NIH RFA · NCI · R33

RFA-CA-27-002: Advanced Development and Validation of Emerging Technologies for Basic and Clinical Cancer Research (R33 Clinical Trial Not Allowed)

Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards

Open for applicationsNext due date: Nov 10, 2026Expires Nov 11, 2026

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) invites grant applications proposing exploratory research projects focused on further development and technical validation of emerging technologies offering novel capabilities for the molecular or cellular characterization of cancer or for improved handling and quality control of biospecimens used for basic, clinical, or epidemiological cancer research. This NOFO solicits R33 applications where major feasibility gaps for the technology or methodology have been overcome, as demonstrated with supportive preliminary data, but still require further development and rigorous technical validation to encourage…

Full NOFO in the NIH Guide Apply on Grants.gov

NOFO number
RFA-CA-27-002
Type
RFA
Activity code
R33
Primary institute
NCI · National Cancer Institute
Clinical trials
Not Allowed
Posted
Jun 3, 2026
Opens
Jun 10, 2026
Expires
Nov 11, 2026

RFA-CA-27-002 due dates

1 application due date remains before the NOFO expires. Dates marked * are NIH standard due dates. Check the related notices below for changes NIH made after posting.

Application due dates and review cycles for RFA-CA-27-002
NewRenewal / Resubmission / Revision (as allowed)AIDS - New/Renewal/Resubmission/Revision, as allowedScientific Merit ReviewAdvisory Council ReviewEarliest Start Date
July 10, 2026July 10, 2026Not ApplicableNovember 2026January 2027April 2027
November 10, 2026November 10, 2026Not ApplicableFebruary 2027May 2027July 2027

What its predecessor RFA-CA-25-002 funded

RFA-CA-27-002 reissues RFA-CA-25-002. Until awards appear under the new number, its funding history is the best guide to who wins under this program: 10 projects and $4.1M in FY2022–FY2026.

Projects funded

10

Distinct projects, FY2022–FY2026

New awards

10

Type 1 (new project) award records

NIH funding

$4.1M

Award dollars under RFA-CA-25-002, FY2022–FY2026

Funding by fiscal year

Award records, new awards, and funding by fiscal year under RFA-CA-25-002
Fiscal yearAward recordsNew awardsFunding
FY202200$0
FY202300$0
FY202400$0
FY202500$0
FY20261010$4.1M

Institutions with the most funding

  1. Yale University$837K · 2 projects
  2. Jackson Laboratory$452K · 1 project
  3. Dana-Farber Cancer Inst$432K · 1 project
  4. Beth Israel Deaconess Medical Center$431K · 1 project
  5. University of Connecticut Sch of Med/Dnt$415K · 1 project
  6. University of Washington$405K · 1 project
  7. Duke University$402K · 1 project
  8. University of Chicago$388K · 1 project

Funding institutes

  • NCI$4.1M · 10

Activity codes funded

  • R3310 records

Most recent new awards

FY2026 closed on September 30, 2026, but NIH keeps posting that year's awards to RePORTER for several weeks. FY2026 figures reflect records available on October 16, 2026 and may rise slightly at the next refresh.

Participating institutes

2 NIH institutes and offices take applications under RFA-CA-27-002. Contact the program officer at the institute that fits your research before applying.

  • NCI · National Cancer Institute
  • none

Related notices

NIH lists no related notices for RFA-CA-27-002 yet.

Award terms

Application types allowed
New Resubmission The OER Glossary and the How to Apply Application Guide provide details on these application types. Only those application types listed here are allowed for this NOFO.
Award budget
Application budgets are limited to 300,000 per year in direct costs).
Project period
The total project period request may not exceed 3 years. NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO.
Funds available and number of awards
NCI intends to fund an estimate of 13 awards, corresponding to a total of 5,900,000, for the fiscal year 2027. Future year amounts will depend on annual appropriations.

Summarized from the NOFO text; the full NOFO governs eligibility, budget, and review.

Related NOFOs

Other open NOFOs for R33

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About this page

GotGrant gathers the NOFO, its participation and change notices, and its NOSIs from the NIH Guide for Grants and Contracts, and counts funded projects from NIH RePORTER by the opportunity number each award was made under. Data refreshed October 16, 2026; the NIH Guide is the authoritative source. See our data methodology.

Find who wins under this NOFO

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