NIH RFA · NINDS · R18

RFA-NS-24-031: BRAIN Initiative: Preclinical Proof of Concept for Novel Recording and Modulation Technologies in the Human CNS (R18 - Clinical Trial Not Allowed)

Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards

Open for applicationsExpires Jan 29, 2027

Awarded activities will facilitate the translation of novel recording and modulation technologies that can be used to treat and/or diagnose central nervous system (CNS) diseases and disorders and to better understand the human CNS, from proof of concept up to the stage of readiness for first in human (FIH) studies. Technologies may incorporate any signal modality (e.g., electrical, optical, magnetic, acoustic) or a combination thereof. Diverse team-based applications that integrate appropriate domains of expertise are encouraged.

Full NOFO in the NIH Guide Apply on Grants.gov

NOFO number
RFA-NS-24-031
Type
RFA
Activity code
R18
Primary institute
NINDS · National Institute of Neurological Disorders and Stroke
Clinical trials
Not Allowed
Posted
Mar 19, 2024
Opens
Apr 29, 2024
Expires
Jan 29, 2027

Projects funded under RFA-NS-24-031

NIH RePORTER lists 3 projects funded under RFA-NS-24-031 in FY2022–FY2026, with $3.7M in award dollars. Counts include each project's later non-competing years, which keep the original NOFO number.

Projects funded

3

Distinct projects, FY2022–FY2026

New awards

3

Type 1 (new project) award records

NIH funding

$3.7M

Award dollars under RFA-NS-24-031, FY2022–FY2026

Funding by fiscal year

Award records, new awards, and funding by fiscal year under RFA-NS-24-031
Fiscal yearAward recordsNew awardsFunding
FY202200$0
FY202300$0
FY202400$0
FY202511$976K
FY202632$2.7M

Institutions with the most funding

  1. Rutgers Biomedical and Health Sciences$1.8M · 1 project
  2. Dartmouth College$1.0M · 1 project
  3. University of California, San Diego$825K · 1 project

Funding institutes

  • NINDS$3.7M · 4

Activity codes funded

  • R184 records

Most recent new awards

FY2026 closed on September 30, 2026, but NIH keeps posting that year's awards to RePORTER for several weeks. FY2026 figures reflect records available on October 16, 2026 and may rise slightly at the next refresh.

Participating institutes

10 NIH institutes and offices take applications under RFA-NS-24-031. Contact the program officer at the institute that fits your research before applying.

  • NINDS · National Institute of Neurological Disorders and Stroke
  • NEI · National Eye Institute
  • NIA · National Institute on Aging
  • NIAAA · National Institute on Alcohol Abuse and Alcoholism
  • NIBIB · National Institute of Biomedical Imaging and Bioengineering
  • NICHD · Eunice Kennedy Shriver National Institute of Child Health and Human Development
  • NIDCD · National Institute on Deafness and Other Communication Disorders
  • NIDA · National Institute on Drug Abuse
  • NIMH · National Institute of Mental Health
  • NCCIH · National Center for Complementary and Integrative Health

Related notices

  1. Mar 31, 2025

    This funding opportunity was updated to align with agency priorities. Carefully reread the full funding opportunity and make any needed adjustments to your application prior to submission.

  2. Apr 4, 2024 · NOT-OD-24-084

    Overview of Grant Application and Review Changes for Due Dates on or after January 25, 2025.

  3. Aug 31, 2022 · NOT-OD-22-198

    Implementation Changes for Genomic Data Sharing Plans Included with Applications Due on or after January 25, 2023. See Notice NOT-OD-22-198.

  4. Aug 5, 2022 · NOT-OD-22-189

    Implementation Details for the NIH Data Management and Sharing Policy. See Notice NOT-OD-22-189.

Award terms

Application types allowed
NewResubmissionRevision The OER Glossary and the How to Apply - Application Guide provides details on these application types. Only those application types listed here are allowed for this NOFO.
Award budget
Application budgets are not limited but need to reflect the actual needs of the proposed project. Budgets should rarely exceed 750,000 direct costs per year.
Project period
The scope of the proposed project should determine the project period. The maximum project period is three years of support. NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO.
Funds available and number of awards
NINDS and partner components intend to commit an estimated total of 8 million to fund 5-7 awards. 

Summarized from the NOFO text; the full NOFO governs eligibility, budget, and review.

Related NOFOs

  • Companion NOFOs: RFA-NS-24-016, RFA-NS-24-017.

About this page

GotGrant gathers the NOFO, its participation and change notices, and its NOSIs from the NIH Guide for Grants and Contracts, and counts funded projects from NIH RePORTER by the opportunity number each award was made under. Data refreshed October 16, 2026; the NIH Guide is the authoritative source. See our data methodology.

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