NIH PAR · NCI · R01

PAR-25-167: Cancer Prevention and Control Clinical Trials Grant Program (R01 Clinical Trial Required)

Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards

Open for applicationsExpires Jan 8, 2027

Through this notice of funding opportunity (NOFO), the National Cancer Institute (NCI) invites applications for support of investigator-initiated clinical trials that have the potential to reduce the burden of cancer through improvements in early detection, screening, prevention and interception, healthcare delivery, quality of life, and/or survivorship related to cancer; with such attributes, the proposed studies should also have the potential to improve clinical practice and/or public health. Applications submitted to this NOFO must include studies that meet the National Institutes of Health (NIH) definition of a clinical trial (see NOT-OD-15-015 for details) and provide specific clinical…

Full NOFO in the NIH Guide Apply on Grants.gov

NOFO number
PAR-25-167
Type
PAR
Activity code
R01
Primary institute
NCI · National Cancer Institute
Clinical trials
Required
Posted
Nov 12, 2024
Opens
Jan 5, 2025
Expires
Jan 8, 2027

PAR-25-167 due dates

No application due dates remain in the listed cycles. Dates marked * are NIH standard due dates. Check the related notices below for changes NIH made after posting.

Application due dates and review cycles for PAR-25-167
Application Due Date(s)Renewal / Resubmission / Revision (as allowed)AIDS - New/Renewal/Resubmission/Revision, as allowedScientific Merit ReviewAdvisory Council ReviewEarliest Start Date
February 05, 2025March 05, 2025 *May 07, 2025 *July 2025October 2025December 2025
June 05, 2025July 05, 2025 *September 07, 2025 *November 2025January 2026April 2026
October 05, 2025November 05, 2025 *January 07, 2026 *March 2026May 2026July 2026
February 05, 2026March 05, 2026 *May 07, 2026 *July 2026October 2026December 2026
June 05, 2026July 05, 2026 *Not ApplicableNovember 2026January 2027April 2027
October 05, 2026November 05, 2026 *Not ApplicableMarch 2027May 2027July 2027

Projects funded under PAR-25-167

NIH RePORTER lists 71 projects funded under PAR-25-167 in FY2022–FY2026, with $48.3M in award dollars. Counts include each project's later non-competing years, which keep the original NOFO number.

Projects funded

71

Distinct projects, FY2022–FY2026

New awards

71

Type 1 (new project) award records

NIH funding

$48.3M

Award dollars under PAR-25-167, FY2022–FY2026

Funding by fiscal year

Award records, new awards, and funding by fiscal year under PAR-25-167
Fiscal yearAward recordsNew awardsFunding
FY202200$0
FY202300$0
FY202400$0
FY202500$0
FY20267171$48.3M

Institutions with the most funding

  1. Sloan-Kettering Inst Can Research$4.5M · 6 projects
  2. University of Tx MD Anderson Can Ctr$3.1M · 5 projects
  3. University of Rochester$2.2M · 1 project
  4. Massachusetts General Hospital$2.0M · 3 projects
  5. Rutgers Biomedical and Health Sciences$2.0M · 3 projects
  6. University of Michigan at Ann Arbor$1.9M · 3 projects
  7. Fred Hutchinson Cancer Center$1.7M · 2 projects
  8. University of Oklahoma Hlth Sciences Ctr$1.6M · 3 projects

Funding institutes

  • NCI$48.3M · 71

Activity codes funded

Most recent new awards

What its predecessor PAR-24-072 funded

PAR-25-167 reissues PAR-24-072. Its funding history is the best guide to who wins under this program: 37 projects and $52.9M in FY2022–FY2026.

Projects funded

37

Distinct projects, FY2022–FY2026

New awards

36

Type 1 (new project) award records

NIH funding

$52.9M

Award dollars under PAR-24-072, FY2022–FY2026

Funding by fiscal year

Award records, new awards, and funding by fiscal year under PAR-24-072
Fiscal yearAward recordsNew awardsFunding
FY202200$0
FY202300$0
FY202400$0
FY20253734$29.5M
FY2026372$23.4M

Institutions with the most funding

  1. Massachusetts General Hospital$5.2M · 4 projects
  2. University of Miami Coral Gables$3.9M · 2 projects
  3. University of Virginia$3.4M · 1 project
  4. Case Western Reserve University$3.2M · 1 project
  5. Yale University$2.7M · 2 projects
  6. Univ of North Carolina Chapel Hill$2.5M · 2 projects
  7. Beth Israel Deaconess Medical Center$1.5M · 1 project
  8. Fred Hutchinson Cancer Center$1.5M · 1 project

Funding institutes

  • NCI$52.9M · 74

Activity codes funded

Most recent new awards

FY2026 closed on September 30, 2026, but NIH keeps posting that year's awards to RePORTER for several weeks. FY2026 figures reflect records available on October 16, 2026 and may rise slightly at the next refresh.

Participating institutes

2 NIH institutes and offices take applications under PAR-25-167. Contact the program officer at the institute that fits your research before applying.

  • NCI · National Cancer Institute
  • none

Related notices

  1. Mar 31, 2025 · NOT-OD-24-084

    This funding opportunity was updated to align with agency priorities. Carefully reread the full funding opportunity and make any needed adjustments to your application prior to submission.April 4, 2024 - Overview of Grant Application and Review Changes for Due Dates on or after January 25,…

  2. Aug 31, 2022 · NOT-OD-22-198

    Implementation Changes for Genomic Data Sharing Plans Included with Applications Due on or after January 25, 2023. See Notice NOT-OD-22-198.

  3. Aug 5, 2022 · NOT-OD-22-189

    Implementation Details for the NIH Data Management and Sharing Policy.

Notices of Special Interest (NOSIs)

NIH has attached 23 NOSIs to PAR-25-167; none are active now. A NOSI flags a topic an institute wants to fund through this NOFO.

Award terms

Application types allowed
NewRenewalResubmissionRevision The OER Glossary and the How to Apply Application Guide provide details on these application types. Only those application types listed here are allowed for this NOFO.
Award budget
Application budgets are not limited but need to reflect the actual needs of the proposed project.
Project period
 The maximum project period is 5 years. NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO.
Funds available and number of awards
The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications.

Summarized from the NOFO text; the full NOFO governs eligibility, budget, and review.

Related NOFOs

  • Reissue of PAR-24-072.
  • Companion NOFOs: PAR-25-081.

Other open NOFOs for R01

Browse all open NIH NOFOs

About this page

GotGrant gathers the NOFO, its participation and change notices, and its NOSIs from the NIH Guide for Grants and Contracts, and counts funded projects from NIH RePORTER by the opportunity number each award was made under. Data refreshed October 16, 2026; the NIH Guide is the authoritative source. See our data methodology.

Find who wins under this NOFO

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