NIH PAR · NCI · K99, R00
PAR-25-313: NCI Pathway to Independence Award (K99/R00 Clinical Trial Required)
Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards
The purpose of the NCI Pathway to Independence Award (K99/R00) program is to facilitate a timely transition of talented postdoctoral researchers with a research and/or clinical doctorate degree from mentored, postdoctoral research positions to independent, tenure-track or equivalent faculty positions. The program will provide independent NCI research support during this transition in order to help awardees to launch competitive, independent research careers.
- NOFO number
- PAR-25-313
- Type
- PAR
- Primary institute
- NCI · National Cancer Institute
- Clinical trials
- Required
- Posted
- Jan 14, 2025
- Opens
- Jan 27, 2025
- Expires
- Oct 15, 2027
PAR-25-313 due dates
3 application due dates remain before the NOFO expires. Dates marked * are NIH standard due dates. Check the related notices below for changes NIH made after posting.
| Application Due Date(s) | Renewal / Resubmission / Revision (as allowed) | AIDS - New/Renewal/Resubmission/Revision, as allowed | Scientific Merit Review | Advisory Council Review | Earliest Start Date |
|---|---|---|---|---|---|
| February 27, 2025 | February 27, 2025 | Not Applicable | July 2025 | October 2025 | December 2025 |
| June 17, 2025 | June 17, 2025 | Not Applicable | November 2025 | January 2026 | April 2026 |
| October 15, 2025 | October 15, 2025 | Not Applicable | March 2026 | May 2026 | July 2026 |
| February 13, 2026 | March 13, 2026 | Not Applicable | July 2026 | October 2026 | December 2026 |
| June 15, 2026 | June 15, 2026 | Not Applicable | November 2026 | January 2027 | April 2027 |
| October 14, 2026 | October 14, 2026 | Not Applicable | March 2027 | May 2027 | July 2027 |
| February 17, 2027 | February 17, 2027 | Not Applicable | July 2027 | October 2027 | December 2027 |
| June 15, 2027 | June 15, 2027 | Not Applicable | November 2027 | January 2028 | April 2028 |
| October 14, 2027 | October 14, 2027 | Not Applicable | March 2028 | May 2028 | July 2028 |
Projects funded under PAR-25-313
NIH RePORTER lists 4 projects funded under PAR-25-313 in FY2022–FY2026, with $580K in award dollars. Counts include each project's later non-competing years, which keep the original NOFO number.
Projects funded
4
Distinct projects, FY2022–FY2026
New awards
4
Type 1 (new project) award records
NIH funding
$580K
Award dollars under PAR-25-313, FY2022–FY2026
Funding by fiscal year
| Fiscal year | Award records | New awards | Funding |
|---|---|---|---|
| FY2022 | 0 | 0 | $0 |
| FY2023 | 0 | 0 | $0 |
| FY2024 | 0 | 0 | $0 |
| FY2025 | 0 | 0 | $0 |
| FY2026 | 4 | 4 | $580K |
Institutions with the most funding
- Adventhealth Orlando$176K · 1 project
- Yale University$155K · 1 project
- University of Rochester$134K · 1 project
- University of Virginia$115K · 1 project
Funding institutes
- NCI$580K · 4
Activity codes funded
- K994 records
Most recent new awards
- Biomarkers of Cancer Risk: Oral Microbiome and Inflammatory Dynamics in Cigarettes and Non-Combustible Nicotine Products (opens NIH RePORTER)
Yale University · 1K99CA315571-01 · NCI · Notice Sep 10, 2026
$155KK99
- A combined exercise and nutrition intervention to treat cancer-related fatigue, unhealthy weight gain, and impaired physical function (opens NIH RePORTER)
University of Rochester · 1K99CA308581-01 · NCI · Notice Jul 6, 2026
$134KK99
- Integrating nutrition and proteomics to improve chemotherapy-induced peripheral neuropathy in cancer survivors (opens NIH RePORTER)
Adventhealth Orlando · 1K99CA308896-01 · NCI · Notice May 7, 2026
$176KK99
- Multilevel, Faith-based Intervention to Promote Rural Physical Activity (opens NIH RePORTER)
University of Virginia · 1K99CA300506-01A1 · NCI · Notice Mar 31, 2026
$115KK99
FY2026 closed on September 30, 2026, but NIH keeps posting that year's awards to RePORTER for several weeks. FY2026 figures reflect records available on October 16, 2026 and may rise slightly at the next refresh.
Participating institutes
2 NIH institutes and offices take applications under PAR-25-313. Contact the program officer at the institute that fits your research before applying.
- NCI · National Cancer Institute
- none
Related notices
Mar 31, 2025 · NOT-OD-24-084
This funding opportunity was updated to align with agency priorities. Carefully reread the full funding opportunity and make any needed adjustments to your application prior to submission.April 4, 2024 - Overview of Grant Application and Review Changes for Due Dates on or after January 25,…
Aug 31, 2022 · NOT-OD-22-198
Implementation Changes for Genomic Data Sharing Plans Included with Applications Due on or after January 25, 2023. See Notice NOT-OD-22-198.
Aug 5, 2022 · NOT-OD-22-189
Implementation Details for the NIH Data Management and Sharing Policy. See Notice NOT-OD-22-189.
Award terms
- Application types allowed
- NewResubmission The OER Glossary and the How to Apply - Application Guide provides details on these application types.
- Award budget
- Information
- Project period
- The total project period may not exceed 5 years. Other
- Funds available and number of awards
- The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications.
Summarized from the NOFO text; the full NOFO governs eligibility, budget, and review.
Related NOFOs
- Companion NOFOs: PAR-25-135.
Other open NOFOs for K99, R00
- PAR-25-135NCI Pathway to Independence Award (K99/R00 Clinical Trial Not Allowed)NCI · next due Feb 17, 2027
- PAR-27-076Lasker Clinical Research Scholar's Program (Si2/R00 Clinical Trial Optional)NIH · next due Nov 6, 2026
- PAR-25-333NIDCR Dual Degree Dentist Scientist Pathway to Independence Award (K99/R00 Clinical Trial Not Allowed)NIDCR · next due Feb 12, 2027
- PA-24-193NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Required)NIH
- PA-24-194NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)NIH
About this page
GotGrant gathers the NOFO, its participation and change notices, and its NOSIs from the NIH Guide for Grants and Contracts, and counts funded projects from NIH RePORTER by the opportunity number each award was made under. Data refreshed October 16, 2026; the NIH Guide is the authoritative source. See our data methodology.