Therapy><Antitumor Response><Assay><B7-H1><Bi-specific antibodies><Bifunctional Antibodies><Binding><Bioassay><Biological Assay><Bispecific Antibodies><Bp50><C1 q><C1q><CD152><CD152 Antigen><CD152 Gene><CD274><CD40><CDW40><CTLA 4><CTLA-4 Gene><CTLA4><CTLA4 gene><CTLA4-TM><Cachectin Receptors><Cancers><Cell Body><Cell Communication and Signaling><Cell Mediated Immunology><Cell Signaling><Cell surface><Cell-Mediated Immunity><Cells><Cellular Immunity><Checkpoint inhibitor><Clear cell renal cell carcinoma><Clinical><Clinical Treatment Moab><Combined Modality Therapy><Complement><Complement 1q><Complement C1q><Complement Proteins><Complement-Dependent Cytotoxicity><Cytotoxic T-Lymphocyte Protein 4><Cytotoxic T-Lymphocyte-Associated Antigen 4><Cytotoxic T-Lymphocyte-Associated Protein 4><Cytotoxic T-Lymphocyte-Associated Serine Esterase-4><Cytotoxic cell><DNA mutation><Deposit><Deposition><Development><Engineering><Evaluation><Fc domain><Gases><Genetic Change><Genetic defect><Genetic mutation><Grawitz Tumor><Human><Hypernephroid Carcinoma><Hypernephroma><IgG1><Immune><Immune checkpoint inhibitor><Immune mediated therapy><Immune response><Immune system><Immunes><Immunohistochemistry><Immunohistochemistry Cell/Tissue><Immunohistochemistry Staining Method><Immunologically Directed Therapy><Immunotherapy><In Vitro><In vivo analysis><Intracellular Communication and Signaling><K lymphocyte><Ligands><Luciferase Immunologic><Luciferases><MGC9013><Malignant Neoplasms><Malignant Tumor><Mediating><Mice><Mice Mammals><Modeling><Modern Man><Molecular Interaction><Monoclonal Antibodies><Multimodal Therapy><Multimodal Treatment><Murine><Mus><Mutation><NK Cells><Natural Killer Cells><Nature><Nephroid Carcinoma><Orthoptics><PD 1><PD-1><PD-1 antibody><PD-1 antibody therapy><PD-1 therapy><PD-1/PD-L1><PD-1/PDL1><PD-L1><PD-L1 antibody><PD1><PD1 antibody><PD1 antibody therapy><PD1 based treatment><PD1-PD-L1><PD1/PD-L1><PD1/PDL1><PDL-1><Pathway interactions><Patients><Pleoptic><Principal Investigator><Programmed Cell Death 1 Ligand 1><Programmed Death Ligand 1><Receptor Protein><Receptor Signaling><Regulatory T-Lymphocyte><Renal Adenocarcinoma><Renal Cell Adenocarcinoma><Renal Cell Cancer><Renal Cell Carcinoma><Role><Series><Signal Transduction><Signal Transduction Systems><Signaling><Structure><Surface><T-Cell Activation><TNF Receptor Family Protein><TNF Receptor Superfamily><TNF Receptors><TNFR><TNFRSF5><TNFRSF5 gene><Techniques><Technology><Therapeutic><Therapeutic Uses><Therapeutic antibodies><Treatment Efficacy><Treg><Tumor Cell><Tumor Immunity><Tumor Necrosis Factor Receptor><Tumor Necrosis Factor Receptor Family><Tumor Necrosis Factor Receptor Superfamily><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><Variant><Variation><Writing><aPD-1><aPD-1 therapy><aPD-1 treatment><aPD-L1><aPD-L1 antibodies><aPD1><aPD1 therapy><aPD1 treatment><activate T cells><advanced analytics><anti programmed cell death 1><anti programmed cell death ligand 1><anti programmed cell death protein ligand 1><anti-PD-(L)1><anti-PD-1><anti-PD-1 Ab><anti-PD-1 antibodies><anti-PD-1 monoclonal antibodies><anti-PD-1 therapy><anti-PD-1 treatment><anti-PD-L1><anti-PD-L1 antibodies><anti-PD-L1 monoclonal antibodies><anti-PD1><anti-PD1 Ab><anti-PD1 antibodies><anti-PD1 monoclonal antibodies><anti-PD1 therapy><anti-PD1 treatment><anti-PDL-1><anti-PDL1><anti-PDL1 antibodies><anti-cancer immunotherapy><anti-programmed cell death 1 therapy><anti-programmed cell death protein 1><anti-programmed cell death protein 1 antibodies><anti-programmed cell death protein 1 therapy><anti-programmed death-1 antibody><anti-tumor immunity><anti-tumor response><antiPD-1><antiPD-L1><antibody based therapies><antibody engineering><antibody treatment><antibody-based therapeutics><antibody-based treatment><anticancer immunotherapy><antitumor immunity><biological signal transduction><bsAb><cancer immunity><cancer immunotherapy><cancer microenvironment><ccRCC><check point blockade><checkpoint blockade><combination therapy><combined modality treatment><combined treatment><comparable efficacy><comparative efficacy><compare efficacy><complement-mediated cytotoxicity><complementation><cytotoxic><cytotoxic T-lymphocyte antigen 4><developmental><exhaust><exhaustion><genome mutation><host response><humanized mice><humanized mouse><immune check point blockade><immune check point inhibitor><immune checkpoint blockade><immune system response><immune therapeutic approach><immune therapeutic interventions><immune therapeutic regimens><immune therapeutic strategy><immune therapy><immune-based cancer therapies><immune-based therapies><immune-based treatments><immuno therapy><immunoresponse><immunotherapy for cancer><immunotherapy of cancer><improved><in vitro testing><in vivo><in vivo evaluation><in vivo testing><insight><interest><intervention efficacy><kidney adenocarcinoma><mAbs><malignancy><member><monoclonal Abs><monomer><mouse model><multi-modal therapy><multi-modal treatment><murine model><mutant><neoplasm/cancer><neoplastic cell><novel><p50><pathway><programmed cell death 1><programmed cell death ligand 1><programmed cell death protein 1><programmed cell death protein 1 therapy><programmed cell death protein ligand 1><programmed death 1><programs><protein death-ligand 1><receptor><regulatory T-cells><response><restoration><scRNA sequencing><scRNA-seq><single cell RNA-seq><single cell RNAseq><single cell expression profiling><single cell transcriptomic profiling><single-cell RNA sequencing><sle2><social role><systemic lupus erythematosus susceptibility 2><therapeutic efficacy><therapy efficacy><tumor><tumor microenvironment><αPD-1><αPD-L1><αPD-L1 antibodies><αPD1><αPDL1>
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Cari Renee Levy

VA EASTERN COLORADO HEALTH CARE SYSTEM, Aurora, CO

Exploratory lead · 16/100
Active award
$0
FY 2026

Project Title

Palliative Care as a Parkinson's Disease Standard of Care

Grant Number:

5I01HX003611-03

Activity Code:

I01

Mechanism:

Non-SBIR/STTR

Agency:

VA

Start Date:

10/1/2023

End Date:

9/30/2027

Project Abstract

Background: Parkinson’s disease (PD) is the second most common neurodegenerative condition among individuals over the age of 60 years and Veterans are at increased risk of PD due to traumatic head injuries and exposure to herbicides. PD causes both motor symptoms such as tremor but also distressing ...

Research Terms

<Address><Advance Care Planning><Advance Health Care Planning><Affect><Age><Amentia><American><Application Context><Care giver support><Caregiver support><Caring><Cause of Death><Clinical><Complex><Consultations><Craniocerebral Injuries><Craniocerebral Trauma><Data><Data Analyses><Data Analysis><Dementia><Diagnosis><Disease Management><Disorder Management><Distress><Education><Educational aspects><Emotional><Evaluation><Exposure to><Family><Feedback><Generalized Growth><Goals><Growth><Head Injuries><Head Trauma><Herbicides><Individual><Influentials><Intervention><Interview><Investments><Lead><Leadership><Link><Medical center><Mental Depression><Methodology><Modeling><Nerve Degeneration><Neurologist><Neurology><Neuron Degeneration><Nursing Homes><Out-patients><Outcome><Outpatients><P50 Mechanism><P50 Program><PRISM framework><PRISM model><Pain><Painful><Palliative Care><Palliative Therapy><Palliative Treatment><Paralysis Agitans><Parkinson><Parkinson Disease><Patient Care><Patient Care Delivery><Patients><Pb element><Position><Positioning Attribute><Practical Robust Implementation and Sustainability Model><Pragmatic, Robust Implementation and Sustainability Model><Primary Parkinsonism><Provider><Psychoses><Psychosocial Assessment and Care><Psychosocial Influences><Psychosocial Issues><QOL><Quality of life><RE-AIM><Randomized><Reach, Effectiveness, Adoption, Implementation, and Maintenance><Reporting><Research><Research Resources><Resources><Risk><Services><Site><Specialist><Specialized Center><Specialty><Spirituality><Structure><Symptoms><Tissue Growth><Training><Travel><Tremor><United States Department of Veterans Affairs><United States Veterans Administration><Veterans><Veterans Administration><Veterans Affairs><ages><associated symptom><barriers to implementation><budget impact><care for patients><care giver stress><care of patients><care partner><care preference><caregiver distress><caregiver stress><caregiving partner><caring for patients><clinical center><co-morbid symptom><co-occuring symptom><comfort care><comorbid symptom><concurrent symptom><consultation><contextual factors><cooccuring symptom><coping><data interpretation><depression><disability><experience><facilitators to implementation><future implementation><heavy metal Pb><heavy metal lead><implementation barriers><implementation challenges><implementation efforts><implementation facilitators><implementation framework><implementation outcomes><implementation research framework><implementation science framework><implementation strategy><improved><innovate><innovation><innovative><inpatient care><inpatient service><interest><intervention delivery><intervention refinement><manage symptom><medical specialties><motor symptom><neural degeneration><neurodegeneration><neurodegenerative><neurological degeneration><neuronal degeneration><non-motor symptom><nonmotor symptom><nursing home><ontogeny><palliative intervention><primary outcome><programs><psychosocial assessment><psychosocial care><psychosocial studies><psychosocial support><randomisation><randomization><randomly assigned><reach, efficacy, adoption, implementation, and maintenance><recruit><scale up><standard of care><strategies for implementation><stress among caregiver><stress in caregiver><stress on caregiver><success><symptom association><symptom comorbidity><symptom management><theories><tool>
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MARIETTA Y. LEE

NEW YORK MEDICAL COLLEGE, VALHALLA, NY

Exploratory lead · 10/100
Active award
$247,500
FY 2025

Project Title

The role of DNA Polymerase Delta 4 in Lung Carcinogenesis Induced by Genotoxic Carcinogens

Grant Number:

5R21ES036369-02

Activity Code:

R21

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

6/18/2024

End Date:

5/31/2027

Project Abstract

ABSTRACT Lung cancer is the leading cause of cancer-related death in the world. Exposures to airborne carcinogens contribute significantly to lung carcinogenesis. Genotoxic carcinogens, which can come from environmental and/or occupational settings, are the most important causes of lung malignancy ...

