NIH PA · NIH · F31
PA-25-422: Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (Parent F31)
Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards
The purpose of the Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral (Parent F31) award is to enable promising predoctoral students will obtain individualized, mentored research training from outstanding faculty sponsors while conducting dissertation research projects in scientific health-related fields relevant to the missions of the participating NIH Institutes and Centers. The proposed mentored research training must reflect the candidates dissertation research project and is expected to clearly enhance the individuals potential to develop into a productive, independent research scientist. This Notice of Funding Opportunity (NOFO) does not allow candidates…
- NOFO number
- PA-25-422
- Type
- PA
- Activity code
- F31
- Primary institute
- NIH
- Clinical trials
- Not Allowed
- Posted
- Jun 12, 2025
- Opens
- Jul 8, 2025
- Expires
- May 8, 2028
PA-25-422 due dates
5 application due dates remain before the NOFO expires. Dates marked * are NIH standard due dates. Check the related notices below for changes NIH made after posting.
| Application Due Date(s) | Renewal / Resubmission / Revision (as allowed) | AIDS - New/Renewal/Resubmission/Revision, as allowed | Scientific Merit Review | Advisory Council Review | Earliest Start Date |
|---|---|---|---|---|---|
| August 08, 2025 | August 08, 2025 * | September 07, 2025 * | November 2025 | January 2026 | April 2026 |
| December 08, 2025 | December 08, 2025 * | January 07, 2026 * | March 2026 | May 2026 | July 2026 |
| April 08, 2026 | April 08, 2026 * | May 07, 2026 * | July 2026 | October 2026 | December 2026 |
| August 08, 2026 | August 08, 2026 * | Not Applicable | November 2026 | January 2027 | April 2027 |
| December 08, 2026 | December 08, 2026 * | Not Applicable | March 2027 | May 2027 | July 2027 |
| April 08, 2027 | April 08, 2027 * | Not Applicable | July 2027 | October 2027 | December 2027 |
| August 08, 2027 | August 08, 2027 * | Not Applicable | November 2027 | January 2028 | April 2028 |
| December 08, 2027 | December 08, 2027 * | Not Applicable | March 2028 | May 2028 | July 2028 |
| April 08, 2028 | April 08, 2028 * | Not Applicable | July 2028 | October 2028 | December 2028 |
Projects funded under PA-25-422
NIH RePORTER lists 584 projects funded under PA-25-422 in FY2022–FY2026, with $26.5M in award dollars. Counts include each project's later non-competing years, which keep the original NOFO number.
Projects funded
584
Distinct projects, FY2022–FY2026
New awards
584
Type 1 (new project) award records
NIH funding
$26.5M
Award dollars under PA-25-422, FY2022–FY2026
Funding by fiscal year
| Fiscal year | Award records | New awards | Funding |
|---|---|---|---|
| FY2022 | 0 | 0 | $0 |
| FY2023 | 0 | 0 | $0 |
| FY2024 | 0 | 0 | $0 |
| FY2025 | 0 | 0 | $0 |
| FY2026 | 584 | 584 | $26.5M |
Institutions with the most funding
- University of Pennsylvania$1.1M · 21 projects
- Univ of North Carolina Chapel Hill$1.0M · 24 projects
- University of Michigan at Ann Arbor$1.0M · 22 projects
- Yale University$910K · 19 projects
- Emory University$855K · 17 projects
- Duke University$676K · 15 projects
- Vanderbilt University$657K · 16 projects
- University of Colorado Denver$605K · 15 projects
Funding institutes
- NIAID$7.1M · 158
- NCI$3.5M · 77
- NIMH$2.3M · 52
- NINDS$2.0M · 44
- NICHD$1.9M · 41
- NIDA$1.4M · 30
- NHLBI$1.4M · 31
- NIDCD$1.2M · 28
Activity codes funded
- F31584 records
Most recent new awards
- Identification of causal DNA variants that influence gene expression in trans (opens NIH RePORTER)
University of Minnesota · 1F31HG015201-01 · NHGRI · Notice Sep 23, 2026
$50KF31
- Investigating the Role of Gustatory Cortical Dynamics in Foraging Behaviors (opens NIH RePORTER)
Brandeis University · 1F31DC024422-01 · NIDCD · Notice Sep 17, 2026
$36KF31
- Establishing the Mechanisms of Antiretroviral Induced Osteoporosis and Obesity (opens NIH RePORTER)
Rush University Medical Center · 1F31AR088599-01 · NIAMS · Notice Sep 17, 2026
$50KF31
- Development of Chemical Tools to Probe the Role of CHD1 in Viral Proliferation (opens NIH RePORTER)
Univ of North Carolina Chapel Hill · 1F31AI203122-01 · NIAID · Notice Sep 17, 2026
$41KF31
- Regulation of Cardiac Fibrosis by Substance P Receptors (opens NIH RePORTER)
West Virginia University · 1F31HL184786-01A1 · NHLBI · Notice Sep 17, 2026
$50KF31
- Molecular mechanisms and neural impact of human microglia immune tolerance (opens NIH RePORTER)
Baylor College of Medicine · 1F31EY039700-01 · NEI · Notice Sep 17, 2026
$50KF31
What its predecessor PA-23-272 funded
PA-25-422 reissues PA-23-272. Its funding history is the best guide to who wins under this program: 1,414 projects and $106.9M in FY2022–FY2026.
