NIH funding profile · Rochester, MN · Nonprofit
Mayo Clinic Rochester NIH Funding
Also known as Mayo Clinic
Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards
Mayo Clinic Rochester received $322.5M in NIH award funding in fiscal year 2026 across 397 award records and 381 principal investigators. That ranks #29 of 2,407 NIH-funded institutions and #2 in Minnesota, up 11.3% from FY2025.
Part of Mayo Clinic. See its combined NIH funding across every member NIH records separately.
FY2026 closed on September 30, 2026, but NIH keeps posting that year's awards to RePORTER for several weeks. FY2026 figures reflect records available on October 16, 2026 and may rise slightly at the next refresh.
FY2026 NIH funding
$322.5M
+11.3% vs FY2025
National rank
#29
Up 6 places from #35 vs FY2025
Rank in Minnesota
#2
41.4% of Minnesota NIH funding
Awards · PIs
397
381 investigators · 86 new projects
NIH funding trend, FY2022–FY2026
Mayo Clinic Rochester received $1.41B in NIH awards over these five fiscal years. Annual funding moved +27.6% from FY2022 to FY2026. Its best national rank in the period was #29 (FY2026).
NIH institutes funding Mayo Clinic Rochester, FY2026
22 NIH institutes and centers administered awards here in FY2026. The largest, the National Cancer Institute (NCI), accounted for 23.1% of the institution's NIH funding across 91 awards.
- NCI · National Cancer Institute$74.3M · 23.1%
91 awards · vs FY2025: +10.9%
- NIA · National Institute on Aging$60.4M · 18.7%
48 awards · vs FY2025: +0.5%
- OD · NIH Office of the Director$43.0M · 13.3%
2 awards · vs FY2025: +99.5%
- NIDDK · National Institute of Diabetes and Digestive and Kidney Diseases$40.9M · 12.7%
80 awards · vs FY2025: +0.7%
- NHLBI · National Heart, Lung, and Blood Institute$33.8M · 10.5%
59 awards · vs FY2025: +3.0%
- NINDS · National Institute of Neurological Disorders and Stroke$18.7M · 5.8%
28 awards · vs FY2025: +41.0%
- NIAID · National Institute of Allergy and Infectious Diseases$11.4M · 3.5%
24 awards · vs FY2025: +48.9%
- NCATS · National Center for Advancing Translational Sciences$9.5M · 3.0%
3 awards · vs FY2025: −3.4%
- NIAMS · National Institute of Arthritis and Musculoskeletal and Skin Diseases$5.4M · 1.7%
11 awards · vs FY2025: −29.6%
- NIGMS · National Institute of General Medical Sciences$4.1M · 1.3%
9 awards · vs FY2025: −39.4%
Also: NIBIB $4.0M · NIAAA $3.8M · NICHD $2.9M · NIDA $2.3M · NIDCD $2.1M · NIMH $1.6M · NHGRI $1.5M · NEI $936K · NIDCR $576K · NLM $374K · NCCIH $362K · NIMHD $319K
Award mechanism mix
Share of NIH award dollars by activity-code family in FY2026, with the FY2022 share for comparison. R01-equivalent research grants were 49.2% of funding.
- R01-equivalent49.2% · FY22 50.7%
- Cooperative agreements (U)20.5% · FY22 27.3%
- Other13.3% · FY22 0.0%
- Centers & program projects (P)8.1% · FY22 8.1%
- Other research (R)4.5% · FY22 8.0%
- Career development (K)2.2% · FY22 3.2%
- Institutional training (T)1.9% · FY22 2.0%
- Fellowships (F)0.2% · FY22 0.2%
- Contracts (N)0.0% · FY22 0.5%
Top activity codes, FY2026
| Code | Awards | Funding | Share | Average award |
|---|---|---|---|---|
| R01 | 231 | $144.7M | 44.9% | $626K |
| OT2 | 2 | $43.0M | 13.3% | $21.5M |
| U19 | 6 | $24.1M | 7.5% | $4.0M |
| U01 | 20 | $14.1M | 4.4% | $704K |
| P30 | 4 | $12.0M | 3.7% | $3.0M |
| P50 | 5 | $10.7M | 3.3% | $2.1M |
| U10 | 1 | $9.7M | 3.0% | $9.7M |
| R37 | 11 | $8.9M | 2.8% | $812K |
| UL1 | 1 | $7.5M | 2.3% | $7.5M |
| T32 | 11 | $4.7M | 1.5% | $430K |
| RF1 | 2 | $4.6M | 1.4% | $2.3M |
| R35 | 7 | $3.9M | 1.2% | $553K |
Largest FY2026 awards
The biggest single award records by FY2026 dollars. Each links to its NIH RePORTER project page.
