NIH PAR · NCCIH · R01
PAR-25-267: NCCIH Multi-Site Feasibility Clinical Trials of Mind and Body Interventions (R01 Clinical Trial Required)
Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards
This notice of funding opportunity (NOFO) invites applications for investigator-initiated clinical trials of complementary and integrative health approaches with physical and/or psychological therapeutic inputs (often called mind and body interventions) in NCCIH-designated areas of high research priority. Applications submitted under this NOFO are expected to propose a multisite feasibility clinical trial that will provide new information that is scientifically necessary for the planning and conduct of a subsequent clinical efficacy or effectiveness study, pragmatic trial, or dissemination and implementation trial within NCCIHs mission. NCCIH expects that applications to this NOFO will…
- NOFO number
- PAR-25-267
- Type
- PAR
- Activity code
- R01
- Primary institute
- NCCIH · National Center for Complementary and Integrative Health
- Clinical trials
- Required
- Posted
- Nov 21, 2024
- Opens
- Jan 20, 2025
- Expires
- Nov 18, 2026
PAR-25-267 due dates
1 application due date remains before the NOFO expires. Dates marked * are NIH standard due dates. Check the related notices below for changes NIH made after posting.
| Application Due Date(s) | Renewal / Resubmission / Revision (as allowed) | AIDS - New/Renewal/Resubmission/Revision, as allowed | Scientific Merit Review | Advisory Council Review | Earliest Start Date |
|---|---|---|---|---|---|
| February 20, 2025 | February 20, 2025 | March 10, 2025 | July 2025 | October 2025 | December 2025 |
| June 20, 2025 | June 20, 2025 | July 15, 2025 | November 2025 | January 2026 | April 2026 |
| October 20, 2025 | October 20, 2025 | November 18, 2025 | March 2026 | May 2026 | July 2026 |
| February 20, 2026 | February 20, 2026 | March 17, 2026 | July 2026 | October 2026 | December 2026 |
| June 22, 2026 | June 22, 2026 | Not Applicable | November 2026 | January 2027 | April 2027 |
| October 20, 2026 | October 20, 2026 | Not Applicable | March 2027 | May 2027 | July 2027 |
Projects funded under PAR-25-267
NIH RePORTER lists 10 projects funded under PAR-25-267 in FY2022–FY2026, with $12.5M in award dollars. Counts include each project's later non-competing years, which keep the original NOFO number.
Projects funded
10
Distinct projects, FY2022–FY2026
New awards
10
Type 1 (new project) award records
NIH funding
$12.5M
Award dollars under PAR-25-267, FY2022–FY2026
Funding by fiscal year
| Fiscal year | Award records | New awards | Funding |
|---|---|---|---|
| FY2022 | 0 | 0 | $0 |
| FY2023 | 0 | 0 | $0 |
| FY2024 | 0 | 0 | $0 |
| FY2025 | 0 | 0 | $0 |
| FY2026 | 10 | 10 | $12.5M |
Institutions with the most funding
- University of Michigan at Ann Arbor$2.2M · 2 projects
- Butler Hospital (Providence, Ri)$2.1M · 1 project
- Duke University$1.7M · 1 project
- University of Texas Hlth Sci Ctr Houston$1.7M · 1 project
- Brigham and Women's Hospital$1.6M · 1 project
- University of California, San Diego$1.3M · 1 project
- Yale University$635K · 1 project
- Vanderbilt University Medical Center$625K · 1 project
Funding institutes
- NCCIH$12.5M · 10
Activity codes funded
- R0110 records
Most recent new awards
- Multi-site Feasibility Trial of WHEEL, Whole Health for Lupus (opens NIH RePORTER)
Duke University · 1R01AT013961-01 · NCCIH · Notice Sep 17, 2026
$1.7MR01
- Assessing the Feasibility of a Multi-Site.b4me Mindfulness Intervention with Sheltered Homeless Youth (opens NIH RePORTER)
University of Texas Hlth Sci Ctr Houston · 1R01AT013946-01 · NCCIH · Notice Sep 17, 2026
$1.7MR01
- A multi-site feasibility clinical trial of GetHealthy-OA, a mind-body program for those with the combination of knee osteoarthritis, obesity, and depressive symptoms (opens NIH RePORTER)
Brigham and Women's Hospital · 1R01AT013252-01A1 · NCCIH · Notice Sep 17, 2026
$1.6MR01
- Multi-Site Feasibility of Yoga to Enhance Well-Being in Incarcerated Adults (opens NIH RePORTER)
Butler Hospital (Providence, Ri) · 1R01AT014027-01 · NCCIH · Notice Sep 16, 2026
$2.1MR01
- Multi-Site Feasibility Trial of Smartphone-Based Mindfulness Treatment for Promoting Addiction Recovery (opens NIH RePORTER)
Yale University · 1R01AT013980-01 · NCCIH · Notice Sep 1, 2026
$635KR01
- Multicenter Feasibility of Integrative Health Coaching for Back Pain after an Emergency Department Discharge (opens NIH RePORTER)
Vanderbilt University Medical Center · 1R01AT013474-01A1 · NCCIH · Notice Sep 1, 2026
$625KR01
What its predecessor PAR-24-083 funded
PAR-25-267 reissues PAR-24-083. Its funding history is the best guide to who wins under this program: 1 project and $601K in FY2022–FY2026.
