NIH RFA · NHGRI · U01

RFA-HG-27-012: GREGoRi Technology Integration Center (U01, Clinical Trials Optional)

Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards

Open for applicationsNext due date: Oct 30, 2026Expires Oct 31, 2026

The Genomics Research to Elucidate the Genetics of Rare Diseases:innovation (GREGoRi) initiative seeks to accelerate a paradigm shift in rare disease diagnosis by reimagining the tools, molecular technologies and analytical approaches used to identify the causal gene(s) and/or variant(s) underlying rare genetic disorders. The purpose of this Notice of Funding Opportunity is to establish the GREGoRi Technology Integration Center, which will enable the development of standards and best practices for applying new and emerging molecular methods in rare disease diagnosis. A major deliverable of the Center will be a multidimensional dataset that can be used for the development and benchmarking of…

Full NOFO in the NIH Guide Apply on Grants.gov

NOFO number
RFA-HG-27-012
Type
RFA
Activity code
U01
Primary institute
NHGRI · National Human Genome Research Institute
Clinical trials
Optional
Posted
Jun 18, 2026
Opens
Sep 30, 2026
Expires
Oct 31, 2026

RFA-HG-27-012 due dates

1 application due date remains before the NOFO expires. Dates marked * are NIH standard due dates. Check the related notices below for changes NIH made after posting.

Application due dates and review cycles for RFA-HG-27-012
NewRenewal / Resubmission / Revision (as allowed)AIDS - New/Renewal/Resubmission/Revision, as allowedScientific Merit ReviewAdvisory Council ReviewEarliest Start Date
October 30, 2026Not ApplicableNot ApplicableMarch 2027May 2027July 2027

Funded projects

NIH RePORTER lists no awards under RFA-HG-27-012 in FY2022–FY2026, and it is a new NOFO rather than a reissue. Awards usually appear a few months after the first review cycle.

Participating institutes

2 NIH institutes and offices take applications under RFA-HG-27-012. Contact the program officer at the institute that fits your research before applying.

  • NHGRI · National Human Genome Research Institute
  • none

Related notices

NIH lists no related notices for RFA-HG-27-012 yet.

Award terms

Application types allowed
New The OER Glossary and the How to Apply Application Guide provide details on these application types. Only those application types listed here are allowed for this NOFO.
Award budget
Application budgets are limited to 2.25 million in direct costs per project year, and must reflect the actual needs of the proposed project.
Project period
The maximum project period is 5 years. NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO.
Funds available and number of awards
NHGRI intends to commit a total of 3 million in FY 2027 to fund 1 award.

Summarized from the NOFO text; the full NOFO governs eligibility, budget, and review.

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About this page

GotGrant gathers the NOFO, its participation and change notices, and its NOSIs from the NIH Guide for Grants and Contracts, and counts funded projects from NIH RePORTER by the opportunity number each award was made under. Data refreshed October 16, 2026; the NIH Guide is the authoritative source. See our data methodology.

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