Research Terms

<3,4-Benzopyrene><3,4-Benzpyrene><Agar><Anaplastic T-Lymphocyte with Horseshoe-Shaped Nucleus><Anaplastic T-Lymphocyte with Kidney-Shaped Nucleus><Animals><Assay><Athymic Mice><Athymic Nude Mouse><Benzo(a)pyrene><Bioassay><Biological Assay><Bp50><CD40><CDW40><Cancer Cause><Cancer Causing Agents><Cancer Etiology><Cancer Induction><Cancer Prevention Intervention><Cancers><Carcinogen-DNA Adducts><Carcinogens><Catalytic Core><Catalytic Domain><Catalytic Region><Catalytic Site><Catalytic Subunit><Cell Body><Cell Cycle><Cell Division Cycle><Cell Function><Cell Line><Cell Physiology><Cell Process><Cell model><CellLine><Cells><Cellular Expansion><Cellular Function><Cellular Growth><Cellular Physiology><Cellular Process><Cellular model><Cessation of life><Chromosomal, Gene, or Protein Abnormality><Chronic><Cr(VI)><Cytogenetic or Molecular Genetic Abnormality><DNA Adducts><DNA Damage><DNA Damage Repair><DNA Double Strand Break><DNA Injury><DNA Polymerase III><DNA Polymerase delta><DNA Repair><DNA Replication><DNA Synthesis><DNA biosynthesis><DNA mutation><DNA-Dependent DNA Polymerase III><Death><Defect><Dose><E3 Ligase><E3 Ubiquitin Ligase><Elements><Enzyme Gene><Enzymes><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Epithelial Cells><Ethyl Carbamate><Ethyl Urethan><Event><Excision Repair><Exposure to><Future><Genes><Genetic Abnormality><Genetic Change><Genetic defect><Genetic mutation><Genomic DNA><Goals><Hallmark Cell><Human><KO mice><Ketones><Knock-out><Knock-out Mice><Knockout><Knockout Mice><Laboratories><Lung><Lung Neoplasms><Lung Respiratory System><Lung Tumor><MGC9013><Malignant><Malignant - descriptor><Malignant Neoplasms><Malignant Tumor><Malignant Tumor of the Lung><Malignant neoplasm of lung><Mediator><Mice><Mice Mammals><Modeling><Modern Man><Molecular><Molecular Abnormality><Murine><Mus><Mutation><Neoplastic Cell Transformation><Nicotine><Nitrosamines><Nude Mice><Null Mouse><Occupational><Oncogenesis><Oncogens><Pathologic><Pathway interactions><Play><Pol III><Process><Pulmonary Cancer><Pulmonary Neoplasms><Pulmonary malignant Neoplasm><Regulation><Research><Role><Route><S Period><S phase><Strains Cell Lines><Subcellular Process><Synthesis Period><Synthesis Phase><System><TNFRSF5><TNFRSF5 gene><Testing><Therapeutic><Therapeutic Intervention><Time><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><Tumor Xenograft Assay><Ubiquitin Ligase Component Gene><Ubiquitin Ligase Gene><Ubiquitin Protein Ligase><Ubiquitin-Protein Ligase Complexes><Ubiquitin-Protein Ligase E3><Unscheduled DNA Synthesis><Urethane><Validation><Wild Type Mouse><Work><Xenograft Antitumor Assays><Xenograft Model Antitumor Assays><Yeasts><airborne carcinogen><carcinogenesis><carcinogenicity><cell growth><cell transformation><chromium hexavalent ion><chromium(VI)><cultured cell line><driving force><epigenetic regulation><epigenetically><ethyl ester carbamic acid><experience><gDNA><genome mutation><genotoxicity><hexavalent chromium><homologous recombination><in vivo><in vivo Model><intervention therapy><lung cancer><lung cancer cell><lung cancer prevention><lung carcinogenesis><lung tumorigenesis><malignancy><molecular aberrations><mouse model><murine model><neoplasm/cancer><neoplastic transformation><novel><oncogenic agent><p50><pathway><repair><repaired><response><social role><subcutaneous><subdermal><tool><transformed cells><tumor><tumor DNA><tumor cell DNA><tumor-specific DNA><tumorigenesis><tumorigenesis in the lung><ubiquitin ligase><ubiquitin-protein ligase><validations><wildtype mouse>
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DAZHONG XU

NEW YORK MEDICAL COLLEGE, VALHALLA, NY

Exploratory lead · 10/100
Active award
$247,500
FY 2025

Project Title

The role of DNA Polymerase Delta 4 in Lung Carcinogenesis Induced by Genotoxic Carcinogens

Grant Number:

5R21ES036369-02

Activity Code:

R21

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

6/18/2024

End Date:

5/31/2027

Project Abstract

ABSTRACT Lung cancer is the leading cause of cancer-related death in the world. Exposures to airborne carcinogens contribute significantly to lung carcinogenesis. Genotoxic carcinogens, which can come from environmental and/or occupational settings, are the most important causes of lung malignancy ...

Research Terms

<3,4-Benzopyrene><3,4-Benzpyrene><Agar><Anaplastic T-Lymphocyte with Horseshoe-Shaped Nucleus><Anaplastic T-Lymphocyte with Kidney-Shaped Nucleus><Animals><Assay><Athymic Mice><Athymic Nude Mouse><Benzo(a)pyrene><Bioassay><Biological Assay><Bp50><CD40><CDW40><Cancer Cause><Cancer Causing Agents><Cancer Etiology><Cancer Induction><Cancer Prevention Intervention><Cancers><Carcinogen-DNA Adducts><Carcinogens><Catalytic Core><Catalytic Domain><Catalytic Region><Catalytic Site><Catalytic Subunit><Cell Body><Cell Cycle><Cell Division Cycle><Cell Function><Cell Line><Cell Physiology><Cell Process><Cell model><CellLine><Cells><Cellular Expansion><Cellular Function><Cellular Growth><Cellular Physiology><Cellular Process><Cellular model><Cessation of life><Chromosomal, Gene, or Protein Abnormality><Chronic><Cr(VI)><Cytogenetic or Molecular Genetic Abnormality><DNA Adducts><DNA Damage><DNA Damage Repair><DNA Double Strand Break><DNA Injury><DNA Polymerase III><DNA Polymerase delta><DNA Repair><DNA Replication><DNA Synthesis><DNA biosynthesis><DNA mutation><DNA-Dependent DNA Polymerase III><Death><Defect><Dose><E3 Ligase><E3 Ubiquitin Ligase><Elements><Enzyme Gene><Enzymes><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Epithelial Cells><Ethyl Carbamate><Ethyl Urethan><Event><Excision Repair><Exposure to><Future><Genes><Genetic Abnormality><Genetic Change><Genetic defect><Genetic mutation><Genomic DNA><Goals><Hallmark Cell><Human><KO mice><Ketones><Knock-out><Knock-out Mice><Knockout><Knockout Mice><Laboratories><Lung><Lung Neoplasms><Lung Respiratory System><Lung Tumor><MGC9013><Malignant><Malignant - descriptor><Malignant Neoplasms><Malignant Tumor><Malignant Tumor of the Lung><Malignant neoplasm of lung><Mediator><Mice><Mice Mammals><Modeling><Modern Man><Molecular><Molecular Abnormality><Murine><Mus><Mutation><Neoplastic Cell Transformation><Nicotine><Nitrosamines><Nude Mice><Null Mouse><Occupational><Oncogenesis><Oncogens><Pathologic><Pathway interactions><Play><Pol III><Process><Pulmonary Cancer><Pulmonary Neoplasms><Pulmonary malignant Neoplasm><Regulation><Research><Role><Route><S Period><S phase><Strains Cell Lines><Subcellular Process><Synthesis Period><Synthesis Phase><System><TNFRSF5><TNFRSF5 gene><Testing><Therapeutic><Therapeutic Intervention><Time><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><Tumor Xenograft Assay><Ubiquitin Ligase Component Gene><Ubiquitin Ligase Gene><Ubiquitin Protein Ligase><Ubiquitin-Protein Ligase Complexes><Ubiquitin-Protein Ligase E3><Unscheduled DNA Synthesis><Urethane><Validation><Wild Type Mouse><Work><Xenograft Antitumor Assays><Xenograft Model Antitumor Assays><Yeasts><airborne carcinogen><carcinogenesis><carcinogenicity><cell growth><cell transformation><chromium hexavalent ion><chromium(VI)><cultured cell line><driving force><epigenetic regulation><epigenetically><ethyl ester carbamic acid><experience><gDNA><genome mutation><genotoxicity><hexavalent chromium><homologous recombination><in vivo><in vivo Model><intervention therapy><lung cancer><lung cancer cell><lung cancer prevention><lung carcinogenesis><lung tumorigenesis><malignancy><molecular aberrations><mouse model><murine model><neoplasm/cancer><neoplastic transformation><novel><oncogenic agent><p50><pathway><repair><repaired><response><social role><subcutaneous><subdermal><tool><transformed cells><tumor><tumor DNA><tumor cell DNA><tumor-specific DNA><tumorigenesis><tumorigenesis in the lung><ubiquitin ligase><ubiquitin-protein ligase><validations><wildtype mouse>
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Ouathek Ouerfelli

SLOAN-KETTERING INST CAN RESEARCH, NEW YORK, NY

Exploratory lead · 10/100
Active award
$247,416
FY 2025

Project Title

Organic Synthesis at the Service of Biology and Medicine

Grant Number:

5R50CA243895-07

Activity Code:

R50

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/17/2019

End Date:

8/31/2029

Project Abstract

Abstract: Dr. Ouathek Ouerfelli directs the Organic Synthesis Core Facility (OSCF) at Memorial Sloan Kettering Cancer Center (MSK) since 2004. He is committed to continue to provide chemistry services for the MSK research community and the development of new tools and therapeutic agents for cancer d...

