NIH RFA · NCI · U01

RFA-CA-27-019: Early-Stage Development of Informatics Technologies for Cancer Research and Management (U01 Clinical Trial Optional)

Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards

Open for applicationsNext due date: Oct 19, 2026Expires Oct 20, 2027

This Notice of Funding Opportunity (NOFO) solicits applications for the development of enabling informatics technologies to improve the acquisition, management, analysis, and dissemination of data and knowledge across the cancer research continuum including cancer biology, cancer treatment and diagnosis, early cancer detection, risk assessment and prevention, cancer control and epidemiology. As a component of the NCI's Informatics Technology for Cancer Research (ITCR) Program, this NOFO is focused on early-stage development from prototyping to initial dissemination. Early-stage development is defined for the purpose of this NOFO as initial tool development or the significant modification of…

Full NOFO in the NIH Guide Apply on Grants.gov

NOFO number
RFA-CA-27-019
Type
RFA
Activity code
U01
Primary institute
NCI · National Cancer Institute
Clinical trials
Optional
Posted
May 21, 2026
Opens
Jun 1, 2026
Expires
Oct 20, 2027

RFA-CA-27-019 due dates

3 application due dates remain before the NOFO expires. Dates marked * are NIH standard due dates. Check the related notices below for changes NIH made after posting.

Application due dates and review cycles for RFA-CA-27-019
NewRenewal / Resubmission / Revision (as allowed)AIDS - New/Renewal/Resubmission/Revision, as allowedScientific Merit ReviewAdvisory Council ReviewEarliest Start Date
July 01, 2026July 01, 2026Not ApplicableNovember 2026January 2027April 2027
October 19, 2026October 19, 2026Not ApplicableMarch 2027May 2027July 2027
June 11, 2027June 11, 2027Not ApplicableNovember 2027January 2028April 2028
October 19, 2027October 19, 2027Not ApplicableMarch 2028May 2028July 2028

What its predecessor RFA-CA-24-017 funded

RFA-CA-27-019 reissues RFA-CA-24-017. Until awards appear under the new number, its funding history is the best guide to who wins under this program: 6 projects and $4.5M in FY2022–FY2026.

Projects funded

6

Distinct projects, FY2022–FY2026

New awards

6

Type 1 (new project) award records

NIH funding

$4.5M

Award dollars under RFA-CA-24-017, FY2022–FY2026

Funding by fiscal year

Award records, new awards, and funding by fiscal year under RFA-CA-24-017
Fiscal yearAward recordsNew awardsFunding
FY202200$0
FY202300$0
FY202400$0
FY202544$1.6M
FY202662$2.8M

Institutions with the most funding

  1. Baylor College of Medicine$1.2M · 1 project
  2. Cornell University$814K · 1 project

Funding institutes

  • NCI$4.5M · 10

Activity codes funded

FY2026 closed on September 30, 2026, but NIH keeps posting that year's awards to RePORTER for several weeks. FY2026 figures reflect records available on October 16, 2026 and may rise slightly at the next refresh.

Participating institutes

2 NIH institutes and offices take applications under RFA-CA-27-019. Contact the program officer at the institute that fits your research before applying.

  • NCI · National Cancer Institute
  • none

Related notices

NIH lists no related notices for RFA-CA-27-019 yet.

Award terms

Application types allowed
New Resubmission Revision The OER Glossary and the How to Apply Application Guide provide details on these application types. Only those application types listed here are allowed for this NOFO.
Award budget
Budgets are limited to 300,000 Direct Costs excluding consortium F&A) per year.
Project period
The maximum project period is three years. NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO.
Funds available and number of awards
NCI intends to commit 2,400,000 in FY 2027 to fund an estimate of 5 awards. Future year amounts will depend on annual appropriations.

Summarized from the NOFO text; the full NOFO governs eligibility, budget, and review.

Related NOFOs

Other open NOFOs for U01

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About this page

GotGrant gathers the NOFO, its participation and change notices, and its NOSIs from the NIH Guide for Grants and Contracts, and counts funded projects from NIH RePORTER by the opportunity number each award was made under. Data refreshed October 16, 2026; the NIH Guide is the authoritative source. See our data methodology.

Find who wins under this NOFO