Projects funded
1,414
Distinct projects, FY2022–FY2026
New awards
1,414
Type 1 (new project) award records
NIH funding
$106.9M
Award dollars under PA-23-272, FY2022–FY2026
Funding by fiscal year
| Fiscal year | Award records | New awards | Funding |
|---|---|---|---|
| FY2022 | 0 | 0 | $0 |
| FY2023 | 0 | 0 | $0 |
| FY2024 | 335 | 335 | $14.4M |
| FY2025 | 1,025 | 770 | $44.6M |
| FY2026 | 1,077 | 309 | $47.9M |
Institutions with the most funding
- University of Pennsylvania$5.4M · 63 projects
- Johns Hopkins University$3.7M · 44 projects
- University of Michigan at Ann Arbor$3.6M · 49 projects
- Emory University$3.6M · 41 projects
- Yale University$3.1M · 42 projects
- Univ of North Carolina Chapel Hill$3.0M · 37 projects
- Vanderbilt University$2.7M · 41 projects
- University of Pittsburgh at Pittsburgh$2.5M · 29 projects
Funding institutes
- NIAID$15.6M · 357
- NHLBI$14.2M · 324
- NINDS$13.8M · 316
- NCI$11.9M · 271
- NICHD$7.9M · 176
- NIMH$7.2M · 164
- NIDDK$6.9M · 157
- NIA$4.8M · 109
Activity codes funded
- F312,437 records
Most recent new awards
- The role of astrocytes in TRN dysfunction and sleep disruption in Alzheimer's disease (opens NIH RePORTER)
Baylor College of Medicine · 1F31AG091930-01A1 · NIA · Notice Sep 14, 2026
$50KF31
- Unraveling microglia-intrinsic sex-specific properties and their contribution to Alzheimer's disease pathology (opens NIH RePORTER)
University of Rochester · 1F31AG099644-01 · NIA · Notice Sep 14, 2026
$50KF31
- Evaluating the Contribution of Care Pathways and Clinical Features To Home Health Quality Outcomes for People with Dementia (opens NIH RePORTER)
Medical University of South Carolina · 1F31AG099736-01 · NIA · Notice Sep 2, 2026
$46KF31
- Impact of platelet-monocyte interactions on HIV-associated vascular disease (opens NIH RePORTER)
University of Rochester · 1F31AG099733-01 · NIA · Notice Aug 21, 2026
$50KF31
- Investigating sexually dimorphic regulation of histone H3K9 methylation in heat-induced male infertility (opens NIH RePORTER)
University of Oregon · 1F31HD121368-01 · NICHD · Notice Aug 20, 2026
$50KF31
- Unveiling Selective Vulnerability to Alzheimer's Disease in an Aging Population (opens NIH RePORTER)
University of California-Irvine · 1F31AG099684-01 · NIA · Notice Aug 18, 2026
$48KF31
FY2026 closed on September 30, 2026, but NIH keeps posting that year's awards to RePORTER for several weeks. FY2026 figures reflect records available on October 16, 2026 and may rise slightly at the next refresh.
