NIH RFA · NIDDK · U01

RFA-DK-27-108: Continuation of the Cardiovascular Repository for-Type 1 Diabetes (CARE-T1D) Consortium U01 (Open Competition)- Research (U01, Clinical Trial Not Allowed)

Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards

Open for applicationsNext due date: Feb 10, 2027Expires Mar 11, 2027

The NIH Cardiovascular Repository for Type 1 Diabetes (CaRe-T1D) was created to improve research on type 1 diabetes (T1D) and cardiovascular disease (CVD). Cardiovascular complications remain the top cause of death among people with T1D and greatly shorten lifespan. The mechanisms underlying atherosclerosis, cardiomyopathy, endothelial dysfunction, and cardiac autonomic neuropathy in T1D remain poorly understood. While managing traditional risk factors—such as high blood glucose, high blood pressure, and elevated cholesterol lower cardiovascular risk, a significant residual risk remains even with optimal control. In addition to atherosclerosis, both diastolic and systolic diabetic…

Full NOFO in the NIH Guide Apply on Grants.gov

NOFO number
RFA-DK-27-108
Type
RFA
Activity code
U01
Primary institute
NIDDK · National Institute of Diabetes and Digestive and Kidney Diseases
Clinical trials
Not Allowed
Posted
Jun 4, 2026
Opens
Sep 9, 2026
Expires
Mar 11, 2027

RFA-DK-27-108 due dates

1 application due date remains before the NOFO expires. Dates marked * are NIH standard due dates. Check the related notices below for changes NIH made after posting.

Application due dates and review cycles for RFA-DK-27-108
NewRenewal / Resubmission / Revision (as allowed)AIDS - New/Renewal/Resubmission/Revision, as allowedScientific Merit ReviewAdvisory Council ReviewEarliest Start Date
October 09, 2026November 09, 2026Not ApplicableMarch 2027May 2027July 2027
February 10, 2027March 10, 2027Not ApplicableJuly 2027October 2027December 2027

What its predecessor RFA-DK-23-021 funded

RFA-DK-27-108 reissues RFA-DK-23-021. Until awards appear under the new number, its funding history is the best guide to who wins under this program: 6 projects and $17.1M in FY2022–FY2026.

Projects funded

6

Distinct projects, FY2022–FY2026

New awards

6

Type 1 (new project) award records

NIH funding

$17.1M

Award dollars under RFA-DK-23-021, FY2022–FY2026

Funding by fiscal year

Award records, new awards, and funding by fiscal year under RFA-DK-23-021
Fiscal yearAward recordsNew awardsFunding
FY202200$0
FY202300$0
FY202466$5.8M
FY202560$5.8M
FY202660$5.6M

Institutions with the most funding

  1. University of Washington$3.2M · 1 project
  2. Brigham and Women's Hospital$3.1M · 1 project
  3. University of California, San Diego$3.0M · 1 project
  4. Joslin Diabetes Center$2.9M · 1 project
  5. University of Virginia$2.9M · 1 project
  6. West Virginia University$2.2M · 1 project

Funding institutes

  • NIDDK$17.1M · 18

Activity codes funded

Most recent new awards

FY2026 closed on September 30, 2026, but NIH keeps posting that year's awards to RePORTER for several weeks. FY2026 figures reflect records available on October 16, 2026 and may rise slightly at the next refresh.

Participating institutes

2 NIH institutes and offices take applications under RFA-DK-27-108. Contact the program officer at the institute that fits your research before applying.

  • NIDDK · National Institute of Diabetes and Digestive and Kidney Diseases
  • NHLBI · National Heart, Lung, and Blood Institute

Related notices

NIH lists no related notices for RFA-DK-27-108 yet.

Award terms

Application types allowed
New Renewal Resubmission The OER Glossary and the How to Apply Application Guide provide details on these application types. Only those application types listed here are allowed for this NOFO.
Award budget
Application budgets are not limited, but need to reflect the actual needs of the proposed project. Application budgets cannot exceed 500K in direct costs in any year. NIDDK expects that the requested direct costs will be 500K based on the scope of the research, plus applicable Facilities and Administrative costs to be determined at the time of the award.
Project period
The scope of the proposed project should determine the project period. The maximum project period is three years. NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO.
Funds available and number of awards
A total of six to eight grants will be awarded in FY 2027 and FY 2028. 500K Direct Costs)-per year for three years. Total available funds: 6 million.

Summarized from the NOFO text; the full NOFO governs eligibility, budget, and review.

Related NOFOs

  • Reissue of RFA-DK-23-021.
  • Companion NOFOs: RFA-DK-27-109.

Other open NOFOs for U01

Browse all open NIH NOFOs

About this page

GotGrant gathers the NOFO, its participation and change notices, and its NOSIs from the NIH Guide for Grants and Contracts, and counts funded projects from NIH RePORTER by the opportunity number each award was made under. Data refreshed October 16, 2026; the NIH Guide is the authoritative source. See our data methodology.

Find who wins under this NOFO

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