NIH RFA · NIDDK · P30
RFA-DK-27-119: Silvio O. Conte Digestive Diseases Research Core Centers (P30-Clinical Trial Optional)
Reviewed by Dr. Meng ZhaoLast reviewed October 16, 2026Data refreshed October 16, 2026Editorial standards
This Notice of Funding Opportunity (NOFO) invites applications for Silvio O. Conte Digestive Diseases Research Core Centers (DDRCCs). The DDRCCs are part of an integrated program of digestive and liver diseases research support provided by the NIDDK. The purpose of this Centers program is to bring together basic and clinical investigators to enhance communication, collaboration, and effectiveness of ongoing research related to digestive and/or liver diseases within the NIDDK's mission. DDRCCs are based on the core concept, whereby shared resources aimed at fostering productivity, synergy, and new research ideas among the funded investigators are supported in a cost-effective manner. Each…
- NOFO number
- RFA-DK-27-119
- Type
- RFA
- Activity code
- P30
- Primary institute
- NIDDK · National Institute of Diabetes and Digestive and Kidney Diseases
- Clinical trials
- Optional
- Posted
- Jun 16, 2026
- Opens
- Aug 29, 2026
- Expires
- Feb 11, 2027
RFA-DK-27-119 due dates
1 application due date remains before the NOFO expires. Dates marked * are NIH standard due dates. Check the related notices below for changes NIH made after posting.
| New | Renewal / Resubmission / Revision (as allowed) | AIDS - New/Renewal/Resubmission/Revision, as allowed | Scientific Merit Review | Advisory Council Review | Earliest Start Date |
|---|---|---|---|---|---|
| September 29, 2026 | September 29, 2026 | Not Applicable | March 2027 | May 2027 | July 2027 |
| February 10, 2027 | February 10, 2027 | Not Applicable | July 2027 | October 2027 | December 2027 |
What its predecessor RFA-DK-25-003 funded
RFA-DK-27-119 reissues RFA-DK-25-003. Until awards appear under the new number, its funding history is the best guide to who wins under this program: 8 projects and $14.4M in FY2022–FY2026.
Projects funded
8
Distinct projects, FY2022–FY2026
New awards
1
Type 1 (new project) award records
NIH funding
$14.4M
Award dollars under RFA-DK-25-003, FY2022–FY2026
Funding by fiscal year
| Fiscal year | Award records | New awards | Funding |
|---|---|---|---|
| FY2022 | 0 | 0 | $0 |
| FY2023 | 0 | 0 | $0 |
| FY2024 | 0 | 0 | $0 |
| FY2025 | 4 | 0 | $4.6M |
| FY2026 | 8 | 1 | $9.8M |
Institutions with the most funding
- Case Western Reserve University$2.4M · 1 project
- Univ of North Carolina Chapel Hill$2.3M · 1 project
- Washington University$2.3M · 1 project
- Medical University of South Carolina$2.1M · 1 project
- Boston Children's Hospital$1.4M · 1 project
- Cedars-Sinai Medical Center$1.3M · 1 project
- Yale University$1.3M · 1 project
- Massachusetts General Hospital$1.2M · 1 project
Funding institutes
- NIDDK$14.4M · 12
Activity codes funded
- P3012 records
Most recent new awards
- Cedars-Sinai Digestive Diseases Research Center (opens NIH RePORTER)
Cedars-Sinai Medical Center · 1P30DK138899-01A1 · NIDDK · Notice Jun 18, 2026
$1.3MP30
FY2026 closed on September 30, 2026, but NIH keeps posting that year's awards to RePORTER for several weeks. FY2026 figures reflect records available on October 16, 2026 and may rise slightly at the next refresh.
Participating institutes
2 NIH institutes and offices take applications under RFA-DK-27-119. Contact the program officer at the institute that fits your research before applying.
- NIDDK · National Institute of Diabetes and Digestive and Kidney Diseases
- none
Related notices
Jan 23, 2026 · NOT-OD-26-031
NIH Pause on New Submissions to the NIH Human Embryonic Stem Cell Registry and Request for Information on Reducing Reliance on Human Embryonic Stem Cells in NIH-Supported Research.
Award terms
- Application types allowed
- New Renewal Resubmission The OER Glossary and the How to Apply - Application Guide provides details on these application types. Only those application types listed here are allowed for this NOFO.
- Award budget
- Application budgets are limited to 750,000 in direct costs per year and need to reflect the actual needs of the proposed Center.
- Project period
- The maximum project period is five years. NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO.
- Funds available and number of awards
- NIDDK intends to commit 4.8 million in FY 2027 to fund 4 awards and 2.4 million in FY2028 to fund 2 awards.
Summarized from the NOFO text; the full NOFO governs eligibility, budget, and review.
Related NOFOs
- Reissue of RFA-DK-25-003.
Other open NOFOs for P30
- RFA-DK-27-120Nutrition Obesity Research Centers (NORCs) (P30 Clinical Trial Optional)NIDDK · next due Oct 20, 2026
- RFA-DK-26-310Diabetes Research Centers (P30 Clinical Trial Optional)NIDDK · next due Jan 27, 2027
- PAR-28-090Centers for AIDS Research (CFAR) and Developmental Centers for AIDS Research (D-CFAR) (P30 Clinical Trial Not Allowed)NIAID · next due May 25, 2027
- PAR-27-054Limited Competition: Centers of Biomedical Research Excellence: Development Phase (COBRE-D) (P30 - Clinical Trial Not Allowed)NIGMS · next due Jan 25, 2027
- PAR-27-055Limited Competition: Centers of Biomedical Research Excellence: Expansion/Sustainability Phases (COBRE-E/S) (P30 - Clinical Trial Not Allowed)NIGMS · next due Jan 25, 2027
- PAR-25-444Cancer Center Support Grants (CCSGs) for NCI-designated Cancer Centers (P30 Clinical Trial Optional)NCI · next due Jan 25, 2027
About this page
GotGrant gathers the NOFO, its participation and change notices, and its NOSIs from the NIH Guide for Grants and Contracts, and counts funded projects from NIH RePORTER by the opportunity number each award was made under. Data refreshed October 16, 2026; the NIH Guide is the authoritative source. See our data methodology.