NIH PAR · NCI · R21

PAR-25-096: Secondary Analysis and Integration of Existing Data to Elucidate Cancer Risk and Related Outcomes (R21 Clinical Trials Not Allowed)

Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards

Open for applicationsExpires Nov 17, 2026

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) along with other participating Institutes encourages submission of applications proposing to conduct secondary data analysis and integration of existing datasets and database resources, with the ultimate aim to elucidate cancer risk and related outcomes (e.g., risk prediction or reduction, survival, or response to treatment, etc.). The goal of this initiative is to address key scientific questions relevant to cancer by supporting the analysis of existing clinical, environmental, surveillance, health services, vital statistics, behavioral, lifestyle, genomic, and molecular profiles data. Applicants are…

Full NOFO in the NIH Guide Apply on Grants.gov

NOFO number
PAR-25-096
Type
PAR
Activity code
R21
Primary institute
NCI · National Cancer Institute
Clinical trials
Not Allowed
Posted
Nov 18, 2024
Opens
Jan 16, 2025
Expires
Nov 17, 2026

Projects funded under PAR-25-096

NIH RePORTER lists 9 projects funded under PAR-25-096 in FY2022–FY2026, with $3.5M in award dollars. Counts include each project's later non-competing years, which keep the original NOFO number.

Projects funded

9

Distinct projects, FY2022–FY2026

New awards

9

Type 1 (new project) award records

NIH funding

$3.5M

Award dollars under PAR-25-096, FY2022–FY2026

Funding by fiscal year

Award records, new awards, and funding by fiscal year under PAR-25-096
Fiscal yearAward recordsNew awardsFunding
FY202200$0
FY202300$0
FY202400$0
FY202500$0
FY202699$3.5M

Institutions with the most funding

  1. Kaiser Foundation Research Institute$440K · 1 project
  2. UT Southwestern Medical Center$427K · 1 project
  3. Georgetown University$412K · 1 project
  4. University of California Berkeley$412K · 1 project
  5. Johns Hopkins University$408K · 1 project
  6. University of Minnesota$400K · 1 project
  7. University of Texas at Austin$396K · 1 project
  8. Augusta University$396K · 1 project

Funding institutes

  • NCI$3.5M · 9

Activity codes funded

Most recent new awards

What its predecessor PAR-23-255 funded

PAR-25-096 reissues PAR-23-255. Its funding history is the best guide to who wins under this program: 10 projects and $3.7M in FY2022–FY2026.

Projects funded

10

Distinct projects, FY2022–FY2026

New awards

10

Type 1 (new project) award records

NIH funding

$3.7M

Award dollars under PAR-23-255, FY2022–FY2026

Funding by fiscal year

Award records, new awards, and funding by fiscal year under PAR-23-255
Fiscal yearAward recordsNew awardsFunding
FY202200$0
FY202300$0
FY202411$407K
FY202588$2.4M
FY202631$815K

Institutions with the most funding

  1. Yale University$431K · 1 project
  2. H. Lee Moffitt Cancer Ctr & Res Inst$423K · 1 project
  3. Cincinnati Childrens Hosp Med Ctr$413K · 1 project
  4. University of Maryland Baltimore$411K · 1 project
  5. University of Kentucky$409K · 1 project
  6. University of Tx MD Anderson Can Ctr$407K · 1 project
  7. Rutgers Biomedical and Health Sciences$404K · 1 project
  8. University of Minnesota$387K · 1 project

Funding institutes

  • NCI$3.7M · 12

Activity codes funded

Most recent new awards

FY2026 closed on September 30, 2026, but NIH keeps posting that year's awards to RePORTER for several weeks. FY2026 figures reflect records available on October 16, 2026 and may rise slightly at the next refresh.

Participating institutes

4 NIH institutes and offices take applications under PAR-25-096. Contact the program officer at the institute that fits your research before applying.

  • NCI · National Cancer Institute
  • NHGRI · National Human Genome Research Institute
  • NIA · National Institute on Aging
  • NIDCR · National Institute of Dental and Craniofacial Research

Related notices

  1. May 28, 2026

    Notice to Extend the

Notices of Special Interest (NOSIs)

NIH has attached 2 NOSIs to PAR-25-096; none are active now. A NOSI flags a topic an institute wants to fund through this NOFO.

Award terms

Application types allowed
NewResubmission The OER Glossary and the How to Apply Application Guide provide details on these application types. Only those application types listed here are allowed for this NOFO.
Award budget
Direct costs are limited to 275,000 over a two-year project period, with no more than 200,000 in direct costs allowed in any single year.
Project period
The maximum project period is 2 years. NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO.
Funds available and number of awards
The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications.

Summarized from the NOFO text; the full NOFO governs eligibility, budget, and review.

Related NOFOs

  • Reissue of PAR-23-255.
  • Companion NOFOs: PAR-25-095.

Other open NOFOs for R21

Browse all open NIH NOFOs

About this page

GotGrant gathers the NOFO, its participation and change notices, and its NOSIs from the NIH Guide for Grants and Contracts, and counts funded projects from NIH RePORTER by the opportunity number each award was made under. Data refreshed October 16, 2026; the NIH Guide is the authoritative source. See our data methodology.

Find who wins under this NOFO

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