NIH RFA · NICHD · R21
RFA-HD-27-007: Using Archived Data and Specimen Collections to Advance Maternal and Pediatric HIV/AIDS Research (R21 CT Not Allowed)
Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards
The purpose of this Funding Opportunity is to address the needs of the maternal and pediatric HIV scientific community for research data translation and sharing.This initiative will support secondary data analyses using archived HIV/AIDS data and specimens. The goal of this initiative is to encourage the scientific community to utilize HIV/AIDS archived data sets and specimen collections to answer important questions about the epidemiology, pathogenesis, treatment, clinical manifestations, and HIV-associated co-infections and co-morbidities in maternal, pediatric and adolescent populations.
- NOFO number
- RFA-HD-27-007
- Type
- RFA
- Activity code
- R21
- Primary institute
- NICHD · Eunice Kennedy Shriver National Institute of Child Health and Human Development
- Clinical trials
- Not Allowed
- Posted
- May 19, 2026
- Opens
- Sep 21, 2026
- Expires
- Oct 21, 2028
RFA-HD-27-007 due dates
3 application due dates remain before the NOFO expires. Dates marked * are NIH standard due dates. Check the related notices below for changes NIH made after posting.
| New | Renewal / Resubmission / Revision (as allowed) | AIDS - New/Renewal/Resubmission/Revision, as allowed | Scientific Merit Review | Advisory Council Review | Earliest Start Date |
|---|---|---|---|---|---|
| October 21, 2026 | Not Applicable | Not Applicable | March 2027 | May 2027 | July 2027 |
| October 21, 2027 | Not Applicable | Not Applicable | March 2028 | May 2028 | July 2028 |
| October 20, 2028 | Not Applicable | Not Applicable | March 2029 | May 2029 | July 2029 |
What its predecessor RFA-HD-25-009 funded
RFA-HD-27-007 reissues RFA-HD-25-009. Until awards appear under the new number, its funding history is the best guide to who wins under this program: 5 projects and $2.4M in FY2022–FY2026.
Projects funded
5
Distinct projects, FY2022–FY2026
New awards
5
Type 1 (new project) award records
NIH funding
$2.4M
Award dollars under RFA-HD-25-009, FY2022–FY2026
Funding by fiscal year
| Fiscal year | Award records | New awards | Funding |
|---|---|---|---|
| FY2022 | 0 | 0 | $0 |
| FY2023 | 0 | 0 | $0 |
| FY2024 | 0 | 0 | $0 |
| FY2025 | 5 | 5 | $1.5M |
| FY2026 | 4 | 0 | $852K |
Institutions with the most funding
- Seattle Children's Hospital$538K · 1 project
- Weill Medical Coll of Cornell Univ$489K · 1 project
- Lurie Children's Hospital of Chicago$463K · 1 project
- University of Pennsylvania$458K · 1 project
- Johns Hopkins University$427K · 1 project
Funding institutes
- NICHD$1.9M · 8
- NIMH$458K · 1
Activity codes funded
- R219 records
Most recent new awards
- The effect of inherited maternal cells on BCG-specific T cell responses in HIV exposed and unexposed infants (opens NIH RePORTER)
Seattle Children's Hospital · 1R21HD118582-01 · NICHD · Notice Sep 5, 2025
$294KR21
- MAGIC-PHIV: Microbiome and Gut Inflammation in Cardiometabolic Health in Youth with Perinatally Acquired HIV (opens NIH RePORTER)
Lurie Children's Hospital of Chicago · 1R21HD118587-01 · NICHD · Notice Aug 25, 2025
$265KR21
- Identifying key engagement characteristics to enhance the effectiveness of digital HIV interventions for at-risk youth (opens NIH RePORTER)
University of Pennsylvania · 1R21MH141940-01 · NIMH · Notice Jul 24, 2025
$458KR21
- Virologic Determinants of Very Early Antiretroviral Treatment Responses of Infants with in utero HIV-1 (opens NIH RePORTER)
Johns Hopkins University · 1R21HD118590-01 · NICHD · Notice Apr 16, 2025
$233KR21
- Defining and modeling HIV-1-specific antibody function in HIV-1-exposed Infants passively Infused with broadly neutralizing antibodies in the IMPAACT P1112 trial. (opens NIH RePORTER)
Weill Medical Coll of Cornell Univ · 1R21HD118592-01 · NICHD · Notice Apr 9, 2025
$273KR21
FY2026 closed on September 30, 2026, but NIH keeps posting that year's awards to RePORTER for several weeks. FY2026 figures reflect records available on October 16, 2026 and may rise slightly at the next refresh.
Participating institutes
2 NIH institutes and offices take applications under RFA-HD-27-007. Contact the program officer at the institute that fits your research before applying.
- NICHD · Eunice Kennedy Shriver National Institute of Child Health and Human Development
- NIMH · National Institute of Mental Health
Related notices
NIH lists no related notices for RFA-HD-27-007 yet.
Award terms
- Application types allowed
- New The OER Glossary and the How to Apply Application Guide provide details on these application types. Only those application types listed here are allowed for this NOFO.
- Award budget
- Direct costs are limited to 275,000 over a two-year period, with no more than 200,000 in direct costs in any year.
- Project period
- The maximum project period is 2 years. NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO.
- Funds available and number of awards
- NICHD intends to commit 1,000,000 in FY 2027 to fund 2-3 awards.
Summarized from the NOFO text; the full NOFO governs eligibility, budget, and review.
Related NOFOs
- Reissue of RFA-HD-25-009.
Other open NOFOs for R21
- PAR-25-266Innovative Screening Approaches and Therapies for Screenable Disorders in Newborns (R21 - Clinical Trial Optional)NICHD · next due Oct 16, 2026
- PAR-25-113Advancement and Innovation in Measurement of Language Development and Predictors (R21 Clinical Trial Not Allowed)NICHD · next due Oct 16, 2026
- PA-25-304NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Not Allowed)NIH · next due Oct 16, 2026
- PA-25-306NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Required)NIH · next due Oct 16, 2026
- PAR-25-272New Approaches for Measuring Brain Changes Across Longer Timespans (R21 Clinical Trial Optional)NIA · next due Oct 16, 2026
- PAR-25-143Dissemination and Implementation Research in Health (R21 Clinical Trial Optional)NCI · next due Oct 16, 2026
About this page
GotGrant gathers the NOFO, its participation and change notices, and its NOSIs from the NIH Guide for Grants and Contracts, and counts funded projects from NIH RePORTER by the opportunity number each award was made under. Data refreshed October 16, 2026; the NIH Guide is the authoritative source. See our data methodology.