NIH PAR · NCI · R01
PAR-25-095: Secondary Analysis and Integration of Existing Data to Elucidate Cancer Risk and Related Outcomes (R01 Clinical Trial Not Allowed)
Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards
Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) along with other participating Institutes encourages submission of applications proposing to conduct secondary data analysis and integration of existing datasets and database resources, with the ultimate aim to elucidate cancer risk and related outcomes (e.g., risk prediction or reduction, survival, or response to treatment, etc.). The goal of this initiative is to address key scientific questions relevant to cancer by supporting the analysis of existing clinical, environmental, surveillance, health services, vital statistics, behavioral, lifestyle, genomic, and molecular profiles data. Applicants are…
- NOFO number
- PAR-25-095
- Type
- PAR
- Activity code
- R01
- Primary institute
- NCI · National Cancer Institute
- Clinical trials
- Not Allowed
- Posted
- Nov 18, 2024
- Opens
- Jan 5, 2025
- Expires
- Nov 6, 2026
Projects funded under PAR-25-095
NIH RePORTER lists 11 projects funded under PAR-25-095 in FY2022–FY2026, with $5.2M in award dollars. Counts include each project's later non-competing years, which keep the original NOFO number.
Projects funded
11
Distinct projects, FY2022–FY2026
New awards
10
Type 1 (new project) award records
NIH funding
$5.2M
Award dollars under PAR-25-095, FY2022–FY2026
Funding by fiscal year
| Fiscal year | Award records | New awards | Funding |
|---|---|---|---|
| FY2022 | 0 | 0 | $0 |
| FY2023 | 0 | 0 | $0 |
| FY2024 | 0 | 0 | $0 |
| FY2025 | 0 | 0 | $0 |
| FY2026 | 11 | 10 | $5.2M |
Institutions with the most funding
- Institute for Systems Biology$556K · 1 project
- Sloan-Kettering Inst Can Research$547K · 1 project
- Duke University$517K · 1 project
- University of Kentucky$492K · 1 project
- Yale University$488K · 1 project
- Fred Hutchinson Cancer Center$488K · 1 project
- University of Southern California$479K · 1 project
- North Carolina State University Raleigh$466K · 1 project
Funding institutes
- NCI$4.2M · 9
- NIDCR$517K · 1
- NIA$466K · 1
Activity codes funded
- R0111 records
Most recent new awards
- Early Biomarkers for HPV-Driven Cancers: Modeling Risks and Screening (opens NIH RePORTER)
International Agency for Res on Cancer · 1R01CA307572-01 · NCI · Notice Sep 7, 2026
$322KR01
- Unveiling Cancer Risk Through AI-Powered Spatial Insights (opens NIH RePORTER)
Institute for Systems Biology · 1R01CA309386-01A1 · NCI · Notice Aug 24, 2026
$556KR01
- Cataloging disease processes over the lifespan of glioma (opens NIH RePORTER)
Yale University · 1R01CA315671-01 · NCI · Notice Aug 19, 2026
$488KR01
- Advancing Research to Develop Improved Methods for Understanding and Managing Multimorbidity in Multiple Myeloma (opens NIH RePORTER)
Washington University · 1R01CA309833-01 · NCI · Notice Aug 18, 2026
$347KR01
- AI-Enhanced Methods for Cancer Surveillance: Improving Automated Information Extraction with DAC for Clinically Actionable Cancer Types (opens NIH RePORTER)
University of Kentucky · 1R01CA316685-01 · NCI · Notice Aug 11, 2026
$492KR01
- Developing Evidence of the Risks and Benefits of PSA Screening in Black Men to Inform National Guidelines and Personalized Decision-Making (opens NIH RePORTER)
Veterans Medical Research Fdn/San Diego · 1R01CA315460-01 · NCI · Notice Jul 20, 2026
$460KR01
What its predecessor PAR-23-254 funded
PAR-25-095 reissues PAR-23-254. Its funding history is the best guide to who wins under this program: 7 projects and $7.6M in FY2022–FY2026.
