NIH RFA · NCI · R61

RFA-CA-27-001: Early-Stage Innovative Technology Development for Basic and Clinical Cancer Research (R61 Clinical Trial Not Allowed)

Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards

Open for applicationsNext due date: Nov 10, 2026Expires Nov 11, 2026

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) solicits grant applications proposing to develop innovative technologies offering new capabilities for the molecular or cellular characterization of cancer or for improved handling and quality control of biospecimens for basic, clinical, or epidemiological cancer research. The NOFO solicits R61 applications for early-stage projects proposing proof-of-concept/pilot studies to test the technical feasibility of the proposed method, tool, assay, platform, or instrument. Technologies proposed for development may have potential for widespread applicability but must be focused for this program on cancer-relevant…

Full NOFO in the NIH Guide Apply on Grants.gov

NOFO number
RFA-CA-27-001
Type
RFA
Activity code
R61
Primary institute
NCI · National Cancer Institute
Clinical trials
Not Allowed
Posted
Jun 3, 2026
Opens
Jun 10, 2026
Expires
Nov 11, 2026

RFA-CA-27-001 due dates

1 application due date remains before the NOFO expires. Dates marked * are NIH standard due dates. Check the related notices below for changes NIH made after posting.

Application due dates and review cycles for RFA-CA-27-001
NewRenewal / Resubmission / Revision (as allowed)AIDS - New/Renewal/Resubmission/Revision, as allowedScientific Merit ReviewAdvisory Council ReviewEarliest Start Date
July 10, 2026July 10, 2026Not ApplicableNovember 2026January 2027April 2027
November 10, 2026November 10, 2026Not ApplicableFebruary 2027May 2027July 2027

What its predecessor RFA-CA-25-001 funded

RFA-CA-27-001 reissues RFA-CA-25-001. Until awards appear under the new number, its funding history is the best guide to who wins under this program: 11 projects and $2.5M in FY2022–FY2026.

Projects funded

11

Distinct projects, FY2022–FY2026

New awards

11

Type 1 (new project) award records

NIH funding

$2.5M

Award dollars under RFA-CA-25-001, FY2022–FY2026

Funding by fiscal year

Award records, new awards, and funding by fiscal year under RFA-CA-25-001
Fiscal yearAward recordsNew awardsFunding
FY202200$0
FY202300$0
FY202400$0
FY202500$0
FY20261111$2.5M

Institutions with the most funding

  1. New York Genome Center$271K · 1 project
  2. Broad Institute, Inc.$245K · 1 project
  3. Rutgers Biomedical and Health Sciences$239K · 1 project
  4. Harvard Medical School$237K · 1 project
  5. Duke University$232K · 1 project
  6. University of Southern California$227K · 1 project
  7. University of Illinois at Chicago$225K · 1 project
  8. University of Michigan at Ann Arbor$219K · 1 project

Funding institutes

  • NCI$2.5M · 11

Activity codes funded

  • R6111 records

Most recent new awards

FY2026 closed on September 30, 2026, but NIH keeps posting that year's awards to RePORTER for several weeks. FY2026 figures reflect records available on October 16, 2026 and may rise slightly at the next refresh.

Participating institutes

2 NIH institutes and offices take applications under RFA-CA-27-001. Contact the program officer at the institute that fits your research before applying.

  • NCI · National Cancer Institute
  • none

Related notices

NIH lists no related notices for RFA-CA-27-001 yet.

Award terms

Application types allowed
New Resubmission The OER Glossary and the How to Apply Application Guide provide details on these application types. Only those application types listed here are allowed for this NOFO.
Award budget
Application budgets are limited to 150,000 per year direct costs).
Project period
The total project period request may not exceed 3 years. NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO.
Funds available and number of awards
NCI intends to commit a total of 5,100,000, in fiscal year 2027 to fund an estimated 20 awards. Future year amounts will depend on annual appropriations.

Summarized from the NOFO text; the full NOFO governs eligibility, budget, and review.

Related NOFOs

Other open NOFOs for R61

Browse all open NIH NOFOs

About this page

GotGrant gathers the NOFO, its participation and change notices, and its NOSIs from the NIH Guide for Grants and Contracts, and counts funded projects from NIH RePORTER by the opportunity number each award was made under. Data refreshed October 16, 2026; the NIH Guide is the authoritative source. See our data methodology.

Find who wins under this NOFO

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