NIH RFA · NIDA · RM1
RFA-DA-28-011: HEAL Initiative: Integrative Management of Chronic Pain and OUD for Whole Recovery (IMPOWR): Research Centers (RM1 Clinical Trial Required)
Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards
The National Institutes of Health (NIH) intends to renew the Integrative Management of chronic Pain and OUD for Whole Recovery (IMPOWR) research network. This renewed network will include several individual research projects supported by one central Coordination Center. The goal of the network is to test new and improved approaches for people who have both chronic pain (CP) and opioid use disorder (OUD). These approaches should lead to meaningful improvements in how health systems deliver care. The network will be part of the NIH’s Helping to End Addiction Long-term (HEAL®) Initiative to speed the development and implementation of scientific solutions to the national opioid public health…
- NOFO number
- RFA-DA-28-011
- Type
- RFA
- Activity code
- RM1
- Primary institute
- NIDA · National Institute on Drug Abuse
- Clinical trials
- Required
- Posted
- Oct 6, 2026
- Opens
- Dec 26, 2026
- Expires
- Jan 27, 2027
RFA-DA-28-011 due dates
1 application due date remains before the NOFO expires. Dates marked * are NIH standard due dates. Check the related notices below for changes NIH made after posting.
| New | Renewal / Resubmission / Revision (as allowed) | AIDS - New/Renewal/Resubmission/Revision, as allowed | Scientific Merit Review | Advisory Council Review | Earliest Start Date |
|---|---|---|---|---|---|
| January 26, 2027 | Not Applicable | Not Applicable | July 2027 | August 2027 | December 2027 |
What its predecessor RFA-DA-21-030 funded
RFA-DA-28-011 reissues RFA-DA-21-030. Until awards appear under the new number, its funding history is the best guide to who wins under this program: 4 projects and $27.8M in FY2022–FY2026.
Projects funded
4
Distinct projects, FY2022–FY2026
New awards
0
Type 1 (new project) award records
NIH funding
$27.8M
Award dollars under RFA-DA-21-030, FY2022–FY2026
Funding by fiscal year
| Fiscal year | Award records | New awards | Funding |
|---|---|---|---|
| FY2022 | 0 | 0 | $0 |
| FY2023 | 4 | 0 | $9.5M |
| FY2024 | 4 | 0 | $9.1M |
| FY2025 | 4 | 0 | $9.2M |
| FY2026 | 0 | 0 | $0 |
Institutions with the most funding
- University of Pittsburgh at Pittsburgh$7.6M · 1 project
- Albert Einstein College of Medicine$7.3M · 1 project
- Yale University$6.9M · 1 project
- University of New Mexico$6.1M · 1 project
Funding institutes
- NIDA$27.8M · 12
Activity codes funded
- RM112 records
FY2026 closed on September 30, 2026, but NIH keeps posting that year's awards to RePORTER for several weeks. FY2026 figures reflect records available on October 16, 2026 and may rise slightly at the next refresh.
Participating institutes
5 NIH institutes and offices take applications under RFA-DA-28-011. Contact the program officer at the institute that fits your research before applying.
- NIDA · National Institute on Drug Abuse
- NIA · National Institute on Aging
- NIAAA · National Institute on Alcohol Abuse and Alcoholism
- NINDS · National Institute of Neurological Disorders and Stroke
- NCCIH · National Center for Complementary and Integrative Health
Related notices
NIH lists no related notices for RFA-DA-28-011 yet.
Award terms
- Application types allowed
- New Renewal The OER Glossary and the How to Apply - Application Guide provide details on these application types. Only those application types listed here are allowed for this NOFO.
- Award budget
- Direct costs are limited to 900,000 per year over the 5-year project period.
- Project period
- The maximum project period is 5 years. NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO.
- Funds available and number of awards
- The HEAL Initiative intends to commit 12,000,000 in FY 2027 to fund six-eight awards.
Summarized from the NOFO text; the full NOFO governs eligibility, budget, and review.
Related NOFOs
- Reissue of RFA-DA-21-030.
- Companion NOFOs: RFA-DA-28-012.
Other open NOFOs for RM1
- RFA-DA-25-060High Priority HIV and Substance Use Research (RM1 Clinical Trial Optional)NIDA
- PAR-27-003Collaborative Program Grant for Interdisciplinary Teams (RM1 Clinical Trial Optional)NIGMS · next due Nov 17, 2026
- RFA-NS-27-002BRAIN Initiative: Integrative Team-Research BRAIN Circuits Program - iBCP (RM1 Clinical Trial Not Allowed)NINDS · next due Jun 23, 2027
- PAR-27-024Biomedical Technology Optimization and Dissemination Center (BTOD) (RM1 - Clinical Trial Not Allowed)NIGMS · next due Jan 28, 2027
About this page
GotGrant gathers the NOFO, its participation and change notices, and its NOSIs from the NIH Guide for Grants and Contracts, and counts funded projects from NIH RePORTER by the opportunity number each award was made under. Data refreshed October 16, 2026; the NIH Guide is the authoritative source. See our data methodology.