NIH PA · NICHD · R03

PA-25-125: NICHD Small Research Grant Program (R03 Clinical Trial Required)

Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards

Open for applicationsNext due date: Oct 16, 2026Expires Jan 8, 2028

The NICHD Small Research Grant Program (Clinical Trial Required) supports clinical trials that fall within the NICHD mission.

Full NOFO in the NIH Guide Apply on Grants.gov

NOFO number
PA-25-125
Type
PA
Activity code
R03
Primary institute
NICHD · Eunice Kennedy Shriver National Institute of Child Health and Human Development
Clinical trials
Required
Posted
Nov 18, 2024
Opens
Jan 16, 2025
Expires
Jan 8, 2028

PA-25-125 due dates

4 application due dates remain before the NOFO expires. Dates marked * are NIH standard due dates. Check the related notices below for changes NIH made after posting.

Application due dates and review cycles for PA-25-125
Application Due Date(s)Renewal / Resubmission / Revision (as allowed)AIDS - New/Renewal/Resubmission/Revision, as allowedScientific Merit ReviewAdvisory Council ReviewEarliest Start Date
February 16, 2025March 16, 2025 *May 07, 2025 *July 2025October 2025December 2025
June 16, 2025July 16, 2025 *September 07, 2025 *November 2025January 2026April 2026
October 16, 2025November 16, 2025 *January 07, 2026 *March 2026May 2026July 2026
February 16, 2026March 16, 2026 *May 07, 2026 *July 2026October 2026December 2026
June 16, 2026July 16, 2026 *Not ApplicableNovember 2026January 2027April 2027
October 16, 2026November 16, 2026 *Not ApplicableMarch 2027May 2027July 2027
February 16, 2027March 16, 2027 *Not ApplicableJuly 2027October 2027December 2027
June 16, 2027July 16, 2027 *Not ApplicableNovember 2027January 2028April 2028
October 16, 2027November 16, 2027 *Not ApplicableMarch 2028May 2028July 2028

What its predecessor PA-21-221 funded

PA-25-125 reissues PA-21-221. Until awards appear under the new number, its funding history is the best guide to who wins under this program: 8 projects and $1.2M in FY2022–FY2026.

Projects funded

8

Distinct projects, FY2022–FY2026

New awards

8

Type 1 (new project) award records

NIH funding

$1.2M

Award dollars under PA-21-221, FY2022–FY2026

Funding by fiscal year

Award records, new awards, and funding by fiscal year under PA-21-221
Fiscal yearAward recordsNew awardsFunding
FY202211$81K
FY202310$81K
FY202433$455K
FY202544$608K
FY202600$0

Institutions with the most funding

  1. Rehabilitation Institute of Chicago D/B/A Shirley Ryan Abilitylab$165K · 1 project
  2. University of California, San Francisco$162K · 1 project
  3. University of Pittsburgh at Pittsburgh$159K · 1 project
  4. University of Central Florida$152K · 1 project
  5. Virginia Polytechnic Inst and St Univ$151K · 1 project
  6. Utah State Higher Education System--University of Utah$148K · 1 project
  7. Miami University Oxford$147K · 1 project
  8. University of North Florida$142K · 1 project

Funding institutes

  • NICHD$1.2M · 9

Activity codes funded

Most recent new awards

FY2026 closed on September 30, 2026, but NIH keeps posting that year's awards to RePORTER for several weeks. FY2026 figures reflect records available on October 16, 2026 and may rise slightly at the next refresh.

Participating institutes

2 NIH institutes and offices take applications under PA-25-125. Contact the program officer at the institute that fits your research before applying.

  • NICHD · Eunice Kennedy Shriver National Institute of Child Health and Human Development
  • none

Related notices

  1. Jan 28, 2026 · NOT-OD-26-029

    NIH Removing AIDS Application Due Dates from NOFOs.

  2. Mar 31, 2025 · NOT-OD-24-084

    This funding opportunity was updated to align with agency priorities. Carefully reread the full funding opportunity and make any needed adjustments to your application prior to submission.April 4, 2024 - Overview of Grant Application and Review Changes for Due Dates on or after January 25,…

  3. Aug 31, 2022 · NOT-OD-22-198

    Implementation Changes for Genomic Data Sharing Plans Included with Applications Due on or after January 25, 2023. See Notice NOT-OD-22-198.

  4. Aug 5, 2022 · NOT-OD-22-189

    Implementation Details for the NIH Data Management and Sharing Policy. See Notice NOT-OD-22-189.

Notices of Special Interest (NOSIs)

NIH has attached 3 NOSIs to PA-25-125; none are active now. A NOSI flags a topic an institute wants to fund through this NOFO.

Award terms

Application types allowed
NewResubmission The OER Glossary and the How to Apply Application Guide provide details on these application types. Only those application types listed here are allowed for this NOFO.
Award budget
Application budgets are limited to 50,000 in direct costs per year.
Project period
The maximum project period is two years. NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO.
Funds available and number of awards
The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications.

Summarized from the NOFO text; the full NOFO governs eligibility, budget, and review.

Related NOFOs

  • Reissue of PA-21-221.
  • Companion NOFOs: PA-25-126.

Other open NOFOs for R03

Browse all open NIH NOFOs

About this page

GotGrant gathers the NOFO, its participation and change notices, and its NOSIs from the NIH Guide for Grants and Contracts, and counts funded projects from NIH RePORTER by the opportunity number each award was made under. Data refreshed October 16, 2026; the NIH Guide is the authoritative source. See our data methodology.

Find who wins under this NOFO

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