Research Terms

<Agreement><Alopecia><Baldness><Binding><Biology><Business-Friendly Atmosphere><Cancer Detection><Cancers><Center for Cancer Research><Chemicals><Chemistry><Collaborations><Communities><Core Facility><Detection><Development><Disease><Disorder><Drugs><FDA approved><Funding><Human Resources><Investigators><Knowledge><Leadership><MSKCC><Malignant Neoplasms><Malignant Tumor><Manpower><Medication><Medicinal Chemistry><Medicine><Memorial Sloan-Kettering Cancer Center><Molecular Interaction><NCI Center for Cancer Research><Organic Synthesis><Pharmaceutic Chemistry><Pharmaceutical Chemistry><Pharmaceutical Preparations><Prevention><Research><Research Personnel><Researchers><Services><Specialist><Therapeutic Agents><Topical Drug Administration><Topical application><apply topically><business-friendly environment><chemical synthesis><collaborative atmosphere><collaborative environment><deliver topically><developmental><drug/agent><inter-institutional><interactive atmosphere><interactive environment><interdisciplinary atmosphere><interdisciplinary environment><malignancy><medical college><medical schools><neoplasm/cancer><peer-group atmosphere><peer-group environment><personnel><pre-clinical study><preclinical study><school of medicine><stem><success><synergism><tool><topical administration><topical delivery><topical drug application><topical drug delivery><topical instillation><topical treatment><treat topically>
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Eric Dinesh Shah

UNIVERSITY OF MICHIGAN AT ANN ARBOR, ANN ARBOR, MI

Exploratory lead · 10/100
Active award
$234,000
FY 2025

Project Title

Rectal evacuation disorders and straining-associated symptoms in bleeding hemorrhoids

Grant Number:

1R03DK143921-01

Activity Code:

R03

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

8/1/2025

End Date:

7/31/2027

Project Abstract

Hemorrhoidal bleeding is one of the most frequent medical complaints and serves as the most clinically relevant presentation of hemorrhoids that leads to several million gastroenterology referrals each year in the US. A typical patient is empirically treated with fiber and topicals; US patients spen...

Research Terms

<21+ years old><Abdomen><Adult><Adult Human><Agreement><Automobile Driving><Award><Biological Markers><Bleeding><Caring><Chronic><Clinical Trials><Clinical Trials Design><Closure by Ligation><Colonoscopy><Consensus><Constipation><Data><Devices><Diagnostic><Disease><Disorder><Endoscopy><Evaluation><Fiber><Funding><Future><Gastroenterologist><Gastroenterology><Guidelines><Health system><Hematochezia><Hemorrhage><Hemorrhoids><Improve Access><Intervention><Intervention Trial><Interventional trial><Intestinal><Intestines><Laboratories><Ligation><Link><London><Manometry><Manometry Biochemistry><Measures><Medical><Medicine><Michigan><Multi-center trial><Multicenter Trials><Operative Procedures><Operative Surgical Procedures><P50 Mechanism><P50 Program><Pathway interactions><Patients><Pelvic><Pelvic Floor><Pelvic Region><Pelvic floor structure><Pelvis><Physiatric Procedure><Physical Medicine Procedure><Physical Therapeutics><Physical therapy><Physiology><Physiotherapy><Population><Position><Positioning Attribute><Prediction of Response to Therapy><Prevalence><Prior Therapy><Procedures><Process><QOL improvement><Questionnaires><Recommendation><Rectum><Research><Research Design><Sample Size><Severities><Specialized Center><Spinal Column><Spine><Study Type><Supplementation><Surgical><Surgical Interventions><Surgical Procedure><Symptom Burden><Symptoms><Testing><Therapy trial><Treatment outcome><Vertebral column><adulthood><associated symptom><backbone><bio-markers><biologic marker><biomarker><blood loss><bowel><clinical practice><clinical relevance><clinical trial enrollment><clinically relevant><co-morbid symptom><co-occuring symptom><comorbid symptom><concurrent symptom><cooccuring symptom><design><designing><driving><endoscopic imaging><experience><health care management><health management><improved><improvements in QOL><improvements in quality of life><indexing><ineffective therapies><ineffective treatment><novel><outcome prediction><participant enrollment><pathway><patient enrollment><patient subclass><patient subcluster><patient subgroups><patient subpopulations><patient subsets><patient subtypes><point of care><point of care testing><predict therapeutic response><predict therapy response><predictive assay><predictive test><primary end point><primary endpoint><prospective><quality of life improvement><response><study design><surgery><symptom association><symptom comorbidity><therapy prediction><treatment prediction><treatment response prediction>
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Paul M Grandgenett

UNIVERSITY OF NEBRASKA MEDICAL CENTER, OMAHA, NE

Exploratory lead · 10/100
Active award
$144,703
FY 2025

Project Title

Critical Resources Provided by UNMC RAP Biorepository Stimulate Cancer Research

Grant Number:

5R50CA211462-10

Activity Code:

R50

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/15/2016

End Date:

8/31/2026

Project Abstract

Project Summary The highly innovative Rapid Autopsy Program (RAP) addresses a major limitation in pancreatic and prostate cancer research: the lack of quality human specimens of cancer representing all stages of disease. This program, led by Dr. Paul M. Grandgenett, which includes rapid collection o...

Research Terms

<Address><Archives><Ascites><Autopsy><Award><Blood><Blood Reticuloendothelial System><Body Tissues><Bp50><CD40><CDW40><Cancer Center><Cancer Patient><Cancer Research Programs><Cancer Research Project><Cancers><Cessation of life><Collaborations><Collection><DNA><Death><Deoxyribonucleic Acid><Disease><Disorder><Distant Cancer><Distant Metastasis><Drug or chemical Tissue Distribution><Focus Groups><Freezing><Funding><Grant><Heterograft><Heterologous Transplantation><Hour><Human><Individual><Institution><International><Investigators><Knowledge><Laboratories><Leadership><Liquid substance><MGC9013><Malignant Neoplasms><Malignant Pancreatic Neoplasm><Malignant Tumor><Malignant neoplasm of pancreas><Malignant neoplasm of prostate><Malignant prostatic tumor><Medical center><Modeling><Modern Man><Molecular><Nebraska><Neoplasm Circulating Cells><Non-Polyadenylated RNA><Normal Tissue><Normal tissue morphology><Oncology><Oncology Cancer><Organ><Organoids><Pancreas Cancer><Pancreatic Cancer><Patients><Play><Postdoc><Postdoctoral Fellow><Primary Neoplasm><Primary Tumor><Process><Prostate><Prostate CA><Prostate Cancer><Prostate Gland><Prostate malignancy><Prostatic Gland><Proteins><R-Series Research Projects><R01 Mechanism><R01 Program><RNA><RNA Gene Products><Research><Research Associate><Research Grants><Research Personnel><Research Project Grants><Research Projects><Research Resources><Research Specimen><Research Training><Researchers><Residual><Residual state><Resources><Ribonucleic Acid><Role><Sampling><Specialist><Specimen><TNFRSF5><TNFRSF5 gene><Tissue Distribution><Tissues><Training><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><Universities><Work><Xenograft><Xenograft procedure><Xenotransplantation><abdominal dropsy><anti-cancer research><associate faculty><associate professor><biobank><biorepository><blood-based biomarker><blood-based marker><cancer research><circulating neoplastic cell><circulating tumor cell><design><designing><experience><fluid><hydroperitonia><hydrops abdominis><innovate><innovation><innovative><liquid><malignancy><mid-career faculty><midcareer faculty><necropsy><neoplasm/cancer><p50><pancreatic malignancy><peritoneal dropsy><peritoneal exudate><post-doc><post-doctoral><post-doctoral trainee><postmortem><programs><research associates><social role><success><volunteer><xeno-transplant><xeno-transplantation>
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Balaji Krishnamachary

JOHNS HOPKINS UNIVERSITY, BALTIMORE, MD

Exploratory lead · 10/100
Active award
$93,367
FY 2025

Project Title

INTEGRATING MOLECULAR BIOLOGY WITH CANCER MOLECULAR IMAGING AND THERANOSTICS

Grant Number:

5R50CA243562-05

Activity Code:

R50

Mechanism:

Non-SBIR/STTR

Agency:

NIH

Start Date:

9/23/2021

End Date:

8/31/2026

Project Abstract

Y at ha A hu Vai ryo The purpose of this R50 application is to provide 6 months effort for Dr. Balaji Krishnamachary as a Research Specialist working with Dr. Bhujwalla as Unit Director. Dr. Krishnamachary was awarded his PhD in 1995, following which he completed his postdoctoral training, first in ...

