NIH PAR · NIDA · R34

PAR-24-329: Development and Testing of Novel Interventions to Improve HIV Prevention, Treatment, and Program Implementation for People Who Use Substances (R34 Clinical Trial Required)

Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards

Open for applicationsNext due date: Oct 16, 2026Expires Mar 17, 2027

This notice of funding opportunity (NOFO) encourages formative research, intervention development, and pilot-testing of interventions. Primary scientific areas of focus include the feasibility, tolerability, acceptability and safety of novel or adapted interventions that target HIV prevention, treatment or services research for people who use drugs. For the purposes of this NOFO, "intervention" may include behavioral, social, or structural approaches, as well as combination biomedical and behavioral approaches that prevent the acquisition and transmission of HIV infection, or improve clinical outcomes for persons living with HIV.

Full NOFO in the NIH Guide Apply on Grants.gov

NOFO number
PAR-24-329
Type
PAR
Activity code
R34
Primary institute
NIDA · National Institute on Drug Abuse
Clinical trials
Required
Posted
Jan 8, 2025
Opens
Apr 7, 2025
Expires
Mar 17, 2027

PAR-24-329 due dates

2 application due dates remain before the NOFO expires. Dates marked * are NIH standard due dates. Check the related notices below for changes NIH made after posting.

Application due dates and review cycles for PAR-24-329
NewRenewal / Resubmission / Revision (as allowed)AIDS - New/Renewal/Resubmission/Revision, as allowedScientific Merit ReviewAdvisory Council ReviewEarliest Start Date
Not ApplicableNot ApplicableMay 07, 2025 *July 2025October 2025December 2025
Not ApplicableNot ApplicableSeptember 07, 2025November 2025January 2026April 2026
Not ApplicableNot ApplicableJanuary 07, 2026 *March 2026May 2026July 2026
Not ApplicableNot ApplicableMay 07, 2026 *July 2026October 2026December 2026
June 16, 2026 *July 16, 2026*Not ApplicableNovember 2026January 2027April 2027
October 16, 2026 *November 16, 2026Not ApplicableMarch 2027May 2027July 2027
February 16, 2027March 16, 2027 *Not ApplicableJuly 2027October 2027December 2027

Projects funded under PAR-24-329

NIH RePORTER lists 6 projects funded under PAR-24-329 in FY2022–FY2026, with $2.3M in award dollars. Counts include each project's later non-competing years, which keep the original NOFO number.

Projects funded

6

Distinct projects, FY2022–FY2026

New awards

6

Type 1 (new project) award records

NIH funding

$2.3M

Award dollars under PAR-24-329, FY2022–FY2026

Funding by fiscal year

Award records, new awards, and funding by fiscal year under PAR-24-329
Fiscal yearAward recordsNew awardsFunding
FY202200$0
FY202300$0
FY202400$0
FY202500$0
FY202666$2.3M

Institutions with the most funding

  1. Albert Einstein College of Medicine$756K · 1 project
  2. Duke University$727K · 1 project
  3. Florida State University$234K · 1 project
  4. University of Washington$206K · 1 project
  5. Emory University$176K · 1 project
  6. Johns Hopkins University$156K · 1 project

Funding institutes

  • NIDA$2.3M · 6

Activity codes funded

  • R346 records

Most recent new awards

What its predecessor PA-21-205 funded

PAR-24-329 reissues PA-21-205. Its funding history is the best guide to who wins under this program: 16 projects and $10.2M in FY2022–FY2026.

Projects funded

16

Distinct projects, FY2022–FY2026

New awards

16

Type 1 (new project) award records

NIH funding

$10.2M

Award dollars under PA-21-205, FY2022–FY2026

Funding by fiscal year

Award records, new awards, and funding by fiscal year under PA-21-205
Fiscal yearAward recordsNew awardsFunding
FY202244$895K
FY202395$2.2M
FY2024123$2.8M
FY2025153$3.0M
FY202671$1.4M

Institutions with the most funding

  1. Columbia Univ New York Morningside$753K · 1 project
  2. University of Texas Hlth Science Center$735K · 1 project
  3. Friends Research Institute, Inc.$724K · 1 project
  4. Miriam Hospital$717K · 1 project
  5. University of California, San Diego$710K · 1 project
  6. Temple Univ of the Commonwealth$698K · 1 project
  7. Ohio University Athens$698K · 1 project
  8. University of Miami School of Medicine$690K · 1 project

Funding institutes

  • NIDA$10.2M · 47

Activity codes funded

  • R3447 records

Most recent new awards

FY2026 closed on September 30, 2026, but NIH keeps posting that year's awards to RePORTER for several weeks. FY2026 figures reflect records available on October 16, 2026 and may rise slightly at the next refresh.

Participating institutes

2 NIH institutes and offices take applications under PAR-24-329. Contact the program officer at the institute that fits your research before applying.

  • NIDA · National Institute on Drug Abuse
  • none

Related notices

  1. Jan 28, 2026 · NOT-OD-26-029

    NIH Removing AIDS Application Due Dates from NOFOs.

  2. Mar 31, 2025 · NOT-OD-24-084

    This funding opportunity was updated to align with agency priorities. Carefully reread the full funding opportunity and make any needed adjustments to your application prior to submission.April 4, 2024 - Overview of Grant Application and Review Changes for Due Dates on or after January 25,…

  3. Aug 31, 2022 · NOT-OD-22-198

    Implementation Changes for Genomic Data Sharing Plans Included with Applications Due on or after January 25, 2023. See Notice NOT-OD-22-198.

  4. Aug 5, 2022 · NOT-OD-22-189

    Implementation Details for the NIH Data Management and Sharing Policy.

Notices of Special Interest (NOSIs)

NIH has attached 1 NOSI to PAR-24-329; none are active now. A NOSI flags a topic an institute wants to fund through this NOFO.

Award terms

Application types allowed
NewResubmission The OER Glossary and the How to Apply Application Guide provide details on these application types. Only those application types listed here are allowed for this NOFO.
Award budget
Applicants may request direct costs of up to 450,000 for three years. Although variations from year to year are permissible, in no case may any year be more than 225,000 in direct costs, and total direct costs for the entire project period may not exceed 450,000.
Project period
The maximum period is 3 years. NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO.
Funds available and number of awards
The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications.

Summarized from the NOFO text; the full NOFO governs eligibility, budget, and review.

Related NOFOs

  • Reissue of PA-21-205.

Other open NOFOs for R34

Browse all open NIH NOFOs

About this page

GotGrant gathers the NOFO, its participation and change notices, and its NOSIs from the NIH Guide for Grants and Contracts, and counts funded projects from NIH RePORTER by the opportunity number each award was made under. Data refreshed October 16, 2026; the NIH Guide is the authoritative source. See our data methodology.

Find who wins under this NOFO

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