NIH RFA · NIDDK · U01
RFA-DK-27-125: Limited Competition for the Continuation of the Caring for OutPatiEnts after Acute Kidney Injury (COPE-AKI) Clinical Centers (U01 Clinical Trial Required)
Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards
This is a Notice of Funding Opportunity (NOFO) for a Limited Competition that will invite application(s) from eligible organization(s) to apply. Please see Section III. Eligibility for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered for funding. This NOFO requests limited competition applications for a 3-year extension of the COPE-AKI clinical trial consortium, which includes three clinical centers (CCs) and one scientific and data research center (SDRC), to fully meet the enrollment targets, complete participant follow-up, and provide resources for data analysis…
- NOFO number
- RFA-DK-27-125
- Type
- RFA
- Activity code
- U01
- Primary institute
- NIDDK · National Institute of Diabetes and Digestive and Kidney Diseases
- Clinical trials
- Required
- Posted
- Aug 31, 2026
- Opens
- Oct 6, 2026
- Expires
- Nov 7, 2026
RFA-DK-27-125 due dates
1 application due date remains before the NOFO expires. Dates marked * are NIH standard due dates. Check the related notices below for changes NIH made after posting.
| New | Renewal / Resubmission / Revision (as allowed) | AIDS - New/Renewal/Resubmission/Revision, as allowed | Scientific Merit Review | Advisory Council Review | Earliest Start Date |
|---|---|---|---|---|---|
| Not Applicable | November 06, 2026 | Not Applicable | March 2027 | May 2027 | July 2027 |
What its predecessor RFA-DK-20-011 funded
RFA-DK-27-125 reissues RFA-DK-20-011. Until awards appear under the new number, its funding history is the best guide to who wins under this program: 3 projects and $10.8M in FY2022–FY2026.
Projects funded
3
Distinct projects, FY2022–FY2026
New awards
0
Type 1 (new project) award records
NIH funding
$10.8M
Award dollars under RFA-DK-20-011, FY2022–FY2026
Funding by fiscal year
| Fiscal year | Award records | New awards | Funding |
|---|---|---|---|
| FY2022 | 3 | 0 | $2.0M |
| FY2023 | 3 | 0 | $1.9M |
| FY2024 | 3 | 0 | $1.9M |
| FY2025 | 3 | 0 | $2.5M |
| FY2026 | 3 | 0 | $2.4M |
Institutions with the most funding
- Vanderbilt University Medical Center$4.1M · 1 project
- Cleveland Clinic Lerner Com-Cwru$3.4M · 1 project
- Johns Hopkins University$3.3M · 1 project
Funding institutes
- NIDDK$10.8M · 15
Activity codes funded
- U0115 records
FY2026 closed on September 30, 2026, but NIH keeps posting that year's awards to RePORTER for several weeks. FY2026 figures reflect records available on October 16, 2026 and may rise slightly at the next refresh.
Participating institutes
2 NIH institutes and offices take applications under RFA-DK-27-125. Contact the program officer at the institute that fits your research before applying.
- NIDDK · National Institute of Diabetes and Digestive and Kidney Diseases
- none
Related notices
NIH lists no related notices for RFA-DK-27-125 yet.
Award terms
- Application types allowed
- Renewal The OER Glossary and the How to Apply Application Guide provide details on these application types. Only those application types listed here are allowed for this NOFO.
- Award budget
- Application budgets are not limited but need to reflect the actual needs of the proposed project.
- Project period
- The scope of the proposed project should determine the project period. The maximum project period is 3 years. NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO.
- Funds available and number of awards
- NIDDK intends to commit 1.85M direct costs in FY2027 to fund approximately 3 awards.
Summarized from the NOFO text; the full NOFO governs eligibility, budget, and review.
Related NOFOs
- Reissue of RFA-DK-20-011.
- Companion NOFOs: RFA-DK-27-139.
Other open NOFOs for U01
- RFA-DK-27-112Single Source for the Continuation of the Epidemiology of Diabetes Interventions and Complications (EDIC) Study Research Center (Collaborative U01 Clinical Trial Not Allowed)NIDDK · next due Nov 9, 2026
- RFA-DK-27-139Single Source for the Continuation of the Caring for OutPatiEnts after Acute Kidney Injury (COPE-AKI) Scientific and Data Research Center (U01 Clinical Trial Required)NIDDK · next due Nov 9, 2026
- RFA-DK-27-122Single Source for the Continuation of the Physiology of the Weight Reduced State (POWERS) Study (U01- Clinical Trials Required)NIDDK · next due Nov 17, 2026
- RFA-DK-27-108Continuation of the Cardiovascular Repository for-Type 1 Diabetes (CARE-T1D) Consortium U01 (Open Competition)- Research (U01, Clinical Trial Not Allowed)NIDDK · next due Feb 10, 2027
- RFA-CA-27-019Early-Stage Development of Informatics Technologies for Cancer Research and Management (U01 Clinical Trial Optional)NCI · next due Oct 19, 2026
- RFA-DE-27-001Community Engagement Evaluation and Data Coordination (CEED) Hub to Advance Data and Practice Transformation for Optimizing Oral Health for All (U01, Clinical Trial Not Allowed)NIDCR · next due Oct 19, 2026
About this page
GotGrant gathers the NOFO, its participation and change notices, and its NOSIs from the NIH Guide for Grants and Contracts, and counts funded projects from NIH RePORTER by the opportunity number each award was made under. Data refreshed October 16, 2026; the NIH Guide is the authoritative source. See our data methodology.