Research Terms

<Award><Cancers><Career Mobility><DNA Molecular Biology><Doctor of Philosophy><Environment><Funding><Gene Inactivation><Gene Silencing><Gene Transcription><Genes><Genetic Transcription><Goals><Grant><HIF 1><HIF-1 protein><HIF1><HIF1 protein><Hypoxia><Hypoxia Inducible Factor><Hypoxic><ICMIC><In Vitro><Invaded><Investigators><Kidney Cancer><Kidney Carcinoma><Laboratory Research><Malignant Neoplasms><Malignant Tumor><Mentors><Metastasis><Metastasize><Metastatic Lesion><Metastatic Mass><Metastatic Neoplasm><Metastatic Tumor><Methods><Mission><Molecular><Molecular Biology><Molecular Biology Techniques><Monitor><Neoplasm Metastasis><Oxygen Deficiency><Pathology><Ph.D.><PhD><Postdoc><Postdoctoral Fellow><Productivity><R-Series Research Projects><R01 Mechanism><R01 Program><RNA Expression><Renal Cancer><Renal Carcinoma><Research><Research Associate><Research Grants><Research Personnel><Research Project Grants><Research Projects><Researchers><Secondary Neoplasm><Secondary Tumor><Short interfering RNA><Small Interfering RNA><Specialist><Talents><Training><Transcription><Work><cancer imaging><cancer metastasis><cancer microenvironment><cancer progression><career advancement><career transition><hypoxia inducible factor 1><in vivo Cellular and Molecular Imaging Centers><malignancy><medical college><medical schools><molecular imaging><molecule imaging><nano particle delivery><nanoparticle delivered><nanoparticle delivery><neoplasm progression><neoplasm/cancer><neoplastic progression><oncologic imaging><oncology imaging><pediatric department><post-doc><post-doctoral><post-doctoral trainee><post-doctoral training><programs><recruit><research associates><school of medicine><shRNA><short hairpin RNA><siRNA><small hairpin RNA><theranostics><transcriptional silencing><tumor><tumor cell metastasis><tumor imaging><tumor microenvironment><tumor progression>
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GAIL A. BISHOP

IOWA CITY VA MEDICAL CENTER, IOWA CITY, IA

Exploratory lead · 10/100
Active award
$0
FY 2026

Project Title

BLRD Research Career Scientist Award Application

Grant Number:

5IK6BX005392-06

Activity Code:

IK6

Mechanism:

Other

Agency:

VA

Start Date:

10/1/2020

End Date:

9/30/2027

Project Abstract

The overall research program of the applicant seeks to develop new insights and understanding of the key molecular mechanisms regulating the functions of, and interactions between immune cells, with a particular emphasis on B and T lymphocytes, and B cell-derived tumors. The ultimate goal is to appl...

Research Terms

<Abnormal Cell><Adaptor Protein><Adaptor Protein Gene><Adaptor Signaling Protein><Adaptor Signaling Protein Gene><Age><Aging><Antibodies><Area><Autoimmune Status><Autoimmunity><Award><B blood cells><B cell><B cell differentiation factor><B cell malignancy><B cell stimulating factor 2><B cell tumor><B cells><B lymphoid malignancy><B lymphoma><B-Cell Deficiency><B-Cell Differentiation Factor><B-Cell Differentiation Factor-2><B-Cell Lymphocytic Neoplasm><B-Cell Lymphomas><B-Cell Neoplasm><B-Cell Stimulatory Factor-2><B-Cells><B-Lymphocytes><B-cell><B-lineage tumor><BCDF><BSF-2><BSF2><Basic Research><Basic Science><Biological><Biological Markers><Blood><Blood Reticuloendothelial System><Blood leukocyte><Bp50><Burkitt Herpesvirus><Burkitt Lymphoma Virus><CD126 Antigens><CD126 Receptor><CD40><CD40 Receptor-Associated Factor 1><CD40bp Protein><CDW40><CRAF1 Protein><Cachectin Receptors><Cancer Treatment><Cancers><Cell Aging><Cell Body><Cell Communication and Signaling><Cell Senescence><Cell Signaling><Cell Surface Receptors><Cell Survival><Cell Viability><Cells><Cellular Aging><Cellular Senescence><Characteristics><Chronic><Clinic><Clinical><Clinical Treatment><Clinical Treatment Moab><Clinical Trials><Collaborations><Communicable Diseases><Communities><Community Participation><D-Glucose><DNA mutation><Development><Dextrose><Disease><Disorder><Doctor of Philosophy><EB virus><EBOV><EBV><Ebola virus><Ebola-like Viruses><Educational process of instructing><Ensure><Epstein Barr Virus><Event><Funding><Future><Gene Transcription><General Population><General Public><Genes><Genetic Change><Genetic Transcription><Genetic defect><Genetic mutation><Germinoblastic Sarcoma><Germinoblastoma><Glucose><Goals><Graft Rejection><Grant Review><HHV-4><HHV4><HPGF><Health><Hepatocyte-Stimulating Factor><Human><Human Herpesvirus 4><Hybridoma Growth Factor><IFN-beta 2><IFNB2><IL-6><IL-6 Receptors><IL6 Protein><IL6 Receptors><Immune><Immune response><Immunes><Immunity><Industry><Infection><Infectious Diseases><Infectious Disorder><Infectious Mononucleosis Virus><Inflammatory><Interleukin 6 Receptor><Interleukin-6><Intermediary Metabolism><International><Intracellular Communication and Signaling><Investigation><Investigators><Iowa><Knowledge><LAP-1 Protein><LMP1><LYP gene><LYP protein><Laboratories><Leadership><Learning><Leukocytes><Leukocytes Reticuloendothelial System><Life><Lymphatic cell><Lymphocyte><Lymphocyte Biology><Lymphocyte Function><Lymphocytic><Lymphoid Phosphatase><Lymphoma><MGC9013><MGI-2><Malignant Cell><Malignant Lymphoma><Malignant Neoplasm Therapy><Malignant Neoplasm Treatment><Malignant Neoplasms><Malignant Pancreatic Neoplasm><Malignant Tumor><Malignant neoplasm of pancreas><Manuscripts><Marrow leukocyte><Measures><Mediating><Medical><Mentors><Metabolic Processes><Metabolism><Mice><Mice Mammals><Modern Man><Molecular><Monoclonal Antibodies><Mouse Strains><Multiple Myeloma><Murine><Mus><Mutation><Myeloid Differentiation-Inducing Protein><Nature><Non-Receptor Type 22 Protein Tyrosine Phosphatase><Non-Receptor Type 8 Protein Tyrosine Phosphatase><Nuclear Protein><Oncogenic><Oncologist><Orthoebolavirus><PEP gene><PEP protein><PTPN22><PTPN22 gene><PTPN8><Pancreas Cancer><Pancreatic Cancer><Pathogenesis><Pathway interactions><Pest-Domain Phosphatase><Ph.D.><PhD><Phenotype><Phosphatases><Phosphohydrolases><Phosphomonoesterases><Phosphoric Monoester Hydrolases><Physicians><Plasma-Cell Myeloma><Plasmacytoma Growth Factor><Play><Population><Post-Translational Modification Protein/Amino Acid Biochemistry><Post-Translational Modifications><Post-Translational Protein Modification><Post-Translational Protein Processing><Posttranslational Modifications><Posttranslational Protein Processing><Predisposition><Preparation><Process><Progress Reports><Protein Modification><Proteins><Publications><RNA Expression><Receptor Protein><Regulation><Regulatory Protein><Replicative Senescence><Research><Research Personnel><Researchers><Resistance><Reticulolymphosarcoma><Role><Scientific Publication><Scientific Societies><Scientist><Services><Signal Transduction><Signal Transduction Systems><Signaling><Signaling Factor Proto-Oncogene><Signaling Pathway Gene><Signaling Protein><Source><Specialist><Susceptibility><T-Cells><T-Lymphocyte><TNF Receptor Family Protein><TNF Receptor Superfamily><TNF Receptors><TNF receptor-associated factor 3><TNFR><TNFRSF5><TNFRSF5 gene><TRAF-3><TRAF3><Teaching><Therapeutic><Toxin><Transcription><Translating><Translations><Transplant Rejection><Transplantation Rejection><Tumor Cell><Tumor Necrosis Factor Receptor><Tumor Necrosis Factor Receptor Family><Tumor Necrosis Factor Receptor Superfamily><Tumor Necrosis Factor Receptor Superfamily Member 5 Gene><Tumor Suppressor Proteins><Universities><Veterans><Viral Diseases><Virus Diseases><White Blood Cells><White Cell><Work><adapter protein><ages><anti-cancer therapy><bio-markers><biologic><biologic marker><biological signal transduction><biomarker><c myc><c-myc Genes><cancer cell><cancer therapy><cancer-directed therapy><career><cell killing><cell type><clinical applicability><clinical application><clinical intervention><clinical relevance><clinical therapy><clinically relevant><cmyc><developmental><effective therapy><effective treatment><fighting><genetic regulatory protein><genome mutation><glucose metabolism><glucose uptake><host response><humoral immunity deficiency><immune system response><immunoresponse><improved><inhibitor><insight><interest><interferon beta 2><loss of function><lymph cell><mAbs><malignancy><military veteran><monoclonal Abs><myeloma><myelomatosis><neoplasm/cancer><neoplastic cell><news><next generation><p50><pancreatic malignancy><pathway><preparations><prevent><preventing><programs><protein function><receptor><recruit><regulatory gene product><replicative aging><resistant><restraint><small molecular inhibitor><small molecule inhibitor><social role><thymus derived lymphocyte><translation><treatment trial><trial regimen><trial treatment><tumor><tumor suppressor><v-myc Avian Myelocytomatosis Viral Oncogene Cellular Homolog><veteran population><viral infection><virus infection><virus-induced disease><white blood cell><white blood corpuscle>
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HIDEKAZU TSUKAMOTO

VA GREATER LOS ANGELES HEALTHCARE SYSTEM, LOS ANGELES, CA

Exploratory lead · 10/100
Active award
$0
FY 2025

Project Title

BLR&D Research Career Scientist Award Application

Grant Number:

2IK6BX004205-08

Activity Code:

IK6

Mechanism:

Other

Agency:

VA

Start Date:

4/1/2018

End Date:

3/31/2030

Project Abstract

This application is for a competitive renewal of the SCRS program of Dr. Hidekazu (Hide) Tsukamoto. Dr. Tsukamoto continues to make significant contributions to the Medical Research Program of the Department of Veterans Affairs via two distinct yet interactive efforts: firstly as a Research Physiolo...

