NIH PAR · NIGMS · RM1
PAR-27-003: Collaborative Program Grant for Interdisciplinary Teams (RM1 Clinical Trial Optional)
Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards
This Notice of Funding Opportunity (NOFO) supports interdisciplinary research teams of three to six Program Directors/Principal Investigators (PDs/PIs) to address ambitious and challenging research questions. Collaborative program teams are expected to be integrated, working together to tackle a single focused scientific goal that requires considerable synergy and meaningful team interaction. Program goals should not be achievable through individual efforts or a collection of projects. Teams are encouraged to consider far-reaching objectives that will produce major advances in their fields.
- NOFO number
- PAR-27-003
- Type
- PAR
- Activity code
- RM1
- Primary institute
- NIGMS · National Institute of General Medical Sciences
- Clinical trials
- Optional
- Posted
- Oct 14, 2026
- Opens
- Oct 17, 2026
- Expires
- Sep 27, 2029
PAR-27-003 due dates
10 application due dates remain before the NOFO expires. Dates marked * are NIH standard due dates. Check the related notices below for changes NIH made after posting.
| New | Renewal / Resubmission / Revision (as allowed) | AIDS - New/Renewal/Resubmission/Revision, as allowed | Scientific Merit Review | Advisory Council Review | Earliest Start Date |
|---|---|---|---|---|---|
| November 17, 2026 | November 17, 2026 | Not Applicable | March 2027 | May 2027 | July 2027 |
| January 26, 2027 | January 26, 2027 | Not Applicable | July 2027 | October 2027 | December 2027 |
| May 26, 2027 | May 26, 2027 | Not Applicable | November 2027 | January 2028 | April 2028 |
| September 27, 2027 | September 27, 2027 | Not Applicable | March 2028 | May 2028 | July 2028 |
| January 26, 2028 | January 26, 2028 | Not Applicable | July 2028 | October 2028 | December 2028 |
| May 26, 2028 | May 26, 2028 | Not Applicable | November 2028 | January 2029 | April 2029 |
| September 26, 2028 | September 26, 2028 | Not Applicable | March 2029 | May 2029 | July 2029 |
| January 26, 2029 | January 26, 2029 | Not Applicable | July 2029 | October 2029 | December 2029 |
| May 29, 2029 | May 29, 2029 | Not Applicable | November 2029 | January 2030 | April 2030 |
| September 26, 2029 | September 26, 2029 | Not Applicable | March 2030 | May 2030 | July 2030 |
Funded projects
NIH RePORTER lists no awards under PAR-27-003 in FY2022–FY2026, and it is a new NOFO rather than a reissue. Awards usually appear a few months after the first review cycle.
Participating institutes
13 NIH institutes and offices take applications under PAR-27-003. Contact the program officer at the institute that fits your research before applying.
- NIGMS · National Institute of General Medical Sciences
- NEI · National Eye Institute
- NHGRI · National Human Genome Research Institute
- NIA · National Institute on Aging
- NIAAA · National Institute on Alcohol Abuse and Alcoholism
- NIAID · National Institute of Allergy and Infectious Diseases
- NIAMS · National Institute of Arthritis and Musculoskeletal and Skin Diseases
- NIDCD · National Institute on Deafness and Other Communication Disorders
- NIDCR · National Institute of Dental and Craniofacial Research
- NIDA · National Institute on Drug Abuse
- NINDS · National Institute of Neurological Disorders and Stroke
- NLM · National Library of Medicine
- NCCIH · National Center for Complementary and Integrative Health
Related notices
NIH lists no related notices for PAR-27-003 yet.
Award terms
- Application types allowed
- New Renewal Resubmission Revision The OER Glossary and the How to Apply - Application Guide provide details on these application types. Only those application types listed here are allowed for this NOFO.
- Award budget
- Applications may request budgets of up to 1.5 million in direct costs per year; however, most awards are expected to be between 500,000–$900,000 in direct costs annually.
- Project period
- Applications may request up to five years of support. Teams wishing to continue their project beyond 5 years are strongly advised to consult with participating ICs prior to submitting a renewal application. Renewals beyond ten years of total support are not allowed. NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from…
- Funds available and number of awards
- The number of awards is contingent upon NIH appropriations and the receipt of a sufficient number of meritorious applications.
Summarized from the NOFO text; the full NOFO governs eligibility, budget, and review.
Other open NOFOs for RM1
- PAR-27-024Biomedical Technology Optimization and Dissemination Center (BTOD) (RM1 - Clinical Trial Not Allowed)NIGMS · next due Jan 28, 2027
- RFA-DA-28-011HEAL Initiative: Integrative Management of Chronic Pain and OUD for Whole Recovery (IMPOWR): Research Centers (RM1 Clinical Trial Required)NIDA · next due Jan 26, 2027
- RFA-NS-27-002BRAIN Initiative: Integrative Team-Research BRAIN Circuits Program - iBCP (RM1 Clinical Trial Not Allowed)NINDS · next due Jun 23, 2027
- RFA-DA-25-060High Priority HIV and Substance Use Research (RM1 Clinical Trial Optional)NIDA
About this page
GotGrant gathers the NOFO, its participation and change notices, and its NOSIs from the NIH Guide for Grants and Contracts, and counts funded projects from NIH RePORTER by the opportunity number each award was made under. Data refreshed October 16, 2026; the NIH Guide is the authoritative source. See our data methodology.