NIH PA · NIH · R03

PA-25-302: NIH Small Research Grant Program (Parent R03 Clinical Trial Not Allowed)

Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards

Open for applicationsNext due date: Oct 16, 2026Expires Jan 8, 2028

The NIH Small Research Grant Program supports small research projects that can be carried out in a short period of time with limited resources. This program supports different types of projects including pilot and feasibility studies; secondary analysis of existing data; small, self-contained research projects; development of research methodology; and development of new research technology. This Notice of Funding Opportunity does not accept applications proposing clinical trial(s).

Full NOFO in the NIH Guide Apply on Grants.gov

NOFO number
PA-25-302
Type
PA
Activity code
R03
Primary institute
NIH
Clinical trials
Not Allowed
Posted
Dec 18, 2024
Opens
Jan 16, 2025
Expires
Jan 8, 2028

PA-25-302 due dates

4 application due dates remain before the NOFO expires. Dates marked * are NIH standard due dates. Check the related notices below for changes NIH made after posting.

Application due dates and review cycles for PA-25-302
Application Due Date(s)Renewal / Resubmission / Revision (as allowed)AIDS - New/Renewal/Resubmission/Revision, as allowedScientific Merit ReviewAdvisory Council ReviewEarliest Start Date
February 16, 2025March 16, 2025 *May 07, 2025 *July 2025October 2025December 2025
June 16, 2025July 16, 2025 *September 07, 2025 *November 2025January 2026April 2026
October 16, 2025November 16, 2025 *January 07, 2026 *March 2026May 2026July 2026
February 16, 2026March 16, 2026 *May 07, 2026 *July 2026October 2026December 2026
June 16, 2026July 16, 2026 *Not ApplicableNovember 2026January 2027April 2027
October 16, 2026November 16, 2026 *Not ApplicableMarch 2027May 2027July 2027
February 16, 2027March 16, 2027 *Not ApplicableJuly 2027October 2027December 2027
June 16, 2027July 16, 2027 *Not ApplicableNovember 2027January 2028April 2028
October 16, 2027November 16, 2027 *Not ApplicableMarch 2028May 2028July 2028

Projects funded under PA-25-302

NIH RePORTER lists 130 projects funded under PA-25-302 in FY2022–FY2026, with $16.7M in award dollars. Counts include each project's later non-competing years, which keep the original NOFO number.

Projects funded

130

Distinct projects, FY2022–FY2026

New awards

130

Type 1 (new project) award records

NIH funding

$16.7M

Award dollars under PA-25-302, FY2022–FY2026

Funding by fiscal year

Award records, new awards, and funding by fiscal year under PA-25-302
Fiscal yearAward recordsNew awardsFunding
FY202200$0
FY202300$0
FY202400$0
FY202511$157K
FY2026130129$16.5M

Institutions with the most funding

  1. Albany Medical College$328K · 2 projects
  2. Baylor College of Medicine$321K · 2 projects
  3. Duke University$317K · 3 projects
  4. Emory University$313K · 2 projects

Funding institutes

  • NIAID$5.0M · 45
  • NINDS$3.4M · 26
  • NICHD$2.8M · 18
  • NIBIB$1.4M · 15
  • NIA$1.3M · 9
  • NIEHS$1.0M · 7
  • NIMH$820K · 5
  • NIDA$318K · 2

Activity codes funded

What its predecessor PA-20-200 funded

PA-25-302 reissues PA-20-200. Its funding history is the best guide to who wins under this program: 725 projects and $105.2M in FY2022–FY2026.

