NIH funding profile · Houston, TX · Nonprofit
Houston Methodist Research Institute NIH Funding
NIH RePORTER recipient name: Methodist Hospital Research Institute
Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards
Houston Methodist Research Institute received $42.8M in NIH award funding in fiscal year 2026 across 75 award records and 76 principal investigators. That ranks #160 of 2,407 NIH-funded institutions and #11 in Texas, down 14.3% from FY2025.
FY2026 closed on September 30, 2026, but NIH keeps posting that year's awards to RePORTER for several weeks. FY2026 figures reflect records available on October 16, 2026 and may rise slightly at the next refresh.
FY2026 NIH funding
$42.8M
−14.3% vs FY2025
National rank
#160
Down 14 places from #146 vs FY2025
Rank in Texas
#11
2.3% of Texas NIH funding · down 2 places from #9
Awards · PIs
75
76 investigators · 14 new projects
NIH funding trend, FY2022–FY2026
Houston Methodist Research Institute received $214.5M in NIH awards over these five fiscal years. Annual funding moved +31.2% from FY2022 to FY2026. Its best national rank in the period was #142 (FY2024).
NIH institutes funding Houston Methodist Research Institute, FY2026
10 NIH institutes and centers administered awards here in FY2026. The largest, the National Cancer Institute (NCI), accounted for 33.8% of the institution's NIH funding across 24 awards.
- NCI · National Cancer Institute$14.5M · 33.8%
24 awards · vs FY2025: +3.7%
- NIAID · National Institute of Allergy and Infectious Diseases$10.7M · 25.0%
20 awards · vs FY2025: −43.5%
- NHLBI · National Heart, Lung, and Blood Institute$8.0M · 18.6%
10 awards · vs FY2025: +30.2%
- NINDS · National Institute of Neurological Disorders and Stroke$3.5M · 8.1%
8 awards · vs FY2025: −11.2%
- NIDDK · National Institute of Diabetes and Digestive and Kidney Diseases$2.3M · 5.3%
5 awards · vs FY2025: +13.4%
- NIA · National Institute on Aging$1.5M · 3.6%
3 awards · vs FY2025: −32.9%
- NEI · National Eye Institute$1.3M · 2.9%
2 awards · vs FY2025: +163.7%
- NIAAA · National Institute on Alcohol Abuse and Alcoholism$404K · 0.9%
1 award · vs FY2025: +0.6%
- NIGMS · National Institute of General Medical Sciences$404K · 0.9%
1 award · vs FY2025: 0.0%
- NIDCR · National Institute of Dental and Craniofacial Research$363K · 0.8%
1 award · vs FY2025: −41.7%
Award mechanism mix
Share of NIH award dollars by activity-code family in FY2026, with the FY2022 share for comparison. R01-equivalent research grants were 83.1% of funding.
- R01-equivalent83.1% · FY22 70.2%
- Other research (R)9.3% · FY22 11.0%
- Cooperative agreements (U)4.8% · FY22 9.0%
- Career development (K)1.5% · FY22 1.9%
- Institutional training (T)1.3% · FY22 0.5%
- Centers & program projects (P)0.0% · FY22 7.4%
Top activity codes, FY2026
| Code | Awards | Funding | Share | Average award |
|---|---|---|---|---|
| R01 | 55 | $34.6M | 80.7% | $629K |
| U54 | 1 | $1.7M | 3.9% | $1.7M |
| R21 | 6 | $1.5M | 3.4% | $243K |
| R56 | 1 | $1.0M | 2.4% | $1.0M |
| R24 | 1 | $813K | 1.9% | $813K |
| R33 | 1 | $691K | 1.6% | $691K |
| T32 | 2 | $571K | 1.3% | $286K |
| R35 | 1 | $404K | 0.9% | $404K |
| U01 | 1 | $367K | 0.9% | $367K |
| K76 | 1 | $243K | 0.6% | $243K |
| R00 | 1 | $224K | 0.5% | $224K |
| R61 | 1 | $222K | 0.5% | $222K |
Largest FY2026 awards
The biggest single award records by FY2026 dollars. Each links to its NIH RePORTER project page.
- Deciphering the activation mechanisms and immune functions of GSDMC (opens NIH RePORTER)
1R01AI190307-01A1 · NIAID
$2.5MR01
- Mechanisms of JAG1-mediated immune suppression in the pancreatic cancer microenvironment (opens NIH RePORTER)
4R01CA294584-03 · NCI
$2.0MR01
- Sudden Death Risk Assessment and Mechanistic Insights in Arrhythmic Mitral Valve Prolapse Using Cardiac MRI and Circulating Proteomic Biomarkers (opens NIH RePORTER)
5R01HL171150-03 · NHLBI
$1.8MR01
- The stromal microenvironment as a co-organizer of bladder carcinogenesis and progression (opens NIH RePORTER)
5U54CA274375-05 · NCI
$1.7MU54
- Sirtuin -Dependent Regulation of Tuberculosis and HIV Interactions in Macrophages (opens NIH RePORTER)
5R01AI184551-03 · NIAID
$1.2MR01
- Mitochondrial factories for AMD therapy (opens NIH RePORTER)
1R56EY036406-01A1 · NEI
$1.0MR56
Recently started projects
The latest new (Type 1) FY2026 awards by notice date, out of 14 new projects NIH funded here this year.
