NIH funding profile · Irvine, CA · Higher education
University of California, Irvine NIH Funding
Also known as UC Irvine, UCINIH RePORTER recipient name: University of California-Irvine
Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards
University of California, Irvine received $225.1M in NIH award funding in fiscal year 2026 across 391 award records and 392 principal investigators. That ranks #42 of 2,407 NIH-funded institutions and #7 in California, down 4.6% from FY2025.
Part of University of California. See its combined NIH funding across every member NIH records separately.
FY2026 closed on September 30, 2026, but NIH keeps posting that year's awards to RePORTER for several weeks. FY2026 figures reflect records available on October 16, 2026 and may rise slightly at the next refresh.
FY2026 NIH funding
$225.1M
−4.6% vs FY2025
National rank
#42
Unchanged vs FY2025
Rank in California
#7
4.5% of California NIH funding
Awards · PIs
391
392 investigators · 83 new projects
NIH funding trend, FY2022–FY2026
University of California, Irvine received $1.14B in NIH awards over these five fiscal years. Annual funding moved +6.8% from FY2022 to FY2026. Its best national rank in the period was #40 (FY2024).
NIH institutes funding University of California, Irvine, FY2026
25 NIH institutes and centers administered awards here in FY2026. The largest, the National Institute on Aging (NIA), accounted for 22.5% of the institution's NIH funding across 45 awards.
- NIA · National Institute on Aging$50.7M · 22.5%
45 awards · vs FY2025: +0.3%
- NCI · National Cancer Institute$23.5M · 10.4%
42 awards · vs FY2025: +1.5%
- NIGMS · National Institute of General Medical Sciences$21.9M · 9.7%
53 awards · vs FY2025: −18.3%
- NIAID · National Institute of Allergy and Infectious Diseases$19.6M · 8.7%
44 awards · vs FY2025: −18.7%
- NEI · National Eye Institute$15.3M · 6.8%
31 awards · vs FY2025: +3.8%
- NINDS · National Institute of Neurological Disorders and Stroke$15.0M · 6.7%
33 awards · vs FY2025: −9.0%
- NHLBI · National Heart, Lung, and Blood Institute$10.0M · 4.4%
26 awards · vs FY2025: +6.9%
- OD · NIH Office of the Director$8.8M · 3.9%
3 awards · vs FY2025: +156.8%
- NCATS · National Center for Advancing Translational Sciences$8.4M · 3.7%
5 awards · vs FY2025: +72.3%
- NIDA · National Institute on Drug Abuse$7.8M · 3.5%
16 awards · vs FY2025: −21.7%
Also: NIDDK $7.7M · NICHD $7.0M · NIMH $5.8M · NHGRI $5.0M · NIAMS $4.6M · NCCIH $3.7M · NIDCD $2.0M · NIEHS $1.9M · NIMHD $1.9M · NIDCR $1.2M · NIBIB $1.2M · NINR $801K · NIAAA $687K · FIC $298K · NLM $155K
Award mechanism mix
Share of NIH award dollars by activity-code family in FY2026, with the FY2022 share for comparison. R01-equivalent research grants were 56.8% of funding.
- R01-equivalent56.8% · FY22 58.2%
- Other research (R)15.5% · FY22 13.8%
- Cooperative agreements (U)14.2% · FY22 15.3%
- Centers & program projects (P)5.2% · FY22 5.7%
- Institutional training (T)2.7% · FY22 2.6%
- Other2.0% · FY22 1.1%
- Career development (K)1.6% · FY22 1.2%
- Contracts (N)1.2% · FY22 1.3%
- Fellowships (F)0.7% · FY22 0.8%
Top activity codes, FY2026
| Code | Awards | Funding | Share | Average award |
|---|---|---|---|---|
| R01 | 188 | $113.1M | 50.3% | $602K |
| R35 | 42 | $18.3M | 8.1% | $437K |
| U54 | 2 | $11.1M | 4.9% | $5.6M |
| RF1 | 2 | $8.7M | 3.9% | $4.3M |
| P30 | 3 | $7.4M | 3.3% | $2.5M |
| U01 | 7 | $7.2M | 3.2% | $1.0M |
| R21 | 21 | $6.6M | 2.9% | $315K |
| UM1 | 2 | $6.4M | 2.9% | $3.2M |
| T32 | 17 | $5.0M | 2.2% | $292K |
| RC2 | 2 | $4.5M | 2.0% | $2.3M |
| OT2 | 1 | $4.2M | 1.9% | $4.2M |
| U19 | 4 | $3.1M | 1.4% | $782K |
Largest FY2026 awards
The biggest single award records by FY2026 dollars. Each links to its NIH RePORTER project page.
