NIH RFA · NHGRI · UM1

RFA-HG-27-010: Computational Modeling and Analysis of the Impact of Genomic Variation on Function (UM1, Clinical Trial Not Allowed)

Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards

Opens Nov 14, 2026Next due date: Dec 14, 2026Expires Dec 15, 2026

The purpose of this Notice of Funding Opportunity (NOFO) is to solicit applications to develop, apply, and test predictive models and perform integrative analyses to determine the impact of genomic variation on genome function. Centers funded through this initiative will become a part of the Impact of Genomic Variation on Function (IGVF) Consortium. As consortium members, centers will work together to ensure all consortium resources are accessible to a wide variety of potential users. Centers also will collaborate with other consortium components to guide and optimize IGVF experimental design, to provide analytical expertise and support for consortium-wide efforts, and to develop and…

Full NOFO in the NIH Guide Apply on Grants.gov

NOFO number
RFA-HG-27-010
Type
RFA
Activity code
UM1
Primary institute
NHGRI · National Human Genome Research Institute
Clinical trials
Not Allowed
Posted
Oct 9, 2026
Opens
Nov 14, 2026
Expires
Dec 15, 2026

RFA-HG-27-010 due dates

1 application due date remains before the NOFO expires. Dates marked * are NIH standard due dates. Check the related notices below for changes NIH made after posting.

Application due dates and review cycles for RFA-HG-27-010
NewRenewal / Resubmission / Revision (as allowed)AIDS - New/Renewal/Resubmission/Revision, as allowedScientific Merit ReviewAdvisory Council ReviewEarliest Start Date
December 14, 2026Not ApplicableNot ApplicableJuly 2027August 2027September 2027

Funded projects

NIH RePORTER lists no awards under RFA-HG-27-010 in FY2022–FY2026, and it is a new NOFO rather than a reissue. Awards usually appear a few months after the first review cycle.

Participating institutes

2 NIH institutes and offices take applications under RFA-HG-27-010. Contact the program officer at the institute that fits your research before applying.

  • NHGRI · National Human Genome Research Institute
  • none

Related notices

NIH lists no related notices for RFA-HG-27-010 yet.

Award terms

Application types allowed
New The OER Glossary and the How to Apply - Application Guide provide details on these application types. Only those application types listed here are allowed for this NOFO.
Award budget
Application budgets are limited to 800,000 direct costs and need to reflect the actual needs of the proposed project.
Project period
The maximum project period is 5 years. NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO.
Funds available and number of awards
NHGRI intends to commit up to 5,000,000 in FY2027 to fund up to five awards.

Summarized from the NOFO text; the full NOFO governs eligibility, budget, and review.

Related NOFOs

Other open NOFOs for UM1

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About this page

GotGrant gathers the NOFO, its participation and change notices, and its NOSIs from the NIH Guide for Grants and Contracts, and counts funded projects from NIH RePORTER by the opportunity number each award was made under. Data refreshed October 16, 2026; the NIH Guide is the authoritative source. See our data methodology.

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