NIH PAR · NCI · R01

PAR-27-072: Bioengineering Research Grants (BRG) (R01 Clinical Trial Optional)

Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards

Open for applicationsNext due date: Feb 5, 2027Expires Jul 6, 2029

This Notice of Funding Opportunity (NOFO) encourages collaborations between the life and physical sciences that: 1) apply a multidisciplinary bioengineering approach to the solution of a biomedical problem; and 2) integrate, optimize, validate, translate or otherwise accelerate the adoption of promising tools, methods, and techniques for a specific research or clinical problem in basic, translational, or clinical science and practice. An application may propose design-directed, developmental, discovery-driven, or hypothesis-driven research and is appropriate for small teams applying an integrative approach to increase our understanding of and solve problems in biological, clinical, or…

Full NOFO in the NIH Guide Apply on Grants.gov

NOFO number
PAR-27-072
Type
PAR
Activity code
R01
Primary institute
NCI · National Cancer Institute
Clinical trials
Optional
Posted
May 4, 2026
Opens
Sep 5, 2026
Expires
Jul 6, 2029

PAR-27-072 due dates

8 application due dates remain before the NOFO expires. Dates marked * are NIH standard due dates. Check the related notices below for changes NIH made after posting.

Application due dates and review cycles for PAR-27-072
NewRenewal / Resubmission / Revision (as allowed)AIDS - New/Renewal/Resubmission/Revision, as allowedScientific Merit ReviewAdvisory Council ReviewEarliest Start Date
October 05, 2026 *November 05, 2026 *Not ApplicableMarch 2027May 2027July 2027
February 05, 2027 *March 05, 2027 *Not ApplicableJuly 2027October 2027December 2027
June 05, 2027 *July 05, 2027 *Not ApplicableNovember 2027January 2028April 2028
October 05, 2027 *November 05, 2027 *Not ApplicableMarch 2028May 2028July 2028
February 05, 2028 *March 05, 2028 *Not ApplicableJuly 2028October 2028December 2028
June 05, 2028 *July 05, 2028 *Not ApplicableNovember 2028January 2029April 2029
October 05, 2028 *November 05, 2028 *Not ApplicableMarch 2029May 2029July 2029
February 05, 2029 *March 05, 2029 *Not ApplicableJuly 2029October 2029December 2029
June 05, 2029 *July 05, 2029 *Not ApplicableNovember 2029January 2030April 2030

What its predecessor PAR-22-243 funded

PAR-27-072 reissues PAR-22-243. Until awards appear under the new number, its funding history is the best guide to who wins under this program: 13 projects and $24.6M in FY2022–FY2026.

Projects funded

13

Distinct projects, FY2022–FY2026

New awards

11

Type 1 (new project) award records

NIH funding

$24.6M

Award dollars under PAR-22-243, FY2022–FY2026

Funding by fiscal year

Award records, new awards, and funding by fiscal year under PAR-22-243
Fiscal yearAward recordsNew awardsFunding
FY202200$0
FY202311$747K
FY202486$4.9M
FY2025134$10.4M
FY2026100$8.5M

Institutions with the most funding

  1. Brigham and Women's Hospital$6.2M · 2 projects
  2. University of Arizona$3.3M · 1 project
  3. University of Wisconsin-Madison$3.0M · 1 project
  4. University of Michigan at Ann Arbor$2.6M · 2 projects
  5. Northwestern University$2.1M · 1 project
  6. Johns Hopkins University$1.8M · 1 project
  7. University of Houston$1.4M · 1 project
  8. Case Western Reserve University$1.3M · 1 project

Funding institutes

  • NCI$16.9M · 20
  • NICHD$4.6M · 7
  • NINDS$3.1M · 5

Activity codes funded

Most recent new awards

FY2026 closed on September 30, 2026, but NIH keeps posting that year's awards to RePORTER for several weeks. FY2026 figures reflect records available on October 16, 2026 and may rise slightly at the next refresh.

Participating institutes

3 NIH institutes and offices take applications under PAR-27-072. Contact the program officer at the institute that fits your research before applying.

  • NCI · National Cancer Institute
  • NEI · National Eye Institute
  • NICHD · Eunice Kennedy Shriver National Institute of Child Health and Human Development

Related notices

NIH lists no related notices for PAR-27-072 yet.

Award terms

Application types allowed
New Renewal Resubmission Revision The OER Glossary and the How to Apply Application Guide provide details on these application types. Only those application types listed here are allowed for this NOFO.
Award budget
Application budgets are limited to less than 500,000 direct costs) per year.
Project period
The scope of the proposed project should determine the project period. The maximum award period is 5 years depending on the policy of each NIH Institute. Applicants are encouraged to review the current funding policy of each NIH Institute. NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO.
Funds available and number of awards
The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications.

Summarized from the NOFO text; the full NOFO governs eligibility, budget, and review.

Related NOFOs

  • Reissue of PAR-22-243.

Other open NOFOs for R01

Browse all open NIH NOFOs

About this page

GotGrant gathers the NOFO, its participation and change notices, and its NOSIs from the NIH Guide for Grants and Contracts, and counts funded projects from NIH RePORTER by the opportunity number each award was made under. Data refreshed October 16, 2026; the NIH Guide is the authoritative source. See our data methodology.

Find who wins under this NOFO

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