Research Terms

<Address><Affinity><Alcohol Chemical Class><Alcohol associated hepatitis><Alcohol hepatitis><Alcohol induced hepatitis><Alcohol related hepatitis><Alcoholic Hepatitis><Alcoholic Liver Diseases><Alcohols><Animals><Area><Award><Beta Cadherin-Associated Protein><Beta-1 Catenin><Book Chapters><CRISPR approach><CRISPR based approach><CRISPR method><CRISPR methodology><CRISPR technique><CRISPR technology><CRISPR tools><CRISPR-CAS-9><CRISPR-based method><CRISPR-based technique><CRISPR-based technology><CRISPR-based tool><CRISPR/CAS approach><CRISPR/Cas method><CRISPR/Cas technology><CRISPR/Cas9><CRISPR/Cas9 technology><CTNNB><CTNNB1><CTNNB1 gene><CUL-2><CYP1B1><CYP1B1 gene><California><Cas nuclease technology><Causality><Cell Body><Cell Fate Control><Cell Fate Regulation><Cells><Cirrhosis><Clonal Evolution><Clustered Regularly Interspaced Short Palindromic Repeats approach><Clustered Regularly Interspaced Short Palindromic Repeats method><Clustered Regularly Interspaced Short Palindromic Repeats methodology><Clustered Regularly Interspaced Short Palindromic Repeats technique><Clustered Regularly Interspaced Short Palindromic Repeats technology><Collaborations><Copy Number Polymorphism><Core Grant><Development><Disease><Disorder><EDS-4-hydroxylase><Education and Outreach><Education and Training><Ethanol-induced hepatitis><Etiology><Fibroblasts><Funding><Gastroenterology><Generalized Growth><Generations><Genetic><Goals><Grant><Growth><Health><Health Care><Health Care Systems><Hepatic Cancer><Hepatic Cells><Hepatic Disorder><Hepatic Fibrogenesis><Hepatic Neoplasms><Hepatic Parenchymal Cell><Hepatic Stellate Cell><Hepatitis><Hepatocyte><Hepatology><High Prevalence><Home><Human><Hybrids><Immunosuppression><Immunosuppression Effect><Immunosuppressive Effect><In vivo analysis><Individual><Inflammatory><Institution><Instruction and Outreach><Investigation><Investigators><Ito Cell><Lineage Tracing><Liver Cells><Liver Fibrosis><Liver diseases><Liver neoplasms><Los Angeles><Malignant Cell><Malignant neoplasm of liver><Medical><Medical Research><Mice><Mice Mammals><Modality><Modeling><Modern Man><Molecular><Murine><Mus><NIAAA><NIH><NR4A2><NR4A2 gene><NR4A2 protein><National Institute on Alcohol Abuse and Alcoholism><National Institutes of Health><Nature><Nuclear Proteins><Nur-related factor 1><Nurr1><Nurr1 nuclear receptor><Organoids><Outcome><PRO2286><Pancreatic Diseases><Pancreatic Disorder><Pathogenesis><Pathway interactions><Patients><Peer Review><Phenotype><Pilot Projects><Population><Pre-Clinical Model><Preclinical Models><Prevention><Preventive><Publications><Publishing><R24><Receptor Protein><Regulation><Repression><Research><Research Personnel><Research Resources><Research Support><Researchers><Resources><Role><Science><Scientific Publication><Scientist><Services><Shapes><Site><Source><Stearate Desaturase><Stearoyl-CoA Desaturase><Stearyl-CoA Desaturase><Testing><Therapeutic><Tissue Growth><Training and Education><Training and Outreach><Tumor Cell><Tumor Promotion><Tutoring and Outreach><United States Department of Veterans Affairs><United States National Institutes of Health><United States Veterans Administration><Veterans><Veterans Administration><Veterans Affairs><alcohol induced hepatic injury><alcohol induced liver disorder><alcohol induced liver injury><alcohol related liver disease><alcohol use disorder><alcohol-associated liver disease><alcohol-induced hepatic dysfunction><alcohol-induced liver disease><alcohol-induced liver dysfunction><alcohol-mediated liver dysfunction><alcohol-mediated liver injury><alcohol-related liver disease><alcoholic liver injury><base><bases><beta cat><beta catenin><cancer cell><cancer microenvironment><career><causation><cell lineage analysis><cell lineage mapping><cell lineage tracing><cell lineage tracking><cell type><cellular lineage mapping><cellular lineage tracking><cirrhotic><community center><community centers><copy number variant><copy number variation><cytochrome P450 CYP1B1><cytochrome P4501B1><delta-9 Desaturase><developmental><disease causation><estradiol 17-sulfate 4-hydroxylase><estradiol-4-hydroxylase><estrogen 4-hydroxylase><ethanol induced hepatic injury><ethanol induced liver disorder><ethanol induced liver injury><ethanol liver disease><ethanol use disorder><ethanol-induced hepatic dysfunction><ethanol-induced liver disease><ethanol-induced liver dysfunction><ethanol-mediated liver dysfunction><ethanol-mediated liver injury><extracellular vesicles><fibrotic liver><hepatic disease><hepatic fibrosis><hepatic inflammation><hepatic neoplasia><hepatic neoplasm><hepatic tumor><hepatopathy><homes><immune suppression><immune suppressive activity><immune suppressive function><immunosuppressive activity><immunosuppressive function><immunosuppressive response><improved><in vivo evaluation><in vivo testing><inflamed liver><innovate><innovation><innovative><insight><knock-down><knockdown><liver cancer><liver disorder><liver fibrogenesis><liver inflammation><liver malignancy><liver tumor><malignant liver tumor><mortality><mouse model><murine model><neoplastic cell><new drug target><new drug treatments><new druggable target><new drugs><new pharmacological therapeutic><new pharmacotherapy target><new therapeutic target><new therapeutics><new therapy><new therapy target><next generation therapeutics><novel><novel drug target><novel drug treatments><novel druggable target><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel pharmacotherapy target><novel therapeutic target><novel therapeutics><novel therapy><novel therapy target><nuclear receptor-related factor 1><ontogeny><pancreas disorder><paracrine><pathway><pharmacologic><pilot study><prevent><preventing><programs><receptor><scRNA sequencing><scRNA-seq><single cell RNA-seq><single cell RNAseq><single cell expression profiling><single cell transcriptomic profiling><single-cell RNA sequencing><social role><tumor><tumor growth><tumor microenvironment><vesicle release><vesicular release><β-catenin>
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Jonathan N. Myers

VETERANS ADMIN PALO ALTO HEALTH CARE SYS, PALO ALTO, CA

Exploratory lead · 10/100
Active award
$0
FY 2025

Project Title

Senior Research Career Scientist

Grant Number:

5IK6RX002477-10

Activity Code:

IK6

Mechanism:

Other

Agency:

VA

Start Date:

10/1/2016

End Date:

9/30/2030

Project Abstract

The overarching goals of Dr. Myers’ research program are to apply exercise therapy and lifestyle intervention to help restore function, reduce disability, and reduce health care costs in Veterans with chronic disease. These areas include diagnostic and prognostic applications of cardiopulmonary exer...

