NIH RFA · NHLBI · R03

RFA-HL-27-004: Limited Competition: Small Grant Program for NHLBI K01/K08/K23/K25 Recipients (R03 Clinical Trial Optional)

Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards

Open for applicationsNext due date: Feb 10, 2027Expires Nov 8, 2028

This is a Notice of Funding Opportunity (NOFO) for a Limited Competition that invites applications from eligible organizations to apply. Please see Section III. Eligibility for additional information. In accordance with NIH standard peer-review processes, the applications will be peer-reviewed, and only meritorious applications will be considered. The purpose of this NOFO is to solicit current or recently completed NHLBI K01, K08, K23, and K25 awardees for small grant support to expand their current research objectives or to branch out to a new study emerging from their K award research. This NOFO is intended to facilitate the transition to research independence for these NHLBI K awardees.…

Full NOFO in the NIH Guide Apply on Grants.gov

NOFO number
RFA-HL-27-004
Type
RFA
Activity code
R03
Primary institute
NHLBI · National Heart, Lung, and Blood Institute
Clinical trials
Optional
Posted
May 12, 2026
Opens
Jun 9, 2026
Expires
Nov 8, 2028

RFA-HL-27-004 due dates

6 application due dates remain before the NOFO expires. Dates marked * are NIH standard due dates. Check the related notices below for changes NIH made after posting.

Application due dates and review cycles for RFA-HL-27-004
NewRenewal / Resubmission / Revision (as allowed)AIDS - New/Renewal/Resubmission/Revision, as allowedScientific Merit ReviewAdvisory Council ReviewEarliest Start Date
July 09, 2026July 09, 2026Not ApplicableNovember 2026January 2027April 2027
October 06, 2026November 06, 2026Not ApplicableMarch 2027May 2027July 2027
February 10, 2027March 10, 2027Not ApplicableJuly 2027October 2027December 2027
June 09, 2027July 09, 2027Not ApplicableNovember 2027January 2028April 2028
October 08, 2027November 08, 2027Not ApplicableMarch 2028May 2028July 2028
February 10, 2028March 10, 2028Not ApplicableJuly 2028October 2028December 2028
June 07, 2028July 07, 2028Not ApplicableNovember 2028January 2029April 2029
October 06, 2028November 07, 2028Not ApplicableMarch 2029May 2029July 2029

What its predecessor RFA-HL-25-011 funded

RFA-HL-27-004 reissues RFA-HL-25-011. Until awards appear under the new number, its funding history is the best guide to who wins under this program: 44 projects and $9.6M in FY2022–FY2026.

Projects funded

44

Distinct projects, FY2022–FY2026

New awards

44

Type 1 (new project) award records

NIH funding

$9.6M

Award dollars under RFA-HL-25-011, FY2022–FY2026

Funding by fiscal year

Award records, new awards, and funding by fiscal year under RFA-HL-25-011
Fiscal yearAward recordsNew awardsFunding
FY202200$0
FY202300$0
FY202400$0
FY202500$0
FY20264444$9.6M

Institutions with the most funding

  1. University of Alabama at Birmingham$684K · 3 projects
  2. Brigham and Women's Hospital$658K · 3 projects
  3. Yale University$504K · 2 projects
  4. University of Washington$498K · 2 projects
  5. UT Southwestern Medical Center$495K · 2 projects
  6. Columbia University Health Sciences$494K · 2 projects
  7. Johns Hopkins University$427K · 2 projects
  8. University of Tennessee Health Sci Ctr$253K · 1 project

Funding institutes

  • NHLBI$9.6M · 44

Activity codes funded

Most recent new awards

FY2026 closed on September 30, 2026, but NIH keeps posting that year's awards to RePORTER for several weeks. FY2026 figures reflect records available on October 16, 2026 and may rise slightly at the next refresh.

Participating institutes

2 NIH institutes and offices take applications under RFA-HL-27-004. Contact the program officer at the institute that fits your research before applying.

  • NHLBI · National Heart, Lung, and Blood Institute
  • none

Related notices

NIH lists no related notices for RFA-HL-27-004 yet.

Award terms

Application types allowed
New Resubmission The OER Glossary and the How to Apply Application Guide provide details on these application types. Only those application types listed here are allowed for this NOFO.
Award budget
Application budgets are limited to direct costs up to 85,000 per year, but must reflect actual needs of the proposed project.
Project period
The scope of the proposed project should determine the project period. The maximum project period is two years. NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO.
Funds available and number of awards
The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications.NHLBI intends to commit total costs up to 3.9 million in FY2027, 7.8 million in FY2028, 7.8 million in FY2029, and 3.9 million in FY2030 for this program.NHLBI intends to fund up to 29 new awards per year in FY2027, FY2028, and FY2029.

Summarized from the NOFO text; the full NOFO governs eligibility, budget, and review.

Related NOFOs

  • Reissue of RFA-HL-25-011.

Other open NOFOs for R03

Browse all open NIH NOFOs

About this page

GotGrant gathers the NOFO, its participation and change notices, and its NOSIs from the NIH Guide for Grants and Contracts, and counts funded projects from NIH RePORTER by the opportunity number each award was made under. Data refreshed October 16, 2026; the NIH Guide is the authoritative source. See our data methodology.

Find who wins under this NOFO

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