NIH R37 Grants — MERIT Award

Recent R37 awards from NIH RePORTER

Examples of funded R37 projects across the last two fiscal years. The matching-award count comes from the full result set; funding totals, averages, rankings, and examples use the first 500 records returned by NIH RePORTER. Figures reflect a snapshot last refreshed on June 9, 2026.

Example R37 projects from the sample

• Reducing ReADmissions through Innovative ApplicatioNs of Telemedicine (RADIANT)

  1R37CA300137-01A1
  Robert Daly · SLOAN-KETTERING INST CAN RESEARCH, NY · $747,660 · awarded Jun 5, 2026 · NIH

  PROJECT SUMMARY The Reducing ReADmissions through Innovative ApplicatioNs of Telemedicine (RADIANT) trial aims to build the evidence base necessary to establish a scalable remote patient monitoring (RPM) and integrative medicine (IM) intervention delivered via telemedicine platform to medical oncology patients discharged to home after hospitalization. The…

• Mechanistic Studies of Replication Initiation in Prokaryotes

  5R37GM071747-22
  James Berger · JOHNS HOPKINS UNIVERSITY, MD · $408,052 · awarded Jun 3, 2026 · NIH

  A long-term goal of our research is to define the molecular mechanisms underpinning the initiation of cellular DNA replication. Initiation represents a central commitment to cell proliferation; inappropriate onset of replication can lead to genetic instabilities, DNA damage, and changes in gene copy number. From a biomedical perspective, initiation is a…

• Development and validation of an autologous mouse model for the study of immune interactions with glioblastoma

  5R37CA285434-03
  Zev Binder · UNIVERSITY OF PENNSYLVANIA, PA · $727,211 · awarded Jun 3, 2026 · NIH

  Project Summary An adaptive immunosuppressive microenvironment is a major barrier to immune-based therapies for solid tumors, including glioblastoma (GBM). Current model systems for preclinical development either lack substantial components of the immune system or rely upon different species’ immune systems, which display significant differences when…

• Regulation of repetitive elements in cancer by p53 and epigenetic mechanisms

  4R37CA251270-06
  Katherine Chiappinelli · GEORGE WASHINGTON UNIVERSITY, DC · $370,670 · awarded Jun 3, 2026 · NIH

  Despite focused research efforts, the five year survival for ovarian cancer (OC) has remained unchanged for decades and novel therapies are urgently needed for this deadly disease. Therapies that activate the immune system to kill cancer cells, including anti-PD-1 checkpoint blockade therapy, have shown vigorous and durable responses, but the majority of…

• Regulation of axonal degeneration by the DLK kinase

  5R37NS065053-14
  Aaron Diantonio · WASHINGTON UNIVERSITY, MO · $647,456 · awarded Jun 3, 2026 · NIH

  Project Summary/Abstract: Axonal degeneration is an early and likely initiating event in many of the most prevalent neurodegenerative diseases. DLK is a major neuronal stress kinase that we identified as the first gene required for pathological axon degeneration. Recently we defined the mechanism: DLK promotes the turnover of the axon maintenance factors…

• Reproductive physiology of gonadotropin synthesis

  5R37HD019938-34
  Ursula Kaiser · BRIGHAM AND WOMEN'S HOSPITAL, MA · $552,353 · awarded Jun 3, 2026 · NIH

  Reproduction is a tightly regulated function of an organism that is crucial to the perpetuation of a species. The pituitary gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), play an essential role in the reproductive process to control fertility by directing steroidogenesis and gametogenesis. Befitting their important roles in…

• Mechanisms of nicotine reinforcement

  5R37DA020686-19
  Paul Kenny · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY · $417,916 · awarded Jun 3, 2026 · NIH

  This application for renewal seeks to better understand the neurobiological mechanisms of nicotine addiction. A major accomplishment during the previous funding cycle was identifying the critical role played by the habenula-interpeduncular nucleus (habenula-IPn) circuit in regulating the motivational properties of nicotine. We also found that the…

• Defining and exploiting therapeutically the role of the neuropeptide receptor PAC1 in tumor-infiltrating pericytes that drives melanoma progression.

  1R37CA300434-01A1
  Alexander Birbrair · UNIVERSITY OF WISCONSIN-MADISON, WI · $508,651 · awarded Jun 1, 2026 · NIH

  PROJECT SUMMARY The overall objective of this study is to understand and exploit therapeutically the role of neuropeptide receptor PAC1 in melanoma-infiltrating pericytes during melanoma progression. Melanoma is the most lethal form of skin cancer due to its tendency to rapidly metastasize, and current therapies often do not achieve durable responses. Novel…

• TRANSCRANIAL FUS THERAPY WITH CLOSED-LOOP US IMAGE GUIDANCE AND CIRCULATING

  5R37CA239039-07
  Konstantinos-Costas Arvanitis · GEORGIA INSTITUTE OF TECHNOLOGY, GA · $451,467 · awarded May 28, 2026 · NIH

  Project summary A major obstacle towards attaining sufficient accumulation of blood-borne therapeutics in the brain and brain tumors is posed by the blood-brain barrier. Circulating microbubbles upon ultrasound exposure can exert mechanical stress in brain vessels to trigger a range of responses pertinent to key regulatory processes of the blood brain…

• Altered Midbrain GABAergic Circuitry Drives Greater Cocaine Self-administration

  4R37DA053296-06
  John Dani · UNIVERSITY OF PENNSYLVANIA, PA · $485,446 · awarded May 28, 2026 · NIH

  Project Summary. Cocaine is the most widely abused psychostimulant by a wide margin, and it remains a major public health problem in the US. Cocaine use was slowly declining, but in recent years there has been a resurgence in cocaine abuse accompanied by a sharp increase in cocaine-related hospitalizations and deaths. These facts highlight the need for…

• Survival Function of the Fadd-Caspase-8-Flip Complex - MERIT Extension

  5R37AI044828-28
  Douglas Green · ST. JUDE CHILDREN'S RESEARCH HOSPITAL, TN · $455,000 · awarded May 28, 2026 · NIH

  Necroptosis, in which the FADD-caspase-8-FLIP complex controls RIPK3-MLKL-mediated cell death, is an inflammatory cell death process that is engaged by TNF and related ligands, TLR signaling (involving TRIF) and interferons. Necroptosis has been implicated in development and adult homeostasis. Through genetic models and in vitro cell-based experiments, we…

• Longitudinal Radio-pathomic Mapping of Non-Enhancing Tumor Growth in Glioblastoma

  1R37CA311064-01
  Samuel Bobholz · MEDICAL COLLEGE OF WISCONSIN, WI · $602,121 · awarded May 26, 2026 · NIH

  Project Summary Glioblastoma (GBM) remains the most aggressive primary brain tumor with median survival of only 12-15 months despite intensive multimodal therapy. Current treatment paradigms focus primarily on contrast-enhancing tumor regions visible on MRI, failing to adequately address non-enhancing tumor components that harbor resistant cells and serve…

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