- Non-Invasive Detection of Liver Fibrosis Utilizing the MASML Machine Learning Algorithm (opens NIH RePORTER)
1R01DK143254-01A1 · NIDDK · Notice Sep 17, 2026
$440KR01
- Mechanistic role of GPR6 in therapy resistance and its antibody-based targeting in prostate cancer (opens NIH RePORTER)
1R01CA317755-01 · NCI · Notice Sep 16, 2026
$511KR01
- Targeting Mitochondrial DNA Repair Defects in FUS-Associated ALS via Neuron-Specific DNA Ligase I Replacement (opens NIH RePORTER)
1R03NS153153-01 · NINDS · Notice Sep 10, 2026
$162KR03
- The role of GRK3-HDAC2 epigenetic pathway in neuroendocrine prostate cancer and immune evasion (opens NIH RePORTER)
1R01CA315906-01 · NCI · Notice Sep 9, 2026
$515KR01
- Identification of Age and Sex Dependent Contributions to Supraspinal Mechanisms Involved in Underactive Bladder (opens NIH RePORTER)
1R01AG094133-01A1 · NIA · Notice Sep 3, 2026
$666KR01
- Importance of Muscle-Specific E3 Ligase TRIM55 in Autoimmune Myocarditis (opens NIH RePORTER)
1R01HL182780-01A1 · NHLBI · Notice Aug 25, 2026
$756KR01
Other NIH-funded institutions in Texas
| # | Institution | Funding |
|---|---|---|
| 7 | University of Texas Medical Branch at GalvestonGalveston, TX | $103.3M |
| 8 | University of North Texas Health Science CenterFort Worth, TX | $45.4M |
| 9 | University of HoustonHouston, TX | $44.6M |
| 10 | University of Texas at DallasRichardson, TX | $44.3M |
| 11 | Houston Methodist Research InstituteHouston, TX | $42.8M |
| 12 | Texas A&M University Health Science CenterCollege Station, TX | $37.9M |
| 13 | Texas Biomedical Research InstituteSan Antonio, TX | $28.8M |
| 14 | Rice UniversityHouston, TX | $26.3M |
| 15 | Texas A&M UniversityCollege Station, TX | $25.8M |
Nearby in the national ranking
| # | Institution | Funding |
|---|---|---|
| 157 | University of HoustonHouston, TX | $44.6M |
| 158 | University of Texas at DallasRichardson, TX | $44.3M |
| 159 | Rutgers, The State University of New JerseyPiscataway, NJ | $43.3M |
| 160 | Houston Methodist Research InstituteHouston, TX | $42.8M |
| 161 | Oklahoma Medical Research FoundationOklahoma City, OK | $42.7M |
| 162 | Massachusetts Eye and Ear InfirmaryBoston, MA | $42.0M |
| 163 | Cog Research Foundation, LLCArcadia, CA | $41.6M |
Similar research institutes and nonprofits
| # | Institution | Funding |
|---|---|---|
| 151 | Feinstein Institute for Medical ResearchManhasset, NY | $46.6M |
| 155 | Gladstone InstitutesSan Francisco, CA | $45.4M |
| 160 | Houston Methodist Research InstituteHouston, TX | $42.8M |
| 161 | Oklahoma Medical Research FoundationOklahoma City, OK | $42.7M |
| 163 | Cog Research Foundation, LLCArcadia, CA | $41.6M |
| 166 | Family Health InternationalDurham, NC | $40.1M |
| 168 | Cold Spring Harbor LaboratoryCold Spring Harbor, NY | $39.9M |
About these numbers
Source: the public NIH RePORTER API, refreshed October 16, 2026. See our data methodology and the guide to reading NIH funding rankings by university.
- Who is countedAwards made to NIH recipient organization code 10005742 (Methodist Hospital Research Institute). A university's medical school, affiliated hospital, or other campuses can be separate NIH recipients with their own totals.
- What is countedTotal award amount (direct plus indirect) obligated in each fiscal year for grants, cooperative agreements, training awards, SBIR/STTR, and R&D contracts. Subprojects, intramural research, and interagency agreements are excluded.
- InstitutesEach award is credited in full to its administering institute, even when other institutes co-fund it.
- SubawardsNIH reports the prime recipient only, so research this institution performs under another organization's grant is not included here.