- All of Us Biobank (opens NIH RePORTER)
3OT2OD039849-01S2 · OD
$21.9MOT2
- All of Us Biobank (opens NIH RePORTER)
3OT2OD039849-01S1 · OD
$21.1MOT2
- ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration, Cycle 2 (ALLFTD2) (opens NIH RePORTER)
5U19AG063911-07 · NIA
$18.7MU19
- Alliance Statistics and Data Management Center (opens NIH RePORTER)
2U10CA180882-12 · NCI
$9.7MU10
- Mayo Clinic Center for Clinical and Translational Science (CCaTS) (opens NIH RePORTER)
5UL1TR002377-10 · NCATS
$7.5MUL1
- Mayo Clinic Comprehensive Cancer Center Support Grant (opens NIH RePORTER)
5P30CA015083-51 · NCI
$5.7MP30
Recently started projects
The latest new (Type 1) FY2026 awards by notice date, out of 86 new projects NIH funded here this year.
- Temporal Associations of Neuroinflammation with Alzheimer’s Disease Biomarkers and Cognition (opens NIH RePORTER)
1R01AG102933-01 · NIA · Notice Sep 29, 2026
$678KR01
- Expanding the ClinGen Lysosomal Storage Disorder Curation Effort: VCEPs for Mucopolysaccharidosis Type II and IIIA (opens NIH RePORTER)
1U24HD121485-01 · NICHD · Notice Sep 23, 2026
$353KU24
- Mayo Clinic / University of Minnesota Prostate SPORE (opens NIH RePORTER)
1P50CA298941-01A1 · NCI · Notice Sep 17, 2026
$2.2MP50
- Effects of Sleep Restriction on Glycemic Control and Cardiovascular Risk Mechanisms in Type 1 Diabetes Mellitus (opens NIH RePORTER)
1R01HL178855-01A1 · NHLBI · Notice Sep 17, 2026
$806KR01
- Targeting PAR1 to overcome myelin deficits in aging and Alzheimer’s disease (opens NIH RePORTER)
1R01AG103649-01 · NIA · Notice Sep 17, 2026
$663KR01
- Exploring the contribution of non-coding and somatic copy number variations to the Tourette Disorder (opens NIH RePORTER)
1R03NS148680-01A1 · NINDS · Notice Sep 17, 2026
$161KR03
Other NIH-funded institutions in Minnesota
| # | Institution | Funding |
|---|---|---|
| 1 | University of MinnesotaMinneapolis, MN | $391.8M |
| 2 | Mayo Clinic RochesterRochester, MN | $322.5M |
| 3 | Healthpartners InstituteBloomington, MN | $11.6M |
Nearby in the national ranking
| # | Institution | Funding |
|---|---|---|
| 26 | Weill Cornell MedicineNew York, NY | $352.7M |
| 27 | University of Alabama at BirminghamBirmingham, AL | $335.6M |
| 28 | Fred Hutchinson Cancer CenterSeattle, WA | $332.3M |
| 29 | Mayo Clinic RochesterRochester, MN | $322.5M |
| 30 | UT Southwestern Medical CenterDallas, TX | $309.0M |
| 31 | University of California, DavisDavis, CA | $308.2M |
| 32 | Oregon Health & Science UniversityPortland, OR | $297.6M |
Similar research institutes and nonprofits
| # | Institution | Funding |
|---|---|---|
| 28 | Fred Hutchinson Cancer CenterSeattle, WA | $332.3M |
| 29 | Mayo Clinic RochesterRochester, MN | $322.5M |
| 41 | Sloan Kettering Institute for Cancer ResearchNew York, NY | $231.1M |
| 59 | Research Triangle InstituteResearch Triangle Park, NC | $166.0M |
| 60 | Broad Institute of MIT and HarvardCambridge, MA | $157.2M |
| 61 | Scripps ResearchLa Jolla, CA | $155.5M |
| 88 | Kaiser Foundation Research InstituteOakland, CA | $98.9M |
About these numbers
Source: the public NIH RePORTER API, refreshed October 16, 2026. See our data methodology and the guide to reading NIH funding rankings by university.
- Who is countedAwards made to NIH recipient organization code 4976101. A university's medical school, affiliated hospital, or other campuses can be separate NIH recipients with their own totals.
- What is countedTotal award amount (direct plus indirect) obligated in each fiscal year for grants, cooperative agreements, training awards, SBIR/STTR, and R&D contracts. Subprojects, intramural research, and interagency agreements are excluded.
- InstitutesEach award is credited in full to its administering institute, even when other institutes co-fund it.
- SubawardsNIH reports the prime recipient only, so research this institution performs under another organization's grant is not included here.