NIH PA · NIAMS · R34
PA-25-093: Limited Competition: CCRP Initiative: Promoting a Basic Understanding of Chemical Threats to Skin (R34 Clinical Trial Not Allowed)
Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards
This Notice of Funding Opportunity (NOFO) intends to support fundamental research that will contribute to basic understanding of skin injuries caused by chemicals that have been identified as public health threats, with an emphasis on investigating the commonalities of such injuries and identifying potential shared signaling pathways and therapeutic targets for medical countermeasure development.
- NOFO number
- PA-25-093
- Type
- PA
- Activity code
- R34
- Primary institute
- NIAMS · National Institute of Arthritis and Musculoskeletal and Skin Diseases
- Clinical trials
- Not Allowed
- Posted
- Oct 4, 2024
- Opens
- Jan 16, 2025
- Expires
- Jan 8, 2028
PA-25-093 due dates
4 application due dates remain before the NOFO expires. Dates marked * are NIH standard due dates. Check the related notices below for changes NIH made after posting.
| Application Due Date(s) | Renewal / Resubmission / Revision (as allowed) | AIDS - New/Renewal/Resubmission/Revision, as allowed | Scientific Merit Review | Advisory Council Review | Earliest Start Date |
|---|---|---|---|---|---|
| February 16, 2025 | March 16, 2025 * | Not Applicable | July 2025 | October 2025 | December 2025 |
| June 16, 2025 | July 16, 2025 * | Not Applicable | November 2025 | January 2026 | April 2026 |
| October 16, 2025 | November 16, 2025 * | Not Applicable | March 2026 | May 2026 | July 2026 |
| February 16, 2026 | March 16, 2026 * | Not Applicable | July 2026 | October 2026 | December 2026 |
| June 16, 2026 | July 16, 2026 * | Not Applicable | November 2026 | January 2027 | April 2027 |
| October 16, 2026 | November 16, 2026 * | Not Applicable | March 2027 | May 2027 | July 2027 |
| February 16, 2027 | March 16, 2027 * | Not Applicable | July 2027 | October 2027 | December 2027 |
| June 16, 2027 | July 16, 2027 * | Not Applicable | November 2027 | January 2028 | April 2028 |
| October 16, 2027 | November 16, 2027 * | Not Applicable | March 2028 | May 2028 | July 2028 |
Projects funded under PA-25-093
NIH RePORTER lists 2 projects funded under PA-25-093 in FY2022–FY2026, with $483K in award dollars. Counts include each project's later non-competing years, which keep the original NOFO number.
Projects funded
2
Distinct projects, FY2022–FY2026
New awards
2
Type 1 (new project) award records
NIH funding
$483K
Award dollars under PA-25-093, FY2022–FY2026
Funding by fiscal year
| Fiscal year | Award records | New awards | Funding |
|---|---|---|---|
| FY2022 | 0 | 0 | $0 |
| FY2023 | 0 | 0 | $0 |
| FY2024 | 0 | 0 | $0 |
| FY2025 | 0 | 0 | $0 |
| FY2026 | 2 | 2 | $483K |
Institutions with the most funding
- Johns Hopkins University$247K · 1 project
- University of Pittsburgh at Pittsburgh$236K · 1 project
Funding institutes
- NIAMS$483K · 2
Activity codes funded
- R342 records
Most recent new awards
- Understanding mechanisms of cell-cell exchange of topically exposed chemicals of concern provoking human skin injury, hypodermal damage, and wound disrepair (opens NIH RePORTER)
University of Pittsburgh at Pittsburgh · 1R34AR087022-01A1 · NIAMS · Notice Aug 18, 2026
$236KR34
- Glutamine metabolism and vesicant pathogenesis (opens NIH RePORTER)
Johns Hopkins University · 1R34AR087629-01 · NIAMS · Notice Aug 18, 2026
$247KR34
What its predecessor PAS-21-245 funded
PA-25-093 reissues PAS-21-245. Its funding history is the best guide to who wins under this program: 6 projects and $4.3M in FY2022–FY2026.
