NIH RFA · NIMH · R34
RFA-MH-27-140: Optimizing Behavioral Sleep Interventions for Adolescents and Young Adults (R34 Clinical Trial Required)
Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards
NIMH seeks applications for pilot research to adapt, optimize, and test behavioral interventions that address common sleep problems in adolescents and young adults with or at risk for a mental health disorder. This notice of funding opportunity (NOFO) supports pilot clinical trials designed to evaluate the feasibility, tolerability, acceptability, safety, and potential effectiveness of the approach in real world settings. Applications should aim to conduct a preliminary test of the intervention's impact on sleep and mental health outcomes, as well as an examination of the mechanisms that underlie the intervention's effectiveness, and to obtain preliminary data needed as a prerequisite for…
- NOFO number
- RFA-MH-27-140
- Type
- RFA
- Activity code
- R34
- Primary institute
- NIMH · National Institute of Mental Health
- Clinical trials
- Required
- Posted
- May 28, 2026
- Opens
- Sep 22, 2026
- Expires
- Oct 23, 2026
RFA-MH-27-140 due dates
1 application due date remains before the NOFO expires. Dates marked * are NIH standard due dates. Check the related notices below for changes NIH made after posting.
| New | Renewal / Resubmission / Revision (as allowed) | AIDS - New/Renewal/Resubmission/Revision, as allowed | Scientific Merit Review | Advisory Council Review | Earliest Start Date |
|---|---|---|---|---|---|
| October 22, 2026 | October 22, 2026 | Not Applicable | March 2027 | May 2027 | July 2027 |
What its predecessor RFA-MH-25-130 funded
RFA-MH-27-140 reissues RFA-MH-25-130. Until awards appear under the new number, its funding history is the best guide to who wins under this program: 3 projects and $2.2M in FY2022–FY2026.
Projects funded
3
Distinct projects, FY2022–FY2026
New awards
3
Type 1 (new project) award records
NIH funding
$2.2M
Award dollars under RFA-MH-25-130, FY2022–FY2026
Funding by fiscal year
| Fiscal year | Award records | New awards | Funding |
|---|---|---|---|
| FY2022 | 0 | 0 | $0 |
| FY2023 | 0 | 0 | $0 |
| FY2024 | 0 | 0 | $0 |
| FY2025 | 0 | 0 | $0 |
| FY2026 | 3 | 3 | $2.2M |
Institutions with the most funding
- Rand Corporation$793K · 1 project
- University of Oregon$726K · 1 project
- Pennsylvania State Univ Hershey Med Ctr$705K · 1 project
Funding institutes
- NIMH$2.2M · 3
Activity codes funded
- R343 records
Most recent new awards
- Improving Sleep and Emotional Well-Being in Adolescents with Early Life Adversity: A Transdiagnostic Sleep and Circadian Intervention (opens NIH RePORTER)
Rand Corporation · 1R34MH141488-01 · NIMH · Notice Aug 19, 2026
$793KR34
- Transdiagnostic Sleep and Circadian Treatment for Autistic Adolescents (opens NIH RePORTER)
Pennsylvania State Univ Hershey Med Ctr · 1R34MH141224-01 · NIMH · Notice May 26, 2026
$705KR34
- Enhancing a Technology and Digital Media Use Intervention to Address Youth Sleep Problems (opens NIH RePORTER)
University of Oregon · 1R34MH141532-01 · NIMH · Notice Apr 24, 2026
$726KR34
FY2026 closed on September 30, 2026, but NIH keeps posting that year's awards to RePORTER for several weeks. FY2026 figures reflect records available on October 16, 2026 and may rise slightly at the next refresh.
Participating institutes
2 NIH institutes and offices take applications under RFA-MH-27-140. Contact the program officer at the institute that fits your research before applying.
- NIMH · National Institute of Mental Health
- none
Related notices
NIH lists no related notices for RFA-MH-27-140 yet.
Award terms
- Application types allowed
- New Resubmission The OER Glossary and the How to Apply Application Guide provide details on these application types. Only those application types listed here are allowed for this NOFO.
- Award budget
- Direct costs are limited to 450,000 over the entire project period, with no more than 225,000 in direct costs in any single year.
- Project period
- The scope of the proposed project should determine the project period. The maximum project period is 3 years. NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO.
- Funds available and number of awards
- NIMH intends to commit 1,500,000 total in FY 2027 to fund up to 6 awards.
Summarized from the NOFO text; the full NOFO governs eligibility, budget, and review.
Related NOFOs
- Reissue of RFA-MH-25-130.
Other open NOFOs for R34
- PAR-25-284Innovative Pilot Mental Health Services Research Not Involving Clinical Trials (R34 Clinical Trial Not Allowed)NIMH · next due Oct 16, 2026
- PAR-25-288Navigator Emergency Department Diversion Models for Non-Urgent Mental Health Concerns (R34 Clinical Trial Required)NIMH · next due Oct 16, 2026
- PAR-25-378Intervention Research to Improve Native American Health (R34 Clinical Trial Optional)NIDA · next due Oct 21, 2026
- PAR-25-358NEI Clinical Research Study Planning Grant Program (R34 Clinical Trial Not Allowed)NEI · next due Oct 16, 2026
- PAR-24-329Development and Testing of Novel Interventions to Improve HIV Prevention, Treatment, and Program Implementation for People Who Use Substances (R34 Clinical Trial Required)NIDA · next due Oct 16, 2026
- PAR-25-032NHLBI Clinical Trial Pilot Studies (R34 Clinical Trial Optional)NHLBI · next due Oct 16, 2026
About this page
GotGrant gathers the NOFO, its participation and change notices, and its NOSIs from the NIH Guide for Grants and Contracts, and counts funded projects from NIH RePORTER by the opportunity number each award was made under. Data refreshed October 16, 2026; the NIH Guide is the authoritative source. See our data methodology.