NIH PAR · NIDCD · U01
PAR-25-343: NIDCD Cooperative Agreement for Clinical Trials in Communication Disorders (U01 - Clinical Trial Required)
Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards
The NIDCD is committed to identifying effective interventions for the treatment or prevention of communication disorders by supporting well designed and well executed clinical trials. This funding opportunity announcement (FOA) supports a cooperative agreement between an NIDCD Project Scientist and an investigator to support a clinical trial that meets ANY of the following criteria: requires FDA oversight, is intended to formally establish efficacy, or has a higher risk to potentially cause physical or psychological harm.
- NOFO number
- PAR-25-343
- Type
- PAR
- Activity code
- U01
- Primary institute
- NIDCD · National Institute on Deafness and Other Communication Disorders
- Clinical trials
- Required
- Posted
- Jan 6, 2025
- Opens
- Jan 27, 2025
- Expires
- Oct 19, 2027
PAR-25-343 due dates
4 application due dates remain before the NOFO expires. Dates marked * are NIH standard due dates. Check the related notices below for changes NIH made after posting.
| Application Due Date(s) | Renewal / Resubmission / Revision (as allowed) | AIDS - New/Renewal/Resubmission/Revision, as allowed | Scientific Merit Review | Advisory Council Review | Earliest Start Date |
|---|---|---|---|---|---|
| February 27, 2025 | February 27, 2025 | Not Applicable | July 2025 | October 2025 | December 2025 |
| June 18, 2025 | June 18, 2025 | Not Applicable | November 2025 | January 2026 | April 2026 |
| October 17, 2025 | October 17, 2025 | Not Applicable | March 2026 | May 2026 | July 2026 |
| February 18, 2026 | February 18, 2026 | Not Applicable | July 2026 | October 2026 | December 2026 |
| June 18, 2026 | June 18, 2026 | Not Applicable | November 2026 | January 2027 | April 2027 |
| October 19, 2026 | October 19, 2026 | Not Applicable | March 2027 | May 2027 | July 2027 |
| February 18, 2027 | February 18, 2027 | Not Applicable | July 2027 | October 2027 | December 2027 |
| June 18, 2027 | June 18, 2027 | Not Applicable | November 2027 | January 2028 | April 2028 |
| October 18, 2027 | October 18, 2027 | Not Applicable | March 2028 | May 2028 | July 2028 |
Projects funded under PAR-25-343
NIH RePORTER lists 2 projects funded under PAR-25-343 in FY2022–FY2026, with $1.9M in award dollars. Counts include each project's later non-competing years, which keep the original NOFO number.
Projects funded
2
Distinct projects, FY2022–FY2026
New awards
2
Type 1 (new project) award records
NIH funding
$1.9M
Award dollars under PAR-25-343, FY2022–FY2026
Funding by fiscal year
| Fiscal year | Award records | New awards | Funding |
|---|---|---|---|
| FY2022 | 0 | 0 | $0 |
| FY2023 | 0 | 0 | $0 |
| FY2024 | 0 | 0 | $0 |
| FY2025 | 0 | 0 | $0 |
| FY2026 | 2 | 2 | $1.9M |
Institutions with the most funding
- University of Pennsylvania$1.1M · 1 project
- Univ of Arkansas for Med Scis$824K · 1 project
Funding institutes
- NIDCD$1.9M · 2
Activity codes funded
- U012 records
Most recent new awards
- Chemosensory Diagnostics in Clinical Care: Identifying a Scalable Standard of Care for Disease Diagnosis and Management (opens NIH RePORTER)
University of Pennsylvania · 1U01DC024405-01 · NIDCD · Notice Sep 17, 2026
$1.1MU01
- STAR+ Trial: Expanding Access to Hearing Diagnostics and Treatment for Children in Rural Appalachia (opens NIH RePORTER)
Univ of Arkansas for Med Scis · 1U01DC024017-01 · NIDCD · Notice Sep 14, 2026
$824KU01
What its predecessor PAR-24-050 funded
PAR-25-343 reissues PAR-24-050. Its funding history is the best guide to who wins under this program: 1 project and $2.4M in FY2022–FY2026.