Projects funded

725

Distinct projects, FY2022–FY2026

New awards

642

Type 1 (new project) award records

NIH funding

$105.2M

Award dollars under PA-20-200, FY2022–FY2026

Funding by fiscal year

Award records, new awards, and funding by fiscal year under PA-20-200
Fiscal yearAward recordsNew awardsFunding
FY2022256175$21.7M
FY2023331184$30.0M
FY2024272146$26.0M
FY2025221131$22.0M
FY2026666$5.5M

Institutions with the most funding

  1. Johns Hopkins University$2.2M · 14 projects
  2. Baylor College of Medicine$1.9M · 13 projects
  3. Ohio State University$1.7M · 11 projects
  4. Northwestern University$1.5M · 12 projects

Funding institutes

  • NIAID$28.9M · 351
  • NICHD$23.3M · 217
  • NINDS$13.3M · 137
  • NIBIB$10.1M · 124
  • NIA$9.4M · 96
  • NIMH$7.0M · 78
  • NIEHS$5.7M · 59
  • NIDA$4.3M · 50

Activity codes funded

  • R031,144 records
  • U3R2 records

FY2026 closed on September 30, 2026, but NIH keeps posting that year's awards to RePORTER for several weeks. FY2026 figures reflect records available on October 16, 2026 and may rise slightly at the next refresh.

Participating institutes

15 NIH institutes and offices take applications under PA-25-302. Contact the program officer at the institute that fits your research before applying.

  • NIH
  • NHGRI · National Human Genome Research Institute
  • NIA · National Institute on Aging
  • NIAAA · National Institute on Alcohol Abuse and Alcoholism
  • NIAID · National Institute of Allergy and Infectious Diseases
  • NIBIB · National Institute of Biomedical Imaging and Bioengineering
  • NICHD · Eunice Kennedy Shriver National Institute of Child Health and Human Development
  • NIDA · National Institute on Drug Abuse
  • NIEHS · National Institute of Environmental Health Sciences
  • NIMH · National Institute of Mental Health
  • NINDS · National Institute of Neurological Disorders and Stroke
  • NLM · National Library of Medicine
  • NCI · National Cancer Institute
  • NCATS · National Center for Advancing Translational Sciences
  • ODSS

Related notices

  1. Jul 16, 2026 · NOT-TR-26-011

    Notice of NCATS Participation in Notice of Funding Opportunity NOFO) PA-25-302 NIH Small Research Grant Program Parent R03 Clinical Trial Not Allowed).

  2. Jan 28, 2026 · NOT-OD-26-029

    NIH Removing AIDS Application Due Dates from NOFOs.

  3. Feb 10, 2026 · NOT-CA-26-003

    Notice of NCI's Participation in PA-25-302, NIH Small Research Grant Program Parent R03 Clinical Trial Not Allowed).

  4. Mar 31, 2025 · NOT-OD-24-084

    This funding opportunity was updated to align with agency priorities. Carefully reread the full funding opportunity and make any needed adjustments to your application prior to submission.April 4, 2024 - Overview of Grant Application and Review Changes for Due Dates on or after January 25,…

  5. Aug 31, 2022 · NOT-OD-22-198

    Implementation Changes for Genomic Data Sharing Plans Included with Applications Due on or after January 25, 2023. See Notice NOT-OD-22-198.

  6. Aug 5, 2022 · NOT-OD-22-189

    Implementation Details for the NIH Data Management and Sharing Policy. See Notice NOT-OD-22-189.

Notices of Special Interest (NOSIs)

NIH has attached 58 NOSIs to PA-25-302; none are active now. A NOSI flags a topic an institute wants to fund through this NOFO.

Award terms

Application types allowed
NewResubmissionRevision The OER Glossary and the How to Apply Application Guide provide details on these application types. Only those application types listed here are allowed for this NOFO.
Award budget
Application budgets are limited to 50,000 in direct costs per year.
Project period
The total project period may not exceed two years. NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO.
Funds available and number of awards
The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications..

Summarized from the NOFO text; the full NOFO governs eligibility, budget, and review.

Related NOFOs

  • Reissue of PA-20-200.

Other open NOFOs for R03

Browse all open NIH NOFOs

About this page

GotGrant gathers the NOFO, its participation and change notices, and its NOSIs from the NIH Guide for Grants and Contracts, and counts funded projects from NIH RePORTER by the opportunity number each award was made under. Data refreshed October 16, 2026; the NIH Guide is the authoritative source. See our data methodology.

Find who wins under this NOFO