Research Terms

<Abdominal Aortic Aneurysm><Actin-Activated ATPase><Address><Affect><Age><American male><American man><American men><Angiogram><Angiography><Angioplasty><Area><Asymmetric Septal Hypertrophy><Back><Basic Research><Basic Science><Cardiac Diseases><Cardiac Disorders><Cardiac Failure Congestive><Cardiac rehabilitation><Cardiology><Cardiopulmonary><Cardiovascular Diseases><Cause of Death><Chronic><Chronic Disease><Chronic Illness><Chronic Kidney Failure><Chronic Renal Disease><Chronic Renal Failure><Clinical><Clinical Services><Congestive Heart Failure><Coronary Arteriosclerosis><Coronary Artery Disease><Coronary Artery Disorder><Coronary Atherosclerosis><Cost Savings><Data><Data Bases><Data Set><Databases><Diagnosis><Diagnostic><Disease><Disorder><Dorsum><Epidemiology><Evaluation><Exercise><Exercise Test><Exercise Therapy><Fostering><Funding><General Population><General Public><Generalized Growth><Goals><Graph><Growth><Guidelines><Habilitation><Health><Health Care Costs><Health Costs><Heart Decompensation><Heart Diseases><Heart failure><Hereditary ventricular hypertrophy><High Prevalence><History><Home><Human><Hypertrophic Cardiomyopathy><Hypertrophic Obstructive Cardiomyopathy><Idiopathic Hypertrophic Subvalvular Stenosis><Idiopathic hypertrophic subaortic stenosis><Interdisciplinary Research><Interdisciplinary Study><Internal Medicine><Intervention Trial><Interventional trial><Investigation><Investigators><Journals><Kidney Diseases><Left><Leg Pain><Life Style><Lifestyle><Magazine><Medical Rehabilitation><Medicine><Modern Man><Molecular><Multidisciplinary Collaboration><Multidisciplinary Research><Myosin ATPase><Myosin Adenosine Triphosphatase><Myosin Adenosinetriphosphatase><Myosins><NHLBI><NIH><National Heart, Lung, and Blood Institute><National Institutes of Health><Nephropathy><New England><Northeastern United States><Obesity><On-Line Systems><Online Systems><Operative Procedures><Operative Surgical Procedures><Outcome><P50 Mechanism><P50 Program><Pain in lower limb><Paper><Patients><Pattern><Peer Review><Peripheral><Peripheral arterial disease><Persons><Physical Fitness><Physical Function><Physical activity><Physiologic><Physiological><Population><Prevalence><Prevention><Productivity><Publications><Publishing><QOL><QOL improvement><Quality of life><R-Series Research Projects><R01 Mechanism><R01 Program><Randomized><Recommendation><Recording of previous events><Registries><Rehabilitation><Rehabilitation therapy><Renal Disease><Reporting><Research><Research Grants><Research Personnel><Research Project Grants><Research Projects><Research Resources><Researchers><Resources><Role><Rural Health><Schedule><Science><Scientific Publication><Scientist><Seminal><Services><Site><Source><Specialized Center><Spinal Cord Trauma><Spinal Trauma><Spinal cord injured><Spinal cord injury><Stents><Surgical><Surgical Interventions><Surgical Procedure><System><Temporal trend><Test Result><Therapeutic exercise><Time trend><Tissue Growth><Transducers><Transplantation><Traumatic Myelopathy><Trends over time><U.S. Males><US Men><US male><United States National Institutes of Health><Veterans><Walking><abdominal aorta><adiposity><ages><angiographic imaging><atherosclerotic coronary disease><cardiac failure><cardiac rehab><cardiac rhythm><cardiorespiratory fitness><cardiorespiratory health><cardiovascular disorder><career><chronic disorder><chronic heart failure><chronic kidney disease><clinical applicability><clinical application><clinical center><clinical database><clinical relevance><clinically relevant><cohort><coronary arterial disease><corpulence><data base><decrease disability><decrease in disability><design><designing><disability><disability reduction><epidemiologic><epidemiological><exercise capacity><exercise intervention><exercise treatment><fitness><functional restoration><health application><health organization><heart disorder><heart rehabilitation><heart rhythm><histories><homes><hospitalization rates><hypertrophic myocardiopathy><improved><improvements in QOL><improvements in quality of life><indexing><intraluminal angioplasty><kidney disorder><lessen disability><life style intervention><life-style factor><lifestyle factors><lifestyle intervention><lung rehabilitation><male><males in America><males in the U.S.><males in the US><males in the USA><males in the United States><men in America><men in the U.S.><men in the US><men in the USA><men in the United States><mild cognitive disorder><mild cognitive impairment><minimize disability><mitigate disability><multidisciplinary><novel><online computer><ontogeny><peripheral artery disease><physical activity intervention><prognostic><programs><prospective><pulmonary rehabilitation><quality of life improvement><randomisation><randomization><randomly assigned><reduction in disability><rehab therapy><rehabilitative><rehabilitative therapy><relational database><renal disorder><response><restore function><restore functionality><restore lost function><slow disability><social role><surgery><telehealth><transplant><treated with exercise><web based><♂>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Jie Fan

VETERANS HEALTH ADMINISTRATION, PITTSBURGH, PA

Exploratory lead · 10/100
Active award
$0
FY 2025

Project Title

BLRD Research Career Scientist Award Application

Grant Number:

5IK6BX006297-03

Activity Code:

IK6

Mechanism:

Other

Agency:

VA

Start Date:

4/1/2023

End Date:

3/31/2028

Project Abstract

PROJECT SUMMARY Jie Fan, M.D., M.Sc. has been working in the VA Pittsburgh Healthcare System (VAPHS) since 2003 and is a VA Research Career Scientist, a Director of the Surgical Research Program, a Vice- Chair of the Institutional Animal Care and Use Committee, a Mentor of VA Career Development Awa...

Research Terms

<Acquired brain injury><Acute><Acute Lung Injury><Acute Pulmonary Injury><American><Apoplexy><Area><Autoimmune Diseases><Award><Basic Research><Basic Science><Biologic Sciences><Biological Sciences><Bioscience><Bleeding><Brain Injuries><Brain Vascular Accident><Cause of Death><Cell Body><Cell Communication and Signaling><Cell Death><Cell Differentiation><Cell Differentiation process><Cell Signaling><Cells><Cerebral Stroke><Cerebrovascular Apoplexy><Cerebrovascular Stroke><Cessation of life><Chronic><Clinical><Clinical Research><Clinical Study><Collaborations><Communication><Death><Development><Disease><Disorder><Doctor of Medicine><Doctor of Philosophy><Drugs><Dysfunction><Education><Educational aspects><European><Faculty><Failure><Functional disorder><Funding><Goals><Government><Grant Review><Health><Health Care><Health Care Systems><Hemorrhage><Hepatology><IACUC><Immunology><Infection><Inflammation><Innate Immunity><Institution><Institutional Animal Care and Use Committee><International><Intervention><Intracellular Communication and Signaling><Investigators><Journals><Laboratories><Life Sciences><Literature><M.D.><Magazine><Medical><Medication><Medicine><Mentors><Molecular><NIH><National Institutes of Health><Native Immunity><Natural Immunity><Nature><Non-Specific Immunity><Nonspecific Immunity><Operative Procedures><Operative Surgical Procedures><Organ><Paper><Pathogenesis><Patients><Peer Review><Ph.D.><PhD><Pharmaceutical Preparations><Phase><Physicians><Physiopathology><Play><Postdoc><Postdoctoral Fellow><Preventative intervention><Principal Investigator><Productivity><Publications><Publishing><R-Series Research Projects><R01 Mechanism><R01 Program><Reporting><Research><Research Associate><Research Grants><Research Personnel><Research Project Grants><Research Projects><Researchers><Review Committee><Role><Science><Scientific Publication><Scientist><Sepsis><Signal Transduction><Signal Transduction Systems><Signaling><Spinal Injuries><Stroke><Study Section><Surgical><Surgical Interventions><Surgical Procedure><Systemic Inflammatory Response Syndrome><Therapeutic Intervention><Time><Trauma><Trauma patient><United States National Institutes of Health><Universities><Veterans><Work><after sepsis><after septic><autoimmune condition><autoimmune disorder><autoimmunity disease><biological signal transduction><blood loss><brain attack><brain damage><brain-injured><career><career development><cellular differentiation><cerebral vascular accident><cerebrovascular accident><clinical investigation><conference><convention><develop therapy><developmental><drug/agent><editorial><following sepsis><following septic><full professor><human disease><individuals with sepsis><intervention development><intervention for prevention><intervention therapy><member><military veteran><mortality><necrocytosis><new drug target><new druggable target><new pharmacotherapy target><new therapeutic target><new therapy target><novel><novel drug target><novel druggable target><novel pharmacotherapy target><novel therapeutic target><novel therapy target><pathophysiology><patient population><patients with sepsis><peer><people with sepsis><post sepsis><post septic><post-doc><post-doctoral><post-doctoral trainee><post-trauma><posttrauma><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><programs><prophylactic><research associates><senior faculty><sepsis groups><sepsis patients><sepsis population><sepsis subjects><septic group><septic individuals><septic patients><septic people><septic population><septic subject><social role><spine injury><stroked><strokes><subjects with sepsis><summit><surgery><surgical research><symposia><symposium><therapy development><treatment development><vertebral injury><veteran population><visiting scholar>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Giulio Maria Pasinetti

JAMES J PETERS VA MEDICAL CENTER, BRONX, NY

Exploratory lead · 10/100
Active award
$0
FY 2025

Project Title

BLR&D Research Career Scientist Award Application

Grant Number:

5IK6BX003785-09

Activity Code:

IK6

Mechanism:

Other

Agency:

VA

Start Date:

4/1/2017

End Date:

3/31/2031

Project Abstract

PROJECT SUMMARY/ABSTRACT: Dr. Pasinetti is a Senior Research Career Scientist and Director, Basic and Biomedical Research and Training, Geriatric Research, Education and Clinical Center (GRECC) at the James J. Peters Veterans Affairs Medical Center (JJPVAMC). He is also the Saunders Family Chair of ...

