NIH PAR · NIAID · P01

PAR-27-082: NIAID Investigator Initiated Program Project Applications (P01 Clinical Trial Not Allowed)

Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards

Open for applicationsNext due date: Jan 25, 2027Expires May 26, 2029

This notice of funding opportunity (NOFO) invites submission of investigator-initiated Program Project (P01) applications. The proposed Programs should address scientific areas relevant to the NIAID mission including: biology and pathogenesis of infectious microbes, including HIV; host-microbe interactions; mechanisms regulating immune system development and function across the lifespan, and in response to infectious pathogens; immune dysfunction resulting in allergy, asthma, autoimmunity, immunodeficiency, or transplant rejection; and translational research to develop vaccines, therapeutics, and diagnostics to prevent and treat infectious and immune-mediated diseases. Each application…

Full NOFO in the NIH Guide Apply on Grants.gov

NOFO number
PAR-27-082
Type
PAR
Activity code
P01
Primary institute
NIAID · National Institute of Allergy and Infectious Diseases
Clinical trials
Not Allowed
Posted
May 7, 2026
Opens
Aug 25, 2026
Expires
May 26, 2029

PAR-27-082 due dates

8 application due dates remain before the NOFO expires. Dates marked * are NIH standard due dates. Check the related notices below for changes NIH made after posting.

Application due dates and review cycles for PAR-27-082
NewRenewal / Resubmission / Revision (as allowed)AIDS - New/Renewal/Resubmission/Revision, as allowedScientific Merit ReviewAdvisory Council ReviewEarliest Start Date
September 25, 2026 *September 25, 2026 *Not ApplicableMarch 2027May 2027July 2027
January 25, 2027 *January 25, 2027 *Not ApplicableJuly 2027October 2027February 2028
May 25, 2027 *May 25, 2027 *Not ApplicableNovember 2027January 2028March 2028
September 25, 2027 *September 25, 2027 *Not ApplicableMarch 2028May 2028July 2028
January 25, 2028 *January 25, 2028 *Not ApplicableJuly 2028October 2028February 2029
May 25, 2028 *May 25, 2028 *Not ApplicableNovember 2028January 2029March 2029
September 25, 2028 *September 25, 2028 *Not ApplicableMarch 2029May 2029July 2029
January 25, 2029 *January 25, 2029 *Not ApplicableJuly 2029October 2029February 2030
May 25, 2029 *May 25, 2029 *Not ApplicableNovember 2029January 2030March 2030

What its predecessor PAR-22-225 funded

PAR-27-082 reissues PAR-22-225. Until awards appear under the new number, its funding history is the best guide to who wins under this program: 45 projects and $227.2M in FY2022–FY2026.

Projects funded

45

Distinct projects, FY2022–FY2026

New awards

30

Type 1 (new project) award records

NIH funding

$227.2M

Award dollars under PAR-22-225, FY2022–FY2026

Funding by fiscal year

Award records, new awards, and funding by fiscal year under PAR-22-225
Fiscal yearAward recordsNew awardsFunding
FY202200$0
FY202300$0
FY20241311$35.3M
FY2025308$73.8M
FY20265011$118.1M

Institutions with the most funding

  1. Weill Medical Coll of Cornell Univ$27.8M · 4 projects
  2. Tufts University Boston$14.2M · 1 project
  3. Feinstein Institute for Medical Research$13.8M · 2 projects
  4. Columbia University Health Sciences$12.5M · 3 projects
  5. Brigham and Women's Hospital$12.1M · 3 projects
  6. Dana-Farber Cancer Inst$12.1M · 2 projects
  7. University of Minnesota$10.2M · 2 projects
  8. University of Pittsburgh at Pittsburgh$9.1M · 2 projects

Funding institutes

  • NIAID$227.2M · 93

Activity codes funded

Most recent new awards

FY2026 closed on September 30, 2026, but NIH keeps posting that year's awards to RePORTER for several weeks. FY2026 figures reflect records available on October 16, 2026 and may rise slightly at the next refresh.

Participating institutes

2 NIH institutes and offices take applications under PAR-27-082. Contact the program officer at the institute that fits your research before applying.

  • NIAID · National Institute of Allergy and Infectious Diseases
  • none

Related notices

NIH lists no related notices for PAR-27-082 yet.

Award terms

Application types allowed
New Renewal Resubmission Revision The OER Glossary and the How to Apply - Application Guide provides details on these application types. Only those application types listed here are allowed for this NOFO.
Award budget
Application budgets are not limited but need to reflect the actual needs of the proposed project.
Project period
The scope of the proposed project should determine the project period. The maximum project period is five years. NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO.
Funds available and number of awards
The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications.

Summarized from the NOFO text; the full NOFO governs eligibility, budget, and review.

Related NOFOs

  • Reissue of PAR-22-225.

Other open NOFOs for P01

Browse all open NIH NOFOs

About this page

GotGrant gathers the NOFO, its participation and change notices, and its NOSIs from the NIH Guide for Grants and Contracts, and counts funded projects from NIH RePORTER by the opportunity number each award was made under. Data refreshed October 16, 2026; the NIH Guide is the authoritative source. See our data methodology.

Find who wins under this NOFO

NIH grant searchLook up awards by topic, PI, or institution.Find funded PIsInvestigators with recent NIH awards in your research area.Institute fit by topicWhich NIH institutes and institutions lead a research area.Funding trendsYear-by-year NIH award totals for any keyword.