Projects funded
6
Distinct projects, FY2022–FY2026
New awards
6
Type 1 (new project) award records
NIH funding
$4.3M
Award dollars under PAS-21-245, FY2022–FY2026
Funding by fiscal year
| Fiscal year | Award records | New awards | Funding |
|---|---|---|---|
| FY2022 | 1 | 1 | $236K |
| FY2023 | 3 | 2 | $660K |
| FY2024 | 7 | 2 | $1.6M |
| FY2025 | 5 | 1 | $1.1M |
| FY2026 | 3 | 0 | $663K |
Institutions with the most funding
- University of Pittsburgh at Pittsburgh$867K · 1 project
- University of California-Irvine$865K · 1 project
- University of Illinois at Chicago$711K · 1 project
- University of Texas Med Br Galveston$683K · 1 project
- Wright State University$675K · 1 project
- University of Chicago$504K · 1 project
Funding institutes
- NIAMS$4.3M · 19
Activity codes funded
- R3419 records
Most recent new awards
- Coordinated cytoskeletal and cell adhesion dynamics in vesicant induced skin injury (opens NIH RePORTER)
University of Chicago · 1R34AR084090-01A1 · NIAMS · Notice Dec 16, 2024
$260KR34
- Integrated spatial omics to elucidate conserved inflammatory mechanisms of vesicant-induced skin injury (opens NIH RePORTER)
University of Texas Med Br Galveston · 1R34AR084669-01 · NIAMS · Notice Sep 17, 2024
$317KR34
- Explant human skin perfusion model to study mechanisms of chemical injury and mitigation (opens NIH RePORTER)
University of Pittsburgh at Pittsburgh · 1R34AR083572-01 · NIAMS · Notice Dec 8, 2023
$236KR34
- Oxidized lipids and microvesicle particles as effectors for chemical threats to skin (opens NIH RePORTER)
Wright State University · 1R34AR082554-01 · NIAMS · Notice Jul 10, 2023
$188KR34
- The Role of Macrophages in Vesicant Skin Injury and Repair (opens NIH RePORTER)
University of Illinois at Chicago · 1R34AR081456-01A1 · NIAMS · Notice Jun 12, 2023
$237KR34
- The Initiation of Vesicant Skin Injury at a Single Cell Level (opens NIH RePORTER)
University of California-Irvine · 1R34AR081502-01 · NIAMS · Notice Sep 21, 2022
$236KR34
FY2026 closed on September 30, 2026, but NIH keeps posting that year's awards to RePORTER for several weeks. FY2026 figures reflect records available on October 16, 2026 and may rise slightly at the next refresh.
Participating institutes
2 NIH institutes and offices take applications under PA-25-093. Contact the program officer at the institute that fits your research before applying.
- NIAMS · National Institute of Arthritis and Musculoskeletal and Skin Diseases
- NIAID · National Institute of Allergy and Infectious Diseases
Related notices
Mar 31, 2025 · NOT-OD-24-084
This funding opportunity was updated to align with agency priorities. Carefully reread the full funding opportunity and make any needed adjustments to your application prior to submission.April 4, 2024 - Overview of Grant Application and Review Changes for Due Dates on or after January 25,…
Aug 31, 2022 · NOT-OD-22-198
Implementation Changes for Genomic Data Sharing Plans Included with Applications Due on or after January 25, 2023. See Notice NOT-OD-22-198.
Aug 5, 2022 · NOT-OD-22-189
Implementation Details for the NIH Data Management and Sharing Policy. See Notice NOT-OD-22-189.
Award terms
- Application types allowed
- NewResubmissionRevision The OER Glossary and the How to Apply Application Guide provide details on these application types. Only those application types listed here are allowed for this NOFO.
- Award budget
- The Direct Cost is limited to 225,000 in any given year and 450,000 over the 3-year project period.A Modular budget is required.
- Project period
- Project period is limited to 3 years. NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO.
- Funds available and number of awards
- NIAMS and NIAID intend to fund an estimate of up to 5 awards, corresponding to a total of 1.25M, for fiscal year 2025. Future year amounts will depend on annual appropriations.
Summarized from the NOFO text; the full NOFO governs eligibility, budget, and review.
Related NOFOs
- Reissue of PAS-21-245.
Other open NOFOs for R34
- PAR-25-358NEI Clinical Research Study Planning Grant Program (R34 Clinical Trial Not Allowed)NEI · next due Oct 16, 2026
- PAR-24-329Development and Testing of Novel Interventions to Improve HIV Prevention, Treatment, and Program Implementation for People Who Use Substances (R34 Clinical Trial Required)NIDA · next due Oct 16, 2026
- PAR-25-284Innovative Pilot Mental Health Services Research Not Involving Clinical Trials (R34 Clinical Trial Not Allowed)NIMH · next due Oct 16, 2026
- PAR-25-032NHLBI Clinical Trial Pilot Studies (R34 Clinical Trial Optional)NHLBI · next due Oct 16, 2026
- PAR-25-100Pilot Health Services and Economic Research on the Treatment of Drug, Alcohol, and Tobacco Use Disorders (R34 Clinical Trial Optional)NIDA · next due Oct 16, 2026
- PAR-25-159Prevention and Intervention Approaches for Fetal Alcohol Spectrum Disorders (R34 Clinical Trial Optional)NIAAA · next due Oct 16, 2026
About this page
GotGrant gathers the NOFO, its participation and change notices, and its NOSIs from the NIH Guide for Grants and Contracts, and counts funded projects from NIH RePORTER by the opportunity number each award was made under. Data refreshed October 16, 2026; the NIH Guide is the authoritative source. See our data methodology.