NIH PAR · NIDA · U01
PAR-24-269: NIDA Animal Genomics Program (U01 Clinical Trial Not Allowed)
Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards
The purpose of the NIDA Animal Genetics Program is to identify genetic, genomic, and molecular (epi)genetic variants that underlie: 1. Phenotypes associated with addictive behaviors and/or vulnerability to distinct stages along the substance use disorders (SUD) trajectory (e.g. initial/acute use, escalation of use, acquisition of tolerance, dependence, uncontrolled use, abstinence and relapse or recovery); 2. Behaviors associated with SUD (e.g. impulsivity, novelty seeking, delayed discounting, and other genetically-associated phenotypes); and 3. Comorbidities that demonstrate genetic correlations with phenotypes and behaviors linked with SUD (e.g. anxiety, stress, poor maternal care,…
- NOFO number
- PAR-24-269
- Type
- PAR
- Activity code
- U01
- Primary institute
- NIDA · National Institute on Drug Abuse
- Clinical trials
- Not Allowed
- Posted
- Aug 13, 2024
- Opens
- Jan 11, 2025
- Expires
- Feb 12, 2027
PAR-24-269 due dates
No application due dates remain in the listed cycles. Dates marked * are NIH standard due dates. Check the related notices below for changes NIH made after posting.
| Letter of Intent Due Date(s) |
|---|
| January 11, 2025 |
| February 11, 2025 |
| February 11, 2025 |
| Not Applicable |
| June 2025 |
| October 2025 |
| December 2025 |
| July 23, 2025 |
| July 23, 2025 |
| Not Applicable |
| November 2025 |
| January 2026 |
| April 2026 |
| February 11, 2026 |
| February 11, 2026 |
| Not Applicable |
| June 2026 |
| October 2026 |
| December 2026 |
| July 23, 2026 |
| July 23, 2026 |
| Not Applicable |
| November 2026 |
| January 2027 |
Projects funded under PAR-24-269
NIH RePORTER lists 2 projects funded under PAR-24-269 in FY2022–FY2026, with $1.7M in award dollars. Counts include each project's later non-competing years, which keep the original NOFO number.
Projects funded
2
Distinct projects, FY2022–FY2026
New awards
1
Type 1 (new project) award records
NIH funding
$1.7M
Award dollars under PAR-24-269, FY2022–FY2026
Funding by fiscal year
| Fiscal year | Award records | New awards | Funding |
|---|---|---|---|
| FY2022 | 0 | 0 | $0 |
| FY2023 | 0 | 0 | $0 |
| FY2024 | 0 | 0 | $0 |
| FY2025 | 0 | 0 | $0 |
| FY2026 | 2 | 1 | $1.7M |
Institutions with the most funding
- University of California, San Diego$900K · 1 project
- Jackson Laboratory$805K · 1 project
Funding institutes
- NIDA$1.7M · 2
Activity codes funded
- U012 records
Most recent new awards
- Genetic and Microbiome Control of Addiction-like Behaviors in Mice (opens NIH RePORTER)
Jackson Laboratory · 1U01DA064597-01 · NIDA · Notice Jun 3, 2026
$805KU01
What its predecessor PAR-21-244 funded
PAR-24-269 reissues PAR-21-244. Its funding history is the best guide to who wins under this program: 9 projects and $25.6M in FY2022–FY2026.