Research Terms

<2-Phenyl-Benzopyrans><2-Phenyl-Chromenes><21+ years old><AD dementia><AD related dementia><ADRD><Acceleration><Address><Adult><Adult Human><Affective Disorders><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's dementia and related dementia><Alzheimer's dementia or related dementia><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimers Dementia><Amentia><Amyotrophic lateral sclerosis and frontotemporal degeneration><Amyotrophic lateral sclerosis and frontotemporal dementia><Anxiety><Automobile Driving><Award><BBB permeabilization><BBB permeable><Basic Research><Basic Science><Behavior><Biological><Biomedical Research><Blood Plasma><Botanicals><Brain><Brain Nervous System><Brain Trauma><Cell Body><Cells><Chronic><Clinical Trials><Cognitive><Cognitive Disturbance><Cognitive Impairment><Cognitive decline><Cognitive deficits><Cognitive function abnormal><Collaborations><Complex><Data><Degenerative Neurologic Disorders><Dementia><Department of Defense><Development><Dietary Formulations><Dietary Polyphenol><Disease><Disorder><Disturbance in cognition><Dose><Drug Kinetics><Drugs><Dysfunction><Education><Educational aspects><Elderly><Encephalon><Endowment><Environmental Toxin><Exposure to><FTD dementia><FTD/ALS><FTLD/ALS><Family><Fatigue><Flavonoids><Frontal Temporal Dementia><Frontotemporal Dementia><Frontotemporal Lobar Degeneration/Amyotrophic lateral sclerosis><Functional disorder><Funding><Future><GI microbiome><Genomics><Geriatrics><Goals><Grant><Grapes><Gulf War><Gulf War Illness><Gulf War Syndrome><Health><Hortega cell><Hu-mABs><Human><IMiD><Immune><Immune Diseases><Immune Disorders><Immune Dysfunction><Immune System Diseases><Immune System Disorder><Immune System Dysfunction><Immune System and Related Disorders><Immune Targeting><Immune mediated therapy><Immune modulatory therapeutic><Immune signaling><Immune system><Immunes><Immunologic Diseases><Immunological Diseases><Immunological Dysfunction><Immunological System Dysfunction><Immunologically Directed Therapy><Immunotherapy><Impaired cognition><Impairment><Individual><Inflammation><Inflammation Mediators><Inflammatory><Inflammatory Response><Infrastructure><Innate Immune Response><Investigation><Journals><Juice><Lack of Energy><Long-Term Effects><Magazine><Manuscripts><Medical center><Medication><Mental Depression><Mental health promotion><Microglia><Modeling><Modern Man><Molecular><Mood Disorders><Moods><NIH><National Institutes of Health><Natural Products><Nerve Cells><Nerve Degeneration><Nerve Unit><Nervous System Degenerative Diseases><Nervous System Diseases><Nervous System Disorder><Neural Cell><Neural Degenerative Diseases><Neural degenerative Disorders><Neurocyte><Neurodegenerative Diseases><Neurodegenerative Disorders><Neurologic Degenerative Conditions><Neurologic Disorders><Neurological Disorders><Neurology><Neuron Degeneration><Neurons><Neurosciences><Neurotoxins><Operation Desert Shield><Operation Desert Storm><Outcome><Pathogenesis><Pathway interactions><Peer Review><Peripheral><Persian Gulf Syndrome><Pharmaceutical Preparations><Pharmacokinetics><Physiologic><Physiological><Physiopathology><Plasma><Plasma Serum><Predisposition><Preparation><Primary Senile Degenerative Dementia><Psychiatry><Psychologic Stress><Psychological Stress><Publications><Recruitment Activity><Research><Reticuloendothelial System, Serum, Plasma><Risk Factors><Role><Safety><Scientific Publication><Scientist><Seminal><Stress><Stressful Event><Structure><Susceptibility><Symptoms><Testing><Therapeutic><Toxic Environmental Agents><Toxic Environmental Substances><Toxin><Training><Traumatic Brain Injury><United States Department of Veterans Affairs><United States National Institutes of Health><United States Veterans Administration><Upregulation><Validation><Veterans><Veterans Administration><Veterans Affairs><active recruitment><adulthood><advanced age><aging process><amyotrophic lateral sclerosis with frontotemporal dementia><amyotrophic lateral sclerosis/FTLD><amyotrophic lateral sclerosis/frontotemporal dementia><amyotrophic lateral sclerosis/ftd><anti-depressant agent><anti-depressant drugs><anti-depressants><anti-depressive agents><biologic><blood-brain barrier permeabilization><blood-brain barrier permeable><bloodbrain barrier permeabilization><bloodbrain barrier permeable><build resilience><build resiliency><career><clinical center><clinical investigation><cognitive defects><cognitive disability><cognitive dysfunction><cognitive function><cognitive loss><cognitively disabled><cytokine><degenerative diseases of motor and sensory neurons><degenerative neurological diseases><depressed immune reaction><depressed immune response><depression><depression model><depression prevention><depressive model><design><designing><develop resilience><develop resiliency><developmental><diet supplement><dietary supplements><digestive tract microbiome><dosage><driving><drug discovery><drug/agent><enhance resilience><enhance resiliency><enteric microbiome><environmental toxicant><experience><facilitate resilience><forging><front temporal dementia><frontal lobe dementia><frontotemporal dementia-amyotrophic lateral sclerosis><frontotemporal lobar degeneration dementia><frontotemporal lobar dementia><frontotemporal lobar dementia amyotrophic lateral sclerosis><frontotemporal lobe degeneration associated with dementia><gastrointestinal microbiome><geriatric><geriatric medicine><gitter cell><gut microbiome><gut-associated microbiome><humAbs><human mAbs><human monoclonal antibodies><human monoclonals><immune depression><immune modulating agents><immune modulating drug><immune modulating therapeutics><immune modulatory agents><immune modulatory drugs><immune therapeutic approach><immune therapeutic interventions><immune therapeutic regimens><immune therapeutic strategy><immune therapy><immune-based therapies><immune-based treatments><immuno therapy><immunodepression><immunomodulating agents><immunomodulating drugs><immunomodulator agent><immunomodulator drug><immunomodulator medication><immunomodulator prodrug><immunomodulator therapeutic><immunomodulatory agents><immunomodulatory drugs><immunomodulatory therapeutics><improve resilience><improve resiliency><improved><in vivo><increase resilience><increase resiliency><indexing><indicators of resilience><inflammation marker><inflammatory marker><inflammatory mediator><insight><intestinal biome><intestinal microbiome><marker of biological resilience><markers underlying resilience><medical college><medical schools><mesoglia><microglial cell><microgliocyte><military service><military veteran><mouse model><murine model><naturally occurring product><neural degeneration><neural inflammation><neuro-vascular damage><neuro-vascular injury><neurodegeneration><neurodegenerative><neurodegenerative illness><neuroinflammation><neuroinflammatory><neurological degeneration><neurological disease><neuronal><neuronal degeneration><neuropathologic><neuropathological><neuropathology><neuropsychiatric disease><neuropsychiatric disorder><neurotoxicant><neurovascular damage><neurovascular injury><new drug treatments><new drugs><new pharmacological therapeutic><new therapeutics><new therapy><next generation therapeutics><novel><novel drug treatments><novel drugs><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><nutritional supplement><pathophysiology><pathway><perivascular glial cell><phase 1 trial><phase I trial><polyphenol><pre-clinical><pre-clinical study><preclinical><preclinical study><preparations><prevent><preventing><primary degenerative dementia><professor><programs><promote resilience><promote resiliency><psychologic><psychologic trauma><psychological><psychological shock><psychological trauma><resilience><resilience biomarker><resilience development><resilience marker><resilient><response><school of medicine><senile dementia of the Alzheimer type><senior citizen><signatures of resilience><social role><stressful experience><stressful life event><stressful life experience><targeted drug therapy><targeted drug treatments><targeted therapeutic><targeted therapeutic agents><targeted therapy><targeted treatment><therapeutic evaluation><therapeutic target><therapeutic testing><translational study><traumatic brain damage><validation studies><validations><veteran population>
View Full Project Details on NIH Reporter
Public NIH records usually do not include a direct email address. For outreach, verify the investigator through their institution profile, lab website, recent publications, or official NIH project page.

Search NIH grants by PI name

Looking for a specific principal investigator? The keyword search above looks up funded projects by topic. To search NIH grants by PI name (last name, first + last name, or partial name) and see every active and recent NIH award for that researcher, use the dedicated PI Funding Status tool.

How to Use PI Funding Data for Career Decisions

Finding the right principal investigator is one of the most important decisions in an academic career. Whether you are a postdoc looking for a mentor, a graduate student choosing a rotation lab, or a collaborator seeking a co-PI, NIH funding data provides objective signals about which investigators have active research programs and resources to support new team members.

A PI with a recently awarded R01 or equivalent grant is more likely to have budget for new personnel than one whose funding ended two years ago. The activity code tells you the type of grant: R01 and R35 awards typically support multiple lab members, while K-series awards are individual career development grants that may not fund additional positions. Understanding these distinctions helps you interpret search results accurately.

Look beyond the dollar amount. A $500,000 per year R01 at a high-cost institution may support fewer positions than a $300,000 award at a university with lower overhead rates. The project abstract and public health relevance statement reveal whether the PI's research direction aligns with your interests and expertise.

Understanding PI Grant Portfolios

A PI's grant portfolio reveals more than individual awards. Investigators with multiple active grants often run larger labs with more diverse projects, which can mean more opportunities for trainees. However, a PI with a single well-funded grant may offer more focused mentorship and a clearer path to publications.

Multi-PI grants (those with more than one principal investigator listed) indicate collaborative research and may involve trainees from multiple institutions. These can be excellent opportunities for interdisciplinary training but may also mean split attention from any single mentor.

Pay attention to the timing of awards. A PI who just received a new five-year R01 is in a different position than one whose grant ends next year. New awards often correspond to lab expansion and active recruiting, making them ideal targets for job seekers. The start and end dates shown in each result help you assess this timing.

Best Practices for Contacting Funded PIs

Once you identify a promising PI through this tool, the next step is outreach. NIH public records do not include email addresses, but you can usually find contact information through the PI's institutional profile page, lab website, or recent publications. Google Scholar, PubMed, and the PI's department website are reliable starting points.

When reaching out, reference the specific grant that caught your attention. Mentioning the project title and explaining how your skills relate to the funded work shows that you have done your homework. Keep your initial message concise: introduce yourself, explain your interest, attach your CV, and ask whether they anticipate openings.

Timing matters. Contacting a PI within the first year of a new award is ideal, as this is when they are most likely to be recruiting. If you find multiple promising PIs in the same field, prioritize those with the most recent award notices and activity codes that support trainee positions such as R01, U01, or P-series grants.

Frequently Asked Questions About PI Search

What does the opportunity score mean?

The opportunity score is a heuristic that combines award recency, funding amount, activity code type, and project characteristics to estimate how actionable a result might be for job seekers or collaborators. Higher scores suggest stronger signals, but always verify by reading the abstract and checking the PI's current lab page.

