NIH PAR · NCI · R01

PAR-25-336: Toward Translation of Nanotechnology Cancer Interventions (TTNCI; R01 Clinical Trial Not Allowed)

Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards

Open for applicationsNext due date: Nov 16, 2026Expires Nov 16, 2027

Through this Notice of Funding Opportunity (NOFO), entitled "Toward Translation of Nanotechnology Cancer Interventions" (TTNCI), the National Cancer Institute (NCI) encourages applications for advanced pre-clinical research, supporting translation of nanotechnology-based cancer diagnostics and therapeutics. TTNCI awards are designed to mature experimental nanomedicines relying on nanoparticles and nano-devices which demonstrate strong potential to improve cancer treatment effectiveness due to the combination of nanoparticle/nano-device structural design and/or therapeutic/diagnostic cargo which is delivered. TTNCI awards are expected to enable further development of proposed…

Full NOFO in the NIH Guide Apply on Grants.gov

NOFO number
PAR-25-336
Type
PAR
Activity code
R01
Primary institute
NCI · National Cancer Institute
Clinical trials
Not Allowed
Posted
Dec 16, 2024
Opens
Apr 19, 2025
Expires
Nov 16, 2027

PAR-25-336 due dates

3 application due dates remain before the NOFO expires. Dates marked * are NIH standard due dates. Check the related notices below for changes NIH made after posting.

Application due dates and review cycles for PAR-25-336
Application Due Date(s)Renewal / Resubmission / Revision (as allowed)AIDS - New/Renewal/Resubmission/Revision, as allowedScientific Merit ReviewAdvisory Council ReviewEarliest Start Date
May 19, 2025May 19, 2025Not ApplicableNovember 2025January 2026April 2026
November 17, 2025November 17, 2025Not ApplicableMarch 2026May 2026July 2026
May 18, 2026May 18, 2026Not ApplicableNovember 2026January 2027April 2027
November 16, 2026November 16, 2026Not ApplicableMarch 2027May 2027July 2027
May 17, 2027May 17, 2027Not ApplicableNovember 2027January 2028April 2028
November 15, 2027November 15, 2027Not ApplicableMarch 2028May 2028July 2028

Projects funded under PAR-25-336

NIH RePORTER lists 3 projects funded under PAR-25-336 in FY2022–FY2026, with $2.0M in award dollars. Counts include each project's later non-competing years, which keep the original NOFO number.

Projects funded

3

Distinct projects, FY2022–FY2026

New awards

3

Type 1 (new project) award records

NIH funding

$2.0M

Award dollars under PAR-25-336, FY2022–FY2026

Funding by fiscal year

Award records, new awards, and funding by fiscal year under PAR-25-336
Fiscal yearAward recordsNew awardsFunding
FY202200$0
FY202300$0
FY202400$0
FY202500$0
FY202633$2.0M

Institutions with the most funding

  1. Sloan-Kettering Inst Can Research$709K · 1 project
  2. University of Houston$657K · 1 project
  3. Massachusetts General Hospital$651K · 1 project

Funding institutes

  • NCI$2.0M · 3

Activity codes funded

Most recent new awards

What its predecessor PAR-22-071 funded

PAR-25-336 reissues PAR-22-071. Its funding history is the best guide to who wins under this program: 10 projects and $20.7M in FY2022–FY2026.

Projects funded

10

Distinct projects, FY2022–FY2026

New awards

10

Type 1 (new project) award records

NIH funding

$20.7M

Award dollars under PAR-22-071, FY2022–FY2026

Funding by fiscal year

Award records, new awards, and funding by fiscal year under PAR-22-071
Fiscal yearAward recordsNew awardsFunding
FY202200$0
FY202366$3.6M
FY202482$4.6M
FY2025102$8.1M
FY202670$4.3M

Institutions with the most funding

  1. Vanderbilt University Medical Center$2.6M · 1 project
  2. University of California, San Francisco$2.5M · 1 project
  3. University of Washington$2.4M · 1 project
  4. University of Tx MD Anderson Can Ctr$2.2M · 1 project
  5. Cedars-Sinai Medical Center$2.2M · 1 project
  6. University of California Los Angeles$2.1M · 1 project
  7. University of Pennsylvania$1.9M · 1 project
  8. University of California at Davis$1.9M · 1 project

Funding institutes

  • NCI$20.7M · 31

Activity codes funded

Most recent new awards

FY2026 closed on September 30, 2026, but NIH keeps posting that year's awards to RePORTER for several weeks. FY2026 figures reflect records available on October 16, 2026 and may rise slightly at the next refresh.

Participating institutes

2 NIH institutes and offices take applications under PAR-25-336. Contact the program officer at the institute that fits your research before applying.

  • NCI · National Cancer Institute
  • none

Related notices

  1. Mar 31, 2025 · NOT-OD-24-084

    This funding opportunity was updated to align with agency priorities. Carefully reread the full funding opportunity and make any needed adjustments to your application prior to submission.April 4, 2024 - Overview of Grant Application and Review Changes for Due Dates on or after January 25,…

  2. Aug 31, 2022 · NOT-OD-22-198

    Implementation Changes for Genomic Data Sharing Plans Included with Applications Due on or after January 25, 2023. See Notice NOT-OD-22-198.

  3. Aug 5, 2022 · NOT-OD-22-189

    Implementation Details for the NIH Data Management and Sharing Policy. See Notice NOT-OD-22-189.

Award terms

Application types allowed
NewResubmission The OER Glossary and the How to Apply Application Guide provide details on these application types. Only those application types listed here are allowed for this NOFO.
Award budget
Application budgets are limited to 475,000 in direct costs per year and need to reflect the actual needs of the proposed project.
Project period
The maximum project period is 4 years. NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO.
Funds available and number of awards
The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications.

Summarized from the NOFO text; the full NOFO governs eligibility, budget, and review.

Related NOFOs

  • Reissue of PAR-22-071.

Other open NOFOs for R01

Browse all open NIH NOFOs

About this page

GotGrant gathers the NOFO, its participation and change notices, and its NOSIs from the NIH Guide for Grants and Contracts, and counts funded projects from NIH RePORTER by the opportunity number each award was made under. Data refreshed October 16, 2026; the NIH Guide is the authoritative source. See our data methodology.

Find who wins under this NOFO

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