NIH RFA · NIDDK · U01
RFA-DK-27-112: Single Source for the Continuation of the Epidemiology of Diabetes Interventions and Complications (EDIC) Study Research Center (Collaborative U01 Clinical Trial Not Allowed)
Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards
This is a Notice of Funding Opportunity (NOFO) for a Single Source that will invite an application from the eligible organization to apply. Please see Section III. Eligibility for additional information. In accordance with NIH standard peer-review processes, applications will be peer-reviewed, and only meritorious applications will be considered for funding. Through this NOFO, the National institute of Diabetes and Digestive and Kidney Diseases (NIDDK) invites an application to continue to follow the Epidemiology of Diabetes Interventions and Complications (EDIC) cohort through a collaborative cooperative agreement that addresses specific knowledge gaps in the development and progression of…
- NOFO number
- RFA-DK-27-112
- Type
- RFA
- Activity code
- U01
- Primary institute
- NIDDK · National Institute of Diabetes and Digestive and Kidney Diseases
- Clinical trials
- Not Allowed
- Posted
- Aug 31, 2026
- Opens
- Oct 9, 2026
- Expires
- Nov 10, 2026
RFA-DK-27-112 due dates
1 application due date remains before the NOFO expires. Dates marked * are NIH standard due dates. Check the related notices below for changes NIH made after posting.
| New | Renewal / Resubmission / Revision (as allowed) | AIDS - New/Renewal/Resubmission/Revision, as allowed | Scientific Merit Review | Advisory Council Review | Earliest Start Date |
|---|---|---|---|---|---|
| Not Applicable | November 09, 2026 | Not Applicable | March 2027 | May 2027 | July 2027 |
What its predecessor RFA-DK-21-503 funded
RFA-DK-27-112 reissues RFA-DK-21-503. Until awards appear under the new number, its funding history is the best guide to who wins under this program: 1 project and $37.4M in FY2022–FY2026.
Projects funded
1
Distinct projects, FY2022–FY2026
New awards
0
Type 1 (new project) award records
NIH funding
$37.4M
Award dollars under RFA-DK-21-503, FY2022–FY2026
Funding by fiscal year
| Fiscal year | Award records | New awards | Funding |
|---|---|---|---|
| FY2022 | 1 | 0 | $6.5M |
| FY2023 | 1 | 0 | $7.7M |
| FY2024 | 1 | 0 | $8.0M |
| FY2025 | 3 | 0 | $8.0M |
| FY2026 | 3 | 0 | $7.2M |
Institutions with the most funding
- Case Western Reserve University$37.4M · 1 project
Funding institutes
- NIDDK$37.4M · 9
Activity codes funded
- U019 records
FY2026 closed on September 30, 2026, but NIH keeps posting that year's awards to RePORTER for several weeks. FY2026 figures reflect records available on October 16, 2026 and may rise slightly at the next refresh.
Participating institutes
2 NIH institutes and offices take applications under RFA-DK-27-112. Contact the program officer at the institute that fits your research before applying.
- NIDDK · National Institute of Diabetes and Digestive and Kidney Diseases
- none
Related notices
NIH lists no related notices for RFA-DK-27-112 yet.
Award terms
- Application types allowed
- Renewal The OER Glossary and the How to Apply Application Guide provide details on these application types. Only those application types listed here are allowed for this NOFO.
- Award budget
- The application budget is limited to 6.3 million per year in direct costs for the entire project period. Budgets should reflect the actual needs of the proposed project..
- Project period
- The maximum project period is 5 years. NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO.
- Funds available and number of awards
- NIDDK intends to commit up to 6.5 million in Fiscal Year 2027 to support the continuation of EDIC under RFA-DK-27-112. It is expected that one award will be made for the Research Center under this NOFO.
Summarized from the NOFO text; the full NOFO governs eligibility, budget, and review.
Related NOFOs
- Reissue of RFA-DK-21-503.
Other open NOFOs for U01
- RFA-DK-27-125Limited Competition for the Continuation of the Caring for OutPatiEnts after Acute Kidney Injury (COPE-AKI) Clinical Centers (U01 Clinical Trial Required)NIDDK · next due Nov 6, 2026
- RFA-DK-27-139Single Source for the Continuation of the Caring for OutPatiEnts after Acute Kidney Injury (COPE-AKI) Scientific and Data Research Center (U01 Clinical Trial Required)NIDDK · next due Nov 9, 2026
- RFA-DK-27-122Single Source for the Continuation of the Physiology of the Weight Reduced State (POWERS) Study (U01- Clinical Trials Required)NIDDK · next due Nov 17, 2026
- RFA-DK-27-108Continuation of the Cardiovascular Repository for-Type 1 Diabetes (CARE-T1D) Consortium U01 (Open Competition)- Research (U01, Clinical Trial Not Allowed)NIDDK · next due Feb 10, 2027
- RFA-CA-27-019Early-Stage Development of Informatics Technologies for Cancer Research and Management (U01 Clinical Trial Optional)NCI · next due Oct 19, 2026
- RFA-DE-27-001Community Engagement Evaluation and Data Coordination (CEED) Hub to Advance Data and Practice Transformation for Optimizing Oral Health for All (U01, Clinical Trial Not Allowed)NIDCR · next due Oct 19, 2026
About this page
GotGrant gathers the NOFO, its participation and change notices, and its NOSIs from the NIH Guide for Grants and Contracts, and counts funded projects from NIH RePORTER by the opportunity number each award was made under. Data refreshed October 16, 2026; the NIH Guide is the authoritative source. See our data methodology.