NIH PAR · NHGRI · R01

PAR-25-371: Ethical, Legal and Social Implications (ELSI) Research (R01 Clinical Trial Optional)

Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards

Open for applicationsNext due date: Oct 20, 2026Expires Nov 19, 2026

The purpose of this NOFO is to invite Research Project (R01) applications that propose to study the ethical, legal, and social implications (ELSI) of human genetics and genomics. Applications may propose studies using either single or mixed methods. Approaches may include but are not limited to empirical qualitative and quantitative methods, as well as conceptual, legal, and normative analyses. Direct involvement of key stakeholders where appropriate is encouraged. This Notice of Funding Opportunity (NOFO) requires a Plan for Enhancing Diverse Perspectives (PEDP) as part of the application. Applications without a PEDP will not be reviewed.

Full NOFO in the NIH Guide Apply on Grants.gov

NOFO number
PAR-25-371
Type
PAR
Activity code
R01
Primary institute
NHGRI · National Human Genome Research Institute
Clinical trials
Optional
Posted
Jan 13, 2025
Opens
Jan 20, 2025
Expires
Nov 19, 2026

PAR-25-371 due dates

1 application due date remains before the NOFO expires. Dates marked * are NIH standard due dates. Check the related notices below for changes NIH made after posting.

Application due dates and review cycles for PAR-25-371
Application Due Date(s)Renewal / Resubmission / Revision (as allowed)AIDS - New/Renewal/Resubmission/Revision, as allowedScientific Merit ReviewAdvisory Council ReviewEarliest Start Date
February 20, 2025March 19, 2025Not ApplicableJuly 2025October 2025December 2025
June 17, 2025July 18, 2025Not ApplicableNovember 2025January 2026April 2026
October 20, 2025November 18, 2025Not ApplicableMarch 2026May 2026July 2026
February 19, 2026March 18, 2026Not ApplicableJuly 2026October 2026December 2026
June 18, 2026July 20, 2026Not ApplicableNovember 2026January 2027April 2027
October 20, 2026November 18, 2026Not ApplicableMarch 2027May 2027July 2027

Projects funded under PAR-25-371

NIH RePORTER lists 8 projects funded under PAR-25-371 in FY2022–FY2026, with $7.8M in award dollars. Counts include each project's later non-competing years, which keep the original NOFO number.

Projects funded

8

Distinct projects, FY2022–FY2026

New awards

8

Type 1 (new project) award records

NIH funding

$7.8M

Award dollars under PAR-25-371, FY2022–FY2026

Funding by fiscal year

Award records, new awards, and funding by fiscal year under PAR-25-371
Fiscal yearAward recordsNew awardsFunding
FY202200$0
FY202300$0
FY202400$0
FY202500$0
FY202688$7.8M

Institutions with the most funding

  1. New York University School of Medicine$2.7M · 1 project
  2. University of Connecticut Sch of Med/Dnt$849K · 1 project
  3. University of California, San Francisco$842K · 1 project
  4. Boston Children's Hospital$823K · 1 project
  5. Massachusetts General Hospital$769K · 1 project
  6. Harvard Pilgrim Health Care, Inc.$763K · 1 project
  7. Stanford University$546K · 1 project
  8. Children's Mercy Hosp (Kansas City, Mo)$465K · 1 project

Funding institutes

  • NHGRI$4.1M · 3
  • NICHD$2.9M · 4
  • NIDA$769K · 1

Activity codes funded

Most recent new awards

What its predecessor PAR-23-293 funded

PAR-25-371 reissues PAR-23-293. Its funding history is the best guide to who wins under this program: 6 projects and $12.6M in FY2022–FY2026.

Projects funded

6

Distinct projects, FY2022–FY2026

New awards

5

Type 1 (new project) award records

NIH funding

$12.6M

Award dollars under PAR-23-293, FY2022–FY2026

Funding by fiscal year

Award records, new awards, and funding by fiscal year under PAR-23-293
Fiscal yearAward recordsNew awardsFunding
FY202200$0
FY202300$0
FY202400$0
FY202554$8.7M
FY202641$3.9M

Institutions with the most funding

  1. Feinstein Institute for Medical Research$3.3M · 1 project
  2. Seattle Children's Hospital$3.3M · 1 project
  3. University of Washington$2.3M · 1 project
  4. Columbia University Health Sciences$1.7M · 1 project
  5. UT Southwestern Medical Center$1.1M · 1 project
  6. Stanford University$927K · 1 project

Funding institutes

  • NHGRI$11.5M · 7
  • NCI$1.1M · 2

Activity codes funded

Most recent new awards

FY2026 closed on September 30, 2026, but NIH keeps posting that year's awards to RePORTER for several weeks. FY2026 figures reflect records available on October 16, 2026 and may rise slightly at the next refresh.

Participating institutes

14 NIH institutes and offices take applications under PAR-25-371. Contact the program officer at the institute that fits your research before applying.

  • NHGRI · National Human Genome Research Institute
  • NEI · National Eye Institute
  • NIAID · National Institute of Allergy and Infectious Diseases
  • NICHD · Eunice Kennedy Shriver National Institute of Child Health and Human Development
  • NIDCD · National Institute on Deafness and Other Communication Disorders
  • NIDA · National Institute on Drug Abuse
  • NIEHS · National Institute of Environmental Health Sciences
  • NIMH · National Institute of Mental Health
  • NINDS · National Institute of Neurological Disorders and Stroke
  • NIMHD · National Institute on Minority Health and Health Disparities
  • NCI · National Cancer Institute
  • THRO
  • OBSSR
  • ORWH

Related notices

  1. Nov 13, 2023 · NOT-HG-24-010

    Notice of Pre-Application Webinar for Ethical, Legal and Social Implications ELSI) Research: PAR-23-293 R01 Clinical Trial Optional), PAR-23-294 R21 Clinical Trial Optional) and PAR-23-295 R03 Clinical Trial Optional).

  2. Aug 31, 2022 · NOT-OD-22-198

    Implementation Changes for Genomic Data Sharing Plans Included with Applications Due on or after January 25, 2023. See Notice NOT-OD-22-198.

  3. Aug 5, 2022 · NOT-OD-22-189

    Implementation Details for the NIH Data Management and Sharing Policy. See Notice NOT-OD-22-189.

Award terms

Application types allowed
NewRenewalResubmissionRevision The OER Glossary and the How to Apply Application Guide provide details on these application types. Only those application types listed here are allowed for this NOFO.
Award budget
Application budgets are not limited but need to reflect the actual needs of the proposed project.Budgets should include costs required to implement the proposed Data Management and Sharing Plan and the proposed Resource Sharing Plan
Project period
The scope of the proposed project should determine the project period. The maximum project period is 5 years, but given how quickly the field changes, it is expected that some projects will be no more than 4 years in duration. Longer project periods should be well justified. Additional consideration for longer projects may be given to new or early stage investigators or projects proposing…
Funds available and number of awards
The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications.

Summarized from the NOFO text; the full NOFO governs eligibility, budget, and review.

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About this page

GotGrant gathers the NOFO, its participation and change notices, and its NOSIs from the NIH Guide for Grants and Contracts, and counts funded projects from NIH RePORTER by the opportunity number each award was made under. Data refreshed October 16, 2026; the NIH Guide is the authoritative source. See our data methodology.

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