Participating institutes
24 NIH institutes and offices take applications under PA-25-422. Contact the program officer at the institute that fits your research before applying.
- NIH
- NEI · National Eye Institute
- NHLBI · National Heart, Lung, and Blood Institute
- NHGRI · National Human Genome Research Institute
- NIA · National Institute on Aging
- NIAAA · National Institute on Alcohol Abuse and Alcoholism
- NIAID · National Institute of Allergy and Infectious Diseases
- NIAMS · National Institute of Arthritis and Musculoskeletal and Skin Diseases
- NIBIB · National Institute of Biomedical Imaging and Bioengineering
- NICHD · Eunice Kennedy Shriver National Institute of Child Health and Human Development
- NIDCD · National Institute on Deafness and Other Communication Disorders
- NIDCR · National Institute of Dental and Craniofacial Research
- NIDDK · National Institute of Diabetes and Digestive and Kidney Diseases
- NIDA · National Institute on Drug Abuse
- NIEHS · National Institute of Environmental Health Sciences
- NINDS · National Institute of Neurological Disorders and Stroke
- NINR · National Institute of Nursing Research
- NIMHD · National Institute on Minority Health and Health Disparities
- NLM · National Library of Medicine
- NCCIH · National Center for Complementary and Integrative Health
- NCI · National Cancer Institute
- NIMH · National Institute of Mental Health
- NIGMS · National Institute of General Medical Sciences
- ODSS
Related notices
Mar 19, 2026 · NOT-GM-26-002
Notice of NIGMS Participation in PA-25-422 Ruth L. Kirschstein National Research Service Award NRSA) Individual Predoctoral Fellowship Parent F31)".
Nov 24, 2025 · NOT-DE-26-013
Notice of Rescheduled NIDCR Pre-Application and Technical Assistance Webinars on Applying for Fellowship F) Awards and Career Development K) Awards.
Sep 25, 2025 · NOT-DE-26-012
Notice of NIDCR Pre-Application and Technical Assistance Webinars on Applying for Fellowship F) Awards and Career Development K) Awards.
Jun 18, 2025 · NOT-MH-25-215
Notice of NIMH Participation in PA-25-422, Ruth L. Kirschstein National Research Service Award NRSA) Individual Predoctoral Fellowship Parent F31).
Jun 17, 2025 · NOT-OD-25-126
NOTICE OF CORRECTION: Eligible Individuals, Ruth L. Kirschstein Research Service Award NRSA) Fellowships.
Aug 31, 2022 · NOT-OD-22-198
Implementation Changes for Genomic Data Sharing Plans Included with Applications Due on or after January 25, 2023. See Notice NOT-OD-22-198.
Aug 5, 2022 · NOT-OD-22-189
Implementation Details for the NIH Data Management and Sharing Policy. See Notice NOT-OD-22-189.
Notices of Special Interest (NOSIs)
NIH has attached 17 NOSIs to PA-25-422; none are active now. A NOSI flags a topic an institute wants to fund through this NOFO.
Award terms
- Application types allowed
- NewRenewal - Individual fellowship awards are generally not renewable. In rare cases in which fellowship awardees require further fellowship support, they should consult with NIH staff to obtain advice regarding submission of a renewal applicationResubmission The OER Glossary and the How to Apply - Application Guide provide details on these application types. Only those application types listed…
- Award budget
- Information
- Project period
- Individuals may receive up to 5 years of aggregate Kirschstein-NRSA support at the predoctoral level up to 6 years for dual degree training, e.g., MD/PhD), and up to 3 years of aggregate Kirschstein-NRSA support at the postdoctoral level, including any combination of support from institutional training grants e.g., T32) and an individual fellowship award. Other
- Funds available and number of awards
- The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications.
Summarized from the NOFO text; the full NOFO governs eligibility, budget, and review.
Related NOFOs
- Reissue of PA-23-272.
About this page
GotGrant gathers the NOFO, its participation and change notices, and its NOSIs from the NIH Guide for Grants and Contracts, and counts funded projects from NIH RePORTER by the opportunity number each award was made under. Data refreshed October 16, 2026; the NIH Guide is the authoritative source. See our data methodology.