Projects funded
1
Distinct projects, FY2022–FY2026
New awards
1
Type 1 (new project) award records
NIH funding
$2.4M
Award dollars under PAR-24-050, FY2022–FY2026
Funding by fiscal year
| Fiscal year | Award records | New awards | Funding |
|---|---|---|---|
| FY2022 | 0 | 0 | $0 |
| FY2023 | 0 | 0 | $0 |
| FY2024 | 0 | 0 | $0 |
| FY2025 | 1 | 1 | $1.2M |
| FY2026 | 1 | 0 | $1.2M |
Institutions with the most funding
- University of South Carolina at Columbia$2.4M · 1 project
Funding institutes
- NIDCD$2.4M · 2
Activity codes funded
- U012 records
Most recent new awards
- Transcranial Direct Current Stimulation to Treat Aphasia: A Superiority Study (opens NIH RePORTER)
University of South Carolina at Columbia · 1U01DC022447-01A1 · NIDCD · Notice Aug 26, 2025
$1.2MU01
FY2026 closed on September 30, 2026, but NIH keeps posting that year's awards to RePORTER for several weeks. FY2026 figures reflect records available on October 16, 2026 and may rise slightly at the next refresh.
Participating institutes
2 NIH institutes and offices take applications under PAR-25-343. Contact the program officer at the institute that fits your research before applying.
- NIDCD · National Institute on Deafness and Other Communication Disorders
- none
Related notices
Mar 31, 2025 · NOT-OD-24-084
This funding opportunity was updated to align with agency priorities. Carefully reread the full funding opportunity and make any needed adjustments to your application prior to submission.April 4, 2024 - Overview of Grant Application and Review Changes for Due Dates on or after January 25,…
Aug 31, 2022 · NOT-OD-22-198
Implementation Changes for Genomic Data Sharing Plans Included with Applications Due on or after January 25, 2023. See Notice NOT-OD-22-198.
Aug 5, 2022 · NOT-OD-22-189
Implementation Details for the NIH Data Management and Sharing Policy. See Notice NOT-OD-22-189.
Notices of Special Interest (NOSIs)
NIH has attached 3 NOSIs to PAR-25-343; none are active now. A NOSI flags a topic an institute wants to fund through this NOFO.
Award terms
- Application types allowed
- NewRenewalResubmissionRevision The OER Glossary and the How to Apply Application Guide provide details on these application types. Only those application types listed here are allowed for this NOFO.
- Award budget
- Application budgets are not limited but need to reflect the actual needs of the proposed project.
- Project period
- The scope of the proposed project should determine the project period. The maximum project period is 5 years. NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO.
- Funds available and number of awards
- The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications.
Summarized from the NOFO text; the full NOFO governs eligibility, budget, and review.
Related NOFOs
- Reissue of PAR-24-050.
Other open NOFOs for U01
- PAR-26-116Opportunities for Collaborative Research at the NIH Clinical Center (U01 Clinical Trial Optional)OD · next due Feb 5, 2027
- RFA-NS-27-015BRAIN Initiative Connectivity across Scales (BRAIN CONNECTS): Specialized Projects for Scalable Technologies (U01 Clinical Trial Not Allowed)NINDS · next due Feb 8, 2027
- RFA-MH-26-140BRAIN Initiative: Brain Behavior Quantification and Synchronization- Next Generation Sensor Technology Development (U01 Clinical Trial Optional)NIMH · next due Jun 15, 2027
- RFA-CA-27-019Early-Stage Development of Informatics Technologies for Cancer Research and Management (U01 Clinical Trial Optional)NCI · next due Oct 19, 2026
- RFA-DE-27-001Community Engagement Evaluation and Data Coordination (CEED) Hub to Advance Data and Practice Transformation for Optimizing Oral Health for All (U01, Clinical Trial Not Allowed)NIDCR · next due Oct 19, 2026
- PAR-25-352National Cooperative Drug/Device Discovery/Development Groups (NCDDG) for the Treatment of Mental Disorders (U01 Clinical Trial Optional)NIMH · next due Oct 25, 2026
About this page
GotGrant gathers the NOFO, its participation and change notices, and its NOSIs from the NIH Guide for Grants and Contracts, and counts funded projects from NIH RePORTER by the opportunity number each award was made under. Data refreshed October 16, 2026; the NIH Guide is the authoritative source. See our data methodology.