Why can't I find a PI I know has funding?

Name variations are the most common cause. Try searching with just the last name, or use different formats like "Smith, John" versus "John Smith." Some PIs also publish under different name variations or may have awards under a previous institutional affiliation.

Does this tool show all NIH-funded PIs?

The tool searches NIH RePORTER data for the keyword and year range you specify. It returns PIs whose funded projects match your search terms. PIs with grants in unrelated areas or whose projects use different terminology will not appear in keyword-filtered results.

What is the difference between "Likely hiring" and "Training-friendly" filters?

"Likely hiring" flags PIs with large new awards or activity codes typically associated with lab expansion. "Training-friendly" identifies awards that include training components or are at institutions known for postdoctoral programs. Both are heuristic filters to help prioritize your outreach.

How to use this well

Start broad, then narrow. Search a field first, then refine by timeframe once you understand who is currently active.

After you find a promising PI, cross-check them in Check PI Funding and review their institution, mechanism type, and project abstracts before reaching out.

What a match means

A result means the keyword appears relevant to the funded project data we searched. It does not guarantee the PI is hiring or that the grant is still active.

Use the abstract, award year, mechanism, and organization context to decide whether the record is strategically relevant.

Data limits

NIH records can lag, institutional names can vary, and some investigators publish or file awards under multiple name formats.

For details on source coverage and refresh cadence, read Data & Methodology.

Related guides

Companion guides for turning a PI search result into useful outreach or a job lead.

Career Guide8 min read

How Postdocs Can Find PIs with New NIH Funding

A tactical job-search guide for identifying recently funded labs, judging fit, and timing outreach to principal investigators.

Read guide
Career Guide7 min read

How to Contact a PI: Finding Emails and Crafting the Perfect Message

Emailing strategies, outreach examples, and a workflow for turning NIH funding signals into focused PI conversations.

Read guide
Career Guide10 min read

How to Read a New NIH Award Like a Hiring Signal

A practical framework for using newly funded NIH awards to judge whether a lab may be expanding, hiring, or worth contacting now.

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Funding Strategy16 min read

How to Find NIH Funding Opportunities: A Step-by-Step Guide for Researchers

Learn how to find NIH funding opportunities using the NIH Guide, Grants.gov, FOAs, NIH RePORTER, and program officer outreach.

Read guide

Recently Funded Labs in Trending Areas

Principal investigators who received NIH awards in the last 90 days, organized by research area. Use this as a starting point for postdoc searches, collaborator outreach, or competitor scans. Counts and labs refresh daily.

Alzheimer's disease

Neurodegeneration, biomarkers, and disease-modifying therapies.

  • Carlos Cruchaga — WASHINGTON UNIVERSITY, MO
    CONGAS: "Caribbean Omics 'N' Genomics for Alzheimer Study"
    $101,153 · awarded Feb 25, 2026 · 3U01AG084514-01A1S1
  • Carlos Cruchaga — WASHINGTON UNIVERSITY, MO
    CONGAS: "Caribbean Omics 'N' Genomics for Alzheimer Study"
    $3,086,339 · awarded Feb 19, 2026 · 1U01AG084514-01A1
  • HARALD SONTHEIMER — UNIVERSITY OF VIRGINIA, VA
    Extracellular matrix and memory impairments in Alzheimer disease
    $709,066 · awarded Apr 7, 2026 · 5R01AG085359-03
  • Keith Josephs — MAYO CLINIC ROCHESTER, MN
    The neurobiology of two distinct subtypes of neurodegenerative apraxia of speech: phenotypes of Alzheimer disease related 4-repeat tauopathies
    $643,670 · awarded Apr 1, 2026 · 5R01DC014942-09
  • DMITRIY YABLONSKIY — WASHINGTON UNIVERSITY, MO
    Deep-Learning-Augmented Quantitative Gradient Recalled Echo (DLA-qGRE) MRI for in vivo Clinical Evaluation of Brain Microstructural Neurodegeneration in Alzheimer Disease
    $661,985 · awarded Mar 3, 2026 · 4R01AG082030-02
Search more PIs in Alzheimer's disease →

CRISPR & gene editing

Therapeutic gene editing, base editing, and prime editing.

  • Changchun Liu — UNIVERSITY OF CONNECTICUT SCH OF MED/DNT, CT
    Asymmetric CRISPR Approach for Nucleic Acid Quantification
    $643,849 · awarded Mar 30, 2026 · 2R01EB023607-06A1
  • William Pu — BOSTON CHILDREN'S HOSPITAL, MA
    A modular system for murine CRISPR genome and epigenome editing
    $267,000 · awarded Mar 27, 2026 · 5R21OD037909-02
  • Naama Aviram — SLOAN-KETTERING INST CAN RESEARCH, NY
    Molecular mechanisms of memory formation and tolerance in CRISPR-Cas systems
    $249,000 · awarded Apr 2, 2026 · 5R00GM148720-04
  • Mats Ljungman — UNIVERSITY OF MICHIGAN AT ANN ARBOR, MI
    Precision targeting of bladder cancer using CRISPR
    $582,849 · awarded Feb 17, 2026 · 5R01CA285730-03
  • Shannon Miller — SCRIPPS RESEARCH INSTITUTE, THE, CA
    Development of potent and safe CRISPR tools for in vivo gene editing using directed evolution
    $230,000 · awarded May 5, 2026 · 5R21EB036298-03
Search more PIs in CRISPR & gene editing →

Cancer immunotherapy

Checkpoint inhibitors, CAR-T, TIL therapy, and beyond.

  • TERRY SHEPPARD — KEYSTONE SYMPOSIA, CO
    Cancer Immunotherapy: Basic Mechanisms Informing Clinical Applications & Combinations
    $5,000 · awarded Mar 3, 2026 · 1R13CA310704-01
  • Veronika Fedirko — UNIVERSITY OF TX MD ANDERSON CAN CTR, TX
    Gut Microbiome and Cancer Immunotherapy Outcomes in Advanced Renal Cell Carcinoma
    $927,329 · awarded Mar 3, 2026 · 5R01CA255322-05
  • Yuwen Zhu — UNIVERSITY OF COLORADO DENVER, CO
    The GPR171 pathway in cancer immunotherapy
    $355,706 · awarded Apr 2, 2026 · 5R01CA279398-04
  • ANDREW WIEMER — UNIVERSITY OF CONNECTICUT STORRS, CT
    Synthesis and evaluation of BTN3A1 ligands for cancer immunotherapy
    $374,171 · awarded May 1, 2026 · 5R01CA266138-05
  • Wei Hu — YALE UNIVERSITY, CT
    Novel Treg inactivating approach for cancer immunotherapy via targeted protein degradation
    $482,312 · awarded Apr 6, 2026 · 1R01CA295942-01A1
Search more PIs in Cancer immunotherapy →

GLP-1 & metabolic disease

Diabetes, obesity, and weight-loss therapeutic mechanisms.

  • ZHIPING PANG — RUTGERS BIOMEDICAL AND HEALTH SCIENCES, NJ
    Synaptic and circuit mechanisms of central GLP-1 signaling in energy balance
    $479,051 · awarded Apr 23, 2026 · 5R01DK131452-05
  • Madhusmita Misra — UNIVERSITY OF VIRGINIA, VA
    Bone metabolism in adolescents undergoing GLP-1 receptor agonist therapy
    $471,776 · awarded Apr 24, 2026 · 5R01HD118635-07
  • STEVEN SCHWENDEMAN — UNIVERSITY OF MICHIGAN AT ANN ARBOR, MI
    Remote Loading of Melanocortin and GLP-1 Peptides in Polymers for Treatment of Obesity
    $231,000 · awarded Apr 17, 2026 · 1R56DK141545-01A1
  • Jessica Barson — DREXEL UNIVERSITY, PA
    Suppression of ethanol dependence-induced maladaptive appetitive and consummatory behavior by the GLP-1 system
    $564,306 · awarded May 5, 2026 · 1R01AA031732-01A1
  • MICHAEL CAMILLERI — MAYO CLINIC ROCHESTER, MN
    A Randomized, placebo-controlled trial of the effects of Long-Acting GLP-1 or Dual Incretin (GLP-1 and GIP) Modulation on Gastrointestinal Functions and Relationship to Weight Loss
    $322,800 · awarded Apr 9, 2026 · 5R01DK142606-02
Search more PIs in GLP-1 & metabolic disease →

Long COVID

Post-acute sequelae and chronic infection-driven illness.

  • Alexei Tumanov — UNIVERSITY OF TEXAS HLTH SCIENCE CENTER, TX
    Lymphotoxin-dependent control of long COVID
    $234,715 · awarded Feb 13, 2026 · 1R21AI185790-01A1
  • Amal Amer — OHIO STATE UNIVERSITY, OH
    Role of the Non-canonical Inflammasome in SARS-CoV-2-mediated Pathology and Coagulopathy
    $2,974,582 · awarded Apr 21, 2026 · 5P01AI175399-03
  • Alba Azola — JOHNS HOPKINS UNIVERSITY, MD
    Blood-Brain Barrier Integrity and Immune Dynamics in Neuropsychiatric Sequelae of Post-SARS-CoV-2 onset ME/CFS versus Pre-Pandemic ME/CFS Patients
    $633,378 · awarded Apr 17, 2026 · 1R01NS147100-01
  • DANIELLE REED — MONELL CHEMICAL SENSES CENTER, PA
    Inflammation and chemosensory loss
    $2,654,249 · awarded Feb 26, 2026 · 1P50DC022549-01A1
  • Jarred Younger — UNIVERSITY OF ALABAMA AT BIRMINGHAM, AL
    Low-dose naltrexone (LDN) for the treatment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
    $556,686 · awarded Mar 6, 2026 · 1UG3NS141843-01A1
Search more PIs in Long COVID →