NIH RFA · NCI · U24
RFA-CA-27-021: Sustained Support for Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional)
Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards
This Notice of Funding Opportunity (NOFO) solicits applications for the continued development and sustainment of high value informatics research resources to improve the acquisition, management, analysis, and dissemination of data and knowledge across the cancer research continuum including cancer biology, cancer treatment and diagnosis, early cancer detection, risk assessment and prevention, cancer control and epidemiology. As a component of the NCI's Informatics Technology for Cancer Research (ITCR) Program, this NOFO is focused on sustaining operations and maintaining and evolving the scientific relevance of existing, widely-adopted informatics tools and resources. This is in contrast to…
- NOFO number
- RFA-CA-27-021
- Type
- RFA
- Activity code
- U24
- Primary institute
- NCI · National Cancer Institute
- Clinical trials
- Optional
- Posted
- May 21, 2026
- Opens
- Jun 1, 2026
- Expires
- Oct 20, 2026
RFA-CA-27-021 due dates
1 application due date remains before the NOFO expires. Dates marked * are NIH standard due dates. Check the related notices below for changes NIH made after posting.
| New | Renewal / Resubmission / Revision (as allowed) | AIDS - New/Renewal/Resubmission/Revision, as allowed | Scientific Merit Review | Advisory Council Review | Earliest Start Date |
|---|---|---|---|---|---|
| July 01, 2026 | July 01, 2026 | Not Applicable | November 2026 | January 2027 | April 2027 |
| October 19, 2026 | October 19, 2026 | Not Applicable | March 2027 | May 2027 | July 2027 |
What its predecessor RFA-CA-24-019 funded
RFA-CA-27-021 reissues RFA-CA-24-019. Until awards appear under the new number, its funding history is the best guide to who wins under this program: 1 project and $2.0M in FY2022–FY2026.
Projects funded
1
Distinct projects, FY2022–FY2026
New awards
1
Type 1 (new project) award records
NIH funding
$2.0M
Award dollars under RFA-CA-24-019, FY2022–FY2026
Funding by fiscal year
| Fiscal year | Award records | New awards | Funding |
|---|---|---|---|
| FY2022 | 0 | 0 | $0 |
| FY2023 | 0 | 0 | $0 |
| FY2024 | 0 | 0 | $0 |
| FY2025 | 1 | 1 | $809K |
| FY2026 | 1 | 0 | $1.2M |
Institutions with the most funding
- Washington University$2.0M · 1 project
Funding institutes
- NCI$2.0M · 2
Activity codes funded
- U242 records
Most recent new awards
- Accelerating the expert-crowdsourcing of cancer variant interpretation in CIViC (opens NIH RePORTER)
Washington University · 1U24CA305456-01 · NCI · Notice Aug 29, 2025
$809KU24
FY2026 closed on September 30, 2026, but NIH keeps posting that year's awards to RePORTER for several weeks. FY2026 figures reflect records available on October 16, 2026 and may rise slightly at the next refresh.
Participating institutes
2 NIH institutes and offices take applications under RFA-CA-27-021. Contact the program officer at the institute that fits your research before applying.
- NCI · National Cancer Institute
- none
Related notices
NIH lists no related notices for RFA-CA-27-021 yet.
Award terms
- Application types allowed
- New Renewal Resubmission The OER Glossary and the How to Apply - Application Guide provide details on these application types. Only those application types listed here are allowed for this NOFO.
- Award budget
- Budgets are limited to 600,000 Direct Costs excluding consortium F&A) per year.
- Project period
- The maximum project period is five years. NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO.
- Funds available and number of awards
- NCI intends to commit 1,800,000 in FY 2027 to fund 2 awards.
Summarized from the NOFO text; the full NOFO governs eligibility, budget, and review.
Related NOFOs
- Reissue of RFA-CA-24-019.
- Companion NOFOs: RFA-CA-27-019, RFA-CA-27-020.
Other open NOFOs for U24
- RFA-CA-27-020Advanced Development of Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional)NCI · next due Oct 19, 2026
- PAR-28-057Pancreatic Cancer Detection Consortium: Management and Data Coordination Unit (U24 Clinical Trial Not Allowed)NCI · next due Jan 25, 2027
- RFA-CA-28-004Limited Competition: Biospecimen Banks to support NCI National Clinical Trials Network Biospecimen Banks (NCTN Biobanks) and the NCI Early-Phase and Experimental Clinical Trials Biospecimen Bank (EET Biobank) (U24 Clinical Trial Not Allowed)NCI · next due Feb 11, 2027
- RFA-AG-27-010Data Coordinating Center for the Aging and Alzheimer’s Disease Mouse Brain Atlas (AD-MBA) (U24 Clinical Trial Not Allowed)NIA · next due Nov 10, 2026
- RFA-HG-27-008IGVF Data and Coordinating Center (U24 Clinical trials Not Allowed)NHGRI · next due Dec 14, 2026
- PAR-27-013Data Coordinating Center for Multi-Site Investigator-Initiated Clinical Trials (Collaborative U24 Clinical Trial Required)NHLBI · next due Feb 1, 2027
About this page
GotGrant gathers the NOFO, its participation and change notices, and its NOSIs from the NIH Guide for Grants and Contracts, and counts funded projects from NIH RePORTER by the opportunity number each award was made under. Data refreshed October 16, 2026; the NIH Guide is the authoritative source. See our data methodology.