NIH PAR · NIDDK · R03

PAR-25-091: Limited Competition: Small Grant Program for NIDDK K01/K08/K23/K25 Recipients (R03 Clinical Trial Optional)

Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards

Open for applicationsNext due date: Oct 16, 2026Expires Jan 8, 2028

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) announces a program that provides NIDDK-supported K01, K08, K23, and K25 recipients the opportunity to apply for Small Grant (R03) support at some point during the latter years of their award period of their K award. Through the use of this mechanism, the NIDDK is seeking to enhance the capability of its K01, K08, K23, and K25 award recipients to conduct research as they complete their transition to fully independent investigator status. The R03 grant mechanism supports different types of projects, including pilot and feasibility studies; secondary analysis of existing data; small, self-contained research projects;…

Full NOFO in the NIH Guide Apply on Grants.gov

NOFO number
PAR-25-091
Type
PAR
Activity code
R03
Primary institute
NIDDK · National Institute of Diabetes and Digestive and Kidney Diseases
Clinical trials
Optional
Posted
Jan 10, 2025
Opens
Jan 16, 2025
Expires
Jan 8, 2028

PAR-25-091 due dates

4 application due dates remain before the NOFO expires. Dates marked * are NIH standard due dates. Check the related notices below for changes NIH made after posting.

Application due dates and review cycles for PAR-25-091
Application Due Date(s)Renewal / Resubmission / Revision (as allowed)AIDS - New/Renewal/Resubmission/Revision, as allowedScientific Merit ReviewAdvisory Council ReviewEarliest Start Date
February 16, 2025March 16, 2025 *May 07, 2025 *July 2025October 2025December 2025
June 16, 2025July 16, 2025 *September 07, 2025 *November 2025January 2026April 2026
October 16, 2025November 16, 2025 *January 07, 2026 *March 2026May 2026July 2026
February 16, 2026March 16, 2026 *May 07, 2026 *July 2026October 2026December 2026
June 16, 2026July 16, 2026 *Not ApplicableNovember 2026January 2027April 2027
October 16, 2026November 16, 2026 *Not ApplicableMarch 2027May 2027July 2027
February 16, 2027March 16, 2027 *Not ApplicableJuly 2027October 2027December 2027
June 16, 2027July 16, 2027 *Not ApplicableNovember 2027January 2028April 2028
October 16, 2027November 16, 2027 *Not ApplicableMarch 2028May 2028July 2028

Projects funded under PAR-25-091

NIH RePORTER lists 36 projects funded under PAR-25-091 in FY2022–FY2026, with $4.5M in award dollars. Counts include each project's later non-competing years, which keep the original NOFO number.

Projects funded

36

Distinct projects, FY2022–FY2026

New awards

36

Type 1 (new project) award records

NIH funding

$4.5M

Award dollars under PAR-25-091, FY2022–FY2026

Funding by fiscal year

Award records, new awards, and funding by fiscal year under PAR-25-091
Fiscal yearAward recordsNew awardsFunding
FY202200$0
FY202300$0
FY202400$0
FY202500$0
FY20263636$4.5M

Institutions with the most funding

  1. Children's Hosp of Philadelphia$267K · 2 projects
  2. Boston Children's Hospital$267K · 2 projects
  3. Massachusetts General Hospital$248K · 2 projects
  4. Columbia University Health Sciences$247K · 2 projects
  5. Baylor College of Medicine$240K · 2 projects
  6. Vanderbilt University Medical Center$158K · 1 project
  7. Adventhealth Orlando$152K · 1 project
  8. Tufts Medical Center$134K · 1 project

Funding institutes

  • NIDDK$4.5M · 36

Activity codes funded

Most recent new awards

What its predecessor PAR-22-129 funded

PAR-25-091 reissues PAR-22-129. Its funding history is the best guide to who wins under this program: 72 projects and $16.6M in FY2022–FY2026.

Projects funded

72

Distinct projects, FY2022–FY2026

New awards

71

Type 1 (new project) award records

NIH funding

$16.6M

Award dollars under PAR-22-129, FY2022–FY2026

Funding by fiscal year

Award records, new awards, and funding by fiscal year under PAR-22-129
Fiscal yearAward recordsNew awardsFunding
FY202200$0
FY202365$1.1M
FY20243030$3.5M
FY20256536$10.9M
FY202690$1.1M

Institutions with the most funding

  1. University of Michigan at Ann Arbor$1.4M · 6 projects
  2. Indiana University Indianapolis$958K · 4 projects
  3. Columbia University Health Sciences$601K · 3 projects
  4. Brigham and Women's Hospital$554K · 2 projects
  5. UT Southwestern Medical Center$495K · 2 projects
  6. University of Pennsylvania$488K · 2 projects
  7. Cincinnati Childrens Hosp Med Ctr$482K · 2 projects
  8. Oregon Health & Science University$465K · 2 projects

Funding institutes

  • NIDDK$16.6M · 110

Activity codes funded

Most recent new awards

FY2026 closed on September 30, 2026, but NIH keeps posting that year's awards to RePORTER for several weeks. FY2026 figures reflect records available on October 16, 2026 and may rise slightly at the next refresh.

Participating institutes

2 NIH institutes and offices take applications under PAR-25-091. Contact the program officer at the institute that fits your research before applying.

  • NIDDK · National Institute of Diabetes and Digestive and Kidney Diseases
  • none

Related notices

  1. Jan 28, 2026 · NOT-OD-26-029

    NIH Removing AIDS Application Due Dates from NOFOs. See Notice NOT-OD-26-029.

  2. Mar 31, 2025 · NOT-OD-24-084

    This funding opportunity was updated to align with agency priorities. Carefully reread the full funding opportunity and make any needed adjustments to your application prior to submission.April 4, 2024 - Overview of Grant Application and Review Changes for Due Dates on or after January 25,…

  3. Aug 31, 2022 · NOT-OD-22-198

    Implementation Changes for Genomic Data Sharing Plans Included with Applications Due on or after January 25, 2023. See Notice NOT-OD-22-198.

  4. Aug 5, 2022 · NOT-OD-22-189

    Implementation Details for the NIH Data Management and Sharing Policy. See Notice NOT-OD-22-189.

Award terms

Application types allowed
NewResubmission - From this NOFO and PAR-22-129. The OER Glossary and the How to Apply Application Guide provide details on these application types. Only those application types listed here are allowed for this NOFO.
Award budget
Application budgets are limited to 75,000 direct costs per year and must reflect the actual needs of the proposed project.
Project period
The maximum project period is two years. NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO.
Funds available and number of awards
The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications.

Summarized from the NOFO text; the full NOFO governs eligibility, budget, and review.

Related NOFOs

  • Reissue of PAR-22-129.

Other open NOFOs for R03

Browse all open NIH NOFOs

About this page

GotGrant gathers the NOFO, its participation and change notices, and its NOSIs from the NIH Guide for Grants and Contracts, and counts funded projects from NIH RePORTER by the opportunity number each award was made under. Data refreshed October 16, 2026; the NIH Guide is the authoritative source. See our data methodology.

Find who wins under this NOFO

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