- UC Irvine MODEL-AD (opens NIH RePORTER)
5U54AG054349-10 · NIA
$9.3MU54
- Neurobiological basis for dementia in adults with Down syndrome (opens NIH RePORTER)
1RF1AG098213-01 · NIA
$6.1MRF1
- The Alzheimer's Disease Research Center at the University of California, Irvine (opens NIH RePORTER)
5P30AG066519-07 · NIA
$4.3MP30
- All of Us Southern California Consortium (AoUSCC) (opens NIH RePORTER)
3OT2OD036428-01S3 · OD
$4.2MOT2
- Institute for Clinical and Translational Science (opens NIH RePORTER)
5UM1TR004927-03 · NCATS
$4.1MUM1
- Discovery and Trial Ready Cohort for Limbic Predominant Age Related TDP-43 Encephalopathy (TRC LATE) (opens NIH RePORTER)
5R01AG095017-02 · NIA
$3.2MR01
Recently started projects
The latest new (Type 1) FY2026 awards by notice date, out of 83 new projects NIH funded here this year.
- Evaluation of a community co-developed intervention focused on quality of life in Spanish-speaking families impacted by childhood cancer (opens NIH RePORTER)
1R01NR022176-01A1 · NINR · Notice Sep 18, 2026
$801KR01
- The impact of sex hormones on neural mechanisms of sleep-dependent memory during the reproductive age and menopause transition (opens NIH RePORTER)
1R01AG092608-01A1 · NIA · Notice Sep 17, 2026
$779KR01
- Structurally Programmed Microfluidic Bioreactors to Manufacture Retinal Organoids for Regenerative Medicine (opens NIH RePORTER)
1R01EY038193-01A1 · NEI · Notice Sep 17, 2026
$741KR01
- Dynamics of CD4+ and CD8+ T Cells to Control Recurrent Ocular Herpes (opens NIH RePORTER)
1R01EY039366-01 · NEI · Notice Sep 17, 2026
$628KR01
- In Vivo Base Editing via Lipid Nanoparticles Targeting the Trabecular Meshwork for Glaucoma Therapy (opens NIH RePORTER)
1R01EY038840-01 · NEI · Notice Sep 17, 2026
$591KR01
- Treg-mediated tolerance of dystrophin immunity (opens NIH RePORTER)
1R56NS147542-01 · NINDS · Notice Sep 17, 2026
$550KR56
Other NIH-funded institutions in California
| # | Institution | Funding |
|---|---|---|
| 3 | University of California San DiegoLa Jolla, CA | $505.9M |
| 4 | University of California, Los AngelesLos Angeles, CA | $462.9M |
| 5 | University of Southern CaliforniaLos Angeles, CA | $367.3M |
| 6 | University of California, DavisDavis, CA | $308.2M |
| 7 | University of California, IrvineIrvine, CA | $225.1M |
| 8 | Scripps ResearchLa Jolla, CA | $155.5M |
| 9 | University of California, BerkeleyBerkeley, CA | $138.8M |
| 10 | Cedars-Sinai Medical CenterLos Angeles, CA | $119.2M |
| 11 | Kaiser Foundation Research InstituteOakland, CA | $98.9M |
Nearby in the national ranking
| # | Institution | Funding |
|---|---|---|
| 39 | Indiana University IndianapolisIndianapolis, IN | $251.9M |
| 40 | University of VirginiaCharlottesville, VA | $237.1M |
| 41 | Sloan Kettering Institute for Cancer ResearchNew York, NY | $231.1M |
| 42 | University of California, IrvineIrvine, CA | $225.1M |
| 43 | Rutgers Biomedical and Health SciencesNewark, NJ | $212.1M |
| 44 | Children's Hospital of PhiladelphiaPhiladelphia, PA | $202.9M |
| 45 | University of Texas MD Anderson Cancer CenterHouston, TX | $201.8M |
Similar universities and medical schools
| # | Institution | Funding |
|---|---|---|
| 37 | University of UtahSalt Lake City, UT | $277.9M |
| 39 | Indiana University IndianapolisIndianapolis, IN | $251.9M |
| 40 | University of VirginiaCharlottesville, VA | $237.1M |
| 42 | University of California, IrvineIrvine, CA | $225.1M |
| 43 | Rutgers Biomedical and Health SciencesNewark, NJ | $212.1M |
| 46 | University of Maryland, BaltimoreBaltimore, MD | $199.4M |
| 47 | University of RochesterRochester, NY | $197.5M |
About these numbers
Source: the public NIH RePORTER API, refreshed October 16, 2026. See our data methodology and the guide to reading NIH funding rankings by university.
- Who is countedAwards made to NIH recipient organization code 577504 (University of California-Irvine). A university's medical school, affiliated hospital, or other campuses can be separate NIH recipients with their own totals.
- What is countedTotal award amount (direct plus indirect) obligated in each fiscal year for grants, cooperative agreements, training awards, SBIR/STTR, and R&D contracts. Subprojects, intramural research, and interagency agreements are excluded.
- InstitutesEach award is credited in full to its administering institute, even when other institutes co-fund it.
- SubawardsNIH reports the prime recipient only, so research this institution performs under another organization's grant is not included here.