NIH RFA · NCI · U24
RFA-CA-28-004: Limited Competition: Biospecimen Banks to support NCI National Clinical Trials Network Biospecimen Banks (NCTN Biobanks) and the NCI Early-Phase and Experimental Clinical Trials Biospecimen Bank (EET Biobank) (U24 Clinical Trial Not Allowed)
Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards
This is a Notice of Funding Opportunity (NOFO) for a Limited Competition that will invite application(s) from eligible organization(s) to apply. Please see Section III. Eligibility for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered for funding. Through this limited competition Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) solicits applications to support continuation of two biospecimen banking resources. The National Clinical Trials Network (NCTN) Biospecimen Banks (NCTN Biobanks) support the NCI-funded NCTN and the Community Oncology…
- NOFO number
- RFA-CA-28-004
- Type
- RFA
- Activity code
- U24
- Primary institute
- NCI · National Cancer Institute
- Clinical trials
- Not Allowed
- Posted
- Oct 15, 2026
- Opens
- Jan 11, 2027
- Expires
- Feb 12, 2027
RFA-CA-28-004 due dates
1 application due date remains before the NOFO expires. Dates marked * are NIH standard due dates. Check the related notices below for changes NIH made after posting.
| New | Renewal / Resubmission / Revision (as allowed) | AIDS - New/Renewal/Resubmission/Revision, as allowed | Scientific Merit Review | Advisory Council Review | Earliest Start Date |
|---|---|---|---|---|---|
| Not Applicable | February 11, 2027 | Not Applicable | July 2027 | October 2027 | December 2027 |
What its predecessor RFA-CA-20-002 funded
RFA-CA-28-004 reissues RFA-CA-20-002. Until awards appear under the new number, its funding history is the best guide to who wins under this program: 5 projects and $80.7M in FY2022–FY2026.
Projects funded
5
Distinct projects, FY2022–FY2026
New awards
0
Type 1 (new project) award records
NIH funding
$80.7M
Award dollars under RFA-CA-20-002, FY2022–FY2026
Funding by fiscal year
| Fiscal year | Award records | New awards | Funding |
|---|---|---|---|
| FY2022 | 5 | 0 | $18.7M |
| FY2023 | 5 | 0 | $20.2M |
| FY2024 | 5 | 0 | $18.5M |
| FY2025 | 5 | 0 | $23.3M |
| FY2026 | 0 | 0 | $0 |
Institutions with the most funding
- Research Inst Nationwide Children's Hosp$34.4M · 2 projects
- Nrg Oncology Foundation, Inc.$18.1M · 1 project
- Ecog-Acrin Medical Research Foundation$16.5M · 1 project
- Washington University$11.7M · 1 project
Funding institutes
- NCI$80.7M · 20
Activity codes funded
- U2420 records
FY2026 closed on September 30, 2026, but NIH keeps posting that year's awards to RePORTER for several weeks. FY2026 figures reflect records available on October 16, 2026 and may rise slightly at the next refresh.
Participating institutes
2 NIH institutes and offices take applications under RFA-CA-28-004. Contact the program officer at the institute that fits your research before applying.
- NCI · National Cancer Institute
- none
Related notices
NIH lists no related notices for RFA-CA-28-004 yet.
Award terms
- Application types allowed
- Renewal The OER Glossary and the How to Apply - Application Guide provide details on these application types. Only those application types listed here are allowed for this NOFO.
- Award budget
- Application budgets must reflect the actual needs and scale of the proposed activities. Budget requests must not exceed 3.0 million in direct costs per year.However, the high budget level would be expected only for a large, comprehensive banking operation and significantly lower budget requests are expected for smaller banking operations.
- Project period
- Applications should request a project period of 6 years NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO.
- Funds available and number of awards
- To support the NCTN Biobanks and EET Biobank, NCI intends to fund an estimate of six awards, corresponding to a total of 19 million total costs) for fiscal year 2027.
Summarized from the NOFO text; the full NOFO governs eligibility, budget, and review.
Related NOFOs
- Reissue of RFA-CA-20-002.
Other open NOFOs for U24
- RFA-CA-27-020Advanced Development of Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional)NCI · next due Oct 19, 2026
- RFA-CA-27-021Sustained Support for Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional)NCI · next due Oct 19, 2026
- PAR-28-057Pancreatic Cancer Detection Consortium: Management and Data Coordination Unit (U24 Clinical Trial Not Allowed)NCI · next due Jan 25, 2027
- RFA-AG-27-010Data Coordinating Center for the Aging and Alzheimer’s Disease Mouse Brain Atlas (AD-MBA) (U24 Clinical Trial Not Allowed)NIA · next due Nov 10, 2026
- RFA-HG-27-008IGVF Data and Coordinating Center (U24 Clinical trials Not Allowed)NHGRI · next due Dec 14, 2026
- PAR-27-013Data Coordinating Center for Multi-Site Investigator-Initiated Clinical Trials (Collaborative U24 Clinical Trial Required)NHLBI · next due Feb 1, 2027
About this page
GotGrant gathers the NOFO, its participation and change notices, and its NOSIs from the NIH Guide for Grants and Contracts, and counts funded projects from NIH RePORTER by the opportunity number each award was made under. Data refreshed October 16, 2026; the NIH Guide is the authoritative source. See our data methodology.