NIH RFA · NIDA · U2C
RFA-DA-28-012: HEAL Initiative: Integrative Management of chronic Pain and OUD for Whole Recovery (IMPOWR) - Building Engagement, Assistance, Capacity, Outreach, and Networks (BEACON) Center (U2C Clinical Trial Not Allowed)
Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards
The National Institutes of Health (NIH) intends to renew the Integrative Management of chronic Pain and OUD for Whole Recovery (IMPOWR) research network. This renewal consists of individual research projects, which will be supported by a single Coordination Center. This network is intended to test new innovations that integrate evidence based treatments for chronic pain (CP) and opioid use disorder (OUD). This research will characterize or modify factors that impact wide-scale adoption and sustained use of effective treatments at this intersection. The network will be part of the NIH’s Helping to End Addiction Long-term (HEAL®) Initiative to speed the development and implementation of…
- NOFO number
- RFA-DA-28-012
- Type
- RFA
- Activity code
- U2C
- Primary institute
- NIDA · National Institute on Drug Abuse
- Clinical trials
- Not Allowed
- Posted
- Oct 6, 2026
- Opens
- Dec 26, 2026
- Expires
- Jan 27, 2027
RFA-DA-28-012 due dates
1 application due date remains before the NOFO expires. Dates marked * are NIH standard due dates. Check the related notices below for changes NIH made after posting.
| New | Renewal / Resubmission / Revision (as allowed) | AIDS - New/Renewal/Resubmission/Revision, as allowed | Scientific Merit Review | Advisory Council Review | Earliest Start Date |
|---|---|---|---|---|---|
| January 26, 2027 | Not Applicable | Not Applicable | July 2027 | August 2027 | December 2027 |
What its predecessor RFA-DA-21-029 funded
RFA-DA-28-012 reissues RFA-DA-21-029. Until awards appear under the new number, its funding history is the best guide to who wins under this program: 1 project and $1.8M in FY2022–FY2026.
Projects funded
1
Distinct projects, FY2022–FY2026
New awards
0
Type 1 (new project) award records
NIH funding
$1.8M
Award dollars under RFA-DA-21-029, FY2022–FY2026
Funding by fiscal year
| Fiscal year | Award records | New awards | Funding |
|---|---|---|---|
| FY2022 | 1 | 0 | $1.0M |
| FY2023 | 1 | 0 | $800K |
| FY2024 | 0 | 0 | $0 |
| FY2025 | 0 | 0 | $0 |
| FY2026 | 0 | 0 | $0 |
Institutions with the most funding
- Wake Forest University Health Sciences$1.8M · 1 project
Funding institutes
- NIDA$1.8M · 2
Activity codes funded
- R242 records
FY2026 closed on September 30, 2026, but NIH keeps posting that year's awards to RePORTER for several weeks. FY2026 figures reflect records available on October 16, 2026 and may rise slightly at the next refresh.
Participating institutes
5 NIH institutes and offices take applications under RFA-DA-28-012. Contact the program officer at the institute that fits your research before applying.
- NIDA · National Institute on Drug Abuse
- NIA · National Institute on Aging
- NIAAA · National Institute on Alcohol Abuse and Alcoholism
- NINDS · National Institute of Neurological Disorders and Stroke
- NCCIH · National Center for Complementary and Integrative Health
Related notices
Jan 23, 2026 · NOT-OD-26-031
NIH Pause on New Submissions to the NIH Human Embryonic Stem Cell Registry and Request for Information on Reducing Reliance on Human Embryonic Stem Cells in NIH-Supported Research.
Award terms
- Application types allowed
- New The OER Glossary and the How to Apply - Application Guide provides details on these application types. Only those application types listed here are allowed for this NOFO.
- Award budget
- Application budgets are limited to 1.50 million direct costs per year. Budgets must reflect the actual needs of the proposed project.
- Project period
- The maximum project period is 5 years. NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO.
- Funds available and number of awards
- The NIH HEAL Helping to End Addiction Long-term) Initiative intends to commit an estimated total of 2.5 million to fund one award in FY2027. Awards pursuant to this funding opportunity are contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications
Summarized from the NOFO text; the full NOFO governs eligibility, budget, and review.
Related NOFOs
- Reissue of RFA-DA-21-029.
- Companion NOFOs: RFA-DA-28-011.
Other open NOFOs for U2C
About this page
GotGrant gathers the NOFO, its participation and change notices, and its NOSIs from the NIH Guide for Grants and Contracts, and counts funded projects from NIH RePORTER by the opportunity number each award was made under. Data refreshed October 16, 2026; the NIH Guide is the authoritative source. See our data methodology.