Projects funded
1
Distinct projects, FY2022–FY2026
New awards
1
Type 1 (new project) award records
NIH funding
$601K
Award dollars under PAR-24-083, FY2022–FY2026
Funding by fiscal year
| Fiscal year | Award records | New awards | Funding |
|---|---|---|---|
| FY2022 | 0 | 0 | $0 |
| FY2023 | 0 | 0 | $0 |
| FY2024 | 0 | 0 | $0 |
| FY2025 | 0 | 0 | $0 |
| FY2026 | 1 | 1 | $601K |
Institutions with the most funding
- University of California, San Francisco$601K · 1 project
Funding institutes
- NCCIH$601K · 1
Activity codes funded
- R011 record
Most recent new awards
- Assessing multi-site feasibility of an integrated whole-body hyperthermia and behavioral intervention for major depressive disorder (opens NIH RePORTER)
University of California, San Francisco · 1R01AT013214-01 · NCCIH · Notice Apr 16, 2026
$601KR01
FY2026 closed on September 30, 2026, but NIH keeps posting that year's awards to RePORTER for several weeks. FY2026 figures reflect records available on October 16, 2026 and may rise slightly at the next refresh.
Participating institutes
2 NIH institutes and offices take applications under PAR-25-267. Contact the program officer at the institute that fits your research before applying.
- NCCIH · National Center for Complementary and Integrative Health
- none
Related notices
Mar 31, 2025 · NOT-OD-24-084
This funding opportunity was updated to align with agency priorities. Carefully reread the full funding opportunity and make any needed adjustments to your application prior to submission.April 4, 2024 - Overview of Grant Application and Review Changes for Due Dates on or after January 25,…
Aug 31, 2022 · NOT-OD-22-198
Implementation Changes for Genomic Data Sharing Plans Included with Applications Due on or after January 25, 2023. See Notice NOT-OD-22-198.
Aug 5, 2022 · NOT-OD-22-189
Implementation Details for the NIH Data Management and Sharing Policy. See Notice NOT-OD-22-189.
Notices of Special Interest (NOSIs)
NIH has attached 4 NOSIs to PAR-25-267; none are active now. A NOSI flags a topic an institute wants to fund through this NOFO.
Award terms
- Application types allowed
- NewResubmission The OER Glossary and the How to Apply Application Guide provide details on these application types. Only those application types listed here are allowed for this NOFO.
- Award budget
- Application budgets are not limited but need to reflect the actual needs of the proposed project. However, it is strongly recommended that applicants not request a budget of more than 350,000 in direct costs per year.
- Project period
- The scope of the project should determine the project period, but it is strongly recommended that applicants do not request a project period of more than 3 years. The maximum project period is 5 years. NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO.
- Funds available and number of awards
-  The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications.
Summarized from the NOFO text; the full NOFO governs eligibility, budget, and review.
Related NOFOs
- Reissue of PAR-24-083.
- Companion NOFOs: PAR-24-275, PAR-24-276, PAR-25-268, PAR-25-274.
Other open NOFOs for R01
- PAR-25-271NCCIH Natural Product Mid Phase Clinical Trial (R01 Clinical Trial Required)NCCIH · next due Oct 20, 2026
- PAR-25-268Investigator Initiated Clinical Trials of Complementary and Integrative Interventions Delivered Remotely or via mHealth (R01 Clinical Trial Required)NCCIH · next due Oct 20, 2026
- PAR-25-322Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Clinical Trial Not Allowed)OD · next due Jan 26, 2027
- PA-25-301NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed)NIH · next due Feb 5, 2027
- PA-25-305NIH Research Project Grant (Parent R01 Clinical Trial Required)NIH · next due Feb 5, 2027
- PAR-25-144Dissemination and Implementation Research in Health (R01 Clinical Trial Optional)NCI · next due Feb 5, 2027
About this page
GotGrant gathers the NOFO, its participation and change notices, and its NOSIs from the NIH Guide for Grants and Contracts, and counts funded projects from NIH RePORTER by the opportunity number each award was made under. Data refreshed October 16, 2026; the NIH Guide is the authoritative source. See our data methodology.