Projects funded
7
Distinct projects, FY2022–FY2026
New awards
6
Type 1 (new project) award records
NIH funding
$7.6M
Award dollars under PAR-23-254, FY2022–FY2026
Funding by fiscal year
| Fiscal year | Award records | New awards | Funding |
|---|---|---|---|
| FY2022 | 0 | 0 | $0 |
| FY2023 | 0 | 0 | $0 |
| FY2024 | 1 | 0 | $427K |
| FY2025 | 7 | 6 | $4.5M |
| FY2026 | 4 | 0 | $2.6M |
Institutions with the most funding
- Graduate School of Public Health and Health Policy$2.1M · 1 project
- Duke University$1.9M · 1 project
- University of Florida$1.3M · 2 projects
- Mayo Clinic Rochester$954K · 1 project
- University of Chicago$910K · 1 project
- Temple Univ of the Commonwealth$439K · 1 project
Funding institutes
- NCI$5.9M · 8
- NIDCR$1.7M · 4
Activity codes funded
- R0110 records
- R562 records
Most recent new awards
- Integrating genome-wide association study data with single-cell `omics' to reveal the cellular effectors of glioblastoma predisposition (opens NIH RePORTER)
Duke University · 1R01CA295845-01A1 · NCI · Notice Sep 23, 2025
$1.9MR01
- Using germline and somatic genetics to elucidate glioma risk and improve patient outcomes (opens NIH RePORTER)
Mayo Clinic Rochester · 1R01CA298083-01A1 · NCI · Notice Aug 18, 2025
$485KR01
- The intersection of AI, clinical practice and health outcomes with linked Medical-Dental electronic records. (opens NIH RePORTER)
Temple Univ of the Commonwealth · 1R56DE035135-01 · NIDCR · Notice Aug 14, 2025
$439KR56
- Developing AI-Derived Multilevel Risk Scores for Oral Cavity and Oropharyngeal Cancer Patients (opens NIH RePORTER)
University of Florida · 1R56DE034781-01 · NIDCR · Notice Aug 11, 2025
$325KR56
- Characterizing cancer susceptibility mechanisms for TERT/CLPTM1L and other telomere-related regions (opens NIH RePORTER)
University of Chicago · 1R01CA297773-01A1 · NCI · Notice Jul 30, 2025
$464KR01
- Oral Cancer Diagnosis and Outcomes: Role of Medicaid Dental Coverage and Dental Utilization (opens NIH RePORTER)
University of Florida · 1R01DE035198-01 · NIDCR · Notice Jul 2, 2025
$486KR01
FY2026 closed on September 30, 2026, but NIH keeps posting that year's awards to RePORTER for several weeks. FY2026 figures reflect records available on October 16, 2026 and may rise slightly at the next refresh.
Participating institutes
4 NIH institutes and offices take applications under PAR-25-095. Contact the program officer at the institute that fits your research before applying.
- NCI · National Cancer Institute
- NHGRI · National Human Genome Research Institute
- NIA · National Institute on Aging
- NIDCR · National Institute of Dental and Craniofacial Research
Related notices
May 28, 2026
Notice to Extend the
Notices of Special Interest (NOSIs)
NIH has attached 2 NOSIs to PAR-25-095; none are active now. A NOSI flags a topic an institute wants to fund through this NOFO.
Award terms
- Application types allowed
- NewRenewalResubmissionRevision The OER Glossary and the How to Apply Application Guide provide details on these application types. Only those application types listed here are allowed for this NOFO.
- Award budget
- The budget is limited to 350,000 direct costs per year and should reflect the actual needs of the proposed project.
- Project period
- The maximum project period is 5 years. NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO.
- Funds available and number of awards
- The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications.
Summarized from the NOFO text; the full NOFO governs eligibility, budget, and review.
Related NOFOs
- Reissue of PAR-23-254.
- Companion NOFOs: PAR-25-096.
Other open NOFOs for R01
- PAR-25-336Toward Translation of Nanotechnology Cancer Interventions (TTNCI; R01 Clinical Trial Not Allowed)NCI · next due Nov 16, 2026
- PAR-27-072Bioengineering Research Grants (BRG) (R01 Clinical Trial Optional)NCI · next due Feb 5, 2027
- PAR-25-337Academic-Industrial Partnerships for Translation of Technologies for Diagnosis and Treatment (R01 - Clinical Trial Optional)NCI · next due Feb 5, 2027
- PAR-25-338Academic-Industrial Partnerships for Translation of Technologies for Diagnosis and Treatment (R01 - Clinical Trial Not Allowed)NCI · next due Feb 5, 2027
- PAR-25-243Basic Research in Cancer Health Disparities (R01 Clinical Trial Not Allowed)NCI · next due Feb 5, 2027
- PA-25-172Modular R01s in Cancer Control and Population Sciences (R01 Clinical Trial Optional)NCI · next due Feb 5, 2027
About this page
GotGrant gathers the NOFO, its participation and change notices, and its NOSIs from the NIH Guide for Grants and Contracts, and counts funded projects from NIH RePORTER by the opportunity number each award was made under. Data refreshed October 16, 2026; the NIH Guide is the authoritative source. See our data methodology.