Projects funded
9
Distinct projects, FY2022–FY2026
New awards
5
Type 1 (new project) award records
NIH funding
$25.6M
Award dollars under PAR-21-244, FY2022–FY2026
Funding by fiscal year
| Fiscal year | Award records | New awards | Funding |
|---|---|---|---|
| FY2022 | 1 | 0 | $710K |
| FY2023 | 5 | 2 | $4.2M |
| FY2024 | 6 | 1 | $5.0M |
| FY2025 | 10 | 2 | $8.0M |
| FY2026 | 9 | 0 | $7.7M |
Institutions with the most funding
- University of California, San Diego$9.6M · 3 projects
- Loma Linda University$4.4M · 1 project
- University of Michigan at Ann Arbor$3.3M · 1 project
- University of Tennessee Health Sci Ctr$2.8M · 1 project
- University of California Los Angeles$2.1M · 1 project
- Seattle Children's Hospital$1.8M · 1 project
- State University of New York at Buffalo$1.6M · 1 project
Funding institutes
- NIDA$25.6M · 31
Activity codes funded
- U0131 records
Most recent new awards
- Genetic substrates of cue-reactivity and cocaine motivation (opens NIH RePORTER)
State University of New York at Buffalo · 1U01DA060669-01A1 · NIDA · Notice Jul 28, 2025
$803KU01
- Deep Analysis of Transcriptome to Understand the Genetics of Substance Use Disorders in Rats (opens NIH RePORTER)
Seattle Children's Hospital · 1U01DA060443-01A1 · NIDA · Notice Jun 27, 2025
$945KU01
- Integrating genetic and circuit variation to identify genes involved in behaviors related to substance use disorder (opens NIH RePORTER)
University of California Los Angeles · 1U01DA059695-01 · NIDA · Notice Sep 13, 2024
$694KU01
- Pangenomics of nicotine abuse in the hybrid rat diversity panel (opens NIH RePORTER)
University of Tennessee Health Sci Ctr · 1U01DA057530-01 · NIDA · Notice Aug 29, 2023
$693KU01
- Genomic and Epigenomic Mechanisms of Maternal E-Cigarette induced Abnormal Brain Development (opens NIH RePORTER)
Loma Linda University · 1U01DA058278-01 · NIDA · Notice Apr 10, 2023
$997KU01
FY2026 closed on September 30, 2026, but NIH keeps posting that year's awards to RePORTER for several weeks. FY2026 figures reflect records available on October 16, 2026 and may rise slightly at the next refresh.
Participating institutes
2 NIH institutes and offices take applications under PAR-24-269. Contact the program officer at the institute that fits your research before applying.
- NIDA · National Institute on Drug Abuse
- none
Related notices
Mar 31, 2025 · NOT-OD-24-084
This funding opportunity was updated to align with agency priorities. Carefully reread the full funding opportunity and make any needed adjustments to your application prior to submission.April 4, 2024 - Overview of Grant Application and Review Changes for Due Dates on or after January 25,…
Aug 31, 2022 · NOT-OD-22-198
Implementation Changes for Genomic Data Sharing Plans Included with Applications Due on or after January 25, 2023. See Notice NOT-OD-22-198.
Aug 5, 2022 · NOT-OD-22-189
Implementation Details for the NIH Data Management and Sharing Policy.
Award terms
- Application types allowed
- NewRenewalResubmissionRevision The OER Glossary and the How to Apply Application Guide provide details on these application types. Only those application types listed here are allowed for this NOFO.
- Award budget
- Application budgets are not limited but need to reflect the actual needs of the proposed project.
- Project period
- The maximum project period is 5 years. NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO.
- Funds available and number of awards
- The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications.
Summarized from the NOFO text; the full NOFO governs eligibility, budget, and review.
Related NOFOs
- Reissue of PAR-21-244.
Other open NOFOs for U01
- RFA-DA-28-013Neural Ensembles & Used Substances (NExUS) Collaboratory: Building a Multimodal Inventory of Cell Ensembles Encoding the Effects of Addictive Substances (U01 Clinical Trial Not Allowed)NIDA · next due Feb 8, 2027
- RFA-AI-27-014Development of Candidate Medical Countermeasures (MCMs) and Technologies Against Radiological/Nuclear or Chemical Threats (U01 Clinical Trial Not Allowed)NIAID · next due Nov 9, 2026
- RFA-NS-27-015BRAIN Initiative Connectivity across Scales (BRAIN CONNECTS): Specialized Projects for Scalable Technologies (U01 Clinical Trial Not Allowed)NINDS · next due Feb 8, 2027
- RFA-MH-26-140BRAIN Initiative: Brain Behavior Quantification and Synchronization- Next Generation Sensor Technology Development (U01 Clinical Trial Optional)NIMH · next due Jun 15, 2027
- RFA-CA-27-019Early-Stage Development of Informatics Technologies for Cancer Research and Management (U01 Clinical Trial Optional)NCI · next due Oct 19, 2026
- RFA-DE-27-001Community Engagement Evaluation and Data Coordination (CEED) Hub to Advance Data and Practice Transformation for Optimizing Oral Health for All (U01, Clinical Trial Not Allowed)NIDCR · next due Oct 19, 2026
About this page
GotGrant gathers the NOFO, its participation and change notices, and its NOSIs from the NIH Guide for Grants and Contracts, and counts funded projects from NIH RePORTER by the opportunity number each award was made under. Data refreshed October 16, 2026; the NIH Guide is the authoritative source. See our data methodology.